Stereo-selective inhibition of transient receptor potential TRPC5 cation channels by neuroactive steroids

British Journal of Pharmacology

Volumn 162, Issue 7, 2011, Pages 1509-1520

  Majeed, Y ^a   Amer, M S ^a,b   Agarwal, A K ^a   McKeown, L ^a   Porter, K E ^a   O'Regan, D J ^c   Naylor, J ^a   Fishwick, C W G ^a   Muraki, K ^a,d   Beech, D J ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b MENOUFIA UNIVERSITY   (Egypt)

^c LEEDS GENERAL INFIRMARY   (United Kingdom)

^d AICHI GAKUIN UNIVERSITY   (Japan)

Author keywords

cationic channel; neurosteroid; progesterone; transient receptor potential canonical 5

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; ESTRADIOL; PRASTERONE SULFATE; PREGNENOLONE; PROGESTERONE; STEROID; TRANSIENT RECEPTOR POTENTIAL CHANNEL 5;

ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SMOOTH MUSCLE FIBER; STRUCTURE ACTIVITY RELATION; VASCULAR SMOOTH MUSCLE; VOLTAGE CLAMP;

CALCIUM; CELLS, CULTURED; DIHYDROTESTOSTERONE; ESTRADIOL; GONADAL STEROID HORMONES; HEK293 CELLS; HUMANS; LYSOPHOSPHOLIPIDS; MYOCYTES, SMOOTH MUSCLE; PATCH-CLAMP TECHNIQUES; PHOSPHOLIPIDS; PREGNENOLONE; PROGESTERONE; SPHINGOSINE; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TRPC CATION CHANNELS;

EID: 79952386129     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2010.01136.x     Document Type: Article

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