메뉴 건너뛰기




Volumn 184, Issue 6, 2010, Pages 3087-3097

CC chemokine ligand 3 overcomes the bacteriocidal and phagocytic defect of macrophages and hastens recovery from experimental otitis media in TNF -/- mice

Author keywords

[No Author keywords available]

Indexed keywords

MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; RECOMBINANT TUMOR NECROSIS FACTOR; TOLL LIKE RECEPTOR; TUMOR NECROSIS FACTOR; AUTACOID; CCL3 PROTEIN, MOUSE; RECOMBINANT PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 77951905332     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0901167     Document Type: Article
Times cited : (40)

References (52)
  • 4
    • 0027818315 scopus 로고
    • Otitis media in children: Frequency, risk factors, and research avenues
    • Infante-Rivard, C., and A. Fernández. 1993. Otitis media in children: frequency, risk factors, and research avenues. Epidemiol. Rev. 15: 444-465.
    • (1993) Epidemiol. Rev. , vol.15 , pp. 444-465
    • Infante-Rivard, C.1    Fernández, A.2
  • 5
    • 0030949052 scopus 로고    scopus 로고
    • Are antibiotics indicated as initial treatment for children with acute otitis media? a meta-analysis
    • Del Mar, C., P. Glasziou, and M. Hayem. 1997. Are antibiotics indicated as initial treatment for children with acute otitis media? A meta-analysis. BMJ 314: 1526-1529. (Pubitemid 27216070)
    • (1997) British Medical Journal , vol.314 , Issue.7093 , pp. 1526-1529
    • Del Mar, C.1    Glasziou, P.2    Hayem, M.3
  • 6
    • 0034623898 scopus 로고    scopus 로고
    • The burden of otitis media
    • Klein, J. O. 2000. The burden of otitis media. Vaccine 19(Suppl 1): S2-S8.
    • (2000) Vaccine , vol.19 , Issue.SUPPL. 1
    • Klein, J.O.1
  • 7
    • 0033586383 scopus 로고    scopus 로고
    • Early surgery compared with watchful waiting for glue ear and effect on language development in preschool children: A randomised trial
    • DOI 10.1016/S0140-6736(98)05295-7
    • Maw, R., J. Wilks, I. Harvey, T. J. Peters, and J. Golding. 1999. Early surgery compared with watchful waiting for glue ear and effect on language development in preschool children: a randomised trial. Lancet 353: 960-963. (Pubitemid 29132604)
    • (1999) Lancet , vol.353 , Issue.9157 , pp. 960-963
    • Maw, R.1    Wilks, J.2    Harvey, I.3    Peters, T.J.4    Golding, J.5
  • 8
    • 0034919510 scopus 로고    scopus 로고
    • Behaviour and developmental effects of otitis media with effusion into the teens
    • Bennett, K. E., M. P. Haggard, P. A. Silva, and I. A. Stewart. 2001. Behaviour and developmental effects of otitis media with effusion into the teens. Arch. Dis. Child. 85: 91-95.
    • (2001) Arch. Dis. Child. , vol.85 , pp. 91-95
    • Bennett, K.E.1    Haggard, M.P.2    Silva, P.A.3    Stewart, I.A.4
  • 11
    • 35148892160 scopus 로고    scopus 로고
    • Genetic polymorphisms in immunoresponse genes TNFA, IL6, IL10, and TLR4 are associated with recurrent acute otitis media
    • DOI 10.1542/peds.2007-0524
    • Emonts, M., R. H. Veenhoven, S. P. Wiertsema, J. J. Houwing-Duistermaat, V. Walraven, R. de Groot, P. W. Hermans, and E. A. Sanders. 2007. Genetic polymorphisms in immunoresponse genes TNFA, IL6, IL10, and TLR4 are associated with recurrent acute otitis media. Pediatrics 120: 814-823. (Pubitemid 47549570)
    • (2007) Pediatrics , vol.120 , Issue.4 , pp. 814-823
    • Emonts, M.1    Veenhoven, R.H.2    Wiertsema, S.P.3    Houwing-Duistermaat, J.J.4    Walraven, V.5    De Groot, R.6    Hermans, P.W.M.7    Sanders, E.A.M.8
  • 15
    • 33748669853 scopus 로고    scopus 로고
    • Role of nontypeable Haemophilus influenzae in exacerbations and progression of chronic obstructive pulmonary disease
    • Eldika, N., and S. Sethi. 2006. Role of nontypeable Haemophilus influenzae in exacerbations and progression of chronic obstructive pulmonary disease. Curr. Opin. Pulm. Med. 12: 118-124.
    • (2006) Curr. Opin. Pulm. Med. , vol.12 , pp. 118-124
    • Eldika, N.1    Sethi, S.2
  • 16
    • 0032873619 scopus 로고    scopus 로고
    • Purification and characterization of outer membrane protein P6, a vaccine antigen of non-typeable Haemophilus influenzae
    • Karalus, R. J., and T. F. Murphy. 1999. Purification and characterization of outer membrane protein P6, a vaccine antigen of non-typeable Haemophilus influenzae. FEMS Immunol. Med. Microbiol. 26: 159-166.
    • (1999) FEMS Immunol. Med. Microbiol. , vol.26 , pp. 159-166
    • Karalus, R.J.1    Murphy, T.F.2
  • 17
    • 0026681608 scopus 로고
    • Outer membrane proteins and lipopolysaccharides of nontypeable Haemophilus influenzae
    • Barenkamp, S. J. 1992. Outer membrane proteins and lipopolysaccharides of nontypeable Haemophilus influenzae. J. Infect. Dis. 165(Suppl 1): S181-S184.
    • (1992) J. Infect. Dis. , vol.165 , Issue.SUPPL. 1
    • Barenkamp, S.J.1
  • 18
    • 0035902482 scopus 로고    scopus 로고
    • Activation of NF-κB by nontypeable Hemophilus influenzae is mediated by toll-like receptor 2-TAK1-dependent NIK-IKKα/β- IκBα and MKK3/6-p38 MAP kinase signaling pathways in epithelial cells
    • Shuto, T., H. Xu, B. Wang, J. Han, H. Kai, X. X. Gu, T. F. Murphy, D. J. Lim, and J. D. Li. 2001. Activation of NF-κB by nontypeable Hemophilus influenzae is mediated by toll-like receptor 2-TAK1-dependent NIK-IKKα/β-IκBα and MKK3/6-p38 MAP kinase signaling pathways in epithelial cells. Proc. Natl. Acad. Sci. U.S.A. 98: 8774-8779.
    • (2001) Proc. Natl. Acad. Sci. U.S.A. , vol.98 , pp. 8774-8779
    • Shuto, T.1    Xu, H.2    Wang, B.3    Han, J.4    Kai, H.5    Gu, X.X.6    Murphy, T.F.7    Lim, D.J.8    Li, J.D.9
  • 19
    • 0030610362 scopus 로고    scopus 로고
    • A cytokine-responsive IκB kinase that activates the transcription factor NF-κB
    • DiDonato, J. A., M. Hayakawa, D. M. Rothwarf, E. Zandi, and M. Karin. 1997. A cytokine-responsive IκB kinase that activates the transcription factor NF-κB. Nature 388: 548-554.
    • (1997) Nature , vol.388 , pp. 548-554
    • Didonato, J.A.1    Hayakawa, M.2    Rothwarf, D.M.3    Zandi, E.4    Karin, M.5
  • 20
    • 0033595893 scopus 로고    scopus 로고
    • How NF-κB is activated: The role of the IκB kinase (IKK) complex
    • Karin, M. 1999. How NF-κB is activated: the role of the IκB kinase (IKK) complex. Oncogene 18: 6867-6874.
    • (1999) Oncogene , vol.18 , pp. 6867-6874
    • Karin, M.1
  • 22
    • 0033975869 scopus 로고    scopus 로고
    • Innate immune recognition: Mechanisms and pathways
    • Medzhitov, R., and C. Janeway, Jr. 2000. Innate immune recognition: mechanisms and pathways. Immunol. Rev. 173: 89-97.
    • (2000) Immunol. Rev. , vol.173 , pp. 89-97
    • Medzhitov, R.1    Janeway Jr., C.2
  • 23
    • 38549102077 scopus 로고    scopus 로고
    • TNF-mediated inflammatory disease
    • Bradley, J. R. 2008. TNF-mediated inflammatory disease. J. Pathol. 214: 149-160.
    • (2008) J. Pathol. , vol.214 , pp. 149-160
    • Bradley, J.R.1
  • 24
    • 0025966918 scopus 로고
    • The response to human rIL-1, rIL-2 and rTNF in the middle ear of guinea pigs
    • Catanzaro, A., A. Ryan, S. Batcher, and S. I. Wasserman. 1991. The response to human rIL-1, rIL-2 and rTNF in the middle ear of guinea pigs. Laryngoscope 101: 271-275.
    • (1991) Laryngoscope , vol.101 , pp. 271-275
    • Catanzaro, A.1    Ryan, A.2    Batcher, S.3    Wasserman, S.I.4
  • 25
    • 0034769192 scopus 로고    scopus 로고
    • Effect of inhibitor of tumor necrosis factor-α on experimental otitis media with effusion
    • Jeon, E. J., Y. S. Park, Y. C. Choi, S. W. Yeo, and T. T. Jung. 2001. Effect of inhibitor of tumor necrosis factor-α on experimental otitis media with effusion. Ann. Otol. Rhinol. Laryngol. 110: 917-921.
    • (2001) Ann. Otol. Rhinol. Laryngol. , vol.110 , pp. 917-921
    • Jeon, E.J.1    Park, Y.S.2    Choi, Y.C.3    Yeo, S.W.4    Jung, T.T.5
  • 26
    • 0035071444 scopus 로고    scopus 로고
    • Effect of tumor necrosis factor-α on experimental otitis media with effusion
    • Lee, D. H., Y. S. Park, T. T. Jung, S. W. Yeo, Y. C. Choi, and E. Jeon. 2001. Effect of tumor necrosis factor-α on experimental otitis media with effusion. Laryngoscope 111: 728-733. (Pubitemid 32295292)
    • (2001) Laryngoscope , vol.111 , Issue.4 I , pp. 728-733
    • Lee, D.-H.1    Park, Y.-S.2    Jung, T.T.K.3    Yeo, S.-W.4    Choi, Y.-C.5    Jeon, E.-J.6
  • 27
    • 33747437643 scopus 로고    scopus 로고
    • Effects of tumor necrosis factor α antagonist, platelet activating factor antagonist, and nitric oxide synthase inhibitor on experimental otitis media with effusion
    • Kim, D. H., Y. S. Park, E. J. Jeon, S. W. Yeo, K. H. Chang, and S. K. Lee. 2006. Effects of tumor necrosis factor α antagonist, platelet activating factor antagonist, and nitric oxide synthase inhibitor on experimental otitis media with effusion. Ann. Otol. Rhinol. Laryngol. 115: 617-623.
    • (2006) Ann. Otol. Rhinol. Laryngol. , vol.115 , pp. 617-623
    • Kim, D.H.1    Park, Y.S.2    Jeon, E.J.3    Yeo, S.W.4    Chang, K.H.5    Lee, S.K.6
  • 28
    • 33748554172 scopus 로고    scopus 로고
    • Effect of inhibitor of tumor necrosis factor-α and oxatomide on immune mediated otitis media
    • Park, Y. S., H. J. Auo, E. J. Jeon, K. H. Chang, S. K. Lee, and D. H. Lee. 2006. Effect of inhibitor of tumor necrosis factor-α and oxatomide on immune mediated otitis media. Laryngoscope 116: 1642-1646.
    • (2006) Laryngoscope , vol.116 , pp. 1642-1646
    • Park, Y.S.1    Auo, H.J.2    Jeon, E.J.3    Chang, K.H.4    Lee, S.K.5    Lee, D.H.6
  • 29
    • 33947121641 scopus 로고    scopus 로고
    • Association of proinflammatory cytokine gene polymorphisms with susceptibility to otitis media
    • DOI 10.1542/peds.2006-0764
    • Patel, J. A., S. Nair, K. Revai, J. Grady, K. Saeed, R. Matalon, S. Block, and T. Chonmaitree. 2006. Association of proinflammatory cytokine gene polymorphisms with susceptibility to otitis media. Pediatrics 118: 2273-2279. (Pubitemid 46397564)
    • (2006) Pediatrics , vol.118 , Issue.6 , pp. 2273-2279
    • Patel, J.A.1    Nair, S.2    Revai, K.3    Grady, J.4    Saeed, K.5    Matalon, R.6    Block, S.7    Chonmaitree, T.8
  • 30
    • 57649223694 scopus 로고    scopus 로고
    • Cytokine polymorphisms predict the frequency of otitis media as a complication of rhinovirus and RSV infections in children
    • Alper, C. M., B. Winther, J. O. Hendley, and W. J. Doyle. 2009. Cytokine polymorphisms predict the frequency of otitis media as a complication of rhinovirus and RSV infections in children. Eur. Arch. Otorhinolaryngol. 266: 199-205.
    • (2009) Eur. Arch. Otorhinolaryngol. , vol.266 , pp. 199-205
    • Alper, C.M.1    Winther, B.2    Hendley, J.O.3    Doyle, W.J.4
  • 31
    • 4344561190 scopus 로고    scopus 로고
    • NF-κB is essential for induction of CYLD, the negative regulator of NF-κB: Evidence for a novel inducible autoregulatory feedback pathway
    • Jono, H., J. H. Lim, L. F. Chen, H. Xu, E. Trompouki, Z. K. Pan, G. Mosialos, and J. D. Li. 2004. NF-κB is essential for induction of CYLD, the negative regulator of NF-κB: evidence for a novel inducible autoregulatory feedback pathway. J. Biol. Chem. 279: 36171-36174.
    • (2004) J. Biol. Chem. , vol.279 , pp. 36171-36174
    • Jono, H.1    Lim, J.H.2    Chen, L.F.3    Xu, H.4    Trompouki, E.5    Pan, Z.K.6    Mosialos, G.7    Li, J.D.8
  • 32
    • 0036918679 scopus 로고    scopus 로고
    • An essential role of macrophage inflammatory protein 1α/CCL3 on the expression of host's innate immunities against infectious complications
    • Takahashi, H., T. Tashiro, M. Miyazaki, M. Kobayashi, R. B. Pollard, and F. Suzuki. 2002. An essential role of macrophage inflammatory protein 1α/CCL3 on the expression of host's innate immunities against infectious complications. J. Leukoc. Biol. 72: 1190-1197.
    • (2002) J. Leukoc. Biol. , vol.72 , pp. 1190-1197
    • Takahashi, H.1    Tashiro, T.2    Miyazaki, M.3    Kobayashi, M.4    Pollard, R.B.5    Suzuki, F.6
  • 33
    • 38349025503 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha (TNF-α) induces integrin CD11b/CD18 (Mac-1) up-regulation and migration to the CC chemokine CCL3 (MIP-1α) on human neutrophils through defined signalling pathways
    • Montecucco, F., S. Steffens, F. Burger, A. Da Costa, G. Bianchi, M. Bertolotto, F. Mach, F. Dallegri, and L. Ottonello. 2008. Tumor necrosis factor-alpha (TNF-α) induces integrin CD11b/CD18 (Mac-1) up-regulation and migration to the CC chemokine CCL3 (MIP-1α) on human neutrophils through defined signalling pathways. Cell. Signal. 20: 557-568.
    • (2008) Cell. Signal. , vol.20 , pp. 557-568
    • Montecucco, F.1    Steffens, S.2    Burger, F.3    Da Costa, A.4    Bianchi, G.5    Bertolotto, M.6    Mach, F.7    Dallegri, F.8    Ottonello, L.9
  • 35
    • 0024853541 scopus 로고
    • Myelopoietic enhancing effects of murine macrophage inflammatory proteins 1 and 2 on colony formation in vitro by murine and human bone marrow granulocyte/macrophage progenitor cells
    • Broxmeyer, H. E., B. Sherry, L. Lu, S. Cooper, C. Carow, S. D. Wolpe, and A. Cerami. 1989. Myelopoietic enhancing effects of murine macrophage inflammatory proteins 1 and 2 on colony formation in vitro by murine and human bone marrow granulocyte/macrophage progenitor cells. J. Exp. Med. 170: 1583-1594.
    • (1989) J. Exp. Med. , vol.170 , pp. 1583-1594
    • Broxmeyer, H.E.1    Sherry, B.2    Lu, L.3    Cooper, S.4    Carow, C.5    Wolpe, S.D.6    Cerami, A.7
  • 36
    • 0033213590 scopus 로고    scopus 로고
    • Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components
    • DOI 10.1016/S1074-7613(00)80119-3
    • Takeuchi, O., K. Hoshino, T. Kawai, H. Sanjo, H. Takada, T. Ogawa, K. Takeda, and S. Akira. 1999. Differential roles of TLR2 and TLR4 in recognition of gramnegative and gram-positive bacterial cell wall components. Immunity 11: 443-451. (Pubitemid 29504199)
    • (1999) Immunity , vol.11 , Issue.4 , pp. 443-451
    • Takeuchi, O.1    Hoshino, K.2    Kawai, T.3    Sanjo, H.4    Takada, H.5    Ogawa, T.6    Takeda, K.7    Akira, S.8
  • 37
    • 0242361669 scopus 로고    scopus 로고
    • A mouse model for acute otitis media
    • DOI 10.1034/j.1600-0463.2003.1111012.x
    • Melhus, A., and A. F. Ryan. 2003. A mouse model for acute otitis media. APMIS 111: 989-994. (Pubitemid 37352619)
    • (2003) APMIS , vol.111 , Issue.10 , pp. 989-994
    • Melhus, A.1    Ryan, A.F.2
  • 39
    • 2342525996 scopus 로고    scopus 로고
    • Regulation of phagosome maturation by signals from toll-like receptors
    • Blander, J. M., and R. Medzhitov. 2004. Regulation of phagosome maturation by signals from toll-like receptors. Science 304: 1014-1018.
    • (2004) Science , vol.304 , pp. 1014-1018
    • Blander, J.M.1    Medzhitov, R.2
  • 40
    • 27144477318 scopus 로고    scopus 로고
    • Cutting edge: MyD88 controls phagocyte NADPH oxidase function and killing of gramnegative bacteria
    • Laroux, F. S., X. Romero, L. Wetzler, P. Engel, and C. Terhorst. 2005. Cutting edge: MyD88 controls phagocyte NADPH oxidase function and killing of gramnegative bacteria. J. Immunol. 175: 5596-5600.
    • (2005) J. Immunol. , vol.175 , pp. 5596-5600
    • Laroux, F.S.1    Romero, X.2    Wetzler, L.3    Engel, P.4    Terhorst, C.5
  • 41
    • 0034670047 scopus 로고    scopus 로고
    • Gene expressions of Toll-like receptor 2, but not Toll-like receptor 4, is induced by LPS and inflammatory cytokines in mouse macrophages
    • Matsuguchi, T., T. Musikacharoen, T. Ogawa, and Y. Yoshikai. 2000. Gene expressions of Toll-like receptor 2, but not Toll-like receptor 4, is induced by LPS and inflammatory cytokines in mouse macrophages. J. Immunol. 165: 5767-5772.
    • (2000) J. Immunol. , vol.165 , pp. 5767-5772
    • Matsuguchi, T.1    Musikacharoen, T.2    Ogawa, T.3    Yoshikai, Y.4
  • 43
    • 0028305693 scopus 로고
    • The macrophage is an important and previously unrecognized source of macrophage migration inhibitory factor
    • Calandra, T., J. Bernhagen, R. A. Mitchell, and R. Bucala. 1994. The macrophage is an important and previously unrecognized source of macrophage migration inhibitory factor. J. Exp. Med. 179: 1895-1902.
    • (1994) J. Exp. Med. , vol.179 , pp. 1895-1902
    • Calandra, T.1    Bernhagen, J.2    Mitchell, R.A.3    Bucala, R.4
  • 44
    • 36849069568 scopus 로고    scopus 로고
    • The correlation between proinflammatory cytokines, MAdCAM-1 and cellular infiltration in the inflamed colon from TNF-α gene knockout mice
    • Xu, Y., N. H. Hunt, and S. Bao. 2007. The correlation between proinflammatory cytokines, MAdCAM-1 and cellular infiltration in the inflamed colon from TNF-α gene knockout mice. Immunol. Cell Biol. 85: 633-639.
    • (2007) Immunol. Cell Biol. , vol.85 , pp. 633-639
    • Xu, Y.1    Hunt, N.H.2    Bao, S.3
  • 45
    • 0042834294 scopus 로고    scopus 로고
    • Reactivation of latent tuberculosis infection in TNF-deficient mice
    • Botha, T., and B. Ryffel. 2003. Reactivation of latent tuberculosis infection in TNF-deficient mice. J. Immunol. 171: 3110-3118. (Pubitemid 37093534)
    • (2003) Journal of Immunology , vol.171 , Issue.6 , pp. 3110-3118
    • Botha, T.1    Ryffel, B.2
  • 46
    • 22144465474 scopus 로고    scopus 로고
    • MIP-1α[CCL3] acting on the CCR1 receptor mediates neutrophil migration in immune inflammation via sequential release of TNF-α and LTB4
    • Ramos, C. D., C. Canetti, J. T. Souto, J. S. Silva, C. M. Hogaboam, S. H. Ferreira, and F. Q. Cunha. 2005. MIP-1α[CCL3] acting on the CCR1 receptor mediates neutrophil migration in immune inflammation via sequential release of TNF-α and LTB4. J. Leukoc. Biol. 78: 167-177.
    • (2005) J. Leukoc. Biol. , vol.78 , pp. 167-177
    • Ramos, C.D.1    Canetti, C.2    Souto, J.T.3    Silva, J.S.4    Hogaboam, C.M.5    Ferreira, S.H.6    Cunha, F.Q.7
  • 47
    • 34948909665 scopus 로고    scopus 로고
    • A critical role for CCL2 and CCL3 chemokines in the regulation of polymorphonuclear neutrophils recruitment during corneal infection in mice
    • Xue, M. L., A. Thakur, N. Cole, A. Lloyd, F. Stapleton, D. Wakefield, and M. D. Willcox. 2007. A critical role for CCL2 and CCL3 chemokines in the regulation of polymorphonuclear neutrophils recruitment during corneal infection in mice. Immunol. Cell Biol. 85: 525-531.
    • (2007) Immunol. Cell Biol. , vol.85 , pp. 525-531
    • Xue, M.L.1    Thakur, A.2    Cole, N.3    Lloyd, A.4    Stapleton, F.5    Wakefield, D.6    Willcox, M.D.7
  • 48
    • 0028889387 scopus 로고
    • Inflammatory microcrystals differentially regulate the secretion of macrophage inflammatory protein 1 and interleukin 8 by human neutrophils: A possible mechanism of neutrophil recruitment to sites of inflammation in synovitis
    • Hachicha, M., P. H. Naccache, and S. R. McColl. 1995. Inflammatory microcrystals differentially regulate the secretion of macrophage inflammatory protein 1 and interleukin 8 by human neutrophils: a possible mechanism of neutrophil recruitment to sites of inflammation in synovitis. J. Exp. Med. 182: 2019-2025.
    • (1995) J. Exp. Med. , vol.182 , pp. 2019-2025
    • Hachicha, M.1    Naccache, P.H.2    McColl, S.R.3
  • 49
    • 0034819307 scopus 로고    scopus 로고
    • Macrophage inflammatory protein 1α/CCL3 is required for clearance of an acute Klebsiella pneumoniae pulmonary infection
    • Lindell, D. M., T. J. Standiford, P. Mancuso, Z. J. Leshen, and G. B. Huffnagle. 2001. Macrophage inflammatory protein 1α/CCL3 is required for clearance of an acute Klebsiella pneumoniae pulmonary infection. Infect. Immun. 69: 6364-6369.
    • (2001) Infect. Immun. , vol.69 , pp. 6364-6369
    • Lindell, D.M.1    Standiford, T.J.2    Mancuso, P.3    Leshen, Z.J.4    Huffnagle, G.B.5
  • 50
    • 34948904198 scopus 로고    scopus 로고
    • Selective predisposition to bacterial infections in IRAK-4-deficient children: IRAK-4-dependent TLRs are otherwise redundant in protective immunity
    • Ku, C.-L., H. von Bernuth, C. Picard, S. Y. Zhang, H. H. Chang, K. Yang, M. Chrabieh, A. C. Issekutz, C. K. Cunningham, J. Gallin, et al. 2007. Selective predisposition to bacterial infections in IRAK-4-deficient children: IRAK-4-dependent TLRs are otherwise redundant in protective immunity. J. Exp. Med. 204: 2407-2422.
    • (2007) J. Exp. Med. , vol.204 , pp. 2407-2422
    • Ku, C.-L.1    Von Bernuth, H.2    Picard, C.3    Zhang, S.Y.4    Chang, H.H.5    Yang, K.6    Chrabieh, M.7    Issekutz, A.C.8    Cunningham, C.K.9    Gallin, J.10
  • 52
    • 1942500166 scopus 로고    scopus 로고
    • The presentation and natural history of immunodeficiency caused by nuclear factor κB essential modulator mutation
    • Orange, J. S., A. Jain, Z. K. Ballas, L. C. Schneider, R. S. Geha, and F. A. Bonilla. 2004. The presentation and natural history of immunodeficiency caused by nuclear factor κB essential modulator mutation. J. Allergy Clin. Immunol. 113: 725-733.
    • (2004) J. Allergy Clin. Immunol. , vol.113 , pp. 725-733
    • Orange, J.S.1    Jain, A.2    Ballas, Z.K.3    Schneider, L.C.4    Geha, R.S.5    Bonilla, F.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.