Impact of telomerase ablation on organismal viability, aging, and tumorigenesis in mice lacking the DNA repair proteins PARP-1, Ku86, or DNA-PKcs

Journal of Cell Biology

Volumn 167, Issue 4, 2004, Pages 627-638

  Espejel, Silvia ^a   Klatt, Peter ^a   Ménissier De Murcia, Josiane ^b   Martín Caballero, Juan ^a   Flores, Juana M ^c   Taccioli, Guillermo ^d   De Murcia, Gilbert ^b   Blasco, María A ^a  

^a Structural Biology and Biocomputing Programme   (Spain)

^b CNRS   (France)

^c UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^d BOSTON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYRIBONUCLEOPROTEIN; KU ANTIGEN; POLY(ADENOSINE DIPHOSPHATE RIBOSE); TELOMERASE;

AGING; ANIMAL TISSUE; ARTICLE; CANCER; CARCINOGENESIS; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DNA REPAIR; EMBRYO; ENZYME DEFICIENCY; INCIDENCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TELOMERE;

AGING, PREMATURE; ANIMALS; ANTIGENS, NUCLEAR; CELL DIVISION; CELL TRANSFORMATION, NEOPLASTIC; CHROMOSOMAL INSTABILITY; DNA REPAIR; DNA-ACTIVATED PROTEIN KINASE; DNA-BINDING PROTEINS; FEMALE; LONGEVITY; MALE; MICE; MICE, KNOCKOUT; NEOPLASMS; POLY(ADP-RIBOSE) POLYMERASES; PROTEIN-SERINE-THREONINE KINASES; TELOMERASE; TELOMERE;

ANIMALIA;

EID: 9444243224     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200407178     Document Type: Article

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