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Volumn 14, Issue 1, 2003, Pages 19-24

Mutagenesis strategies for identifying novel loci associated with disease phenotypes

Author keywords

Ethylnitrosourea (ENU); Mouse mutagenesis; Otitis media with effusion (OME)

Indexed keywords

DNA; ETHYLNITROSOUREA;

EID: 0037329757     PISSN: 10849521     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1084-9521(02)00168-4     Document Type: Review
Times cited : (38)

References (26)
  • 1
    • 0010439688 scopus 로고    scopus 로고
    • Functional annotation of mouse genome sequences
    • Nadeau J.et al. Functional annotation of mouse genome sequences. Science. 291:2001;251-255.
    • (2001) Science , vol.291 , pp. 251-255
    • Nadeau, J.1
  • 2
    • 0033988749 scopus 로고    scopus 로고
    • Establishment of a gene-trap sequence tag library to generate mutant mice from embryonic stem cells
    • Wiles M.V., Vauti F., Otte J., Fuchtbauer E.-M., Ruiz P., Fuchtbauer A.et al. Establishment of a gene-trap sequence tag library to generate mutant mice from embryonic stem cells. Nat. Genet. 24:2000;13-14.
    • (2000) Nat. Genet. , vol.24 , pp. 13-14
    • Wiles, M.V.1    Vauti, F.2    Otte, J.3    Fuchtbauer, E.-M.4    Ruiz, P.5    Fuchtbauer, A.6
  • 3
    • 0034931033 scopus 로고    scopus 로고
    • Functional analysis of secreted and transmembrane proteins critical to mouse development
    • Mitchell K.J., Pinson K.I., Kelly O.G., Brennan J., Zupcich J., Scherz P.et al. Functional analysis of secreted and transmembrane proteins critical to mouse development. Nat. Genet. 28:2001;241-249.
    • (2001) Nat. Genet. , vol.28 , pp. 241-249
    • Mitchell, K.J.1    Pinson, K.I.2    Kelly, O.G.3    Brennan, J.4    Zupcich, J.5    Scherz, P.6
  • 4
    • 0034331003 scopus 로고    scopus 로고
    • Capitalising on large-scale mouse mutagenesis screens
    • Justice M.J. Capitalising on large-scale mouse mutagenesis screens. Nat. Rev. Genet. 1:2000;109-115.
    • (2000) Nat. Rev. Genet. , vol.1 , pp. 109-115
    • Justice, M.J.1
  • 5
    • 0035370789 scopus 로고    scopus 로고
    • Systematic approaches to mouse mutagenesis
    • Brown S.D.M., Balling R. Systematic approaches to mouse mutagenesis. Curr. Opin. Gen. Dev. 11:2001;268-273.
    • (2001) Curr. Opin. Gen. Dev. , vol.11 , pp. 268-273
    • Brown, S.D.M.1    Balling, R.2
  • 6
    • 0031712491 scopus 로고    scopus 로고
    • Mouse mutagenesis - Systematic studies of mammalian gene function
    • Brown S.D.M., Nolan P.M. Mouse mutagenesis - systematic studies of mammalian gene function. Hum. Mol. Genet. 7:1998;1627-1633.
    • (1998) Hum. Mol. Genet. , vol.7 , pp. 1627-1633
    • Brown, S.D.M.1    Nolan, P.M.2
  • 7
    • 0033858522 scopus 로고    scopus 로고
    • The mutagenic action of N-ethyl-N-nitrosourea in the mouse
    • Noveroske J.K., Weber J.S., Justice M.J. The mutagenic action of N-ethyl-N-nitrosourea in the mouse. Mamm. Genome. 11:2000;478-483.
    • (2000) Mamm. Genome , vol.11 , pp. 478-483
    • Noveroske, J.K.1    Weber, J.S.2    Justice, M.J.3
  • 8
    • 0036478946 scopus 로고    scopus 로고
    • Efficient generation and mapping of recessive developmental mutations using ENU mutagenesis
    • Herron B.J., Lu W., Rao C., Liu S., Peters H., Bronson R.T.et al. Efficient generation and mapping of recessive developmental mutations using ENU mutagenesis. Nat. Genet. 30:2002;185-189.
    • (2002) Nat. Genet. , vol.30 , pp. 185-189
    • Herron, B.J.1    Lu, W.2    Rao, C.3    Liu, S.4    Peters, H.5    Bronson, R.T.6
  • 9
    • 0034425410 scopus 로고    scopus 로고
    • A systematic, genome wide, phenotype-driven mutagenesis programme for gene function studies in the mouse
    • Nolan P.M., Peters J., Strivens M., Rogers D.C., Hagan J., Spurr N.et al. A systematic, genome wide, phenotype-driven mutagenesis programme for gene function studies in the mouse. Nat. Genet. 25:2000;440-443.
    • (2000) Nat. Genet. , vol.25 , pp. 440-443
    • Nolan, P.M.1    Peters, J.2    Strivens, M.3    Rogers, D.C.4    Hagan, J.5    Spurr, N.6
  • 11
    • 0342449328 scopus 로고    scopus 로고
    • Ten years of gene targeting: Targeted mouse mutants, from vector design to phenotype analysis
    • Muller U. Ten years of gene targeting: targeted mouse mutants, from vector design to phenotype analysis. Mech. Dev. 82:1999;3-21.
    • (1999) Mech. Dev. , vol.82 , pp. 3-21
    • Muller, U.1
  • 12
    • 0031255352 scopus 로고    scopus 로고
    • Behavioural and functional analysis of mouse phenotype: SHIRPA, a proposed protocol for comprehesive phenotype assessment
    • Rogers D.C., Fisher E.M.C., Brown S.D.M., Peters J., Hunter A.J., Martin J.E. Behavioural and functional analysis of mouse phenotype: SHIRPA, a proposed protocol for comprehesive phenotype assessment. Mamm. Genome. 8:1997;711-713.
    • (1997) Mamm. Genome , vol.8 , pp. 711-713
    • Rogers, D.C.1    Fisher, E.M.C.2    Brown, S.D.M.3    Peters, J.4    Hunter, A.J.5    Martin, J.E.6
  • 13
    • 0033852468 scopus 로고    scopus 로고
    • A mouse phenome project
    • Paigen K., Eppig J.T. A mouse phenome project. Mamm. Genome. 11:2000;715-717.
    • (2000) Mamm. Genome , vol.11 , pp. 715-717
    • Paigen, K.1    Eppig, J.T.2
  • 14
    • 0036075627 scopus 로고    scopus 로고
    • Focusing on the genetics of hearing: You ain't heard nothin' yet
    • Parkinson N., Brown S.D.M. Focusing on the genetics of hearing: you ain't heard nothin' yet. Genome Biol. 3:2002;2006.1-2006.6.
    • (2002) Genome Biol. , vol.3 , pp. 20061-20066
    • Parkinson, N.1    Brown, S.D.M.2
  • 15
    • 0035282744 scopus 로고    scopus 로고
    • The mouse slalom mutant demonstrates a role for Jagged1 in neuroepithelial patterning in the organ of Corti
    • Tsai H.et al. The mouse slalom mutant demonstrates a role for Jagged1 in neuroepithelial patterning in the organ of Corti. Hum. Mol. Genet. 10:2001;507-512.
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 507-512
    • Tsai, H.1
  • 16
    • 0035957432 scopus 로고    scopus 로고
    • The Notch ligand Jagged1 is required for inner ear sensory development
    • Kiernan A.E.et al. The Notch ligand Jagged1 is required for inner ear sensory development. Proc. Natl. Acad. Sci. U.S.A. 98:2001;3873-3878.
    • (2001) Proc. Natl. Acad. Sci. U.S.A. , vol.98 , pp. 3873-3878
    • Kiernan, A.E.1
  • 17
    • 0030914459 scopus 로고    scopus 로고
    • Mutations in the human Jagged1 gene are responsible for Alagille's syndrome
    • Oda T.et al. Mutations in the human Jagged1 gene are responsible for Alagille's syndrome. Nat. Genet. 16:1997;235-242.
    • (1997) Nat. Genet. , vol.16 , pp. 235-242
    • Oda, T.1
  • 18
    • 0025021370 scopus 로고
    • Temporal bone histopathological findings in Alagille's syndrome
    • Okuno T.et al. Temporal bone histopathological findings in Alagille's syndrome. Arch. Otolaryngol. Head Neck Surg. 116:1990;217-220.
    • (1990) Arch. Otolaryngol. Head Neck Surg. , vol.116 , pp. 217-220
    • Okuno, T.1
  • 20
  • 22
    • 0033852333 scopus 로고    scopus 로고
    • Identification of two new Pmp22 mouse mutants using large-scale mutagenesis and a novel rapid mapping strategy
    • Isaacs A.M., Davies K.E., Hunter A.J., Nolan P.M., Vizor L., Peters J.et al. Identification of two new Pmp22 mouse mutants using large-scale mutagenesis and a novel rapid mapping strategy. Hum. Mol. Genet. 9:2000;1865-1871.
    • (2000) Hum. Mol. Genet. , vol.9 , pp. 1865-1871
    • Isaacs, A.M.1    Davies, K.E.2    Hunter, A.J.3    Nolan, P.M.4    Vizor, L.5    Peters, J.6
  • 23
    • 85029463966 scopus 로고    scopus 로고
    • Identification of a new Pmp22 mouse mutant and trafficking analysis of a Pmp22 allelic series suggesting protein aggregates may be protective in Pmp22-associated peripheral neuropathy
    • in press
    • Isaacs AM, Jeans A, Oliver P, Vizor L, Brown SDM, Hunter AJ, et al. Identification of a new Pmp22 mouse mutant and trafficking analysis of a Pmp22 allelic series suggesting protein aggregates may be protective in Pmp22-associated peripheral neuropathy. Mol Cell Neurosci, in press.
    • Mol Cell Neurosci
    • Isaacs, A.M.1    Jeans, A.2    Oliver, P.3    Vizor, L.4    Brown, S.D.M.5    Hunter, A.J.6
  • 26
    • 0034091810 scopus 로고    scopus 로고
    • Genotype-based screen for ENU-induced mutations in mouse embryonic stem cells
    • Chen Y., Yee D., Dains K., Chatterjee A., Cavalcoli J., Schneider E.et al. Genotype-based screen for ENU-induced mutations in mouse embryonic stem cells. Nat. Genet. 24:2000;314-317.
    • (2000) Nat. Genet. , vol.24 , pp. 314-317
    • Chen, Y.1    Yee, D.2    Dains, K.3    Chatterjee, A.4    Cavalcoli, J.5    Schneider, E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.