-
1
-
-
33744782285
-
Inhibition of osteoblast differentiation but not adipocyte differentiation of mesenchymal stem cells by sera obtained from aged females
-
16530029 10.1016/j.bone.2005.12.082
-
Abdallah BM, Haack-Sorensen M, Fink T and Kassem M 2006 Inhibition of osteoblast differentiation but not adipocyte differentiation of mesenchymal stem cells by sera obtained from aged females. Bone 39 181-188
-
(2006)
Bone
, vol.39
, pp. 181-188
-
-
Abdallah, B.M.1
Haack-Sorensen, M.2
Fink, T.3
Kassem, M.4
-
2
-
-
37749033958
-
Human mesenchymal stem cells: From basic biology to clinical applications
-
17989700 1:CAS:528:DC%2BD1cXhtlGqug%3D%3D 10.1038/sj.gt.3303067
-
Abdallah BM and Kassem M 2008 Human mesenchymal stem cells: from basic biology to clinical applications. Gene Ther. 15 109-116
-
(2008)
Gene Ther.
, vol.15
, pp. 109-116
-
-
Abdallah, B.M.1
Kassem, M.2
-
3
-
-
58149149508
-
The use of mesenchymal (skeletal) stem cells for treatment of degenerative diseases: Current status and future perspectives
-
18726996 1:CAS:528:DC%2BD1cXhsFahsbnK 10.1002/jcp.21572
-
Abdallah BM and Kassem M 2009 The use of mesenchymal (skeletal) stem cells for treatment of degenerative diseases: current status and future perspectives. J. Cell Physiol. 218 9-12
-
(2009)
J. Cell Physiol.
, vol.218
, pp. 9-12
-
-
Abdallah, B.M.1
Kassem, M.2
-
4
-
-
0342359187
-
MTert expression correlates with telomerase activity during the differentiation of murine embryonic stem cells
-
11025212 1:CAS:528:DC%2BD3cXntF2qu74%3D 10.1016/S0925-4773(00)00423-8
-
Armstrong L, Lako M, Lincoln J, Cairns PM and Hole N 2000 mTert expression correlates with telomerase activity during the differentiation of murine embryonic stem cells. Mech. Dev. 97 109-116
-
(2000)
Mech. Dev.
, vol.97
, pp. 109-116
-
-
Armstrong, L.1
Lako, M.2
Lincoln, J.3
Cairns, P.M.4
Hole, N.5
-
5
-
-
0034632717
-
Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice
-
10949306 1:STN:280:DC%2BD3cvjtVKrug%3D%3D 10.1038/35020592
-
Artandi SE, Chang S, Lee SL, Alson S, Gottlieb GJ, Chin L and DePinho RA 2000 Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice. Nature 406 641-645
-
(2000)
Nature
, vol.406
, pp. 641-645
-
-
Artandi, S.E.1
Chang, S.2
Lee, S.L.3
Alson, S.4
Gottlieb, G.J.5
Chin, L.6
Depinho, R.A.7
-
6
-
-
84863328156
-
Age-related cognitive decline: Can neural stem cells help us?
-
22466406
-
Artegiani B and Calegari F 2012 Age-related cognitive decline: can neural stem cells help us? Aging 4 176-186
-
(2012)
Aging
, vol.4
, pp. 176-186
-
-
Artegiani, B.1
Calegari, F.2
-
7
-
-
13944278132
-
Mitochondria, oxidants, and aging
-
15734681 1:CAS:528:DC%2BD2MXitVWnurg%3D 10.1016/j.cell.2005.02.001
-
Balaban RS, Nemoto S and Finkel T 2005 Mitochondria, oxidants, and aging. Cell 120 483-495
-
(2005)
Cell
, vol.120
, pp. 483-495
-
-
Balaban, R.S.1
Nemoto, S.2
Finkel, T.3
-
8
-
-
37649026269
-
Adult bone marrow stem cells for cell and gene therapies: Implications for greater use
-
12046846 10.1002/jcb.10127 1:CAS:528:DC%2BD38XjsFaru7g%3D
-
Ballas CB, Zielske SP and Gerson SL 2002 Adult bone marrow stem cells for cell and gene therapies: implications for greater use. J. Cell Biochem. Suppl. 38 20-28
-
(2002)
J. Cell Biochem. Suppl.
, vol.38
, pp. 20-28
-
-
Ballas, C.B.1
Zielske, S.P.2
Gerson, S.L.3
-
9
-
-
4444273090
-
Study of telomere length reveals rapid aging of human marrow stromal cells following in vitro expansion
-
15342932 1:CAS:528:DC%2BD2cXnvFOlur8%3D 10.1634/stemcells.22-5-675
-
Baxter MA, Wynn RF, Jowitt SN, Wraith JE, Fairbairn LJ and Bellantuono I 2004 Study of telomere length reveals rapid aging of human marrow stromal cells following in vitro expansion. Stem Cells 22 675-682
-
(2004)
Stem Cells
, vol.22
, pp. 675-682
-
-
Baxter, M.A.1
Wynn, R.F.2
Jowitt, S.N.3
Wraith, J.E.4
Fairbairn, L.J.5
Bellantuono, I.6
-
10
-
-
0034988303
-
Bone marrow stromal stem cells: Nature, biology, and potential applications
-
11359943 1:STN:280:DC%2BD3MzlvVamsw%3D%3D 10.1634/stemcells.19-3-180
-
Bianco P, Riminucci M, Gronthos S and Robey PG 2001 Bone marrow stromal stem cells: nature, biology, and potential applications. Stem Cells 19 180-192
-
(2001)
Stem Cells
, vol.19
, pp. 180-192
-
-
Bianco, P.1
Riminucci, M.2
Gronthos, S.3
Robey, P.G.4
-
11
-
-
0021173911
-
Telomeres: Do the ends justify the means?
-
6722877 1:CAS:528:DyaL2cXktVWlt78%3D 10.1016/0092-8674(84)90295-2
-
Blackburn EH 1984 Telomeres: do the ends justify the means? Cell 37 7-8
-
(1984)
Cell
, vol.37
, pp. 7-8
-
-
Blackburn, E.H.1
-
12
-
-
0019522449
-
Non-nucleosomal packaging of a tandemly repeated DNA sequence at termini of extrachromosomal DNA coding for rRNA in Tetrahymena
-
6941283 1:CAS:528:DyaL3MXktVajt78%3D 10.1073/pnas.78.4.2263
-
Blackburn EH and Chiou SS 1981 Non-nucleosomal packaging of a tandemly repeated DNA sequence at termini of extrachromosomal DNA coding for rRNA in Tetrahymena. Proc. Natl. Acad. Sci. USA 78 2263-2267
-
(1981)
Proc. Natl. Acad. Sci. USA
, vol.78
, pp. 2263-2267
-
-
Blackburn, E.H.1
Chiou, S.S.2
-
13
-
-
0017833637
-
A tandemly repeated sequence at the termini of the extrachromosomal ribosomal RNA genes in Tetrahymena
-
642006 1:CAS:528:DyaE1cXktVejsbc%3D 10.1016/0022-2836(78)90294-2
-
Blackburn EH and Gall JG 1978 A tandemly repeated sequence at the termini of the extrachromosomal ribosomal RNA genes in Tetrahymena. J. Mol. Biol. 120 33-53
-
(1978)
J. Mol. Biol.
, vol.120
, pp. 33-53
-
-
Blackburn, E.H.1
Gall, J.G.2
-
14
-
-
22944488871
-
Telomeres and human disease: Ageing, cancer and beyond
-
16136653 1:CAS:528:DC%2BD2MXntFeqtbw%3D 10.1038/nrg1656
-
Blasco MA 2005 Telomeres and human disease: ageing, cancer and beyond. Nat. Rev. Genet. 6 611-622
-
(2005)
Nat. Rev. Genet.
, vol.6
, pp. 611-622
-
-
Blasco, M.A.1
-
15
-
-
0030931491
-
Telomere shortening and tumor formation by mouse cells lacking telomerase RNA
-
9335332 1:CAS:528:DyaK2sXmslGgt7w%3D 10.1016/S0092-8674(01)80006-4
-
Blasco MA, Lee HW, Hande MP, Samper E, Lansdorp PM, DePinho RA and Greider CW 1997 Telomere shortening and tumor formation by mouse cells lacking telomerase RNA. Cell 91 25-34
-
(1997)
Cell
, vol.91
, pp. 25-34
-
-
Blasco, M.A.1
Lee, H.W.2
Hande, M.P.3
Samper, E.4
Lansdorp, P.M.5
Depinho, R.A.6
Greider, C.W.7
-
16
-
-
34547564441
-
Bone marrow-derived cells: The influence of aging and cellular senescence
-
10.1007/978-3-540-68976-8-4
-
Beausejour C 2011 Bone marrow-derived cells: the influence of aging and cellular senescence. Handbook Expe Pharmacol. 180 67-88
-
(2011)
Handbook Expe Pharmacol.
, vol.180
, pp. 67-88
-
-
Beausejour, C.1
-
17
-
-
13944270339
-
Senescent cells, tumor suppression, and organismal aging: Good citizens, bad neighbors
-
15734683 1:CAS:528:DC%2BD2MXitVWnu74%3D 10.1016/j.cell.2005.02.003
-
Campisi J 2005 Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors. Cell 120 513-522
-
(2005)
Cell
, vol.120
, pp. 513-522
-
-
Campisi, J.1
-
18
-
-
77952097368
-
Hemato-vascular origins of endothelial progenitor cells?
-
20149806 1:CAS:528:DC%2BC3cXkvFKrur4%3D 10.1016/j.mvr.2010.02.003
-
Chao H and Hirschi KK 2010 Hemato-vascular origins of endothelial progenitor cells? Microvasc. Res. 79 169-173
-
(2010)
Microvasc. Res.
, vol.79
, pp. 169-173
-
-
Chao, H.1
Hirschi, K.K.2
-
19
-
-
84863242893
-
Human blood-vessel-derived stem cells for tissue repair and regeneration
-
22500099
-
Chen CW, Corselli M, Peault B and Huard J 2012 Human blood-vessel-derived stem cells for tissue repair and regeneration. J. Biomed. Biotechnol. 2012 597439
-
(2012)
J. Biomed. Biotechnol.
, vol.2012
, pp. 597439
-
-
Chen, C.W.1
Corselli, M.2
Peault, B.3
Huard, J.4
-
20
-
-
0029940570
-
Differential expression of telomerase activity in hematopoietic progenitors from adult human bone marrow
-
8991544 1:CAS:528:DyaK28XisV2rsb4%3D 10.1002/stem.140239
-
Chiu CP, Dragowska W, Kim NW, Vaziri H, Yui J, Thomas TE, Harley CB and Lansdorp PM 1996 Differential expression of telomerase activity in hematopoietic progenitors from adult human bone marrow. Stem Cells 14 239-248
-
(1996)
Stem Cells
, vol.14
, pp. 239-248
-
-
Chiu, C.P.1
Dragowska, W.2
Kim, N.W.3
Vaziri, H.4
Yui, J.5
Thomas, T.E.6
Harley, C.B.7
Lansdorp, P.M.8
-
21
-
-
0023034140
-
Variability at the telomeres of the human X/Y pseudoautosomal region
-
3034483 1:CAS:528:DyaL2sXkvFWisr8%3D 10.1101/SQB.1986.051.01.026
-
Cooke HJ and Smith BA 1986 Variability at the telomeres of the human X/Y pseudoautosomal region. Cold Spring Harb. Symp. Quant. Biol. 51 Pt 1 213-219
-
(1986)
Cold Spring Harb. Symp. Quant. Biol.
, vol.51
, Issue.PART 1
, pp. 213-219
-
-
Cooke, H.J.1
Smith, B.A.2
-
22
-
-
0028198679
-
Stabilization of short telomeres and telomerase activity accompany immortalization of Epstein-Barr virus-transformed human B lymphocytes
-
8151802 1:CAS:528:DyaK2cXivFGnt7Y%3D
-
Counter CM, Botelho FM, Wang P, Harley CB and Bacchetti S 1994 Stabilization of short telomeres and telomerase activity accompany immortalization of Epstein-Barr virus-transformed human B lymphocytes. J. Virol. 68 3410-3414
-
(1994)
J. Virol.
, vol.68
, pp. 3410-3414
-
-
Counter, C.M.1
Botelho, F.M.2
Wang, P.3
Harley, C.B.4
Bacchetti, S.5
-
23
-
-
0036198604
-
SV40 T antigen and telomerase are required to obtain immortalized human adult bone cells without loss of the differentiated phenotype
-
11864909 1:CAS:528:DC%2BD38XitVGntbs%3D
-
Darimont C, Avanti O, Tromvoukis Y, Vautravers-Leone P, Kurihara N, Roodman GD, Colgin LM, Tullberg-Reinert H, Pfeifer AM, Offord EA and Mace K 2002 SV40 T antigen and telomerase are required to obtain immortalized human adult bone cells without loss of the differentiated phenotype. Cell Growth Differ. 13 59-67
-
(2002)
Cell Growth Differ.
, vol.13
, pp. 59-67
-
-
Darimont, C.1
Avanti, O.2
Tromvoukis, Y.3
Vautravers-Leone, P.4
Kurihara, N.5
Roodman, G.D.6
Colgin, L.M.7
Tullberg-Reinert, H.8
Pfeifer, A.M.9
Offord, E.A.10
Mace, K.11
-
24
-
-
0042413392
-
Reconstitution of telomerase activity combined with HPV-E7 expression allow human preadipocytes to preserve their differentiation capacity after immortalization
-
12934077 1:CAS:528:DC%2BD3sXmsFeju7Y%3D 10.1038/sj.cdd.4401273
-
Darimont C, Zbinden I, Avanti O, Leone-Vautravers P, Giusti V, Burckhardt P, Pfeifer AM and Mace K 2003 Reconstitution of telomerase activity combined with HPV-E7 expression allow human preadipocytes to preserve their differentiation capacity after immortalization. Cell Death Differ. 10 1025-1031
-
(2003)
Cell Death Differ.
, vol.10
, pp. 1025-1031
-
-
Darimont, C.1
Zbinden, I.2
Avanti, O.3
Leone-Vautravers, P.4
Giusti, V.5
Burckhardt, P.6
Pfeifer, A.M.7
Mace, K.8
-
25
-
-
0344441890
-
A DNA damage checkpoint response in telomere-initiated senescence
-
dda di FF, Reaper PM, Clay-Farrace L, Fiegler H, Carr P, von ZT, Saretzki G, Carter NP and Jackson SP 2003 A DNA damage checkpoint response in telomere-initiated senescence. Nature 426 194-198
-
(2003)
Nature
, vol.426
, pp. 194-198
-
-
Dda Di, F.F.1
Reaper, P.M.2
Clay-Farrace, L.3
Fiegler, H.4
Carr, P.5
Von, Z.T.6
Saretzki, G.7
Carter, N.P.8
Jackson, S.P.9
-
26
-
-
0029047362
-
A biomarker that identifies senescent human cells in culture and in aging skin in vivo
-
7568133 1:CAS:528:DyaK2MXosVWlur0%3D 10.1073/pnas.92.20.9363
-
Dimri GP, Lee X, Basile G, Acosta M, Scott G, Roskelley C, Medrano EE, Linskens M, Rubelj I and Pereira-Smith O 1995 A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc. Natl. Acad. Sci. USA 92 9363-9367
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 9363-9367
-
-
Dimri, G.P.1
Lee, X.2
Basile, G.3
Acosta, M.4
Scott, G.5
Roskelley, C.6
Medrano, E.E.7
Linskens, M.8
Rubelj, I.9
Pereira-Smith, O.10
-
27
-
-
0037928721
-
Telomeres and telomerase in aging, regeneration and cancer
-
12803478 1:CAS:528:DC%2BD3sXkvVeqs7w%3D
-
Djojosubroto MW, Choi YS, Lee HW and Rudolph KL 2003 Telomeres and telomerase in aging, regeneration and cancer. Mol. Cells 15 164-175
-
(2003)
Mol. Cells
, vol.15
, pp. 164-175
-
-
Djojosubroto, M.W.1
Choi, Y.S.2
Lee, H.W.3
Rudolph, K.L.4
-
28
-
-
8944258925
-
Shortened telomeres in the expanded CD28-CD8+ cell subset in HIV disease implicate replicative senescence in HIV pathogenesis
-
8828735 1:STN:280:DyaK28vis1Cnsw%3D%3D 10.1097/00002030-199607000-00001
-
Effros RB, Allsopp R, Chiu CP, Hausner MA, Hirji K, Wang L, Harley CB, Villeponteau B, West MD and Giorgi JV 1996 Shortened telomeres in the expanded CD28-CD8+ cell subset in HIV disease implicate replicative senescence in HIV pathogenesis. AIDS 10 F17-F22
-
(1996)
AIDS
, vol.10
-
-
Effros, R.B.1
Allsopp, R.2
Chiu, C.P.3
Hausner, M.A.4
Hirji, K.5
Wang, L.6
Harley, C.B.7
Villeponteau, B.8
West, M.D.9
Giorgi, J.V.10
-
29
-
-
2342507670
-
A stepwise model system for limb regeneration
-
15136146 1:CAS:528:DC%2BD2cXjsl2gtL8%3D 10.1016/j.ydbio.2004.02.016
-
Endo T, Bryant SV and Gardiner DM 2004 A stepwise model system for limb regeneration. Dev. Biol. 270 135-145
-
(2004)
Dev. Biol.
, vol.270
, pp. 135-145
-
-
Endo, T.1
Bryant, S.V.2
Gardiner, D.M.3
-
30
-
-
9444243224
-
Impact of telomerase ablation on organismal viability, aging, and tumorigenesis in mice lacking the DNA repair proteins PARP-1, Ku86, or DNA-PKcs
-
Espejel S, Klatt P, Menissier-de MJ, Martin-Caballero J, Flores JM, Taccioli G, de MG and Blasco MA 2004 Impact of telomerase ablation on organismal viability, aging, and tumorigenesis in mice lacking the DNA repair proteins PARP-1, Ku86, or DNA-PKcs. J. Cell Biol. 167 627-638
-
(2004)
J. Cell Biol.
, vol.167
, pp. 627-638
-
-
Espejel, S.1
Klatt, P.2
Menissier-De, M.J.3
Martin-Caballero, J.4
Flores, J.M.5
Taccioli, G.6
De Mg7
Blasco, M.A.8
-
31
-
-
27944445760
-
Mesenchymal stem cell aging
-
16125890 1:CAS:528:DC%2BD2MXht1GiurfO 10.1016/j.exger.2005.07.006
-
Fehrer C and Lepperdinger G 2005 Mesenchymal stem cell aging. Exp. Gerontol. 40 926-930
-
(2005)
Exp. Gerontol.
, vol.40
, pp. 926-930
-
-
Fehrer, C.1
Lepperdinger, G.2
-
32
-
-
4544256099
-
Telomere shortening and chromosomal instability abrogates proliferation of adult but not embryonic neural stem cells
-
15269166 1:CAS:528:DC%2BD2cXns1Snur0%3D 10.1242/dev.01215
-
Ferron S, Mira H, Franco S, Cano-Jaimez M, Bellmunt E, Ramirez C, Farinas I and Blasco MA 2004 Telomere shortening and chromosomal instability abrogates proliferation of adult but not embryonic neural stem cells. Development 131 4059-4070
-
(2004)
Development
, vol.131
, pp. 4059-4070
-
-
Ferron, S.1
Mira, H.2
Franco, S.3
Cano-Jaimez, M.4
Bellmunt, E.5
Ramirez, C.6
Farinas, I.7
Blasco, M.A.8
-
33
-
-
70949100121
-
Telomere shortening in neural stem cells disrupts neuronal differentiation and neuritogenesis
-
19923274 1:CAS:528:DC%2BD1MXhsVOhsLnN 10.1523/JNEUROSCI.3836-09.2009
-
Ferron SR, Marques-Torrejon MA, Mira H, Flores I, Taylor K, Blasco MA and Farinas I 2009 Telomere shortening in neural stem cells disrupts neuronal differentiation and neuritogenesis. J. Neurosci. 29 14394-14407
-
(2009)
J. Neurosci.
, vol.29
, pp. 14394-14407
-
-
Ferron, S.R.1
Marques-Torrejon, M.A.2
Mira, H.3
Flores, I.4
Taylor, K.5
Blasco, M.A.6
Farinas, I.7
-
34
-
-
0036838907
-
Mesenchymal stem cells. A potential source for skeletal repair
-
12379617
-
Fibbe WE 2002 Mesenchymal stem cells. A potential source for skeletal repair. Ann. Rheum. Dis. 61 ii29-ii31
-
(2002)
Ann. Rheum. Dis.
, vol.61
-
-
Fibbe, W.E.1
-
35
-
-
23844540299
-
Effects of telomerase and telomere length on epidermal stem cell behavior
-
16037417 1:CAS:528:DC%2BD2MXnvFylsLg%3D 10.1126/science.1115025
-
Flores I, Cayuela ML and Blasco MA 2005 Effects of telomerase and telomere length on epidermal stem cell behavior. Science 309 1253-1256
-
(2005)
Science
, vol.309
, pp. 1253-1256
-
-
Flores, I.1
Cayuela, M.L.2
Blasco, M.A.3
-
36
-
-
0036362266
-
Telomerase and differentiation in multicellular organisms: Turn it off, turn it on, and turn it off again
-
11841477 1:CAS:528:DC%2BD38Xhs1Witr4%3D 10.1046/j.1432-0436.2002.690412.x
-
Forsyth NR, Wright WE and Shay JW 2002 Telomerase and differentiation in multicellular organisms: turn it off, turn it on, and turn it off again. Differentiation 69 188-197
-
(2002)
Differentiation
, vol.69
, pp. 188-197
-
-
Forsyth, N.R.1
Wright, W.E.2
Shay, J.W.3
-
37
-
-
70349672704
-
Neuronal IGF-1 resistance reduces Abeta accumulation and protects against premature death in a model of Alzheimer's disease
-
19487308 1:CAS:528:DC%2BD1MXht1GjtLnL 10.1096/fj.09-132043
-
Freude S, Hettich MM, Schumann C, Stohr O, Koch L, Kohler C, Udelhoven M, Leeser U, et al. 2009 Neuronal IGF-1 resistance reduces Abeta accumulation and protects against premature death in a model of Alzheimer's disease. FASEB J. 23 3315-3324
-
(2009)
FASEB J.
, vol.23
, pp. 3315-3324
-
-
Freude, S.1
Hettich, M.M.2
Schumann, C.3
Stohr, O.4
Koch, L.5
Kohler, C.6
Udelhoven, M.7
Leeser, U.8
Freude, S.9
Hettich, M.M.10
Schumann, C.11
Stohr, O.12
Koch, L.13
Kohler, C.14
Udelhoven, M.15
Leeser, U.16
-
38
-
-
0035010796
-
The dynamic in vivo distribution of bone marrow-derived mesenchymal stem cells after infusion
-
11340257 1:STN:280:DC%2BD3MzotlKmsg%3D%3D 10.1159/000047856
-
Gao J, Dennis JE, Muzic RF, Lundberg M and Caplan AI 2001 The dynamic in vivo distribution of bone marrow-derived mesenchymal stem cells after infusion. Cells Tissues Organs 169 12-20
-
(2001)
Cells Tissues Organs
, vol.169
, pp. 12-20
-
-
Gao, J.1
Dennis, J.E.2
Muzic, R.F.3
Lundberg, M.4
Caplan, A.I.5
-
39
-
-
0343228751
-
Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis
-
10973262 1:CAS:528:DC%2BD3cXmsVKrsrg%3D 10.1038/79089
-
Gonzalez-Suarez E, Samper E, Flores JM and Blasco MA 2000 Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis. Nat. Genet. 26 114-117
-
(2000)
Nat. Genet.
, vol.26
, pp. 114-117
-
-
Gonzalez-Suarez, E.1
Samper, E.2
Flores, J.M.3
Blasco, M.A.4
-
40
-
-
0000146723
-
Short dysfunctional telomeres impair tumorigenesis in the INK4a (delta2/3) cancer-prone mouse
-
10338215 1:CAS:528:DyaK1MXjt1Oqsr8%3D 10.1016/S0092-8674(00)80761-8
-
Greenberg RA, Chin L, Femino A, Lee KH, Gottlieb GJ, Singer RH, Greider CW and DePinho RA 1999 Short dysfunctional telomeres impair tumorigenesis in the INK4a (delta2/3) cancer-prone mouse. Cell 97 515-525
-
(1999)
Cell
, vol.97
, pp. 515-525
-
-
Greenberg, R.A.1
Chin, L.2
Femino, A.3
Lee, K.H.4
Gottlieb, G.J.5
Singer, R.H.6
Greider, C.W.7
Depinho, R.A.8
-
41
-
-
0022402513
-
Identification of a specific telomere terminal transferase activity in Tetrahymena extracts
-
3907856 1:CAS:528:DyaL28Xot12itQ%3D%3D 10.1016/0092-8674(85)90170-9
-
Greider CW and Blackburn EH 1985 Identification of a specific telomere terminal transferase activity in Tetrahymena extracts. Cell 43 405-413
-
(1985)
Cell
, vol.43
, pp. 405-413
-
-
Greider, C.W.1
Blackburn, E.H.2
-
42
-
-
28944455294
-
Short telomeres, even in the presence of telomerase, limit tissue renewal capacity
-
16360040 1:CAS:528:DC%2BD28XptVyj 10.1016/j.cell.2005.11.020
-
Hao LY, Armanios M, Strong MA, Karim B, Feldser DM, Huso D and Greider CW 2005 Short telomeres, even in the presence of telomerase, limit tissue renewal capacity. Cell 123 1121-1131
-
(2005)
Cell
, vol.123
, pp. 1121-1131
-
-
Hao, L.Y.1
Armanios, M.2
Strong, M.A.3
Karim, B.4
Feldser, D.M.5
Huso, D.6
Greider, C.W.7
-
44
-
-
0344622606
-
The serial cultivation of human diploid cell strains
-
13905658 1:STN:280:DyaF38%2FkslSgtA%3D%3D 10.1016/0014-4827(61)90192-6
-
Hayflick L and Moorheas PS 1961 The serial cultivation of human diploid cell strains. Exp. Cell Res. 25 585-621
-
(1961)
Exp. Cell Res.
, vol.25
, pp. 585-621
-
-
Hayflick, L.1
Moorheas, P.S.2
-
45
-
-
0343750697
-
Impaired germinal center reaction in mice with short telomeres
-
10654945 1:CAS:528:DC%2BD3cXhtVSgs74%3D 10.1093/emboj/19.3.472
-
Herrera E, Martinez A and Blasco MA 2000 Impaired germinal center reaction in mice with short telomeres. EMBO J. 19 472-481
-
(2000)
EMBO J.
, vol.19
, pp. 472-481
-
-
Herrera, E.1
Martinez, A.2
Blasco, M.A.3
-
46
-
-
0033153424
-
Disease states associated with telomerase deficiency appear earlier in mice with short telomeres
-
10357808 1:CAS:528:DyaK1MXktFCjtLw%3D 10.1093/emboj/18.11.2950
-
Herrera E, Samper E, Martin-Caballero J, Flores JM, Lee HW and Blasco MA 1999 Disease states associated with telomerase deficiency appear earlier in mice with short telomeres. EMBO J. 18 2950-2960
-
(1999)
EMBO J.
, vol.18
, pp. 2950-2960
-
-
Herrera, E.1
Samper, E.2
Martin-Caballero, J.3
Flores, J.M.4
Lee, H.W.5
Blasco, M.A.6
-
47
-
-
0029091386
-
Activation of telomerase in human lymphocytes and hematopoietic progenitor cells
-
7561072 1:CAS:528:DyaK2MXos1Kksrs%3D
-
Hiyama K, Hirai Y, Kyoizumi S, Akiyama M, Hiyama E, Piatyszek MA, Shay JW, Ishioka S and Yamakido M 1995 Activation of telomerase in human lymphocytes and hematopoietic progenitor cells. J. Immunol. 155 3711-3715
-
(1995)
J. Immunol.
, vol.155
, pp. 3711-3715
-
-
Hiyama, K.1
Hirai, Y.2
Kyoizumi, S.3
Akiyama, M.4
Hiyama, E.5
Piatyszek, M.A.6
Shay, J.W.7
Ishioka, S.8
Yamakido, M.9
-
49
-
-
0031922795
-
Telomeric length and telomerase activity vary with age in peripheral blood cells obtained from normal individuals
-
9600234 1:CAS:528:DyaK1cXit1aktLs%3D 10.1007/s004390050711
-
Iwama H, Ohyashiki K, Ohyashiki JH, Hayashi S, Yahata N, Ando K, Toyama K, Hoshika A, Takasaki M, Mori M and Shay JW 1998 Telomeric length and telomerase activity vary with age in peripheral blood cells obtained from normal individuals. Hum. Genet. 102 397-402
-
(1998)
Hum. Genet.
, vol.102
, pp. 397-402
-
-
Iwama, H.1
Ohyashiki, K.2
Ohyashiki, J.H.3
Hayashi, S.4
Yahata, N.5
Ando, K.6
Toyama, K.7
Hoshika, A.8
Takasaki, M.9
Mori, M.10
Shay, J.W.11
-
50
-
-
78650990326
-
Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice
-
21113150 1:CAS:528:DC%2BC3cXhsVOrsLnJ 10.1038/nature09603
-
Jaskelioff M, Muller FL, Paik JH, Thomas E, Jiang S, Adams AC, Sahin E, Kost-Alimova M, et al. 2011 Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice. Nature 469 102-106
-
(2011)
Nature
, vol.469
, pp. 102-106
-
-
Jaskelioff, M.1
Muller, F.L.2
Paik, J.H.3
Thomas, E.4
Jiang, S.5
Adams, A.C.6
Sahin, E.7
Kost-Alimova, M.8
-
51
-
-
34250017413
-
Telomere dysfunction induces environmental alterations limiting hematopoietic stem cell function and engraftment
-
17486088 1:CAS:528:DC%2BD2sXmtFeks7w%3D 10.1038/nm1578
-
Ju Z, Jiang H, Jaworski M, Rathinam C, Gompf A, Klein C, Trumpp A and Rudolph KL 2007 Telomere dysfunction induces environmental alterations limiting hematopoietic stem cell function and engraftment. Nat. Med. 13 742-747
-
(2007)
Nat. Med.
, vol.13
, pp. 742-747
-
-
Ju, Z.1
Jiang, H.2
Jaworski, M.3
Rathinam, C.4
Gompf, A.5
Klein, C.6
Trumpp, A.7
Rudolph, K.L.8
-
52
-
-
33744535197
-
Telomeres and telomerase in cancer stem cells
-
16644207 1:CAS:528:DC%2BD28XltlGqtrc%3D 10.1016/j.ejca.2006.01.040
-
Ju Z and Rudolph KL 2006 Telomeres and telomerase in cancer stem cells. Eur. J. Cancer 42 1197-1203
-
(2006)
Eur. J. Cancer
, vol.42
, pp. 1197-1203
-
-
Ju, Z.1
Rudolph, K.L.2
-
53
-
-
0030447934
-
Proliferative activity of the endometrium throughout the menstrual cycle in infertile women with and without endometriosis
-
8751731 1:STN:280:DyaK28zlt1Kiug%3D%3D
-
Jurgensen A, Mettler L, Volkov NI and Parwaresch R 1996 Proliferative activity of the endometrium throughout the menstrual cycle in infertile women with and without endometriosis. Fertil. Steril. 66 369-375
-
(1996)
Fertil. Steril.
, vol.66
, pp. 369-375
-
-
Jurgensen, A.1
Mettler, L.2
Volkov, N.I.3
Parwaresch, R.4
-
54
-
-
17644416412
-
The use of hTERT-immortalized cells in tissue engineering
-
19003242 10.1007/s10616-004-5124-2
-
Kassem M, Abdallah BM, Yu Z, Ditzel N and Burns JS 2004 The use of hTERT-immortalized cells in tissue engineering. Cytotechnology 45 39-46
-
(2004)
Cytotechnology
, vol.45
, pp. 39-46
-
-
Kassem, M.1
Abdallah, B.M.2
Yu, Z.3
Ditzel, N.4
Burns, J.S.5
-
55
-
-
67649224051
-
Deletion of Irs2 reduces amyloid deposition and rescues behavioural deficits in APP transgenic mice
-
19523444 1:CAS:528:DC%2BD1MXnvVansr4%3D 10.1016/j.bbrc.2009.06.032
-
Killick R, Scales G, Leroy K, Causevic M, Hooper C, Irvine EE, Choudhury AI, Drinkwater L, et al. 2009 Deletion of Irs2 reduces amyloid deposition and rescues behavioural deficits in APP transgenic mice. Biochem. Biophys. Res. Commun. 386 257-262
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.386
, pp. 257-262
-
-
Killick, R.1
Scales, G.2
Leroy, K.3
Causevic, M.4
Hooper, C.5
Irvine, E.E.6
Choudhury, A.I.7
Drinkwater, L.8
-
56
-
-
70350721794
-
Defining the pathogenic role of telomerase mutations in myelodysplastic syndrome and acute myeloid leukemia
-
19760749 1:CAS:528:DC%2BD1MXhsVyqs77P 10.1002/humu.21115
-
Kirwan M, Vulliamy T, Marrone A, Walne AJ, Beswick R, Hillmen P, Kelly R, Stewart A, et al. 2009 Defining the pathogenic role of telomerase mutations in myelodysplastic syndrome and acute myeloid leukemia. Hum. Mutat. 30 1567-1573
-
(2009)
Hum. Mutat.
, vol.30
, pp. 1567-1573
-
-
Kirwan, M.1
Vulliamy, T.2
Marrone, A.3
Walne, A.J.4
Beswick, R.5
Hillmen, P.6
Kelly, R.7
Stewart, A.8
-
58
-
-
0041968702
-
Integrating epithelial cancer, aging stroma and cellular senescence
-
12820530 1:STN:280:DC%2BD3s3ptlGnsw%3D%3D
-
Krtolica A and Campisi J 2003 Integrating epithelial cancer, aging stroma and cellular senescence. Adv. Gerontol. 11 109-116
-
(2003)
Adv. Gerontol.
, vol.11
, pp. 109-116
-
-
Krtolica, A.1
Campisi, J.2
-
59
-
-
0028091194
-
A cell initiating human acute myeloid leukaemia after transplantation into SCID mice
-
7509044 1:STN:280:DyaK2c7ltVKrsg%3D%3D 10.1038/367645a0
-
Lapidot T, Sirard C, Vormoor J, Murdoch B, Hoang T, Caceres-Cortes J, Minden M, Paterson B, Caligiuri MA and Dick JE 1994 A cell initiating human acute myeloid leukaemia after transplantation into SCID mice. Nature 367 645-648
-
(1994)
Nature
, vol.367
, pp. 645-648
-
-
Lapidot, T.1
Sirard, C.2
Vormoor, J.3
Murdoch, B.4
Hoang, T.5
Caceres-Cortes, J.6
Minden, M.7
Paterson, B.8
Caligiuri, M.A.9
Dick, J.E.10
-
60
-
-
0032499210
-
Essential role of mouse telomerase in highly proliferative organs
-
9560153 1:CAS:528:DyaK1cXis1Smu7o%3D 10.1038/33345
-
Lee HW, Blasco MA, Gottlieb GJ, Horner JW, Greider CW and DePinho RA 1998 Essential role of mouse telomerase in highly proliferative organs. Nature 392 569-574
-
(1998)
Nature
, vol.392
, pp. 569-574
-
-
Lee, H.W.1
Blasco, M.A.2
Gottlieb, G.J.3
Horner, J.W.4
Greider, C.W.5
Depinho, R.A.6
-
61
-
-
0032542364
-
Genetic instabilities in human cancers
-
9872311 1:CAS:528:DyaK1MXisVWqsQ%3D%3D 10.1038/25292
-
Lengauer C, Kinzler KW and Vogelstein B 1998 Genetic instabilities in human cancers. Nature 396 643-649
-
(1998)
Nature
, vol.396
, pp. 643-649
-
-
Lengauer, C.1
Kinzler, K.W.2
Vogelstein, B.3
-
62
-
-
1242272019
-
Telomerase deficiency impairs differentiation of mesenchymal stem cells
-
14980495 1:CAS:528:DC%2BD2cXhsV2gs74%3D 10.1016/j.yexcr.2003.10.031
-
Liu L, DiGirolamo CM, Navarro PA, Blasco MA and Keefe DL 2004 Telomerase deficiency impairs differentiation of mesenchymal stem cells. Exp. Cell Res. 294 1-8
-
(2004)
Exp. Cell Res.
, vol.294
, pp. 1-8
-
-
Liu, L.1
Digirolamo, C.M.2
Navarro, P.A.3
Blasco, M.A.4
Keefe, D.L.5
-
63
-
-
0035071327
-
Telomere erosion and senescence in human articular cartilage chondrocytes
-
11283188 1:STN:280:DC%2BD3M3js12hsQ%3D%3D 10.1093/gerona/56.4.B172
-
Martin JA and Buckwalter JA 2001 Telomere erosion and senescence in human articular cartilage chondrocytes. J. Gerontol. A Biol. Sci. Med. Sci. 56 B172-B179
-
(2001)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.56
-
-
Martin, J.A.1
Buckwalter, J.A.2
-
64
-
-
0032168370
-
Expression of mouse telomerase catalytic subunit in embryos and adult tissues
-
9724727 1:CAS:528:DyaK1cXlvFWgtrc%3D 10.1073/pnas.95.18.10471
-
Martin-Rivera L, Herrera E, Albar JP and Blasco MA 1998 Expression of mouse telomerase catalytic subunit in embryos and adult tissues. Proc. Natl. Acad. Sci. U. S. A 95 10471-10476
-
(1998)
Proc. Natl. Acad. Sci. U. S. A
, vol.95
, pp. 10471-10476
-
-
Martin-Rivera, L.1
Herrera, E.2
Albar, J.P.3
Blasco, M.A.4
-
65
-
-
20944439487
-
Fetal bone cells for tissue engineering
-
15589213 1:CAS:528:DC%2BD2cXhtVOntb7K 10.1016/j.bone.2004.07.001
-
Montjovent MO, Burri N, Mark S, Federici E, Scaletta C, Zambelli PY, Hohlfeld P, Leyvraz PF, Applegate LL and Pioletti DP 2004 Fetal bone cells for tissue engineering. Bone 35 1323-1333
-
(2004)
Bone
, vol.35
, pp. 1323-1333
-
-
Montjovent, M.O.1
Burri, N.2
Mark, S.3
Federici, E.4
Scaletta, C.5
Zambelli, P.Y.6
Hohlfeld, P.7
Leyvraz, P.F.8
Applegate, L.L.9
Pioletti, D.P.10
-
66
-
-
0030248792
-
Telomerase activity in hematopoietic cells is associated with self-renewal potential
-
8808676 1:CAS:528:DyaK28XmtVGmt7s%3D 10.1016/S1074-7613(00)80316-7
-
Morrison SJ, Prowse KR, Ho P and Weissman IL 1996 Telomerase activity in hematopoietic cells is associated with self-renewal potential. Immunity 5 207-216
-
(1996)
Immunity
, vol.5
, pp. 207-216
-
-
Morrison, S.J.1
Prowse, K.R.2
Ho, P.3
Weissman, I.L.4
-
67
-
-
0036845282
-
Replicative aging of human articular chondrocytes during ex vivo expansion
-
12428231 1:CAS:528:DC%2BD38XptlSksro%3D 10.1002/art.10626
-
Parsch D, Brummendorf TH, Richter W and Fellenberg J 2002 Replicative aging of human articular chondrocytes during ex vivo expansion. Arthritis Rheum. 46 2911-2916
-
(2002)
Arthritis Rheum.
, vol.46
, pp. 2911-2916
-
-
Parsch, D.1
Brummendorf, T.H.2
Richter, W.3
Fellenberg, J.4
-
68
-
-
0842330317
-
Telomere length and telomerase activity during expansion and differentiation of human mesenchymal stem cells and chondrocytes
-
14647922 1:CAS:528:DC%2BD2cXhs1Gntg%3D%3D 10.1007/s00109-003-0506-z
-
Parsch D, Fellenberg J, Brummendorf TH, Eschlbeck AM and Richter W 2004 Telomere length and telomerase activity during expansion and differentiation of human mesenchymal stem cells and chondrocytes. J. Mol. Med. 82 49-55
-
(2004)
J. Mol. Med.
, vol.82
, pp. 49-55
-
-
Parsch, D.1
Fellenberg, J.2
Brummendorf, T.H.3
Eschlbeck, A.M.4
Richter, W.5
-
69
-
-
38349192848
-
Defects in telomere maintenance molecules impair osteoblast differentiation and promote osteoporosis
-
18028256 1:CAS:528:DC%2BD1cXit1Ons7w%3D 10.1111/j.1474-9726.2007.00350.x
-
Pignolo RJ, Suda RK, McMillan EA, Shen J, Lee SH, Choi Y, Wright AC and Johnson FB 2008 Defects in telomere maintenance molecules impair osteoblast differentiation and promote osteoporosis. Aging Cell 7 23-31
-
(2008)
Aging Cell
, vol.7
, pp. 23-31
-
-
Pignolo, R.J.1
Suda, R.K.2
McMillan, E.A.3
Shen, J.4
Lee, S.H.5
Choi, Y.6
Wright, A.C.7
Johnson, F.B.8
-
70
-
-
3042780966
-
Hepatocellular telomere shortening correlates with chromosomal instability and the development of human hepatoma
-
15239089 1:CAS:528:DC%2BD2cXmtlSgtb8%3D 10.1002/hep.20271
-
Plentz RR, Caselitz M, Bleck JS, Gebel M, Flemming P, Kubicka S, Manns MP and Rudolph KL 2004 Hepatocellular telomere shortening correlates with chromosomal instability and the development of human hepatoma. Hepatology 40 80-86
-
(2004)
Hepatology
, vol.40
, pp. 80-86
-
-
Plentz, R.R.1
Caselitz, M.2
Bleck, J.S.3
Gebel, M.4
Flemming, P.5
Kubicka, S.6
Manns, M.P.7
Rudolph, K.L.8
-
71
-
-
0042887525
-
Telomere shortening of epithelial cells characterises the adenoma-carcinoma transition of human colorectal cancer
-
12912862 1:STN:280:DC%2BD3sznsleqtw%3D%3D 10.1136/gut.52.9.1304
-
Plentz RR, Wiemann SU, Flemming P, Meier PN, Kubicka S, Kreipe H, Manns MP and Rudolph KL 2003 Telomere shortening of epithelial cells characterises the adenoma-carcinoma transition of human colorectal cancer. Gut 52 1304-1307
-
(2003)
Gut
, vol.52
, pp. 1304-1307
-
-
Plentz, R.R.1
Wiemann, S.U.2
Flemming, P.3
Meier, P.N.4
Kubicka, S.5
Kreipe, H.6
Manns, M.P.7
Rudolph, K.L.8
-
72
-
-
21344434558
-
The impact of telomere erosion on memory CD8+ T cells in patients with X-linked lymphoproliferative syndrome
-
15992610 1:CAS:528:DC%2BD2MXlvVWnu7c%3D 10.1016/j.mad.2005.03.006
-
Plunkett FJ, Franzese O, Belaramani LL, Fletcher JM, Gilmour KC, Sharifi R, Khan N, Hislop AD, et al. 2005 The impact of telomere erosion on memory CD8+ T cells in patients with X-linked lymphoproliferative syndrome. Mech. Ageing Dev. 126 855-865
-
(2005)
Mech. Ageing Dev.
, vol.126
, pp. 855-865
-
-
Plunkett, F.J.1
Franzese, O.2
Belaramani, L.L.3
Fletcher, J.M.4
Gilmour, K.C.5
Sharifi, R.6
Khan, N.7
Hislop, A.D.8
-
73
-
-
33745614062
-
Stem cells, ageing and the quest for immortality
-
16810243 1:CAS:528:DC%2BD28Xmtlahsrc%3D 10.1038/nature04958
-
Rando TA 2006 Stem cells, ageing and the quest for immortality. Nature 441 1080-1086
-
(2006)
Nature
, vol.441
, pp. 1080-1086
-
-
Rando, T.A.1
-
74
-
-
34250370523
-
Ectopic telomerase expression inhibits neuronal differentiation of NT2 neural progenitor cells
-
17566647 1:CAS:528:DC%2BD2sXmsFCnsbY%3D 10.1016/j.neulet.2007.03.079
-
Richardson RM, Nguyen B, Holt SE, Broaddus WC and Fillmore HL 2007 Ectopic telomerase expression inhibits neuronal differentiation of NT2 neural progenitor cells. Neurosci. Lett. 421 168-172
-
(2007)
Neurosci. Lett.
, vol.421
, pp. 168-172
-
-
Richardson, R.M.1
Nguyen, B.2
Holt, S.E.3
Broaddus, W.C.4
Fillmore, H.L.5
-
75
-
-
79959699254
-
Telomere shortening reduces Alzheimer's disease amyloid pathology in mice
-
21672962 10.1093/brain/awr133
-
Rolyan H, Scheffold A, Heinrich A, Begus-Nahrmann Y, Langkopf BH, Holter SM, Vogt-Weisenhorn DM, Liss B, et al. 2011 Telomere shortening reduces Alzheimer's disease amyloid pathology in mice. Brain 134 2044-2056
-
(2011)
Brain
, vol.134
, pp. 2044-2056
-
-
Rolyan, H.1
Scheffold, A.2
Heinrich, A.3
Begus-Nahrmann, Y.4
Langkopf, B.H.5
Holter, S.M.6
Vogt-Weisenhorn, D.M.7
Liss, B.8
-
76
-
-
39149086121
-
Stems cells and the pathways to aging and cancer
-
18295583 1:CAS:528:DC%2BD1cXivVagt74%3D 10.1016/j.cell.2008.01.036
-
Rossi DJ, Jamieson CH and Weissman IL 2008 Stems cells and the pathways to aging and cancer. Cell 132 681-696
-
(2008)
Cell
, vol.132
, pp. 681-696
-
-
Rossi, D.J.1
Jamieson, C.H.2
Weissman, I.L.3
-
77
-
-
17944401846
-
Telomerase is limiting the growth of acute myeloid leukemia cells
-
14562114 1:CAS:528:DC%2BD3sXps12itbY%3D 10.1038/sj.leu.2403177
-
Roth A, Vercauteren S, Sutherland HJ and Lansdorp PM 2003 Telomerase is limiting the growth of acute myeloid leukemia cells. Leukemia 17 2410-2417
-
(2003)
Leukemia
, vol.17
, pp. 2410-2417
-
-
Roth, A.1
Vercauteren, S.2
Sutherland, H.J.3
Lansdorp, P.M.4
-
78
-
-
0033525558
-
Longevity, stress response, and cancer in aging telomerase-deficient mice
-
10089885 1:CAS:528:DyaK1MXitVChs7w%3D 10.1016/S0092-8674(00)80580-2
-
Rudolph KL, Chang S, Lee HW, Blasco M, Gottlieb GJ, Greider C and DePinho RA 1999 Longevity, stress response, and cancer in aging telomerase-deficient mice. Cell 96 701-712
-
(1999)
Cell
, vol.96
, pp. 701-712
-
-
Rudolph, K.L.1
Chang, S.2
Lee, H.W.3
Blasco, M.4
Gottlieb, G.J.5
Greider, C.6
Depinho, R.A.7
-
79
-
-
0034978564
-
Telomere dysfunction and evolution of intestinal carcinoma in mice and humans
-
11381263 1:CAS:528:DC%2BD3MXktFOrtLk%3D 10.1038/88871
-
Rudolph KL, Millard M, Bosenberg MW and DePinho RA 2001 Telomere dysfunction and evolution of intestinal carcinoma in mice and humans. Nat. Genet. 28 155-159
-
(2001)
Nat. Genet.
, vol.28
, pp. 155-159
-
-
Rudolph, K.L.1
Millard, M.2
Bosenberg, M.W.3
Depinho, R.A.4
-
80
-
-
0345643319
-
Telomere fluorescence measurements in granulocytes and T lymphocyte subsets point to a high turnover of hematopoietic stem cells and memory T cells in early childhood
-
10432279 1:CAS:528:DyaK1MXkslSjtbs%3D 10.1084/jem.190.2.157
-
Rufer N, Brummendorf TH, Kolvraa S, Bischoff C, Christensen K, Wadsworth L, Schulzer M and Lansdorp PM 1999 Telomere fluorescence measurements in granulocytes and T lymphocyte subsets point to a high turnover of hematopoietic stem cells and memory T cells in early childhood. J. Exp. Med. 190 157-167
-
(1999)
J. Exp. Med.
, vol.190
, pp. 157-167
-
-
Rufer, N.1
Brummendorf, T.H.2
Kolvraa, S.3
Bischoff, C.4
Christensen, K.5
Wadsworth, L.6
Schulzer, M.7
Lansdorp, P.M.8
-
81
-
-
79959509852
-
Telomerase-deficient mice exhibit bone loss due to defects in osteoblasts and increased osteoclastogenesis by inflammatory microenvironment
-
Saeed H, Abdallah BM, Ditzel N, Catala-Lehnen P, Qiu W, Amling M and Kassem M 2011 Telomerase-deficient mice exhibit bone loss due to defects in osteoblasts and increased osteoclastogenesis by inflammatory microenvironment. J. Bone Miner. Res
-
(2011)
J. Bone Miner. Res
-
-
Saeed, H.1
Abdallah, B.M.2
Ditzel, N.3
Catala-Lehnen, P.4
Qiu, W.5
Amling, M.6
Kassem, M.7
-
82
-
-
77950265945
-
Linking functional decline of telomeres, mitochondria and stem cells during ageing
-
20336134 1:CAS:528:DC%2BC3cXjvVGlsbo%3D 10.1038/nature08982
-
Sahin E and DePinho RA 2010 Linking functional decline of telomeres, mitochondria and stem cells during ageing. Nature 464 520-528
-
(2010)
Nature
, vol.464
, pp. 520-528
-
-
Sahin, E.1
Depinho, R.A.2
-
83
-
-
23944516520
-
Conditional telomerase induction causes proliferation of hair follicle stem cells
-
16107853 1:CAS:528:DC%2BD2MXotFensbg%3D 10.1038/nature03836
-
Sarin KY, Cheung P, Gilison D, Lee E, Tennen RI, Wang E, Artandi MK, Oro AE and Artandi SE 2005 Conditional telomerase induction causes proliferation of hair follicle stem cells. Nature 436 1048-1052
-
(2005)
Nature
, vol.436
, pp. 1048-1052
-
-
Sarin, K.Y.1
Cheung, P.2
Gilison, D.3
Lee, E.4
Tennen, R.I.5
Wang, E.6
Artandi, M.K.7
Oro, A.E.8
Artandi, S.E.9
-
84
-
-
4043124073
-
Telomeres and telomerase: A dual role in hepatocarcinogenesis
-
15368430 1:CAS:528:DC%2BD2cXnsFygtbw%3D 10.1002/hep.20308
-
Satyanarayana A, Manns MP and Rudolph KL 2004 Telomeres and telomerase: a dual role in hepatocarcinogenesis. Hepatology 40 276-283
-
(2004)
Hepatology
, vol.40
, pp. 276-283
-
-
Satyanarayana, A.1
Manns, M.P.2
Rudolph, K.L.3
-
85
-
-
13644249950
-
Telomerase activity and telomere length of human mesenchymal stem cells. Changes during osteogenic differentiation
-
15549250 1:STN:280:DC%2BD2cngsVGnsA%3D%3D 10.1007/s00132-004-0739-8
-
Schieker M, Gulkan H, Austrup B, Neth P and Mutschler W 2004 Telomerase activity and telomere length of human mesenchymal stem cells. Changes during osteogenic differentiation. Orthopade 33 1373-1377
-
(2004)
Orthopade
, vol.33
, pp. 1373-1377
-
-
Schieker, M.1
Gulkan, H.2
Austrup, B.3
Neth, P.4
Mutschler, W.5
-
86
-
-
13344249773
-
Differentiation of immortal cells inhibits telomerase activity
-
8618897 1:CAS:528:DyaK28Xhtl2mtA%3D%3D 10.1073/pnas.92.26.12343
-
Sharma HW, Sokoloski JA, Perez JR, Maltese JY, Sartorelli AC, Stein CA, Nichols G, Khaled Z, Telang NT and Narayanan R 1995 Differentiation of immortal cells inhibits telomerase activity. Proc. Natl. Acad. Sci. USA 92 12343-12346
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 12343-12346
-
-
Sharma, H.W.1
Sokoloski, J.A.2
Perez, J.R.3
Maltese, J.Y.4
Sartorelli, A.C.5
Stein, C.A.6
Nichols, G.7
Khaled, Z.8
Telang, N.T.9
Narayanan, R.10
-
87
-
-
85047689866
-
Telomeres, stem cells, senescence, and cancer
-
14722605 1:CAS:528:DC%2BD2cXmsVykug%3D%3D
-
Sharpless NE and DePinho RA 2004 Telomeres, stem cells, senescence, and cancer. J. Clin. Invest. 113 160-168
-
(2004)
J. Clin. Invest.
, vol.113
, pp. 160-168
-
-
Sharpless, N.E.1
Depinho, R.A.2
-
88
-
-
34548153747
-
How stem cells age and why this makes us grow old
-
17717515 1:CAS:528:DC%2BD2sXpsVartb0%3D 10.1038/nrm2241
-
Sharpless NE and DePinho RA 2007 How stem cells age and why this makes us grow old. Nat. Rev. Mol. Cell Biol. 8 703-713
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 703-713
-
-
Sharpless, N.E.1
Depinho, R.A.2
-
89
-
-
0035984714
-
Telomerase expression extends the proliferative life-span and maintains the osteogenic potential of human bone marrow stromal cells
-
12042863 1:CAS:528:DC%2BD38XktFOiu7s%3D 10.1038/nbt0602-592
-
Simonsen JL, Rosada C, Serakinci N, Justesen J, Stenderup K, Rattan SI, Jensen TG and Kassem M 2002 Telomerase expression extends the proliferative life-span and maintains the osteogenic potential of human bone marrow stromal cells. Nat. Biotechnol. 20 592-596
-
(2002)
Nat. Biotechnol.
, vol.20
, pp. 592-596
-
-
Simonsen, J.L.1
Rosada, C.2
Serakinci, N.3
Justesen, J.4
Stenderup, K.5
Rattan, S.I.6
Jensen, T.G.7
Kassem, M.8
-
90
-
-
0012950854
-
Lineage-specific telomere shortening and unaltered capacity for telomerase expression in human T and B lymphocytes with age
-
10903716 1:CAS:528:DC%2BD3cXmtFykt70%3D
-
Son NH, Murray S, Yanovski J, Hodes RJ and Weng N 2000 Lineage-specific telomere shortening and unaltered capacity for telomerase expression in human T and B lymphocytes with age. J. Immunol. 165 1191-1196
-
(2000)
J. Immunol.
, vol.165
, pp. 1191-1196
-
-
Son, N.H.1
Murray, S.2
Yanovski, J.3
Hodes, R.J.4
Weng, N.5
-
91
-
-
77949904634
-
Alterations of the systemic environment are the primary cause of impaired B and T lymphopoiesis in telomere-dysfunctional mice
-
19965646 10.1182/blood-2009-08-237230
-
Song Z, Wang J, Guachalla LM, Terszowski G, Rodewald HR, Ju Z and Rudolph KL 2010 Alterations of the systemic environment are the primary cause of impaired B and T lymphopoiesis in telomere-dysfunctional mice. Blood 115 1481-1489
-
(2010)
Blood
, vol.115
, pp. 1481-1489
-
-
Song, Z.1
Wang, J.2
Guachalla, L.M.3
Terszowski, G.4
Rodewald, H.R.5
Ju, Z.6
Rudolph, K.L.7
-
92
-
-
0347627149
-
Aging is associated with decreased maximal life span and accelerated senescence of bone marrow stromal cells
-
14678851 10.1016/j.bone.2003.07.005
-
Stenderup K, Justesen J, Clausen C and Kassem M 2003 Aging is associated with decreased maximal life span and accelerated senescence of bone marrow stromal cells. Bone 33 919-926
-
(2003)
Bone
, vol.33
, pp. 919-926
-
-
Stenderup, K.1
Justesen, J.2
Clausen, C.3
Kassem, M.4
-
93
-
-
18044370239
-
Telomere maintenance and tumorigenesis: An 'ALT'ernative road
-
15974880 1:CAS:528:DC%2BD2MXjslaisro%3D 10.2174/1566524053586653
-
Stewart SA 2005 Telomere maintenance and tumorigenesis: an 'ALT'ernative road. Curr. Mol. Med. 5 253-257
-
(2005)
Curr. Mol. Med.
, vol.5
, pp. 253-257
-
-
Stewart, S.A.1
-
94
-
-
0035686807
-
Neural stem cells lose telomerase activity upon differentiating into astrocytes
-
19003324 1:CAS:528:DC%2BD38XovV2rsw%3D%3D 10.1023/A:1014016315003
-
T Miura, Y Katakura, K Yamamoto, N Uehara, T Tsuchiya, E H Kim and S Shirahata 2001 Neural stem cells lose telomerase activity upon differentiating into astrocytes. Cytotechnology 36 137-144
-
(2001)
Cytotechnology
, vol.36
, pp. 137-144
-
-
Miura, T.1
Katakura, Y.2
Yamamoto, K.3
Uehara, N.4
Tsuchiya, T.5
Kim, E.H.6
Shirahata, S.7
-
95
-
-
0034884594
-
Telomerase activity and patient survival after surgery for gastric and oesophageal cancer
-
11507353 1:CAS:528:DC%2BD3MXms1ShtLo%3D 10.1097/00042737-200108000-00005
-
Usselmann B, Newbold M, Morris AG and Nwokolo CU 2001 Telomerase activity and patient survival after surgery for gastric and oesophageal cancer. Eur. J. Gastroenterol. Hepatol. 13 903-908
-
(2001)
Eur. J. Gastroenterol. Hepatol.
, vol.13
, pp. 903-908
-
-
Usselmann, B.1
Newbold, M.2
Morris, A.G.3
Nwokolo, C.U.4
-
96
-
-
0028077099
-
Evidence for a mitotic clock in human hematopoietic stem cells: Loss of telomeric DNA with age
-
7937905 1:CAS:528:DyaK2cXmsFahurk%3D 10.1073/pnas.91.21.9857
-
Vaziri H, Dragowska W, Allsopp RC, Thomas TE, Harley CB and Lansdorp PM 1994 Evidence for a mitotic clock in human hematopoietic stem cells: loss of telomeric DNA with age. Proc. Natl. Acad. Sci. USA 91 9857-9860
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 9857-9860
-
-
Vaziri, H.1
Dragowska, W.2
Allsopp, R.C.3
Thomas, T.E.4
Harley, C.B.5
Lansdorp, P.M.6
-
97
-
-
0027486732
-
Loss of telomeric DNA during aging of normal and trisomy 21 human lymphocytes
-
8460632 1:CAS:528:DyaK2cXhs1Sks7c%3D
-
Vaziri H, Schachter F, Uchida I, Wei L, Zhu X, Effros R, Cohen D and Harley CB 1993 Loss of telomeric DNA during aging of normal and trisomy 21 human lymphocytes. Am. J. Hum. Genet. 52 661-667
-
(1993)
Am. J. Hum. Genet.
, vol.52
, pp. 661-667
-
-
Vaziri, H.1
Schachter, F.2
Uchida, I.3
Wei, L.4
Zhu, X.5
Effros, R.6
Cohen, D.7
Harley, C.B.8
-
98
-
-
0034992999
-
Stress, DNA damage and ageing - An integrative approach
-
von ZT, Burkle A and Kirkwood TB 2001 Stress, DNA damage and ageing - an integrative approach. Exp. Gerontol. 36 1049-1062
-
(2001)
Exp. Gerontol.
, vol.36
, pp. 1049-1062
-
-
Von Zt1
Burkle, A.2
Kirkwood, T.B.3
-
99
-
-
0037157582
-
Association between aplastic anaemia and mutations in telomerase RNA
-
12090986 1:CAS:528:DC%2BD38XkslGhtrk%3D 10.1016/S0140-6736(02)09087-6
-
Vulliamy T, Marrone A, Dokal I and Mason PJ 2002 Association between aplastic anaemia and mutations in telomerase RNA. Lancet 359 2168-2170
-
(2002)
Lancet
, vol.359
, pp. 2168-2170
-
-
Vulliamy, T.1
Marrone, A.2
Dokal, I.3
Mason, P.J.4
-
100
-
-
2442617343
-
Disease anticipation is associated with progressive telomere shortening in families with dyskeratosis congenita due to mutations in TERC
-
15098033 1:CAS:528:DC%2BD2cXjsFSnt70%3D 10.1038/ng1346
-
Vulliamy T, Marrone A, Szydlo R, Walne A, Mason PJ and Dokal I 2004 Disease anticipation is associated with progressive telomere shortening in families with dyskeratosis congenita due to mutations in TERC. Nat. Genet. 36 447-449
-
(2004)
Nat. Genet.
, vol.36
, pp. 447-449
-
-
Vulliamy, T.1
Marrone, A.2
Szydlo, R.3
Walne, A.4
Mason, P.J.5
Dokal, I.6
-
101
-
-
4043105534
-
Ex vivo homeostatic proliferation of CD4+ T cells in rheumatoid arthritis is dysregulated and driven by membrane-anchored TNF alpha
-
15295001 1:CAS:528:DC%2BD2cXmt1Oktrg%3D
-
Wagner U, Pierer M, Wahle M, Moritz F, Kaltenhauser S and Hantzschel H 2004 Ex vivo homeostatic proliferation of CD4+ T cells in rheumatoid arthritis is dysregulated and driven by membrane-anchored TNF alpha. J. Immunol. 173 2825-2833
-
(2004)
J. Immunol.
, vol.173
, pp. 2825-2833
-
-
Wagner, U.1
Pierer, M.2
Wahle, M.3
Moritz, F.4
Kaltenhauser, S.5
Hantzschel, H.6
-
102
-
-
0034614576
-
Stem cells: Units of development, units of regeneration, and units in evolution
-
10647940 1:CAS:528:DC%2BD3cXks1Cqsw%3D%3D 10.1016/S0092-8674(00)81692-X
-
Weissman IL 2000 Stem cells: units of development, units of regeneration, and units in evolution. Cell 100 157-168
-
(2000)
Cell
, vol.100
, pp. 157-168
-
-
Weissman, I.L.1
-
103
-
-
0028850465
-
Human naive and memory T lymphocytes differ in telomeric length and replicative potential
-
7479943 1:CAS:528:DyaK2MXps1alsLs%3D 10.1073/pnas.92.24.11091
-
Weng NP, Levine BL, June CH and Hodes RJ 1995 Human naive and memory T lymphocytes differ in telomeric length and replicative potential. Proc. Natl. Acad. Sci. USA 92 11091-11094
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 11091-11094
-
-
Weng, N.P.1
Levine, B.L.2
June, C.H.3
Hodes, R.J.4
-
104
-
-
0029894199
-
Regulated expression of telomerase activity in human T lymphocyte development and activation
-
8676067 1:CAS:528:DyaK28XjslaisrY%3D 10.1084/jem.183.6.2471
-
Weng NP, Levine BL, June CH and Hodes RJ 1996 Regulated expression of telomerase activity in human T lymphocyte development and activation. J. Exp. Med. 183 2471-2479
-
(1996)
J. Exp. Med.
, vol.183
, pp. 2471-2479
-
-
Weng, N.P.1
Levine, B.L.2
June, C.H.3
Hodes, R.J.4
-
105
-
-
0026680249
-
The two-stage mechanism controlling cellular senescence and immortalization
-
1333985 1:CAS:528:DyaK38XmtlSlsbk%3D 10.1016/0531-5565(92)90069-C
-
Wright WE and Shay JW 1992 The two-stage mechanism controlling cellular senescence and immortalization. Exp. Gerontol. 27 383-389
-
(1992)
Exp. Gerontol.
, vol.27
, pp. 383-389
-
-
Wright, W.E.1
Shay, J.W.2
-
106
-
-
0034667816
-
Telomerase activity is increased and telomere length shortened in T cells from blood of patients with atopic dermatitis and psoriasis
-
11035119 1:CAS:528:DC%2BD3cXnslWnsbY%3D
-
Wu K, Higashi N, Hansen ER, Lund M, Bang K and Thestrup-Pedersen K 2000 Telomerase activity is increased and telomere length shortened in T cells from blood of patients with atopic dermatitis and psoriasis. J. Immunol. 165 4742-4747
-
(2000)
J. Immunol.
, vol.165
, pp. 4742-4747
-
-
Wu, K.1
Higashi, N.2
Hansen, E.R.3
Lund, M.4
Bang, K.5
Thestrup-Pedersen, K.6
-
107
-
-
0034925471
-
Reconstituting telomerase activity using the telomerase catalytic subunit prevents the telomere shorting and replicative senescence in human osteoblasts
-
11499868 1:CAS:528:DC%2BD3MXmtVOhtbs%3D 10.1359/jbmr.2001.16.8.1453
-
Yudoh K, Matsuno H, Nakazawa F, Katayama R and Kimura T 2001 Reconstituting telomerase activity using the telomerase catalytic subunit prevents the telomere shorting and replicative senescence in human osteoblasts. J. Bone Miner. Res. 16 1453-1464
-
(2001)
J. Bone Miner. Res.
, vol.16
, pp. 1453-1464
-
-
Yudoh, K.1
Matsuno, H.2
Nakazawa, F.3
Katayama, R.4
Kimura, T.5
-
108
-
-
84859762548
-
Mechanisms underlying the osteo- and adipo-differentiation of human mesenchymal stem cells
-
Zhang Y, Khan D, Delling J and Tobiasch E 2012 Mechanisms underlying the osteo- and adipo-differentiation of human mesenchymal stem cells. Sci. World J. 2012 793823
-
(2012)
Sci. World J.
, vol.2012
, pp. 793823
-
-
Zhang, Y.1
Khan, D.2
Delling, J.3
Tobiasch, E.4
-
109
-
-
41149117381
-
Cell cycle dependent telomere regulation by telomerase in human bone marrow mesenchymal stem cells
-
18339310 1:CAS:528:DC%2BD1cXksVejurw%3D 10.1016/j.bbrc.2008.03.011
-
Zhao YM, Li JY, Lan JP, Lai XY, Luo Y, Sun J, Yu J, Zhu YY, Zeng FF, Zhou Q and Huang H 2008 Cell cycle dependent telomere regulation by telomerase in human bone marrow mesenchymal stem cells. Biochem. Biophys. Res. Commun. 369 1114-1119
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.369
, pp. 1114-1119
-
-
Zhao, Y.M.1
Li, J.Y.2
Lan, J.P.3
Lai, X.Y.4
Luo, Y.5
Sun, J.6
Yu, J.7
Zhu, Y.Y.8
Zeng, F.F.9
Zhou, Q.10
Huang, H.11
-
110
-
-
0038717085
-
Lack of telomerase activity in human mesenchymal stem cells
-
12764382 1:CAS:528:DC%2BD3sXjvFKjtL4%3D 10.1038/sj.leu.2402962
-
Zimmermann S, Voss M, Kaiser S, Kapp U, Waller CF and Martens UM 2003 Lack of telomerase activity in human mesenchymal stem cells. Leukemia 17 1146-1149
-
(2003)
Leukemia
, vol.17
, pp. 1146-1149
-
-
Zimmermann, S.1
Voss, M.2
Kaiser, S.3
Kapp, U.4
Waller, C.F.5
Martens, U.M.6
|