Histone deacetylase inhibitors reverse CpG methylation by regulating DNMT1 through ERK signaling

Anticancer Research

Volumn 31, Issue 9, 2011, Pages 2723-2732

  Sarkar, Sibaji ^a   Abujamra, Ana L ^a   Loew, Jenny E ^a   Forman, Lora W ^a   Perrine, Susan P ^a   Faller, Douglas V ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cell cycle arrest; DNA N methyl transferase; ERK; Tumor suppressors

Indexed keywords

BUTYRIC ACID; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLIN DEPENDENT KINASE INHIBITOR 2A; DNA METHYLTRANSFERASE 1; GENOMIC DNA; HISTONE DEACETYLASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; RETINOIC ACID RECEPTOR BETA; RETINOIC ACID RECEPTOR BETA2; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; VORINOSTAT;

ARTICLE; CELL CYCLE ARREST; CELL CYCLE PROGRESSION; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; DOWN REGULATION; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GENE EXPRESSION; GENE SILENCING; PRIORITY JOURNAL; PROMOTER REGION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR GENE;

CELL CYCLE; CELL LINE, TUMOR; CPG ISLANDS; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HISTONE DEACETYLASE INHIBITORS; HUMANS; MALE; POLYMERASE CHAIN REACTION; PROSTATIC NEOPLASMS; SIGNAL TRANSDUCTION;

EID: 80051644174     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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