Constitutively active TRPC channels of adipocytes confer a mechanism for sensing dietary fatty acids and regulating adiponectin

Circulation Research

Volumn 111, Issue 2, 2012, Pages 191-200

  Sukumar, Piruthivi ^a   Sedo, Alicia ^a   Li, Jing ^a   Wilson, Lesley A ^a   O'Regan, David ^a,b   Lippiat, Jonathan D ^a   Porter, Karen E ^a   Kearney, Mark T ^a   Ainscough, Justin F X ^a   Beech, David J ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b LEEDS GENERAL INFIRMARY   (United Kingdom)

Author keywords

linolenic acid; adipocyte; adiponectin; calcium channel; transient receptor potential

Indexed keywords

ADIPONECTIN; CALCIUM; CALCIUM CHANNEL; FATTY ACID; LANTHANUM; LINOLENIC ACID; OMEGA 3 FATTY ACID; ROSIGLITAZONE; TRANSIENT RECEPTOR POTENTIAL CHANNEL 1; TRANSIENT RECEPTOR POTENTIAL CHANNEL 5;

ADIPOCYTE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ATHEROSCLEROSIS; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL DIFFERENTIATION; CELL MATURATION; CELL STRAIN HEK293; CONTROLLED STUDY; CYTOKINE PRODUCTION; ELECTROPHYSIOLOGY; FAT INTAKE; HEART PROTECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PATCH CLAMP; POTASSIUM TRANSPORT; PRIORITY JOURNAL; PROADIPOCYTE; TRANSGENIC MOUSE;

3T3 CELLS; ADIPOCYTES; ADIPONECTIN; ANIMALS; DOWN-REGULATION; FATTY ACIDS, OMEGA-3; HEK293 CELLS; HUMANS; INFLAMMATION MEDIATORS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; ORGAN CULTURE TECHNIQUES; PROTEIN MULTIMERIZATION; TRPC CATION CHANNELS;

EID: 84863724901     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.112.270751     Document Type: Article

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