Neuronal store-operated calcium entry pathway as a novel therapeutic target for Huntington's disease treatment

Chemistry and Biology

Volumn 18, Issue 6, 2011, Pages 777-793

  Wu, Jun ^a   Shih, Hsin Pei ^b,d   Vigont, Vladimir ^c   Hrdlicka, Lori ^b   Diggins, Len ^b   Singh, Carol ^b   Mahoney, Matt ^b   Chesworth, Richard ^b   Shapiro, Gideon ^b   Zimina, Olga ^c   Chen, Xuesong ^a   Wu, Qingqing ^a   Glushankova, Lyubov ^c   Ahlijanian, Michael ^b,e   Koenig, Gerhard ^b   Mozhayeva, Galina N ^c   Kaznacheyeva, Elena ^c   Bezprozvanny, Ilya ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b EnVivo Pharmaceuticals   (United States)

^c INSTITUTE OF CYTOLOGY   (Russian Federation)

^d VERTEX PHARMACEUTICALS   (United States)

^e BRISTOL MYERS SQUIBB   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; DIPHENYL ETHER DERIVATIVE; EVP 4593; FURA 2; GLUTAMIC ACID; HUNTINGTON PROTEIN, MOUSE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NERVE PROTEIN; NUCLEAR PROTEIN; QUINAZOLINE DERIVATIVE; SMALL INTERFERING RNA; TRANSIENT RECEPTOR POTENTIAL CHANNEL C; TRANSIENT RECEPTOR POTENTIAL CHANNEL RELATED PROTEIN 1; TRANSIENT RECEPTOR POTENTIAL CHANNEL-RELATED PROTEIN 1;

ANIMAL; APOPTOSIS; ARTICLE; CELL CULTURE; CHEMISTRY; DISEASE MODEL; DROSOPHILA; DRUG ANTAGONISM; GENETICS; HUNTINGTON CHOREA; METABOLISM; MOUSE; NERVE CELL; PHYSIOLOGY; RNA INTERFERENCE; TRANSGENIC MOUSE;

ANIMALS; APOPTOSIS; CALCIUM; CELLS, CULTURED; DISEASE MODELS, ANIMAL; DROSOPHILA; FURA-2; GLUTAMIC ACID; HUNTINGTON DISEASE; MICE; MICE, TRANSGENIC; NERVE TISSUE PROTEINS; NEURONS; NF-KAPPA B; NUCLEAR PROTEINS; PHENYL ETHERS; QUINAZOLINES; RNA INTERFERENCE; RNA, SMALL INTERFERING; TRPC CATION CHANNELS;

EID: 79959495111     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2011.04.012     Document Type: Article

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