3,5-Bis(trifluoromethyl)pyrazoles: A novel class of NFAT transcription factor regulator

Journal of Medicinal Chemistry

Volumn 43, Issue 16, 2000, Pages 2975-2981

  Djuric, S W ^a   Wiedeman, P E ^a   Zhou, X ^a   Ballaron, S ^a   Bauch, J ^a   Chen, Y W ^a   Chiou, X G ^a   Fey, T ^a   Gauvin, D ^a   Gubbins, E ^a   Hsieh, G C ^a   Bamaung, N Y ^a   Marsh, K C ^a   Mollison, K W ^a   Pong, M ^a   Shaughnessy, T K ^a   Sheets, M P ^a   Smith, M ^a   Trevillyan, J M ^a   Warrior, U ^a   Wegner, C D ^a   Carter, G W ^a   Basha, A ^a   Liu, H ^a   Luly, J R ^a   Madar, D J ^a   Sciotti, R J ^a   Tu, N P ^a   Wagenaar, F L ^a   more..

^a ABBOTT LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3,5 BIS(TRIFLUOROMETHYL)PYRAZOLE; CALCINEURIN; CYCLOSPORIN A; CYTOKINE; EOTAXIN; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 8; PREDNISOLONE; PYRAZOLE DERIVATIVE; TACROLIMUS; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ASTHMA; CONTROLLED STUDY; DRUG MECHANISM; GENE EXPRESSION REGULATION; GRAFT REJECTION; HUMAN; HUMAN CELL; IMMUNOSUPPRESSIVE TREATMENT; MONKEY; NONHUMAN; RAT; SIGNAL TRANSDUCTION; T LYMPHOCYTE; TRANSCRIPTION REGULATION;

ANIMALS; ASTHMA; CELL DIVISION; CHEMOKINES, CC; COMBINATORIAL CHEMISTRY TECHNIQUES; CYCLOSPORINE; CYTOKINES; DNA-BINDING PROTEINS; GENES, REPORTER; HAPLORHINI; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INTERLEUKIN-2; INTERLEUKIN-4; INTERLEUKIN-5; INTERLEUKIN-8; JURKAT CELLS; LEUKOCYTES, MONONUCLEAR; LUCIFERASES; NFATC TRANSCRIPTION FACTORS; NUCLEAR PROTEINS; PROTEIN SYNTHESIS INHIBITORS; PYRAZOLES; RATS; TRANSCRIPTION FACTORS;

EID: 0034632915     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm990615a     Document Type: Article

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