TRPC3 and TRPC6 are essential for normal mechanotransduction in subsets of sensory neurons and cochlear hair cells

Open Biology

Volumn 2, Issue MAY, 2012, Pages

  Quick, Kathryn ^a   Zhao, Jing ^a   Eijkelkamp, Niels ^a   Linley, John E ^a   Rugiero, Francois ^a   Cox, James J ^a   Raouf, Ramin ^a   Gringhuis, Martine ^a   Sexton, Jane E ^a   Abramowitz, Joel ^b   Taylor, Ruth ^c   Forge, Andy ^c   Ashmore, Jonathan ^c   Kirkwood, Nerissa ^d   Kros, Corné J ^d   Richardson, Guy P ^d   Freichel, Marc ^e   Flockerzi, Veit ^e   Birnbaumer, Lutz ^b   Wood, John N ^a,f  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d UNIVERSITY OF SUSSEX   (United Kingdom)

^e SAARLAND UNIVERSITY   (Germany)

^f Seoul National University   (South Korea)

Author keywords

Hearing; Mechanosensation; Touch

Indexed keywords

MUS;

1 (2 (3 (4 METHOXYPHENYL)PROPOXY) 4 METHOXYPHENYLETHYL) 1H IMIDAZOLE; 1-(2-(3-(4-METHOXYPHENYL)PROPOXY)-4-METHOXYPHENYLETHYL)-1H-IMIDAZOLE; IMIDAZOLE DERIVATIVE; NERVE PROTEIN; TRANSIENT RECEPTOR POTENTIAL CHANNEL 3; TRANSIENT RECEPTOR POTENTIAL CHANNEL C; TRPC6 PROTEIN, MOUSE;

ACTION POTENTIAL; ANIMAL; ARTICLE; BIOSYNTHESIS; C57BL MOUSE; CELL CULTURE; CELL SIZE; CLASSIFICATION; CYTOLOGY; DRUG EFFECT; EVOKED BRAIN STEM AUDITORY RESPONSE; GENETICS; HAIR CELL; HEARING; HYPESTHESIA; ION TRANSPORT; MECHANOSENSATION; MECHANOTRANSDUCTION; MOUSE; MOUSE MUTANT; PATHOPHYSIOLOGY; PERCEPTION DEAFNESS; PHYSIOLOGY; PRIMARY CELL CULTURE; SENSORY RECEPTOR; SPINAL GANGLION; TOUCH; ULTRASTRUCTURE; VESTIBULAR DISORDER;

HEARING; MECHANOSENSATION; TOUCH;

ACTION POTENTIALS; ANIMALS; CELL SIZE; CELLS, CULTURED; EVOKED POTENTIALS, AUDITORY, BRAIN STEM; GANGLIA, SPINAL; HAIR CELLS, AUDITORY; HAIR CELLS, AUDITORY, OUTER; HEARING LOSS, SENSORINEURAL; HYPESTHESIA; IMIDAZOLES; ION TRANSPORT; MECHANOTRANSDUCTION, CELLULAR; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NERVE TISSUE PROTEINS; PRIMARY CELL CULTURE; SENSORY RECEPTOR CELLS; TRPC CATION CHANNELS; VESTIBULAR DISEASES;

EID: 84864204713     PISSN: None     EISSN: 20462441     Source Type: Journal    
DOI: 10.1098/rsob.120068     Document Type: Article

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