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Volumn 140, Issue 7, 2011, Pages 2107-2115.e4

Genetic and pharmacologic inhibition of the Ca2+ influx channel TRPC3 protects secretory epithelia from Ca2+-dependent toxicity

Author keywords

Cell Death; Inflammation; Therapeutics

Indexed keywords

CERULETIDE; PYRAZOLE DERIVATIVE; TRANSIENT RECEPTOR POTENTIAL CHANNEL 3; TRYPSIN;

EID: 79958082101     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2011.02.052     Document Type: Article
Times cited : (99)

References (47)
  • 1
    • 77549085875 scopus 로고    scopus 로고
    • Preventing Ca2+-mediated nitrosative stress in neurodegenerative diseases: Possible pharmacological strategies
    • T. Nakamura, and S.A. Lipton Preventing Ca2+-mediated nitrosative stress in neurodegenerative diseases: possible pharmacological strategies Cell Calcium 47 2010 190 197
    • (2010) Cell Calcium , vol.47 , pp. 190-197
    • Nakamura, T.1    Lipton, S.A.2
  • 2
    • 67349217063 scopus 로고    scopus 로고
    • ER and aging-protein folding and the ER stress response
    • N. Naidoo ER and aging-protein folding and the ER stress response Ageing Res Rev 8 2009 150 159
    • (2009) Ageing Res Rev , vol.8 , pp. 150-159
    • Naidoo, N.1
  • 3
    • 63849184477 scopus 로고    scopus 로고
    • Crosstalk signaling between mitochondrial Ca2+ and ROS
    • R.F. Feissner, J. Skalska, and W.E. Gaum Crosstalk signaling between mitochondrial Ca2+ and ROS Front Biosci 14 2009 1197 1218
    • (2009) Front Biosci , vol.14 , pp. 1197-1218
    • Feissner, R.F.1    Skalska, J.2    Gaum, W.E.3
  • 5
    • 67349247568 scopus 로고    scopus 로고
    • Fatty acids, alcohol and fatty acid ethyl esters: Toxic Ca2+ signal generation and pancreatitis
    • O.H. Petersen, A.V. Tepikin, and J.V. Gerasimenko Fatty acids, alcohol and fatty acid ethyl esters: toxic Ca2+ signal generation and pancreatitis Cell Calcium 45 2009 634 642
    • (2009) Cell Calcium , vol.45 , pp. 634-642
    • Petersen, O.H.1    Tepikin, A.V.2    Gerasimenko, J.V.3
  • 6
    • 48249124906 scopus 로고    scopus 로고
    • Pancreatitis: The neglected duct
    • M.G. Lee, and S. Muallem Pancreatitis: the neglected duct Gut 57 2008 1037 1039
    • (2008) Gut , vol.57 , pp. 1037-1039
    • Lee, M.G.1    Muallem, S.2
  • 7
    • 34548731971 scopus 로고    scopus 로고
    • Cholinoreceptor autoantibodies in Sjogren syndrome
    • S. Reina, B. Orman, and J.M. Anaya Cholinoreceptor autoantibodies in Sjogren syndrome J Dent Res 86 2007 832 836
    • (2007) J Dent Res , vol.86 , pp. 832-836
    • Reina, S.1    Orman, B.2    Anaya, J.M.3
  • 8
    • 0033887738 scopus 로고    scopus 로고
    • The role of intracellular calcium signaling in premature protease activation and the onset of pancreatitis
    • B. Kruger, E. Albrecht, and M.M. Lerch The role of intracellular calcium signaling in premature protease activation and the onset of pancreatitis Am J Pathol 157 2000 43 50 (Pubitemid 30641723)
    • (2000) American Journal of Pathology , vol.157 , Issue.1 , pp. 43-50
    • Kruger, B.1    Albrecht, E.2    Lerch, M.M.3
  • 9
    • 77953727883 scopus 로고    scopus 로고
    • Cytokines in Sjogren's syndrome: Potential therapeutic targets
    • N. Roescher, P.P. Tak, and G.G. Illei Cytokines in Sjogren's syndrome: potential therapeutic targets Ann Rheum Dis 69 2010 945 948
    • (2010) Ann Rheum Dis , vol.69 , pp. 945-948
    • Roescher, N.1    Tak, P.P.2    Illei, G.G.3
  • 10
    • 69549092428 scopus 로고    scopus 로고
    • Emerging new pathways of pathogenesis and targets for treatment in systemic lupus erythematosus and Sjogren's syndrome
    • A. Perl Emerging new pathways of pathogenesis and targets for treatment in systemic lupus erythematosus and Sjogren's syndrome Curr Opin Rheumatol 21 2009 443 447
    • (2009) Curr Opin Rheumatol , vol.21 , pp. 443-447
    • Perl, A.1
  • 11
    • 33646459191 scopus 로고    scopus 로고
    • Mechanisms of disease: Primary Sjogren's syndrome and the type i interferon system
    • G. Nordmark, G.V. Alm, and L. Ronnblom Mechanisms of disease: primary Sjogren's syndrome and the type I interferon system Nat Clin Pract Rheumatol 2 2006 262 269
    • (2006) Nat Clin Pract Rheumatol , vol.2 , pp. 262-269
    • Nordmark, G.1    Alm, G.V.2    Ronnblom, L.3
  • 12
    • 77955007144 scopus 로고    scopus 로고
    • Treatment of primary Sjogren syndrome: A systematic review
    • M. Ramos-Casals, A.G. Tzioufas, and J.H. Stone Treatment of primary Sjogren syndrome: a systematic review JAMA 304 2010 452 460
    • (2010) JAMA , vol.304 , pp. 452-460
    • Ramos-Casals, M.1    Tzioufas, A.G.2    Stone, J.H.3
  • 13
    • 31844439239 scopus 로고    scopus 로고
    • 2+ signalling and pancreatitis: Effects of alcohol, bile and coffee
    • DOI 10.1016/j.tips.2005.12.006, PII S0165614705003196
    • O.H. Petersen, and R. Sutton Ca2+ signalling and pancreatitis: effects of alcohol, bile and coffee Trends Pharmacol Sci 27 2006 113 120 (Pubitemid 43184033)
    • (2006) Trends in Pharmacological Sciences , vol.27 , Issue.2 , pp. 113-120
    • Petersen, O.H.1    Sutton, R.2
  • 14
    • 33750513825 scopus 로고    scopus 로고
    • Calcium signaling complexes in microdomains of polarized secretory cells
    • DOI 10.1016/j.ceca.2006.08.009, PII S0143416006001746
    • K. Kiselyov, X. Wang, and D.M. Shin Calcium signaling complexes in microdomains of polarized secretory cells Cell Calcium 40 2006 451 459 (Pubitemid 44660716)
    • (2006) Cell Calcium , vol.40 , Issue.5-6 , pp. 451-459
    • Kiselyov, K.1    Wang, X.2    Shin, D.M.3    Zang, W.4    Muallem, S.5
  • 15
    • 70349435370 scopus 로고    scopus 로고
    • Deletion of TRPC3 in mice reduces store-operated Ca2+ influx and the severity of acute pancreatitis
    • M.S. Kim, J.H. Hong, and Q. Li Deletion of TRPC3 in mice reduces store-operated Ca2+ influx and the severity of acute pancreatitis Gastroenterology 137 2009 1509 1517
    • (2009) Gastroenterology , vol.137 , pp. 1509-1517
    • Kim, M.S.1    Hong, J.H.2    Li, Q.3
  • 17
    • 15544368216 scopus 로고    scopus 로고
    • Store-operated calcium channels
    • DOI 10.1152/physrev.00057.2003
    • A.B. Parekh, and J.W. Putney Jr Store-operated calcium channels Physiol Rev 85 2005 757 810 (Pubitemid 40404641)
    • (2005) Physiological Reviews , vol.85 , Issue.2 , pp. 757-810
    • Parekh, A.B.1    Putney Jr., J.W.2
  • 18
    • 15544391158 scopus 로고    scopus 로고
    • Regulation of fluid and electrolyte secretion in salivary gland acinar cells
    • DOI 10.1146/annurev.physiol.67.041703.084745
    • J.E. Melvin, D. Yule, and T. Shuttleworth Regulation of fluid and electrolyte secretion in salivary gland acinar cells Annu Rev Physiol 67 2005 445 469 (Pubitemid 40404496)
    • (2005) Annual Review of Physiology , vol.67 , pp. 445-469
    • Melvin, J.E.1    Yule, D.2    Shuttleworth, T.3    Begenisich, T.4
  • 19
    • 42549104954 scopus 로고    scopus 로고
    • Pancreatitis and calcium signalling: Report of an international workshop
    • R. Sutton, O.H. Petersen, and S.J. Pandol Pancreatitis and calcium signalling: report of an international workshop Pancreas 36 2008 e1 e14
    • (2008) Pancreas , vol.36
    • Sutton, R.1    Petersen, O.H.2    Pandol, S.J.3
  • 20
    • 33750508965 scopus 로고    scopus 로고
    • 2+ channels and regulation of calcium microdomains
    • DOI 10.1016/j.ceca.2006.08.011, PII S014341600600176X
    • I.S. Ambudkar, B.C. Bandyopadhyay, and X. Liu Functional organization of TRPC-Ca2+ channels and regulation of calcium microdomains Cell Calcium 40 2006 495 504 (Pubitemid 44660718)
    • (2006) Cell Calcium , vol.40 , Issue.5-6 , pp. 495-504
    • Ambudkar, I.S.1    Bandyopadhyay, B.C.2    Liu, X.3    Lockwich, T.P.4    Paria, B.5    Ong, H.L.6
  • 22
    • 70349786480 scopus 로고    scopus 로고
    • Ribosome-free terminals of rough ER allow formation of STIM1 puncta and segregation of STIM1 from IP(3) receptors
    • G. Lur, L.P. Haynes, and I.A. Prior Ribosome-free terminals of rough ER allow formation of STIM1 puncta and segregation of STIM1 from IP(3) receptors Curr Biol 19 2009 1648 1653
    • (2009) Curr Biol , vol.19 , pp. 1648-1653
    • Lur, G.1    Haynes, L.P.2    Prior, I.A.3
  • 23
    • 77953915273 scopus 로고    scopus 로고
    • Effect of cell swelling on ER/PM junctional interactions and channel assembly involved in SOCE
    • X. Liu, H.L. Ong, and B. Pani Effect of cell swelling on ER/PM junctional interactions and channel assembly involved in SOCE Cell Calcium 47 2010 491 499
    • (2010) Cell Calcium , vol.47 , pp. 491-499
    • Liu, X.1    Ong, H.L.2    Pani, B.3
  • 24
    • 33846807748 scopus 로고    scopus 로고
    • Transient receptor potential cation channels in disease
    • DOI 10.1152/physrev.00021.2006
    • B. Nilius, G. Owsianik, and T. Voets Transient receptor potential cation channels in disease Physiol Rev 87 2007 165 217 (Pubitemid 46207713)
    • (2007) Physiological Reviews , vol.87 , Issue.1 , pp. 165-217
    • Nilius, B.1    Owsianik, G.2    Voets, T.3    Peters, J.A.4
  • 25
    • 67349155932 scopus 로고    scopus 로고
    • Cellular stress/the unfolded protein response: Relevance to sleep and sleep disorders
    • N. Naidoo Cellular stress/the unfolded protein response: relevance to sleep and sleep disorders Sleep Med Rev 13 2009 195 204
    • (2009) Sleep Med Rev , vol.13 , pp. 195-204
    • Naidoo, N.1
  • 26
    • 77952668956 scopus 로고    scopus 로고
    • An endoplasmic reticulum/plasma membrane junction: STIM1/Orai1/TRPCs
    • K.P. Lee, J.P. Yuan, and J.H. Hong An endoplasmic reticulum/plasma membrane junction: STIM1/Orai1/TRPCs FEBS Lett 584 2010 2022 2027
    • (2010) FEBS Lett , vol.584 , pp. 2022-2027
    • Lee, K.P.1    Yuan, J.P.2    Hong, J.H.3
  • 28
    • 65249173997 scopus 로고    scopus 로고
    • Selective and direct inhibition of TRPC3 channels underlies biological activities of a pyrazole compound
    • S. Kiyonaka, K. Kato, and M. Nishida Selective and direct inhibition of TRPC3 channels underlies biological activities of a pyrazole compound Proc Natl Acad Sci U S A 106 2009 5400 5405
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 5400-5405
    • Kiyonaka, S.1    Kato, K.2    Nishida, M.3
  • 30
    • 33947376068 scopus 로고    scopus 로고
    • Why does pancreatic overstimulation cause pancreatitis?
    • DOI 10.1146/annurev.physiol.69.031905.161253
    • A.K. Saluja, M.M. Lerch, and P.A. Phillips Why does pancreatic overstimulation cause pancreatitis? Annu Rev Physiol 69 2007 249 269 (Pubitemid 46457643)
    • (2007) Annual Review of Physiology , vol.69 , pp. 249-269
    • Saluja, A.K.1    Lerch, M.M.2    Phillips, P.A.3    Dudeja, V.4
  • 31
    • 70449426665 scopus 로고    scopus 로고
    • Impaired autophagic flux mediates acinar cell vacuole formation and trypsinogen activation in rodent models of acute pancreatitis
    • O.A. Mareninova, K. Hermann, and S.W. French Impaired autophagic flux mediates acinar cell vacuole formation and trypsinogen activation in rodent models of acute pancreatitis J Clin Invest 119 2009 3340 3355
    • (2009) J Clin Invest , vol.119 , pp. 3340-3355
    • Mareninova, O.A.1    Hermann, K.2    French, S.W.3
  • 33
    • 34447097610 scopus 로고    scopus 로고
    • STIM1 heteromultimerizes TRPC channels to determine their function as store-operated channels
    • DOI 10.1038/ncb1590, PII NCB1590
    • J.P. Yuan, W. Zeng, and G.N. Huang STIM1 heteromultimerizes TRPC channels to determine their function as store-operated channels Nat Cell Biol 9 2007 636 645 (Pubitemid 47214725)
    • (2007) Nature Cell Biology , vol.9 , Issue.6 , pp. 636-645
    • Yuan, J.P.1    Zeng, W.2    Huang, G.N.3    Worley, P.F.4    Muallem, S.5
  • 34
    • 20444364145 scopus 로고    scopus 로고
    • Molecular analysis of a store-operated and 2-acetyl-sn-glycerol-sensitive non-selective cation channel: Heteromeric assembly of TRPC1-TRPC3
    • DOI 10.1074/jbc.C400492200
    • X. Liu, B.C. Bandyopadhyay, and B.B. Singh Molecular analysis of a store-operated and 2-acetyl-sn-glycerol-sensitive non-selective cation channel Heteromeric assembly of TRPC1-TRPC3 J Biol Chem 280 2005 21600 21606 (Pubitemid 40805728)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.22 , pp. 21600-21606
    • Liu, X.1    Bandyopadhyay, B.C.2    Singh, B.B.3    Groschner, K.4    Ambudkar, I.S.5
  • 35
    • 69749123786 scopus 로고    scopus 로고
    • Fine-tuning of the unfolded protein response: Assembling the IRE1alpha interactome
    • C. Hetz, and L.H. Glimcher Fine-tuning of the unfolded protein response: assembling the IRE1alpha interactome Mol Cell 35 2009 551 561
    • (2009) Mol Cell , vol.35 , pp. 551-561
    • Hetz, C.1    Glimcher, L.H.2
  • 36
    • 66449115318 scopus 로고    scopus 로고
    • Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells
    • M. Salazar, A. Carracedo, and I.J. Salanueva Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells J Clin Invest 119 2009 1359 1372
    • (2009) J Clin Invest , vol.119 , pp. 1359-1372
    • Salazar, M.1    Carracedo, A.2    Salanueva, I.J.3
  • 37
    • 40749083610 scopus 로고    scopus 로고
    • Cholesterol and sphingolipids in alcohol-induced liver injury
    • A. Fernandez, A. Colell, and C. Garcia-Ruiz Cholesterol and sphingolipids in alcohol-induced liver injury J Gastroenterol Hepatol 23 Suppl 1 2008 S9 S15
    • (2008) J Gastroenterol Hepatol , vol.23 , Issue.SUPPL. 1
    • Fernandez, A.1    Colell, A.2    Garcia-Ruiz, C.3
  • 38
    • 59649124211 scopus 로고    scopus 로고
    • The TRPC class of ion channels: A critical review of their roles in slow, sustained increases in intracellular Ca(2+) concentrations
    • L. Birnbaumer The TRPC class of ion channels: a critical review of their roles in slow, sustained increases in intracellular Ca(2+) concentrations Annu Rev Pharmacol Toxicol 49 2009 395 426
    • (2009) Annu Rev Pharmacol Toxicol , vol.49 , pp. 395-426
    • Birnbaumer, L.1
  • 39
    • 78651094967 scopus 로고    scopus 로고
    • Polarized but differential localization and recruitment of STIM1, Orai1 and TRPC channels in secretory cells
    • J.H. Hong, Q. Li, and M.S. Kim Polarized but differential localization and recruitment of STIM1, Orai1 and TRPC channels in secretory cells Traffic 12 2011 232 245
    • (2011) Traffic , vol.12 , pp. 232-245
    • Hong, J.H.1    Li, Q.2    Kim, M.S.3
  • 41
    • 39549112572 scopus 로고    scopus 로고
    • Polarized calcium signaling in exocrine gland cells
    • DOI 10.1146/annurev.physiol.70.113006.100618
    • O.H. Petersen, and A.V. Tepikin Polarized calcium signaling in exocrine gland cells Annu Rev Physiol 70 2008 273 299 (Pubitemid 351738181)
    • (2008) Annual Review of Physiology , vol.70 , pp. 273-299
    • Petersen, O.H.1    Tepikin, A.V.2
  • 42
    • 0345601991 scopus 로고    scopus 로고
    • 2+ signaling in non-excitable cells
    • DOI 10.1016/S0143-4160(03)00150-7
    • J.I. Bruce, S.V. Straub, and D.I. Yule Crosstalk between cAMP and Ca2+ signaling in non-excitable cells Cell Calcium 34 2003 431 444 (Pubitemid 37493341)
    • (2003) Cell Calcium , vol.34 , Issue.6 , pp. 431-444
    • Bruce, J.I.E.1    Straub, S.V.2    Yule, D.I.3
  • 43
    • 77953911768 scopus 로고    scopus 로고
    • Linking structure to function: Recent lessons from inositol 1,4,5-trisphosphate receptor mutagenesis
    • D.I. Yule, M.J. Betzenhauser, and S.K. Joseph Linking structure to function: recent lessons from inositol 1,4,5-trisphosphate receptor mutagenesis Cell Calcium 47 2010 469 479
    • (2010) Cell Calcium , vol.47 , pp. 469-479
    • Yule, D.I.1    Betzenhauser, M.J.2    Joseph, S.K.3
  • 44
    • 70349435370 scopus 로고    scopus 로고
    • Deletion of TRPC3 in mice reduces store-operated Ca2+ influx and the severity of acute pancreatitis
    • M.S. Kim, J.H. Hong, and Q. Li Deletion of TRPC3 in mice reduces store-operated Ca2+ influx and the severity of acute pancreatitis Gastroenterology 137 2009 1509 1517
    • (2009) Gastroenterology , vol.137 , pp. 1509-1517
    • Kim, M.S.1    Hong, J.H.2    Li, Q.3
  • 45
    • 0033887738 scopus 로고    scopus 로고
    • The role of intracellular calcium signaling in premature protease activation and the onset of pancreatitis
    • B. Kruger, E. Albrecht, and M.M. Lerch The role of intracellular calcium signaling in premature protease activation and the onset of pancreatitis Am J Pathol 157 2000 43 50 (Pubitemid 30641723)
    • (2000) American Journal of Pathology , vol.157 , Issue.1 , pp. 43-50
    • Kruger, B.1    Albrecht, E.2    Lerch, M.M.3
  • 47
    • 70149111268 scopus 로고    scopus 로고
    • Molecular determinants of fast Ca2+-dependent inactivation and gating of the Orai channels
    • K.P. Lee, J.P. Yuan, and W. Zeng Molecular determinants of fast Ca2+-dependent inactivation and gating of the Orai channels Proc Natl Acad Sci U S A 106 2009 14687 14692
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 14687-14692
    • Lee, K.P.1    Yuan, J.P.2    Zeng, W.3


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