Molecular determinants of regulatory T cell development: The essential roles of epigenetic changes

Frontiers in Immunology

Volumn 4, Issue MAY, 2013, Pages

  Kitagawa, Yohko ^a   Ohkura, Naganari ^a   Sakaguchi, Shimon ^a,b  

^a OSAKA UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

Adaptability; DNA methylation; Epigenetics; Foxp3; Lineage specification; Plasticity; Regulatory T cells

Indexed keywords

CD4 ANTIGEN; CD45RA ANTIGEN; CD45RB ANTIGEN; CHEMOKINE RECEPTOR CXCR3; GAMMA INTERFERON; INTERFERON REGULATORY FACTOR 4; INTERLEUKIN 12; INTERLEUKIN 2; NUCLEAR RECEPTOR RELATED FACTOR 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN BCL 6; RNA POLYMERASE; SMAD3 PROTEIN; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR FOXP3; TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR NFAT; TRANSCRIPTION FACTOR RUNX1; TRANSFORMING GROWTH FACTOR BETA;

AUTOIMMUNE DISEASE; CELL DIFFERENTIATION; CELL LINEAGE; CELL MATURATION; DNA METHYLATION; EPIGENETICS; GENE EXPRESSION; GENETIC TRANSCRIPTION; HISTONE MODIFICATION; HOMEOSTASIS; HUMAN; IMMUNOLOGICAL TOLERANCE; NONHUMAN; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; REVIEW; SIGNAL TRANSDUCTION;

EID: 84883746004     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2013.00106     Document Type: Review

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