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Volumn 107, Issue 35, 2010, Pages 15449-15454

Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes

Author keywords

Cancer stem cells; FOXC1; Snail; Twist

Indexed keywords

GOOSECOID PROTEIN; PROTEIN ZEB 1; PROTEIN ZEB 2; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FOXC2; TRANSCRIPTION FACTOR SLUG; TRANSCRIPTION FACTOR SNAIL; TRANSCRIPTION FACTOR TWIST; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; UVOMORULIN;

EID: 77957262381     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1004900107     Document Type: Article
Times cited : (847)

References (59)
  • 1
    • 67650999875 scopus 로고    scopus 로고
    • The basics of epithelial-mesenchymal transition
    • Kalluri R, Weinberg RA (2009) The basics of epithelial-mesenchymal transition. J Clin Invest 119:1420-1428.
    • (2009) J Clin Invest , vol.119 , pp. 1420-1428
    • Kalluri, R.1    Weinberg, R.A.2
  • 2
    • 68749099671 scopus 로고    scopus 로고
    • Identification of selective inhibitors of cancer stem cells by high-throughput screening
    • Gupta PB, et al. (2009) Identification of selective inhibitors of cancer stem cells by high-throughput screening. Cell 138:645-659.
    • (2009) Cell , vol.138 , pp. 645-659
    • Gupta, P.B.1
  • 3
    • 2942707848 scopus 로고    scopus 로고
    • Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis
    • Yang J, et al. (2004) Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis. Cell 117:927-939.
    • (2004) Cell , vol.117 , pp. 927-939
    • Yang, J.1
  • 4
    • 0025765115 scopus 로고
    • E-cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells
    • Frixen UH, et al. (1991) E-cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells. J Cell Biol 113(1):173-185.
    • (1991) J Cell Biol , vol.113 , Issue.1 , pp. 173-185
    • Frixen, U.H.1
  • 5
    • 53249130662 scopus 로고    scopus 로고
    • Molecular signature and therapeutic perspective of the epithelial-to-mesenchymal transitions in epithelial cancers
    • Sabbah M, et al. (2008) Molecular signature and therapeutic perspective of the epithelial-to-mesenchymal transitions in epithelial cancers. Drug Resist Updat 11(4-5):123-151.
    • (2008) Drug Resist Updat , vol.11 , Issue.4-5 , pp. 123-151
    • Sabbah, M.1
  • 6
    • 43049165453 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition generates cells with properties of stem cells
    • Mani SA, et al. (2008) The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 133:704-715.
    • (2008) Cell , vol.133 , pp. 704-715
    • Mani, S.A.1
  • 7
    • 51449085561 scopus 로고    scopus 로고
    • Generation of breast cancer stem cells through epithelialmesenchymal transition
    • Morel AP, et al. (2008) Generation of breast cancer stem cells through epithelialmesenchymal transition. PLoS ONE 3:e2888.
    • (2008) PLoS ONE , vol.3
    • Morel, A.P.1
  • 8
    • 63049123066 scopus 로고    scopus 로고
    • Transitions between epithelial and mesenchymal states: Acquisition of malignant and stem cell traits
    • Polyak K, Weinberg RA (2009) Transitions between epithelial and mesenchymal states: Acquisition of malignant and stem cell traits. Nat Rev Cancer 9:265-273.
    • (2009) Nat Rev Cancer , vol.9 , pp. 265-273
    • Polyak, K.1    Weinberg, R.A.2
  • 9
    • 34250840412 scopus 로고    scopus 로고
    • The Spemann organizer gene, Goosecoid, promotes tumor metastasis
    • Hartwell KA, et al. (2006) The Spemann organizer gene, Goosecoid, promotes tumor metastasis. Proc Natl Acad Sci USA 103:18969-18974.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 18969-18974
    • Hartwell, K.A.1
  • 10
    • 0028318730 scopus 로고
    • Control of cell behavior during vertebrate development by Slug, a zinc finger gene
    • Nieto MA, Sargent MG, Wilkinson DG, Cooke J (1994) Control of cell behavior during vertebrate development by Slug, a zinc finger gene. Science 264:835-839.
    • (1994) Science , vol.264 , pp. 835-839
    • Nieto, M.A.1    Sargent, M.G.2    Wilkinson, D.G.3    Cooke, J.4
  • 11
    • 0033789680 scopus 로고    scopus 로고
    • The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells
    • Batlle E, et al. (2000) The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells. Nat Cell Biol 2(2):84-89.
    • (2000) Nat Cell Biol , vol.2 , Issue.2 , pp. 84-89
    • Batlle, E.1
  • 12
    • 0033784843 scopus 로고    scopus 로고
    • The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression
    • Cano A, et al. (2000) The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression. Nat Cell Biol 2(2):76-83.
    • (2000) Nat Cell Biol , vol.2 , Issue.2 , pp. 76-83
    • Cano, A.1
  • 13
    • 52949122883 scopus 로고    scopus 로고
    • Cell type-specific DNA methylation patterns in the human breast
    • Bloushtain-Qimron N, et al. (2008) Cell type-specific DNA methylation patterns in the human breast. Proc Natl Acad Sci USA 105:14076-14081.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 14076-14081
    • Bloushtain-Qimron, N.1
  • 14
    • 34547141894 scopus 로고    scopus 로고
    • Mesenchyme Forkhead 1 (FOXC2) plays a key role in metastasis and is associated with aggressive basal-like breast cancers
    • Mani SA, et al. (2007) Mesenchyme Forkhead 1 (FOXC2) plays a key role in metastasis and is associated with aggressive basal-like breast cancers. Proc Natl Acad Sci USA 104:10069-10074.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 10069-10074
    • Mani, S.A.1
  • 15
    • 35548974844 scopus 로고    scopus 로고
    • The transcription factor ZEB1 (deltaEF1) promotes tumour cell dedifferentiation by repressing master regulators of epithelial polarity
    • Aigner K, et al. (2007) The transcription factor ZEB1 (deltaEF1) promotes tumour cell dedifferentiation by repressing master regulators of epithelial polarity. Oncogene 26:6979-6988.
    • (2007) Oncogene , vol.26 , pp. 6979-6988
    • Aigner, K.1
  • 16
    • 54049089608 scopus 로고    scopus 로고
    • MicroRNAs as regulators of epithelial-mesenchymal transition
    • Gregory PA, Bracken CP, Bert AG, Goodall GJ (2008) MicroRNAs as regulators of epithelial-mesenchymal transition. Cell Cycle 7:3112-3118.
    • (2008) Cell Cycle , vol.7 , pp. 3112-3118
    • Gregory, P.A.1    Bracken, C.P.2    Bert, A.G.3    Goodall, G.J.4
  • 17
    • 43049103824 scopus 로고    scopus 로고
    • The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
    • Gregory PA, et al. (2008) The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. Nat Cell Biol 10:593-601.
    • (2008) Nat Cell Biol , vol.10 , pp. 593-601
    • Gregory, P.A.1
  • 18
    • 41649091906 scopus 로고    scopus 로고
    • The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2
    • Park SM, Gaur AB, Lengyel E, Peter ME (2008) The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2. Genes Dev 22:894-907.
    • (2008) Genes Dev , vol.22 , pp. 894-907
    • Park, S.M.1    Gaur, A.B.2    Lengyel, E.3    Peter, M.E.4
  • 19
    • 33646874546 scopus 로고    scopus 로고
    • The molecular portraits of breast tumors are conserved across microarray platforms
    • Hu Z, et al. (2006) The molecular portraits of breast tumors are conserved across microarray platforms. BMC Genomics 7:96.
    • (2006) BMC Genomics , vol.7 , pp. 96
    • Hu, Z.1
  • 20
    • 0035845511 scopus 로고    scopus 로고
    • Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
    • Sørlie T, et al. (2001) Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci USA 98:10869-10874.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 10869-10874
    • Sørlie, T.1
  • 21
    • 0037478605 scopus 로고    scopus 로고
    • Repeated observation of breast tumor subtypes in independent gene expression data sets
    • Sorlie T, et al. (2003) Repeated observation of breast tumor subtypes in independent gene expression data sets. Proc Natl Acad Sci USA 100:8418-8423.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 8418-8423
    • Sorlie, T.1
  • 22
    • 34548863946 scopus 로고    scopus 로고
    • Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors
    • Herschkowitz JI, et al. (2007) Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors. Genome Biol 8(5):R76.
    • (2007) Genome Biol , vol.8 , Issue.5
    • Herschkowitz, J.I.1
  • 23
    • 66249109653 scopus 로고    scopus 로고
    • Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristics
    • Hennessy BT, et al. (2009) Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristics. Cancer Res 69:4116-4124.
    • (2009) Cancer Res , vol.69 , pp. 4116-4124
    • Hennessy, B.T.1
  • 24
    • 44449111555 scopus 로고    scopus 로고
    • Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways
    • Onder TT, et al. (2008) Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways. Cancer Res 68:3645-3654.
    • (2008) Cancer Res , vol.68 , pp. 3645-3654
    • Onder, T.T.1
  • 26
    • 29144485712 scopus 로고    scopus 로고
    • SIP1/ZEB2 induces EMT by repressing genes of different epithelial cell-cell junctions
    • Vandewalle C, et al. (2005) SIP1/ZEB2 induces EMT by repressing genes of different epithelial cell-cell junctions. Nucleic Acids Res 33:6566-6578.
    • (2005) Nucleic Acids Res , vol.33 , pp. 6566-6578
    • Vandewalle, C.1
  • 27
    • 0031005659 scopus 로고    scopus 로고
    • The zinc-finger protein slug causes desmosome dissociation, an initial and necessary step for growth factor-induced epithelial-mesenchymal transition
    • Savagner P, Yamada KM, Thiery JP (1997) The zinc-finger protein slug causes desmosome dissociation, an initial and necessary step for growth factor-induced epithelial-mesenchymal transition. J Cell Biol 137:1403-1419.
    • (1997) J Cell Biol , vol.137 , pp. 1403-1419
    • Savagner, P.1    Yamada, K.M.2    Thiery, J.P.3
  • 28
    • 0035167812 scopus 로고    scopus 로고
    • The mouse Snail gene encodes a key regulator of the epithelial- mesenchymal transition
    • DOI 10.1128/MCB.21.23.8184-8188.2001
    • Carver EA, Jiang R, Lan Y, Oram KF, Gridley T (2001) The mouse snail gene encodes a key regulator of the epithelial-mesenchymal transition. Mol Cell Biol 21:8184-8188. (Pubitemid 33051806)
    • (2001) Molecular and Cellular Biology , vol.21 , Issue.23 , pp. 8184-8188
    • Carver, E.A.1    Jiang, R.2    Lan, Y.3    Oram, K.F.4    Gridley, T.5
  • 29
    • 5444267235 scopus 로고    scopus 로고
    • N-cadherin in the spotlight of cell-cell adhesion, differentiation, embryogenesis, invasion and signalling
    • Derycke LD, Bracke ME (2004) N-cadherin in the spotlight of cell-cell adhesion, differentiation, embryogenesis, invasion and signalling. Int J Dev Biol 48:463-476.
    • (2004) Int J Dev Biol , vol.48 , pp. 463-476
    • Derycke, L.D.1    Bracke, M.E.2
  • 30
    • 0027282962 scopus 로고
    • The role of E-cadherin and integrins in mesoderm differentiation and migration at the mammalian primitive streak
    • Burdsal CA, Damsky CH, Pedersen RA (1993) The role of E-cadherin and integrins in mesoderm differentiation and migration at the mammalian primitive streak. Development 118:829-844.
    • (1993) Development , vol.118 , pp. 829-844
    • Burdsal, C.A.1    Damsky, C.H.2    Pedersen, R.A.3
  • 31
    • 0029553183 scopus 로고
    • An overview of epithelio-mesenchymal transformation
    • Hay ED (1995) An overview of epithelio-mesenchymal transformation. Acta Anat (Basel) 154(1):8-20.
    • (1995) Acta Anat (Basel) , vol.154 , Issue.1 , pp. 8-20
    • Hay, E.D.1
  • 32
    • 68149163281 scopus 로고    scopus 로고
    • A developmentally regulated inducer of EMT, LBX1, contributes to breast cancer progression
    • Yu M, et al. (2009) A developmentally regulated inducer of EMT, LBX1, contributes to breast cancer progression. Genes Dev 23:1737-1742.
    • (2009) Genes Dev , vol.23 , pp. 1737-1742
    • Yu, M.1
  • 33
    • 54049084380 scopus 로고    scopus 로고
    • A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition
    • Bracken CP, et al. (2008) A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition. Cancer Res 68:7846-7854.
    • (2008) Cancer Res , vol.68 , pp. 7846-7854
    • Bracken, C.P.1
  • 34
    • 33745515023 scopus 로고    scopus 로고
    • Tumour microenvironment: TGFbeta: The molecular Jekyll and Hyde of cancer
    • Bierie B, Moses HL (2006) Tumour microenvironment: TGFbeta: The molecular Jekyll and Hyde of cancer. Nat Rev Cancer 6:506-520.
    • (2006) Nat Rev Cancer , vol.6 , pp. 506-520
    • Bierie, B.1    Moses, H.L.2
  • 35
    • 33947246042 scopus 로고    scopus 로고
    • A novel small-molecule inhibitor of transforming growth factor beta type I receptor kinase (SM16) inhibits murine mesothelioma tumor growth in vivo and prevents tumor recurrence after surgical resection
    • Suzuki E, et al. (2007) A novel small-molecule inhibitor of transforming growth factor beta type I receptor kinase (SM16) inhibits murine mesothelioma tumor growth in vivo and prevents tumor recurrence after surgical resection. Cancer Res 67:2351-2359.
    • (2007) Cancer Res , vol.67 , pp. 2351-2359
    • Suzuki, E.1
  • 36
    • 0026722283 scopus 로고
    • Dorsal-twist interactions establish snail expression in the presumptive mesoderm of the Drosophila embryo
    • Ip YT, Park RE, Kosman D, Yazdanbakhsh K, Levine M (1992) Dorsal-twist interactions establish snail expression in the presumptive mesoderm of the Drosophila embryo. Genes Dev 6:1518-1530.
    • (1992) Genes Dev , vol.6 , pp. 1518-1530
    • Ip, Y.T.1    Park, R.E.2    Kosman, D.3    Yazdanbakhsh, K.4    Levine, M.5
  • 37
    • 2442705493 scopus 로고    scopus 로고
    • Snail blocks the cell cycle and confers resistance to cell death
    • Vega S, et al. (2004) Snail blocks the cell cycle and confers resistance to cell death. Genes Dev 18:1131-1143.
    • (2004) Genes Dev , vol.18 , pp. 1131-1143
    • Vega, S.1
  • 38
    • 51649123049 scopus 로고    scopus 로고
    • Slug (SNAI2) down-regulation by RNA interference facilitates apoptosis and inhibits invasive growth in neuroblastoma preclinical models
    • Vitali R, et al. (2008) Slug (SNAI2) down-regulation by RNA interference facilitates apoptosis and inhibits invasive growth in neuroblastoma preclinical models. Clin Cancer Res 14:4622-4630.
    • (2008) Clin Cancer Res , vol.14 , pp. 4622-4630
    • Vitali, R.1
  • 39
    • 19044372843 scopus 로고    scopus 로고
    • Slug, a highly conserved zinc finger transcriptional repressor, protects hematopoietic progenitor cells from radiation-induced apoptosis in vivo
    • Inoue A, et al. (2002) Slug, a highly conserved zinc finger transcriptional repressor, protects hematopoietic progenitor cells from radiation-induced apoptosis in vivo. Cancer Cell 2:279-288.
    • (2002) Cancer Cell , vol.2 , pp. 279-288
    • Inoue, A.1
  • 40
    • 4644290527 scopus 로고    scopus 로고
    • Down-regulation of SNAIL suppresses MIN mouse tumorigenesis: Modulation of apoptosis, proliferation, and fractal dimension
    • Roy HK, et al. (2004) Down-regulation of SNAIL suppresses MIN mouse tumorigenesis: Modulation of apoptosis, proliferation, and fractal dimension. Mol Cancer Ther 3:1159-1165.
    • (2004) Mol Cancer Ther , vol.3 , pp. 1159-1165
    • Roy, H.K.1
  • 41
    • 70349273757 scopus 로고    scopus 로고
    • SIP1 protein protects cells from DNA damage-induced apoptosis and has independent prognostic value in bladder cancer
    • Sayan AE, et al. (2009) SIP1 protein protects cells from DNA damage-induced apoptosis and has independent prognostic value in bladder cancer. Proc Natl Acad Sci USA 106:14884-14889.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 14884-14889
    • Sayan, A.E.1
  • 42
    • 77953642516 scopus 로고    scopus 로고
    • DDR1 regulates the stabilization of cell surface E-cadherin and E-cadherin-mediated cell aggregation
    • Eswaramoorthy R, et al. (2010) DDR1 regulates the stabilization of cell surface E-cadherin and E-cadherin-mediated cell aggregation. J Cell Physiol 224:387-397.
    • (2010) J Cell Physiol , vol.224 , pp. 387-397
    • Eswaramoorthy, R.1
  • 43
    • 68849099260 scopus 로고    scopus 로고
    • DDR1/E-cadherin complex regulates the activation of DDR1 and cell spreading
    • Wang CZ, Yeh YC, Tang MJ (2009) DDR1/E-cadherin complex regulates the activation of DDR1 and cell spreading. Am J Physiol Cell Physiol 297:C419-C429.
    • (2009) Am J Physiol Cell Physiol , vol.297
    • Wang, C.Z.1    Yeh, Y.C.2    Tang, M.J.3
  • 44
    • 55849151326 scopus 로고    scopus 로고
    • Switching in discoid domain receptor expressions in SLUG-induced epithelial-mesenchymal transition
    • Maeyama M, et al. (2008) Switching in discoid domain receptor expressions in SLUG-induced epithelial-mesenchymal transition. Cancer 113:2823-2831.
    • (2008) Cancer , vol.113 , pp. 2823-2831
    • Maeyama, M.1
  • 45
    • 77954860302 scopus 로고    scopus 로고
    • Epithelial mesenchymal transition traits in human breast cancer cell lines parallel the CD44(hi/)CD24 (lo/-) stem cell phenotype in human breast cancer
    • Blick T, et al. (2010) Epithelial mesenchymal transition traits in human breast cancer cell lines parallel the CD44(hi/)CD24 (lo/-) stem cell phenotype in human breast cancer. J Mammary Gland Biol Neoplasia 15:235-252.
    • (2010) J Mammary Gland Biol Neoplasia , vol.15 , pp. 235-252
    • Blick, T.1
  • 46
    • 27344435774 scopus 로고    scopus 로고
    • Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
    • Subramanian A, et al. (2005) Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci USA 102:15545-15550.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 15545-15550
    • Subramanian, A.1
  • 47
    • 0038054341 scopus 로고    scopus 로고
    • PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
    • Mootha VK, et al. (2003) PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat Genet 34:267-273.
    • (2003) Nat Genet , vol.34 , pp. 267-273
    • Mootha, V.K.1
  • 48
    • 42049113862 scopus 로고    scopus 로고
    • Follistatin antagonizes transforming growth factor-beta3-induced epithelial-mesenchymal transition in vitro: Implications for murine palatal development supported by microarray analysis
    • Nogai H, et al. (2008) Follistatin antagonizes transforming growth factor-beta3-induced epithelial-mesenchymal transition in vitro: Implications for murine palatal development supported by microarray analysis. Differentiation 76:404-416.
    • (2008) Differentiation , vol.76 , pp. 404-416
    • Nogai, H.1
  • 49
    • 35248889408 scopus 로고    scopus 로고
    • EGFR associated expression profiles vary with breast tumor subtype
    • Hoadley KA, et al. (2007) EGFR associated expression profiles vary with breast tumor subtype. BMC Genomics 8:258.
    • (2007) BMC Genomics , vol.8 , pp. 258
    • Hoadley, K.A.1
  • 50
    • 33845209913 scopus 로고    scopus 로고
    • A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes
    • Neve RM, et al. (2006) A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. Cancer Cell 10:515-527.
    • (2006) Cancer Cell , vol.10 , pp. 515-527
    • Neve, R.M.1
  • 51
    • 28044462186 scopus 로고    scopus 로고
    • Gene-expression profiling and the future of adjuvant therapy
    • DOI 10.1634/theoncologist.10-90002-30
    • van de Vijver M (2005) Gene-expression profiling and the future of adjuvant therapy. Oncologist 10 (Suppl 2):30-34. (Pubitemid 41692641)
    • (2005) Oncologist , vol.10 , Issue.SUPPL. 2 , pp. 30-34
    • Van De Vijver, M.1
  • 52
    • 58149334773 scopus 로고    scopus 로고
    • A stroma-related gene signature predicts resistance to neoadjuvant chemotherapy in breast cancer
    • Farmer P, et al. (2009) A stroma-related gene signature predicts resistance to neoadjuvant chemotherapy in breast cancer. Nat Med 15(1):68-74.
    • (2009) Nat Med , vol.15 , Issue.1 , pp. 68-74
    • Farmer, P.1
  • 53
    • 69549131213 scopus 로고    scopus 로고
    • Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features
    • Creighton CJ, et al. (2009) Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features. Proc Natl Acad Sci USA 106:13820-13825.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 13820-13825
    • Creighton, C.J.1
  • 54
    • 33749030177 scopus 로고    scopus 로고
    • Pharmacogenomic predictor of sensitivity to preoperative chemotherapy with paclitaxel and fluorouracil, doxorubicin, and cyclophosphamide in breast cancer
    • Hess KR, et al. (2006) Pharmacogenomic predictor of sensitivity to preoperative chemotherapy with paclitaxel and fluorouracil, doxorubicin, and cyclophosphamide in breast cancer. J Clin Oncol 24:4236-4244.
    • (2006) J Clin Oncol , vol.24 , pp. 4236-4244
    • Hess, K.R.1
  • 55
    • 68349130357 scopus 로고    scopus 로고
    • KConFab (2009) Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers
    • Lim E, et al. (2009) kConFab (2009) Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers. Nat Med 15:907-913.
    • (2009) Nat Med , vol.15 , pp. 907-913
    • Lim, E.1
  • 56
    • 33846509776 scopus 로고    scopus 로고
    • Metaplastic carcinoma of the breast, an unusual disease with worse prognosis: The experience of the European Institute of Oncology and review of the literature
    • Luini A, et al. (2007) Metaplastic carcinoma of the breast, an unusual disease with worse prognosis: The experience of the European Institute of Oncology and review of the literature. Breast Cancer Res Treat 101:349-353.
    • (2007) Breast Cancer Res Treat , vol.101 , pp. 349-353
    • Luini, A.1
  • 58
    • 0035177216 scopus 로고    scopus 로고
    • Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells
    • Elenbaas B, et al. (2001) Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells. Genes Dev 15(1):50-65.
    • (2001) Genes Dev , vol.15 , Issue.1 , pp. 50-65
    • Elenbaas, B.1
  • 59
    • 0029677185 scopus 로고    scopus 로고
    • Human breast cancer cell lines as models of growth regulation and disease progression
    • Ethier SP (1996) Human breast cancer cell lines as models of growth regulation and disease progression. J Mammary Gland Biol Neoplasia 1(1):111-121.
    • (1996) J Mammary Gland Biol Neoplasia , vol.1 , Issue.1 , pp. 111-121
    • Ethier, S.P.1


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