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Volumn 109, Issue 1, 2013, Pages 50-59

Hypoxia regulates FGFR3 expression via HIF-1α and miR-100 and contributes to cell survival in non-muscle invasive bladder cancer

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR RECEPTOR 3; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MICRORNA 100; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B;

EID: 84880255880     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/bjc.2013.240     Document Type: Article
Times cited : (63)

References (48)
  • 2
    • 80052223077 scopus 로고    scopus 로고
    • MicroRNA-associated progression pathways and potential therapeutic targets identified by integrated mRNA and microRNA expression profiling in breast cancer
    • Buffa FM, Camps C, Winchester L, Snell CE, Gee HE, Sheldon H, Taylor M, Harris AL, Ragoussis J (2011) microRNA-associated progression pathways and potential therapeutic targets identified by integrated mRNA and microRNA expression profiling in breast cancer. Cancer Res 71(17): 5635-5645.
    • (2011) Cancer Res , vol.71 , Issue.17 , pp. 5635-5645
    • Buffa, F.M.1    Camps, C.2    Winchester, L.3    Snell, C.E.4    Gee, H.E.5    Sheldon, H.6    Taylor, M.7    Harris, A.L.8    Ragoussis, J.9
  • 3
    • 75649117850 scopus 로고    scopus 로고
    • Large meta-analysis of multiple cancers reveals a common, compact and highly prognostic hypoxia metagene
    • Buffa FM, Harris AL, West CM, Miller CJ (2010) Large meta-analysis of multiple cancers reveals a common, compact and highly prognostic hypoxia metagene. Br J Cancer 102(2): 428-435.
    • (2010) Br J Cancer , vol.102 , Issue.2 , pp. 428-435
    • Buffa, F.M.1    Harris, A.L.2    West, C.M.3    Miller, C.J.4
  • 8
    • 43549124115 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1alpha expression correlates with focal macrophage infiltration, angiogenesis and unfavourable prognosis in urothelial carcinoma
    • Chai CY, Chen WT, Hung WC, Kang WY, Huang YC, Su YC, Yang CH (2008) Hypoxia-inducible factor-1alpha expression correlates with focal macrophage infiltration, angiogenesis and unfavourable prognosis in urothelial carcinoma. J Clin Pathol 61(5): 658-664.
    • (2008) J Clin Pathol , vol.61 , Issue.5 , pp. 658-664
    • Chai, C.Y.1    Chen, W.T.2    Hung, W.C.3    Kang, W.Y.4    Huang, Y.C.5    Su, Y.C.6    Yang, C.H.7
  • 9
    • 0035737586 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor 3 (FGFR3): Analyses of the S249C mutation and protein expression in primary cervical carcinomas
    • Dai H, Holm R, Kristensen GB, Abeler VM, Borresen-Dale AL, Helland A (2001) Fibroblast growth factor receptor 3 (FGFR3): analyses of the S249C mutation and protein expression in primary cervical carcinomas. Anal Cell Pathol 23(2): 45-49.
    • (2001) Anal Cell Pathol , vol.23 , Issue.2 , pp. 45-49
    • Dai, H.1    Holm, R.2    Kristensen, G.B.3    Abeler, V.M.4    Borresen-Dale, A.L.5    Helland, A.6
  • 10
    • 84857688284 scopus 로고    scopus 로고
    • Sixteen years and counting: The current understanding of fibroblast growth factor receptor 3 (FGFR3) signaling in skeletal dysplasias
    • Foldynova-Trantirkova S, Wilcox WR, Krejci P (2012) Sixteen years and counting: the current understanding of fibroblast growth factor receptor 3 (FGFR3) signaling in skeletal dysplasias. Hum Mutat 33(1): 29-41.
    • (2012) Hum Mutat , vol.33 , Issue.1 , pp. 29-41
    • Foldynova-Trantirkova, S.1    Wilcox, W.R.2    Krejci, P.3
  • 11
    • 34548803430 scopus 로고    scopus 로고
    • Translational up-regulation of the EGFR by tumor hypoxia provides a nonmutational explanation for its overexpression in human cancer
    • Franovic A, Gunaratnam L, Smith K, Robert I, Patten D, Lee S (2007) Translational up-regulation of the EGFR by tumor hypoxia provides a nonmutational explanation for its overexpression in human cancer. Proc Natl Acad Sci USA 104(32): 13092-13097.
    • (2007) Proc Natl Acad Sci USA , vol.104 , Issue.32 , pp. 13092-13097
    • Franovic, A.1    Gunaratnam, L.2    Smith, K.3    Robert, I.4    Patten, D.5    Lee, S.6
  • 13
    • 77953819013 scopus 로고    scopus 로고
    • Bladder cancer or bladder cancers? Genetically distinct malignant conditions of the urothelium
    • Goebell PJ, Knowles MA (2010) Bladder cancer or bladder cancers? Genetically distinct malignant conditions of the urothelium. Urol Oncol 28(4): 409-428.
    • (2010) Urol Oncol , vol.28 , Issue.4 , pp. 409-428
    • Goebell, P.J.1    Knowles, M.A.2
  • 15
    • 34249850360 scopus 로고    scopus 로고
    • The sulphorhodamine (SRB) assay and other approaches to testing plant extracts and derived compounds for activities related to reputed anticancer activity
    • Houghton P, Fang R, Techatanawat I, Steventon G, Hylands PJ, Lee CC (2007) The sulphorhodamine (SRB) assay and other approaches to testing plant extracts and derived compounds for activities related to reputed anticancer activity. Methods 42(4): 377-387.
    • (2007) Methods , vol.42 , Issue.4 , pp. 377-387
    • Houghton, P.1    Fang, R.2    Techatanawat, I.3    Steventon, G.4    Hylands, P.J.5    Lee, C.C.6
  • 16
    • 33750028186 scopus 로고    scopus 로고
    • Hypoxia-inducible factors HIF-1alpha and HIF-2alpha expression in bladder cancer and their associations with other angiogenesis-related proteins
    • Ioachim E, Michael M, Salmas M, Michael MM, Stavropoulos NE, Malamou- Mitsi V (2006) Hypoxia-inducible factors HIF-1alpha and HIF-2alpha expression in bladder cancer and their associations with other angiogenesis-related proteins. Urol Int 77(3): 255-263.
    • (2006) Urol Int , vol.77 , Issue.3 , pp. 255-263
    • Ioachim, E.1    Michael, M.2    Salmas, M.3    Michael, M.M.4    Stavropoulos, N.E.5    Malamou- Mitsi, V.6
  • 17
    • 33746886623 scopus 로고    scopus 로고
    • "translating" tumor hypoxia: Unfolded protein response (UPR)-dependent and UPR-independent pathways
    • Koumenis C, Wouters BG (2006) "Translating" tumor hypoxia: unfolded protein response (UPR)-dependent and UPR-independent pathways. Mol Cancer Res 4(7): 423-436.
    • (2006) Mol Cancer Res , vol.4 , Issue.7 , pp. 423-436
    • Koumenis, C.1    Wouters, B.G.2
  • 18
    • 14644394929 scopus 로고    scopus 로고
    • Cell responses to FGFR3 signalling: Growth, differentiation and apoptosis
    • L'Hote CG, Knowles MA (2005) Cell responses to FGFR3 signalling: growth, differentiation and apoptosis. Exp Cell Res 304(2): 417-431.
    • (2005) Exp Cell Res , vol.304 , Issue.2 , pp. 417-431
    • L'Hote, C.G.1    Knowles, M.A.2
  • 19
    • 78650875209 scopus 로고    scopus 로고
    • Small molecule FGF receptor inhibitors block FGFRdependent urothelial carcinoma growth in vitro and in vivo
    • Lamont FR, Tomlinson DC, Cooper PA, Shnyder SD, Chester JD, Knowles MA (2011) Small molecule FGF receptor inhibitors block FGFRdependent urothelial carcinoma growth in vitro and in vivo. Br J Cancer 104(1): 75-82.
    • (2011) Br J Cancer , vol.104 , Issue.1 , pp. 75-82
    • Lamont, F.R.1    Tomlinson, D.C.2    Cooper, P.A.3    Shnyder, S.D.4    Chester, J.D.5    Knowles, M.A.6
  • 20
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method
    • Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25(4): 402-408.
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 23
    • 24344461320 scopus 로고    scopus 로고
    • Targeting the extracellular domain of fibroblast growth factor receptor 3 with human single-chain Fv antibodies inhibits bladder carcinoma cell line proliferation
    • Martinez-Torrecuadrada J, Cifuentes G, Lopez-Serra P, Saenz P, Martinez A, Casal JI (2005) Targeting the extracellular domain of fibroblast growth factor receptor 3 with human single-chain Fv antibodies inhibits bladder carcinoma cell line proliferation. Clin Cancer Res 11(17): 6280-6290.
    • (2005) Clin Cancer Res , vol.11 , Issue.17 , pp. 6280-6290
    • Martinez-Torrecuadrada, J.1    Cifuentes, G.2    Lopez-Serra, P.3    Saenz, P.4    Martinez, A.5    Casal, J.I.6
  • 25
    • 67650531089 scopus 로고    scopus 로고
    • Genome-wide association of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha DNA binding with expression profiling of hypoxia-inducible transcripts
    • Mole DR, Blancher C, Copley RR, Pollard PJ, Gleadle JM, Ragoussis J, Ratcliffe PJ (2009) Genome-wide association of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha DNA binding with expression profiling of hypoxia-inducible transcripts. J Biol Chem 284(25): 16767-16775.
    • (2009) J Biol Chem , vol.284 , Issue.25 , pp. 16767-16775
    • Mole, D.R.1    Blancher, C.2    Copley, R.R.3    Pollard, P.J.4    Gleadle, J.M.5    Ragoussis, J.6    Ratcliffe, P.J.7
  • 28
    • 84880306327 scopus 로고    scopus 로고
    • Office for National Statistics, C. S. r. R. o. c. d. i., England. Series MB1 no. 37 National Statistics: London
    • Office for National Statistics, C. S. r. R. o. c. d. i., England. Series MB1 no. 37. National Statistics: London
  • 32
    • 33846277696 scopus 로고    scopus 로고
    • Repression of protein synthesis by miRNAs: How many mechanisms?
    • Pillai RS, Bhattacharyya SN, Filipowicz W (2007) Repression of protein synthesis by miRNAs: how many mechanisms? Trends Cell Biol 17(3): 118-126.
    • (2007) Trends Cell Biol , vol.17 , Issue.3 , pp. 118-126
    • Pillai, R.S.1    Bhattacharyya, S.N.2    Filipowicz, W.3
  • 33
    • 67349258581 scopus 로고    scopus 로고
    • The present and future burden of urinary bladder cancer in the world
    • Ploeg M, Aben KK, Kiemeney LA (2009) The present and future burden of urinary bladder cancer in the world. World J Urol 27(3): 289-293.
    • (2009) World J Urol , vol.27 , Issue.3 , pp. 289-293
    • Ploeg, M.1    Aben, K.K.2    Kiemeney, L.A.3
  • 34
    • 77953169090 scopus 로고    scopus 로고
    • Molecular genesis of non-muscleinvasive urothelial carcinoma (NMIUC)
    • Pollard C, Smith SC, Theodorescu D (2010) Molecular genesis of non-muscleinvasive urothelial carcinoma (NMIUC). Expert Rev Mol Med 12: e10.
    • (2010) Expert Rev Mol Med , vol.12
    • Pollard, C.1    Smith, S.C.2    Theodorescu, D.3
  • 39
    • 34548407864 scopus 로고    scopus 로고
    • FGFR3 protein expression and its relationship to mutation status and prognostic variables in bladder cancer
    • Tomlinson DC, Baldo O, Harnden P, Knowles MA (2007) FGFR3 protein expression and its relationship to mutation status and prognostic variables in bladder cancer. J Pathol 213(1): 91-98.
    • (2007) J Pathol , vol.213 , Issue.1 , pp. 91-98
    • Tomlinson, D.C.1    Baldo, O.2    Harnden, P.3    Knowles, M.A.4
  • 42
    • 77954370385 scopus 로고    scopus 로고
    • HIF-2alpha-mediated activation of the epidermal growth factor receptor potentiates head and neck cancer cell migration in response to hypoxia
    • Wang X, Schneider A (2010) HIF-2alpha-mediated activation of the epidermal growth factor receptor potentiates head and neck cancer cell migration in response to hypoxia. Carcinogenesis 31(7): 1202-1210.
    • (2010) Carcinogenesis , vol.31 , Issue.7 , pp. 1202-1210
    • Wang, X.1    Schneider, A.2
  • 44
    • 77956400126 scopus 로고    scopus 로고
    • Acute hypoxia induces HIF-independent monocyte adhesion to endothelial cells through increased intercellular adhesion molecule-1 expression: The role of hypoxic inhibition of prolyl hydroxylase activity for the induction of NF-kappa B
    • Winning S, Splettstoesser F, Fandrey J, Frede S (2010) Acute hypoxia induces HIF-independent monocyte adhesion to endothelial cells through increased intercellular adhesion molecule-1 expression: the role of hypoxic inhibition of prolyl hydroxylase activity for the induction of NF-kappa B. J Immunol 185(3): 1786-1793.
    • (2010) J Immunol , vol.185 , Issue.3 , pp. 1786-1793
    • Winning, S.1    Splettstoesser, F.2    Fandrey, J.3    Frede, S.4
  • 46
    • 0032478823 scopus 로고    scopus 로고
    • Selection and analysis of a mutant cell line defective in the hypoxia-inducible factor-1 alpha-subunit (HIF-1alpha). Characterization of hif-1alpha-dependent and -independent hypoxiainducible gene expression
    • Wood SM, Wiesener MS, Yeates KM, Okada N, Pugh CW, Maxwell PH, Ratcliffe PJ (1998) Selection and analysis of a mutant cell line defective in the hypoxia-inducible factor-1 alpha-subunit (HIF-1alpha). Characterization of hif-1alpha-dependent and -independent hypoxiainducible gene expression. J Biol Chem 273(14): 8360-8368.
    • (1998) J Biol Chem , vol.273 , Issue.14 , pp. 8360-8368
    • Wood, S.M.1    Wiesener, M.S.2    Yeates, K.M.3    Okada, N.4    Pugh, C.W.5    Maxwell, P.H.6    Ratcliffe, P.J.7
  • 47
    • 25444467767 scopus 로고    scopus 로고
    • Urothelial tumorigenesis: A tale of divergent pathways
    • Wu XR (2005) Urothelial tumorigenesis: a tale of divergent pathways. Nat Rev Cancer 5(9): 713-725.
    • (2005) Nat Rev Cancer , vol.5 , Issue.9 , pp. 713-725
    • Wu, X.R.1
  • 48
    • 77954603996 scopus 로고    scopus 로고
    • Ectopic expression of wild-type FGFR3 cooperates with MYC to accelerate development of B-cell lineage neoplasms
    • Zingone A, Cultraro CM, Shin DM, Bean CM, Morse 3rd HC, Janz S, Kuehl WM (2010) Ectopic expression of wild-type FGFR3 cooperates with MYC to accelerate development of B-cell lineage neoplasms. Leukemia 24(6): 1171-1178.
    • (2010) Leukemia , vol.24 , Issue.6 , pp. 1171-1178
    • Zingone, A.1    Cultraro, C.M.2    Shin, D.M.3    Bean, C.M.4    Morse III, H.C.5    Janz, S.6    Kuehl, W.M.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.