메뉴 건너뛰기




Volumn 14, Issue 13, 2000, Pages 1617-1630

Conditional biallelic Nf2 mutation in the mouse promotes manifestations of human neurofibromatosis type 2

Author keywords

Conditional knockout mice; Cre 1oxP; Neurofibromatosis type 2; Schwann cell tumors; Schwannomin; Tumor suppressor gene

Indexed keywords

ANIMAL TISSUE; ARTICLE; GENE MUTATION; GENETIC SUSCEPTIBILITY; KNOCKOUT MOUSE; MOUSE; NEURILEMOMA; NEUROFIBROMATOSIS; NONHUMAN; PRIORITY JOURNAL; SCHWANN CELL;

EID: 0034234894     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (321)

References (41)
  • 3
    • 0016169528 scopus 로고
    • The neurochristopathies. A unifying concept of disease arising in neural crest maldevelopment
    • Bolande, R. 1974. The neurochristopathies. A unifying concept of disease arising in neural crest maldevelopment. Hum. Pathol. 5: 409-420.
    • (1974) Hum. Pathol. , vol.5 , pp. 409-420
    • Bolande, R.1
  • 4
    • 0027415509 scopus 로고
    • The triple origin of skull in higher vertebrates: A study in quailchick chimeras
    • Couly, G.F., Coltey, P.M., and Le Douarin, N.M. 1993. The triple origin of skull in higher vertebrates: A study in quailchick chimeras. Development 117: 409-429.
    • (1993) Development , vol.117 , pp. 409-429
    • Couly, G.F.1    Coltey, P.M.2    Le Douarin, N.M.3
  • 5
    • 0031964774 scopus 로고    scopus 로고
    • Impaired interaction of naturally occurring mutant NF2 protein with actin-based cytoskeleton and membrane
    • Deguen, B., Merel, P., Goutebroze, L., Giovannini, M., Reggio, H., Arpin, M., and Thomas, G. 1998. Impaired interaction of naturally occurring mutant NF2 protein with actin-based cytoskeleton and membrane. Hum. Mol. Genet. 7:217-226.
    • (1998) Hum. Mol. Genet. , vol.7 , pp. 217-226
    • Deguen, B.1    Merel, P.2    Goutebroze, L.3    Giovannini, M.4    Reggio, H.5    Arpin, M.6    Thomas, G.7
  • 6
    • 0019761388 scopus 로고
    • Central neurofibromatosis with bilateral acoustic neuroma
    • Eldridge, R. 1981. Central neurofibromatosis with bilateral acoustic neuroma. Adv. Neurol. 29: 57-65.
    • (1981) Adv. Neurol. , vol.29 , pp. 57-65
    • Eldridge, R.1
  • 7
    • 0020082369 scopus 로고
    • Peripheral nerve sheath tumors: An electron microscopic study of 43 cases
    • Erlandson, R.A. and Woodruff, J.M. 1982. Peripheral nerve sheath tumors: An electron microscopic study of 43 cases. Cancer 49: 273-287.
    • (1982) Cancer , vol.49 , pp. 273-287
    • Erlandson, R.A.1    Woodruff, J.M.2
  • 10
    • 0027280936 scopus 로고
    • Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting
    • Gu, H., Zou, Y.R., and Rajewsky, K. 1993. Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting. Cell 73: 1155-1164.
    • (1993) Cell , vol.73 , pp. 1155-1164
    • Gu, H.1    Zou, Y.R.2    Rajewsky, K.3
  • 11
    • 0028059099 scopus 로고
    • Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting
    • Gu, H., Marth, J.D., Orban, P.C., Mossmann, H., and Rajewsky, K. 1994. Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting. Science 265:103-106.
    • (1994) Science , vol.265 , pp. 103-106
    • Gu, H.1    Marth, J.D.2    Orban, P.C.3    Mossmann, H.4    Rajewsky, K.5
  • 12
    • 0032899713 scopus 로고    scopus 로고
    • Increased expression of the NF2 tumor suppressor gene product, merlin, impairs cell motility, adhesion and spreading
    • Gutmann, D.H., Sherman, L., Seftor, L., Haipek, C., Hoang Lu, K., and Hendrix, M. 1999. Increased expression of the NF2 tumor suppressor gene product, merlin, impairs cell motility, adhesion and spreading. Hum. Mol. Genet. 8: 267-275.
    • (1999) Hum. Mol. Genet. , vol.8 , pp. 267-275
    • Gutmann, D.H.1    Sherman, L.2    Seftor, L.3    Haipek, C.4    Hoang Lu, K.5    Hendrix, M.6
  • 13
    • 0030444452 scopus 로고    scopus 로고
    • Tumor suppressor gene mutations in mice
    • Jacks, T. 1996. Tumor suppressor gene mutations in mice. Annu. Rev. Genet. 30: 603-636.
    • (1996) Annu. Rev. Genet. , vol.30 , pp. 603-636
    • Jacks, T.1
  • 16
    • 0032551944 scopus 로고    scopus 로고
    • Impairment of cell adhesion by expression of the mutant neurofibromatosis type 2 (NF2) genes which lack exons in the ERM-homology domain
    • Koga, H., Araki, N., Takeshima, H., Nishi, T., Hirota, T., Kimura, Y., Nakao, M., and Saya, H. 1998. Impairment of cell adhesion by expression of the mutant neurofibromatosis type 2 (NF2) genes which lack exons in the ERM-homology domain. Oncogene 17: 801-810.
    • (1998) Oncogene , vol.17 , pp. 801-810
    • Koga, H.1    Araki, N.2    Takeshima, H.3    Nishi, T.4    Hirota, T.5    Kimura, Y.6    Nakao, M.7    Saya, H.8
  • 17
    • 0030642178 scopus 로고    scopus 로고
    • P0 is constitutively expressed in the rat neural crest and embryonic nerves and is negatively and positively regulated by axons to generate non-myelin-forming and myelin-forming Schwann cells, respectively
    • Lee, M., Brennan, A., Blanchard, A., Zoidl, G., Dong, Z., Tabernero, A., Zoidl, C., Dent, M.A., Jessen, K.R., and Mirsky, R. 1997. P0 is constitutively expressed in the rat neural crest and embryonic nerves and is negatively and positively regulated by axons to generate non-myelin-forming and myelin-forming Schwann cells, respectively. Mol. Cell. Neurosci. 8: 336-350.
    • (1997) Mol. Cell. Neurosci. , vol.8 , pp. 336-350
    • Lee, M.1    Brennan, A.2    Blanchard, A.3    Zoidl, G.4    Dong, Z.5    Tabernero, A.6    Zoidl, C.7    Dent, M.A.8    Jessen, K.R.9    Mirsky, R.10
  • 18
    • 0023687127 scopus 로고
    • Spatial organization of the epithelium and the role of neural crest cells in the initiation of the mammalian tooth germ
    • Lumsden, A.G. 1988. Spatial organization of the epithelium and the role of neural crest cells in the initiation of the mammalian tooth germ. Development 103: 155-169.
    • (1988) Development , vol.103 , pp. 155-169
    • Lumsden, A.G.1
  • 19
    • 0006981826 scopus 로고    scopus 로고
    • Neurofibromatosis type 2
    • ed. B. Vogelstein and K.W. Kinzler, McGraw-Hill, USA
    • MacCollin, M. and Gusella, J. 1998. Neurofibromatosis type 2. In The genetic basis of human cancer (ed. B. Vogelstein and K.W. Kinzler), pp. 443-453. McGraw-Hill, USA.
    • (1998) The Genetic Basis of Human Cancer , pp. 443-453
    • MacCollin, M.1    Gusella, J.2
  • 20
    • 0025218396 scopus 로고
    • Intracranial calcified deposits in neurofibromatosis type 2. A CT study of 11 cases
    • Mayfrank, L., Mohadjer, M., and Wullich, B. 1990. Intracranial calcified deposits in neurofibromatosis type 2. A CT study of 11 cases. Neuroradiology 32:33-37.
    • (1990) Neuroradiology , vol.32 , pp. 33-37
    • Mayfrank, L.1    Mohadjer, M.2    Wullich, B.3
  • 21
    • 0030924657 scopus 로고    scopus 로고
    • The NF2 tumor suppressor gene product is essential for extraembryonic development immediately prior to gastrulation
    • McClatchey, A.I., Saotome, I., Ramesh, V., Gusella, J.F., and Jacks, T. 1997. The NF2 tumor suppressor gene product is essential for extraembryonic development immediately prior to gastrulation. Genes & Dev, 11: 1253-1265.
    • (1997) Genes & Dev , vol.11 , pp. 1253-1265
    • McClatchey, A.I.1    Saotome, I.2    Ramesh, V.3    Gusella, J.F.4    Jacks, T.5
  • 22
    • 0032522603 scopus 로고    scopus 로고
    • Mice heterozygous for a mutation at the NF2 tumor suppressor locus develop a range of highly metastatic tumors
    • McClatchey, A.I., Saotome, I., Mercer, K., Crowley, D., Gusella, J.F., Bronson, R.T., and Jacks, T. 1998. Mice heterozygous for a mutation at the NF2 tumor suppressor locus develop a range of highly metastatic tumors. Genes & Dev. 12: 1121-1133.
    • (1998) Genes & Dev. , vol.12 , pp. 1121-1133
    • McClatchey, A.I.1    Saotome, I.2    Mercer, K.3    Crowley, D.4    Gusella, J.F.5    Bronson, R.T.6    Jacks, T.7
  • 23
    • 0026612662 scopus 로고
    • P0 promoter directs expression of reporter and toxin genes to Schwann cells of transgenic mice
    • Messing, A., Behringer, R.R., Hammang, J.P., Palmiter, R.D., Brinster, R.L., and Lemke, G. 1992. P0 promoter directs expression of reporter and toxin genes to Schwann cells of transgenic mice. Neuron 8: 507-520.
    • (1992) Neuron , vol.8 , pp. 507-520
    • Messing, A.1    Behringer, R.R.2    Hammang, J.P.3    Palmiter, R.D.4    Brinster, R.L.5    Lemke, G.6
  • 26
    • 0031443874 scopus 로고    scopus 로고
    • Protamine-Cre recombinase transgenes efficiently recombine target sequences in the male germ line of mice, but not in embryonic stem cells
    • O'Gorman, S., Dagenais, N.A., Qian, M., and Marchuk, Y. 1997. Protamine-Cre recombinase transgenes efficiently recombine target sequences in the male germ line of mice, but not in embryonic stem cells. Proc. Natl. Acad. Sci. 94: 14602-14607.
    • (1997) Proc. Natl. Acad. Sci. , vol.94 , pp. 14602-14607
    • O'Gorman, S.1    Dagenais, N.A.2    Qian, M.3    Marchuk, Y.4
  • 27
    • 0033960925 scopus 로고    scopus 로고
    • Formation of corneal endothelium is essential for anterior segment development: A transgenic mouse model of anterior segment dysgenesis
    • Reneker, L.W., Silversides, D.W., Xu, L., and Overbeek, P.A. 2000. Formation of corneal endothelium is essential for anterior segment development: A transgenic mouse model of anterior segment dysgenesis. Development 127: 533-542.
    • (2000) Development , vol.127 , pp. 533-542
    • Reneker, L.W.1    Silversides, D.W.2    Xu, L.3    Overbeek, P.A.4
  • 30
    • 0026802046 scopus 로고
    • A gene family consisting of ezrin, radixin and moesin. Its specific localization at actin filament/plasma membrane association sites
    • Sato, N., Funayama, N., Nagafuchi, A., Yonemura, S., Tsukita, S., and Tsukita, S. 1992. A gene family consisting of ezrin, radixin and moesin. Its specific localization at actin filament/plasma membrane association sites. J. Cell Sci. 103: 131-143.
    • (1992) J. Cell Sci. , vol.103 , pp. 131-143
    • Sato, N.1    Funayama, N.2    Nagafuchi, A.3    Yonemura, S.4    Tsukita, S.5
  • 31
    • 0028907620 scopus 로고
    • Neurofibromatosis type 2 (NF2) gene is somatically mutated in mesothelioma but not in lung cancer
    • Sekido, Y., Pass, H.I., Bader, S., Mew, D.J.Y., Christman, M.F., Gazdar, A.F., and Minna, J.D. 1995. Neurofibromatosis type 2 (NF2) gene is somatically mutated in mesothelioma but not in lung cancer. Cancer Res. 55: 1227-1231.
    • (1995) Cancer Res. , vol.55 , pp. 1227-1231
    • Sekido, Y.1    Pass, H.I.2    Bader, S.3    Mew, D.J.Y.4    Christman, M.F.5    Gazdar, A.F.6    Minna, J.D.7
  • 33
    • 0019888362 scopus 로고
    • Bacteriophage P1 site-specific recombination. I. Recombination between loxP sites
    • Sternberg, N. and Hamilton, D. 1981. Bacteriophage P1 site-specific recombination. I. Recombination between loxP sites. J. Mol. Biol. 150: 467-486.
    • (1981) J. Mol. Biol. , vol.150 , pp. 467-486
    • Sternberg, N.1    Hamilton, D.2
  • 34
    • 0028245681 scopus 로고
    • Detection of cellular proteins that interact with the NF2 tumor suppressor gene product
    • Takeshima, H., Izawa, I., Lee, P.S.Y., Safdar, N., Levin, V.A., and Saya, H. 1994. Detection of cellular proteins that interact with the NF2 tumor suppressor gene product. Oncogene 9: 2135-2144.
    • (1994) Oncogene , vol.9 , pp. 2135-2144
    • Takeshima, H.1    Izawa, I.2    Lee, P.S.Y.3    Safdar, N.4    Levin, V.A.5    Saya, H.6
  • 35
    • 0026771287 scopus 로고
    • Highly efficient gene targeting in embryonic stem cells through homologous recombination with isogenic DNA constructs
    • te Riele, H., Maandag, E.R., and Berns, A. 1992. Highly efficient gene targeting in embryonic stem cells through homologous recombination with isogenic DNA constructs. Proc. Natl. Acad. Sci. 89: 5128-5132.
    • (1992) Proc. Natl. Acad. Sci. , vol.89 , pp. 5128-5132
    • Te Riele, H.1    Maandag, E.R.2    Berns, A.3
  • 38
    • 0000686878 scopus 로고
    • Pathology of neurofibromatosis 1 and 2
    • ed. S.M. Huson and R.A.C. Hughes, Chapman & Hall, London, UK
    • Wiestler, O.D. and Radner, H. 1994. Pathology of neurofibromatosis 1 and 2. In The neurofibromatoses. A clinical and pathogenetic overview (ed. S.M. Huson and R.A.C. Hughes), pp. 135-159. Chapman & Hall, London, UK.
    • (1994) The Neurofibromatoses. A Clinical and Pathogenetic Overview , pp. 135-159
    • Wiestler, O.D.1    Radner, H.2
  • 39
    • 0342580257 scopus 로고
    • The embryonic tumours and teratomas
    • Butterworth and Co., London, UK
    • Willis, R.A. 1958. The embryonic tumours and teratomas. In The borderland of embryology and pathology, pp. 410-454. Butterworth and Co., London, UK.
    • (1958) The Borderland of Embryology and Pathology , pp. 410-454
    • Willis, R.A.1
  • 40
    • 0033179120 scopus 로고    scopus 로고
    • A novel transgenic technique that allows specific marking of the neural crest cell lineage in mice
    • Yamauchi, Y., Abe, K., Mantani, A., Hitoshi, Y., Suzuki, M., Osuzu, F., Kuratani, S., and Yamamura, K. 1999. A novel transgenic technique that allows specific marking of the neural crest cell lineage in mice. Dev. Biol. 212: 191-203.
    • (1999) Dev. Biol. , vol.212 , pp. 191-203
    • Yamauchi, Y.1    Abe, K.2    Mantani, A.3    Hitoshi, Y.4    Suzuki, M.5    Osuzu, F.6    Kuratani, S.7    Yamamura, K.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.