Telomere fluorescence measurements in granulocytes and T lymphocyte subsets point to a high turnover of hematopoietic stem cells and memory T cells in early childhood

Journal of Experimental Medicine

Volumn 190, Issue 2, 1999, Pages 157-167

  Rufer, Nathalie ^a   Brümmendorf, Tim H ^a   Kolvraa, Steen ^b   Bischoff, Claus ^b   Christensen, Kaare ^c   Wadsworth, Louis ^d,e   Schulzer, Michael ^e   Lansdorp, Peter M ^a,e  

^a BRITISH COLUMBIA CANCER AGENCY   (Canada)

^b AARHUS UNIVERSITY   (Denmark)

^c UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^d BC CHILDREN S HOSPITAL   (Canada)

^e UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Cellular turnover; Immune senescence; Stem cell self renewal; Telomere length dynamics; Telomere length inheritance

Indexed keywords

AGING; ARTICLE; CELL DIVISION; CELL RENEWAL; CHROMOSOME SIZE; DIZYGOTIC TWINS; FLOW CYTOMETRY; FLUORESCENCE IN SITU HYBRIDIZATION; GRANULOCYTE; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; MEMORY CELL; MONOZYGOTIC TWINS; PRIORITY JOURNAL; T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION; TELOMERE;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; AGING; CHILD; CHILD, PRESCHOOL; FEMALE; FLOW CYTOMETRY; GRANULOCYTES; HEMATOPOIETIC STEM CELLS; HUMANS; IMMUNOLOGIC MEMORY; IN SITU HYBRIDIZATION, FLUORESCENCE; INFANT; INFANT, NEWBORN; MALE; MIDDLE AGED; T-LYMPHOCYTE SUBSETS; TELOMERE; TERMINAL REPEAT SEQUENCES; TWINS, DIZYGOTIC; TWINS, MONOZYGOTIC;

EID: 0345643319     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.190.2.157     Document Type: Article

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