-
1
-
-
84860486816
-
Burden of disease caused by otitis media: Systematic review and global estimates
-
Monasta L, Ronfani L, Marchetti F, et al. Burden of disease caused by otitis media: systematic review and global estimates. PLoS ONE. 2012;7.
-
(2012)
PLoS ONE
, vol.7
-
-
Monasta, L.1
Ronfani, L.2
Marchetti, F.3
-
2
-
-
0024409846
-
Epidemiologic patterns in childhood hearing loss: A review
-
2670797 1:STN:280:DyaL1MzlvVCksw%3D%3D
-
Davidson J, Hyde M, Alberti P. Epidemiologic patterns in childhood hearing loss: a review. Int J Pediatr Otorhinolaryngol. 1989;17:239-66.
-
(1989)
Int J Pediatr Otorhinolaryngol
, vol.17
, pp. 239-266
-
-
Davidson, J.1
Hyde, M.2
Alberti, P.3
-
3
-
-
78650795232
-
Grommets (ventilation tubes) for hearing loss associated with otitis media with effusion in children
-
Browning G, Rovers M, Williamson I, et al. Grommets (ventilation tubes) for hearing loss associated with otitis media with effusion in children. Cochrane Database Syst Rev. 2010;10.
-
(2010)
Cochrane Database Syst Rev
, vol.10
-
-
Browning, G.1
Rovers, M.2
Williamson, I.3
-
4
-
-
67649819586
-
Mouse models for human otitis media
-
19272362 1:CAS:528:DC%2BD1MXnsFaiurg%3D
-
Trune D, Zheng Q. Mouse models for human otitis media. Brain Res. 2009;1277:90-103.
-
(2009)
Brain Res
, vol.1277
, pp. 90-103
-
-
Trune, D.1
Zheng, Q.2
-
5
-
-
34248206065
-
Accurate consent for insertion and later removal of grommets
-
17403263 1:STN:280:DC%2BD2s3gtFShtg%3D%3D
-
Sood S, Waddell A. Accurate consent for insertion and later removal of grommets. The Journal of laryngology and otology. 2007;121:338-40.
-
(2007)
The Journal of Laryngology and Otology
, vol.121
, pp. 338-340
-
-
Sood, S.1
Waddell, A.2
-
6
-
-
77149163297
-
Epidemiology, natural history, and risk factors: Panel report from the Ninth International Research Conference on Otitis Media
-
19836843
-
Daly K, Hoffman H, Kvaerner K, et al. Epidemiology, natural history, and risk factors: panel report from the Ninth International Research Conference on Otitis Media. Int J Pediatr Otorhinolaryngol. 2010;74:231-40.
-
(2010)
Int J Pediatr Otorhinolaryngol
, vol.74
, pp. 231-240
-
-
Daly, K.1
Hoffman, H.2
Kvaerner, K.3
-
7
-
-
34548348780
-
The mouse ascending: Perspectives for human-disease models
-
17762889 1:CAS:528:DC%2BD2sXpslGisr4%3D
-
Rosenthal N, Brown S. The mouse ascending: perspectives for human-disease models. Nat Cell Biol. 2007;9:993-9.
-
(2007)
Nat Cell Biol
, vol.9
, pp. 993-999
-
-
Rosenthal, N.1
Brown, S.2
-
8
-
-
33745612952
-
Mouse models as a tool to unravel the genetic basis for human otitis media
-
16917982 1:CAS:528:DC%2BD28XmslGhsLY%3D
-
Zheng Q, Hardisty-Hughes R, Brown S. Mouse models as a tool to unravel the genetic basis for human otitis media. Brain Res. 2006;1091:9-15.
-
(2006)
Brain Res
, vol.1091
, pp. 9-15
-
-
Zheng, Q.1
Hardisty-Hughes, R.2
Brown, S.3
-
9
-
-
33745624550
-
Mouse models of induced otitis media
-
16764829 1:CAS:528:DC%2BD28XmslGhsrY%3D
-
Ryan A, Ebmeyer J, Furukawa M, et al. Mouse models of induced otitis media. Brain Res. 2006;1091:3-8.
-
(2006)
Brain Res
, vol.1091
, pp. 3-8
-
-
Ryan, A.1
Ebmeyer, J.2
Furukawa, M.3
-
10
-
-
79951554988
-
Unraveling the genetics of otitis media: From mouse to human and back again
-
21107580 1:CAS:528:DC%2BC3MXht1WhsbY%3D
-
Rye M, Bhutta M, Cheeseman M, et al. Unraveling the genetics of otitis media: from mouse to human and back again. Mamm Genome. 2011;22(1-2):66-82.
-
(2011)
Mamm Genome
, vol.22
, Issue.1-2
, pp. 66-82
-
-
Rye, M.1
Bhutta, M.2
Cheeseman, M.3
-
11
-
-
73349135989
-
The functional annotation of mammalian genomes: The challenge of phenotyping
-
19689210 1:CAS:528:DC%2BD1MXhsF2qtrnK
-
Brown S, Wurst W, Kühn R, et al. The functional annotation of mammalian genomes: the challenge of phenotyping. Annu Rev Genet. 2009;43:305-33.
-
(2009)
Annu Rev Genet
, vol.43
, pp. 305-333
-
-
Brown, S.1
Wurst, W.2
Kühn, R.3
-
12
-
-
58149252618
-
The mouse genome
-
18753767 1:CAS:528:DC%2BD1cXhtVCns7%2FL
-
Brown S, Hancock J. The mouse genome. Genome Dynamics. 2006;2:33-45.
-
(2006)
Genome Dynamics
, vol.2
, pp. 33-45
-
-
Brown, S.1
Hancock, J.2
-
13
-
-
40849106619
-
Quiet as a mouse: Dissecting the molecular and genetic basis of hearing
-
18283275 1:CAS:528:DC%2BD1cXjtlGnurY%3D
-
Brown S, Hardisty-Hughes R, Mburu P. Quiet as a mouse: dissecting the molecular and genetic basis of hearing. Nat Rev Genet. 2008;9:277-90.
-
(2008)
Nat Rev Genet
, vol.9
, pp. 277-290
-
-
Brown, S.1
Hardisty-Hughes, R.2
Mburu, P.3
-
14
-
-
84870465774
-
Mouse models of otitis media: Strengths and limitations
-
22661304
-
Bhutta M. Mouse models of otitis media: strengths and limitations. Otolaryngol Head Neck Surg. 2012;147:611-4.
-
(2012)
Otolaryngol Head Neck Surg
, vol.147
, pp. 611-614
-
-
Bhutta, M.1
-
15
-
-
71449115968
-
Development of a non-invasive murine infection model for acute otitis media
-
19762437 1:CAS:528:DC%2BD1MXhs1Wht7vN
-
Stol K, van Selm S, van den Berg S, et al. Development of a non-invasive murine infection model for acute otitis media. Microbiology. 2009;155:4135-44.
-
(2009)
Microbiology
, vol.155
, pp. 4135-4144
-
-
Stol, K.1
Van Selm, S.2
Van Den Berg, S.3
-
16
-
-
40049088170
-
Mouse models for the study of mucosal vaccination against otitis media
-
18295938 1:CAS:528:DC%2BD1cXivFyhs7k%3D
-
Sabirov A, Metzger D. Mouse models for the study of mucosal vaccination against otitis media. Vaccine. 2008;26:1501-24.
-
(2008)
Vaccine
, vol.26
, pp. 1501-1524
-
-
Sabirov, A.1
Metzger, D.2
-
17
-
-
4444262688
-
The knockout mouse project
-
15340423 1:CAS:528:DC%2BD2cXntFSktb8%3D
-
Austin C, Battey J, Bradley A, et al. The knockout mouse project. Nat Genet. 2004;36:921-4.
-
(2004)
Nat Genet
, vol.36
, pp. 921-924
-
-
Austin, C.1
Battey, J.2
Bradley, A.3
-
18
-
-
0034425410
-
A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse
-
10932191 1:CAS:528:DC%2BD3cXlvVeqsr4%3D
-
Nolan P, Peters J, Strivens M, et al. A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse. Nat Genet. 2000;25:440-3.
-
(2000)
Nat Genet
, vol.25
, pp. 440-443
-
-
Nolan, P.1
Peters, J.2
Strivens, M.3
-
19
-
-
52949150758
-
ENU mutagenesis, a way forward to understand gene function
-
18949851 1:CAS:528:DC%2BD1cXht1SnsbjE
-
Acevedo-Arozena A, Wells S, Potter P, et al. ENU mutagenesis, a way forward to understand gene function. Annual review of genomics and human genetics. 2008;9:49-69.
-
(2008)
Annual Review of Genomics and Human Genetics
, vol.9
, pp. 49-69
-
-
Acevedo-Arozena, A.1
Wells, S.2
Potter, P.3
-
20
-
-
0026336871
-
Immunoprophylaxis of otitis media
-
1805562 1:STN:280:DyaK383hsVaksA%3D%3D
-
Giebink G. Immunoprophylaxis of otitis media. Adv Exp Med Biol. 1991;303:149-58.
-
(1991)
Adv Exp Med Biol
, vol.303
, pp. 149-158
-
-
Giebink, G.1
-
21
-
-
3142724031
-
Toll-like receptor signalling
-
15229469 1:CAS:528:DC%2BD2cXlt1Cqur0%3D
-
Akira S, Takeda. Toll-like receptor signalling. Nat Rev Immunol. 2004;4:499-511.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 499-511
-
-
Akira, S.1
Takeda2
-
22
-
-
77951260924
-
The role of pattern-recognition receptors in innate immunity: Update on Toll-like receptors
-
20404851 1:CAS:528:DC%2BC3cXkvFSjsrc%3D
-
Kawai T, Akira S. The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nature Immunology. 2010;11:373-84.
-
(2010)
Nature Immunology
, vol.11
, pp. 373-384
-
-
Kawai, T.1
Akira, S.2
-
23
-
-
32944464648
-
Pathogen recognition and innate immunity
-
16497588 1:CAS:528:DC%2BD28Xit1Kltb8%3D
-
Akira S, Uematsu S, Takeuchi O. Pathogen recognition and innate immunity. Cell. 2006;124:783-801.
-
(2006)
Cell
, vol.124
, pp. 783-801
-
-
Akira, S.1
Uematsu, S.2
Takeuchi, O.3
-
24
-
-
84862907911
-
The role of DNA sensing and innate immune receptor TLR9 in otitis media
-
21239460 1:CAS:528:DC%2BC38XivFSqtL4%3D
-
Leichtle A, Hernandez M, Lee J, et al. The role of DNA sensing and innate immune receptor TLR9 in otitis media. Innate Immunity. 2012;18:3-13.
-
(2012)
Innate Immunity
, vol.18
, pp. 3-13
-
-
Leichtle, A.1
Hernandez, M.2
Lee, J.3
-
25
-
-
33846487260
-
Role of Toll-like receptor 4 in innate immune responses in a mouse model of acute otitis media
-
17266713 1:CAS:528:DC%2BD2sXhvVOitL4%3D
-
Hirano T, Kodama S, Fujita K, et al. Role of Toll-like receptor 4 in innate immune responses in a mouse model of acute otitis media. FEMS Immunology and Medical Microbiology. 2007;49:75-83.
-
(2007)
FEMS Immunology and Medical Microbiology
, vol.49
, pp. 75-83
-
-
Hirano, T.1
Kodama, S.2
Fujita, K.3
-
26
-
-
67949104967
-
TLR4-mediated induction of TLR2 signaling is critical in the pathogenesis and resolution of otitis media
-
19586996 1:CAS:528:DC%2BD1MXhtVyiur%2FJ
-
Leichtle A, Hernandez M, Pak K, et al. TLR4-mediated induction of TLR2 signaling is critical in the pathogenesis and resolution of otitis media. Innate immunity. 2009;15:205-15.
-
(2009)
Innate Immunity
, vol.15
, pp. 205-215
-
-
Leichtle, A.1
Hernandez, M.2
Pak, K.3
-
27
-
-
56749083659
-
Myeloid differentiation primary response gene 88 is required for the resolution of otitis media
-
18986247
-
Hernandez M, Leichtle A, Pak K, et al. Myeloid differentiation primary response gene 88 is required for the resolution of otitis media. J Infect Dis. 2008;198:1862-9.
-
(2008)
J Infect Dis
, vol.198
, pp. 1862-1869
-
-
Hernandez, M.1
Leichtle, A.2
Pak, K.3
-
28
-
-
28444459897
-
How Toll-like receptors and Nod-like receptors contribute to innate immunity in mammals
-
16303096 1:CAS:528:DC%2BD2MXhtleku7jL
-
Fritz J, Girardin S. How Toll-like receptors and Nod-like receptors contribute to innate immunity in mammals. Journal of Endotoxin Research. 2005;11:390-4.
-
(2005)
Journal of Endotoxin Research
, vol.11
, pp. 390-394
-
-
Fritz, J.1
Girardin, S.2
-
29
-
-
84877835134
-
Complement activation in pediatric patients with recurrent acute otitis media
-
Ahead of print
-
He Y, Scholes M, Wiet G, et al. Complement activation in pediatric patients with recurrent acute otitis media. Int J Pediatr Otorhinolaryngol. 2013. Ahead of print.
-
(2013)
Int J Pediatr Otorhinolaryngol
-
-
He, Y.1
Scholes, M.2
Wiet, G.3
-
30
-
-
77349106655
-
Enhanced susceptibility to acute pneumococcal otitis media in mice deficient in complement C1qa, factor B, and factor B/C2
-
20065024 1:CAS:528:DC%2BC3cXjtFais70%3D
-
Tong H, Li Y, Stahl G, et al. Enhanced susceptibility to acute pneumococcal otitis media in mice deficient in complement C1qa, factor B, and factor B/C2. Infect Immun. 2010;78:976-83.
-
(2010)
Infect Immun
, vol.78
, pp. 976-983
-
-
Tong, H.1
Li, Y.2
Stahl, G.3
-
31
-
-
71149085576
-
The role of complement in innate and adaptive immunity to pneumococcal colonization and sepsis in a murine model
-
19892042 1:CAS:528:DC%2BD1MXhsFaiu77I
-
Bogaert D, Thompson C, Trzcinski K, et al. The role of complement in innate and adaptive immunity to pneumococcal colonization and sepsis in a murine model. Vaccine. 2010;28:681-5.
-
(2010)
Vaccine
, vol.28
, pp. 681-685
-
-
Bogaert, D.1
Thompson, C.2
Trzcinski, K.3
-
32
-
-
12344311144
-
Tbx1 is required for proper neural crest migration and to stabilize spatial patterns during middle and inner ear development
-
15652707 1:CAS:528:DC%2BD2MXkvFensg%3D%3D
-
Moraes F, Nóvoa A, Jerome-Majewska LA, et al. Tbx1 is required for proper neural crest migration and to stabilize spatial patterns during middle and inner ear development. Mech Dev. 2005;122:199-212.
-
(2005)
Mech Dev
, vol.122
, pp. 199-212
-
-
Moraes, F.1
Nóvoa, A.2
Jerome-Majewska, L.A.3
-
33
-
-
70349334443
-
Otitis media in a mouse model for Down syndrome
-
19765102
-
Han F, Yu H, Zhang J, et al. Otitis media in a mouse model for Down syndrome. Int J Exp Pathol. 2009;90:480-8.
-
(2009)
Int J Exp Pathol
, vol.90
, pp. 480-488
-
-
Han, F.1
Yu, H.2
Zhang, J.3
-
34
-
-
0032007010
-
Lack of correlation between impaired T cell production, immunodeficiency, and other phenotypic features in chromosome 22q11.2 deletion syndromes
-
9473376 1:STN:280:DyaK1c7ktF2qtA%3D%3D
-
Sullivan K, Jawad A, Randall P, et al. Lack of correlation between impaired T cell production, immunodeficiency, and other phenotypic features in chromosome 22q11.2 deletion syndromes. Clin Immunol Immunopathol. 1998;86:141-6.
-
(1998)
Clin Immunol Immunopathol
, vol.86
, pp. 141-146
-
-
Sullivan, K.1
Jawad, A.2
Randall, P.3
-
35
-
-
44149086625
-
Genetic modifiers of the physical malformations in velo-cardio-facial syndrome/DiGeorge syndrome
-
18636633
-
Aggarwal V, Morrow B. Genetic modifiers of the physical malformations in velo-cardio-facial syndrome/DiGeorge syndrome. Developmental Disabilities Research Reviews. 2008;14:19-25.
-
(2008)
Developmental Disabilities Research Reviews
, vol.14
, pp. 19-25
-
-
Aggarwal, V.1
Morrow, B.2
-
36
-
-
19944420858
-
Immune abnormalities are a frequent manifestation of Kabuki syndrome
-
15887282
-
Hoffman J, Ciprero K, Sullivan K, et al. Immune abnormalities are a frequent manifestation of Kabuki syndrome. Am J Med Genet. 2005;135:278-81.
-
(2005)
Am J Med Genet
, vol.135
, pp. 278-281
-
-
Hoffman, J.1
Ciprero, K.2
Sullivan, K.3
-
37
-
-
66049158683
-
CHARGE (coloboma, heart defect, atresia choanae, retarded growth and development, genital hypoplasia, ear anomalies/deafness) syndrome and chromosome 22q11.2 deletion syndrome: A comparison of immunologic and nonimmunologic phenotypic features
-
Jyonouchi S, McDonald-McGinn D, Bale S, et al. CHARGE (coloboma, heart defect, atresia choanae, retarded growth and development, genital hypoplasia, ear anomalies/deafness) syndrome and chromosome 22q11.2 deletion syndrome: a comparison of immunologic and nonimmunologic phenotypic features. Pediatrics. 2009;123:7.
-
(2009)
Pediatrics
, vol.123
, pp. 7
-
-
Jyonouchi, S.1
McDonald-Mcginn, D.2
Bale, S.3
-
38
-
-
64649097543
-
Intrinsic defect of the immune system in children with Down syndrome: A review
-
19250275 1:STN:280:DC%2BD1M3ptlOqsg%3D%3D
-
Kusters MA, Verstegen R, Gemen E, et al. Intrinsic defect of the immune system in children with Down syndrome: a review. Clinical and Experimental Immunology. 2009;156:189-93.
-
(2009)
Clinical and Experimental Immunology
, vol.156
, pp. 189-193
-
-
Kusters, M.A.1
Verstegen, R.2
Gemen, E.3
-
39
-
-
79952495602
-
Infections and immunodeficiency in Down syndrome
-
21352207 1:CAS:528:DC%2BC3MXlt1WnsLk%3D
-
Ram G, Chinen J. Infections and immunodeficiency in Down syndrome. Clinical and Experimental Immunology. 2011;164:9-16.
-
(2011)
Clinical and Experimental Immunology
, vol.164
, pp. 9-16
-
-
Ram, G.1
Chinen, J.2
-
40
-
-
78650970552
-
Chronic otitis media in mucopolysaccharidosis may not be due to Eustachian tube dysfunction
-
20833438
-
Bhutta M. Chronic otitis media in mucopolysaccharidosis may not be due to Eustachian tube dysfunction. Int J Pediatr Otorhinolaryngol. 2011;75:140-1.
-
(2011)
Int J Pediatr Otorhinolaryngol
, vol.75
, pp. 140-141
-
-
Bhutta, M.1
-
41
-
-
33845987087
-
Age-related functional and histopathological changes of the ear in the MPS i mouse
-
17101178
-
Schachern P, Cureoglu S, Tsuprun V, et al. Age-related functional and histopathological changes of the ear in the MPS I mouse. Int J Pediatr Otorhinolaryngol. 2007;71:197-203.
-
(2007)
Int J Pediatr Otorhinolaryngol
, vol.71
, pp. 197-203
-
-
Schachern, P.1
Cureoglu, S.2
Tsuprun, V.3
-
42
-
-
77955022207
-
Characterization of a novel mucopolysaccharidosis type II mouse model and recombinant AAV2/8 vector-mediated gene therapy
-
20652491 1:CAS:528:DC%2BC3cXptFGmtbw%3D
-
Jung S-C, Park E-S, Choi E, et al. Characterization of a novel mucopolysaccharidosis type II mouse model and recombinant AAV2/8 vector-mediated gene therapy. Mol Cells. 2010;30:13-8.
-
(2010)
Mol Cells
, vol.30
, pp. 13-18
-
-
Jung, S.-C.1
Park, E.-S.2
Choi, E.3
-
43
-
-
40749147092
-
Development of sensory, motor and behavioral deficits in the murine model of Sanfilippo syndrome type B
-
Heldermon C, Hennig A, Ohlemiller K, et al. Development of sensory, motor and behavioral deficits in the murine model of Sanfilippo syndrome type B. PLoS One. 2007;2(8).
-
(2007)
PLoS One
, vol.2
, Issue.8
-
-
Heldermon, C.1
Hennig, A.2
Ohlemiller, K.3
-
44
-
-
0035096842
-
A novel model of murine mucopolysaccharidosis type VII due to an intracisternal a particle element transposition into the beta-glucuronidase gene: Clinical and pathologic findings
-
11228259 1:CAS:528:DC%2BD3MXit1aksbg%3D
-
Vogler C, Levy B, Galvin N, et al. A novel model of murine mucopolysaccharidosis type VII due to an intracisternal a particle element transposition into the beta-glucuronidase gene: clinical and pathologic findings. Pediatr Res. 2001;49:342-8.
-
(2001)
Pediatr Res
, vol.49
, pp. 342-348
-
-
Vogler, C.1
Levy, B.2
Galvin, N.3
-
45
-
-
84865569996
-
Auditory characteristics and therapeutic effects of enzyme replacement in mouse model of the mucopolysaccharidosis (MPS) II
-
22847837 The research outlined in this paper establishes an important link to therapeutics for syndromic OM
-
• Hong S, Chu H, Kim K, et al. Auditory characteristics and therapeutic effects of enzyme replacement in mouse model of the mucopolysaccharidosis (MPS) II. Am J Med Genet. 2012;158A:2131-8. The research outlined in this paper establishes an important link to therapeutics for syndromic OM.
-
(2012)
Am J Med Genet
, vol.158
, pp. 2131-2138
-
-
Hong, S.1
Chu, H.2
Kim, K.3
-
46
-
-
65349109799
-
Inactivation of Chibby affects function of motile airway cilia
-
19364920 1:CAS:528:DC%2BD1MXlt1yjt7g%3D
-
Voronina V, Takemaru K-I, Treuting P, et al. Inactivation of Chibby affects function of motile airway cilia. J Cell Biol. 2009;185:225-33.
-
(2009)
J Cell Biol
, vol.185
, pp. 225-233
-
-
Voronina, V.1
Takemaru, K.-I.2
Treuting, P.3
-
47
-
-
0037087624
-
Loss of function of axonemal dynein Mdnah5 causes primary ciliary dyskinesia and hydrocephalus
-
11912187
-
Ibañez-Tallon I, Gorokhova S, Heintz N. Loss of function of axonemal dynein Mdnah5 causes primary ciliary dyskinesia and hydrocephalus. Hum Mol Genet. 2002;11:715-21.
-
(2002)
Hum Mol Genet
, vol.11
, pp. 715-721
-
-
Ibañez-Tallon, I.1
Gorokhova, S.2
Heintz, N.3
-
48
-
-
84857054679
-
Static respiratory cilia associated with mutations in Dnahc11/DNAH11: A mouse model of PCD
-
22102620 1:CAS:528:DC%2BC38XitF2kurY%3D
-
Lucas J, Adam E, Goggin P, et al. Static respiratory cilia associated with mutations in Dnahc11/DNAH11: a mouse model of PCD. Hum Mutat. 2012;33:495-503.
-
(2012)
Hum Mutat
, vol.33
, pp. 495-503
-
-
Lucas, J.1
Adam, E.2
Goggin, P.3
-
49
-
-
0028800896
-
Nasal and middle ear ciliary beat frequency in chronic suppurative otitis media
-
8582083 1:STN:280:DyaK287lsVGlsQ%3D%3D
-
Agius A, Wake M, Pahor A, et al. Nasal and middle ear ciliary beat frequency in chronic suppurative otitis media. Clinical Otolaryngology and Allied Sciences. 1995;20:470-4.
-
(1995)
Clinical Otolaryngology and Allied Sciences
, vol.20
, pp. 470-474
-
-
Agius, A.1
Wake, M.2
Pahor, A.3
-
50
-
-
70350567733
-
The ciliary beat frequency of middle ear mucosa in children with chronic secretory otitis media
-
19387677
-
Gurr A, Stark T, Pearson M, et al. The ciliary beat frequency of middle ear mucosa in children with chronic secretory otitis media. Eur Arch Otorhinolaryngol. 2009;266:1865-70.
-
(2009)
Eur Arch Otorhinolaryngol
, vol.266
, pp. 1865-1870
-
-
Gurr, A.1
Stark, T.2
Pearson, M.3
-
51
-
-
0025299159
-
The effect of middle ear effusions from children on in vitro ciliary activity
-
2393565 1:STN:280:DyaK3czms1Sgsg%3D%3D
-
Takeuchi K, Saida S, Majima Y, et al. The effect of middle ear effusions from children on in vitro ciliary activity. Eur Arch Otorhinolaryngol. 1990;247:323-5.
-
(1990)
Eur Arch Otorhinolaryngol
, vol.247
, pp. 323-325
-
-
Takeuchi, K.1
Saida, S.2
Majima, Y.3
-
52
-
-
0028838134
-
Effects of human middle ear effusions on the mucociliary system of the tubotympanum in the guinea pig
-
7718226 1:STN:280:DyaK2M3jsVejsg%3D%3D
-
Ohashi Y, Nakai Y, Ohno Y, et al. Effects of human middle ear effusions on the mucociliary system of the tubotympanum in the guinea pig. Eur Arch Otorhinolaryngol. 1995;252:35-41.
-
(1995)
Eur Arch Otorhinolaryngol
, vol.252
, pp. 35-41
-
-
Ohashi, Y.1
Nakai, Y.2
Ohno, Y.3
-
53
-
-
0036218269
-
Effect of bacterial endotoxin and middle ear effusion on ciliary activity: Implications for otitis media
-
12150522
-
Mason P, Adam E, Prior M, et al. Effect of bacterial endotoxin and middle ear effusion on ciliary activity: implications for otitis media. The Laryngoscope. 2002;112:676-80.
-
(2002)
The Laryngoscope
, vol.112
, pp. 676-680
-
-
Mason, P.1
Adam, E.2
Prior, M.3
-
54
-
-
0026552207
-
Ciliary beat frequency of nasal and middle ear mucosa in children with otitis media with effusion
-
1587032 1:STN:280:DyaK383ms1KjsA%3D%3D
-
Wake M, Smallman L. Ciliary beat frequency of nasal and middle ear mucosa in children with otitis media with effusion. Clinical Otolaryngology and Allied Sciences. 1992;17:155-7.
-
(1992)
Clinical Otolaryngology and Allied Sciences
, vol.17
, pp. 155-157
-
-
Wake, M.1
Smallman, L.2
-
55
-
-
0032842838
-
Eya1-deficient mice lack ears and kidneys and show abnormal apoptosis of organ primordia
-
10471511 1:CAS:528:DyaK1MXlvFWht7k%3D
-
Xu P, Adams J, Peters H, et al. Eya1-deficient mice lack ears and kidneys and show abnormal apoptosis of organ primordia. Nat Genet. 1999;23:113-7.
-
(1999)
Nat Genet
, vol.23
, pp. 113-117
-
-
Xu, P.1
Adams, J.2
Peters, H.3
-
56
-
-
38849181806
-
Eya4-deficient mice are a model for heritable otitis media
-
18219393 1:CAS:528:DC%2BD1cXhsFOms78%3D
-
Depreux F, Darrow K, Conner D, et al. Eya4-deficient mice are a model for heritable otitis media. J Clin Invest. 2008;118:651-8.
-
(2008)
J Clin Invest
, vol.118
, pp. 651-658
-
-
Depreux, F.1
Darrow, K.2
Conner, D.3
-
57
-
-
67749099300
-
Regulation of the innate immune response by threonine-phosphatase of Eyes absent
-
19561593 1:CAS:528:DC%2BD1MXnslKqtLk%3D
-
Okabe Y, Sano T, Nagata S. Regulation of the innate immune response by threonine-phosphatase of Eyes absent. Nature. 2009;460:520-4.
-
(2009)
Nature
, vol.460
, pp. 520-524
-
-
Okabe, Y.1
Sano, T.2
Nagata, S.3
-
58
-
-
4944228028
-
A comparative study of Eya1 and Eya4 protein function and its implication in branchio-oto-renal syndrome and DFNA10
-
15492887
-
Zhang Y, Knosp B, Maconochie M, et al. A comparative study of Eya1 and Eya4 protein function and its implication in branchio-oto-renal syndrome and DFNA10. JARO. 2004;5:295-304.
-
(2004)
JARO
, vol.5
, pp. 295-304
-
-
Zhang, Y.1
Knosp, B.2
Maconochie, M.3
-
59
-
-
0035253743
-
Mutations in the transcriptional activator EYA4 cause late-onset deafness at the DFNA10 locus
-
11159937 1:CAS:528:DC%2BD3MXht1Sktbw%3D
-
Wayne S, Robertson N, DeClau F, et al. Mutations in the transcriptional activator EYA4 cause late-onset deafness at the DFNA10 locus. Hum Mol Genet. 2001;10:195-200.
-
(2001)
Hum Mol Genet
, vol.10
, pp. 195-200
-
-
Wayne, S.1
Robertson, N.2
Declau, F.3
-
60
-
-
34447283304
-
A novel splice site mutation in EYA4 causes DFNA10 hearing loss
-
17568404 1:CAS:528:DC%2BD2sXosF2jsLs%3D
-
Hildebrand M, Coman D, Yang T, et al. A novel splice site mutation in EYA4 causes DFNA10 hearing loss. Am J Med Genet. 2007;143A:1599-604.
-
(2007)
Am J Med Genet
, vol.143
, pp. 1599-1604
-
-
Hildebrand, M.1
Coman, D.2
Yang, T.3
-
61
-
-
0036821572
-
A 4-bp insertion in the eya-homologous region (eyaHR) of EYA4 causes hearing impairment in a Hungarian family linked to DFNA10
-
12477971 1:CAS:528:DC%2BD38Xps1OltL0%3D
-
Pfister M, Tóth T, Thiele H, et al. A 4-bp insertion in the eya-homologous region (eyaHR) of EYA4 causes hearing impairment in a Hungarian family linked to DFNA10. Mol Med. 2002;8:607-11.
-
(2002)
Mol Med
, vol.8
, pp. 607-611
-
-
Pfister, M.1
Tóth, T.2
Thiele, H.3
-
62
-
-
0029874138
-
The NF-kappa B and i kappa B proteins: New discoveries and insights
-
8717528 1:CAS:528:DyaK28XitlCgtbc%3D
-
Baldwin A. The NF-kappa B and I kappa B proteins: new discoveries and insights. Annu Rev Immunol. 1996;14:649-83.
-
(1996)
Annu Rev Immunol
, vol.14
, pp. 649-683
-
-
Baldwin, A.1
-
63
-
-
33750442875
-
Mutation at the Evi1 locus in Junbo mice causes susceptibility to otitis media
-
Parkinson N, Hardisty-Hughes R, Tateossian H, et al. Mutation at the Evi1 locus in Junbo mice causes susceptibility to otitis media. PLoS Genetics. 2006;2(10).
-
(2006)
PLoS Genetics
, vol.2
, Issue.10
-
-
Parkinson, N.1
Hardisty-Hughes, R.2
Tateossian, H.3
-
64
-
-
0034740688
-
Requirement of NF-kappaB/Rel for the development of hair follicles and other epidermal appendices
-
11585809 1:CAS:528:DC%2BD3MXnvVejs7Y%3D
-
Schmidt-Ullrich R, Aebischer T, Hülsken J, et al. Requirement of NF-kappaB/Rel for the development of hair follicles and other epidermal appendices. Development. 2001;128:3843-53.
-
(2001)
Development
, vol.128
, pp. 3843-3853
-
-
Schmidt-Ullrich, R.1
Aebischer, T.2
Hülsken, J.3
-
65
-
-
21244495232
-
Repression of bone morphogenetic protein and activin-inducible transcription by Evi-1
-
15849193 1:CAS:528:DC%2BD2MXltlKgs7o%3D
-
Alliston T, Ko T, Cao Y, et al. Repression of bone morphogenetic protein and activin-inducible transcription by Evi-1. J Biol Chem. 2005;280:24227-37.
-
(2005)
J Biol Chem
, vol.280
, pp. 24227-24237
-
-
Alliston, T.1
Ko, T.2
Cao, Y.3
-
66
-
-
0035353203
-
The corepressor CtBP interacts with Evi-1 to repress transforming growth factor beta signaling
-
11313276 1:CAS:528:DC%2BD3MXjtlShsr0%3D
-
Izutsu K, Kurokawa M, Imai Y, et al. The corepressor CtBP interacts with Evi-1 to repress transforming growth factor beta signaling. Blood. 2001;97:2815-22.
-
(2001)
Blood
, vol.97
, pp. 2815-2822
-
-
Izutsu, K.1
Kurokawa, M.2
Imai, Y.3
-
67
-
-
0034660525
-
The evi-1 oncoprotein inhibits c-Jun N-terminal kinase and prevents stress-induced cell death
-
10856240 1:CAS:528:DC%2BD3cXmtFCqs78%3D
-
Kurokawa M, Mitani K, Yamagata T, et al. The evi-1 oncoprotein inhibits c-Jun N-terminal kinase and prevents stress-induced cell death. EMBO J. 2000;19:2958-68.
-
(2000)
EMBO J
, vol.19
, pp. 2958-2968
-
-
Kurokawa, M.1
Mitani, K.2
Yamagata, T.3
-
68
-
-
84862627867
-
EVI1 acts as an inducible negative-feedback regulator of NF-κB by inhibiting p65 acetylation
-
22581859 1:CAS:528:DC%2BC38XotFGru78%3D The authors have shown a novel role for Evi1 in regulating NFkB. A mutation within Evi1 is the cause of the OM phenotype observed in Junbo, and this research provides additional information regarding the role this mutation plays in this chronic OM mouse model
-
• Xu X, Woo C-H, Steere R, et al. EVI1 acts as an inducible negative-feedback regulator of NF-κB by inhibiting p65 acetylation. J Immunol. 2012;188:6371-80. The authors have shown a novel role for Evi1 in regulating NFkB. A mutation within Evi1 is the cause of the OM phenotype observed in Junbo, and this research provides additional information regarding the role this mutation plays in this chronic OM mouse model.
-
(2012)
J Immunol
, vol.188
, pp. 6371-6380
-
-
Xu, X.1
Woo, C.-H.2
Steere, R.3
-
69
-
-
0037634002
-
The deaf mouse mutant Jeff (Jf) is a single gene model of otitis media
-
12943368
-
Hardisty R, Erven A, Logan K, et al. The deaf mouse mutant Jeff (Jf) is a single gene model of otitis media. JARO. 2003;4:130-8.
-
(2003)
JARO
, vol.4
, pp. 130-138
-
-
Hardisty, R.1
Erven, A.2
Logan, K.3
-
70
-
-
84878941505
-
Otitis media in the Tgif knockout mouse implicates TGFβ signalling in chronic middle ear inflammatory disease
-
Ahead of print. This paper further supports the role of TGFβ signalling in OM pathogenesis
-
• Tateossian H, Morse S, Parker A, et al. Otitis media in the Tgif knockout mouse implicates TGFβ signalling in chronic middle ear inflammatory disease. Hum Mol Genet. 2013. Ahead of print. This paper further supports the role of TGFβ signalling in OM pathogenesis.
-
(2013)
Hum Mol Genet
-
-
Tateossian, H.1
Morse, S.2
Parker, A.3
-
71
-
-
77953695161
-
Cellular and molecular basis for the regulation of inflammation by TGF-beta
-
20410014 1:CAS:528:DC%2BC3cXmslSlsro%3D
-
Yoshimura A, Wakabayashi Y, Mori T, et al. Cellular and molecular basis for the regulation of inflammation by TGF-beta. J Biochem. 2010;147:781-92.
-
(2010)
J Biochem
, vol.147
, pp. 781-792
-
-
Yoshimura, A.1
Wakabayashi, Y.2
Mori, T.3
-
72
-
-
33646164362
-
Transforming growth factor-beta regulation of immune responses
-
16551245 1:CAS:528:DC%2BD28XkvFSqt7w%3D
-
Li M, Wan Y, Sanjabi S, et al. Transforming growth factor-beta regulation of immune responses. Annu Rev Immunol. 2006;24:99-146.
-
(2006)
Annu Rev Immunol
, vol.24
, pp. 99-146
-
-
Li, M.1
Wan, Y.2
Sanjabi, S.3
-
73
-
-
0031438047
-
TGF-beta signalling from cell membrane to nucleus through SMAD proteins
-
9393997 1:CAS:528:DyaK2sXnvFyrtLo%3D
-
Heldin C, Miyazono K, ten Dijke P. TGF-beta signalling from cell membrane to nucleus through SMAD proteins. Nature. 1997;390:465-71.
-
(1997)
Nature
, vol.390
, pp. 465-471
-
-
Heldin, C.1
Miyazono, K.2
Ten Dijke, P.3
-
74
-
-
33750394887
-
A mutation in the F-box gene, Fbxo11, causes otitis media in the Jeff mouse
-
17035249 1:CAS:528:DC%2BD28XhtFKlsbvN
-
Hardisty-Hughes R, Tateossian H, Morse S, et al. A mutation in the F-box gene, Fbxo11, causes otitis media in the Jeff mouse. Hum Mol Genet. 2006;15:3273-9.
-
(2006)
Hum Mol Genet
, vol.15
, pp. 3273-3279
-
-
Hardisty-Hughes, R.1
Tateossian, H.2
Morse, S.3
-
75
-
-
79959469863
-
Regulation of cell fate determination by Skp1-Cullin1-F-box (SCF) E3 ubiquitin ligases
-
21710433 1:CAS:528:DC%2BC3MXht12ktbbI
-
Hindley C, McDowell G, Wise H, et al. Regulation of cell fate determination by Skp1-Cullin1-F-box (SCF) E3 ubiquitin ligases. Int J Dev Biol. 2011;55:249-60.
-
(2011)
Int J Dev Biol
, vol.55
, pp. 249-260
-
-
Hindley, C.1
McDowell, G.2
Wise, H.3
-
76
-
-
33847328747
-
FBXO11 promotes the Neddylation of p53 and inhibits its transcriptional activity
-
17098746 1:CAS:528:DC%2BD2sXkvFekuw%3D%3D
-
Abida W, Nikolaev A, Zhao W, et al. FBXO11 promotes the Neddylation of p53 and inhibits its transcriptional activity. J Biol Chem. 2007;282:1797-804.
-
(2007)
J Biol Chem
, vol.282
, pp. 1797-1804
-
-
Abida, W.1
Nikolaev, A.2
Zhao, W.3
-
77
-
-
0038274163
-
Links between tumor suppressors: P53 is required for TGF-beta gene responses by cooperating with Smads
-
12732139 1:CAS:528:DC%2BD3sXjslOltbc%3D
-
Cordenonsi M, Dupont S, Maretto S, et al. Links between tumor suppressors: p53 is required for TGF-beta gene responses by cooperating with Smads. Cell. 2003;113:301-14.
-
(2003)
Cell
, vol.113
, pp. 301-314
-
-
Cordenonsi, M.1
Dupont, S.2
Maretto, S.3
-
78
-
-
79751538604
-
Regulation of TGF-beta signalling by Fbxo11, the gene mutated in the Jeff otitis media mouse mutant
-
19580641
-
Tateossian H, Hardisty-Hughes R, Morse S, et al. Regulation of TGF-beta signalling by Fbxo11, the gene mutated in the Jeff otitis media mouse mutant. Pathogenetics. 2009;2:5.
-
(2009)
Pathogenetics
, vol.2
, pp. 5
-
-
Tateossian, H.1
Hardisty-Hughes, R.2
Morse, S.3
-
79
-
-
0033515620
-
A Smad transcriptional corepressor
-
10199400 1:CAS:528:DyaK1MXitlGmt7Y%3D
-
Wotton D, Lo R, Lee S, et al. A Smad transcriptional corepressor. Cell. 1999;97:29-39.
-
(1999)
Cell
, vol.97
, pp. 29-39
-
-
Wotton, D.1
Lo, R.2
Lee, S.3
-
80
-
-
33747174594
-
Nuclear retention of the tumor suppressor cPML by the homeodomain protein TGIF restricts TGF-beta signaling
-
16916642 1:CAS:528:DC%2BD28Xpt1Snur8%3D
-
Seo S, Ferrand N, Faresse N, et al. Nuclear retention of the tumor suppressor cPML by the homeodomain protein TGIF restricts TGF-beta signaling. Molecular Cell. 2006;23:547-59.
-
(2006)
Molecular Cell
, vol.23
, pp. 547-559
-
-
Seo, S.1
Ferrand, N.2
Faresse, N.3
-
81
-
-
35148892160
-
Genetic polymorphisms in immunoresponse genes TNFA, IL6, IL10, and TLR4 are associated with recurrent acute otitis media
-
17908769
-
Emonts M, Veenhoven R, Wiertsema S, et al. Genetic polymorphisms in immunoresponse genes TNFA, IL6, IL10, and TLR4 are associated with recurrent acute otitis media. Pediatrics. 2007;120:814-23.
-
(2007)
Pediatrics
, vol.120
, pp. 814-823
-
-
Emonts, M.1
Veenhoven, R.2
Wiertsema, S.3
-
82
-
-
73449145010
-
Toll-like receptors 2 and 4 and their mutations in patients with otitis media and middle ear effusion
-
19434266
-
Lee Y, Kim C, Shim J, et al. Toll-like receptors 2 and 4 and their mutations in patients with otitis media and middle ear effusion. Clinical and Experimental Otorhinolaryngology. 2008;1:189-95.
-
(2008)
Clinical and Experimental Otorhinolaryngology
, vol.1
, pp. 189-195
-
-
Lee, Y.1
Kim, C.2
Shim, J.3
-
83
-
-
33746109994
-
Association of the FBXO11 gene with chronic otitis media with effusion and recurrent otitis media: The Minnesota COME/ROM Family Study
-
16847180
-
Segade F, Daly K, Allred D, et al. Association of the FBXO11 gene with chronic otitis media with effusion and recurrent otitis media: the Minnesota COME/ROM Family Study. Arch Otolaryngol Head Neck Surg. 2006;132:729-33.
-
(2006)
Arch Otolaryngol Head Neck Surg
, vol.132
, pp. 729-733
-
-
Segade, F.1
Daly, K.2
Allred, D.3
-
84
-
-
79960618956
-
FBXO11, a regulator of the TGFβ pathway, is associated with severe otitis media in Western Australian children
-
21293382 1:CAS:528:DC%2BC3MXpt1akt7s%3D This paper demonstrates an association for mutations in FBXO11 in the human population for susceptibility to OM. Fbxo11 was discovered as the causative gene in the Jeff mouse model of chronic OM
-
• Rye M, Wiertsema S, Scaman E, et al. FBXO11, a regulator of the TGFβ pathway, is associated with severe otitis media in Western Australian children. Genes and Immunity. 2011;12:352-9. This paper demonstrates an association for mutations in FBXO11 in the human population for susceptibility to OM. Fbxo11 was discovered as the causative gene in the Jeff mouse model of chronic OM.
-
(2011)
Genes and Immunity
, vol.12
, pp. 352-359
-
-
Rye, M.1
Wiertsema, S.2
Scaman, E.3
-
85
-
-
8844264507
-
Chronic and recurrent otitis media: A genome scan for susceptibility loci
-
15514890 1:CAS:528:DC%2BD2cXhtVegsrnI
-
Daly K, Brown W, Segade F, et al. Chronic and recurrent otitis media: a genome scan for susceptibility loci. Am J Hum Genet. 2004;75:988-97.
-
(2004)
Am J Hum Genet
, vol.75
, pp. 988-997
-
-
Daly, K.1
Brown, W.2
Segade, F.3
-
86
-
-
0036255811
-
Candidate-gene approaches for studying complex genetic traits: Practical considerations
-
11988764 1:CAS:528:DC%2BD38Xjs1yhtb4%3D
-
Tabor H, Risch N, Myers R. Candidate-gene approaches for studying complex genetic traits: practical considerations. Nat Rev Genet. 2002;3:391-7.
-
(2002)
Nat Rev Genet
, vol.3
, pp. 391-397
-
-
Tabor, H.1
Risch, N.2
Myers, R.3
-
87
-
-
80055091327
-
HIF-VEGF pathways are critical for chronic otitis media in Junbo and Jeff mouse mutants
-
Cheeseman M, Tyrer H, Williams D, et al. HIF-VEGF pathways are critical for chronic otitis media in Junbo and Jeff mouse mutants. PLoS Genetics. 2011;7.
-
(2011)
PLoS Genetics
, vol.7
-
-
Cheeseman, M.1
Tyrer, H.2
Williams, D.3
-
88
-
-
0242361669
-
A mouse model for acute otitis media
-
14616553
-
Melhus A, Ryan A. A mouse model for acute otitis media. APMIS. 2003;111:989-94.
-
(2003)
APMIS
, vol.111
, pp. 989-994
-
-
Melhus, A.1
Ryan, A.2
-
89
-
-
0037669010
-
Low conservation of alternative splicing patterns in the human and mouse genomes
-
12761046 1:CAS:528:DC%2BD3sXkt1WrurY%3D
-
Nurtdinov R, Artamonova I, Mironov A, et al. Low conservation of alternative splicing patterns in the human and mouse genomes. Hum Mol Genet. 2003;12:1313-20.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 1313-1320
-
-
Nurtdinov, R.1
Artamonova, I.2
Mironov, A.3
-
90
-
-
0037329757
-
Mutagenesis strategies for identifying novel loci associated with disease phenotypes
-
12524003 1:CAS:528:DC%2BD3sXnvFaj
-
Brown S, Hardisty R. Mutagenesis strategies for identifying novel loci associated with disease phenotypes. Seminars in Cell and Developmental Biology. 2003;14:19-24.
-
(2003)
Seminars in Cell and Developmental Biology
, vol.14
, pp. 19-24
-
-
Brown, S.1
Hardisty, R.2
-
91
-
-
33748567767
-
The relevance of genetically altered mouse models of human disease
-
16945009 1:CAS:528:DC%2BD28XpvVCqs70%3D
-
Bhogal N, Combes R. The relevance of genetically altered mouse models of human disease. ATLA. 2006;34:429-54.
-
(2006)
ATLA
, vol.34
, pp. 429-454
-
-
Bhogal, N.1
Combes, R.2
-
92
-
-
33746895469
-
C3H/HeJ mouse model for spontaneous chronic otitis media
-
16826039
-
MacArthur C, Hefeneider S, Kempton J, Trune D. C3H/HeJ mouse model for spontaneous chronic otitis media. The Laryngoscope. 2006;116(7):1071-9.
-
(2006)
The Laryngoscope
, vol.116
, Issue.7
, pp. 1071-1079
-
-
Macarthur, C.1
Hefeneider, S.2
Kempton, J.3
Trune, D.4
-
93
-
-
69949182416
-
The toll-Like receptor adaptor TRIF contributes to otitis media pathogenesis and recovery
-
19656404
-
Leichtle A, Hernandez M, Pak K, et al. The toll-Like receptor adaptor TRIF contributes to otitis media pathogenesis and recovery. BMC immunology. 2009;10:45.
-
(2009)
BMC Immunology
, vol.10
, pp. 45
-
-
Leichtle, A.1
Hernandez, M.2
Pak, K.3
-
94
-
-
24944577490
-
The role of Fas-mediated apoptosis in otitis media: Observations in the lpr/lpr mouse
-
1:CAS:528:DC%2BD2MXhtVSmsLvI
-
Rivkin A, Palacios S, Pak K, et al. The role of Fas-mediated apoptosis in otitis media: observations in the lpr/lpr mouse. Hearing Res. 2005;207(1-2):110-6.
-
(2005)
Hearing Res
, vol.207
, Issue.1-2
, pp. 110-116
-
-
Rivkin, A.1
Palacios, S.2
Pak, K.3
-
95
-
-
77951905332
-
CC chemokine ligand 3 overcomes the bacteriocidal and phagocytic defect of macrophages and hastens recovery from experimental otitis media in TNF-/- mice
-
20164426 1:CAS:528:DC%2BC3cXis1yitr0%3D
-
Leichtle A, Hernandez M, Ebmeyer J, et al. CC chemokine ligand 3 overcomes the bacteriocidal and phagocytic defect of macrophages and hastens recovery from experimental otitis media in TNF-/- mice. J Immunol. 2010;184(6):3087-97.
-
(2010)
J Immunol
, vol.184
, Issue.6
, pp. 3087-3097
-
-
Leichtle, A.1
Hernandez, M.2
Ebmeyer, J.3
-
96
-
-
79251543337
-
TNFA deletion alters apoptosis as well as caspase 3 and 4 expression during otitis media
-
21269505 1:CAS:528:DC%2BC3MXhslamu74%3D
-
Ebmeyer J, Leichtle A, Hernandez M, et al. TNFA deletion alters apoptosis as well as caspase 3 and 4 expression during otitis media. BMC immunology. 2011;12:12.
-
(2011)
BMC Immunology
, vol.12
, pp. 12
-
-
Ebmeyer, J.1
Leichtle, A.2
Hernandez, M.3
-
97
-
-
42049086290
-
Tumor suppressor CYLD acts as a negative regulator for non-typeable Haemophilus influenza-induced inflammation in the middle ear and lung of mice
-
Lim J, Jono H, Koga T, et al. Tumor suppressor CYLD acts as a negative regulator for non-typeable Haemophilus influenza-induced inflammation in the middle ear and lung of mice. PloS ONE. 2007;2(10).
-
(2007)
PloS ONE
, vol.2
, Issue.10
-
-
Lim, J.1
Jono, H.2
Koga, T.3
-
98
-
-
52449083975
-
Interleukin-10 is an essential modulator of mucoid metaplasia in a mouse otitis media model
-
18771082
-
Tsuchiya K, Komori M, Zheng Q, et al. Interleukin-10 is an essential modulator of mucoid metaplasia in a mouse otitis media model. Ann Otol Rhinol Laryngol. 2008;117(8):630-6.
-
(2008)
Ann Otol Rhinol Laryngol
, vol.117
, Issue.8
, pp. 630-636
-
-
Tsuchiya, K.1
Komori, M.2
Zheng, Q.3
-
99
-
-
84855363795
-
Congenital hydrocephalus in genetically engineered mice
-
21746835 1:STN:280:DC%2BC387hsVGrsA%3D%3D
-
Vogel P, Read R, Hansen G, et al. Congenital hydrocephalus in genetically engineered mice. Vet Pathol. 2012;49(1):166-81.
-
(2012)
Vet Pathol
, vol.49
, Issue.1
, pp. 166-181
-
-
Vogel, P.1
Read, R.2
Hansen, G.3
-
100
-
-
84856093088
-
Coordinated ciliary beating requires Odf2-mediated polarization of basal bodies via basal feet
-
22265411 1:CAS:528:DC%2BC38XhtFKgsLo%3D
-
Kunimoto K, Yamazaki Y, Nishida T, et al. Coordinated ciliary beating requires Odf2-mediated polarization of basal bodies via basal feet. Cell. 2012;148(1-2):189-200.
-
(2012)
Cell
, vol.148
, Issue.1-2
, pp. 189-200
-
-
Kunimoto, K.1
Yamazaki, Y.2
Nishida, T.3
-
101
-
-
77954916671
-
Tubulin tyrosine ligase-like 1 deficiency results in chronic rhinosinusitis and abnormal development of spermatid flagella in mice
-
20442420 1:CAS:528:DC%2BC3cXpsFSjt78%3D
-
Vogel P, Hansen G, Fontenot G, Read R. Tubulin tyrosine ligase-like 1 deficiency results in chronic rhinosinusitis and abnormal development of spermatid flagella in mice. Vet Pathol. 2010;47(4):703-12.
-
(2010)
Vet Pathol
, vol.47
, Issue.4
, pp. 703-712
-
-
Vogel, P.1
Hansen, G.2
Fontenot, G.3
Read, R.4
-
102
-
-
84865837413
-
Otitis media in a new mouse model for CHARGE syndrome with a deletion in the Chd7 gene
-
Tian C, Yu H, Yang B, et al. Otitis media in a new mouse model for CHARGE syndrome with a deletion in the Chd7 gene. PloS ONE. 2012;7(4).
-
(2012)
PloS ONE
, vol.7
, Issue.4
-
-
Tian, C.1
Yu, H.2
Yang, B.3
-
103
-
-
78650189252
-
Mice lacking adrenergic signaling have normal cochlear responses and normal resistance to acoustic injury but enhanced susceptibility to middle-ear infection
-
20503062
-
Maison S, Le M, Larsen E, et al. Mice lacking adrenergic signaling have normal cochlear responses and normal resistance to acoustic injury but enhanced susceptibility to middle-ear infection. JARO. 2010;11(3):449-61.
-
(2010)
JARO
, vol.11
, Issue.3
, pp. 449-461
-
-
Maison, S.1
Le, M.2
Larsen, E.3
-
104
-
-
0348191246
-
E2F4 is essential for normal erythrocyte maturation and neonatal viability
-
10983976 1:CAS:528:DC%2BD3cXmsFWmsb8%3D
-
Humbert P, Rogers C, Ganiatsas S, et al. E2F4 is essential for normal erythrocyte maturation and neonatal viability. Molecular Cell. 2000;6(2):281-91.
-
(2000)
Molecular Cell
, vol.6
, Issue.2
, pp. 281-291
-
-
Humbert, P.1
Rogers, C.2
Ganiatsas, S.3
-
105
-
-
11844262678
-
Hush puppy: A new mouse mutant with pinna, ossicle, and inner ear defects
-
15630379
-
Pau H, Fuchs H, de Angelis M, Steel K. Hush puppy: a new mouse mutant with pinna, ossicle, and inner ear defects. The Laryngoscope. 2005;115(1):116-24.
-
(2005)
The Laryngoscope
, vol.115
, Issue.1
, pp. 116-124
-
-
Pau, H.1
Fuchs, H.2
De Angelis, M.3
Steel, K.4
-
106
-
-
80051553050
-
A missense mutation in Fgfr1 causes ear and skull defects in hush puppy mice
-
21479780
-
Calvert J, Dedos S, Hawker K, et al. A missense mutation in Fgfr1 causes ear and skull defects in hush puppy mice. Mamm Genome. 2011;22(5-6):290-305.
-
(2011)
Mamm Genome
, vol.22
, Issue.5-6
, pp. 290-305
-
-
Calvert, J.1
Dedos, S.2
Hawker, K.3
-
107
-
-
80052835338
-
Exome sequencing identifies a missense mutation in Isl1 associated with low penetrance otitis media in dearisch mice
-
Hilton J, Lewis M, Grati Mh, et al. Exome sequencing identifies a missense mutation in Isl1 associated with low penetrance otitis media in dearisch mice. Genome Biol. 2011;12(9).
-
(2011)
Genome Biol
, vol.12
, Issue.9
-
-
Hilton, J.1
Lewis, M.2
Mh, G.3
-
108
-
-
84865204085
-
Pathological features in the LmnaDhe/+ mutant mouse provide a novel model of human otitis media and laminopathies
-
22819531 1:CAS:528:DC%2BC38XhsFSns7zJ
-
Zhang Y, Yu H, Xu M, et al. Pathological features in the LmnaDhe/+ mutant mouse provide a novel model of human otitis media and laminopathies. Am J Pathol. 2012;181(3):761-74.
-
(2012)
Am J Pathol
, vol.181
, Issue.3
, pp. 761-774
-
-
Zhang, Y.1
Yu, H.2
Xu, M.3
-
109
-
-
84874892781
-
Mcph1-Deficient Mice Reveal a Role for MCPH1 in Otitis Media
-
Chen J, Ingham N, Clare S, et al. Mcph1-Deficient Mice Reveal a Role for MCPH1 in Otitis Media. PloS ONE. 2013;8(3).
-
(2013)
PloS ONE
, vol.8
, Issue.3
-
-
Chen, J.1
Ingham, N.2
Clare, S.3
-
110
-
-
0034234894
-
Conditional biallelic Nf2 mutation in the mouse promotes manifestations of human neurofibromatosis type 2
-
10887156 1:CAS:528:DC%2BD3cXkvFCku7s%3D
-
Giovannini M, Robanus-Maandag E, van der Valk M, et al. Conditional biallelic Nf2 mutation in the mouse promotes manifestations of human neurofibromatosis type 2. Genes Dev. 2000;14(13):1617-30.
-
(2000)
Genes Dev
, vol.14
, Issue.13
, pp. 1617-1630
-
-
Giovannini, M.1
Robanus-Maandag, E.2
Van Der Valk, M.3
-
111
-
-
84871494595
-
A novel model of spontaneous otitis media with effusion (OME) in the Oxgr1 knock-out mouse
-
23200873
-
Kerschner J, Hong W, Taylor S, et al. A novel model of spontaneous otitis media with effusion (OME) in the Oxgr1 knock-out mouse. Int J Pediatr Otorhinolaryngol. 2013;77(1):79-84.
-
(2013)
Int J Pediatr Otorhinolaryngol
, vol.77
, Issue.1
, pp. 79-84
-
-
Kerschner, J.1
Hong, W.2
Taylor, S.3
-
112
-
-
17544363909
-
P73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours
-
10716451 1:CAS:528:DC%2BD3cXhvVyqtbo%3D
-
Yang A, Walker N, Bronson R, et al. p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours. Nature. 2000;404(6773):99-103.
-
(2000)
Nature
, vol.404
, Issue.6773
, pp. 99-103
-
-
Yang, A.1
Walker, N.2
Bronson, R.3
-
113
-
-
40049106361
-
A mouse model with postnatal endolymphatic hydrops and hearing loss
-
1:CAS:528:DC%2BD1cXjtVSqtrg%3D
-
Megerian C, Semaan M, Aftab S, et al. A mouse model with postnatal endolymphatic hydrops and hearing loss. Hearing Res. 2008;237(1-2):90-105.
-
(2008)
Hearing Res
, vol.237
, Issue.1-2
, pp. 90-105
-
-
Megerian, C.1
Semaan, M.2
Aftab, S.3
-
114
-
-
84866996749
-
Mutation in Phex gene predisposes BALB/c-Phex(Hyp-Duk)/Y mice to otitis media
-
Han F, Yu H, Li P, et al. Mutation in Phex gene predisposes BALB/c-Phex(Hyp-Duk)/Y mice to otitis media. PloS ONE. 2012;7(9).
-
(2012)
PloS ONE
, vol.7
, Issue.9
-
-
Han, F.1
Yu, H.2
Li, P.3
-
115
-
-
33750007162
-
Spontaneous development of otitis media in plasminogen-deficient mice
-
16956791
-
Eriksson P-O, Li J, Ny T, Hellström S. Spontaneous development of otitis media in plasminogen-deficient mice. IJMM. 2006;296(7):501-9.
-
(2006)
IJMM
, vol.296
, Issue.7
, pp. 501-509
-
-
Eriksson, P.-O.1
Li, J.2
Ny, T.3
Hellström, S.4
-
116
-
-
78951488484
-
Ectopic mineralization in the middle ear and chronic otitis media with effusion caused by RPL38 deficiency in the Tail-short (Ts) mouse
-
21062742 1:CAS:528:DC%2BC3MXosVeitA%3D%3D
-
Noben-Trauth K, Latoche J. Ectopic mineralization in the middle ear and chronic otitis media with effusion caused by RPL38 deficiency in the Tail-short (Ts) mouse. J Biol Chem. 2011;286(4):3079-93.
-
(2011)
J Biol Chem
, vol.286
, Issue.4
, pp. 3079-3093
-
-
Noben-Trauth, K.1
Latoche, J.2
-
117
-
-
33846809132
-
A Sall4 mutant mouse model useful for studying the role of Sall4 in early embryonic development and organogenesis
-
17216607 1:CAS:528:DC%2BD2sXit1aju7w%3D
-
Warren M, Wang W, Spiden S, et al. A Sall4 mutant mouse model useful for studying the role of Sall4 in early embryonic development and organogenesis. Genesis. 2007;45(1):51-8.
-
(2007)
Genesis
, vol.45
, Issue.1
, pp. 51-58
-
-
Warren, M.1
Wang, W.2
Spiden, S.3
-
118
-
-
70349862721
-
The podosomal-adaptor protein SH3PXD2B is essential for normal postnatal development
-
19669234 1:CAS:528:DC%2BD1MXht1Cis7bP
-
Mao M, Thedens D, Chang B, et al. The podosomal-adaptor protein SH3PXD2B is essential for normal postnatal development. Mamm Genome. 2009;20(8):462-75.
-
(2009)
Mamm Genome
, vol.20
, Issue.8
, pp. 462-475
-
-
Mao, M.1
Thedens, D.2
Chang, B.3
-
119
-
-
79960766400
-
Sh3pxd2b mice are a model for craniofacial dysmorphology and otitis media
-
Yang B, Tian C, Zhang Z-g, et al. Sh3pxd2b mice are a model for craniofacial dysmorphology and otitis media. PloS ONE. 2011;6(7).
-
(2011)
PloS ONE
, vol.6
, Issue.7
-
-
Yang, B.1
Tian, C.2
|