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Volumn 88, Issue 5, 2004, Pages 1186-1193

α7-Nicotinic acetylcholine receptors mediate an Aβ 1-42-induced increase in the level of acetylcholinesterase in primary cortical neurones

Author keywords

Acetylcholinesterase; Alzheimer's disease; Amyloid; Cholinergic; Nicotinic

Indexed keywords

ACETYLCHOLINESTERASE; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; BUNGAROTOXIN RECEPTOR; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL L TYPE; CALCIUM CHANNEL N TYPE; CHOLINE; NICOTINE; NICOTINIC AGENT; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG; ALPHA-BUNGAROTOXIN RECEPTOR; AMYLOID BETA PROTEIN (1 28); AMYLOID BETA PROTEIN (1 42); AMYLOID BETA-PROTEIN (1-28); AMYLOID BETA-PROTEIN (1-42); CALCIUM CHANNEL; PEPTIDE FRAGMENT;

EID: 1442348421     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2003.02296.x     Document Type: Article
Times cited : (76)

References (63)
  • 1
    • 0031410384 scopus 로고    scopus 로고
    • Choline is a selective agonist of α7 nicotinic acetylcholine receptors in the rat brain neurons
    • Alkondon M., Pereira E. F., Cortes W. S., Maelicke A. and Albuquerque E. X. (1997) Choline is a selective agonist of α7 nicotinic acetylcholine receptors in the rat brain neurons. Eur. J. Neurosci. 9, 2734-2742.
    • (1997) Eur. J. Neurosci. , vol.9 , pp. 2734-2742
    • Alkondon, M.1    Pereira, E.F.2    Cortes, W.S.3    Maelicke, A.4    Albuquerque, E.X.5
  • 2
    • 0037145719 scopus 로고    scopus 로고
    • Impairment of cholinergic neurotransmission in adult and aged transgenic Tg2576 mouse brain expressing the Swedish mutation of human β-amyloid precursor protein
    • Apelt J., Kumar A. and Schliebs R. (2002) Impairment of cholinergic neurotransmission in adult and aged transgenic Tg2576 mouse brain expressing the Swedish mutation of human β-amyloid precursor protein. Brain Res. 953, 17-30.
    • (2002) Brain Res. , vol.953 , pp. 17-30
    • Apelt, J.1    Kumar, A.2    Schliebs, R.3
  • 3
    • 0020545113 scopus 로고
    • Molecular forms of acetylcholinesterase in senile dementia of Alzheimer type: Selective loss of the intermediate (10S) form
    • Atack J. R., Perry E. K., Bonham J. R., Perry R. H., Tomlinson B. E., Blessed G. and Fairbaim A. (1983) Molecular forms of acetylcholinesterase in senile dementia of Alzheimer type: selective loss of the intermediate (10S) form. Neurosci. Lett. 40, 199-204.
    • (1983) Neurosci. Lett. , vol.40 , pp. 199-204
    • Atack, J.R.1    Perry, E.K.2    Bonham, J.R.3    Perry, R.H.4    Tomlinson, B.E.5    Blessed, G.6    Fairbaim, A.7
  • 4
    • 0036318339 scopus 로고    scopus 로고
    • Selective nicotinic receptor consequences in APP (SWE) transgenic mice
    • Bednar I., Paterson D., Marutle A. et al. (2002) Selective nicotinic receptor consequences in APP (SWE) transgenic mice. Mol. Cell Neurosci. 20, 354-365.
    • (2002) Mol. Cell Neurosci. , vol.20 , pp. 354-365
    • Bednar, I.1    Paterson, D.2    Marutle, A.3
  • 5
    • 0023737807 scopus 로고
    • The distribution of neuritic plaques and acetylcholinesterase staining in the amygdala in Alzheimer's disease
    • Brashear H. R., Godec M. S. and Carlsen J. (1988) The distribution of neuritic plaques and acetylcholinesterase staining in the amygdala in Alzheimer's disease. Neurology 38, 1694-1699.
    • (1988) Neurology , vol.38 , pp. 1694-1699
    • Brashear, H.R.1    Godec, M.S.2    Carlsen, J.3
  • 6
    • 0020987006 scopus 로고
    • Molecular forms of acetylcholinesterase in brain, nerve and muscle: Nature, localization and dynamics
    • Brimijoin S. (1983) Molecular forms of acetylcholinesterase in brain, nerve and muscle: nature, localization and dynamics. Prog. Neurobiol. 21, 291-322.
    • (1983) Prog. Neurobiol. , vol.21 , pp. 291-322
    • Brimijoin, S.1
  • 7
    • 0032589578 scopus 로고    scopus 로고
    • The α7 nicotinic acetylcholine receptor in neuronal plasticity
    • Broide R. S. and Leslie F. M. (1999) The α7 nicotinic acetylcholine receptor in neuronal plasticity. Mol. Neurobiol. 20, 1-16.
    • (1999) Mol. Neurobiol. , vol.20 , pp. 1-16
    • Broide, R.S.1    Leslie, F.M.2
  • 8
    • 0030941561 scopus 로고    scopus 로고
    • Pharmacological characterization of recombinant human neuronal nicotinic acetylcholine receptors hα2β2, hα2β4, hα3β2, hα3β4, hα4β2, hα4β4 and hα4 expressed in Xenopus oocytes
    • Chavez-Noriega L. E., Crona J. H., Washburn M. S., Urrutia A., Elliott K. J. and Johnson E. C. (1997) Pharmacological characterization of recombinant human neuronal nicotinic acetylcholine receptors hα2β2, hα2β4, hα3β2, hα3β4, hα4β2, hα4β4 and hα4 expressed in Xenopus oocytes. J. Pharmacol. Exp. Ther. 280, 346-356.
    • (1997) J. Pharmacol. Exp. Ther. , vol.280 , pp. 346-356
    • Chavez-Noriega, L.E.1    Crona, J.H.2    Washburn, M.S.3    Urrutia, A.4    Elliott, K.J.5    Johnson, E.C.6
  • 9
    • 0027461090 scopus 로고
    • An amyloid peptide, βA4, 25-35, mimics the function of substance P on modulation of nicotine-evoked secretion and desensitization in cultured bovine adrenal chromaffin cells
    • Cheung N. S., Small D. H. and Livett B. G. (1993) An amyloid peptide, βA4, 25-35, mimics the function of substance P on modulation of nicotine-evoked secretion and desensitization in cultured bovine adrenal chromaffin cells. J. Neurochem. 60, 1163-1166.
    • (1993) J. Neurochem. , vol.60 , pp. 1163-1166
    • Cheung, N.S.1    Small, D.H.2    Livett, B.G.3
  • 10
    • 0035875962 scopus 로고    scopus 로고
    • β-amyloid activates the mitogen-activated protein kinase cascade via hippocampal α7 nicotinic acetylcholine receptors: In vitro and in vivo mechanisms related to Alzheimer's disease
    • Dineley K. T., Westerman M., Bui D., Bell K., Hsiao Ashe K. and Sweatt J. D. (2001) β-amyloid activates the mitogen-activated protein kinase cascade via hippocampal α7 nicotinic acetylcholine receptors: in vitro and in vivo mechanisms related to Alzheimer's disease. J. Neurosci. 21, 4125-4133.
    • (2001) J. Neurosci. , vol.21 , pp. 4125-4133
    • Dineley, K.T.1    Westerman, M.2    Bui, D.3    Bell, K.4    Hsiao Ashe, K.5    Sweatt, J.D.6
  • 11
    • 0037067717 scopus 로고    scopus 로고
    • β-Amyloid peptide activates α7 nicotinic acetylcholine receptors expressed in Xenopus oocytes
    • Dineley K. T., Bell K. A., Bui D. and Sweatt J. D. (2002) β-Amyloid peptide activates α7 nicotinic acetylcholine receptors expressed in Xenopus oocytes. J. Biol. Chem. 277, 25056-25061.
    • (2002) J. Biol. Chem. , vol.277 , pp. 25056-25061
    • Dineley, K.T.1    Bell, K.A.2    Bui, D.3    Sweatt, J.D.4
  • 12
    • 0028247930 scopus 로고
    • Alzheimer's disease amyloid precursor protein (Aβ PP): Proteolytic processing, secretases and βA4 amyloid production
    • Evin G. and Beyreuther K. and Masters C. L. (1994) Alzheimer's disease amyloid precursor protein (Aβ PP): proteolytic processing, secretases and βA4 amyloid production. Amyloid 1, 263-280.
    • (1994) Amyloid , vol.1 , pp. 263-280
    • Evin, G.1    Beyreuther, K.2    Masters, C.L.3
  • 13
    • 0022616905 scopus 로고
    • Distribution of the molecular forms of acetylcholinesterase in human brain: Alterations in dementia of the Alzheimer type
    • Fishman E. B., Siek G. C., MacCallum R. D., Bird E. D., Volicer L. and Marquis J. K. (1986) Distribution of the molecular forms of acetylcholinesterase in human brain: alterations in dementia of the Alzheimer type. Ann. Neurol. 19, 246-252.
    • (1986) Ann. Neurol. , vol.19 , pp. 246-252
    • Fishman, E.B.1    Siek, G.C.2    MacCallum, R.D.3    Bird, E.D.4    Volicer, L.5    Marquis, J.K.6
  • 15
    • 3342978711 scopus 로고
    • Enzyme histochemical studies of senile plaques
    • Friede R. L. (1965) Enzyme histochemical studies of senile plaques. J. Neuropathol. Exp. Neurol. 24, 477-491.
    • (1965) J. Neuropathol. Exp. Neurol. , vol.24 , pp. 477-491
    • Friede, R.L.1
  • 16
    • 0028980783 scopus 로고
    • Intracellular production of βA4 amyloid of Alzheimer's disease: Modulation by phosphoramidon and lack of coupling to the secretion of the amyloid precursor protein
    • Fuller S. J., Storey E., Li Q. X., Smith A. I., Beyreuther K. and Masters C. L. (1995) Intracellular production of βA4 amyloid of Alzheimer's disease: modulation by phosphoramidon and lack of coupling to the secretion of the amyloid precursor protein. Biochemistry 34, 8091-8098.
    • (1995) Biochemistry , vol.34 , pp. 8091-8098
    • Fuller, S.J.1    Storey, E.2    Li, Q.X.3    Smith, A.I.4    Beyreuther, K.5    Masters, C.L.6
  • 17
    • 0028838303 scopus 로고
    • Comparative pharmacology of epibatidine: A potent agonist for neuronal nicotinic acetylcholine receptors
    • Gerzanich V., Peng X., Wang F., Wells G., Anand R., Fletcher S. and Lindstrom J. (1995) Comparative pharmacology of epibatidine: a potent agonist for neuronal nicotinic acetylcholine receptors. Mol. Pharmacol. 48, 774-782.
    • (1995) Mol. Pharmacol. , vol.48 , pp. 774-782
    • Gerzanich, V.1    Peng, X.2    Wang, F.3    Wells, G.4    Anand, R.5    Fletcher, S.6    Lindstrom, J.7
  • 18
    • 0024417125 scopus 로고
    • Special properties of cholinesterases in the cerebral cortex of Alzheimer's disease
    • Geula C. and Mesulam M. (1989) Special properties of cholinesterases in the cerebral cortex of Alzheimer's disease. Brain Res. 498, 185-189.
    • (1989) Brain Res. , vol.498 , pp. 185-189
    • Geula, C.1    Mesulam, M.2
  • 19
    • 0026499929 scopus 로고
    • Ultrastructural localization of acetylcholinesterase in neurofibrillary tangles, neuropil threads and senile plaques in aged and Alzheimer's brain
    • Gomez-Ramos P., Mufson E. J. and Moran M. A. (1992) Ultrastructural localization of acetylcholinesterase in neurofibrillary tangles, neuropil threads and senile plaques in aged and Alzheimer's brain. Brain Res. 569, 229-237.
    • (1992) Brain Res. , vol.569 , pp. 229-237
    • Gomez-Ramos, P.1    Mufson, E.J.2    Moran, M.A.3
  • 20
    • 0037440717 scopus 로고    scopus 로고
    • Amyloid β(1-42) peptide alters the gating of human and mouse alpha-bungarotoxin-sensitive nicotinic receptors
    • Grassi F., Palma E., Tonini R., Amici M., Ballivet M. and Eusebi F. (2003) Amyloid β(1-42) peptide alters the gating of human and mouse alpha-bungarotoxin-sensitive nicotinic receptors. J. Physiol. 547, 147-157.
    • (2003) J. Physiol. , vol.547 , pp. 147-157
    • Grassi, F.1    Palma, E.2    Tonini, R.3    Amici, M.4    Ballivet, M.5    Eusebi, F.6
  • 21
    • 0033568704 scopus 로고    scopus 로고
    • Structural roles of acetylcholinesterase variants in biology and pathology
    • Grisaru D., Stemfeld M., Eldor A., Glick D. and Soreq H. (1999) Structural roles of acetylcholinesterase variants in biology and pathology. Eur. J. Biochem. 264, 672-686.
    • (1999) Eur. J. Biochem. , vol.264 , pp. 672-686
    • Grisaru, D.1    Stemfeld, M.2    Eldor, A.3    Glick, D.4    Soreq, H.5
  • 22
    • 0032812637 scopus 로고    scopus 로고
    • Differential blockade of rat α3β4 and α7 neuronal nicotinic receptors by ω-conotoxin MVIIC, ω-conotoxin GVIA and diltiazem
    • Herrero C. J., García-Palomero E., Pintado A. J., García A. G. and Montiel C. (1999) Differential blockade of rat α3β4 and α7 neuronal nicotinic receptors by ω-conotoxin MVIIC, ω-conotoxin GVIA and diltiazem. Br. J. Pharmacol. 127, 1375-1387.
    • (1999) Br. J. Pharmacol. , vol.127 , pp. 1375-1387
    • Herrero, C.J.1    García-Palomero, E.2    Pintado, A.J.3    García, A.G.4    Montiel, C.5
  • 23
    • 0029661424 scopus 로고    scopus 로고
    • Analysis of heterogeneous βA4 peptides in human cerebrospinal fluid and blood by a newly developed sensitive western blot assay
    • Ida N., Hartmann T., Pantel J., Schröder J., Zerfass R., Förstl H., Sandbrink R., Masters C. L. and Beyreuther K. (1996) Analysis of heterogeneous βA4 peptides in human cerebrospinal fluid and blood by a newly developed sensitive western blot assay. J. Biol. Chem. 271, 22908-22914.
    • (1996) J. Biol. Chem. , vol.271 , pp. 22908-22914
    • Ida, N.1    Hartmann, T.2    Pantel, J.3    Schröder, J.4    Zerfass, R.5    Förstl, H.6    Sandbrink, R.7    Masters, C.L.8    Beyreuther, K.9
  • 25
    • 0035836747 scopus 로고    scopus 로고
    • β-Amyloid peptide blocks the response of α7-containing nicotinic receptors on hippocampal neurons
    • Liu Q., Kawai H. and Berg D. K. (2001) β-Amyloid peptide blocks the response of α7-containing nicotinic receptors on hippocampal neurons. Proc. Natl Acad. Sci. USA 98, 4734-4739.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 4734-4739
    • Liu, Q.1    Kawai, H.2    Berg, D.K.3
  • 26
    • 13144305064 scopus 로고    scopus 로고
    • Unmasking the functions of the chromaffin cell α7 nicotinic receptor by using short pulses of acetylcholine and selective blockers
    • Lopez M. G., Montiel C., Herrero C. J. et al. (1998) Unmasking the functions of the chromaffin cell α7 nicotinic receptor by using short pulses of acetylcholine and selective blockers. Proc. Natl Acad. Sci. USA 95, 14184-14189.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 14184-14189
    • Lopez, M.G.1    Montiel, C.2    Herrero, C.J.3
  • 27
    • 0028063039 scopus 로고
    • Regulation of acetylcholinesterase mRNA stability by calcium during differentiation from myoblasts to myotubes
    • Luo Z. D., Fuentes M. E. and Taylor P. (1994) Regulation of acetylcholinesterase mRNA stability by calcium during differentiation from myoblasts to myotubes. J. Biol. Chem. 269, 27216-27223.
    • (1994) J. Biol. Chem. , vol.269 , pp. 27216-27223
    • Luo, Z.D.1    Fuentes, M.E.2    Taylor, P.3
  • 28
    • 0029931262 scopus 로고    scopus 로고
    • Acetylcholinesterase and nicotinic acetylcholine receptor expression diverge in muscular dysgenic mice lacking the L-type calcium channel
    • Luo Z. D., Pincon-Raymond M. and Taylor P. (1996) Acetylcholinesterase and nicotinic acetylcholine receptor expression diverge in muscular dysgenic mice lacking the L-type calcium channel. J. Neurochem. 67, 111-118.
    • (1996) J. Neurochem. , vol.67 , pp. 111-118
    • Luo, Z.D.1    Pincon-Raymond, M.2    Taylor, P.3
  • 29
    • 0032707028 scopus 로고    scopus 로고
    • Calcineurin enhances acetylcholinesterase mRNA stability during C2-C3 muscle cell differentiation
    • Luo Z. D., Wang Y., Werlen G., Camp S., Chien K. R. and Taylor P. (1999) Calcineurin enhances acetylcholinesterase mRNA stability during C2-C3 muscle cell differentiation. Mol. Pharmacol. 56, 886-894.
    • (1999) Mol. Pharmacol. , vol.56 , pp. 886-894
    • Luo, Z.D.1    Wang, Y.2    Werlen, G.3    Camp, S.4    Chien, K.R.5    Taylor, P.6
  • 32
    • 0037219182 scopus 로고    scopus 로고
    • Involvement of oxidative stress in the enhancement of acetylcholinesterase activity induced by amyloid β-peptide
    • Melo J. B., Agostinho P. and Oliveira C. R. (2003) Involvement of oxidative stress in the enhancement of acetylcholinesterase activity induced by amyloid β-peptide. Neurosci. Res. 45, 117-127.
    • (2003) Neurosci. Res. , vol.45 , pp. 117-127
    • Melo, J.B.1    Agostinho, P.2    Oliveira, C.R.3
  • 33
    • 0022616589 scopus 로고
    • Alzheimer plaques and cortical cholinergic innervation
    • Mesulam M. M. (1986) Alzheimer plaques and cortical cholinergic innervation. Neuroscience 17, 275-276.
    • (1986) Neuroscience , vol.17 , pp. 275-276
    • Mesulam, M.M.1
  • 34
    • 0024238709 scopus 로고
    • Acetylcholinesterase-rich pyramidal neurons in the human neocortex and hippocampus: Absence at birth, development during the life span, and dissolution in Alzheimer's disease
    • Mesulam M. M. and Geula C. (1988) Acetylcholinesterase-rich pyramidal neurons in the human neocortex and hippocampus: absence at birth, development during the life span, and dissolution in Alzheimer's disease. Ann. Neurol. 24, 765-773.
    • (1988) Ann. Neurol. , vol.24 , pp. 765-773
    • Mesulam, M.M.1    Geula, C.2
  • 35
    • 0036310672 scopus 로고    scopus 로고
    • Toxicity of substrate-bound amyloid peptides on vascular smooth muscle cells is enhanced by homocysteine
    • Mok S. S., Turner B. J., Beyreuther K., Masters C. L., Barrow C. J. and Small D. H. (2002) Toxicity of substrate-bound amyloid peptides on vascular smooth muscle cells is enhanced by homocysteine. Eur. J. Biochem. 269, 3014-3022.
    • (2002) Eur. J. Biochem. , vol.269 , pp. 3014-3022
    • Mok, S.S.1    Turner, B.J.2    Beyreuther, K.3    Masters, C.L.4    Barrow, C.J.5    Small, D.H.6
  • 36
    • 0030576581 scopus 로고    scopus 로고
    • An evaluation of neuronal nicotinic acetylcholine receptor activation by quaternary nitrogen compounds indicates that choline is selective for the α7 subtype
    • Papke R. L., Bencherif M. and Lippiello P. (1996) An evaluation of neuronal nicotinic acetylcholine receptor activation by quaternary nitrogen compounds indicates that choline is selective for the α7 subtype. Neurosci. Lett. 213, 201-204.
    • (1996) Neurosci. Lett. , vol.213 , pp. 201-204
    • Papke, R.L.1    Bencherif, M.2    Lippiello, P.3
  • 37
    • 0018924532 scopus 로고
    • The cholinergic system in old age and Alzheimer's disease
    • Perry E. K. (1980) The cholinergic system in old age and Alzheimer's disease. Age Ageing 9, 1-8.
    • (1980) Age Ageing , vol.9 , pp. 1-8
    • Perry, E.K.1
  • 38
    • 0028890920 scopus 로고
    • Alteration in nicotine binding sites in Parkinson's disease. Lewy body dementia and Alzheimer's disease: Possible index of early neuropathology
    • Perry E. K., Morris C. M., Court J. A., Cheng A., Fairbaim A. F., McKeith I. G., Irving D., Brown A. and Perry R. H. (1995) Alteration in nicotine binding sites in Parkinson's disease, Lewy body dementia and Alzheimer's disease: possible index of early neuropathology. Neuroscience 64, 385-395.
    • (1995) Neuroscience , vol.64 , pp. 385-395
    • Perry, E.K.1    Morris, C.M.2    Court, J.A.3    Cheng, A.4    Fairbaim, A.F.5    McKeith, I.G.6    Irving, D.7    Brown, A.8    Perry, R.H.9
  • 39
    • 19244378105 scopus 로고    scopus 로고
    • Nicotinic receptor subtypes in human brain ageing. Alzheimer and Lewy body diseases
    • Perry E. K., Martin-Ruiz C., Lee M. et al. (2000) Nicotinic receptor subtypes in human brain ageing, Alzheimer and Lewy body diseases. Eur. J. Pharmacol. 393, 215-222.
    • (2000) Eur. J. Pharmacol. , vol.393 , pp. 215-222
    • Perry, E.K.1    Martin-Ruiz, C.2    Lee, M.3
  • 40
    • 0035219699 scopus 로고    scopus 로고
    • β-Amyloid (1-42) peptide directly modulates nicotinic receptors in the rat hippocampal slice
    • Pettit D. L., Shao Z. and Yakel J. L. (2001) β-Amyloid (1-42) peptide directly modulates nicotinic receptors in the rat hippocampal slice. J. Neurosci. 21, RC120.
    • (2001) J. Neurosci. , vol.21
    • Pettit, D.L.1    Shao, Z.2    Yakel, J.L.3
  • 41
    • 0033982030 scopus 로고    scopus 로고
    • Substrate-bound β-amyloid peptides inhibit cell adhesion and neurite outgrowth in primary neuronal cultures
    • Postuma R. B., He W., Nunan J., Beyreuther K., Masters C. L., Barrow C. J. and Small D. H. (2000) Substrate-bound β-amyloid peptides inhibit cell adhesion and neurite outgrowth in primary neuronal cultures. J. Neurochem. 74, 1122-1130.
    • (2000) J. Neurochem. , vol.74 , pp. 1122-1130
    • Postuma, R.B.1    He, W.2    Nunan, J.3    Beyreuther, K.4    Masters, C.L.5    Barrow, C.J.6    Small, D.H.7
  • 42
    • 0035910329 scopus 로고    scopus 로고
    • Altered glycosylation of cerebrospinal fluid butyrylcholinesterase in Alzheimer's disease
    • Sáez-Valero J. and Small D. H. (2001) Altered glycosylation of cerebrospinal fluid butyrylcholinesterase in Alzheimer's disease. Brain Res. 889, 247-250.
    • (2001) Brain Res. , vol.889 , pp. 247-250
    • Sáez-Valero, J.1    Small, D.H.2
  • 43
    • 34547392200 scopus 로고    scopus 로고
    • Glycosylation of acetylcholinesterase as diagnostic marker for Alzheimer's disease
    • Sáez-Valero J., Sbema G., McLean C. A., Masters C. L. and Small D. H. (1997) Glycosylation of acetylcholinesterase as diagnostic marker for Alzheimer's disease. Lancet 350, 929.
    • (1997) Lancet , vol.350 , pp. 929
    • Sáez-Valero, J.1    Sbema, G.2    McLean, C.A.3    Masters, C.L.4    Small, D.H.5
  • 44
    • 0345390947 scopus 로고    scopus 로고
    • Molecular isoform distribution and glycosylation of acetylcholinesterase are altered in brain and cerebrospinal fluid of patients with Alzheimer's disease
    • Sáez-Valero J., Sbema G., McLean C. A. and Small D. H. (1999) Molecular isoform distribution and glycosylation of acetylcholinesterase are altered in brain and cerebrospinal fluid of patients with Alzheimer's disease. J. Neurochem. 72, 1600-1608.
    • (1999) J. Neurochem. , vol.72 , pp. 1600-1608
    • Sáez-Valero, J.1    Sbema, G.2    McLean, C.A.3    Small, D.H.4
  • 45
    • 0033784130 scopus 로고    scopus 로고
    • Altered glycosylation of acetylcholinesterase in lumbar cerebrospinal fluid of patients with Alzheimer's disease
    • Sáez-Valero J., Barquero M. S., Marcos A., McLean C. A. and Small D. H. (2000) Altered glycosylation of acetylcholinesterase in lumbar cerebrospinal fluid of patients with Alzheimer's disease. J. Neurol. Neurosurg. Psychiatry 69, 664-667.
    • (2000) J. Neurol. Neurosurg. Psychiatry , vol.69 , pp. 664-667
    • Sáez-Valero, J.1    Barquero, M.S.2    Marcos, A.3    McLean, C.A.4    Small, D.H.5
  • 46
    • 0037424301 scopus 로고    scopus 로고
    • Acetylcholinesterase is increased in mouse neuronal and astrocyte cultures are treatment with β-amyloid peptides
    • Sáez-Valero J., Fodero L. R., White A. R., Barrow C. J. and Small D. H. (2003) Acetylcholinesterase is increased in mouse neuronal and astrocyte cultures are treatment with β-amyloid peptides. Brain Res. 965, 283-286.
    • (2003) Brain Res. , vol.965 , pp. 283-286
    • Sáez-Valero, J.1    Fodero, L.R.2    White, A.R.3    Barrow, C.J.4    Small, D.H.5
  • 47
    • 1842375103 scopus 로고    scopus 로고
    • The amyloid β-protein of Alzheimer's disease increases acetylcholinesterase expression by increasing intracellular calcium in embryonal carcinoma P19 cells
    • Sbema G., Saez-Valero J., Beyreuther K., Masters C. L. and Small D. H. (1997) The amyloid β-protein of Alzheimer's disease increases acetylcholinesterase expression by increasing intracellular calcium in embryonal carcinoma P19 cells. J. Neurochem. 69, 1177-1184.
    • (1997) J. Neurochem. , vol.69 , pp. 1177-1184
    • Sbema, G.1    Saez-Valero, J.2    Beyreuther, K.3    Masters, C.L.4    Small, D.H.5
  • 48
    • 0031754362 scopus 로고    scopus 로고
    • Acetylcholinesterase is increased in the brains of transgenic mice expressing the C-terminal fragment (CT100) of the β-amyloid protein precursor of Alzheimer's disease
    • Sbema G., Saez-Valero J., Li Q. X., Czech C., Beyreuther K. and Masters C. L., McLean C. A. and Small D. H. (1998) Acetylcholinesterase is increased in the brains of transgenic mice expressing the C-terminal fragment (CT100) of the β-amyloid protein precursor of Alzheimer's disease. J. Neurochem. 71, 723-731.
    • (1998) J. Neurochem. , vol.71 , pp. 723-731
    • Sbema, G.1    Saez-Valero, J.2    Li, Q.X.3    Czech, C.4    Beyreuther, K.5    Masters, C.L.6    McLean, C.A.7    Small, D.H.8
  • 49
    • 0028267440 scopus 로고
    • Normal and abnormal biology of the β-amyloid precursor protein
    • Selkoe D. J. (1994) Normal and abnormal biology of the β-amyloid precursor protein. Annu. Rev. Neurosci. 17, 489-517.
    • (1994) Annu. Rev. Neurosci. , vol.17 , pp. 489-517
    • Selkoe, D.J.1
  • 50
    • 0029897490 scopus 로고    scopus 로고
    • Non-classical actions of cholinesterases: Role in cellular differentiation, tumorigenesis and Alzheimer's disease
    • Small D. H., Michaelson S. and Sbema G. (1996) Non-classical actions of cholinesterases: role in cellular differentiation, tumorigenesis and Alzheimer's disease. Neurochem. Int. 28, 453-483.
    • (1996) Neurochem. Int. , vol.28 , pp. 453-483
    • Small, D.H.1    Michaelson, S.2    Sbema, G.3
  • 51
    • 0035433962 scopus 로고    scopus 로고
    • Alzheimer's disease and Aβ toxicity: From top to bottom
    • Small D. H., Mok S. S. and Bornstein J. C. (2001) Alzheimer's disease and Aβ toxicity: from top to bottom. Nat. Rev. Neurosci. 2, 595-598.
    • (2001) Nat. Rev. Neurosci. , vol.2 , pp. 595-598
    • Small, D.H.1    Mok, S.S.2    Bornstein, J.C.3
  • 52
    • 0022186670 scopus 로고
    • Measurement of protein using bicinchoninic acid
    • Smith P. K., Krohn R. I., Hermanson G. T. et al. (1985) Measurement of protein using bicinchoninic acid. Anal. Biochem. 150, 76-85.
    • (1985) Anal. Biochem. , vol.150 , pp. 76-85
    • Smith, P.K.1    Krohn, R.I.2    Hermanson, G.T.3
  • 53
    • 0028031486 scopus 로고
    • Structural determinants of the Alzheimer's amyloid β-peptide
    • Soto C., Branes M. C., Alvarez J. and Inestrosa N. C. (1994) Structural determinants of the Alzheimer's amyloid β-peptide. J. Neurochem. 63, 1191-1198.
    • (1994) J. Neurochem. , vol.63 , pp. 1191-1198
    • Soto, C.1    Branes, M.C.2    Alvarez, J.3    Inestrosa, N.C.4
  • 54
    • 0028174977 scopus 로고
    • The cholinesterases: From genes to proteins
    • Taylor P. and Radic Z. (1994) The cholinesterases: from genes to proteins. Annu. Rev. Pharmacol. Toxicol. 34, 281-320.
    • (1994) Annu. Rev. Pharmacol. Toxicol. , vol.34 , pp. 281-320
    • Taylor, P.1    Radic, Z.2
  • 57
    • 0033624509 scopus 로고    scopus 로고
    • Amyloid peptide Aβ(1-42) binds selectively and with picomolar affinity to α7 nicotinic acetylcholine receptors
    • Wang H.-Y., Lee D. H. S., Davis C. B. and Shank R. P. (2000a) Amyloid peptide Aβ(1-42) binds selectively and with picomolar affinity to α7 nicotinic acetylcholine receptors. J. Neurochem. 75, 1155-1161.
    • (2000) J. Neurochem. , vol.75 , pp. 1155-1161
    • Wang, H.-Y.1    Lee, D.H.S.2    Davis, C.B.3    Shank, R.P.4
  • 58
    • 0042357192 scopus 로고    scopus 로고
    • α7 nicotinic acetylcholine receptors mediate β-amyloid peptides-induced tau protein phosphorylation
    • Wang H.-Y., Li W., Benedetti N. J. and Lee D. H. S. (2003) α7 nicotinic acetylcholine receptors mediate β-amyloid peptides-induced tau protein phosphorylation. J. Biol. Chem. 278, 31547-31553.
    • (2003) J. Biol. Chem. , vol.278 , pp. 31547-31553
    • Wang, H.-Y.1    Li, W.2    Benedetti, N.J.3    Lee, D.H.S.4
  • 60
    • 0025160022 scopus 로고
    • Methyllycaconitine: A selective probe for neuronal α-bungarotoxin binding sites
    • Ward J. M., Cockcroft V. B., Lunt G. G., Smillie F. S. and Wonnacott S. (1990) Methyllycaconitine: a selective probe for neuronal α-bungarotoxin binding sites. FEBS Lett. 270, 45-48.
    • (1990) FEBS Lett. , vol.270 , pp. 45-48
    • Ward, J.M.1    Cockcroft, V.B.2    Lunt, G.G.3    Smillie, F.S.4    Wonnacott, S.5
  • 61
    • 0032971370 scopus 로고    scopus 로고
    • Expression of nicotinic acetylcholine receptor subunits in the cerebral cortex in Alzheimer's disease: Histotopographical correlation with amyloid plaques and hyperphosphorylated-tau protein
    • Wevers A., Monteggia L., Nowacki S. et al. (1999) Expression of nicotinic acetylcholine receptor subunits in the cerebral cortex in Alzheimer's disease: histotopographical correlation with amyloid plaques and hyperphosphorylated-tau protein. Eur. J. Neurosci. 11, 2551-2565.
    • (1999) Eur. J. Neurosci. , vol.11 , pp. 2551-2565
    • Wevers, A.1    Monteggia, L.2    Nowacki, S.3
  • 63
    • 0031595642 scopus 로고    scopus 로고
    • Rat α3/β4 subtype of neuronal nicotinic acetylcholine receptor stably expressed in a transfected cell line: Pharmacology of ligand binding and function
    • Xiao Y., Meyer E. L., Thompson J. M., Surin A., Wroblewski J. and Kellar K. J. (1998) Rat α3/β4 subtype of neuronal nicotinic acetylcholine receptor stably expressed in a transfected cell line: pharmacology of ligand binding and function. Mol. Pharmacol. 54, 322-333.
    • (1998) Mol. Pharmacol. , vol.54 , pp. 322-333
    • Xiao, Y.1    Meyer, E.L.2    Thompson, J.M.3    Surin, A.4    Wroblewski, J.5    Kellar, K.J.6


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