Characterization of a novel mucopolysaccharidosis type II mouse model and recombinant AAV2/8 vector-mediated gene therapy

Molecules and Cells

Volumn 30, Issue 1, 2010, Pages 13-18

  Jung, Sung Chul ^a   Park, Eun Sook ^a   Choi, Eun Nam ^a   Kim, Chi Hwa ^b   Kim, Su Jin ^c   Jin, Dong Kyu ^c  

^a Ewha Womans University School of Medicine   (South Korea)

^b Samsung Medical Center   (South Korea)

^c Sungkyunkwan University   (South Korea)

Author keywords

adeno associated virus; gene therapy; hunter syndrome; iduronate 2 sulfatase; MPS II mouse model

Indexed keywords

DERMATAN SULFATE; GLYCOSAMINOGLYCAN; HEPARAN SULFATE; IDURONATE 2 SULFATASE; PARVOVIRUS VECTOR;

ADENO ASSOCIATED VIRUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ASSAY; ENZYME DEFICIENCY; GENE THERAPY; HUMAN; HUNTER SYNDROME; KNOCKOUT MOUSE; MOUSE; MUCOPOLYSACCHARIDOSIS; NONHUMAN; QUANTITATIVE ANALYSIS; SERUM; TISSUE DISTRIBUTION; URINARY EXCRETION; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY; VIRUS RECOMBINANT; WESTERN BLOTTING; X CHROMOSOME LINKED DISORDER;

ANIMALS; DEPENDOVIRUS; DISEASE MODELS, ANIMAL; FEMALE; GENE THERAPY; GENETIC VECTORS; HUMANS; IDURONATE SULFATASE; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUCOPOLYSACCHARIDOSIS II; PHENOTYPE;

ADENO-ASSOCIATED VIRUS; MUS;

EID: 77955022207     PISSN: 10168478     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10059-010-0083-2     Document Type: Article

References (32)

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