메뉴 건너뛰기




Volumn 37, Issue 3, 2012, Pages 501-510

T-bet+ Treg Cells Undergo Abortive Th1 Cell Differentiation due to Impaired Expression of IL-12 Receptor β2

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 12 RECEPTOR BETA2; STAT1 PROTEIN; TRANSCRIPTION FACTOR FOXP3; TRANSCRIPTION FACTOR T BET;

EID: 84866499256     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2012.05.031     Document Type: Article
Times cited : (199)

References (46)
  • 2
    • 35548973389 scopus 로고    scopus 로고
    • Contribution of IL-12R mediated feedback loop to Th1 cell differentiation
    • Becskei A., Grusby M.J. Contribution of IL-12R mediated feedback loop to Th1 cell differentiation. FEBS Lett. 2007, 581:5199-5206.
    • (2007) FEBS Lett. , vol.581 , pp. 5199-5206
    • Becskei, A.1    Grusby, M.J.2
  • 4
    • 79251500661 scopus 로고    scopus 로고
    • Phenotypical and functional specialization of FOXP3+ regulatory T cells
    • Campbell D.J., Koch M.A. Phenotypical and functional specialization of FOXP3+ regulatory T cells. Nat. Rev. Immunol. 2011, 11:119-130.
    • (2011) Nat. Rev. Immunol. , vol.11 , pp. 119-130
    • Campbell, D.J.1    Koch, M.A.2
  • 7
  • 9
    • 34548644772 scopus 로고    scopus 로고
    • The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing
    • De Santa F., Totaro M.G., Prosperini E., Notarbartolo S., Testa G., Natoli G. The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing. Cell 2007, 130:1083-1094.
    • (2007) Cell , vol.130 , pp. 1083-1094
    • De Santa, F.1    Totaro, M.G.2    Prosperini, E.3    Notarbartolo, S.4    Testa, G.5    Natoli, G.6
  • 10
    • 79958130907 scopus 로고    scopus 로고
    • Interleukin-12 converts Foxp3+ regulatory T cells to interferon-γ-producing Foxp3+ T cells that inhibit colitis
    • Feng T., Cao A.T., Weaver C.T., Elson C.O., Cong Y. Interleukin-12 converts Foxp3+ regulatory T cells to interferon-γ-producing Foxp3+ T cells that inhibit colitis. Gastroenterology 2011, 140:2031-2043.
    • (2011) Gastroenterology , vol.140 , pp. 2031-2043
    • Feng, T.1    Cao, A.T.2    Weaver, C.T.3    Elson, C.O.4    Cong, Y.5
  • 11
    • 0027336689 scopus 로고
    • Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages
    • Hsieh C.S., Macatonia S.E., Tripp C.S., Wolf S.F., O'Garra A., Murphy K.M. Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages. Science 1993, 260:547-549.
    • (1993) Science , vol.260 , pp. 547-549
    • Hsieh, C.S.1    Macatonia, S.E.2    Tripp, C.S.3    Wolf, S.F.4    O'Garra, A.5    Murphy, K.M.6
  • 13
    • 34548027000 scopus 로고    scopus 로고
    • Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor
    • Joshi N.S., Cui W., Chandele A., Lee H.K., Urso D.R., Hagman J., Gapin L., Kaech S.M. Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor. Immunity 2007, 27:281-295.
    • (2007) Immunity , vol.27 , pp. 281-295
    • Joshi, N.S.1    Cui, W.2    Chandele, A.3    Lee, H.K.4    Urso, D.R.5    Hagman, J.6    Gapin, L.7    Kaech, S.M.8
  • 14
    • 65749103365 scopus 로고    scopus 로고
    • The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation
    • Koch M.A., Tucker-Heard G., Perdue N.R., Killebrew J.R., Urdahl K.B., Campbell D.J. The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation. Nat. Immunol. 2009, 10:595-602.
    • (2009) Nat. Immunol. , vol.10 , pp. 595-602
    • Koch, M.A.1    Tucker-Heard, G.2    Perdue, N.R.3    Killebrew, J.R.4    Urdahl, K.B.5    Campbell, D.J.6
  • 16
    • 33947177232 scopus 로고    scopus 로고
    • Chromatin remodeling by the SWI/SNF-like BAF complex and STAT4 activation synergistically induce IL-12Rbeta2 expression during human Th1 cell differentiation
    • Letimier F.A., Passini N., Gasparian S., Bianchi E., Rogge L. Chromatin remodeling by the SWI/SNF-like BAF complex and STAT4 activation synergistically induce IL-12Rbeta2 expression during human Th1 cell differentiation. EMBO J. 2007, 26:1292-1302.
    • (2007) EMBO J. , vol.26 , pp. 1292-1302
    • Letimier, F.A.1    Passini, N.2    Gasparian, S.3    Bianchi, E.4    Rogge, L.5
  • 17
    • 79953070839 scopus 로고    scopus 로고
    • Becoming self-aware: the thymic education of regulatory T cells
    • Lio C.W., Hsieh C.S. Becoming self-aware: the thymic education of regulatory T cells. Curr. Opin. Immunol. 2011, 23:213-219.
    • (2011) Curr. Opin. Immunol. , vol.23 , pp. 213-219
    • Lio, C.W.1    Hsieh, C.S.2
  • 19
    • 0027409793 scopus 로고
    • Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells
    • Manetti R., Parronchi P., Giudizi M.G., Piccinni M.P., Maggi E., Trinchieri G., Romagnani S. Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells. J. Exp. Med. 1993, 177:1199-1204.
    • (1993) J. Exp. Med. , vol.177 , pp. 1199-1204
    • Manetti, R.1    Parronchi, P.2    Giudizi, M.G.3    Piccinni, M.P.4    Maggi, E.5    Trinchieri, G.6    Romagnani, S.7
  • 21
    • 23844478869 scopus 로고    scopus 로고
    • Natural recovery and protection from autoimmune encephalomyelitis: contribution of CD4+CD25+ regulatory cells within the central nervous system
    • McGeachy M.J., Stephens L.A., Anderton S.M. Natural recovery and protection from autoimmune encephalomyelitis: contribution of CD4+CD25+ regulatory cells within the central nervous system. J. Immunol. 2005, 175:3025-3032.
    • (2005) J. Immunol. , vol.175 , pp. 3025-3032
    • McGeachy, M.J.1    Stephens, L.A.2    Anderton, S.M.3
  • 22
    • 34447580869 scopus 로고    scopus 로고
    • Gut flora antigens are not important in the maintenance of regulatory T cell heterogeneity and homeostasis
    • Min B., Thornton A., Caucheteux S.M., Younes S.A., Oh K., Hu-Li J., Paul W.E. Gut flora antigens are not important in the maintenance of regulatory T cell heterogeneity and homeostasis. Eur. J. Immunol. 2007, 37:1916-1923.
    • (2007) Eur. J. Immunol. , vol.37 , pp. 1916-1923
    • Min, B.1    Thornton, A.2    Caucheteux, S.M.3    Younes, S.A.4    Oh, K.5    Hu-Li, J.6    Paul, W.E.7
  • 23
    • 84857416489 scopus 로고    scopus 로고
    • Plasticity of Foxp3(+) T cells reflects promiscuous Foxp3 expression in conventional T cells but not reprogramming of regulatory T cells
    • Miyao T., Floess S., Setoguchi R., Luche H., Fehling H.J., Waldmann H., Huehn J., Hori S. Plasticity of Foxp3(+) T cells reflects promiscuous Foxp3 expression in conventional T cells but not reprogramming of regulatory T cells. Immunity 2012, 36:262-275.
    • (2012) Immunity , vol.36 , pp. 262-275
    • Miyao, T.1    Floess, S.2    Setoguchi, R.3    Luche, H.4    Fehling, H.J.5    Waldmann, H.6    Huehn, J.7    Hori, S.8
  • 25
    • 35349024802 scopus 로고    scopus 로고
    • CXCR3 signaling reduces the severity of experimental autoimmune encephalomyelitis by controlling the parenchymal distribution of effector and regulatory T cells in the central nervous system
    • Müller M., Carter S.L., Hofer M.J., Manders P., Getts D.R., Getts M.T., Dreykluft A., Lu B., Gerard C., King N.J., Campbell I.L. CXCR3 signaling reduces the severity of experimental autoimmune encephalomyelitis by controlling the parenchymal distribution of effector and regulatory T cells in the central nervous system. J. Immunol. 2007, 179:2774-2786.
    • (2007) J. Immunol. , vol.179 , pp. 2774-2786
    • Müller, M.1    Carter, S.L.2    Hofer, M.J.3    Manders, P.4    Getts, D.R.5    Getts, M.T.6    Dreykluft, A.7    Lu, B.8    Gerard, C.9    King, N.J.10    Campbell, I.L.11
  • 29
    • 43949105866 scopus 로고    scopus 로고
    • Regulatory T cells and immune tolerance
    • Sakaguchi S., Yamaguchi T., Nomura T., Ono M. Regulatory T cells and immune tolerance. Cell 2008, 133:775-787.
    • (2008) Cell , vol.133 , pp. 775-787
    • Sakaguchi, S.1    Yamaguchi, T.2    Nomura, T.3    Ono, M.4
  • 30
    • 65549118531 scopus 로고    scopus 로고
    • Sequential polarization and imprinting of type 1 T helper lymphocytes by interferon-gamma and interleukin-12
    • Schulz E.G., Mariani L., Radbruch A., Höfer T. Sequential polarization and imprinting of type 1 T helper lymphocytes by interferon-gamma and interleukin-12. Immunity 2009, 30:673-683.
    • (2009) Immunity , vol.30 , pp. 673-683
    • Schulz, E.G.1    Mariani, L.2    Radbruch, A.3    Höfer, T.4
  • 31
    • 0036785630 scopus 로고    scopus 로고
    • Critical roles of myeloid differentiation factor 88-dependent proinflammatory cytokine release in early phase clearance of Listeria monocytogenes in mice
    • Seki E., Tsutsui H., Tsuji N.M., Hayashi N., Adachi K., Nakano H., Futatsugi-Yumikura S., Takeuchi O., Hoshino K., Akira S., et al. Critical roles of myeloid differentiation factor 88-dependent proinflammatory cytokine release in early phase clearance of Listeria monocytogenes in mice. J. Immunol. 2002, 169:3863-3868.
    • (2002) J. Immunol. , vol.169 , pp. 3863-3868
    • Seki, E.1    Tsutsui, H.2    Tsuji, N.M.3    Hayashi, N.4    Adachi, K.5    Nakano, H.6    Futatsugi-Yumikura, S.7    Takeuchi, O.8    Hoshino, K.9    Akira, S.10
  • 32
    • 15444374646 scopus 로고    scopus 로고
    • Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization
    • Setoguchi R., Hori S., Takahashi T., Sakaguchi S. Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization. J. Exp. Med. 2005, 201:723-735.
    • (2005) J. Exp. Med. , vol.201 , pp. 723-735
    • Setoguchi, R.1    Hori, S.2    Takahashi, T.3    Sakaguchi, S.4
  • 33
    • 65549136983 scopus 로고    scopus 로고
    • Mechanisms of foxp3+ T regulatory cell-mediated suppression
    • Shevach E.M. Mechanisms of foxp3+ T regulatory cell-mediated suppression. Immunity 2009, 30:636-645.
    • (2009) Immunity , vol.30 , pp. 636-645
    • Shevach, E.M.1
  • 34
    • 8044250881 scopus 로고    scopus 로고
    • Regulation of the interleukin (IL)-12R beta 2 subunit expression in developing T helper 1 (Th1) and Th2 cells
    • Szabo S.J., Dighe A.S., Gubler U., Murphy K.M. Regulation of the interleukin (IL)-12R beta 2 subunit expression in developing T helper 1 (Th1) and Th2 cells. J. Exp. Med. 1997, 185:817-824.
    • (1997) J. Exp. Med. , vol.185 , pp. 817-824
    • Szabo, S.J.1    Dighe, A.S.2    Gubler, U.3    Murphy, K.M.4
  • 35
    • 39449126502 scopus 로고    scopus 로고
    • The Foxp3+ regulatory T cell: a jack of all trades, master of regulation
    • Tang Q., Bluestone J.A. The Foxp3+ regulatory T cell: a jack of all trades, master of regulation. Nat. Immunol. 2008, 9:239-244.
    • (2008) Nat. Immunol. , vol.9 , pp. 239-244
    • Tang, Q.1    Bluestone, J.A.2
  • 36
    • 55349117409 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription 4 is required for the transcription factor T-bet to promote T helper 1 cell-fate determination
    • Thieu V.T., Yu Q., Chang H.C., Yeh N., Nguyen E.T., Sehra S., Kaplan M.H. Signal transducer and activator of transcription 4 is required for the transcription factor T-bet to promote T helper 1 cell-fate determination. Immunity 2008, 29:679-690.
    • (2008) Immunity , vol.29 , pp. 679-690
    • Thieu, V.T.1    Yu, Q.2    Chang, H.C.3    Yeh, N.4    Nguyen, E.T.5    Sehra, S.6    Kaplan, M.H.7
  • 37
    • 0037313578 scopus 로고    scopus 로고
    • Interleukin-12 and the regulation of innate resistance and adaptive immunity
    • Trinchieri G. Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat. Rev. Immunol. 2003, 3:133-146.
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 133-146
    • Trinchieri, G.1
  • 39
    • 33947703762 scopus 로고    scopus 로고
    • IL-12 and type-I IFN synergize for IFN-gamma production by CD4 T cells, whereas neither are required for IFN-gamma production by CD8 T cells after Listeria monocytogenes infection
    • Way S.S., Havenar-Daughton C., Kolumam G.A., Orgun N.N., Murali-Krishna K. IL-12 and type-I IFN synergize for IFN-gamma production by CD4 T cells, whereas neither are required for IFN-gamma production by CD8 T cells after Listeria monocytogenes infection. J. Immunol. 2007, 178:4498-4505.
    • (2007) J. Immunol. , vol.178 , pp. 4498-4505
    • Way, S.S.1    Havenar-Daughton, C.2    Kolumam, G.A.3    Orgun, N.N.4    Murali-Krishna, K.5
  • 40
    • 58149214356 scopus 로고    scopus 로고
    • Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells
    • Wei G., Wei L., Zhu J., Zang C., Hu-Li J., Yao Z., Cui K., Kanno Y., Roh T.Y., Watford W.T., et al. Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells. Immunity 2009, 30:155-167.
    • (2009) Immunity , vol.30 , pp. 155-167
    • Wei, G.1    Wei, L.2    Zhu, J.3    Zang, C.4    Hu-Li, J.5    Yao, Z.6    Cui, K.7    Kanno, Y.8    Roh, T.Y.9    Watford, W.T.10
  • 41
    • 77953917067 scopus 로고    scopus 로고
    • Discrete roles of STAT4 and STAT6 transcription factors in tuning epigenetic modifications and transcription during T helper cell differentiation
    • Wei L., Vahedi G., Sun H.W., Watford W.T., Takatori H., Ramos H.L., Takahashi H., Liang J., Gutierrez-Cruz G., Zang C., et al. Discrete roles of STAT4 and STAT6 transcription factors in tuning epigenetic modifications and transcription during T helper cell differentiation. Immunity 2010, 32:840-851.
    • (2010) Immunity , vol.32 , pp. 840-851
    • Wei, L.1    Vahedi, G.2    Sun, H.W.3    Watford, W.T.4    Takatori, H.5    Ramos, H.L.6    Takahashi, H.7    Liang, J.8    Gutierrez-Cruz, G.9    Zang, C.10
  • 42
    • 34247271308 scopus 로고    scopus 로고
    • Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3
    • Williams L.M., Rudensky A.Y. Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3. Nat. Immunol. 2007, 8:277-284.
    • (2007) Nat. Immunol. , vol.8 , pp. 277-284
    • Williams, L.M.1    Rudensky, A.Y.2
  • 43
    • 79961139920 scopus 로고    scopus 로고
    • IFN-γ- and IL-10-expressing virus epitope-specific Foxp3(+) T reg cells in the central nervous system during encephalomyelitis
    • Zhao J., Zhao J., Fett C., Trandem K., Fleming E., Perlman S. IFN-γ- and IL-10-expressing virus epitope-specific Foxp3(+) T reg cells in the central nervous system during encephalomyelitis. J. Exp. Med. 2011, 208:1571-1577.
    • (2011) J. Exp. Med. , vol.208 , pp. 1571-1577
    • Zhao, J.1    Zhao, J.2    Fett, C.3    Trandem, K.4    Fleming, E.5    Perlman, S.6
  • 44
    • 33847220736 scopus 로고    scopus 로고
    • Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells
    • Zheng Y., Josefowicz S.Z., Kas A., Chu T.T., Gavin M.A., Rudensky A.Y. Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells. Nature 2007, 445:936-940.
    • (2007) Nature , vol.445 , pp. 936-940
    • Zheng, Y.1    Josefowicz, S.Z.2    Kas, A.3    Chu, T.T.4    Gavin, M.A.5    Rudensky, A.Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.