Requirement of TRPC channels in netrin-1-induced chemotropic turning of nerve growth cones

Nature

Volumn 434, Issue 7035, 2005, Pages 898-904

  Wang, Gordon X ^a   Poo, Mu Ming ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSENSORS; BRAIN; CELLS; CONES; GROWTH KINETICS; MEMBRANES; NUCLEIC ACIDS; PHARMACODYNAMICS; PROTEINS;

OLIGONUCLEOTIDES; OSMOLARITY; TEMPERATURE SENSORS; TRANSIENT RECEPTOR POTENTIAL (TRP);

NEUROLOGY;

BRAIN DERIVED NEUROTROPHIC FACTOR; CALCIUM ION; ION CHANNEL; MEMBRANE PROTEIN; MORPHOLINE; NETRIN; NETRIN 1; OLIGONUCLEOTIDE; PROTEIN TRPC1; TRANSIENT RECEPTOR POTENTIAL CHANNEL; UNCLASSIFIED DRUG; 1 (2 (3 (4 METHOXYPHENYL)PROPOXY) 4 METHOXYPHENYLETHYL) 1H IMIDAZOLE; 1-(2-(3-(4-METHOXYPHENYL)PROPOXY)-4-METHOXYPHENYLETHYL)-1H-IMIDAZOLE; CALCIUM; CALCIUM CHANNEL; CALCIUM CHANNEL BLOCKING AGENT; IMIDAZOLE DERIVATIVE; NERVE GROWTH FACTOR; NETRIN-1; TRANSIENT RECEPTOR POTENTIAL CHANNEL C; TRANSIENT RECEPTOR POTENTIAL CHANNEL RELATED PROTEIN 1; TRANSIENT RECEPTOR POTENTIAL CHANNEL-RELATED PROTEIN 1; TUMOR SUPPRESSOR PROTEIN;

NEUROLOGY;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL MEMBRANE DEPOLARIZATION; CONTROLLED STUDY; CULTURE MEDIUM; DOWN REGULATION; ELECTRIC POTENTIAL; GROWTH CONE; MECHANICAL STRESS; NERVE CELL CULTURE; NERVE FIBER; NERVE FIBER GROWTH; NONHUMAN; OSMOLARITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; ROTATION; SIGNAL DETECTION; TASTE; THERMORECEPTOR; WHOLE CELL; XENOPUS; ANIMAL; CALCIUM SIGNALING; CELL CULTURE; CELL MEMBRANE POTENTIAL; CELL MOTION; CELL SHAPE; DRUG EFFECT; ELECTRIC CONDUCTIVITY; GENETICS; METABOLISM; PRENATAL DEVELOPMENT; XENOPUS LAEVIS;

ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CALCIUM; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS; CALCIUM SIGNALING; CELL MOVEMENT; CELL SHAPE; CELLS, CULTURED; ELECTRIC CONDUCTIVITY; GROWTH CONES; IMIDAZOLES; MEMBRANE POTENTIALS; NERVE GROWTH FACTORS; TRPC CATION CHANNELS; TUMOR SUPPRESSOR PROTEINS; XENOPUS LAEVIS;

EID: 17244383526     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature03478     Document Type: Article

References (30)

1. Clapham, D. E. TRP channels as cellular sensors. Nature 426, 517-524 (2003).
2. Montell, C, Birnbaumer, L. & Flockerzi, V. The TRP channels, a remarkably functional family. Cell 108, 595-598 (2002).
3. Hong, K., Nishiyama, M., Henley, J., Tessier-Lavigne, M. & Poo, M. Calcium signalling in the guidance of nerve growth by netrin-1. Nature 403, 93-98 (2000).
4. Henley, J. & Poo, M. M. Calcium mediates bidirectional growth cone turning induced by myelin-associated glycoprotein. Neuron 44, 909-916 (2004).
5. 2- signals. Trends Cell Biol. 14, 320-330 (2004).
6. 2+ channels sets the polarity of nerve growth-cone turning. Nature 423, 990-995 (2003).
7. Ming, G. L. et al. cAMP-dependent growth cone guidance by netrin-1. Neuron 19, 1225-1235 (1997).
8. Kim, S. J. et al. Activation of the TRPC1 cation channel by metabotropic glutamate receptor mGluR1. Nature 426, 285-291 (2003).
9. Li, H. S., Xu, X. Z. & Montell, C. Activation of a TRPC3-dependent cation current through the neurotrophin BDNF. Neuron 24, 261-273(1999).
10. 2+ entry. J. Biol. Chem. 273, 133-142(1998).
11. Schwarz, G., Droogmans, G. & Nilkis, B. Multiple effects of SKF 96365 on ionic currents and intracellular calcium in human endothelial cells. Cell Calcium 15, 45-54(1994).
12. Greka, A., Navarro, B., Oancea, E., Duggan, A, & Clapham, D. E. TRPC5 is a regulator of hippocampal neunte length and growth cone morphology. Nature Neurosci. 6, 837-845 (2003).
13. Song, H. J., Ming, G. L. & Poo, M. M. cAMP-induced switching in turning direction of nerve growth cones. Nature 388, 275-279 (1997).
14. Jung, S. et al. Lanthanides potentiate TRPC5 currents by an action at extracellular sites close to the pore mouth. J. Biol. Chem. 278, 3562-3571 (2003).
15. Inoue, R. et al. The transient receptor potential protein homologue TRP6 is the essential component of vascular alpha(1)-adrenoceptor-activated Ca(2+)-permeable cation channel. Circ. Res. 88, 325-332(2001).
16. Gomez, T. M., Robles, E., Poo, M. & Spitzer, N. C. Filopodial calcium transients promote substrate-dependent growth cone turning. Science 291, 1983-1987 (2001).
17. Li, Y. et al. Essential role of TRPC channels in the guidance of nerve growth cones by brain-derived neurotrophic factor. Nature doi:10.1038/ nature03477 (this issue).
18. Bobanovic, L. K. et al. Molecular cloning and immunolocalization of a novel vertebrate trp homologue from Xenopus. Biochem. J. 340, 593-599 (1999).
19. 2+ inflow in Xenopus laevis oocytes. Mol. Cell. Biochem. 214, 63-74 (2000).
20. 2+sensitive cation channels. J. Biol. Chem. 275, 27799-27805 (2000).
21. Strubing, C., Krapivinsky, G., Krapivinsky, L. & Clapham, D. E. TRPC1 and TRPC5 form a novel cation channel in mammalian brain. Neuron 29, 645-655 (2001).
22. Strubing, C., Krapivinsky, G., Krapivinsky, L. & Clapham, D. E. Formation of novel TRPC channels by complex subunit interactions in embryonic brain. J. Biol. Chem. 278, 39014-39019 (2003).
23. Xu, X. Z., Li, H. S., Guggino, W. B. & Montell, C. Coassembly of TRP and TRPL produces a distinct store-operated conductance. Cell 89, 1155-1164 (1997).
24. Amiri, H., Schultz, G. & Schaefer, M. FRET-based analysis of TRPC subunit stoichiometry. Cell Calcium 33, 463-470 (2003).
25. Schaefer, M., Plant, T. D., Stresow, N., Albrecht, N. & Schultz, G. Functional differences between TRPC4 splice variants. J. Biol. Chem. 277, 3752-3759 (2002).
26. Goel, M., Sinkins, W. G. & Schilling, W. P. Selective association of TRPC channel subunits in rat brain synaptosomes. J. Biol. Chem. 277, 48303-48310 (2002).
27. Hofmann, T., Schaefer, M., Schultz, G. & Gudermann, T. Subunit composition of mammalian transient receptor potential channels in living cells. Proc. Natl Acad. Sci. USA 99, 7461-7466 (2002).
28. Lohof, A. M. et al. Asymmetric modulation of cytosolic cAMP activity induces growth cone turning. J. Neurosci. 12, 1253-1261 (1992).
29. 2+ in developing Xenopus neurons. J. Neurosci. 13, 4936-4948 (1993).
30. 2+ channels with a high affinity for L-type channels in cerebellar granule neurons. Proc. Natl Acad. Sci. USA 91, 878-882 (1994).