Pathological features in the Lmna Dhe/+ mutant mouse provide a novel model of human otitis media and laminopathies

American Journal of Pathology

Volumn 181, Issue 3, 2012, Pages 761-774

  Zhang, Yan ^a,c   Yu, Heping ^a,b   Xu, Min ^c   Han, Fengchan ^a,d   Tian, Cong ^a,d   Kim, Suejin ^a   Fredman, Elisha ^a   Zhang, Jin ^c   Benedict Alderfer, Cindy ^a   Zheng, Qing Yin ^a,b,c,d  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c MEDICAL SCHOOL OF XI AN JIAOTONG UNIVERSITY   (China)

^d BINZHOU MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PHOSPHORUS; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; AUTACOID; CALCIUM; CYTOKINE; ION; LAMIN A; LMNA PROTEIN, MOUSE;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUDITORY TUBE; CALCIUM BLOOD LEVEL; CELL COUNT; CELL MIGRATION; CLINICAL FEATURE; CONTROLLED STUDY; EAR MALFORMATION; FEMALE; GENE; GENE EXPRESSION; HEARING; HISTOPATHOLOGY; HYPERPHOSPHATEMIA; IMMUNODETECTION; IMMUNOFLUORESCENCE; LAMINOPATHY; LMNA GENE; MACROPHAGE; MALE; MOUSE; MUTATIONAL ANALYSIS; NONHUMAN; OTITIS MEDIA; PERINATAL PERIOD; PERITONEUM MACROPHAGE; PHOSPHATE BLOOD LEVEL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCANNING ELECTRON MICROSCOPY; TYMPANOMETRY; ULTRASTRUCTURE; UPREGULATION; ACOUSTIC IMPEDANCE; ANIMAL; BLOOD; CELL MOTION; CONGENITAL MALFORMATION; DISEASE MODEL; EPITHELIUM CELL; EUKARYOTIC FLAGELLUM; EVOKED BRAIN STEM AUDITORY RESPONSE; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; MIDDLE EAR; MOUSE MUTANT; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SPONTANEOUS OTOACOUSTIC EMISSION; TIME;

ACOUSTIC IMPEDANCE TESTS; ANIMALS; CALCIUM; CELL COUNT; CELL MOVEMENT; CILIA; CYTOKINES; DISEASE MODELS, ANIMAL; EAR, MIDDLE; EPITHELIAL CELLS; EUSTACHIAN TUBE; EVOKED POTENTIALS, AUDITORY, BRAIN STEM; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION MEDIATORS; IONS; LAMIN TYPE A; MACROPHAGES, PERITONEAL; MICE; MICE, MUTANT STRAINS; OTITIS MEDIA; OTOACOUSTIC EMISSIONS, SPONTANEOUS; PHOSPHORUS; TIME FACTORS; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84865204085     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2012.05.031     Document Type: Article

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