-
1
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan, D.; Weinberg, R.A. The hallmarks of cancer. Cell 2000, 100, 57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
2
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan, D.; Weinberg, R.A. Hallmarks of cancer: The next generation. Cell 2011, 144, 646-674.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
3
-
-
0025312728
-
A genetic model for colorectal tumorigenesis
-
Fearon, E.R.; Vogelstein, B. A genetic model for colorectal tumorigenesis. Cell 1990, 61, 759-767.
-
(1990)
Cell
, vol.61
, pp. 759-767
-
-
Fearon, E.R.1
Vogelstein, B.2
-
4
-
-
4043181214
-
Cancer genes and the pathways they control
-
Vogelstein, B.; Kinzler, K.W. Cancer genes and the pathways they control. Nat. Med. 2004, 10, 789-799.
-
(2004)
Nat. Med
, vol.10
, pp. 789-799
-
-
Vogelstein, B.1
Kinzler, K.W.2
-
5
-
-
84874072228
-
Demethylation and re-expression of epigenetically silenced tumor suppressor genes: Sensitization of cancer cells by combination therapy
-
Sarkar, S.; Goldgar, S.; Byler, S.; Rosenthal, S.; Heerboth, S. Demethylation and re-expression of epigenetically silenced tumor suppressor genes: Sensitization of cancer cells by combination therapy. Epigenomics 2013, 5, 87-94.
-
(2013)
Epigenomics
, vol.5
, pp. 87-94
-
-
Sarkar, S.1
Goldgar, S.2
Byler, S.3
Rosenthal, S.4
Heerboth, S.5
-
6
-
-
39649122136
-
Cancer epigenetics: Modifications, screening, and therapy
-
Gal-Yam, E.N.; Saito, Y.; Egger, G.; Jones, P.A. Cancer epigenetics: Modifications, screening, and therapy. Annu. Rev. Med. 2008, 59, 267-280.
-
(2008)
Annu. Rev. Med
, vol.59
, pp. 267-280
-
-
Gal-Yam, E.N.1
Saito, Y.2
Egger, G.3
Jones, P.A.4
-
7
-
-
0022540321
-
CpG-rich islands and the function of DNA methylation
-
Bird, A.P. CpG-rich islands and the function of DNA methylation. Nature 1986, 321, 209-213.
-
(1986)
Nature
, vol.321
, pp. 209-213
-
-
Bird, A.P.1
-
8
-
-
0029011539
-
5 CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers
-
Merlo, A.; Herman, J.G.; Mao, L.; Lee, D.J.; Gabrielson, E.; Burger, P.C.; Baylin, S.B.; Sidransky, D. 5 CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers. Nat. Med. 1995, 1, 686-692.
-
(1995)
Nat. Med
, vol.1
, pp. 686-692
-
-
Merlo, A.1
Herman, J.G.2
Mao, L.3
Lee, D.J.4
Gabrielson, E.5
Burger, P.C.6
Baylin, S.B.7
Sidransky, D.8
-
10
-
-
8544284078
-
The epigenetics of ovarian cancer drug resistance and resensitization
-
Balch, C.; Huang, T.H.; Brown, R.; Nephew, K.P. The epigenetics of ovarian cancer drug resistance and resensitization. Am. J. Obstet. Gynecol. 2004, 191, 1552-1572.
-
(2004)
Am. J. Obstet. Gynecol
, vol.191
, pp. 1552-1572
-
-
Balch, C.1
Huang, T.H.2
Brown, R.3
Nephew, K.P.4
-
11
-
-
0030929794
-
Cytosine methylation determines hot spots of DNA damage in the human P53 gene
-
Denissenko, M.F.; Chen, J.X.; Tang, M.S.; Pfeifer, G.P. Cytosine methylation determines hot spots of DNA damage in the human P53 gene. Proc. Natl. Acad. Sci. USA 1997, 94, 3893-3898.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 3893-3898
-
-
Denissenko, M.F.1
Chen, J.X.2
Tang, M.S.3
Pfeifer, G.P.4
-
12
-
-
33845943192
-
Apoptosis, proliferation and differentiation patterns are influenced by Zebularine and SAHA in pancreatic cancer models
-
Neureiter, D.; Zopf, S.; Leu, T.; Dietze, O.; Hauser-Kronberger, C.; Hahn, E.G.; Herold, C.; Ocker, M. Apoptosis, proliferation and differentiation patterns are influenced by Zebularine and SAHA in pancreatic cancer models. Scand. J. Gastroenterol. 2007, 42, 103-116.
-
(2007)
Scand. J. Gastroenterol
, vol.42
, pp. 103-116
-
-
Neureiter, D.1
Zopf, S.2
Leu, T.3
Dietze, O.4
Hauser-Kronberger, C.5
Hahn, E.G.6
Herold, C.7
Ocker, M.8
-
13
-
-
59249103688
-
Cancer prevention: Epigenetics steps up to the plate
-
Issa, J.P. Cancer prevention: Epigenetics steps up to the plate. Cancer Prev. Res. (Phila.) 2008, 1, 219-222.
-
(2008)
Cancer Prev. Res. (Phila.)
, vol.1
, pp. 219-222
-
-
Issa, J.P.1
-
14
-
-
27944508740
-
Impaired retinoic acid (RA) signal leads to RARβ2 epigenetic silencing and RA resistance
-
Ren, M.; Pozzi, S.; Bistulfi, G.; Somenzi, G.; Rossetti, S.; Sacchi, N. Impaired retinoic acid (RA) signal leads to RARβ2 epigenetic silencing and RA resistance. Mol. Cell. Biol. 2005, 25, 10591-10603.
-
(2005)
Mol. Cell. Biol
, vol.25
, pp. 10591-10603
-
-
Ren, M.1
Pozzi, S.2
Bistulfi, G.3
Somenzi, G.4
Rossetti, S.5
Sacchi, N.6
-
15
-
-
0036274359
-
The fundamental role of epigenetic events in cancer
-
Jones, P.A.; Baylin, S.B. The fundamental role of epigenetic events in cancer. Nat. Rev. Genet. 2002, 3, 415-428.
-
(2002)
Nat. Rev. Genet
, vol.3
, pp. 415-428
-
-
Jones, P.A.1
Baylin, S.B.2
-
16
-
-
0037354548
-
Epigenetic regulation of ARHI in breast and ovarian cancer cells
-
Yu, Y.; Fujii, S.; Yuan, J.; Luo, R.Z.; Wang, L.; Bao, J.; Kadota, M.; Oshimura, M.; Dent, S.R.; Issa, J.P.; et al. Epigenetic regulation of ARHI in breast and ovarian cancer cells. Ann. N. Y. Acad. Sci. 2003, 983, 268-277.
-
(2003)
Ann. N. Y. Acad. Sci
, vol.983
, pp. 268-277
-
-
Yu, Y.1
Fujii, S.2
Yuan, J.3
Luo, R.Z.4
Wang, L.5
Bao, J.6
Kadota, M.7
Oshimura, M.8
Dent, S.R.9
Issa, J.P.10
-
17
-
-
84865688852
-
Anti-breast cancer effects of histone deacetylase inhibitors and calpain inhibitor
-
Mataga, M.A.; Rosenthal, S.; Heerboth, S.; Devalapalli, A.; Kokolus, S.; Evans, L.R.; Longacre, M.; Housman, G.; Sarkar, S. Anti-breast cancer effects of histone deacetylase inhibitors and calpain inhibitor. Anticancer Res. 2012, 32, 2523-2529.
-
(2012)
Anticancer Res
, vol.32
, pp. 2523-2529
-
-
Mataga, M.A.1
Rosenthal, S.2
Heerboth, S.3
Devalapalli, A.4
Kokolus, S.5
Evans, L.R.6
Longacre, M.7
Housman, G.8
Sarkar, S.9
-
19
-
-
20044372154
-
MGMT gene silencing and benefit from temozolomide in glioblastoma
-
Hegi, M.E.; Diserens, A.C.; Gorlia, T.; Hamou, M.F.; de Tribolet, N.; Weller, M.; Kros, J.M.; Hainfellner, J.A.; Mason, W.; Mariani, L.; et al. MGMT gene silencing and benefit from temozolomide in glioblastoma. N. Engl. J. Med. 2005, 352, 997-1003.
-
(2005)
N. Engl. J. Med
, vol.352
, pp. 997-1003
-
-
Hegi, M.E.1
Diserens, A.C.2
Gorlia, T.3
Hamou, M.F.4
De Tribolet, N.5
Weller, M.6
Kros, J.M.7
Hainfellner, J.A.8
Mason, W.9
Mariani, L.10
-
20
-
-
84879724501
-
MGMT promoter methylation and glioblastoma prognosis: A systematic review and meta-analysis
-
Chen, Y.; Hu, F.; Zhou, Y.; Chen, W.; Shao, H.; Zhang, Y. MGMT promoter methylation and glioblastoma prognosis: A systematic review and meta-analysis. Arch. Med. Res. 2013, 44, 281-290.
-
(2013)
Arch. Med. Res
, vol.44
, pp. 281-290
-
-
Chen, Y.1
Hu, F.2
Zhou, Y.3
Chen, W.4
Shao, H.5
Zhang, Y.6
-
21
-
-
0034658196
-
Differential mRNA expression of the human DNA methyltransferases (DNMTs) 1, 3a and 3b during the G0/G1 to S phase transition in normal and tumor cells
-
Robertson, K.D.; Keyomarsi, K.; Gonzales, F.A.; Velicescu, M.; Jones, P.A. Differential mRNA expression of the human DNA methyltransferases (DNMTs) 1, 3a and 3b during the G0/G1 to S phase transition in normal and tumor cells. Nucleic Acids Res. 2000, 28, 2108-2113.
-
(2000)
Nucleic Acids Res
, vol.28
, pp. 2108-2113
-
-
Robertson, K.D.1
Keyomarsi, K.2
Gonzales, F.A.3
Velicescu, M.4
Jones, P.A.5
-
22
-
-
33748451151
-
Anticancer activities of histone deacetylase inhibitors
-
Bolden, J.E.; Peart, M.J.; Johnstone, R.W. Anticancer activities of histone deacetylase inhibitors. Nat. Rev. Drug Discov. 2006, 5, 769-784.
-
(2006)
Nat. Rev. Drug Discov
, vol.5
, pp. 769-784
-
-
Bolden, J.E.1
Peart, M.J.2
Johnstone, R.W.3
-
23
-
-
79952384705
-
Cancer epigenetics reaches mainstream oncology
-
Rodriguez-Paredes, M.; Esteller, M. Cancer epigenetics reaches mainstream oncology. Nat. Med. 2011, 17, 330-339.
-
(2011)
Nat. Med
, vol.17
, pp. 330-339
-
-
Rodriguez-Paredes, M.1
Esteller, M.2
-
24
-
-
84869087517
-
Association of UHRF1 with methylated H3K9 directs the maintenance of DNA methylation
-
Rothbart, S.B.; Krajewski, K.; Nady, N.; Tempel, W.; Xue, S.; Badeaux, A.I.; Barsyte-Lovejoy, D.; Martinez, J.Y.; Bedford, M.T.; Fuchs, S.M.; et al. Association of UHRF1 with methylated H3K9 directs the maintenance of DNA methylation. Nat. Struct. Mol. Biol. 2012, 19, 1155-1160.
-
(2012)
Nat. Struct. Mol. Biol
, vol.19
, pp. 1155-1160
-
-
Rothbart, S.B.1
Krajewski, K.2
Nady, N.3
Tempel, W.4
Xue, S.5
Badeaux, A.I.6
Barsyte-Lovejoy, D.7
Martinez, J.Y.8
Bedford, M.T.9
Fuchs, S.M.10
-
25
-
-
66149123748
-
The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain
-
Kriaucionis, S.; Heintz, N. The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain. Science 2009, 324, 929-930.
-
(2009)
Science
, vol.324
, pp. 929-930
-
-
Kriaucionis, S.1
Heintz, N.2
-
26
-
-
66149146320
-
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1
-
Tahiliani, M.; Koh, K.P.; Shen, Y.; Pastor, W.A.; Bandukwala, H.; Brudno, Y.; Agarwal, S.; Iyer, L.M.; Liu, D.R.; Aravind, L.; et al. Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science 2009, 324, 930-935.
-
(2009)
Science
, vol.324
, pp. 930-935
-
-
Tahiliani, M.1
Koh, K.P.2
Shen, Y.3
Pastor, W.A.4
Bandukwala, H.5
Brudno, Y.6
Agarwal, S.7
Iyer, L.M.8
Liu, D.R.9
Aravind, L.10
-
27
-
-
84877582944
-
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX
-
Ko, M.; An, J.; Bandukwala, H.S.; Chavez, L.; Aijo, T.; Pastor, W.A.; Segal, M.F.; Li, H.; Koh, K.P.; Lahdesmaki, H.; et al. Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX. Nature 2013, 497, 122-126.
-
(2013)
Nature
, vol.497
, pp. 122-126
-
-
Ko, M.1
An, J.2
Bandukwala, H.S.3
Chavez, L.4
Aijo, T.5
Pastor, W.A.6
Segal, M.F.7
Li, H.8
Koh, K.P.9
Lahdesmaki, H.10
-
28
-
-
84875783959
-
Different roles for Tet1 and Tet2 proteins in reprogramming-mediated erasure of imprints induced by EGC fusion
-
Piccolo, F.M.; Bagci, H.; Brown, K.E.; Landeira, D.; Soza-Ried, J.; Feytout, A.; Mooijman, D.; Hajkova, P.; Leitch, H.G.; Tada, T.; et al. Different roles for Tet1 and Tet2 proteins in reprogramming-mediated erasure of imprints induced by EGC fusion. Mol. Cell 2013, 49, 1023-1033.
-
(2013)
Mol. Cell
, vol.49
, pp. 1023-1033
-
-
Piccolo, F.M.1
Bagci, H.2
Brown, K.E.3
Landeira, D.4
Soza-Ried, J.5
Feytout, A.6
Mooijman, D.7
Hajkova, P.8
Leitch, H.G.9
Tada, T.10
-
29
-
-
80053348585
-
The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes
-
Gu, T.P.; Guo, F.; Yang, H.; Wu, H.P.; Xu, G.F.; Liu, W.; Xie, Z.G.; Shi, L.; He, X.; Jin, S.G.; et al. The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes. Nature 2011, 477, 606-610.
-
(2011)
Nature
, vol.477
, pp. 606-610
-
-
Gu, T.P.1
Guo, F.2
Yang, H.3
Wu, H.P.4
Xu, G.F.5
Liu, W.6
Xie, Z.G.7
Shi, L.8
He, X.9
Jin, S.G.10
-
30
-
-
79952763586
-
Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine
-
Iqbal, K.; Jin, S.G.; Pfeifer, G.P.; Szabo, P.E. Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine. Proc. Natl. Acad. Sci. USA 2011, 108, 3642-3647.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 3642-3647
-
-
Iqbal, K.1
Jin, S.G.2
Pfeifer, G.P.3
Szabo, P.E.4
-
31
-
-
79952713567
-
5-Hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming
-
doi:10.1038/ncomms1240
-
Wossidlo, M.; Nakamura, T.; Lepikhov, K.; Marques, C.J.; Zakhartchenko, V.; Boiani, M.; Arand, J.; Nakano, T.; Reik, W.; Walter, J. 5-Hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming. Nat. Commun. 2011, 2, doi:10.1038/ncomms1240.
-
(2011)
Nat. Commun
, pp. 2
-
-
Wossidlo, M.1
Nakamura, T.2
Lepikhov, K.3
Marques, C.J.4
Zakhartchenko, V.5
Boiani, M.6
Arand, J.7
Nakano, T.8
Reik, W.9
Walter, J.10
-
32
-
-
84856058152
-
Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers
-
Haffner, M.C.; Chaux, A.; Meeker, A.K.; Esopi, D.M.; Gerber, J.; Pellakuru, L.G.; Toubaji, A.; Argani, P.; Iacobuzio-Donahue, C.; Nelson, W.G.; et al. Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers. Oncotarget 2011, 2, 627-637.
-
(2011)
Oncotarget
, vol.2
, pp. 627-637
-
-
Haffner, M.C.1
Chaux, A.2
Meeker, A.K.3
Esopi, D.M.4
Gerber, J.5
Pellakuru, L.G.6
Toubaji, A.7
Argani, P.8
Iacobuzio-Donahue, C.9
Nelson, W.G.10
-
33
-
-
66249137734
-
Mutation in TET2 in myeloid cancers
-
Delhommeau, F.; Dupont, S.; Della Valle, V.; James, C.; Trannoy, S.; Masse, A.; Kosmider, O.; Le Couedic, J.P.; Robert, F.; Alberdi, A.; et al. Mutation in TET2 in myeloid cancers. N. Engl. J. Med. 2009, 360, 2289-2301.
-
(2009)
N. Engl. J. Med
, vol.360
, pp. 2289-2301
-
-
Delhommeau, F.1
Dupont, S.2
della Valle, V.3
James, C.4
Trannoy, S.5
Masse, A.6
Kosmider, O.7
Le Couedic, J.P.8
Robert, F.9
Alberdi, A.10
-
34
-
-
67649876132
-
Acquired mutations in TET2 are common in myelodysplastic syndromes
-
Langemeijer, S.M.; Kuiper, R.P.; Berends, M.; Knops, R.; Aslanyan, M.G.; Massop, M.; Stevens-Linders, E.; van Hoogen, P.; Van Kessel, A.G.; Raymakers, R.A.; et al. Acquired mutations in TET2 are common in myelodysplastic syndromes. Nat. Genet. 2009, 41, 838-842.
-
(2009)
Nat. Genet
, vol.41
, pp. 838-842
-
-
Langemeijer, S.M.1
Kuiper, R.P.2
Berends, M.3
Knops, R.4
Aslanyan, M.G.5
Massop, M.6
Stevens-Linders, E.7
Van Hoogen, P.8
Van Kessel, A.G.9
Raymakers, R.A.10
-
35
-
-
0037099537
-
LCX, leukemia-associated protein with a CXXC domain, is fused to MLL in acute myeloid leukemia with trilineage dysplasia having t(10;11)(q22;q23)
-
Ono, R.; Taki, T.; Taketani, T.; Taniwaki, M.; Kobayashi, H.; Hayashi, Y. LCX, leukemia-associated protein with a CXXC domain, is fused to MLL in acute myeloid leukemia with trilineage dysplasia having t(10;11)(q22;q23). Cancer Res. 2002, 62, 4075-4080.
-
(2002)
Cancer Res
, vol.62
, pp. 4075-4080
-
-
Ono, R.1
Taki, T.2
Taketani, T.3
Taniwaki, M.4
Kobayashi, H.5
Hayashi, Y.6
-
36
-
-
0037350661
-
TET1, a member of a novel protein family, is fused to MLL in acute myeloid leukemia containing the t(10;11)(q22;q23)
-
Lorsbach, R.B.; Moore, J.; Mathew, S.; Raimondi, S.C.; Mukatira, S.T.; Downing, J.R. TET1, a member of a novel protein family, is fused to MLL in acute myeloid leukemia containing the t(10;11)(q22;q23). Leukemia 2003, 17, 637-641.
-
(2003)
Leukemia
, vol.17
, pp. 637-641
-
-
Lorsbach, R.B.1
Moore, J.2
Mathew, S.3
Raimondi, S.C.4
Mukatira, S.T.5
Downing, J.R.6
-
37
-
-
84873411803
-
Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation
-
Yang, H.; Liu, Y.; Bai, F.; Zhang, J.Y.; Ma, S.H.; Liu, J.; Xu, Z.D.; Zhu, H.G.; Ling, Z.Q.; Ye, D.; et al. Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation. Oncogene 2013, 32, 663-669.
-
(2013)
Oncogene
, vol.32
, pp. 663-669
-
-
Yang, H.1
Liu, Y.2
Bai, F.3
Zhang, J.Y.4
Ma, S.H.5
Liu, J.6
Xu, Z.D.7
Zhu, H.G.8
Ling, Z.Q.9
Ye, D.10
-
38
-
-
84877336241
-
Decrease of 5-hydroxymethylcytosine is associated with progression of hepatocellular carcinoma through downregulation of TET1
-
Liu, C.; Liu, L.; Chen, X.; Shen, J.; Shan, J.; Xu, Y.; Yang, Z.; Wu, L.; Xia, F.; Bie, P.; et al. Decrease of 5-hydroxymethylcytosine is associated with progression of hepatocellular carcinoma through downregulation of TET1. PLoS One 2013, 8, e62828.
-
(2013)
PLoS One
, vol.8
-
-
Liu, C.1
Liu, L.2
Chen, X.3
Shen, J.4
Shan, J.5
Xu, Y.6
Yang, Z.7
Wu, L.8
Xia, F.9
Bie, P.10
-
39
-
-
84866419591
-
Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma
-
Lian, C.G.; Xu, Y.; Ceol, C.; Wu, F.; Larson, A.; Dresser, K.; Xu, W.; Tan, L.; Hu, Y.; Zhan, Q.; et al. Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma. Cell 2012, 150, 1135-1146.
-
(2012)
Cell
, vol.150
, pp. 1135-1146
-
-
Lian, C.G.1
Xu, Y.2
Ceol, C.3
Wu, F.4
Larson, A.5
Dresser, K.6
Xu, W.7
Tan, L.8
Hu, Y.9
Zhan, Q.10
-
40
-
-
72049125350
-
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
-
Dang, L.; White, D.W.; Gross, S.; Bennett, B.D.; Bittinger, M.A.; Driggers, E.M.; Fantin, V.R.; Jang, H.G.; Jin, S.; Keenan, M.C.; et al. Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Nature 2009, 462, 739-744.
-
(2009)
Nature
, vol.462
, pp. 739-744
-
-
Dang, L.1
White, D.W.2
Gross, S.3
Bennett, B.D.4
Bittinger, M.A.5
Driggers, E.M.6
Fantin, V.R.7
Jang, H.G.8
Jin, S.9
Keenan, M.C.10
-
41
-
-
64849098267
-
Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1α
-
Zhao, S.; Lin, Y.; Xu, W.; Jiang, W.; Zha, Z.; Wang, P.; Yu, W.; Li, Z.; Gong, L.; Peng, Y.; et al. Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1α. Science 2009, 324, 261-265.
-
(2009)
Science
, vol.324
, pp. 261-265
-
-
Zhao, S.1
Lin, Y.2
Xu, W.3
Jiang, W.4
Zha, Z.5
Wang, P.6
Yu, W.7
Li, Z.8
Gong, L.9
Peng, Y.10
-
42
-
-
82255183051
-
Ollier disease and Maffucci syndrome are caused by somatic mosaic mutations of IDH1 and IDH2
-
Amary, M.F.; Damato, S.; Halai, D.; Eskandarpour, M.; Berisha, F.; Bonar, F.; McCarthy, S.; Fantin, V.R.; Straley, K.S.; Lobo, S.; et al. Ollier disease and Maffucci syndrome are caused by somatic mosaic mutations of IDH1 and IDH2. Nat. Genet. 2011, 43, 1262-1265.
-
(2011)
Nat. Genet
, vol.43
, pp. 1262-1265
-
-
Amary, M.F.1
Damato, S.2
Halai, D.3
Eskandarpour, M.4
Berisha, F.5
Bonar, F.6
McCarthy, S.7
Fantin, V.R.8
Straley, K.S.9
Lobo, S.10
-
43
-
-
82255183048
-
Somatic mosaic IDH1 and IDH2 mutations are associated with enchondroma and spindle cell hemangioma in Ollier disease and Maffucci syndrome
-
Pansuriya, T.C.; Van Eijk, R.; d'Adamo, P.; Van Ruler, M.A.; Kuijjer, M.L.; Oosting, J.; Cleton-Jansen, A.M.; van Oosterwijk, J.G.; Verbeke, S.L.; Meijer, D.; et al. Somatic mosaic IDH1 and IDH2 mutations are associated with enchondroma and spindle cell hemangioma in Ollier disease and Maffucci syndrome. Nat. Genet. 2011, 43, 1256-1261.
-
(2011)
Nat. Genet
, vol.43
, pp. 1256-1261
-
-
Pansuriya, T.C.1
Van Eijk, R.2
Dadamo, P.3
Van Ruler, M.A.4
Kuijjer, M.L.5
Oosting, J.6
Cleton-Jansen, A.M.7
Van Oosterwijk, J.G.8
Verbeke, S.L.9
Meijer, D.10
-
44
-
-
52949127312
-
An integrated genomic analysis of human glioblastoma multiforme
-
Parsons, D.W.; Jones, S.; Zhang, X.; Lin, J.C.; Leary, R.J.; Angenendt, P.; Mankoo, P.; Carter, H.; Siu, I.M.; Gallia, G.L.; et al. An integrated genomic analysis of human glioblastoma multiforme. Science 2008, 321, 1807-1812.
-
(2008)
Science
, vol.321
, pp. 1807-1812
-
-
Parsons, D.W.1
Jones, S.2
Zhang, X.3
Lin, J.C.4
Leary, R.J.5
Angenendt, P.6
Mankoo, P.7
Carter, H.8
Siu, I.M.9
Gallia, G.L.10
-
45
-
-
77957835307
-
Identification of several novel non-p.R132 IDH1 variants in thyroid carcinomas
-
Hemerly, J.P.; Bastos, A.U.; Cerutti, J.M. Identification of several novel non-p.R132 IDH1 variants in thyroid carcinomas. Eur. J. Endocrinol. 2010, 163, 747-755.
-
(2010)
Eur. J. Endocrinol
, vol.163
, pp. 747-755
-
-
Hemerly, J.P.1
Bastos, A.U.2
Cerutti, J.M.3
-
46
-
-
77949262337
-
Identification and functional characterization of isocitrate dehydrogenase 1 (IDH1) mutations in thyroid cancer
-
Murugan, A.K.; Bojdani, E.; Xing, M. Identification and functional characterization of isocitrate dehydrogenase 1 (IDH1) mutations in thyroid cancer. Biochem. Biophys. Res. Commun. 2010, 393, 555-559.
-
(2010)
Biochem. Biophys. Res. Commun
, vol.393
, pp. 555-559
-
-
Murugan, A.K.1
Bojdani, E.2
Xing, M.3
-
47
-
-
80052461558
-
Test proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine
-
Ito, S.; Shen, L.; Dai, Q.; Wu, S.C.; Collins, L.B.; Swenberg, J.A.; He, C.; Zhang, Y. Test proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine. Science 2011, 333, 1300-1303.
-
(2011)
Science
, vol.333
, pp. 1300-1303
-
-
Ito, S.1
Shen, L.2
Dai, Q.3
Wu, S.C.4
Collins, L.B.5
Swenberg, J.A.6
He, C.7
Zhang, Y.8
-
48
-
-
84887231258
-
Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase
-
doi:10.1038/cr.2013.107
-
Xu, S.; Li, W.; Zhu, J.; Wang, R.; Li, Z.; Xu, G.L.; Ding, J. Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase. Cell Res. 2013, doi:10.1038/cr.2013.107.
-
(2013)
Cell Res
-
-
Xu, S.1
Li, W.2
Zhu, J.3
Wang, R.4
Li, Z.5
Xu, G.L.6
Ding, J.7
-
49
-
-
80052495940
-
Test-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA
-
He, Y.F.; Li, B.Z.; Li, Z.; Liu, P.; Wang, Y.; Tang, Q.; Ding, J.; Jia, Y.; Chen, Z.; Li, L.; et al. Test-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA. Science 2011, 333, 1303-1307.
-
(2011)
Science
, vol.333
, pp. 1303-1307
-
-
He, Y.F.1
Li, B.Z.2
Li, Z.3
Liu, P.4
Wang, Y.5
Tang, Q.6
Ding, J.7
Jia, Y.8
Chen, Z.9
Li, L.10
-
50
-
-
80053917872
-
Thymine DNA glycosylase can rapidly excise 5-formylcytosine and 5-carboxylcytosine: Potential implications for active demethylation of CpG sites
-
Maiti, A.; Drohat, A.C. Thymine DNA glycosylase can rapidly excise 5-formylcytosine and 5-carboxylcytosine: Potential implications for active demethylation of CpG sites. J. Biol. Chem. 2011, 286, 35334-35338.
-
(2011)
J. Biol. Chem
, vol.286
, pp. 35334-35338
-
-
Maiti, A.1
Drohat, A.C.2
-
51
-
-
84862776719
-
Thymine DNA glycosylase specifically recognizes 5-carboxylcytosine-modified DNA
-
Zhang, L.; Lu, X.; Lu, J.; Liang, H.; Dai, Q.; Xu, G.L.; Luo, C.; Jiang, H.; He, C. Thymine DNA glycosylase specifically recognizes 5-carboxylcytosine-modified DNA. Nat. Chem. Biol. 2012, 8, 328-330.
-
(2012)
Nat. Chem. Biol
, vol.8
, pp. 328-330
-
-
Zhang, L.1
Lu, X.2
Lu, J.3
Liang, H.4
Dai, Q.5
Xu, G.L.6
Luo, C.7
Jiang, H.8
He, C.9
-
52
-
-
79955538247
-
Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain
-
Guo, J.U.; Su, Y.; Zhong, C.; Ming, G.L.; Song, H. Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain. Cell 2011, 145, 423-434.
-
(2011)
Cell
, vol.145
, pp. 423-434
-
-
Guo, J.U.1
Su, Y.2
Zhong, C.3
Ming, G.L.4
Song, H.5
-
53
-
-
79959937861
-
Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair
-
Cortellino, S.; Xu, J.; Sannai, M.; Moore, R.; Caretti, E.; Cigliano, A.; Le Coz, M.; Devarajan, K.; Wessels, A.; Soprano, D.; et al. Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair. Cell 2011, 146, 67-79.
-
(2011)
Cell
, vol.146
, pp. 67-79
-
-
Cortellino, S.1
Xu, J.2
Sannai, M.3
Moore, R.4
Caretti, E.5
Cigliano, A.6
Le Coz, M.7
Devarajan, K.8
Wessels, A.9
Soprano, D.10
-
54
-
-
79959431845
-
Recognition of 5-hydroxymethylcytosine by the Uhrf1 SRA domain
-
Frauer, C.; Hoffmann, T.; Bultmann, S.; Casa, V.; Cardoso, M.C.; Antes, I.; Leonhardt, H. Recognition of 5-hydroxymethylcytosine by the Uhrf1 SRA domain. PLoS One 2011, 6, e21306.
-
(2011)
PLoS One
, vol.6
-
-
Frauer, C.1
Hoffmann, T.2
Bultmann, S.3
Casa, V.4
Cardoso, M.C.5
Antes, I.6
Leonhardt, H.7
-
55
-
-
84455167621
-
Mbd3/NURD complex regulates expression of 5-hydroxymethylcytosine marked genes in embryonic stem cells
-
Yildirim, O.; Li, R.; Hung, J.H.; Chen, P.B.; Dong, X.; Ee, L.S.; Weng, Z.; Rando, O.J.; Fazzio, T.G. Mbd3/NURD complex regulates expression of 5-hydroxymethylcytosine marked genes in embryonic stem cells. Cell 2011, 147, 1498-1510.
-
(2011)
Cell
, vol.147
, pp. 1498-1510
-
-
Yildirim, O.1
Li, R.2
Hung, J.H.3
Chen, P.B.4
Dong, X.5
Ee, L.S.6
Weng, Z.7
Rando, O.J.8
Fazzio, T.G.9
-
56
-
-
0032575688
-
The Bcl-2 protein family: Arbiters of cell survival
-
Adams, J.M.; Cory, S. The Bcl-2 protein family: Arbiters of cell survival. Science 1998, 281, 1322-1326.
-
(1998)
Science
, vol.281
, pp. 1322-1326
-
-
Adams, J.M.1
Cory, S.2
-
57
-
-
84856718606
-
Fast death receptor signalling: Roles of Bid and XIAP
-
Kaufmann, T.; Strasser, A.; Jost, P.J. Fast death receptor signalling: Roles of Bid and XIAP. Cell Death Differ. 2012, 19, 42-50.
-
(2012)
Cell Death Differ
, vol.19
, pp. 42-50
-
-
Kaufmann, T.1
Strasser, A.2
Jost, P.J.3
-
58
-
-
84876094622
-
FLIP: A flop for execution signals
-
Subramaniam, K.; Hirpara, J.L.; Tucker-Kellogg, L.; Tucker-Kellogg, G.; Pervaiz, S. FLIP: A flop for execution signals. Cancer Lett. 2013, 332, 151-155.
-
(2013)
Cancer Lett
, vol.332
, pp. 151-155
-
-
Subramaniam, K.1
Hirpara, J.L.2
Tucker-Kellogg, L.3
Tucker-Kellogg, G.4
Pervaiz, S.5
-
59
-
-
21344474349
-
Contribution of epigenetic silencing of tumor necrosis factor-related apoptosis inducing ligand receptor 1 (DR4) to TRAIL resistance and ovarian cancer
-
Horak, P.; Pils, D.; Haller, G.; Pribill, I.; Roessler, M.; Tomek, S.; Horvat, R.; Zeillinger, R.; Zielinski, C.; Krainer, M. Contribution of epigenetic silencing of tumor necrosis factor-related apoptosis inducing ligand receptor 1 (DR4) to TRAIL resistance and ovarian cancer. Mol. Cancer Res. 2005, 3, 335-343.
-
(2005)
Mol. Cancer Res
, vol.3
, pp. 335-343
-
-
Horak, P.1
Pils, D.2
Haller, G.3
Pribill, I.4
Roessler, M.5
Tomek, S.6
Horvat, R.7
Zeillinger, R.8
Zielinski, C.9
Krainer, M.10
-
60
-
-
84878225462
-
Telomere-homologous G-rich oligonucleotides sensitize human ovarian cancer cells to TRAIL-induced growth inhibition and apoptosis
-
Sarkar, S.; Faller, D.V. Telomere-homologous G-rich oligonucleotides sensitize human ovarian cancer cells to TRAIL-induced growth inhibition and apoptosis. Nucleic Acid Ther. 2013, 23, 167-174.
-
(2013)
Nucleic Acid Ther
, vol.23
, pp. 167-174
-
-
Sarkar, S.1
Faller, D.V.2
-
61
-
-
69349087479
-
Anti- and pro-tumor functions of autophagy
-
Morselli, E.; Galluzzi, L.; Kepp, O.; Vicencio, J.M.; Criollo, A.; Maiuri, M.C.; Kroemer, G. Anti- and pro-tumor functions of autophagy. Biochim. Biophys. Acta 2009, 1793, 1524-1532.
-
(2009)
Biochim. Biophys. Acta
, vol.1793
, pp. 1524-1532
-
-
Morselli, E.1
Galluzzi, L.2
Kepp, O.3
Vicencio, J.M.4
Criollo, A.5
Maiuri, M.C.6
Kroemer, G.7
-
62
-
-
84872813218
-
Dietary phytochemicals Prevention cancer Nrf2 signaling, epigenetics, and cell death mechanisms in blocking cancer initiation and progression
-
Lee, J.H.; Khor, T.O.; Shu, L.; Su, Z.Y.; Fuentes, F.; Kong, A.N. Dietary phytochemicals and cancer prevention: Nrf2 signaling, epigenetics, and cell death mechanisms in blocking cancer initiation and progression. Pharmacol. Ther. 2013, 137, 153-171.
-
(2013)
Pharmacol. Ther
, vol.137
, pp. 153-171
-
-
Lee, J.H.1
Khor, T.O.2
Shu, L.3
Su, Z.Y.4
Fuentes, F.5
Kong, A.N.6
-
63
-
-
26444451123
-
Reversal of hypermethylation and reactivation of p16INK4a, RARβ, and MGMT genes by genistein and other isoflavones from soy
-
Fang, M.Z.; Chen, D.; Sun, Y.; Jin, Z.; Christman, J.K.; Yang, C.S. Reversal of hypermethylation and reactivation of p16INK4a, RARβ, and MGMT genes by genistein and other isoflavones from soy. Clin. Cancer Res. 2005, 11, 7033-7041.
-
(2005)
Clin. Cancer Res
, vol.11
, pp. 7033-7041
-
-
Fang, M.Z.1
Chen, D.2
Sun, Y.3
Jin, Z.4
Christman, J.K.5
Yang, C.S.6
-
64
-
-
34247625135
-
Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells
-
Tan, J.; Yang, X.; Zhuang, L.; Jiang, X.; Chen, W.; Lee, P.L.; Karuturi, R.K.; Tan, P.B.; Liu, E.T.; Yu, Q. Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells. Genes Dev. 2007, 21, 1050-1063.
-
(2007)
Genes Dev
, vol.21
, pp. 1050-1063
-
-
Tan, J.1
Yang, X.2
Zhuang, L.3
Jiang, X.4
Chen, W.5
Lee, P.L.6
Karuturi, R.K.7
Tan, P.B.8
Liu, E.T.9
Yu, Q.10
-
65
-
-
64349123107
-
Autophagy mediates the mitotic senescence transition
-
Young, A.R.; Narita, M.; Ferreira, M.; Kirschner, K.; Sadaie, M.; Darot, J.F.; Tavare, S.; Arakawa, S.; Shimizu, S.; Watt, F.M.; et al. Autophagy mediates the mitotic senescence transition. Genes Dev. 2009, 23, 798-803.
-
(2009)
Genes Dev
, vol.23
, pp. 798-803
-
-
Young, A.R.1
Narita, M.2
Ferreira, M.3
Kirschner, K.4
Sadaie, M.5
Darot, J.F.6
Tavare, S.7
Arakawa, S.8
Shimizu, S.9
Watt, F.M.10
-
66
-
-
20944450160
-
Combinatorial micro RNA target predictions
-
Krek, A.; Grun, D.; Poy, M.N.; Wolf, R.; Rosenberg, L.; Epstein, E.J.; MacMenamin, P.; da Piedade, I.; Gunsalus, K.C.; Stoffel, M.; et al. Combinatorial micro RNA target predictions. Nat. Genet. 2005, 37, 495-500.
-
(2005)
Nat. Genet
, vol.37
, pp. 495-500
-
-
Krek, A.1
Grun, D.2
Poy, M.N.3
Wolf, R.4
Rosenberg, L.5
Epstein, E.J.6
Macmenamin, P.7
da Piedade, I.8
Gunsalus, K.C.9
Stoffel, M.10
-
67
-
-
84883027905
-
Comprehensive microRNA profiling of prostate cancer
-
Walter, B.A.; Valera, V.A.; Pinto, P.A.; Merino, M.J. Comprehensive microRNA profiling of prostate cancer. J. Cancer 2013, 4, 350-357.
-
(2013)
J. Cancer
, vol.4
, pp. 350-357
-
-
Walter, B.A.1
Valera, V.A.2
Pinto, P.A.3
Merino, M.J.4
-
68
-
-
84879288418
-
MicroRNA 100: A context dependent miRNA in prostate cancer
-
Leite, K.R.; Morais, D.R.; Reis, S.T.; Viana, N.; Moura, C.; Florez, M.G.; Silva, I.A.; Dip, N.; Srougi, M. MicroRNA 100: A context dependent miRNA in prostate cancer. Clinics (Sao Paulo) 2013, 68, 797-802.
-
(2013)
Clinics (Sao Paulo)
, vol.68
, pp. 797-802
-
-
Leite, K.R.1
Morais, D.R.2
Reis, S.T.3
Viana, N.4
Moura, C.5
Florez, M.G.6
Silva, I.A.7
Dip, N.8
Srougi, M.9
-
69
-
-
33750370444
-
Micro RNA signatures in human cancers
-
Calin, G.A.; Croce, C.M. Micro RNA signatures in human cancers. Nat. Rev. Cancer 2006, 6, 857-866.
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 857-866
-
-
Calin, G.A.1
Croce, C.M.2
-
70
-
-
77952671554
-
Micro RNAs in ovarian cancer biology and therapy resistance
-
Van Jaarsveld, M.T.; Helleman, J.; Berns, E.M.; Wiemer, E.A. Micro RNAs in ovarian cancer biology and therapy resistance. Int. J. Biochem. Cell Biol. 2010, 42, 1282-1290.
-
(2010)
Int. J. Biochem. Cell Biol
, vol.42
, pp. 1282-1290
-
-
Van Jaarsveld, M.T.1
Helleman, J.2
Berns, E.M.3
Wiemer, E.A.4
-
71
-
-
20444460289
-
Micro RNA expression profiles classify human cancers
-
Lu, J.; Getz, G.; Miska, E.A.; Alvarez-Saavedra, E.; Lamb, J.; Peck, D.; Sweet-Cordero, A.; Ebert, B.L.; Mak, R.H.; Ferrando, A.A.; et al. Micro RNA expression profiles classify human cancers. Nature 2005, 435, 834-838.
-
(2005)
Nature
, vol.435
, pp. 834-838
-
-
Lu, J.1
Getz, G.2
Miska, E.A.3
Alvarez-Saavedra, E.4
Lamb, J.5
Peck, D.6
Sweet-Cordero, A.7
Ebert, B.L.8
Mak, R.H.9
Ferrando, A.A.10
-
72
-
-
62549109089
-
Profiling of 95 microRNAs in pancreatic cancer cell lines and surgical specimens by real-time PCR analysis
-
Zhang, Y.; Li, M.; Wang, H.; Fisher, W.E.; Lin, P.H.; Yao, Q.; Chen, C. Profiling of 95 microRNAs in pancreatic cancer cell lines and surgical specimens by real-time PCR analysis. World J. Surg. 2009, 33, 698-709.
-
(2009)
World J. Surg
, vol.33
, pp. 698-709
-
-
Zhang, Y.1
Li, M.2
Wang, H.3
Fisher, W.E.4
Lin, P.H.5
Yao, Q.6
Chen, C.7
-
73
-
-
80054930119
-
MicroRNA-10b is overexpressed in pancreatic cancer, promotes its invasiveness, and correlates with a poor prognosis
-
Nakata, K.; Ohuchida, K.; Mizumoto, K.; Kayashima, T.; Ikenaga, N.; Sakai, H.; Lin, C.; Fujita, H.; Otsuka, T.; Aishima, S.; et al. MicroRNA-10b is overexpressed in pancreatic cancer, promotes its invasiveness, and correlates with a poor prognosis. Surgery 2011, 150, 916-922.
-
(2011)
Surgery
, vol.150
, pp. 916-922
-
-
Nakata, K.1
Ohuchida, K.2
Mizumoto, K.3
Kayashima, T.4
Ikenaga, N.5
Sakai, H.6
Lin, C.7
Fujita, H.8
Otsuka, T.9
Aishima, S.10
-
74
-
-
75149146772
-
A link between miR-100 and FRAP1/mTOR in clear cell ovarian cancer
-
Nagaraja, A.K.; Creighton, C.J.; Yu, Z.; Zhu, H.; Gunaratne, P.H.; Reid, J.G.; Olokpa, E.; Itamochi, H.; Ueno, N.T.; Hawkins, S.M.; et al. A link between miR-100 and FRAP1/mTOR in clear cell ovarian cancer. Mol. Endocrinol. 2010, 24, 447-463.
-
(2010)
Mol. Endocrinol
, vol.24
, pp. 447-463
-
-
Nagaraja, A.K.1
Creighton, C.J.2
Yu, Z.3
Zhu, H.4
Gunaratne, P.H.5
Reid, J.G.6
Olokpa, E.7
Itamochi, H.8
Ueno, N.T.9
Hawkins, S.M.10
-
75
-
-
70350536585
-
Distinct microRNA alterations characterize high- and low-grade bladder cancer
-
Catto, J.W.; Miah, S.; Owen, H.C.; Bryant, H.; Myers, K.; Dudziec, E.; Larre, S.; Milo, M.; Rehman, I.; Rosario, D.J.; et al. Distinct microRNA alterations characterize high- and low-grade bladder cancer. Cancer Res. 2009, 69, 8472-8481.
-
(2009)
Cancer Res
, vol.69
, pp. 8472-8481
-
-
Catto, J.W.1
Miah, S.2
Owen, H.C.3
Bryant, H.4
Myers, K.5
Dudziec, E.6
Larre, S.7
Milo, M.8
Rehman, I.9
Rosario, D.J.10
-
76
-
-
72549110532
-
A microRNA expression ratio defining the invasive phenotype in bladder tumors
-
Neely, L.A.; Rieger-Christ, K.M.; Neto, B.S.; Eroshkin, A.; Garver, J.; Patel, S.; Phung, N.A.; McLaughlin, S.; Libertino, J.A.; Whitney, D.; et al. A microRNA expression ratio defining the invasive phenotype in bladder tumors. Urol. Oncol. 2010, 28, 39-48.
-
(2010)
Urol. Oncol
, vol.28
, pp. 39-48
-
-
Neely, L.A.1
Rieger-Christ, K.M.2
Neto, B.S.3
Eroshkin, A.4
Garver, J.5
Patel, S.6
Phung, N.A.7
McLaughlin, S.8
Libertino, J.A.9
Whitney, D.10
-
77
-
-
84860389328
-
Expression of microRNA and their gene targets are dysregulated in preinvasive breast cancer
-
doi:10.1186/bcr2839
-
Hannafon, B.N.; Sebastiani, P.; de las Morenas, A.; Lu, J.; Rosenberg, C.L. Expression of microRNA and their gene targets are dysregulated in preinvasive breast cancer. Breast Cancer Res. 2011, 13, doi:10.1186/bcr2839.
-
(2011)
Breast Cancer Res
, vol.13
-
-
Hannafon, B.N.1
Sebastiani, P.2
De Las Morenas, A.3
Lu, J.4
Rosenberg, C.L.5
-
78
-
-
33644819964
-
Unique micro RNA molecular profiles in lung cancer diagnosis and prognosis
-
Yanaihara, N.; Caplen, N.; Bowman, E.; Seike, M.; Kumamoto, K.; Yi, M.; Stephens, R.M.; Okamoto, A.; Yokota, J.; Tanaka, T.; et al. Unique microRNA molecular profiles in lung cancer diagnosis and prognosis. Cancer Cell 2006, 9, 189-198.
-
(2006)
Cancer Cell
, vol.9
, pp. 189-198
-
-
Yanaihara, N.1
Caplen, N.2
Bowman, E.3
Seike, M.4
Kumamoto, K.5
Yi, M.6
Stephens, R.M.7
Okamoto, A.8
Yokota, J.9
Tanaka, T.10
-
79
-
-
54249136806
-
MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells
-
Papagiannakopoulos, T.; Shapiro, A.; Kosik, K.S. MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells. Cancer Res. 2008, 68, 8164-8172.
-
(2008)
Cancer Res
, vol.68
, pp. 8164-8172
-
-
Papagiannakopoulos, T.1
Shapiro, A.2
Kosik, K.S.3
-
80
-
-
38849107424
-
The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis
-
Huang, Q.; Gumireddy, K.; Schrier, M.; le Sage, C.; Nagel, R.; Nair, S.; Egan, D.A.; Li, A.; Huang, G.; Klein-Szanto, A.J.; et al. The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis. Nat. Cell Biol. 2008, 10, 202-210.
-
(2008)
Nat. Cell Biol
, vol.10
, pp. 202-210
-
-
Huang, Q.1
Gumireddy, K.2
Schrier, M.3
Le Sage, C.4
Nagel, R.5
Nair, S.6
Egan, D.A.7
Li, A.8
Huang, G.9
Klein-Szanto, A.J.10
-
81
-
-
33847763576
-
Genetic unmasking of an epigenetically silenced microRNA in human cancer cells
-
Lujambio, A.; Ropero, S.; Ballestar, E.; Fraga, M.F.; Cerrato, C.; Setien, F.; Casado, S.; Suarez-Gauthier, A.; Sanchez-Cespedes, M.; Git, A.; et al. Genetic unmasking of an epigenetically silenced microRNA in human cancer cells. Cancer Res. 2007, 67, 1424-1429.
-
(2007)
Cancer Res
, vol.67
, pp. 1424-1429
-
-
Lujambio, A.1
Ropero, S.2
Ballestar, E.3
Fraga, M.F.4
Cerrato, C.5
Setien, F.6
Casado, S.7
Suarez-Gauthier, A.8
Sanchez-Cespedes, M.9
Git, A.10
-
82
-
-
84871282536
-
The significance of epigenetic alterations in lung carcinogenesis
-
Brzezianska, E.; Dutkowska, A.; Antczak, A. The significance of epigenetic alterations in lung carcinogenesis. Mol. Biol. Rep. 2013, 40, 309-325.
-
(2013)
Mol. Biol. Rep
, vol.40
, pp. 309-325
-
-
Brzezianska, E.1
Dutkowska, A.2
Antczak, A.3
-
83
-
-
33745700209
-
Sequence variations of micro RNAs in human cancer: Alterations in predicted secondary structure do not affect processing
-
Diederichs, S.; Haber, D.A. Sequence variations of micro RNAs in human cancer: Alterations in predicted secondary structure do not affect processing. Cancer Res. 2006, 66, 6097-6104.
-
(2006)
Cancer Res
, vol.66
, pp. 6097-6104
-
-
Diederichs, S.1
Haber, D.A.2
-
84
-
-
84878108145
-
EGFR modulates microRNA maturation in response to hypoxia through phosphorylation of AGO2
-
Shen, J.; Xia, W.; Khotskaya, Y.B.; Huo, L.; Nakanishi, K.; Lim, S.O.; Du, Y.; Wang, Y.; Chang, W.C.; Chen, C.H.; et al. EGFR modulates microRNA maturation in response to hypoxia through phosphorylation of AGO2. Nature 2013, 497, 383-387.
-
(2013)
Nature
, vol.497
, pp. 383-387
-
-
Shen, J.1
Xia, W.2
Khotskaya, Y.B.3
Huo, L.4
Nakanishi, K.5
Lim, S.O.6
Du, Y.7
Wang, Y.8
Chang, W.C.9
Chen, C.H.10
-
85
-
-
84880255880
-
Hypoxia regulates FGFR3 expression via HIF-1α and miR-100 and contributes to cell survival in non-muscle invasive bladder cancer
-
Blick, C.; Ramachandran, A.; Wigfield, S.; McCormick, R.; Jubb, A.; Buffa, F.M.; Turley, H.; Knowles, M.A.; Cranston, D.; Catto, J.; et al. Hypoxia regulates FGFR3 expression via HIF-1α and miR-100 and contributes to cell survival in non-muscle invasive bladder cancer. Br. J. Cancer 2013, 109, 50-59.
-
(2013)
Br. J. Cancer
, vol.109
, pp. 50-59
-
-
Blick, C.1
Ramachandran, A.2
Wigfield, S.3
McCormick, R.4
Jubb, A.5
Buffa, F.M.6
Turley, H.7
Knowles, M.A.8
Cranston, D.9
Catto, J.10
-
86
-
-
0036595629
-
Epithelial-mesenchymal transitions in tumour progression
-
Thiery, J.P. Epithelial-mesenchymal transitions in tumour progression. Nat. Rev. Cancer 2002, 2, 442-454.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 442-454
-
-
Thiery, J.P.1
-
87
-
-
75649088874
-
Mechanisms of the epithelial-mesenchymal transition by TGF-β
-
Wendt, M.K.; Allington, T.M.; Schiemann, W.P. Mechanisms of the epithelial-mesenchymal transition by TGF-β. Future Oncol. 2009, 5, 1145-1168.
-
(2009)
Future Oncol
, vol.5
, pp. 1145-1168
-
-
Wendt, M.K.1
Allington, T.M.2
Schiemann, W.P.3
-
88
-
-
0034723255
-
Methylation patterns of the E-cadherin 5' CpG island are unstable and reflect the dynamic, heterogeneous loss of E-cadherin expression during metastatic progression
-
Graff, J.R.; Gabrielson, E.; Fujii, H.; Baylin, S.B.; Herman, J.G. Methylation patterns of the E-cadherin 5' CpG island are unstable and reflect the dynamic, heterogeneous loss of E-cadherin expression during metastatic progression. J. Biol. Chem. 2000, 275, 2727-2732.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 2727-2732
-
-
Graff, J.R.1
Gabrielson, E.2
Fujii, H.3
Baylin, S.B.4
Herman, J.G.5
-
89
-
-
33644834687
-
E-cadherin transcriptional downregulation by promoter methylation but not mutation is related to epithelial-to-mesenchymal transition in breast cancer cell lines
-
Lombaerts, M.; Van Wezel, T.; Philippo, K.; Dierssen, J.W.; Zimmerman, R.M.; Oosting, J.; Van Eijk, R.; Eilers, P.H.; Van de Water, B.; Cornelisse, C.J.; et al. E-cadherin transcriptional downregulation by promoter methylation but not mutation is related to epithelial-to-mesenchymal transition in breast cancer cell lines. Br. J. Cancer 2006, 94, 661-671.
-
(2006)
Br. J. Cancer
, vol.94
, pp. 661-671
-
-
Lombaerts, M.1
Van Wezel, T.2
Philippo, K.3
Dierssen, J.W.4
Zimmerman, R.M.5
Oosting, J.6
Van Eijk, R.7
Eilers, P.H.8
De Van Water, B.9
Cornelisse, C.J.10
-
90
-
-
0034662645
-
Aberrant methylation of the estrogen receptor and E-cadherin 5' CpG islands increases with malignant progression in human breast cancer
-
Nass, S.J.; Herman, J.G.; Gabrielson, E.; Iversen, P.W.; Parl, F.F.; Davidson, N.E.; Graff, J.R. Aberrant methylation of the estrogen receptor and E-cadherin 5' CpG islands increases with malignant progression in human breast cancer. Cancer Res. 2000, 60, 4346-4348.
-
(2000)
Cancer Res
, vol.60
, pp. 4346-4348
-
-
Nass, S.J.1
Herman, J.G.2
Gabrielson, E.3
Iversen, P.W.4
Parl, F.F.5
Davidson, N.E.6
Graff, J.R.7
-
91
-
-
78649987710
-
Transforming growth factor-β-induced epithelial-mesenchymal transition facilitates epidermal growth factor-dependent breast cancer progression
-
Wendt, M.K.; Smith, J.A.; Schiemann, W.P. Transforming growth factor-β-induced epithelial-mesenchymal transition facilitates epidermal growth factor-dependent breast cancer progression. Oncogene 2010, 29, 6485-6498.
-
(2010)
Oncogene
, vol.29
, pp. 6485-6498
-
-
Wendt, M.K.1
Smith, J.A.2
Schiemann, W.P.3
-
92
-
-
38549159585
-
The selectin-selectin ligand axis in tumor progression
-
Witz, I.P. The selectin-selectin ligand axis in tumor progression. Cancer Metastasis Rev. 2008, 27, 19-30.
-
(2008)
Cancer Metastasis Rev
, vol.27
, pp. 19-30
-
-
Witz, I.P.1
-
93
-
-
60849107267
-
The role of cell adhesion molecules in the progression of colorectal cancer and the development of liver metastasis
-
Paschos, K.A.; Canovas, D.; Bird, N.C. The role of cell adhesion molecules in the progression of colorectal cancer and the development of liver metastasis. Cell. Signal. 2009, 21, 665-674.
-
(2009)
Cell. Signal
, vol.21
, pp. 665-674
-
-
Paschos, K.A.1
Canovas, D.2
Bird, N.C.3
-
94
-
-
77956614939
-
Selectins promote tumor metastasis
-
Laubli, H.; Borsig, L. Selectins promote tumor metastasis. Semin. Cancer Biol. 2010, 20, 169-177.
-
(2010)
Semin. Cancer Biol
, vol.20
, pp. 169-177
-
-
Laubli, H.1
Borsig, L.2
-
95
-
-
72949119124
-
Integrins in cancer: Biological implications and therapeutic opportunities
-
Desgrosellier, J.S.; Cheresh, D.A. Integrins in cancer: Biological implications and therapeutic opportunities. Nat. Rev. Cancer 2010, 10, 9-22.
-
(2010)
Nat. Rev. Cancer
, vol.10
, pp. 9-22
-
-
Desgrosellier, J.S.1
Cheresh, D.A.2
-
96
-
-
84858309804
-
Cancer cell adhesion and metastasis: Selectins, integrins, and the inhibitory potential of heparins
-
Bendas, G.; Borsig, L. Cancer cell adhesion and metastasis: Selectins, integrins, and the inhibitory potential of heparins. Int. J. Cell Biol. 2012, 2012, 6767311-67673110.
-
(2012)
Int. J. Cell Biol
, vol.2012
, pp. 6767311-67673110
-
-
Bendas, G.1
Borsig, L.2
-
97
-
-
51049119424
-
Inhibition of metastatic outgrowth from single dormant tumor cells by targeting the cytoskeleton
-
Barkan, D.; Kleinman, H.; Simmons, J.L.; Asmussen, H.; Kamaraju, A.K.; Hoenorhoff, M.J.; Liu, Z.Y.; Costes, S.V.; Cho, E.H.; Lockett, S.; et al. Inhibition of metastatic outgrowth from single dormant tumor cells by targeting the cytoskeleton. Cancer Res. 2008, 68, 6241-6250.
-
(2008)
Cancer Res
, vol.68
, pp. 6241-6250
-
-
Barkan, D.1
Kleinman, H.2
Simmons, J.L.3
Asmussen, H.4
Kamaraju, A.K.5
Hoenorhoff, M.J.6
Liu, Z.Y.7
Costes, S.V.8
Cho, E.H.9
Lockett, S.10
-
98
-
-
67649849871
-
Integrin β1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs
-
Shibue, T.; Weinberg, R.A. Integrin β1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs. Proc. Natl. Acad. Sci. USA 2009, 106, 10290-10295.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 10290-10295
-
-
Shibue, T.1
Weinberg, R.A.2
-
99
-
-
0035861541
-
Integrin β1 signaling is necessary for transforming growth factor-β activation of p38MAPK and epithelial plasticity
-
Bhowmick, N.A.; Zent, R.; Ghiassi, M.; McDonnell, M.; Moses, H.L. Integrin β1 signaling is necessary for transforming growth factor-β activation of p38MAPK and epithelial plasticity. J. Biol. Chem. 2001, 276, 46707-46713.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 46707-46713
-
-
Bhowmick, N.A.1
Zent, R.2
Ghiassi, M.3
McDonnell, M.4
Moses, H.L.5
-
100
-
-
33747086130
-
β3 integrin and Src facilitate transforming growth factor-β mediated induction of epithelial-mesenchymal transition in mammary epithelial cells
-
Galliher, A.J.; Schiemann, W.P. β3 integrin and Src facilitate transforming growth factor-β mediated induction of epithelial-mesenchymal transition in mammary epithelial cells. Breast Cancer Res. 2006, 8, R421-R4216.
-
(2006)
Breast Cancer Res
, vol.8
-
-
Galliher, A.J.1
Schiemann, W.P.2
-
101
-
-
71749100944
-
Therapeutic targeting of the focal adhesion complex prevents oncogenic TGF-β signaling and metastasis
-
Wendt, M.K.; Schiemann, W.P. Therapeutic targeting of the focal adhesion complex prevents oncogenic TGF-β signaling and metastasis. Breast Cancer Res. 2009, 11, R681-R6816.
-
(2009)
Breast Cancer Res
, vol.11
-
-
Wendt, M.K.1
Schiemann, W.P.2
-
102
-
-
0036020979
-
The role of Aktand RAFTK in β1 integrin mediated survival of precursor B-acute lymphoblastic leukemia cells
-
Sarkar, S.; Svoboda, M.; de Beaumont, R.; Freedman, A.S. The role of Aktand RAFTK in β1 integrin mediated survival of precursor B-acute lymphoblastic leukemia cells. Leuk. Lymphoma 2002, 43, 1663-1671.
-
(2002)
Leuk. Lymphoma
, vol.43
, pp. 1663-1671
-
-
Sarkar, S.1
Svoboda, M.2
de Beaumont, R.3
Freedman, A.S.4
-
103
-
-
0032426644
-
Tyrosine phosphorylation and translocation of LAT in platelets
-
Sarkar, S. Tyrosine phosphorylation and translocation of LAT in platelets. FEBS Lett. 1998, 441, 357-360.
-
(1998)
FEBS Lett
, vol.441
, pp. 357-360
-
-
Sarkar, S.1
-
104
-
-
0033559816
-
Activation of integrin-β3-associated syk in platelets
-
Sarkar, S.; Rooney, M.M.; Lord, S.T. Activation of integrin-β3-associated syk in platelets. Biochem. J. 1999, 338, 677-680.
-
(1999)
Biochem. J
, vol.338
, pp. 677-680
-
-
Sarkar, S.1
Rooney, M.M.2
Lord, S.T.3
-
105
-
-
33746849303
-
Co-opted integrin signaling in ErbB2-induced mammary tumor progression
-
Carraway, K.L., 3rd; Sweeney, C. Co-opted integrin signaling in ErbB2-induced mammary tumor progression. Cancer Cell 2006, 10, 93-95.
-
(2006)
Cancer Cell
, vol.10
, pp. 93-95
-
-
Carraway III, K.L.1
Sweeney, C.2
-
106
-
-
84880011146
-
In vivo RNAi screening identifies a leukemia-specific dependence on integrin β 3 signaling
-
Miller, P.G.; Al-Shahrour, F.; Hartwell, K.A.; Chu, L.P.; Jaras, M.; Puram, R.V.; Puissant, A.; Callahan, K.P.; Ashton, J.; McConkey, M.E.; et al. In vivo RNAi screening identifies a leukemia-specific dependence on integrin β 3 signaling. Cancer Cell 2013, 24, 45-58.
-
(2013)
Cancer Cell
, vol.24
, pp. 45-58
-
-
Miller, P.G.1
Al-Shahrour, F.2
Hartwell, K.A.3
Chu, L.P.4
Jaras, M.5
Puram, R.V.6
Puissant, A.7
Callahan, K.P.8
Ashton, J.9
McConkey, M.E.10
-
107
-
-
2442652651
-
Aberrant methylation of integrin α4 gene in human gastric cancer cells
-
Park, J.; Song, S.H.; Kim, T.Y.; Choi, M.C.; Jong, H.S.; Kim, T.Y.; Lee, J.W.; Kim, N.K.; Kim, W.H.; Bang, Y.J. Aberrant methylation of integrin α4 gene in human gastric cancer cells. Oncogene 2004, 23, 3474-3480.
-
(2004)
Oncogene
, vol.23
, pp. 3474-3480
-
-
Park, J.1
Song, S.H.2
Kim, T.Y.3
Choi, M.C.4
Jong, H.S.5
Kim, T.Y.6
Lee, J.W.7
Kim, N.K.8
Kim, W.H.9
Bang, Y.J.10
-
108
-
-
33947711768
-
Nidogen 1 and 2 gene promoters are aberrantly methylated in human gastrointestinal cancer
-
Ulazzi, L.; Sabbioni, S.; Miotto, E.; Veronese, A.; Angusti, A.; Gafa, R.; Manfredini, S.; Farinati, F.; Sasaki, T.; Lanza, G.; et al. Nidogen 1 and 2 gene promoters are aberrantly methylated in human gastrointestinal cancer. Mol. Cancer 2007, 6, 17:1-17:9.
-
(2007)
Mol. Cancer
, vol.6
, Issue.1-17
, pp. 9
-
-
Ulazzi, L.1
Sabbioni, S.2
Miotto, E.3
Veronese, A.4
Angusti, A.5
Gafa, R.6
Manfredini, S.7
Farinati, F.8
Sasaki, T.9
Lanza, G.10
-
109
-
-
18444383363
-
Expression, regulation, and function of αV integrins in hepatocellular carcinoma: An in vivo and in vitro study
-
Nejjari, M.; Hafdi, Z.; Gouysse, G.; Fiorentino, M.; Beatrix, O.; Dumortier, J.; Pourreyron, C.; Barozzi, C.; D'Errico, A.; Grigioni, W.F.; et al. Expression, regulation, and function of αV integrins in hepatocellular carcinoma: An in vivo and in vitro study. Hepatology 2002, 36, 418-426.
-
(2002)
Hepatology
, vol.36
, pp. 418-426
-
-
Nejjari, M.1
Hafdi, Z.2
Gouysse, G.3
Fiorentino, M.4
Beatrix, O.5
Dumortier, J.6
Pourreyron, C.7
Barozzi, C.8
Derrico, A.9
Grigioni, W.F.10
-
110
-
-
33749017931
-
Cysteine cathepsins: Multifunctional enzymes in cancer
-
Mohamed, M.M.; Sloane, B.F. Cysteine cathepsins: Multifunctional enzymes in cancer. Nat. Rev. Cancer 2006, 6, 764-775.
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 764-775
-
-
Mohamed, M.M.1
Sloane, B.F.2
-
111
-
-
33846643454
-
Cysteine cathepsins and the cutting edge of cancer invasion
-
Gocheva, V.; Joyce, J.A. Cysteine cathepsins and the cutting edge of cancer invasion. Cell Cycle 2007, 6, 60-64.
-
(2007)
Cell Cycle
, vol.6
, pp. 60-64
-
-
Gocheva, V.1
Joyce, J.A.2
-
112
-
-
33748932676
-
Urokinase-receptor (u-PAR): An essential player in multiple games of cancer: A review on its role in tumor progression, invasion, metastasis, proliferation/dormancy, clinical outcome and minimal residual disease
-
Laufs, S.; Schumacher, J.; Allgayer, H. Urokinase-receptor (u-PAR): An essential player in multiple games of cancer: A review on its role in tumor progression, invasion, metastasis, proliferation/dormancy, clinical outcome and minimal residual disease. Cell Cycle 2006, 5, 1760-1771.
-
(2006)
Cell Cycle
, vol.5
, pp. 1760-1771
-
-
Laufs, S.1
Schumacher, J.2
Allgayer, H.3
-
113
-
-
0036512208
-
New functions for the matrix metalloproteinases in cancer progression
-
Egeblad, M.; Werb, Z. New functions for the matrix metalloproteinases in cancer progression. Nat. Rev. Cancer 2002, 2, 161-174.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 161-174
-
-
Egeblad, M.1
Werb, Z.2
-
114
-
-
0036995757
-
Matrix metalloproteinases in tumor-host cell communication
-
Lynch, C.C.; Matrisian, L.M. Matrix metalloproteinases in tumor-host cell communication. Differentiation 2002, 70, 561-573.
-
(2002)
Differentiation
, vol.70
, pp. 561-573
-
-
Lynch, C.C.1
Matrisian, L.M.2
-
115
-
-
34250769385
-
Posttranslational truncation of E-cadherin and significance for tumour progression
-
Masterson, J.; O'Dea, S. Posttranslational truncation of E-cadherin and significance for tumour progression. Cells Tissues Organs 2007, 185, 175-179.
-
(2007)
Cells Tissues Organs
, vol.185
, pp. 175-179
-
-
Masterson, J.1
O'Dea, S.2
-
116
-
-
0037052641
-
Matrix metalloproteinases in cancer: Prognostic markers and therapeutic targets
-
Vihinen, P.; Kahari, V.M. Matrix metalloproteinases in cancer: Prognostic markers and therapeutic targets. Int. J. Cancer 2002, 99, 157-166.
-
(2002)
Int. J. Cancer
, vol.99
, pp. 157-166
-
-
Vihinen, P.1
Kahari, V.M.2
-
117
-
-
0028603343
-
TGF-β induced transdifferentiation of mammary epithelial cells to mesenchymal cells: Involvement of type I receptors
-
Miettinen, P.J.; Ebner, R.; Lopez, A.R.; Derynck, R. TGF-β induced transdifferentiation of mammary epithelial cells to mesenchymal cells: Involvement of type I receptors. J. Cell Biol. 1994, 127, 2021-2036.
-
(1994)
J. Cell Biol
, vol.127
, pp. 2021-2036
-
-
Miettinen, P.J.1
Ebner, R.2
Lopez, A.R.3
Derynck, R.4
-
118
-
-
43049165453
-
The epithelial-mesenchymal transition generates cells with properties of stem cells
-
Mani, S.A.; Guo, W.; Liao, M.J.; Eaton, E.N.; Ayyanan, A.; Zhou, A.Y.; Brooks, M.; Reinhard, F.; Zhang, C.C.; Shipitsin, M.; et al. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 2008, 133, 704-715.
-
(2008)
Cell
, vol.133
, pp. 704-715
-
-
Mani, S.A.1
Guo, W.2
Liao, M.J.3
Eaton, E.N.4
Ayyanan, A.5
Zhou, A.Y.6
Brooks, M.7
Reinhard, F.8
Zhang, C.C.9
Shipitsin, M.10
-
119
-
-
77955811853
-
Epithelial-mesenchymal transition-derived cells exhibit multilineage differentiation potential similar to mesenchymal stem cells
-
Battula, V.L.; Evans, K.W.; Hollier, B.G.; Shi, Y.; Marini, F.C.; Ayyanan, A.; Wang, R.Y.; Brisken, C.; Guerra, R.; Andreeff, M.; et al. Epithelial-mesenchymal transition-derived cells exhibit multilineage differentiation potential similar to mesenchymal stem cells. Stem Cells 2010, 28, 1435-1445.
-
(2010)
Stem Cells
, vol.28
, pp. 1435-1445
-
-
Battula, V.L.1
Evans, K.W.2
Hollier, B.G.3
Shi, Y.4
Marini, F.C.5
Ayyanan, A.6
Wang, R.Y.7
Brisken, C.8
Guerra, R.9
Andreeff, M.10
-
120
-
-
77957262381
-
Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes
-
Taube, J.H.; Herschkowitz, J.I.; Komurov, K.; Zhou, A.Y.; Gupta, S.; Yang, J.; Hartwell, K.; Onder, T.T.; Gupta, P.B.; Evans, K.W.; et al. Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes. Proc. Natl. Acad. Sci. USA 2010, 107, 15449-15454.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 15449-15454
-
-
Taube, J.H.1
Herschkowitz, J.I.2
Komurov, K.3
Zhou, A.Y.4
Gupta, S.5
Yang, J.6
Hartwell, K.7
Onder, T.T.8
Gupta, P.B.9
Evans, K.W.10
-
121
-
-
4043052971
-
Epithelial-mesenchymal transitions: Twist in development and metastasis
-
Kang, Y.; Massague, J. Epithelial-mesenchymal transitions: Twist in development and metastasis. Cell 2004, 118, 277-279.
-
(2004)
Cell
, vol.118
, pp. 277-279
-
-
Kang, Y.1
Massague, J.2
-
122
-
-
34548856802
-
Isolation and molecular profiling of bone marrow micrometastases identifies TWIST1 as a marker of early tumor relapse in breast cancer patients
-
Watson, M.A.; Ylagan, L.R.; Trinkaus, K.M.; Gillanders, W.E.; Naughton, M.J.; Weilbaecher, K.N.; Fleming, T.P.; Aft, R.L. Isolation and molecular profiling of bone marrow micrometastases identifies TWIST1 as a marker of early tumor relapse in breast cancer patients. Clin. Cancer Res. 2007, 13, 5001-5009.
-
(2007)
Clin. Cancer Res
, vol.13
, pp. 5001-5009
-
-
Watson, M.A.1
Ylagan, L.R.2
Trinkaus, K.M.3
Gillanders, W.E.4
Naughton, M.J.5
Weilbaecher, K.N.6
Fleming, T.P.7
Aft, R.L.8
-
123
-
-
33947192053
-
Twist transcriptionally up-regulates AKT2 in breast cancer cells leading to increased migration, invasion, and resistance to paclitaxel
-
Cheng, G.Z.; Chan, J.; Wang, Q.; Zhang, W.; Sun, C.D.; Wang, L.H. Twist transcriptionally up-regulates AKT2 in breast cancer cells leading to increased migration, invasion, and resistance to paclitaxel. Cancer Res. 2007, 67, 1979-1987.
-
(2007)
Cancer Res
, vol.67
, pp. 1979-1987
-
-
Cheng, G.Z.1
Chan, J.2
Wang, Q.3
Zhang, W.4
Sun, C.D.5
Wang, L.H.6
-
124
-
-
0035020950
-
Phosphoinositide 3-kinase signalling pathways
-
Cantrell, D.A. Phosphoinositide 3-kinase signalling pathways. J. Cell Sci. 2001, 114, 1439-1445.
-
(2001)
J. Cell Sci
, vol.114
, pp. 1439-1445
-
-
Cantrell, D.A.1
-
125
-
-
16644393213
-
The PIK3CA gene is mutated with high frequency in human breast cancers
-
Bachman, K.E.; Argani, P.; Samuels, Y.; Silliman, N.; Ptak, J.; Szabo, S.; Konishi, H.; Karakas, B.; Blair, B.G.; Lin, C.; et al. The PIK3CA gene is mutated with high frequency in human breast cancers. Cancer Biol. Ther. 2004, 3, 772-775.
-
(2004)
Cancer Biol. Ther
, vol.3
, pp. 772-775
-
-
Bachman, K.E.1
Argani, P.2
Samuels, Y.3
Silliman, N.4
Ptak, J.5
Szabo, S.6
Konishi, H.7
Karakas, B.8
Blair, B.G.9
Lin, C.10
-
126
-
-
1042292609
-
Akt2: A role in breast cancer metastasis
-
Chau, N.M.; Ashcroft, M. Akt2: A role in breast cancer metastasis. Breast Cancer Res. 2004, 6, 55-57.
-
(2004)
Breast Cancer Res
, vol.6
, pp. 55-57
-
-
Chau, N.M.1
Ashcroft, M.2
-
127
-
-
33747610198
-
Differential roles of phosphoinositide-dependent protein kinase-1 and akt1 expression and phosphorylation in breast cancer cell resistance to paclitaxel, doxorubicin, and gemcitabine
-
Liang, K.; Lu, Y.; Li, X.; Zeng, X.; Glazer, R.I.; Mills, G.B.; Fan, Z. Differential roles of phosphoinositide-dependent protein kinase-1 and akt1 expression and phosphorylation in breast cancer cell resistance to paclitaxel, doxorubicin, and gemcitabine. Mol. Pharmacol. 2006, 70, 1045-1052.
-
(2006)
Mol. Pharmacol
, vol.70
, pp. 1045-1052
-
-
Liang, K.1
Lu, Y.2
Li, X.3
Zeng, X.4
Glazer, R.I.5
Mills, G.B.6
Fan, Z.7
-
128
-
-
65349147075
-
Repertoire of microRNAs in epithelial ovarian cancer as determined by next generation sequencing of small RNA cDNA libraries
-
Wyman, S.K.; Parkin, R.K.; Mitchell, P.S.; Fritz, B.R.; O'Briant, K.; Godwin, A.K.; Urban, N.; Drescher, C.W.; Knudsen, B.S.; Tewari, M. Repertoire of microRNAs in epithelial ovarian cancer as determined by next generation sequencing of small RNA cDNA libraries. PLoS One 2009, 4, e5311.
-
(2009)
PLoS One
, vol.4
-
-
Wyman, S.K.1
Parkin, R.K.2
Mitchell, P.S.3
Fritz, B.R.4
O'Briant, K.5
Godwin, A.K.6
Urban, N.7
Drescher, C.W.8
Knudsen, B.S.9
Tewari, M.10
-
129
-
-
84879077809
-
Reduced expression of miR-22 in gastric cancer is related to clinicopathologic characteristics or patient prognosis
-
doi:10.1186/1746-1596-8-102
-
Wang, W.; Li, F.; Zhang, Y.; Tu, Y.; Yang, Q.; Gao, X. Reduced expression of miR-22 in gastric cancer is related to clinicopathologic characteristics or patient prognosis. Diagn. Pathol. 2013, doi:10.1186/1746-1596-8-102.
-
(2013)
Diagn. Pathol
-
-
Wang, W.1
Li, F.2
Zhang, Y.3
Tu, Y.4
Yang, Q.5
Gao, X.6
-
130
-
-
84880570961
-
Micro RNA-antagonism regulates breast cancer stemness and metastasis via TET-family-dependent chromatin remodeling
-
Song, S.J.; Poliseno, L.; Song, M.S.; Ala, U.; Webster, K.; Ng, C.; Beringer, G.; Brikbak, N.J.; Yuan, X.; Cantley, L.C.; et al. Micro RNA-antagonism regulates breast cancer stemness and metastasis via TET-family-dependent chromatin remodeling. Cell 2013, 154, 311-324.
-
(2013)
Cell
, vol.154
, pp. 311-324
-
-
Song, S.J.1
Poliseno, L.2
Song, M.S.3
Ala, U.4
Webster, K.5
Ng, C.6
Beringer, G.7
Brikbak, N.J.8
Yuan, X.9
Cantley, L.C.10
-
131
-
-
84880571480
-
The oncogenic microRNA miR-22 targets the TET2 tumor suppressor to promote hematopoietic stem cell self-renewal and transformation
-
Song, S.J.; Ito, K.; Ala, U.; Kats, L.; Webster, K.; Sun, S.M.; Jongen-Lavrencic, M.; Manova-Todorova, K.; Teruya-Feldstein, J.; Avigan, D.E.; et al. The oncogenic microRNA miR-22 targets the TET2 tumor suppressor to promote hematopoietic stem cell self-renewal and transformation. Cell Stem Cell 2013, 13, 87-101.
-
(2013)
Cell Stem Cell
, vol.13
, pp. 87-101
-
-
Song, S.J.1
Ito, K.2
Ala, U.3
Kats, L.4
Webster, K.5
Sun, S.M.6
Jongen-Lavrencic, M.7
Manova-Todorova, K.8
Teruya-Feldstein, J.9
Avigan, D.E.10
-
132
-
-
38049115129
-
Endogenous human microRNAs that suppress breast cancer metastasis
-
Tavazoie, S.F.; Alarcon, C.; Oskarsson, T.; Padua, D.; Wang, Q.; Bos, P.D.; Gerald, W.L.; Massague, J. Endogenous human microRNAs that suppress breast cancer metastasis. Nature 2008, 451, 147-152.
-
(2008)
Nature
, vol.451
, pp. 147-152
-
-
Tavazoie, S.F.1
Alarcon, C.2
Oskarsson, T.3
Padua, D.4
Wang, Q.5
Bos, P.D.6
Gerald, W.L.7
Massague, J.8
-
133
-
-
70149100658
-
Chromobox protein homologue 7 protein, with decreased expression in human carcinomas, positively regulates E-cadherin expression by interacting with the histone deacetylase 2 protein
-
Federico, A.; Pallante, P.; Bianco, M.; Ferraro, A.; Esposito, F.; Monti, M.; Cozzolino, M.; Keller, S.; Fedele, M.; Leone, V.; et al. Chromobox protein homologue 7 protein, with decreased expression in human carcinomas, positively regulates E-cadherin expression by interacting with the histone deacetylase 2 protein. Cancer Res. 2009, 69, 7079-7087.
-
(2009)
Cancer Res
, vol.69
, pp. 7079-7087
-
-
Federico, A.1
Pallante, P.2
Bianco, M.3
Ferraro, A.4
Esposito, F.5
Monti, M.6
Cozzolino, M.7
Keller, S.8
Fedele, M.9
Leone, V.10
-
134
-
-
84871003536
-
MiR-205 regulates basement membrane deposition in human prostate: Implications for cancer development
-
Gandellini, P.; Profumo, V.; Casamichele, A.; Fenderico, N.; Borrelli, S.; Petrovich, G.; Santilli, G.; Callari, M.; Colecchia, M.; Pozzi, S.; et al. MiR-205 regulates basement membrane deposition in human prostate: Implications for cancer development. Cell Death Differ. 2012, 19, 1750-1760.
-
(2012)
Cell Death Differ
, vol.19
, pp. 1750-1760
-
-
Gandellini, P.1
Profumo, V.2
Casamichele, A.3
Fenderico, N.4
Borrelli, S.5
Petrovich, G.6
Santilli, G.7
Callari, M.8
Colecchia, M.9
Pozzi, S.10
-
135
-
-
79953147370
-
A perspective on cancer cell metastasis
-
Chaffer, C.L.; Weinberg, R.A. A perspective on cancer cell metastasis. Science 2011, 331, 1559-1564.
-
(2011)
Science
, vol.331
, pp. 1559-1564
-
-
Chaffer, C.L.1
Weinberg, R.A.2
-
136
-
-
84867578091
-
EMT-activating transcription factors in cancer: Beyond EMT and tumor invasiveness
-
Sanchez-Tillo, E.; Liu, Y.; de Barrios, O.; Siles, L.; Fanlo, L.; Cuatrecasas, M.; Darling, D.S.; Dean, D.C.; Castells, A.; Postigo, A. EMT-activating transcription factors in cancer: Beyond EMT and tumor invasiveness. Cell. Mol. Life Sci. 2012, 69, 3429-3456.
-
(2012)
Cell. Mol. Life Sci
, vol.69
, pp. 3429-3456
-
-
Sanchez-Tillo, E.1
Liu, Y.2
de Barrios, O.3
Siles, L.4
Fanlo, L.5
Cuatrecasas, M.6
Darling, D.S.7
Dean, D.C.8
Castells, A.9
Postigo, A.10
-
137
-
-
84877928478
-
Regulation of epithelial-mesenchymal and mesenchymal-epithelial transitions by microRNAs
-
Lamouille, S.; Subramanyam, D.; Blelloch, R.; Derynck, R. Regulation of epithelial-mesenchymal and mesenchymal-epithelial transitions by microRNAs. Curr. Opin. Cell Biol. 2013, 25, 200-207.
-
(2013)
Curr. Opin. Cell Biol
, vol.25
, pp. 200-207
-
-
Lamouille, S.1
Subramanyam, D.2
Blelloch, R.3
Derynck, R.4
-
138
-
-
84881048357
-
TGF-β1 regulates cell fate during epithelial-mesenchymal transition by upregulating survivin
-
doi:10.1038/cddis.2013.244
-
Lee, J.; Choi, J.H.; Joo, C.K. TGF-β1 regulates cell fate during epithelial-mesenchymal transition by upregulating survivin. Cell Death Dis. 2013, doi:10.1038/cddis.2013.244.
-
(2013)
Cell Death Dis
-
-
Lee, J.1
Choi, J.H.2
Joo, C.K.3
-
139
-
-
78651515618
-
Epigenetic suppression of the TGF-β pathway revealed by transcriptome profiling in ovarian cancer
-
Matsumura, N.; Huang, Z.; Mori, S.; Baba, T.; Fujii, S.; Konishi, I.; Iversen, E.S.; Berchuck, A.; Murphy, S.K. Epigenetic suppression of the TGF-β pathway revealed by transcriptome profiling in ovarian cancer. Genome Res. 2011, 21, 74-82.
-
(2011)
Genome Res
, vol.21
, pp. 74-82
-
-
Matsumura, N.1
Huang, Z.2
Mori, S.3
Baba, T.4
Fujii, S.5
Konishi, I.6
Iversen, E.S.7
Berchuck, A.8
Murphy, S.K.9
-
140
-
-
84862798509
-
Concordant promoter methylation of transforming growth factor-β receptor types I and II occurs early in esophageal squamous cell carcinoma
-
Dong, Z.; Guo, W.; Guo, Y.; Kuang, G.; Yang, Z. Concordant promoter methylation of transforming growth factor-β receptor types I and II occurs early in esophageal squamous cell carcinoma. Am. J. Med. Sci. 2012, 343, 375-381.
-
(2012)
Am. J. Med. Sci
, vol.343
, pp. 375-381
-
-
Dong, Z.1
Guo, W.2
Guo, Y.3
Kuang, G.4
Yang, Z.5
-
141
-
-
79951836778
-
Toligos inhibit growth and induce apoptosis in human ovarian cancer cells
-
Sarkar, S.; Faller, D.V. Toligos inhibit growth and induce apoptosis in human ovarian cancer cells. Oligonucleotides 2011, 21, 47-53.
-
(2011)
Oligonucleotides
, vol.21
, pp. 47-53
-
-
Sarkar, S.1
Faller, D.V.2
-
142
-
-
49649098602
-
Combination therapy of established cancer using a histone deacetylase inhibitor and a TRAIL receptor agonist
-
Frew, A.J.; Lindemann, R.K.; Martin, B.P.; Clarke, C.J.; Sharkey, J.; Anthony, D.A.; Banks, K.M.; Haynes, N.M.; Gangatirkar, P.; Stanley, K.; et al. Combination therapy of established cancer using a histone deacetylase inhibitor and a TRAIL receptor agonist. Proc. Natl. Acad. Sci. USA 2008, 105, 11317-11322.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 11317-11322
-
-
Frew, A.J.1
Lindemann, R.K.2
Martin, B.P.3
Clarke, C.J.4
Sharkey, J.5
Anthony, D.A.6
Banks, K.M.7
Haynes, N.M.8
Gangatirkar, P.9
Stanley, K.10
-
143
-
-
73949106115
-
Epigenetic therapies for chemoresensitization of epithelial ovarian cancer
-
Matei, D.E.; Nephew, K.P. Epigenetic therapies for chemoresensitization of epithelial ovarian cancer. Gynecol. Oncol. 2010, 116, 195-201.
-
(2010)
Gynecol. Oncol
, vol.116
, pp. 195-201
-
-
Matei, D.E.1
Nephew, K.P.2
-
144
-
-
80051644174
-
Histone deacetylase inhibitors reverse CpG methylation by regulating DNMT1 through ERK signaling
-
Sarkar, S.; Abujamra, A.L.; Loew, J.E.; Forman, L.W.; Perrine, S.P.; Faller, D.V. Histone deacetylase inhibitors reverse CpG methylation by regulating DNMT1 through ERK signaling. Anticancer Res. 2011, 31, 2723-2732.
-
(2011)
Anticancer Res
, vol.31
, pp. 2723-2732
-
-
Sarkar, S.1
Abujamra, A.L.2
Loew, J.E.3
Forman, L.W.4
Perrine, S.P.5
Faller, D.V.6
-
145
-
-
51049117752
-
Inhibition of histone deacetylases promotes ubiquitin-dependent proteasomal degradation of DNA methyltransferase 1 in human breast cancer cells
-
Zhou, Q.; Agoston, A.T.; Atadja, P.; Nelson, W.G.; Davidson, N.E. Inhibition of histone deacetylases promotes ubiquitin-dependent proteasomal degradation of DNA methyltransferase 1 in human breast cancer cells. Mol. Cancer Res. 2008, 6, 873-883.
-
(2008)
Mol. Cancer Res
, vol.6
, pp. 873-883
-
-
Zhou, Q.1
Agoston, A.T.2
Atadja, P.3
Nelson, W.G.4
Davidson, N.E.5
-
146
-
-
10744223629
-
Reactivation of the silenced and imprinted alleles of ARHI is associated with increased histone H3 acetylation and decreased histone H3 lysine 9 methylation
-
Fujii, S.; Luo, R.Z.; Yuan, J.; Kadota, M.; Oshimura, M.; Dent, S.R.; Kondo, Y.; Issa, J.P.; Bast, R.C., Jr.; Yu, Y. Reactivation of the silenced and imprinted alleles of ARHI is associated with increased histone H3 acetylation and decreased histone H3 lysine 9 methylation. Hum. Mol. Genet. 2003, 12, 1791-1800.
-
(2003)
Hum. Mol. Genet
, vol.12
, pp. 1791-1800
-
-
Fujii, S.1
Luo, R.Z.2
Yuan, J.3
Kadota, M.4
Oshimura, M.5
Dent, S.R.6
Kondo, Y.7
Issa, J.P.8
Bast Jr., R.C.9
Yu, Y.10
-
147
-
-
0024337144
-
Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer
-
Slamon, D.J.; Godolphin, W.; Jones, L.A.; Holt, J.A.; Wong, S.G.; Keith, D.E.; Levin, W.J.; Stuart, S.G.; Udove, J.; Ullrich, A.; et al. Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer. Science 1989, 244, 707-712.
-
(1989)
Science
, vol.244
, pp. 707-712
-
-
Slamon, D.J.1
Godolphin, W.2
Jones, L.A.3
Holt, J.A.4
Wong, S.G.5
Keith, D.E.6
Levin, W.J.7
Stuart, S.G.8
Udove, J.9
Ullrich, A.10
-
148
-
-
79952241034
-
Epigenetic silencing mediated through activated PI3K/AKT signaling in breast cancer
-
Zuo, T.; Liu, T.M.; Lan, X.; Weng, Y.I.; Shen, R.; Gu, F.; Huang, Y.W.; Liyanarachchi, S.; Deatherage, D.E.; Hsu, P.Y.; et al. Epigenetic silencing mediated through activated PI3K/AKT signaling in breast cancer. Cancer Res. 2011, 71, 1752-1762.
-
(2011)
Cancer Res
, vol.71
, pp. 1752-1762
-
-
Zuo, T.1
Liu, T.M.2
Lan, X.3
Weng, Y.I.4
Shen, R.5
Gu, F.6
Huang, Y.W.7
Liyanarachchi, S.8
Deatherage, D.E.9
Hsu, P.Y.10
-
149
-
-
78650981194
-
A methylation and phosphorylation switch between an adjacent lysine and serine determines human DNMT1 stability
-
Esteve, P.O.; Chang, Y.; Samaranayake, M.; Upadhyay, A.K.; Horton, J.R.; Feehery, G.R.; Cheng, X.; Pradhan, S. A methylation and phosphorylation switch between an adjacent lysine and serine determines human DNMT1 stability. Nat. Struct. Mol. Biol. 2011, 18, 42-48.
-
(2011)
Nat. Struct. Mol. Biol
, vol.18
, pp. 42-48
-
-
Esteve, P.O.1
Chang, Y.2
Samaranayake, M.3
Upadhyay, A.K.4
Horton, J.R.5
Feehery, G.R.6
Cheng, X.7
Pradhan, S.8
-
150
-
-
84880288028
-
MiR-375 is upregulated in acquired paclitaxel resistance in cervical cancer
-
Shen, Y.; Wang, P.; Li, Y.; Ye, F.; Wang, F.; Wan, X.; Cheng, X.; Lu, W.; Xie, X. MiR-375 is upregulated in acquired paclitaxel resistance in cervical cancer. Br. J. Cancer 2013, 109, 92-99.
-
(2013)
Br. J. Cancer
, vol.109
, pp. 92-99
-
-
Shen, Y.1
Wang, P.2
Li, Y.3
Ye, F.4
Wang, F.5
Wan, X.6
Cheng, X.7
Lu, W.8
Xie, X.9
-
151
-
-
56449108015
-
Role of microRNAs in drug-resistant ovarian cancer cells
-
Sorrentino, A.; Liu, C.G.; Addario, A.; Peschle, C.; Scambia, G.; Ferlini, C. Role of microRNAs in drug-resistant ovarian cancer cells. Gynecol. Oncol. 2008, 111, 478-486.
-
(2008)
Gynecol. Oncol
, vol.111
, pp. 478-486
-
-
Sorrentino, A.1
Liu, C.G.2
Addario, A.3
Peschle, C.4
Scambia, G.5
Ferlini, C.6
-
152
-
-
0023375843
-
Azacitidine: Ten years later
-
Glover, A.B.; Leyland-Jones, B.R.; Chun, H.G.; Davies, B.; Hoth, D.F. Azacitidine: Ten years later. Cancer Treat. Rep. 1987, 71, 737-746.
-
(1987)
Cancer Treat. Rep
, vol.71
, pp. 737-746
-
-
Glover, A.B.1
Leyland-Jones, B.R.2
Chun, H.G.3
Davies, B.4
Hoth, D.F.5
-
153
-
-
40849124009
-
DNA methylation markers and early recurrence in stage I lung cancer
-
Brock, M.V.; Hooker, C.M.; Ota-Machida, E.; Han, Y.; Guo, M.; Ames, S.; Glockner, S.; Piantadosi, S.; Gabrielson, E.; Pridham, G.; et al. DNA methylation markers and early recurrence in stage I lung cancer. N. Engl. J. Med. 2008, 358, 1118-1128.
-
(2008)
N. Engl. J. Med
, vol.358
, pp. 1118-1128
-
-
Brock, M.V.1
Hooker, C.M.2
Ota-Machida, E.3
Han, Y.4
Guo, M.5
Ames, S.6
Glockner, S.7
Piantadosi, S.8
Gabrielson, E.9
Pridham, G.10
-
154
-
-
84655163371
-
Combination epigenetic therapy has efficacy in patients with refractory advanced non-small cell lung cancer
-
Juergens, R.A.; Wrangle, J.; Vendetti, F.P.; Murphy, S.C.; Zhao, M.; Coleman, B.; Sebree, R.; Rodgers, K.; Hooker, C.M.; Franco, N.; et al. Combination epigenetic therapy has efficacy in patients with refractory advanced non-small cell lung cancer. Cancer Discov. 2011, 1, 598-607.
-
(2011)
Cancer Discov
, vol.1
, pp. 598-607
-
-
Juergens, R.A.1
Wrangle, J.2
Vendetti, F.P.3
Murphy, S.C.4
Zhao, M.5
Coleman, B.6
Sebree, R.7
Rodgers, K.8
Hooker, C.M.9
Franco, N.10
-
155
-
-
33747203758
-
Antileukemia activity of the combination of an anthracycline with a histone deacetylase inhibitor
-
Sanchez-Gonzalez, B.; Yang, H.; Bueso-Ramos, C.; Hoshino, K.; Quintas-Cardama, A.; Richon, V.M.; Garcia-Manero, G. Antileukemia activity of the combination of an anthracycline with a histone deacetylase inhibitor. Blood 2006, 108, 1174-1182.
-
(2006)
Blood
, vol.108
, pp. 1174-1182
-
-
Sanchez-Gonzalez, B.1
Yang, H.2
Bueso-Ramos, C.3
Hoshino, K.4
Quintas-Cardama, A.5
Richon, V.M.6
Garcia-Manero, G.7
-
156
-
-
77954325193
-
Phase I trial of low dose decitabine targeting DNA hypermethylation in patients with chronic lymphocytic leukaemia and non-Hodgkin lymphoma: Dose-limiting myelosuppression without evidence of DNA hypomethylation
-
Blum, K.A.; Liu, Z.; Lucas, D.M.; Chen, P.; Xie, Z.; Baiocchi, R.; Benson, D.M.; Devine, S.M.; Jones, J.; Andritsos, L.; et al. Phase I trial of low dose decitabine targeting DNA hypermethylation in patients with chronic lymphocytic leukaemia and non-Hodgkin lymphoma: Dose-limiting myelosuppression without evidence of DNA hypomethylation. Br. J. Haematol. 2010, 150, 189-195.
-
(2010)
Br. J. Haematol
, vol.150
, pp. 189-195
-
-
Blum, K.A.1
Liu, Z.2
Lucas, D.M.3
Chen, P.4
Xie, Z.5
Baiocchi, R.6
Benson, D.M.7
Devine, S.M.8
Jones, J.9
Andritsos, L.10
-
157
-
-
34548529948
-
Phase I study of decitabine alone or in combination with valproic acid in acute myeloid leukemia
-
Blum, W.; Klisovic, R.B.; Hackanson, B.; Liu, Z.; Liu, S.; Devine, H.; Vukosavljevic, T.; Huynh, L.; Lozanski, G.; Kefauver, C.; et al. Phase I study of decitabine alone or in combination with valproic acid in acute myeloid leukemia. J. Clin. Oncol. 2007, 25, 3884-3891.
-
(2007)
J. Clin. Oncol
, vol.25
, pp. 3884-3891
-
-
Blum, W.1
Klisovic, R.B.2
Hackanson, B.3
Liu, Z.4
Liu, S.5
Devine, H.6
Vukosavljevic, T.7
Huynh, L.8
Lozanski, G.9
Kefauver, C.10
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