Enhanced susceptibility to acute pneumococcal otitis media in mice deficient in complement C1qa, factor B, and factor B/C2

Infection and Immunity

Volumn 78, Issue 3, 2010, Pages 976-983

  Tong, Hua Hua ^a   Li, Yong Xing ^a   Stahl, Gregory L ^b   Thurman, Joshua M ^c  

^a OHIO STATE UNIVERSITY   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALTERNATIVE COMPLEMENT PATHWAY C3 C5 CONVERTASE; COMPLEMENT; COMPLEMENT COMPONENT C1Q; COMPLEMENT FACTOR B/C2; UNCLASSIFIED DRUG;

ACUTE OTITIS MEDIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COMPLEMENT DEFICIENCY; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; HISTOPATHOLOGY; IMMUNITY; MALE; MOUSE; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; STREPTOCOCCUS PNEUMONIAE;

ANIMALS; BACTEREMIA; BLOOD BACTERICIDAL ACTIVITY; COLONY COUNT, MICROBIAL; COMPLEMENT C1Q; COMPLEMENT C2; COMPLEMENT FACTOR B; DISEASE SUSCEPTIBILITY; EAR, MIDDLE; FEMALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROBIAL VIABILITY; OPSONIN PROTEINS; OTITIS MEDIA; PHAGOCYTOSIS; PNEUMOCOCCAL INFECTIONS; STREPTOCOCCUS PNEUMONIAE;

EID: 77349106655     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.01012-09     Document Type: Article

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