-
1
-
-
0000293742
-
Über eine eigenartige Erkrankung der Hirnrinde
-
Alzheimer A. Über eine eigenartige Erkrankung der Hirnrinde. Zeitschrift für Psychiatrie 64: 146-148 (1907).
-
(1907)
Zeitschrift Für Psychiatrie
, vol.64
, pp. 146-148
-
-
Alzheimer, A.1
-
2
-
-
0031720801
-
The incidence of dementia: A meta-analysis
-
Jorm AF, Jolley D. The incidence of dementia: a meta-analysis. Neurology 51: 728-33 (1998).
-
(1998)
Neurology
, vol.51
, pp. 728-733
-
-
Jorm, A.F.1
Jolley, D.2
-
3
-
-
33750361022
-
Aging of the brain, entropy, and Alzheimer disease
-
Drachman DA. Aging of the brain, entropy, and Alzheimer disease. Neurology 67: 1340-52 (2006).
-
(2006)
Neurology
, vol.67
, pp. 1340-1352
-
-
Drachman, D.A.1
-
4
-
-
72849142054
-
Alzheimer's disease: Synaptic dysfunction and Abeta
-
Shankar GM, Walsh DM. Alzheimer's disease: synaptic dysfunction and Abeta. Mol Neurodegener 4: 48 (2009).
-
(2009)
Mol Neurodegener
, vol.4
, pp. 48
-
-
Shankar, G.M.1
Walsh, D.M.2
-
5
-
-
33847135229
-
Serotonin 5-HT2A and 5-HT6 receptors in the prefrontal cortex of Alzheimer and normal aging patients
-
Lorke DE, Lu G, Cho E, Yew DT. Serotonin 5-HT2A and 5-HT6 receptors in the prefrontal cortex of Alzheimer and normal aging patients. BMC Neurosci 7: 36 (2006).
-
(2006)
BMC Neurosci
, vol.7
, pp. 36
-
-
Lorke, D.E.1
Lu, G.2
Cho, E.3
Yew, D.T.4
-
6
-
-
0344653664
-
Neuronal loss correlates with but exceeds neurofibrillary tangles in Alzheimer's disease
-
Gomez-Isla T, Hollister R, West H, Mui S, Growdon JH, Petersen RC, et al. Neuronal loss correlates with but exceeds neurofibrillary tangles in Alzheimer's disease. Ann Neurol 41: 17-24 (1997).
-
(1997)
Ann Neurol
, vol.41
, pp. 17-24
-
-
Gomez-Isla, T.1
Hollister, R.2
West, H.3
Mui, S.4
Growdon, J.H.5
Petersen, R.C.6
-
7
-
-
33749177143
-
A hundred years of Alzheimer's disease research
-
Hardy J. A hundred years of Alzheimer's disease research. Neuron 52: 3-13 (2006).
-
(2006)
Neuron
, vol.52
, pp. 3-13
-
-
Hardy, J.1
-
8
-
-
0025863618
-
Neuropathological stageing of Alzheimerrelated changes
-
Braak H, Braak E. Neuropathological stageing of Alzheimerrelated changes. Acta Neuropathol 82: 239-59 (1991).
-
(1991)
Acta Neuropathol
, vol.82
, pp. 239-259
-
-
Braak, H.1
Braak, E.2
-
9
-
-
77951753692
-
TUNEL and growth factor expression in the prefrontal cortex of Alzheimer patients over 80 years old
-
Lorke DE, Wai MS, Liang Y, Yew DT. TUNEL and growth factor expression in the prefrontal cortex of Alzheimer patients over 80 years old. Int J Immunopathol Pharmacol 23: 13-23 (2010).
-
(2010)
Int J Immunopathol Pharmacol
, vol.23
, pp. 13-23
-
-
Lorke, D.E.1
Wai, M.S.2
Liang, Y.3
Yew, D.T.4
-
10
-
-
79959685557
-
Cell cycle deregulation in the neurons of Alzheimer's disease
-
Moh C, Kubiak JZ, Bajic VP, Zhu X, Smith MA, Lee HG. Cell cycle deregulation in the neurons of Alzheimer's disease. Results Probl Cell Differ 53: 565-76 (2011).
-
(2011)
Results Probl Cell Differ
, vol.53
, pp. 565-576
-
-
Moh, C.1
Kubiak, J.Z.2
Bajic, V.P.3
Zhu, X.4
Smith, M.A.5
Lee, H.G.6
-
11
-
-
0001181116
-
Alzheimer's disease: Molecular understanding predicts amyloid-based therapeutics
-
Selkoe DJ, Schenk D. Alzheimer's disease: molecular understanding predicts amyloid-based therapeutics. Annu Rev Pharmacol Toxicol 43: 545-84 (2003).
-
(2003)
Annu Rev Pharmacol Toxicol
, vol.43
, pp. 545-584
-
-
Selkoe, D.J.1
Schenk, D.2
-
12
-
-
84877968410
-
Amyloid-beta Peptide: Dr. Jekyll or Mr. Hyde?
-
Puzzo D, Arancio O. Amyloid-beta Peptide: Dr. Jekyll or Mr. Hyde? J Alzheimers Dis (2012).
-
(2012)
J Alzheimers Dis
-
-
Puzzo, D.1
Arancio, O.2
-
13
-
-
0032814135
-
Alzheimer's disease and the amyloid beta protein: What is the role of amyloid?
-
Small DH, McLean CA. Alzheimer's disease and the amyloid beta protein: What is the role of amyloid? J Neurochem 73: 443-9 (1999).
-
(1999)
J Neurochem
, vol.73
, pp. 443-449
-
-
Small, D.H.1
McLean, C.A.2
-
14
-
-
0042634362
-
Roles of amyloid precursor protein and its fragments in regulating neural activity, plasticity and memory
-
Turner PR, O'Connor K, Tate WP, Abraham WC. Roles of amyloid precursor protein and its fragments in regulating neural activity, plasticity and memory. Prog Neurobiol 70: 1-32 (2003).
-
(2003)
Prog Neurobiol
, vol.70
, pp. 1-32
-
-
Turner, P.R.1
O'Connor, K.2
Tate, W.P.3
Abraham, W.C.4
-
15
-
-
33745700370
-
Mean age-of-onset of familial alzheimer disease caused by presenilin mutations correlates with both increased Abeta42 and decreased Abeta40
-
Kumar-Singh S, Theuns J, Van Broeck B, Pirici D, Vennekens K, Corsmit E, et al. Mean age-of-onset of familial alzheimer disease caused by presenilin mutations correlates with both increased Abeta42 and decreased Abeta40. Hum Mutat 27: 686-95 (2006).
-
(2006)
Hum Mutat
, vol.27
, pp. 686-695
-
-
Kumar-Singh, S.1
Theuns, J.2
Van Broeck, B.3
Pirici, D.4
Vennekens, K.5
Corsmit, E.6
-
17
-
-
58149497521
-
Biochemistry and molecular biology of amyloid betaprotein and the mechanism of Alzheimer's disease
-
Selkoe DJ. Biochemistry and molecular biology of amyloid betaprotein and the mechanism of Alzheimer's disease. Handb Clin Neurol 89: 245-60 (2008).
-
(2008)
Handb Clin Neurol
, vol.89
, pp. 245-260
-
-
Selkoe, D.J.1
-
18
-
-
0034728596
-
Quantitative assessment of nicotinic acetylcholine receptor proteins in the cerebral cortex of Alzheimer patients
-
Burghaus L, Schutz U, Krempel U, de Vos RA, Jansen Steur EN, Wevers A, et al. Quantitative assessment of nicotinic acetylcholine receptor proteins in the cerebral cortex of Alzheimer patients. Brain Res Mol Brain Res 76: 385-8 (2000).
-
(2000)
Brain Res Mol Brain Res
, vol.76
, pp. 385-388
-
-
Burghaus, L.1
Schutz, U.2
Krempel, U.3
de Vos, R.A.4
Jansen Steur, E.N.5
Wevers, A.6
-
19
-
-
0035251750
-
Nicotinic receptor abnormalities in Alzheimer's disease
-
Court J, Martin-Ruiz C, Piggott M, Spurden D, Griffiths M, Perry E. Nicotinic receptor abnormalities in Alzheimer's disease. Biol Psychiatry 49: 175-84 (2001).
-
(2001)
Biol Psychiatry
, vol.49
, pp. 175-184
-
-
Court, J.1
Martin-Ruiz, C.2
Piggott, M.3
Spurden, D.4
Griffiths, M.5
Perry, E.6
-
20
-
-
0033841591
-
Expression of nicotinic acetylcholine receptors in Alzheimer's disease: Postmortem investigations and experimental approaches
-
Wevers A, Burghaus L, Moser N, Witter B, Steinlein OK, Schutz U, et al. Expression of nicotinic acetylcholine receptors in Alzheimer's disease: postmortem investigations and experimental approaches. Behav Brain Res 113: 207-15 (2000).
-
(2000)
Behav Brain Res
, vol.113
, pp. 207-215
-
-
Wevers, A.1
Burghaus, L.2
Moser, N.3
Witter, B.4
Steinlein, O.K.5
Schutz, U.6
-
21
-
-
0032589299
-
Alpha4 but not alpha3 and alpha7 nicotinic acetylcholine receptor subunits are lost from the temporal cortex in Alzheimer's disease
-
Martin-Ruiz CM, Court JA, Molnar E, Lee M, Gotti C, Mamalaki A, et al. Alpha4 but not alpha3 and alpha7 nicotinic acetylcholine receptor subunits are lost from the temporal cortex in Alzheimer's disease. J Neurochem 73: 1635-40 (1999).
-
(1999)
J Neurochem
, vol.73
, pp. 1635-1640
-
-
Martin-Ruiz, C.M.1
Court, J.A.2
Molnar, E.3
Lee, M.4
Gotti, C.5
Mamalaki, A.6
-
22
-
-
0035232357
-
Changes in nicotinic acetylcholine receptor subunits expression in brain of patients with Down syndrome and Alzheimer's disease
-
Engidawork E, Gulesserian T, Balic N, Cairns N, Lubec G. Changes in nicotinic acetylcholine receptor subunits expression in brain of patients with Down syndrome and Alzheimer's disease. J Neural Transm Suppl 211-22 (2001).
-
(2001)
J Neural Transm Suppl
, pp. 211-222
-
-
Engidawork, E.1
Gulesserian, T.2
Balic, N.3
Cairns, N.4
Lubec, G.5
-
23
-
-
0033983966
-
Decreased protein levels of nicotinic receptor subunits in the hippocampus and temporal cortex of patients with Alzheimer's disease
-
Guan ZZ, Zhang X, Ravid R, Nordberg A. Decreased protein levels of nicotinic receptor subunits in the hippocampus and temporal cortex of patients with Alzheimer's disease. J Neurochem 74: 237-43 (2000).
-
(2000)
J Neurochem
, vol.74
, pp. 237-243
-
-
Guan, Z.Z.1
Zhang, X.2
Ravid, R.3
Nordberg, A.4
-
24
-
-
0019521132
-
Postmortem stability of alpha-bungarotoxin binding sites in mouse and human brain
-
Davies P, Feisullin S. Postmortem stability of alpha-bungarotoxin binding sites in mouse and human brain. Brain Res 216: 449-54 (1981).
-
(1981)
Brain Res
, vol.216
, pp. 449-454
-
-
Davies, P.1
Feisullin, S.2
-
25
-
-
33847029091
-
Nicotinic acetylcholine receptors and nicotinic cholinergic mechanisms of the central nervous system
-
Dani JA, Bertrand D. Nicotinic acetylcholine receptors and nicotinic cholinergic mechanisms of the central nervous system. Annu Rev Pharmacol Toxicol 47: 699-729 (2007).
-
(2007)
Annu Rev Pharmacol Toxicol
, vol.47
, pp. 699-729
-
-
Dani, J.A.1
Bertrand, D.2
-
26
-
-
0141748121
-
Nicotinic acetylcholine receptors of muscles and nerves: Comparison of their structures, functional roles, and vulnerability to pathology
-
Lindstrom JM. Nicotinic acetylcholine receptors of muscles and nerves: comparison of their structures, functional roles, and vulnerability to pathology. Ann N Y Acad Sci 998: 41-52 (2003).
-
(2003)
Ann N Y Acad Sci
, vol.998
, pp. 41-52
-
-
Lindstrom, J.M.1
-
28
-
-
33846029827
-
Dissecting the signaling pathway of nicotine-mediated neuroprotection in a mouse Alzheimer disease model
-
Liu Q, Zhang J, Zhu H, Qin C, Chen Q, Zhao B. Dissecting the signaling pathway of nicotine-mediated neuroprotection in a mouse Alzheimer disease model. FASEB J 21: 61-73 (2007).
-
(2007)
FASEB J
, vol.21
, pp. 61-73
-
-
Liu, Q.1
Zhang, J.2
Zhu, H.3
Qin, C.4
Chen, Q.5
Zhao, B.6
-
29
-
-
0025605864
-
A neuronal nicotinic acetylcholine receptor subunit (alpha 7) is developmentally regulated and forms a homooligomeric channel blocked by alpha-BTX
-
Couturier S, Bertrand D, Matter JM, Hernandez MC, Bertrand S, Millar N, et al. A neuronal nicotinic acetylcholine receptor subunit (alpha 7) is developmentally regulated and forms a homooligomeric channel blocked by alpha-BTX. Neuron 5: 847-56 (1990).
-
(1990)
Neuron
, vol.5
, pp. 847-856
-
-
Couturier, S.1
Bertrand, D.2
Matter, J.M.3
Hernandez, M.C.4
Bertrand, S.5
Millar, N.6
-
30
-
-
0027518923
-
Molecular cloning, functional properties, and distribution of rat brain alpha 7: A nicotinic cation channel highly permeable to calcium
-
Seguela P, Wadiche J, Dineley-Miller K, Dani JA, Patrick JW. Molecular cloning, functional properties, and distribution of rat brain alpha 7: a nicotinic cation channel highly permeable to calcium. J Neurosci 13: 596-604 (1993).
-
(1993)
J Neurosci
, vol.13
, pp. 596-604
-
-
Seguela, P.1
Wadiche, J.2
Dineley-Miller, K.3
Dani, J.A.4
Patrick, J.W.5
-
31
-
-
77449137869
-
Modulation of transmitter release via presynaptic ligand-gated ion channels
-
Schicker KW, Dorostkar MM, Boehm S. Modulation of transmitter release via presynaptic ligand-gated ion channels. Curr Mol Pharmacol 1: 106-29 (2008).
-
(2008)
Curr Mol Pharmacol
, vol.1
, pp. 106-129
-
-
Schicker, K.W.1
Dorostkar, M.M.2
Boehm, S.3
-
33
-
-
0027257837
-
Autoradiographic comparison of cholinergic and other transmitter receptors in the normal human hippocampus
-
Perry EK, Court JA, Johnson M, Smith CJ, James V, Cheng AV, et al. Autoradiographic comparison of cholinergic and other transmitter receptors in the normal human hippocampus. Hippocampus 3: 307-15 (1993).
-
(1993)
Hippocampus
, vol.3
, pp. 307-315
-
-
Perry, E.K.1
Court, J.A.2
Johnson, M.3
Smith, C.J.4
James, V.5
Cheng, A.V.6
-
34
-
-
0029805769
-
Hippocampal synaptic transmission enhanced by low concentrations of nicotine
-
Gray R, Rajan AS, Radcliffe KA, Yakehiro M, Dani JA. Hippocampal synaptic transmission enhanced by low concentrations of nicotine. Nature 383: 713-6 (1996).
-
(1996)
Nature
, vol.383
, pp. 713-716
-
-
Gray, R.1
Rajan, A.S.2
Radcliffe, K.A.3
Yakehiro, M.4
Dani, J.A.5
-
35
-
-
0032520135
-
Acetylcholine activates an alpha-bungarotoxinsensitive nicotinic current in rat hippocampal interneurons, but not pyramidal cells
-
Frazier CJ, Rollins YD, Breese CR, Leonard S, Freedman R, Dunwiddie TV. Acetylcholine activates an alpha-bungarotoxinsensitive nicotinic current in rat hippocampal interneurons, but not pyramidal cells. J Neurosci 18: 1187-95 (1998).
-
(1998)
J Neurosci
, vol.18
, pp. 1187-1195
-
-
Frazier, C.J.1
Rollins, Y.D.2
Breese, C.R.3
Leonard, S.4
Freedman, R.5
Dunwiddie, T.V.6
-
36
-
-
65249151342
-
Genetic variation in the alpha 7 nicotinic acetylcholine receptor is associated with delusional symptoms in Alzheimer's disease
-
Carson R, Craig D, Hart D, Todd S, McGuinness B, Johnston JA, et al. Genetic variation in the alpha 7 nicotinic acetylcholine receptor is associated with delusional symptoms in Alzheimer's disease. Neuromolecular Med 10: 377-84 (2008).
-
(2008)
Neuromolecular Med
, vol.10
, pp. 377-384
-
-
Carson, R.1
Craig, D.2
Hart, D.3
Todd, S.4
McGuinness, B.5
Johnston, J.A.6
-
37
-
-
0035251677
-
Nicotinic receptor abnormalities of Alzheimer's disease: Therapeutic implications
-
Nordberg A. Nicotinic receptor abnormalities of Alzheimer's disease: therapeutic implications. Biol Psychiatry 49: 200-10 (2001).
-
(2001)
Biol Psychiatry
, vol.49
, pp. 200-210
-
-
Nordberg, A.1
-
38
-
-
0032971370
-
Expression of nicotinic acetylcholine receptor subunits in the cerebral cortex in Alzheimer's disease: Histotopographical correlation with amyloid plaques and hyperphosphorylated-tau protein
-
Wevers A, Monteggia L, Nowacki S, Bloch W, Schutz U, Lindstrom J, et al. Expression of nicotinic acetylcholine receptor subunits in the cerebral cortex in Alzheimer's disease: histotopographical correlation with amyloid plaques and hyperphosphorylated-tau protein. Eur J Neurosci 11: 2551-65 (1999).
-
(1999)
Eur J Neurosci
, vol.11
, pp. 2551-2565
-
-
Wevers, A.1
Monteggia, L.2
Nowacki, S.3
Bloch, W.4
Schutz, U.5
Lindstrom, J.6
-
39
-
-
37149055806
-
Alpha7 nicotinic receptor up-regulation in cholinergic basal forebrain neurons in Alzheimer disease
-
Counts SE, He B, Che S, Ikonomovic MD, DeKosky ST, Ginsberg SD, et al. Alpha7 nicotinic receptor up-regulation in cholinergic basal forebrain neurons in Alzheimer disease. Arch Neurol 64: 1771-6 (2007).
-
(2007)
Arch Neurol
, vol.64
, pp. 1771-1776
-
-
Counts, S.E.1
He, B.2
Che, S.3
Ikonomovic, M.D.4
Dekosky, S.T.5
Ginsberg, S.D.6
-
40
-
-
33645319504
-
Targeting the alpha 7 nicotinic acetylcholine receptor to reduce amyloid accumulation in Alzheimer's disease pyramidal neurons
-
D'Andrea MR, Nagele RG. Targeting the alpha 7 nicotinic acetylcholine receptor to reduce amyloid accumulation in Alzheimer's disease pyramidal neurons. Curr Pharm Des 12: 677-84 (2006).
-
(2006)
Curr Pharm Des
, vol.12
, pp. 677-684
-
-
D'Andrea, M.R.1
Nagele, R.G.2
-
41
-
-
33746267516
-
Selective nicotinic acetylcholine receptor subunit deficits identified in Alzheimer's disease, Parkinson's disease and dementia with Lewy bodies by immunoprecipitation
-
Gotti C, Moretti M, Bohr I, Ziabreva I, Vailati S, Longhi R, et al. Selective nicotinic acetylcholine receptor subunit deficits identified in Alzheimer's disease, Parkinson's disease and dementia with Lewy bodies by immunoprecipitation. Neurobiol Dis 23: 481-9 (2006).
-
(2006)
Neurobiol Dis
, vol.23
, pp. 481-489
-
-
Gotti, C.1
Moretti, M.2
Bohr, I.3
Ziabreva, I.4
Vailati, S.5
Longhi, R.6
-
42
-
-
33845535334
-
Pathologic and nicotinic receptor binding differences between mild cognitive impairment, Alzheimer disease, and normal aging
-
Sabbagh MN, Shah F, Reid RT, Sue L, Connor DJ, Peterson LK, et al. Pathologic and nicotinic receptor binding differences between mild cognitive impairment, Alzheimer disease, and normal aging. Arch Neurol 63: 1771-6 (2006).
-
(2006)
Arch Neurol
, vol.63
, pp. 1771-1776
-
-
Sabbagh, M.N.1
Shah, F.2
Reid, R.T.3
Sue, L.4
Connor, D.J.5
Peterson, L.K.6
-
43
-
-
0034006944
-
beta-Amyloid(1-42) binds to alpha7 nicotinic acetylcholine receptor with high affinity. Implications for Alzheimer's disease pathology
-
Wang HY, Lee DH, D'Andrea MR, Peterson PA, Shank RP, Reitz AB. beta-Amyloid(1-42) binds to alpha7 nicotinic acetylcholine receptor with high affinity. Implications for Alzheimer's disease pathology. J Biol Chem 275: 5626-32 (2000).
-
(2000)
J Biol Chem
, vol.275
, pp. 5626-5632
-
-
Wang, H.Y.1
Lee, D.H.2
D'Andrea, M.R.3
Peterson, P.A.4
Shank, R.P.5
Reitz, A.B.6
-
44
-
-
0033624509
-
Amyloid peptide Abeta(1-42) binds selectively and with picomolar affinity to alpha7 nicotinic acetylcholine receptors
-
Wang HY, Lee DH, Davis CB, Shank RP. Amyloid peptide Abeta(1-42) binds selectively and with picomolar affinity to alpha7 nicotinic acetylcholine receptors. J Neurochem 75: 1155-61 (2000).
-
(2000)
J Neurochem
, vol.75
, pp. 1155-1161
-
-
Wang, H.Y.1
Lee, D.H.2
Davis, C.B.3
Shank, R.P.4
-
45
-
-
0037066072
-
Intracellular accumulation of beta-amyloid(1-42) in neurons is facilitated by the alpha 7 nicotinic acetylcholine receptor in Alzheimer's disease
-
Nagele RG, D'Andrea MR, Anderson WJ, Wang HY. Intracellular accumulation of beta-amyloid(1-42) in neurons is facilitated by the alpha 7 nicotinic acetylcholine receptor in Alzheimer's disease. Neuroscience 110: 199-211 (2002).
-
(2002)
Neuroscience
, vol.110
, pp. 199-211
-
-
Nagele, R.G.1
D'Andrea, M.R.2
Anderson, W.J.3
Wang, H.Y.4
-
46
-
-
4043167747
-
Abeta immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome
-
Oddo S, Billings L, Kesslak JP, Cribbs DH, LaFerla FM. Abeta immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome. Neuron 43: 321-32 (2004).
-
(2004)
Neuron
, vol.43
, pp. 321-332
-
-
Oddo, S.1
Billings, L.2
Kesslak, J.P.3
Cribbs, D.H.4
Laferla, F.M.5
-
47
-
-
0027461090
-
An amyloid peptide, beta A4 25-35, mimics the function of substance P on modulation of nicotine-evoked secretion and desensitization in cultured bovine adrenal chromaffin cells
-
Cheung NS, Small DH, Livett BG. An amyloid peptide, beta A4 25-35, mimics the function of substance P on modulation of nicotine-evoked secretion and desensitization in cultured bovine adrenal chromaffin cells. J Neurochem 60: 1163-6 (1993).
-
(1993)
J Neurochem
, vol.60
, pp. 1163-1166
-
-
Cheung, N.S.1
Small, D.H.2
Livett, B.G.3
-
48
-
-
0042357192
-
Alpha 7 nicotinic acetylcholine receptors mediate beta-amyloid peptide-induced tau protein phosphorylation
-
Wang HY, Li W, Benedetti NJ, Lee DH. Alpha 7 nicotinic acetylcholine receptors mediate beta-amyloid peptide-induced tau protein phosphorylation. J Biol Chem 278: 31547-53 (2003).
-
(2003)
J Biol Chem
, vol.278
, pp. 31547-31553
-
-
Wang, H.Y.1
Li, W.2
Benedetti, N.J.3
Lee, D.H.4
-
49
-
-
34249823327
-
The beta-amyloid protein of Alzheimer's disease binds to membrane lipids but does not bind to the alpha7 nicotinic acetylcholine receptor
-
Small DH, Maksel D, Kerr ML, Ng J, Hou X, Chu C, et al. The beta-amyloid protein of Alzheimer's disease binds to membrane lipids but does not bind to the alpha7 nicotinic acetylcholine receptor. J Neurochem 101: 1527-38 (2007).
-
(2007)
J Neurochem
, vol.101
, pp. 1527-1538
-
-
Small, D.H.1
Maksel, D.2
Kerr, M.L.3
Ng, J.4
Hou, X.5
Chu, C.6
-
50
-
-
5444257609
-
MAPK recruitment by beta-amyloid in organotypic hippocampal slice cultures depends on physical state and exposure time
-
Bell KA, O'Riordan KJ, Sweatt JD, Dineley KT. MAPK recruitment by beta-amyloid in organotypic hippocampal slice cultures depends on physical state and exposure time. J Neurochem 91: 349-61 (2004).
-
(2004)
J Neurochem
, vol.91
, pp. 349-361
-
-
Bell, K.A.1
O'Riordan, K.J.2
Sweatt, J.D.3
Dineley, K.T.4
-
51
-
-
77957257176
-
Stabilization of neurotoxic Alzheimer amyloid-beta oligomers by protein engineering
-
Sandberg A, Luheshi LM, Sollvander S, Pereira de Barros T, Macao B, Knowles TP, et al. Stabilization of neurotoxic Alzheimer amyloid-beta oligomers by protein engineering. Proc Natl Acad Sci USA 107: 15595-600 (2010).
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 15595-15600
-
-
Sandberg, A.1
Luheshi, L.M.2
Sollvander, S.3
Pereira de Barros, T.4
Macao, B.5
Knowles, T.P.6
-
52
-
-
0037041426
-
Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo
-
Walsh DM, Klyubin I, Fadeeva JV, Cullen WK, Anwyl R, Wolfe MS, et al. Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo. Nature 416: 535-9 (2002).
-
(2002)
Nature
, vol.416
, pp. 535-539
-
-
Walsh, D.M.1
Klyubin, I.2
Fadeeva, J.V.3
Cullen, W.K.4
Anwyl, R.5
Wolfe, M.S.6
-
53
-
-
80053215529
-
Role of key aromatic residues in the ligand-binding domain of alpha7 nicotinic receptors in the agonist action of beta-amyloid
-
Tong M, Arora K, White MM, Nichols RA. Role of key aromatic residues in the ligand-binding domain of alpha7 nicotinic receptors in the agonist action of beta-amyloid. J Biol Chem 286: 34373-81 (2011).
-
(2011)
J Biol Chem
, vol.286
, pp. 34373-34381
-
-
Tong, M.1
Arora, K.2
White, M.M.3
Nichols, R.A.4
-
54
-
-
0027772476
-
Chimaeric nicotinic-serotonergic receptor combines distinct ligand binding and channel specificities
-
Eisele JL, Bertrand S, Galzi JL, Devillers-Thiery A, Changeux JP, Bertrand D. Chimaeric nicotinic-serotonergic receptor combines distinct ligand binding and channel specificities. Nature 366: 479-83 (1993).
-
(1993)
Nature
, vol.366
, pp. 479-483
-
-
Eisele, J.L.1
Bertrand, S.2
Galzi, J.L.3
Devillers-Thiery, A.4
Changeux, J.P.5
Bertrand, D.6
-
55
-
-
35348820536
-
Identification of domains influencing assembly and ion channel properties in alpha 7 nicotinic receptor and 5-HT3 receptor subunit chimaeras
-
Gee VJ, Kracun S, Cooper ST, Gibb AJ, Millar NS. Identification of domains influencing assembly and ion channel properties in alpha 7 nicotinic receptor and 5-HT3 receptor subunit chimaeras. Br J Pharmacol 152: 501-12 (2007).
-
(2007)
Br J Pharmacol
, vol.152
, pp. 501-512
-
-
Gee, V.J.1
Kracun, S.2
Cooper, S.T.3
Gibb, A.J.4
Millar, N.S.5
-
56
-
-
0035836747
-
beta-Amyloid peptide blocks the response of alpha 7-containing nicotinic receptors on hippocampal neurons
-
Liu Q, Kawai H, Berg DK. beta-Amyloid peptide blocks the response of alpha 7-containing nicotinic receptors on hippocampal neurons. Proc Natl Acad Sci USA 98: 4734-9 (2001).
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 4734-4739
-
-
Liu, Q.1
Kawai, H.2
Berg, D.K.3
-
57
-
-
0031025811
-
Volatile general anaesthetic actions on recombinant nACh alpha 7, 5-HT3 and chimeric nACh alpha 7-5-HT3 receptors expressed in Xenopus oocytes
-
Zhang L, Oz M, Stewart RR, Peoples RW, Weight FF. Volatile general anaesthetic actions on recombinant nACh alpha 7, 5-HT3 and chimeric nACh alpha 7-5-HT3 receptors expressed in Xenopus oocytes. Br J Pharmacol 120: 353-5 (1997).
-
(1997)
Br J Pharmacol
, vol.120
, pp. 353-355
-
-
Zhang, L.1
Oz, M.2
Stewart, R.R.3
Peoples, R.W.4
Weight, F.F.5
-
58
-
-
0043135255
-
Beta-amyloid regulation of presynaptic nicotinic receptors in rat hippocampus and neocortex
-
Dougherty JJ, Wu J, Nichols RA. Beta-amyloid regulation of presynaptic nicotinic receptors in rat hippocampus and neocortex. J Neurosci 23: 6740-7 (2003).
-
(2003)
J Neurosci
, vol.23
, pp. 6740-6747
-
-
Dougherty, J.J.1
Wu, J.2
Nichols, R.A.3
-
59
-
-
0026758178
-
Mutational analysis of ligand-induced activation of the Torpedo acetylcholine receptor
-
O'Leary ME, White MM. Mutational analysis of ligand-induced activation of the Torpedo acetylcholine receptor. J Biol Chem 267: 8360-5 (1992).
-
(1992)
J Biol Chem
, vol.267
, pp. 8360-8365
-
-
O'Leary, M.E.1
White, M.M.2
-
60
-
-
75049084818
-
Boundary lipids in the nicotinic acetylcholine receptor microenvironment
-
Barrantes FJ, Bermudez V, Borroni MV, Antollini SS, Pediconi MF, Baier JC, et al. Boundary lipids in the nicotinic acetylcholine receptor microenvironment. J Mol Neurosci 40: 87-90 (2010).
-
(2010)
J Mol Neurosci
, vol.40
, pp. 87-90
-
-
Barrantes, F.J.1
Bermudez, V.2
Borroni, M.V.3
Antollini, S.S.4
Pediconi, M.F.5
Baier, J.C.6
-
61
-
-
79955051063
-
Linking lipids to Alzheimer's disease: Cholesterol and beyond
-
Di Paolo G, Kim TW. Linking lipids to Alzheimer's disease: cholesterol and beyond. Nat Rev Neurosci 12: 284-96 (2011).
-
(2011)
Nat Rev Neurosci
, vol.12
, pp. 284-296
-
-
Di Paolo, G.1
Kim, T.W.2
-
62
-
-
77649211967
-
beta-Amyloid activates presynaptic alpha7 nicotinic acetylcholine receptors reconstituted into a model nerve cell system: Involvement of lipid rafts
-
Khan GM, Tong M, Jhun M, Arora K, Nichols RA. beta-Amyloid activates presynaptic alpha7 nicotinic acetylcholine receptors reconstituted into a model nerve cell system: involvement of lipid rafts. Eur J Neurosci 31: 788-96 (2010).
-
(2010)
Eur J Neurosci
, vol.31
, pp. 788-796
-
-
Khan, G.M.1
Tong, M.2
Jhun, M.3
Arora, K.4
Nichols, R.A.5
-
63
-
-
0035875962
-
Beta-amyloid activates the mitogen-activated protein kinase cascade via hippocampal alpha7 nicotinic acetylcholine receptors: In vitro and in vivo mechanisms related to Alzheimer's disease
-
Dineley KT, Westerman M, Bui D, Bell K, Ashe KH, Sweatt JD. Beta-amyloid activates the mitogen-activated protein kinase cascade via hippocampal alpha7 nicotinic acetylcholine receptors: In vitro and in vivo mechanisms related to Alzheimer's disease. J Neurosci 21: 4125-33 (2001).
-
(2001)
J Neurosci
, vol.21
, pp. 4125-4133
-
-
Dineley, K.T.1
Westerman, M.2
Bui, D.3
Bell, K.4
Ashe, K.H.5
Sweatt, J.D.6
-
64
-
-
0035219699
-
beta-Amyloid(1-42) peptide directly modulates nicotinic receptors in the rat hippocampal slice
-
Pettit DL, Shao Z, Yakel JL. beta-Amyloid(1-42) peptide directly modulates nicotinic receptors in the rat hippocampal slice. J Neurosci 21: RC120 (2001).
-
(2001)
J Neurosci
, vol.21
-
-
Pettit, D.L.1
Shao, Z.2
Yakel, J.L.3
-
65
-
-
0037067717
-
beta-Amyloid peptide activates alpha 7 nicotinic acetylcholine receptors expressed in Xenopus oocytes
-
Dineley KT, Bell KA, Bui D, Sweatt JD. beta-Amyloid peptide activates alpha 7 nicotinic acetylcholine receptors expressed in Xenopus oocytes. J Biol Chem 277: 25056-61 (2002).
-
(2002)
J Biol Chem
, vol.277
, pp. 25056-25061
-
-
Dineley, K.T.1
Bell, K.A.2
Bui, D.3
Sweatt, J.D.4
-
66
-
-
0038496743
-
Modulation of presynaptic store calcium induces release of glutamate and postsynaptic firing
-
Sharma G, Vijayaraghavan S. Modulation of presynaptic store calcium induces release of glutamate and postsynaptic firing. Neuron 38: 929-39 (2003).
-
(2003)
Neuron
, vol.38
, pp. 929-939
-
-
Sharma, G.1
Vijayaraghavan, S.2
-
67
-
-
53749087290
-
Modulation of hippocampus-dependent learning and synaptic plasticity by nicotine
-
Kenney JW, Gould TJ. Modulation of hippocampus-dependent learning and synaptic plasticity by nicotine. Mol Neurobiol 38: 101-21 (2008).
-
(2008)
Mol Neurobiol
, vol.38
, pp. 101-121
-
-
Kenney, J.W.1
Gould, T.J.2
-
68
-
-
65549084830
-
Defining pre-synaptic nicotinic receptors regulated by beta amyloid in mouse cortex and hippocampus with receptor null mutants
-
Mehta TK, Dougherty JJ, Wu J, Choi CH, Khan GM, Nichols RA. Defining pre-synaptic nicotinic receptors regulated by beta amyloid in mouse cortex and hippocampus with receptor null mutants. J Neurochem 109: 1452-8 (2009).
-
(2009)
J Neurochem
, vol.109
, pp. 1452-1458
-
-
Mehta, T.K.1
Dougherty, J.J.2
Wu, J.3
Choi, C.H.4
Khan, G.M.5
Nichols, R.A.6
-
69
-
-
36049007514
-
Dopamine release in prefrontal cortex in response to beta-amyloid activation of alpha7 * nicotinic receptors
-
Wu J, Khan GM, Nichols RA. Dopamine release in prefrontal cortex in response to beta-amyloid activation of alpha7 * nicotinic receptors. Brain Res 1182: 82-9 (2007).
-
(2007)
Brain Res
, vol.1182
, pp. 82-89
-
-
Wu, J.1
Khan, G.M.2
Nichols, R.A.3
-
70
-
-
58149385218
-
Picomolar amyloid-beta positively modulates synaptic plasticity and memory in hippocampus
-
Puzzo D, Privitera L, Leznik E, Fa M, Staniszewski A, Palmeri A, et al. Picomolar amyloid-beta positively modulates synaptic plasticity and memory in hippocampus. J Neurosci 28: 14537-45 (2008).
-
(2008)
J Neurosci
, vol.28
, pp. 14537-14545
-
-
Puzzo, D.1
Privitera, L.2
Leznik, E.3
Fa, M.4
Staniszewski, A.5
Palmeri, A.6
-
71
-
-
0029096914
-
Nicotine enhancement of fast excitatory synaptic transmission in CNS by presynaptic receptors
-
McGehee DS, Heath MJ, Gelber S, Devay P, Role LW. Nicotine enhancement of fast excitatory synaptic transmission in CNS by presynaptic receptors. Science 269: 1692-6 (1995).
-
(1995)
Science
, vol.269
, pp. 1692-1696
-
-
McGehee, D.S.1
Heath, M.J.2
Gelber, S.3
Devay, P.4
Role, L.W.5
-
72
-
-
0035107610
-
Ca(2+) changes induced by different presynaptic nicotinic receptors in separate populations of individual striatal nerve terminals
-
Nayak SV, Dougherty JJ, McIntosh JM, Nichols RA. Ca(2+) changes induced by different presynaptic nicotinic receptors in separate populations of individual striatal nerve terminals. J Neurochem 76: 1860-70 (2001).
-
(2001)
J Neurochem
, vol.76
, pp. 1860-1870
-
-
Nayak, S.V.1
Dougherty, J.J.2
McIntosh, J.M.3
Nichols, R.A.4
-
73
-
-
84856299171
-
Activation of alpha7 nicotinic acetylcholine receptors persistently enhances hippocampal synaptic transmission and prevents Ass-mediated inhibition of LTP in the rat hippocampus
-
Ondrejcak T, Wang Q, Kew JN, Virley DJ, Upton N, Anwyl R, et al. Activation of alpha7 nicotinic acetylcholine receptors persistently enhances hippocampal synaptic transmission and prevents Ass-mediated inhibition of LTP in the rat hippocampus. Eur J Pharmacol 677: 63-70 (2012).
-
(2012)
Eur J Pharmacol
, vol.677
, pp. 63-70
-
-
Ondrejcak, T.1
Wang, Q.2
Kew, J.N.3
Virley, D.J.4
Upton, N.5
Anwyl, R.6
-
74
-
-
21044453723
-
Amyloid beta protein immunotherapy neutralizes Abeta oligomers that disrupt synaptic plasticity in vivo
-
Klyubin I, Walsh DM, Lemere CA, Cullen WK, Shankar GM, Betts V, et al. Amyloid beta protein immunotherapy neutralizes Abeta oligomers that disrupt synaptic plasticity in vivo. Nat Med 11: 556-61 (2005).
-
(2005)
Nat Med
, vol.11
, pp. 556-561
-
-
Klyubin, I.1
Walsh, D.M.2
Lemere, C.A.3
Cullen, W.K.4
Shankar, G.M.5
Betts, V.6
-
75
-
-
80052366846
-
Requirement of alpha7 nicotinic acetylcholine receptors for amyloid beta protein-induced depression of hippocampal long-term potentiation in CA1 region of rats in vivo
-
Li SF, Wu MN, Wang XH, Yuan L, Yang D, Qi JS. Requirement of alpha7 nicotinic acetylcholine receptors for amyloid beta protein-induced depression of hippocampal long-term potentiation in CA1 region of rats in vivo. Synapse 65: 1136-43 (2011).
-
(2011)
Synapse
, vol.65
, pp. 1136-1143
-
-
Li, S.F.1
Wu, M.N.2
Wang, X.H.3
Yuan, L.4
Yang, D.5
Qi, J.S.6
-
76
-
-
75049085215
-
Mechanisms of neuroprotective effects of nicotine and acetylcholinesterase inhibitors: Role of alpha4 and alpha7 receptors in neuroprotection
-
Akaike A, Takada-Takatori Y, Kume T, Izumi Y. Mechanisms of neuroprotective effects of nicotine and acetylcholinesterase inhibitors: role of alpha4 and alpha7 receptors in neuroprotection. J Mol Neurosci 40: 211-6 (2010).
-
(2010)
J Mol Neurosci
, vol.40
, pp. 211-216
-
-
Akaike, A.1
Takada-Takatori, Y.2
Kume, T.3
Izumi, Y.4
-
77
-
-
84863534359
-
Cotinine: A potential new therapeutic agent against Alzheimer's disease
-
Echeverria V, Zeitlin R. Cotinine: a potential new therapeutic agent against Alzheimer's disease. CNS Neurosci Ther 18: 517-23 (2012).
-
(2012)
CNS Neurosci Ther
, vol.18
, pp. 517-523
-
-
Echeverria, V.1
Zeitlin, R.2
-
78
-
-
84860468079
-
alpha7 nicotinic acetylcholine receptors in Alzheimer's disease: Neuroprotective, neurotrophic or both?
-
Hernandez CM, Dineley KT. alpha7 nicotinic acetylcholine receptors in Alzheimer's disease: neuroprotective, neurotrophic or both? Curr Drug Targets 13: 613-22 (2012).
-
(2012)
Curr Drug Targets
, vol.13
, pp. 613-622
-
-
Hernandez, C.M.1
Dineley, K.T.2
-
79
-
-
0035957946
-
alpha 7 nicotinic receptor transduces signals to phosphatidylinositol 3-kinase to block A beta-amyloid-induced neurotoxicity
-
Kihara T, Shimohama S, Sawada H, Honda K, Nakamizo T, Shibasaki H, et al. alpha 7 nicotinic receptor transduces signals to phosphatidylinositol 3-kinase to block A beta-amyloid-induced neurotoxicity. J Biol Chem 276: 13541-6 (2001).
-
(2001)
J Biol Chem
, vol.276
, pp. 13541-13546
-
-
Kihara, T.1
Shimohama, S.2
Sawada, H.3
Honda, K.4
Nakamizo, T.5
Shibasaki, H.6
-
80
-
-
84861074503
-
Neuroprotection by nicotine against colchicine-induced apoptosis is mediated by PI3-kinase--Akt pathways
-
Huang X, Cheng Z, Su Q, Zhu X, Wang Q, Chen R, et al. Neuroprotection by nicotine against colchicine-induced apoptosis is mediated by PI3-kinase--Akt pathways. Int J Neurosci 122: 324-32 (2012).
-
(2012)
Int J Neurosci
, vol.122
, pp. 324-332
-
-
Huang, X.1
Cheng, Z.2
Su, Q.3
Zhu, X.4
Wang, Q.5
Chen, R.6
-
81
-
-
80054811612
-
alpha7 Nicotinic receptor activation reduces beta-amyloid-induced apoptosis by inhibiting caspase-independent death through phosphatidylinositol 3-kinase signaling
-
Yu W, Mechawar N, Krantic S, Quirion R. alpha7 Nicotinic receptor activation reduces beta-amyloid-induced apoptosis by inhibiting caspase-independent death through phosphatidylinositol 3-kinase signaling. J Neurochem 119: 848-58 (2011).
-
(2011)
J Neurochem
, vol.119
, pp. 848-858
-
-
Yu, W.1
Mechawar, N.2
Krantic, S.3
Quirion, R.4
-
82
-
-
4444222410
-
The alpha7 nicotinic acetylcholine receptor-selective antagonist, methyllycaconitine, partially protects against beta-amyloid1-42 toxicity in primary neuron-enriched cultures
-
Martin SE, de Fiebre NE, de Fiebre CM. The alpha7 nicotinic acetylcholine receptor-selective antagonist, methyllycaconitine, partially protects against beta-amyloid1-42 toxicity in primary neuron-enriched cultures. Brain Res 1022: 254-6 (2004).
-
(2004)
Brain Res
, vol.1022
, pp. 254-256
-
-
Martin, S.E.1
de Fiebre, N.E.2
de Fiebre, C.M.3
-
83
-
-
0035889406
-
Relationship between the increased cell surface alpha7 nicotinic receptor expression and neuroprotection induced by several nicotinic receptor agonists
-
Jonnala RR, Buccafusco JJ. Relationship between the increased cell surface alpha7 nicotinic receptor expression and neuroprotection induced by several nicotinic receptor agonists. J Neurosci Res 66: 565-72 (2001).
-
(2001)
J Neurosci Res
, vol.66
, pp. 565-572
-
-
Jonnala, R.R.1
Buccafusco, J.J.2
-
84
-
-
77953287701
-
Nicotine exacerbates tau phosphorylation and cognitive impairment induced by amyloid-beta 25-35 in rats
-
Deng J, Shen C, Wang YJ, Zhang M, Li J, Xu ZQ, et al. Nicotine exacerbates tau phosphorylation and cognitive impairment induced by amyloid-beta 25-35 in rats. Eur J Pharmacol 637: 83-8 (2010).
-
(2010)
Eur J Pharmacol
, vol.637
, pp. 83-88
-
-
Deng, J.1
Shen, C.2
Wang, Y.J.3
Zhang, M.4
Li, J.5
Xu, Z.Q.6
-
85
-
-
14544304591
-
Chronic nicotine administration exacerbates tau pathology in a transgenic model of Alzheimer's disease
-
Oddo S, Caccamo A, Green KN, Liang K, Tran L, Chen Y, et al. Chronic nicotine administration exacerbates tau pathology in a transgenic model of Alzheimer's disease. Proc Natl Acad Sci U S A 102: 3046-51 (2005).
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 3046-3051
-
-
Oddo, S.1
Caccamo, A.2
Green, K.N.3
Liang, K.4
Tran, L.5
Chen, Y.6
-
86
-
-
0037381479
-
Differential physiologic responses of alpha7 nicotinic acetylcholine receptors to beta-amyloid1-40 and betaamyloid1-42
-
Lee DH, Wang HY. Differential physiologic responses of alpha7 nicotinic acetylcholine receptors to beta-amyloid1-40 and betaamyloid1-42. J Neurobiol 55: 25-30 (2003).
-
(2003)
J Neurobiol
, vol.55
, pp. 25-30
-
-
Lee, D.H.1
Wang, H.Y.2
-
87
-
-
69749119522
-
Dissociating beta-amyloid from alpha 7 nicotinic acetylcholine receptor by a novel therapeutic agent, S 24795, normalizes alpha 7 nicotinic acetylcholine and NMDA receptor function in Alzheimer's disease brain
-
Wang HY, Stucky A, Liu J, Shen C, Trocme-Thibierge C, Morain P. Dissociating beta-amyloid from alpha 7 nicotinic acetylcholine receptor by a novel therapeutic agent, S 24795, normalizes alpha 7 nicotinic acetylcholine and NMDA receptor function in Alzheimer's disease brain. J Neurosci 29: 10961-73 (2009).
-
(2009)
J Neurosci
, vol.29
, pp. 10961-10973
-
-
Wang, H.Y.1
Stucky, A.2
Liu, J.3
Shen, C.4
Trocme-Thibierge, C.5
Morain, P.6
-
88
-
-
33645038471
-
A specific amyloid-beta protein assembly in the brain impairs memory
-
Lesne S, Koh MT, Kotilinek L, Kayed R, Glabe CG, Yang A, et al. A specific amyloid-beta protein assembly in the brain impairs memory. Nature 440: 352-7 (2006).
-
(2006)
Nature
, vol.440
, pp. 352-357
-
-
Lesne, S.1
Koh, M.T.2
Kotilinek, L.3
Kayed, R.4
Glabe, C.G.5
Yang, A.6
-
89
-
-
33748960736
-
Neuroprotective effects of galanthamine and tacrine against glutamate neurotoxicity
-
Takada-Takatori Y, Kume T, Sugimoto M, Katsuki H, Niidome T, Sugimoto H, et al. Neuroprotective effects of galanthamine and tacrine against glutamate neurotoxicity. Eur J Pharmacol 549: 19-26 (2006).
-
(2006)
Eur J Pharmacol
, vol.549
, pp. 19-26
-
-
Takada-Takatori, Y.1
Kume, T.2
Sugimoto, M.3
Katsuki, H.4
Niidome, T.5
Sugimoto, H.6
-
90
-
-
1842375103
-
The amyloid beta-protein of Alzheimer's disease increases acetylcholinesterase expression by increasing intracellular calcium in embryonal carcinoma P19 cells
-
Sberna G, Saez-Valero J, Beyreuther K, Masters CL, Small DH. The amyloid beta-protein of Alzheimer's disease increases acetylcholinesterase expression by increasing intracellular calcium in embryonal carcinoma P19 cells. J Neurochem 69: 1177-84 (1997).
-
(1997)
J Neurochem
, vol.69
, pp. 1177-1184
-
-
Sberna, G.1
Saez-Valero, J.2
Beyreuther, K.3
Masters, C.L.4
Small, D.H.5
-
91
-
-
1442348421
-
Alpha7-nicotinic acetylcholine receptors mediate an Abeta(1-42)-induced increase in the level of acetylcholinesterase in primary cortical neurones
-
Fodero LR, Mok SS, Losic D, Martin LL, Aguilar MI, Barrow CJ, et al. Alpha7-nicotinic acetylcholine receptors mediate an Abeta(1-42)-induced increase in the level of acetylcholinesterase in primary cortical neurones. J Neurochem 88: 1186-93 (2004).
-
(2004)
J Neurochem
, vol.88
, pp. 1186-1193
-
-
Fodero, L.R.1
Mok, S.S.2
Losic, D.3
Martin, L.L.4
Aguilar, M.I.5
Barrow, C.J.6
-
92
-
-
34848913464
-
The consequences of reducing expression of the alpha7 nicotinic receptor by RNA interference and of stimulating its activity with an alpha7 agonist in SH-SY5Y cells indicate that this receptor plays a neuroprotective role in connection with the pathogenesis of Alzheimer's disease
-
Qi XL, Nordberg A, Xiu J, Guan ZZ. The consequences of reducing expression of the alpha7 nicotinic receptor by RNA interference and of stimulating its activity with an alpha7 agonist in SH-SY5Y cells indicate that this receptor plays a neuroprotective role in connection with the pathogenesis of Alzheimer's disease. Neurochem Int 51: 377-83 (2007).
-
(2007)
Neurochem Int
, vol.51
, pp. 377-383
-
-
Qi, X.L.1
Nordberg, A.2
Xiu, J.3
Guan, Z.Z.4
-
93
-
-
77249153190
-
Loss of alpha7 nicotinic receptors enhances beta-amyloid oligomer accumulation, exacerbating early-stage cognitive decline and septohippocampal pathology in a mouse model of Alzheimer's disease
-
Hernandez CM, Kayed R, Zheng H, Sweatt JD, Dineley KT. Loss of alpha7 nicotinic receptors enhances beta-amyloid oligomer accumulation, exacerbating early-stage cognitive decline and septohippocampal pathology in a mouse model of Alzheimer's disease. J Neurosci 30: 2442-53 (2010).
-
(2010)
J Neurosci
, vol.30
, pp. 2442-2453
-
-
Hernandez, C.M.1
Kayed, R.2
Zheng, H.3
Sweatt, J.D.4
Dineley, K.T.5
-
94
-
-
62949084265
-
Selective alpha7 nicotinic acetylcholine receptor activation regulates glycogen synthase kinase3beta and decreases tau phosphorylation in vivo
-
Bitner RS, Nikkel AL, Markosyan S, Otte S, Puttfarcken P, Gopalakrishnan M. Selective alpha7 nicotinic acetylcholine receptor activation regulates glycogen synthase kinase3beta and decreases tau phosphorylation in vivo. Brain Res 1265: 65-74 (2009).
-
(2009)
Brain Res
, vol.1265
, pp. 65-74
-
-
Bitner, R.S.1
Nikkel, A.L.2
Markosyan, S.3
Otte, S.4
Puttfarcken, P.5
Gopalakrishnan, M.6
-
95
-
-
0345434817
-
Regional distribution of nicotinic receptor subunit mRNAs in human brain: Comparison between Alzheimer and normal brain
-
Hellstrom-Lindahl E, Mousavi M, Zhang X, Ravid R, Nordberg A. Regional distribution of nicotinic receptor subunit mRNAs in human brain: comparison between Alzheimer and normal brain. Brain Res Mol Brain Res 66: 94-103 (1999).
-
(1999)
Brain Res Mol Brain Res
, vol.66
, pp. 94-103
-
-
Hellstrom-Lindahl, E.1
Mousavi, M.2
Zhang, X.3
Ravid, R.4
Nordberg, A.5
-
96
-
-
20644443926
-
Increased alpha 7 nicotinic acetylcholine receptor protein levels in Alzheimer's disease patients
-
Chu LW, Ma ES, Lam KK, Chan MF, Lee DH. Increased alpha 7 nicotinic acetylcholine receptor protein levels in Alzheimer's disease patients. Dement Geriatr Cogn Disord 19: 106-12 (2005).
-
(2005)
Dement Geriatr Cogn Disord
, vol.19
, pp. 106-112
-
-
Chu, L.W.1
Ma, E.S.2
Lam, K.K.3
Chan, M.F.4
Lee, D.H.5
-
97
-
-
0036318339
-
Selective nicotinic receptor consequences in APP(SWE) transgenic mice
-
Bednar I, Paterson D, Marutle A, Pham TM, Svedberg M, Hellstrom-Lindahl E, et al. Selective nicotinic receptor consequences in APP(SWE) transgenic mice. Mol Cell Neurosci 20: 354-65 (2002).
-
(2002)
Mol Cell Neurosci
, vol.20
, pp. 354-365
-
-
Bednar, I.1
Paterson, D.2
Marutle, A.3
Pham, T.M.4
Svedberg, M.5
Hellstrom-Lindahl, E.6
-
98
-
-
2542481651
-
Contribution of glial cells to the development of amyloid plaques in Alzheimer's disease
-
Nagele RG, Wegiel J, Venkataraman V, Imaki H, Wang KC. Contribution of glial cells to the development of amyloid plaques in Alzheimer's disease. Neurobiol Aging 25: 663-74 (2004).
-
(2004)
Neurobiol Aging
, vol.25
, pp. 663-674
-
-
Nagele, R.G.1
Wegiel, J.2
Venkataraman, V.3
Imaki, H.4
Wang, K.C.5
-
99
-
-
66249133352
-
Cortical alpha7 nicotinic acetylcholine receptor and beta-amyloid levels in early Alzheimer disease
-
Ikonomovic MD, Wecker L, Abrahamson EE, Wuu J, Counts SE, Ginsberg SD, et al. Cortical alpha7 nicotinic acetylcholine receptor and beta-amyloid levels in early Alzheimer disease. Arch Neurol 66: 646-51 (2009).
-
(2009)
Arch Neurol
, vol.66
, pp. 646-651
-
-
Ikonomovic, M.D.1
Wecker, L.2
Abrahamson, E.E.3
Wuu, J.4
Counts, S.E.5
Ginsberg, S.D.6
-
100
-
-
0036178441
-
Molecular psychology: Roles for the ERK MAP kinase cascade in memory
-
Adams JP, Sweatt JD. Molecular psychology: roles for the ERK MAP kinase cascade in memory. Annu Rev Pharmacol Toxicol 42: 135-63 (2002).
-
(2002)
Annu Rev Pharmacol Toxicol
, vol.42
, pp. 135-163
-
-
Adams, J.P.1
Sweatt, J.D.2
-
101
-
-
1342289413
-
MAPK cascade signalling and synaptic plasticity
-
Thomas GM, Huganir RL. MAPK cascade signalling and synaptic plasticity. Nat Rev Neurosci 5: 173-83 (2004).
-
(2004)
Nat Rev Neurosci
, vol.5
, pp. 173-183
-
-
Thomas, G.M.1
Huganir, R.L.2
-
102
-
-
70349952431
-
Oligomeric aggregates of amyloid beta peptide 1-42 activate ERK/MAPK in SH-SY5Y cells via the alpha7 nicotinic receptor
-
Young KF, Pasternak SH, Rylett RJ. Oligomeric aggregates of amyloid beta peptide 1-42 activate ERK/MAPK in SH-SY5Y cells via the alpha7 nicotinic receptor. Neurochem Int 55: 796-801 (2009).
-
(2009)
Neurochem Int
, vol.55
, pp. 796-801
-
-
Young, K.F.1
Pasternak, S.H.2
Rylett, R.J.3
-
103
-
-
43849088152
-
Abeta(1-42) modulation of Akt phosphorylation via alpha7 nAChR and NMDA receptors
-
Abbott JJ, Howlett DR, Francis PT, Williams RJ. Abeta(1-42) modulation of Akt phosphorylation via alpha7 nAChR and NMDA receptors. Neurobiol Aging 29: 992-1001 (2008).
-
(2008)
Neurobiol Aging
, vol.29
, pp. 992-1001
-
-
Abbott, J.J.1
Howlett, D.R.2
Francis, P.T.3
Williams, R.J.4
-
104
-
-
23044445669
-
Regulation of NMDA receptor trafficking by amyloid-beta
-
Snyder EM, Nong Y, Almeida CG, Paul S, Moran T, Choi EY, et al. Regulation of NMDA receptor trafficking by amyloid-beta. Nat Neurosci 8: 1051-8 (2005).
-
(2005)
Nat Neurosci
, vol.8
, pp. 1051-1058
-
-
Snyder, E.M.1
Nong, Y.2
Almeida, C.G.3
Paul, S.4
Moran, T.5
Choi, E.Y.6
-
105
-
-
2542509442
-
Increased levels of tau protein in SH-SY5Y cells after treatment with cholinesterase inhibitors and nicotinic agonists
-
Hellstrom-Lindahl E, Moore H, Nordberg A. Increased levels of tau protein in SH-SY5Y cells after treatment with cholinesterase inhibitors and nicotinic agonists. J Neurochem 74: 777-84 (2000).
-
(2000)
J Neurochem
, vol.74
, pp. 777-784
-
-
Hellstrom-Lindahl, E.1
Moore, H.2
Nordberg, A.3
-
106
-
-
84863963797
-
Reducing amyloid-related Alzheimer's disease pathogenesis by a small molecule targeting filamin A
-
Wang HY, Bakshi K, Frankfurt M, Stucky A, Goberdhan M, Shah SM, et al. Reducing amyloid-related Alzheimer's disease pathogenesis by a small molecule targeting filamin A. J Neurosci 32: 9773-84 (2012).
-
(2012)
J Neurosci
, vol.32
, pp. 9773-9784
-
-
Wang, H.Y.1
Bakshi, K.2
Frankfurt, M.3
Stucky, A.4
Goberdhan, M.5
Shah, S.M.6
-
107
-
-
0343570105
-
Modulation of beta-amyloid precursor protein processing and tau phosphorylation by acetylcholine receptors
-
Hellstrom-Lindahl E. Modulation of beta-amyloid precursor protein processing and tau phosphorylation by acetylcholine receptors. Eur J Pharmacol 393: 255-63 (2000).
-
(2000)
Eur J Pharmacol
, vol.393
, pp. 255-263
-
-
Hellstrom-Lindahl, E.1
-
108
-
-
0030773730
-
Does smoking protect from Alzheimer's disease? Alzheimer-type changes in 301 unselected brains from patients with known smoking history
-
Ulrich J, Johannson-Locher G, Seiler WO, Stahelin HB. Does smoking protect from Alzheimer's disease? Alzheimer-type changes in 301 unselected brains from patients with known smoking history. Acta Neuropathol 94: 450-4 (1997).
-
(1997)
Acta Neuropathol
, vol.94
, pp. 450-454
-
-
Ulrich, J.1
Johannson-Locher, G.2
Seiler, W.O.3
Stahelin, H.B.4
-
109
-
-
84859557082
-
Smoking, nicotine and dementia
-
Grayson L, Thomas AJ. Smoking, nicotine and dementia. Maturitas 72: 4-5 (2012).
-
(2012)
Maturitas
, vol.72
, pp. 4-5
-
-
Grayson, L.1
Thomas, A.J.2
-
110
-
-
0028986916
-
beta-amyloid fibrils induce tau phosphorylation and loss of microtubule binding
-
Busciglio J, Lorenzo A, Yeh J, Yankner BA. beta-amyloid fibrils induce tau phosphorylation and loss of microtubule binding. Neuron 14: 879-88 (1995).
-
(1995)
Neuron
, vol.14
, pp. 879-888
-
-
Busciglio, J.1
Lorenzo, A.2
Yeh, J.3
Yankner, B.A.4
-
111
-
-
40649095625
-
Network dysfunction in Alzheimer's disease: Does synaptic scaling drive disease progression?
-
Small DH. Network dysfunction in Alzheimer's disease: does synaptic scaling drive disease progression? Trends Mol Med 14: 103-8 (2008).
-
(2008)
Trends Mol Med
, vol.14
, pp. 103-108
-
-
Small, D.H.1
-
112
-
-
0034535535
-
Cell death or synaptic loss in Alzheimer disease
-
Terry RD. Cell death or synaptic loss in Alzheimer disease. J Neuropathol Exp Neurol 59: 1118-9 (2000).
-
(2000)
J Neuropathol Exp Neurol
, vol.59
, pp. 1118-1119
-
-
Terry, R.D.1
-
113
-
-
0742323527
-
Homeostatic plasticity in the developing nervous system
-
Turrigiano GG, Nelson SB. Homeostatic plasticity in the developing nervous system. Nat Rev Neurosci 5: 97-107 (2004).
-
(2004)
Nat Rev Neurosci
, vol.5
, pp. 97-107
-
-
Turrigiano, G.G.1
Nelson, S.B.2
-
114
-
-
34548264782
-
Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's disease
-
Palop JJ, Chin J, Roberson ED, Wang J, Thwin MT, Bien-Ly N, et al. Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's disease. Neuron 55: 697-711 (2007).
-
(2007)
Neuron
, vol.55
, pp. 697-711
-
-
Palop, J.J.1
Chin, J.2
Roberson, E.D.3
Wang, J.4
Thwin, M.T.5
Bien-Ly, N.6
-
115
-
-
77954132249
-
Amyloid-beta-induced neuronal dysfunction in Alzheimer's disease: From synapses toward neural networks
-
Palop JJ, Mucke L. Amyloid-beta-induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks. Nat Neurosci 13: 812-8 (2010).
-
(2010)
Nat Neurosci
, vol.13
, pp. 812-818
-
-
Palop, J.J.1
Mucke, L.2
-
116
-
-
1942436820
-
Do acetylcholinesterase inhibitors boost synaptic scaling in Alzheimer's disease?
-
Small DH. Do acetylcholinesterase inhibitors boost synaptic scaling in Alzheimer's disease? Trends Neurosci 27: 245-9 (2004).
-
(2004)
Trends Neurosci
, vol.27
, pp. 245-249
-
-
Small, D.H.1
-
117
-
-
0036156958
-
Upregulation of choline acetyltransferase activity in hippocampus and frontal cortex of elderly subjects with mild cognitive impairment
-
DeKosky ST, Ikonomovic MD, Styren SD, Beckett L, Wisniewski S, Bennett DA, et al. Upregulation of choline acetyltransferase activity in hippocampus and frontal cortex of elderly subjects with mild cognitive impairment. Ann Neurol 51: 145-55 (2002).
-
(2002)
Ann Neurol
, vol.51
, pp. 145-155
-
-
Dekosky, S.T.1
Ikonomovic, M.D.2
Styren, S.D.3
Beckett, L.4
Wisniewski, S.5
Bennett, D.A.6
-
118
-
-
0037151046
-
Accelerated plaque accumulation, associative learning deficits, and upregulation of alpha 7 nicotinic receptor protein in transgenic mice co-expressing mutant human presenilin 1 and amyloid precursor proteins
-
Dineley KT, Xia X, Bui D, Sweatt JD, Zheng H. Accelerated plaque accumulation, associative learning deficits, and upregulation of alpha 7 nicotinic receptor protein in transgenic mice co-expressing mutant human presenilin 1 and amyloid precursor proteins. J Biol Chem 277: 22768-80 (2002).
-
(2002)
J Biol Chem
, vol.277
, pp. 22768-22780
-
-
Dineley, K.T.1
Xia, X.2
Bui, D.3
Sweatt, J.D.4
Zheng, H.5
-
119
-
-
0036312401
-
Altered glycosylation of acetylcholinesterase in APP (SW) Tg2576 transgenic mice occurs prior to amyloid plaque deposition
-
Fodero LR, Saez-Valero J, McLean CA, Martins RN, Beyreuther K, Masters CL, et al. Altered glycosylation of acetylcholinesterase in APP (SW) Tg2576 transgenic mice occurs prior to amyloid plaque deposition. J Neurochem 81: 441-8 (2002).
-
(2002)
J Neurochem
, vol.81
, pp. 441-448
-
-
Fodero, L.R.1
Saez-Valero, J.2
McLean, C.A.3
Martins, R.N.4
Beyreuther, K.5
Masters, C.L.6
-
120
-
-
34547653708
-
Acute inhibition of calcineurin restores associative learning and memory in Tg2576 APP transgenic mice
-
Dineley KT, Hogan D, Zhang WR, Taglialatela G. Acute inhibition of calcineurin restores associative learning and memory in Tg2576 APP transgenic mice. Neurobiol Learn Mem 88: 217-24 (2007).
-
(2007)
Neurobiol Learn Mem
, vol.88
, pp. 217-224
-
-
Dineley, K.T.1
Hogan, D.2
Zhang, W.R.3
Taglialatela, G.4
-
121
-
-
67650484613
-
Deletion of the alpha 7 nicotinic acetylcholine receptor gene improves cognitive deficits and synaptic pathology in a mouse model of Alzheimer's disease
-
Dziewczapolski G, Glogowski CM, Masliah E, Heinemann SF. Deletion of the alpha 7 nicotinic acetylcholine receptor gene improves cognitive deficits and synaptic pathology in a mouse model of Alzheimer's disease. J Neurosci 29: 8805-15 (2009).
-
(2009)
J Neurosci
, vol.29
, pp. 8805-8815
-
-
Dziewczapolski, G.1
Glogowski, C.M.2
Masliah, E.3
Heinemann, S.F.4
-
122
-
-
62649147319
-
Intermediateand long-term recognition memory deficits in Tg2576 mice are reversed with acute calcineurin inhibition
-
Taglialatela G, Hogan D, Zhang WR, Dineley KT. Intermediateand long-term recognition memory deficits in Tg2576 mice are reversed with acute calcineurin inhibition. Behav Brain Res 200: 95-9 (2009).
-
(2009)
Behav Brain Res
, vol.200
, pp. 95-99
-
-
Taglialatela, G.1
Hogan, D.2
Zhang, W.R.3
Dineley, K.T.4
-
123
-
-
0028172886
-
Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red
-
Lorenzo A, Yankner BA. Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red. Proc Natl Acad Sci U S A 91: 12243-7 (1994).
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 12243-12247
-
-
Lorenzo, A.1
Yankner, B.A.2
-
124
-
-
0027257708
-
Apoptosis is induced by beta-amyloid in cultured central nervous system neurons
-
Loo DT, Copani A, Pike CJ, Whittemore ER, Walencewicz AJ, Cotman CW. Apoptosis is induced by beta-amyloid in cultured central nervous system neurons. Proc Natl Acad Sci U S A 90: 7951-5 (1993).
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 7951-7955
-
-
Loo, D.T.1
Copani, A.2
Pike, C.J.3
Whittemore, E.R.4
Walencewicz, A.J.5
Cotman, C.W.6
-
125
-
-
34248190279
-
A beta oligomers-a decade of discovery
-
Walsh DM, Selkoe DJ. A beta oligomers-a decade of discovery. J Neurochem 101: 1172-84 (2007).
-
(2007)
J Neurochem
, vol.101
, pp. 1172-1184
-
-
Walsh, D.M.1
Selkoe, D.J.2
-
126
-
-
16644379264
-
Natural oligomers of the amyloid-beta protein specifically disrupt cognitive function
-
Cleary JP, Walsh DM, Hofmeister JJ, Shankar GM, Kuskowski MA, Selkoe DJ, et al. Natural oligomers of the amyloid-beta protein specifically disrupt cognitive function. Nat Neurosci 8: 79-84 (2005).
-
(2005)
Nat Neurosci
, vol.8
, pp. 79-84
-
-
Cleary, J.P.1
Walsh, D.M.2
Hofmeister, J.J.3
Shankar, G.M.4
Kuskowski, M.A.5
Selkoe, D.J.6
-
127
-
-
33645220400
-
Targeting amyloid-beta peptide (Abeta) oligomers by passive immunization with a conformation-selective monoclonal antibody improves learning and memory in Abeta precursor protein (APP) transgenic mice
-
Lee EB, Leng LZ, Zhang B, Kwong L, Trojanowski JQ, Abel T, et al. Targeting amyloid-beta peptide (Abeta) oligomers by passive immunization with a conformation-selective monoclonal antibody improves learning and memory in Abeta precursor protein (APP) transgenic mice. J Biol Chem 281: 4292-9 (2006).
-
(2006)
J Biol Chem
, vol.281
, pp. 4292-4299
-
-
Lee, E.B.1
Leng, L.Z.2
Zhang, B.3
Kwong, L.4
Trojanowski, J.Q.5
Abel, T.6
-
128
-
-
0042838303
-
Alzheimer's disease-affected brain: Presence of oligomeric A beta ligands (ADDLs) suggests a molecular basis for reversible memory loss
-
Gong Y, Chang L, Viola KL, Lacor PN, Lambert MP, Finch CE, et al. Alzheimer's disease-affected brain: presence of oligomeric A beta ligands (ADDLs) suggests a molecular basis for reversible memory loss. Proc Natl Acad Sci U S A 100: 10417-22 (2003).
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 10417-10422
-
-
Gong, Y.1
Chang, L.2
Viola, K.L.3
Lacor, P.N.4
Lambert, M.P.5
Finch, C.E.6
-
129
-
-
78149361157
-
How do Soluble Oligomers of Amyloid beta-protein Impair Hippocampal Synaptic Plasticity?
-
Li S, Shankar GM, Selkoe DJ. How do Soluble Oligomers of Amyloid beta-protein Impair Hippocampal Synaptic Plasticity? Front Cell Neurosci 4: 5 (2010).
-
(2010)
Front Cell Neurosci
, vol.4
, pp. 5
-
-
Li, S.1
Shankar, G.M.2
Selkoe, D.J.3
-
130
-
-
79951567728
-
Functional interactions of fibrillar and oligomeric amyloid-beta with alpha7 nicotinic receptors in Alzheimer's disease
-
Lilja AM, Porras O, Storelli E, Nordberg A, Marutle A. Functional interactions of fibrillar and oligomeric amyloid-beta with alpha7 nicotinic receptors in Alzheimer's disease. J Alzheimers Dis 23: 335-47 (2011).
-
(2011)
J Alzheimers Dis
, vol.23
, pp. 335-347
-
-
Lilja, A.M.1
Porras, O.2
Storelli, E.3
Nordberg, A.4
Marutle, A.5
-
131
-
-
80052033738
-
Research update: Alpha7 nicotinic acetylcholine receptor mechanisms in Alzheimer's disease
-
Parri HR, Hernandez CM, Dineley KT. Research update: Alpha7 nicotinic acetylcholine receptor mechanisms in Alzheimer's disease. Biochem Pharmacol 82: 931-42 (2011).
-
(2011)
Biochem Pharmacol
, vol.82
, pp. 931-942
-
-
Parri, H.R.1
Hernandez, C.M.2
Dineley, K.T.3
-
132
-
-
30744443800
-
alpha7 Nicotinic acetylcholine receptor as a target to rescue deficit in hippocampal LTP induction in beta-amyloid infused rats
-
Chen L, Yamada K, Nabeshima T, Sokabe M. alpha7 Nicotinic acetylcholine receptor as a target to rescue deficit in hippocampal LTP induction in beta-amyloid infused rats. Neuropharmacology 50: 254-68 (2006).
-
(2006)
Neuropharmacology
, vol.50
, pp. 254-268
-
-
Chen, L.1
Yamada, K.2
Nabeshima, T.3
Sokabe, M.4
-
133
-
-
79955474315
-
Endogenous amyloid-beta is necessary for hippocampal synaptic plasticity and memory
-
Puzzo D, Privitera L, Fa M, Staniszewski A, Hashimoto G, Aziz F, et al. Endogenous amyloid-beta is necessary for hippocampal synaptic plasticity and memory. Ann Neurol 69: 819-30 (2011).
-
(2011)
Ann Neurol
, vol.69
, pp. 819-830
-
-
Puzzo, D.1
Privitera, L.2
Fa, M.3
Staniszewski, A.4
Hashimoto, G.5
Aziz, F.6
-
134
-
-
0031410384
-
Choline is a selective agonist of alpha7 nicotinic acetylcholine receptors in the rat brain neurons
-
Alkondon M, Pereira EF, Cortes WS, Maelicke A, Albuquerque EX. Choline is a selective agonist of alpha7 nicotinic acetylcholine receptors in the rat brain neurons. Eur J Neurosci 9: 2734-42 (1997).
-
(1997)
Eur J Neurosci
, vol.9
, pp. 2734-2742
-
-
Alkondon, M.1
Pereira, E.F.2
Cortes, W.S.3
Maelicke, A.4
Albuquerque, E.X.5
-
135
-
-
0030576581
-
An evaluation of neuronal nicotinic acetylcholine receptor activation by quaternary nitrogen compounds indicates that choline is selective for the alpha 7 subtype
-
Papke RL, Bencherif M, Lippiello P. An evaluation of neuronal nicotinic acetylcholine receptor activation by quaternary nitrogen compounds indicates that choline is selective for the alpha 7 subtype. Neurosci Lett 213: 201-4 (1996).
-
(1996)
Neurosci Lett
, vol.213
, pp. 201-204
-
-
Papke, R.L.1
Bencherif, M.2
Lippiello, P.3
-
136
-
-
27744573850
-
Chronic treatment with amyloid beta(1-42) inhibits non-cholinergic highaffinity choline transport in NG108-15 cells through protein kinase C signaling
-
Novakova J, Mikasova L, Machova E, Lisa V, Dolezal V. Chronic treatment with amyloid beta(1-42) inhibits non-cholinergic highaffinity choline transport in NG108-15 cells through protein kinase C signaling. Brain Res 1062: 101-10 (2005).
-
(2005)
Brain Res
, vol.1062
, pp. 101-110
-
-
Novakova, J.1
Mikasova, L.2
Machova, E.3
Lisa, V.4
Dolezal, V.5
-
137
-
-
35348889638
-
Amyolid precursor protein mediates presynaptic localization and activity of the high-affinity choline transporter
-
Wang B, Yang L, Wang Z, Zheng H. Amyolid precursor protein mediates presynaptic localization and activity of the high-affinity choline transporter. Proc Natl Acad Sci U S A 104: 14140-5 (2007).
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 14140-14145
-
-
Wang, B.1
Yang, L.2
Wang, Z.3
Zheng, H.4
-
138
-
-
52049104649
-
Alpha7 nicotinic acetylcholine receptor expression by vascular smooth muscle cells facilitates the deposition of Abeta peptides and promotes cerebrovascular amyloid angiopathy
-
Clifford PM, Siu G, Kosciuk M, Levin EC, Venkataraman V, D'Andrea MR, et al. Alpha7 nicotinic acetylcholine receptor expression by vascular smooth muscle cells facilitates the deposition of Abeta peptides and promotes cerebrovascular amyloid angiopathy. Brain Res 1234: 158-71 (2008).
-
(2008)
Brain Res
, vol.1234
, pp. 158-171
-
-
Clifford, P.M.1
Siu, G.2
Kosciuk, M.3
Levin, E.C.4
Venkataraman, V.5
D'Andrea, M.R.6
-
139
-
-
0037440372
-
Alzheimer's disease is associated with a selective increase in alpha7 nicotinic acetylcholine receptor immunoreactivity in astrocytes
-
Teaktong T, Graham A, Court J, Perry R, Jaros E, Johnson M, et al. Alzheimer's disease is associated with a selective increase in alpha7 nicotinic acetylcholine receptor immunoreactivity in astrocytes. Glia 41: 207-11 (2003).
-
(2003)
Glia
, vol.41
, pp. 207-211
-
-
Teaktong, T.1
Graham, A.2
Court, J.3
Perry, R.4
Jaros, E.5
Johnson, M.6
-
140
-
-
4744354513
-
Nicotinic acetylcholine receptor immunohistochemistry in Alzheimer's disease and dementia with Lewy bodies: Differential neuronal and astroglial pathology
-
Teaktong T, Graham AJ, Court JA, Perry RH, Jaros E, Johnson M, et al. Nicotinic acetylcholine receptor immunohistochemistry in Alzheimer's disease and dementia with Lewy bodies: differential neuronal and astroglial pathology. J Neurol Sci 225: 39-49 (2004).
-
(2004)
J Neurol Sci
, vol.225
, pp. 39-49
-
-
Teaktong, T.1
Graham, A.J.2
Court, J.A.3
Perry, R.H.4
Jaros, E.5
Johnson, M.6
-
141
-
-
13444280311
-
High selective expression of alpha7 nicotinic receptors on astrocytes in the brains of patients with sporadic Alzheimer's disease and patients carrying Swedish APP 670/671 mutation: A possible association with neuritic plaques
-
Yu WF, Guan ZZ, Bogdanovic N, Nordberg A. High selective expression of alpha7 nicotinic receptors on astrocytes in the brains of patients with sporadic Alzheimer's disease and patients carrying Swedish APP 670/671 mutation: a possible association with neuritic plaques. Exp Neurol 192: 215-25 (2005).
-
(2005)
Exp Neurol
, vol.192
, pp. 215-225
-
-
Yu, W.F.1
Guan, Z.Z.2
Bogdanovic, N.3
Nordberg, A.4
-
142
-
-
21744455896
-
Expression of nicotinic receptors on primary cultures of rat astrocytes and up-regulation of the alpha7, alpha4 and beta2 subunits in response to nanomolar concentrations of the beta-amyloid peptide(1-42)
-
Xiu J, Nordberg A, Zhang JT, Guan ZZ. Expression of nicotinic receptors on primary cultures of rat astrocytes and up-regulation of the alpha7, alpha4 and beta2 subunits in response to nanomolar concentrations of the beta-amyloid peptide(1-42). Neurochem Int 47: 281-90 (2005).
-
(2005)
Neurochem Int
, vol.47
, pp. 281-290
-
-
Xiu, J.1
Nordberg, A.2
Zhang, J.T.3
Guan, Z.Z.4
-
143
-
-
0037427384
-
Astrocytes accumulate A beta 42 and give rise to astrocytic amyloid plaques in Alzheimer disease brains
-
Nagele RG, D'Andrea MR, Lee H, Venkataraman V, Wang HY. Astrocytes accumulate A beta 42 and give rise to astrocytic amyloid plaques in Alzheimer disease brains. Brain Res 971: 197-209 (2003).
-
(2003)
Brain Res
, vol.971
, pp. 197-209
-
-
Nagele, R.G.1
D'Andrea, M.R.2
Lee, H.3
Venkataraman, V.4
Wang, H.Y.5
-
144
-
-
79955727727
-
The cholinergic system in aging and neuronal degeneration
-
Schliebs R, Arendt T. The cholinergic system in aging and neuronal degeneration. Behav Brain Res 221: 555-63 (2011).
-
(2011)
Behav Brain Res
, vol.221
, pp. 555-563
-
-
Schliebs, R.1
Arendt, T.2
-
145
-
-
34548677767
-
Allosteric modulation of nicotinic acetylcholine receptors
-
Bertrand D, Gopalakrishnan M. Allosteric modulation of nicotinic acetylcholine receptors. Biochem Pharmacol 74: 1155-63 (2007).
-
(2007)
Biochem Pharmacol
, vol.74
, pp. 1155-1163
-
-
Bertrand, D.1
Gopalakrishnan, M.2
-
146
-
-
80052026910
-
Positive allosteric modulators as an approach to nicotinic acetylcholine receptor-targeted therapeutics: Advantages and limitations
-
Williams DK, Wang J, Papke RL. Positive allosteric modulators as an approach to nicotinic acetylcholine receptor-targeted therapeutics: advantages and limitations. Biochem Pharmacol 82: 915-30 (2011).
-
(2011)
Biochem Pharmacol
, vol.82
, pp. 915-930
-
-
Williams, D.K.1
Wang, J.2
Papke, R.L.3
-
147
-
-
63849213473
-
Nicotinic acetylcholine receptor signalling: Roles in Alzheimer's disease and amyloid neuroprotection
-
Buckingham SD, Jones AK, Brown LA, Sattelle DB. Nicotinic acetylcholine receptor signalling: roles in Alzheimer's disease and amyloid neuroprotection. Pharmacol Rev 61: 39-61 (2009).
-
(2009)
Pharmacol Rev
, vol.61
, pp. 39-61
-
-
Buckingham, S.D.1
Jones, A.K.2
Brown, L.A.3
Sattelle, D.B.4
-
148
-
-
59649098711
-
Desensitization of nicotinic acetylcholine receptors as a strategy for drug development
-
Buccafusco JJ, Beach JW, Terry AV, Jr. Desensitization of nicotinic acetylcholine receptors as a strategy for drug development. J Pharmacol Exp Ther 328: 364-70 (2009).
-
(2009)
J Pharmacol Exp Ther
, vol.328
, pp. 364-370
-
-
Buccafusco, J.J.1
Beach, J.W.2
Terry Jr., A.V.3
-
149
-
-
0038814240
-
Nicotinic receptors differentially regulate N-methyl-D-aspartate damage in acute hippocampal slices
-
Ferchmin PA, Perez D, Eterovic VA, de Vellis J. Nicotinic receptors differentially regulate N-methyl-D-aspartate damage in acute hippocampal slices. J Pharmacol Exp Ther 305: 1071-8 (2003).
-
(2003)
J Pharmacol Exp Ther
, vol.305
, pp. 1071-1078
-
-
Ferchmin, P.A.1
Perez, D.2
Eterovic, V.A.3
de Vellis, J.4
-
150
-
-
0034595443
-
Inactivation of alpha7 ACh receptors and activation of non-alpha7 ACh receptors both contribute to long term potentiation induction in the hippocampal CA1 region
-
Fujii S, Ji Z, Sumikawa K. Inactivation of alpha7 ACh receptors and activation of non-alpha7 ACh receptors both contribute to long term potentiation induction in the hippocampal CA1 region. Neurosci Lett 286: 134-8 (2000).
-
(2000)
Neurosci Lett
, vol.286
, pp. 134-138
-
-
Fujii, S.1
Ji, Z.2
Sumikawa, K.3
-
151
-
-
34248177330
-
High content screen microscopy analysis of A beta 1-42-induced neurite outgrowth reduction in rat primary cortical neurons: Neuroprotective effects of alpha 7 neuronal nicotinic acetylcholine receptor ligands
-
Hu M, Schurdak ME, Puttfarcken PS, El Kouhen R, Gopalakrishnan M, Li J. High content screen microscopy analysis of A beta 1-42-induced neurite outgrowth reduction in rat primary cortical neurons: neuroprotective effects of alpha 7 neuronal nicotinic acetylcholine receptor ligands. Brain Res 1151: 227-35 (2007).
-
(2007)
Brain Res
, vol.1151
, pp. 227-235
-
-
Hu, M.1
Schurdak, M.E.2
Puttfarcken, P.S.3
El Kouhen, R.4
Gopalakrishnan, M.5
Li, J.6
-
152
-
-
60949111629
-
Nicotinic receptor agonists and antagonists increase sAPPalpha secretion and decrease Abeta levels in vitro
-
Mousavi M, Hellstrom-Lindahl E. Nicotinic receptor agonists and antagonists increase sAPPalpha secretion and decrease Abeta levels in vitro. Neurochem Int 54: 237-44 (2009).
-
(2009)
Neurochem Int
, vol.54
, pp. 237-244
-
-
Mousavi, M.1
Hellstrom-Lindahl, E.2
-
153
-
-
0036891571
-
Desensitization of neuronal nicotinic receptors
-
Quick MW, Lester RA. Desensitization of neuronal nicotinic receptors. J Neurobiol 53: 457-78 (2002).
-
(2002)
J Neurobiol
, vol.53
, pp. 457-478
-
-
Quick, M.W.1
Lester, R.A.2
-
154
-
-
76849083911
-
S 24795 limits beta-amyloid-alpha7 nicotinic receptor interaction and reduces Alzheimer's disease-like pathologies
-
Wang HY, Bakshi K, Shen C, Frankfurt M, Trocme-Thibierge C, Morain P. S 24795 limits beta-amyloid-alpha7 nicotinic receptor interaction and reduces Alzheimer's disease-like pathologies. Biol Psychiatry 67: 522-30 (2010).
-
(2010)
Biol Psychiatry
, vol.67
, pp. 522-530
-
-
Wang, H.Y.1
Bakshi, K.2
Shen, C.3
Frankfurt, M.4
Trocme-Thibierge, C.5
Morain, P.6
-
156
-
-
33751309819
-
Cholinesterase inhibitor blockade and its prevention by statins of sympathetic alpha7-nAChR-mediated cerebral nitrergic neurogenic vasodilation
-
Mozayan M, Chen MF, Si M, Chen PY, Premkumar LS, Lee TJ. Cholinesterase inhibitor blockade and its prevention by statins of sympathetic alpha7-nAChR-mediated cerebral nitrergic neurogenic vasodilation. J Cereb Blood Flow Metab 26: 1562-76 (2006).
-
(2006)
J Cereb Blood Flow Metab
, vol.26
, pp. 1562-1576
-
-
Mozayan, M.1
Chen, M.F.2
Si, M.3
Chen, P.Y.4
Premkumar, L.S.5
Lee, T.J.6
-
157
-
-
34548396785
-
Statins prevent cholinesterase inhibitor blockade of sympathetic alpha7-nAChR-mediated currents in rat superior cervical ganglion neurons
-
Mozayan M, Lee TJ. Statins prevent cholinesterase inhibitor blockade of sympathetic alpha7-nAChR-mediated currents in rat superior cervical ganglion neurons. Am J Physiol Heart Circ Physiol 293: H1737-44 (2007).
-
(2007)
Am J Physiol Heart Circ Physiol
, vol.293
-
-
Mozayan, M.1
Lee, T.J.2
-
158
-
-
84868087867
-
Methylene Blue Inhibits the Function of alpha7-Nicotinic Acetylcholine Receptors
-
Al Mansouri AS, Lorke DE, Nurulain SM, Ashor A, Keun-Hang SY, Petroianu G, et al. Methylene Blue Inhibits the Function of alpha7-Nicotinic Acetylcholine Receptors. CNS Neurol Disord Drug Targets 11: 791-800.
-
CNS Neurol Disord Drug Targets
, vol.11
, pp. 791-800
-
-
Al Mansouri, A.S.1
Lorke, D.E.2
Nurulain, S.M.3
Ashor, A.4
Keun-Hang, S.Y.5
Petroianu, G.6
-
159
-
-
0027432528
-
Identification and functional characterization of a new agonist site on nicotinic acetylcholine receptors of cultured hippocampal neurons
-
Pereira EF, Reinhardt-Maelicke S, Schrattenholz A, Maelicke A, Albuquerque EX. Identification and functional characterization of a new agonist site on nicotinic acetylcholine receptors of cultured hippocampal neurons. J Pharmacol Exp Ther 265: 1474-91 (1993).
-
(1993)
J Pharmacol Exp Ther
, vol.265
, pp. 1474-1491
-
-
Pereira, E.F.1
Reinhardt-Maelicke, S.2
Schrattenholz, A.3
Maelicke, A.4
Albuquerque, E.X.5
-
160
-
-
10744232323
-
Galantamine is an allosterically potentiating ligand of neuronal nicotinic but not of muscarinic acetylcholine receptors
-
Samochocki M, Hoffle A, Fehrenbacher A, Jostock R, Ludwig J, Christner C et al. Galantamine is an allosterically potentiating ligand of neuronal nicotinic but not of muscarinic acetylcholine receptors. J Pharmacol Exp Ther 305: 1024-36 (2003).
-
(2003)
J Pharmacol Exp Ther
, vol.305
, pp. 1024-1036
-
-
Samochocki, M.1
Hoffle, A.2
Fehrenbacher, A.3
Jostock, R.4
Ludwig, J.5
Christner, C.6
-
161
-
-
14344253935
-
Memantine blocks alpha7* nicotinic acetylcholine receptors more potently than n-methyl-D-aspartate receptors in rat hippocampal neurons
-
Aracava Y, Pereira EF, Maelicke A, Albuquerque EX. Memantine blocks alpha7* nicotinic acetylcholine receptors more potently than n-methyl-D-aspartate receptors in rat hippocampal neurons. J Pharmacol Exp Ther 312: 1195-205 (2005).
-
(2005)
J Pharmacol Exp Ther
, vol.312
, pp. 1195-1205
-
-
Aracava, Y.1
Pereira, E.F.2
Maelicke, A.3
Albuquerque, E.X.4
-
162
-
-
1642422286
-
Inhibition of human alpha 7 nicotinic acetylcholine receptors by open channel blockers of N-methyl-D-aspartate receptors
-
Maskell PD, Speder P, Newberry NR, Bermudez I. Inhibition of human alpha 7 nicotinic acetylcholine receptors by open channel blockers of N-methyl-D-aspartate receptors. Br J Pharmacol 140: 1313-9 (2003).
-
(2003)
Br J Pharmacol
, vol.140
, pp. 1313-1319
-
-
Maskell, P.D.1
Speder, P.2
Newberry, N.R.3
Bermudez, I.4
-
163
-
-
0034959817
-
Memantine inhibits efferent cholinergic transmission in the cochlea by blocking nicotinic acetylcholine receptors of outer hair cells
-
Oliver D, Ludwig J, Reisinger E, Zoellner W, Ruppersberg JP, Fakler B. Memantine inhibits efferent cholinergic transmission in the cochlea by blocking nicotinic acetylcholine receptors of outer hair cells. Mol Pharmacol 60: 183-9 (2001).
-
(2001)
Mol Pharmacol
, vol.60
, pp. 183-189
-
-
Oliver, D.1
Ludwig, J.2
Reisinger, E.3
Zoellner, W.4
Ruppersberg, J.P.5
Fakler, B.6
-
164
-
-
34249046017
-
Inhibition of the alpha9alpha10 nicotinic cholinergic receptor by neramexane, an open channel blocker of N-methyl-Daspartate receptors
-
Plazas PV, Savino J, Kracun S, Gomez-Casati ME, Katz E, Parsons CG, et al. Inhibition of the alpha9alpha10 nicotinic cholinergic receptor by neramexane, an open channel blocker of N-methyl-Daspartate receptors. Eur J Pharmacol 566: 11-9 (2007).
-
(2007)
Eur J Pharmacol
, vol.566
, pp. 11-19
-
-
Plazas, P.V.1
Savino, J.2
Kracun, S.3
Gomez-Casati, M.E.4
Katz, E.5
Parsons, C.G.6
-
165
-
-
0031977071
-
Open-channel blockers at the human alpha4beta2 neuronal nicotinic acetylcholine receptor
-
Buisson B, Bertrand D. Open-channel blockers at the human alpha4beta2 neuronal nicotinic acetylcholine receptor. Mol Pharmacol 53: 555-63 (1998).
-
(1998)
Mol Pharmacol
, vol.53
, pp. 555-563
-
-
Buisson, B.1
Bertrand, D.2
-
166
-
-
14044264719
-
Cholinergic drugs potentiate human nicotinic alpha4beta2 acetylcholine receptors by a competitive mechanism
-
Smulders CJ, Zwart R, Bermudez I, van Kleef RG, Groot-Kormelink PJ, Vijverberg HP. Cholinergic drugs potentiate human nicotinic alpha4beta2 acetylcholine receptors by a competitive mechanism. Eur J Pharmacol 509: 97-108 (2005).
-
(2005)
Eur J Pharmacol
, vol.509
, pp. 97-108
-
-
Smulders, C.J.1
Zwart, R.2
Bermudez, I.3
van Kleef, R.G.4
Groot-Kormelink, P.J.5
Vijverberg, H.P.6
-
167
-
-
27544456195
-
Cholinesterase inhibitors ameliorate behavioral deficits induced by MK-801 in mice
-
Csernansky JG, Martin M, Shah R, Bertchume A, Colvin J, Dong H. Cholinesterase inhibitors ameliorate behavioral deficits induced by MK-801 in mice. Neuropsychopharmacology 30: 2135-43 (2005).
-
(2005)
Neuropsychopharmacology
, vol.30
, pp. 2135-2143
-
-
Csernansky, J.G.1
Martin, M.2
Shah, R.3
Bertchume, A.4
Colvin, J.5
Dong, H.6
-
168
-
-
25644432066
-
Modulation of N-methyl-D-aspartate receptors by donepezil in rat cortical neurons
-
Moriguchi S, Zhao X, Marszalec W, Yeh JZ, Narahashi T. Modulation of N-methyl-D-aspartate receptors by donepezil in rat cortical neurons. J Pharmacol Exp Ther 315: 125-35 (2005).
-
(2005)
J Pharmacol Exp Ther
, vol.315
, pp. 125-135
-
-
Moriguchi, S.1
Zhao, X.2
Marszalec, W.3
Yeh, J.Z.4
Narahashi, T.5
-
169
-
-
84872618461
-
γ-Aminobutyric acid type a receptor inhibition triggers a nicotinic neuroprotective mechanism
-
Ferchmin PA, Pérez D, Castro Alvarez W, Penzo MA, Maldonado HM, Eterovic VA. γ-Aminobutyric acid type a receptor inhibition triggers a nicotinic neuroprotective mechanism. J Neurosci Res 91: 416-425 (2013).
-
(2013)
J Neurosci Res
, vol.91
, pp. 416-425
-
-
Ferchmin, P.A.1
Pérez, D.2
Castro Alvarez, W.3
Penzo, M.A.4
Maldonado, H.M.5
Eterovic, V.A.6
-
170
-
-
84874617868
-
Improvement of attentional function with antagonism of nicotinic receptors in female rats
-
Levin ED, Cauley M, Rezvani AH. Improvement of attentional function with antagonism of nicotinic receptors in female rats. Eur J Pharmacol 702: 269-274 (2013).
-
(2013)
Eur J Pharmacol
, vol.702
, pp. 269-274
-
-
Levin, E.D.1
Cauley, M.2
Rezvani, A.H.3
|