Mutation in Phex Gene Predisposes BALB/c-PhexHyp-Duk/Y Mice to Otitis Media

PLoS ONE

Volumn 7, Issue 9, 2012, Pages

  Han, Fengchan ^a,b   Yu, Heping ^b   Li, Ping ^a   Zhang, Jiangping ^b   Tian, Cong ^b   Li, Hongbo ^a   Zheng, Qing Yin ^a,b,c  

^a BINZHOU MEDICAL UNIVERSITY   (China)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

^c JACKSON LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AZITHROMYCIN; CYCLINE; FIBROBLAST GROWTH FACTOR 23; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MESSENGER RNA; PHOSPHATE REGULATING NEUTRAL ENDOPEPTIDASE; PROSTAGLANDIN E RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL INFECTION; CCL4 GENE; CELL PROLIFERATION; CILIATED EPITHELIUM; COAGULASE NEGATIVE STAPHYLOCOCCUS; CONTROLLED STUDY; FGF23 GENE; GENE; GENE EXPRESSION; GENE MUTATION; GENETIC MODEL; GENETIC PREDISPOSITION; GENETIC TRANSCRIPTION; GOBLET CELL; IL1B GENE; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE EAR EFFUSION; MIDDLE EAR MUCOSA; MOUSE; NFKB1 GENE; NONHUMAN; OTITIS MEDIA; PENETRANCE; PERINATAL PERIOD; PHEX GENE; PROTEIN EXPRESSION; STAPHYLOCOCCUS AUREUS; TLR2 GENE; TLR4 GENE; TNFALPHA GENE; UPREGULATION;

ANIMALS; CELL PROLIFERATION; CILIA; CYTOKINES; DISEASE MODELS, ANIMAL; EXONS; GENE EXPRESSION REGULATION; GENE ORDER; GENETIC PREDISPOSITION TO DISEASE; GOBLET CELLS; INFLAMMATION; INFLAMMATION MEDIATORS; MICE; MICE, INBRED BALB C; MICE, TRANSGENIC; MUTATION; OTITIS MEDIA; PHEX PHOSPHATE REGULATING NEUTRAL ENDOPEPTIDASE;

BACTERIA (MICROORGANISMS); MUS;

EID: 84866996749     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0043010     Document Type: Article

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