메뉴 건너뛰기




Volumn 7, Issue 1, 2008, Pages 23-31

Defects in telomere maintenance molecules impair osteoblast differentiation and promote osteoporosis

Author keywords

Aging; Dyskeratosis congenita; Osteoblast differentiation; Osteoporosis; Telomerase; Werner syndrome

Indexed keywords

TELOMERASE; WERNER SYNDROME PROTEIN;

EID: 38349192848     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/j.1474-9726.2007.00350.x     Document Type: Article
Times cited : (119)

References (32)
  • 2
    • 0037308404 scopus 로고    scopus 로고
    • Association between telomere length in blood and mortality in people aged 60 years or older
    • Cawthon RM, Smith KR, O'Brien E, Sivatchenko A, Kerber RA (2003) Association between telomere length in blood and mortality in people aged 60 years or older. Lancet 361, 393-395.
    • (2003) Lancet , vol.361 , pp. 393-395
    • Cawthon, R.M.1    Smith, K.R.2    O'Brien, E.3    Sivatchenko, A.4    Kerber, R.A.5
  • 3
    • 0036184457 scopus 로고    scopus 로고
    • Age-related bone loss: Old bone, new facts
    • Chan GK, Duque G (2002) Age-related bone loss: Old bone, new facts. Gerontology 48, 62-71.
    • (2002) Gerontology , vol.48 , pp. 62-71
    • Chan, G.K.1    Duque, G.2
  • 5
    • 10344256183 scopus 로고    scopus 로고
    • Defective telomere lagging strand synthesis in cells lacking WRN helicase activity
    • Crabbe L, Verdun RE, Haggblom CI, Karlseder J (2004) Defective telomere lagging strand synthesis in cells lacking WRN helicase activity. Science 306, 1951-1953.
    • (2004) Science , vol.306 , pp. 1951-1953
    • Crabbe, L.1    Verdun, R.E.2    Haggblom, C.I.3    Karlseder, J.4
  • 7
    • 0038424780 scopus 로고    scopus 로고
    • Telomerase accelerates osteogenesis of bone marrow stromal stem cells by upregulation of CBFA1, osterix, and osteocalcin
    • Gronthos S, Chen S, Wang CY, Robey PG, Shi S (2003) Telomerase accelerates osteogenesis of bone marrow stromal stem cells by upregulation of CBFA1, osterix, and osteocalcin. J. Bone Miner. Res. 18, 716-722.
    • (2003) J. Bone Miner. Res. , vol.18 , pp. 716-722
    • Gronthos, S.1    Chen, S.2    Wang, C.Y.3    Robey, P.G.4    Shi, S.5
  • 9
    • 0033153424 scopus 로고    scopus 로고
    • Disease states associated with telomerase deficiency appear earlier in mice with short telomeres
    • Herrera E, Samper E, Martin-Caballero J, Flores JM, Lee HW, Blasco MA (1999) Disease states associated with telomerase deficiency appear earlier in mice with short telomeres. EMBO J. 18, 2950-2960.
    • (1999) EMBO J. , vol.18 , pp. 2950-2960
    • Herrera, E.1    Samper, E.2    Martin-Caballero, J.3    Flores, J.M.4    Lee, H.W.5    Blasco, M.A.6
  • 11
    • 0035865143 scopus 로고    scopus 로고
    • The Saccharomyces cerevisiae WRN homolog Sgs1p participates in telomere maintenance in cells lacking telomerase
    • Johnson FB, Marciniak RA, McVey M, Stewart SA, Hahn WC, Guarente L (2001) The Saccharomyces cerevisiae WRN homolog Sgs1p participates in telomere maintenance in cells lacking telomerase. EMBO J. 20, 905-913.
    • (2001) EMBO J. , vol.20 , pp. 905-913
    • Johnson, F.B.1    Marciniak, R.A.2    McVey, M.3    Stewart, S.A.4    Hahn, W.C.5    Guarente, L.6
  • 12
    • 0031441654 scopus 로고    scopus 로고
    • Demonstration of cellular aging and senescence in serially passaged long-term cultures of human trabecular osteoblasts
    • Kassem M, Ankersen L, Eriksen EF, Clark BF, Rattan SI (1997) Demonstration of cellular aging and senescence in serially passaged long-term cultures of human trabecular osteoblasts. Osteoporos Int. 7, 514-524.
    • (1997) Osteoporos Int. , vol.7 , pp. 514-524
    • Kassem, M.1    Ankersen, L.2    Eriksen, E.F.3    Clark, B.F.4    Rattan, S.I.5
  • 14
    • 0031194017 scopus 로고    scopus 로고
    • Characterization of human bone marrow stromal cells with respect to osteoblastic differentiation
    • Majors AK, Boehm CA, Nitto H, Midura RJ, Muschler GF (1997) Characterization of human bone marrow stromal cells with respect to osteoblastic differentiation. J. Orthop. Res. 15, 546-557.
    • (1997) J. Orthop. Res. , vol.15 , pp. 546-557
    • Majors, A.K.1    Boehm, C.A.2    Nitto, H.3    Midura, R.J.4    Muschler, G.F.5
  • 16
    • 0034894689 scopus 로고    scopus 로고
    • Changes in osteocalcin response to 1,25-dihydroxyvitamin D(3) stimulation and basal vitamin D receptor expression in human osteoblastic cells according to donor age and skeletal origin
    • Martinez P, Moreno I, De Miguel F, Vila V, Esbrit P, Martinez ME (2001) Changes in osteocalcin response to 1,25-dihydroxyvitamin D(3) stimulation and basal vitamin D receptor expression in human osteoblastic cells according to donor age and skeletal origin. Bone 29, 35-41.
    • (2001) Bone , vol.29 , pp. 35-41
    • Martinez, P.1    Moreno, I.2    De Miguel, F.3    Vila, V.4    Esbrit, P.5    Martinez, M.E.6
  • 17
    • 18044373421 scopus 로고    scopus 로고
    • Dyskeratosis congenita - A disease of dysfunctional telomere maintenance
    • Mason PJ, Wilson DB, Bessler M (2005) Dyskeratosis congenita - a disease of dysfunctional telomere maintenance. Curr. Mol. Med. 5, 159-170.
    • (2005) Curr. Mol. Med. , vol.5 , pp. 159-170
    • Mason, P.J.1    Wilson, D.B.2    Bessler, M.3
  • 19
    • 33846121333 scopus 로고    scopus 로고
    • Vascular cell senescence: Contribution to atherosclerosis
    • Minamino T, Komuro I (2007) Vascular cell senescence: Contribution to atherosclerosis. Circ. Res. 100, 15-26.
    • (2007) Circ. Res. , vol.100 , pp. 15-26
    • Minamino, T.1    Komuro, I.2
  • 20
    • 0035069575 scopus 로고    scopus 로고
    • Age- and gender-related changes in the cellularity of human bone marrow and the prevalence of osteoblastic progenitors
    • Muschler GF, Nitto H, Boehm CA, Easley KA (2001) Age- and gender-related changes in the cellularity of human bone marrow and the prevalence of osteoblastic progenitors. J. Orthop. Res. 19, 117-125.
    • (2001) J. Orthop. Res. , vol.19 , pp. 117-125
    • Muschler, G.F.1    Nitto, H.2    Boehm, C.A.3    Easley, K.A.4
  • 21
    • 0032805375 scopus 로고    scopus 로고
    • Number of osteoprogenitor cells in human bone marrow markedly decreases after skeletal maturation
    • Nishida S, Endo N, Yamagiwa H, Tanizawa T, Takahashi HE (1999) Number of osteoprogenitor cells in human bone marrow markedly decreases after skeletal maturation. J. Bone Miner. Metab. 17, 171-177.
    • (1999) J. Bone Miner. Metab. , vol.17 , pp. 171-177
    • Nishida, S.1    Endo, N.2    Yamagiwa, H.3    Tanizawa, T.4    Takahashi, H.E.5
  • 22
    • 0037175018 scopus 로고    scopus 로고
    • Telomere-binding protein TRF2 binds to and stimulates the Werner and Bloom syndrome helicases
    • Opresko PL, von Kobbe C, Laine JP, Harrigan J, Hickson ID, Bohr VA (2002) Telomere-binding protein TRF2 binds to and stimulates the Werner and Bloom syndrome helicases. J. Biol. Chem. 277, 41110-41119.
    • (2002) J. Biol. Chem. , vol.277 , pp. 41110-41119
    • Opresko, P.L.1    von Kobbe, C.2    Laine, J.P.3    Harrigan, J.4    Hickson, I.D.5    Bohr, V.A.6
  • 23
    • 24044521924 scopus 로고    scopus 로고
    • Current advances in unraveling the function of the Werner syndrome protein
    • Ozgenc A, Loeb LA (2005) Current advances in unraveling the function of the Werner syndrome protein. Mutat. Res. 577, 237-251.
    • (2005) Mutat. Res. , vol.577 , pp. 237-251
    • Ozgenc, A.1    Loeb, L.A.2
  • 25
    • 0019444282 scopus 로고
    • Systematic growth studies, cocultivation, and cell hybridization studies of Werner syndrome cultured skin fibroblasts
    • Salk D, Bryant E, Au K, Hoehn H, Martin GM (1981) Systematic growth studies, cocultivation, and cell hybridization studies of Werner syndrome cultured skin fibroblasts. Hum. Genet. 58, 310-316.
    • (1981) Hum. Genet. , vol.58 , pp. 310-316
    • Salk, D.1    Bryant, E.2    Au, K.3    Hoehn, H.4    Martin, G.M.5
  • 26
    • 0035984715 scopus 로고    scopus 로고
    • Bone formation by human postnatal bone marrow stromal stem cells is enhanced by telomerase expression
    • Shi S, Gronthos S, Chen S, Reddi A, Counter CM, Robey PG, Wang CY (2002) Bone formation by human postnatal bone marrow stromal stem cells is enhanced by telomerase expression. Nat. Biotechnol. 20, 587-591.
    • (2002) Nat. Biotechnol. , vol.20 , pp. 587-591
    • Shi, S.1    Gronthos, S.2    Chen, S.3    Reddi, A.4    Counter, C.M.5    Robey, P.G.6    Wang, C.Y.7
  • 27
    • 15844425858 scopus 로고
    • Osteoarthrosis and osteoporosis in senile mice
    • Silberberg M, Silberberg R (1962) Osteoarthrosis and osteoporosis in senile mice. Gerontologia 6, 91-101.
    • (1962) Gerontologia , vol.6 , pp. 91-101
    • Silberberg, M.1    Silberberg, R.2
  • 29
    • 0035010576 scopus 로고    scopus 로고
    • Number and proliferative capacity of osteogenic stem cells are maintained during aging and in patients with osteoporosis
    • Stenderup K, Justesen J, Eriksen EF, Rattan SI, Kassem M (2001) Number and proliferative capacity of osteogenic stem cells are maintained during aging and in patients with osteoporosis. J. Bone Miner. Res. 16, 1120-1129.
    • (2001) J. Bone Miner. Res. , vol.16 , pp. 1120-1129
    • Stenderup, K.1    Justesen, J.2    Eriksen, E.F.3    Rattan, S.I.4    Kassem, M.5
  • 32
    • 0034925471 scopus 로고    scopus 로고
    • Reconstituting telomerase activity using the telomerase catalytic subunit prevents the telomere shorting and replicative senescence in human osteoblasts
    • Yudoh K, Matsuno H, Nakazawa F, Katayama R, Kimura T (2001) Reconstituting telomerase activity using the telomerase catalytic subunit prevents the telomere shorting and replicative senescence in human osteoblasts. J. Bone Miner. Res. 16, 1453-1464.
    • (2001) J. Bone Miner. Res. , vol.16 , pp. 1453-1464
    • Yudoh, K.1    Matsuno, H.2    Nakazawa, F.3    Katayama, R.4    Kimura, T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.