In pursuit of small molecule chemistry for calcium-permeable non-selective TRPC channels - Mirage or pot of gold?

British Journal of Pharmacology

Volumn 170, Issue 3, 2013, Pages 459-474

  Bon, Robin S ^a   Beech, David J ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

calcium channel; calcium signalling; cationic channel; ion channel inhibitors; sodium channel

Indexed keywords

2 AMINOETHOXYDIPHENYLBORANE; 2 AMINOQUINOLINE; 2 AMINOTHIAZOLE DERIVATIVE; CALCIUM; CORTICOSTEROID DERIVATIVE; DAIDZEIN; EFENAMIC ACID; FATTY ACID DERIVATIVE; GENISTEIN; HYPERFORIN; IMIDAZOLE DERIVATIVE; MATRIX METALLOPROTEINASE; PHLOROGLUCINOL DERIVATIVE; PIOGLITAZONE; PIPERAZINE DERIVATIVE; PIPERIDINE DERIVATIVE; POLYPHENOL DERIVATIVE; PYRAZOLE DERIVATIVE; ROSIGLITAZONE; SULFONAMIDE; THIOUREA DERIVATIVE; TRANSIENT RECEPTOR POTENTIAL CHANNEL 1; TRANSIENT RECEPTOR POTENTIAL CHANNEL 3; TRANSIENT RECEPTOR POTENTIAL CHANNEL 4; TRANSIENT RECEPTOR POTENTIAL CHANNEL 5; TRANSIENT RECEPTOR POTENTIAL CHANNEL 6; TRANSIENT RECEPTOR POTENTIAL CHANNEL 7; TRANSIENT RECEPTOR POTENTIAL CHANNEL C; TROGLITAZONE; UNINDEXED DRUG;

ANTIOXIDANT ACTIVITY; BIOCHEMISTRY; CALCIUM TRANSPORT; CELL ADHESION; CELL MIGRATION; CELL PROLIFERATION; CELL SURVIVAL; DRUG BINDING SITE; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG STRUCTURE; HEART INFARCTION; HUMAN; MAMMAL CELL; MOLECULAR BIOLOGY; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; REVIEW; SODIUM TRANSPORT; STRUCTURE ANALYSIS;

CALCIUM CHANNEL; CALCIUM SIGNALLING; CATIONIC CHANNEL; ION CHANNEL INHIBITORS; SODIUM CHANNEL;

ANIMALS; CALCIUM; DRUG DISCOVERY; HUMANS; ION TRANSPORT; MEMBRANE POTENTIALS; MEMBRANE TRANSPORT MODULATORS; MOLECULAR STRUCTURE; PERMEABILITY; SODIUM; STRUCTURE-ACTIVITY RELATIONSHIP; TRPC CATION CHANNELS;

EID: 84884552153     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.12274     Document Type: Review

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