메뉴 건너뛰기




Volumn 83, Issue , 2013, Pages 71-97

Genetics of Immune Recognition and Response in Drosophila host defense

Author keywords

[No Author keywords available]

Indexed keywords


EID: 84880710187     PISSN: 00652660     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-12-407675-4.00002-X     Document Type: Chapter
Times cited : (17)

References (115)
  • 2
    • 84855274258 scopus 로고    scopus 로고
    • Wall teichoic acids of Staphylococcus aureus limit recognition by the drosophila peptidoglycan recognition protein-SA to promote pathogenicity
    • Atilano M.L., Yates J., Glittenberg M., Filipe S.R., Ligoxygakis P. Wall teichoic acids of Staphylococcus aureus limit recognition by the drosophila peptidoglycan recognition protein-SA to promote pathogenicity. PLoS Pathogens 2011, 7(12):e1002421. 10.1371/journal.ppat.1002421.
    • (2011) PLoS Pathogens , vol.7 , Issue.12
    • Atilano, M.L.1    Yates, J.2    Glittenberg, M.3    Filipe, S.R.4    Ligoxygakis, P.5
  • 4
    • 77953316126 scopus 로고    scopus 로고
    • An in vivo RNA interference screen identifies gene networks controlling Drosophila melanogaster blood cell homeostasis
    • Avet-Rochex A., Boyer K., Polesello C., Gobert V., Osman D., Roch F., et al. An in vivo RNA interference screen identifies gene networks controlling Drosophila melanogaster blood cell homeostasis. BMC Developmental Biology 2010, 10(1):65. 10.1186/1471-213X-10-65.
    • (2010) BMC Developmental Biology , vol.10 , Issue.1 , pp. 65
    • Avet-Rochex, A.1    Boyer, K.2    Polesello, C.3    Gobert, V.4    Osman, D.5    Roch, F.6
  • 5
    • 0037295801 scopus 로고    scopus 로고
    • A single gene that promotes interaction of a phytopathogenic bacterium with its insect vector, Drosophila melanogaster
    • Basset A., Tzou P., Lemaitre B., Boccard F. A single gene that promotes interaction of a phytopathogenic bacterium with its insect vector, Drosophila melanogaster. EMBO Reports 2003, 4(2):205-209. 10.1038/sj.embor.embor730.
    • (2003) EMBO Reports , vol.4 , Issue.2 , pp. 205-209
    • Basset, A.1    Tzou, P.2    Lemaitre, B.3    Boccard, F.4
  • 6
    • 75149154705 scopus 로고    scopus 로고
    • FOXO-dependent regulation of innate immune homeostasis
    • Becker T., Loch G., Beyer M., Zinke I., Aschenbrenner A.C., Carrera P., et al. FOXO-dependent regulation of innate immune homeostasis. Nature 2010, 463(7279):369-373. 10.1038/nature08698.
    • (2010) Nature , vol.463 , Issue.7279 , pp. 369-373
    • Becker, T.1    Loch, G.2    Beyer, M.3    Zinke, I.4    Aschenbrenner, A.C.5    Carrera, P.6
  • 7
    • 0028916254 scopus 로고
    • Cactus protein degradation mediates Drosophila dorsal-ventral signaling
    • Retrieved from
    • Belvin M.P., Jin Y., Anderson K.V. Cactus protein degradation mediates Drosophila dorsal-ventral signaling. Genes & Development 1995, 9(7):783-793. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/7705656.
    • (1995) Genes & Development , vol.9 , Issue.7 , pp. 783-793
    • Belvin, M.P.1    Jin, Y.2    Anderson, K.V.3
  • 8
    • 84859808755 scopus 로고    scopus 로고
    • Dual role for Insulin/TOR signaling in the control of hematopoietic progenitor maintenance in Drosophila
    • Benmimoun B., Polesello C., Waltzer L., Haenlin M. Dual role for Insulin/TOR signaling in the control of hematopoietic progenitor maintenance in Drosophila. Development (Cambridge, England) 2012, 139(10):1713-1717. 10.1242/dev.080259.
    • (2012) Development (Cambridge, England) , vol.139 , Issue.10 , pp. 1713-1717
    • Benmimoun, B.1    Polesello, C.2    Waltzer, L.3    Haenlin, M.4
  • 9
    • 9244251126 scopus 로고    scopus 로고
    • Function of the drosophila pattern-recognition receptor PGRP-SD in the detection of Gram-positive bacteria
    • Bischoff V., Vignal C., Boneca I.G., Michel T., Hoffmann J.A., Royet J. Function of the drosophila pattern-recognition receptor PGRP-SD in the detection of Gram-positive bacteria. Nature Immunology 2004, 5(11):1175-1180. 10.1038/ni1123.
    • (2004) Nature Immunology , vol.5 , Issue.11 , pp. 1175-1180
    • Bischoff, V.1    Vignal, C.2    Boneca, I.G.3    Michel, T.4    Hoffmann, J.A.5    Royet, J.6
  • 10
    • 84865108178 scopus 로고    scopus 로고
    • Peptidoglycan sensing by the receptor PGRP-LE in the Drosophila gut induces immune responses to infectious bacteria and tolerance to microbiota
    • Bosco-Drayon V., Poidevin M., Boneca I.G., Narbonne-Reveau K., Royet J., Charroux B. Peptidoglycan sensing by the receptor PGRP-LE in the Drosophila gut induces immune responses to infectious bacteria and tolerance to microbiota. Cell Host & Microbe 2012, 12(2):153-165. 10.1016/j.chom.2012.06.002.
    • (2012) Cell Host & Microbe , vol.12 , Issue.2 , pp. 153-165
    • Bosco-Drayon, V.1    Poidevin, M.2    Boneca, I.G.3    Narbonne-Reveau, K.4    Royet, J.5    Charroux, B.6
  • 13
    • 79953061608 scopus 로고    scopus 로고
    • Human TLRs and IL-1Rs in host defense: Natural insights from evolutionary, epidemiological, and clinical genetics
    • Casanova J.-L., Abel L., Quintana-Murci L. Human TLRs and IL-1Rs in host defense: Natural insights from evolutionary, epidemiological, and clinical genetics. Annual Review of Immunology 2011, 29(2010):447-491. 10.1146/annurev-immunol-030409-101335.
    • (2011) Annual Review of Immunology , vol.29 , Issue.2010 , pp. 447-491
    • Casanova, J.-L.1    Abel, L.2    Quintana-Murci, L.3
  • 15
    • 33645360264 scopus 로고    scopus 로고
    • Drosophila melanogaster as a facile model for large-scale studies of virulence mechanisms and antifungal drug efficacy in Candida species
    • Chamilos G., Lionakis M.S., Lewis R.E., Lopez-Ribot J.L., Saville S.P., Albert N.D., et al. Drosophila melanogaster as a facile model for large-scale studies of virulence mechanisms and antifungal drug efficacy in Candida species. The Journal of Infectious Diseases 2006, 193(7):1014-1022. 10.1086/500950.
    • (2006) The Journal of Infectious Diseases , vol.193 , Issue.7 , pp. 1014-1022
    • Chamilos, G.1    Lionakis, M.S.2    Lewis, R.E.3    Lopez-Ribot, J.L.4    Saville, S.P.5    Albert, N.D.6
  • 16
    • 67649878194 scopus 로고    scopus 로고
    • Elimination of plasmatocytes by targeted apoptosis reveals their role in multiple aspects of the Drosophila immune response
    • Charroux B., Royet J. Elimination of plasmatocytes by targeted apoptosis reveals their role in multiple aspects of the Drosophila immune response. Proceedings of the National Academy of Sciences of the United States of America 2009, 106(24):9797-9802. 10.1073/pnas.0903971106.
    • (2009) Proceedings of the National Academy of Sciences of the United States of America , vol.106 , Issue.24 , pp. 9797-9802
    • Charroux, B.1    Royet, J.2
  • 17
    • 80053979202 scopus 로고    scopus 로고
    • Multiple TGF-β superfamily signals modulate the adult Drosophila immune response
    • Clark R.I., Woodcock K.J., Geissmann F., Trouillet C., Dionne M.S. Multiple TGF-β superfamily signals modulate the adult Drosophila immune response. Current Biology: CB 2011, 21(19):1672-1677. 10.1016/j.cub.2011.08.048.
    • (2011) Current Biology: CB , vol.21 , Issue.19 , pp. 1672-1677
    • Clark, R.I.1    Woodcock, K.J.2    Geissmann, F.3    Trouillet, C.4    Dionne, M.S.5
  • 18
    • 79959668886 scopus 로고    scopus 로고
    • Drosophila: A model for studying genetic and molecular aspects of haematopoiesis and associated leukaemias
    • Crozatier M., Vincent A. Drosophila: A model for studying genetic and molecular aspects of haematopoiesis and associated leukaemias. Disease Models & Mechanisms 2011, 4(4):439-445. 10.1242/dmm.007351.
    • (2011) Disease Models & Mechanisms , vol.4 , Issue.4 , pp. 439-445
    • Crozatier, M.1    Vincent, A.2
  • 19
    • 0032033030 scopus 로고    scopus 로고
    • Proteolytic processing of the Drosophila Spätzle protein by easter generates a dimeric NGF-like molecule with ventralising activity
    • Retrieved from
    • DeLotto Y., DeLotto R. Proteolytic processing of the Drosophila Spätzle protein by easter generates a dimeric NGF-like molecule with ventralising activity. Mechanisms of Development 1998, 72(1-2):141-148. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/9533958.
    • (1998) Mechanisms of Development , vol.72 , Issue.1-2 , pp. 141-148
    • DeLotto, Y.1    DeLotto, R.2
  • 21
    • 33750023633 scopus 로고    scopus 로고
    • Akt and FOXO dysregulation contribute to infection-induced wasting in Drosophila
    • Dionne M.S., Pham L.N., Shirasu-Hiza M., Schneider D.S. Akt and FOXO dysregulation contribute to infection-induced wasting in Drosophila. Current Biology: CB 2006, 16(20):1977-1985. 10.1016/j.cub.2006.08.052.
    • (2006) Current Biology: CB , vol.16 , Issue.20 , pp. 1977-1985
    • Dionne, M.S.1    Pham, L.N.2    Shirasu-Hiza, M.3    Schneider, D.S.4
  • 22
    • 84867657982 scopus 로고    scopus 로고
    • Anopheles NF-κB-regulated splicing factors direct pathogen-specific repertoires of the hypervariable pattern recognition receptor AgDscam
    • Dong Y., Cirimotich C.M., Pike A., Chandra R., Dimopoulos G. Anopheles NF-κB-regulated splicing factors direct pathogen-specific repertoires of the hypervariable pattern recognition receptor AgDscam. Cell Host & Microbe 2012, 12(4):521-530. 10.1016/j.chom.2012.09.004.
    • (2012) Cell Host & Microbe , vol.12 , Issue.4 , pp. 521-530
    • Dong, Y.1    Cirimotich, C.M.2    Pike, A.3    Chandra, R.4    Dimopoulos, G.5
  • 23
    • 52549093726 scopus 로고    scopus 로고
    • Sensing of "danger signals" and pathogen-associated molecular patterns defines binary signaling pathways "upstream" of Toll
    • El Chamy L., Leclerc V., Caldelari I., Reichhart J.-M. Sensing of "danger signals" and pathogen-associated molecular patterns defines binary signaling pathways "upstream" of Toll. Nature Immunology 2008, 9(10):1165-1170. 10.1038/ni.1643.
    • (2008) Nature Immunology , vol.9 , Issue.10 , pp. 1165-1170
    • El Chamy, L.1    Leclerc, V.2    Caldelari, I.3    Reichhart, J.-M.4
  • 25
    • 69249212242 scopus 로고    scopus 로고
    • The Drosophila hindgut lacks constitutively active adult stem cells but proliferates in response to tissue damage
    • Fox D.T., Spradling A.C. The Drosophila hindgut lacks constitutively active adult stem cells but proliferates in response to tissue damage. Cell Stem Cell 2009, 5(3):290-297. 10.1016/j.stem.2009.06.003.
    • (2009) Cell Stem Cell , vol.5 , Issue.3 , pp. 290-297
    • Fox, D.T.1    Spradling, A.C.2
  • 26
    • 47249114405 scopus 로고    scopus 로고
    • Structural insight into the mechanism of activation of the Toll receptor by the dimeric ligand Spätzle
    • Gangloff M., Murali A., Xiong J., Arnot C.J., Weber A.N., Sandercock A.M., et al. Structural insight into the mechanism of activation of the Toll receptor by the dimeric ligand Spätzle. The Journal of Biological Chemistry 2008, 283(21):14629-14635. 10.1074/jbc.M800112200.
    • (2008) The Journal of Biological Chemistry , vol.283 , Issue.21 , pp. 14629-14635
    • Gangloff, M.1    Murali, A.2    Xiong, J.3    Arnot, C.J.4    Weber, A.N.5    Sandercock, A.M.6
  • 27
    • 18044400563 scopus 로고    scopus 로고
    • Drosophila immune deficiency (IMD) is a death domain protein that activates antibacterial defense and can promote apoptosis
    • Retrieved from
    • Georgel P., Naitza S., Kappler C., Ferrandon D., Zachary D., Swimmer C., et al. Drosophila immune deficiency (IMD) is a death domain protein that activates antibacterial defense and can promote apoptosis. Developmental Cell 2001, 1(4):503-514. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/11703941.
    • (2001) Developmental Cell , vol.1 , Issue.4 , pp. 503-514
    • Georgel, P.1    Naitza, S.2    Kappler, C.3    Ferrandon, D.4    Zachary, D.5    Swimmer, C.6
  • 28
    • 79959661948 scopus 로고    scopus 로고
    • Pathogen and host factors are needed to provoke a systemic host response to gastrointestinal infection of Drosophila larvae by Candida albicans
    • Glittenberg M.T., Kounatidis I., Christensen D., Kostov M., Kimber S., Roberts I., et al. Pathogen and host factors are needed to provoke a systemic host response to gastrointestinal infection of Drosophila larvae by Candida albicans. Disease Models & Mechanisms 2011, 4(4):515-525. 10.1242/dmm.006627.
    • (2011) Disease Models & Mechanisms , vol.4 , Issue.4 , pp. 515-525
    • Glittenberg, M.T.1    Kounatidis, I.2    Christensen, D.3    Kostov, M.4    Kimber, S.5    Roberts, I.6
  • 29
    • 79959628056 scopus 로고    scopus 로고
    • Wild-type Drosophila melanogaster as an alternative model system for investigating the pathogenicity of Candida albicans
    • Glittenberg M.T., Silas S., MacCallum D.M., Gow N.A.R., Ligoxygakis P. Wild-type Drosophila melanogaster as an alternative model system for investigating the pathogenicity of Candida albicans. Disease Models & Mechanisms 2011, 4(4):504-514. 10.1242/dmm.006619.
    • (2011) Disease Models & Mechanisms , vol.4 , Issue.4 , pp. 504-514
    • Glittenberg, M.T.1    Silas, S.2    MacCallum, D.M.3    Gow, N.A.R.4    Ligoxygakis, P.5
  • 30
    • 0345731463 scopus 로고    scopus 로고
    • Dual activation of the Drosophila toll pathway by two pattern recognition receptors
    • Gobert V., Gottar M., Matskevich A.A., Rutschmann S., Royet J., Belvin M., et al. Dual activation of the Drosophila toll pathway by two pattern recognition receptors. Science (New York, N.Y.) 2003, 302(5653):2126-2130. 10.1126/science.1085432.
    • (2003) Science (New York, N.Y.) , vol.302 , Issue.5653 , pp. 2126-2130
    • Gobert, V.1    Gottar, M.2    Matskevich, A.A.3    Rutschmann, S.4    Royet, J.5    Belvin, M.6
  • 31
    • 26944485185 scopus 로고    scopus 로고
    • WntD is a feedback inhibitor of Dorsal/NF-kappaB in Drosophila development and immunity
    • Gordon M.D., Dionne M.S., Schneider D.S., Nusse R. WntD is a feedback inhibitor of Dorsal/NF-kappaB in Drosophila development and immunity. Nature 2005, 437(7059):746-749. 10.1038/nature04073.
    • (2005) Nature , vol.437 , Issue.7059 , pp. 746-749
    • Gordon, M.D.1    Dionne, M.S.2    Schneider, D.S.3    Nusse, R.4
  • 32
    • 84869108498 scopus 로고    scopus 로고
    • Molecular evolution and structural features of IRAK family members
    • Gosu V., Basith S., Durai P., Choi S. Molecular evolution and structural features of IRAK family members. PLoS One 2012, 7(11):e49771. 10.1371/journal.pone.0049771.
    • (2012) PLoS One , vol.7 , Issue.11
    • Gosu, V.1    Basith, S.2    Durai, P.3    Choi, S.4
  • 33
    • 33845666959 scopus 로고    scopus 로고
    • Dual detection of fungal infections in Drosophila via recognition of glucans and sensing of virulence factors
    • Gottar M., Gobert V., Matskevich A.A., Reichhart J.-M., Wang C., Butt T.M., et al. Dual detection of fungal infections in Drosophila via recognition of glucans and sensing of virulence factors. Cell 2006, 127(7):1425-1437. 10.1016/j.cell.2006.10.046.
    • (2006) Cell , vol.127 , Issue.7 , pp. 1425-1437
    • Gottar, M.1    Gobert, V.2    Matskevich, A.A.3    Reichhart, J.-M.4    Wang, C.5    Butt, T.M.6
  • 35
    • 56749158645 scopus 로고    scopus 로고
    • Antimicrobial defense and persistent infection in insects
    • Haine E.R., Moret Y., Siva-Jothy M.T., Rolff J. Antimicrobial defense and persistent infection in insects. Science (New York, N.Y.) 2008, 322(5905):1257-1259. 10.1126/science.1165265.
    • (2008) Science (New York, N.Y.) , vol.322 , Issue.5905 , pp. 1257-1259
    • Haine, E.R.1    Moret, Y.2    Siva-Jothy, M.T.3    Rolff, J.4
  • 36
    • 84865682920 scopus 로고    scopus 로고
    • Self-organized shuttling: Generating sharp dorsoventral polarity in the early Drosophila embryo
    • Haskel-Ittah M., Ben-Zvi D., Branski-Arieli M., Schejter E.D., Shilo B.-Z., Barkai N. Self-organized shuttling: Generating sharp dorsoventral polarity in the early Drosophila embryo. Cell 2012, 150(5):1016-1028. 10.1016/j.cell.2012.06.044.
    • (2012) Cell , vol.150 , Issue.5 , pp. 1016-1028
    • Haskel-Ittah, M.1    Ben-Zvi, D.2    Branski-Arieli, M.3    Schejter, E.D.4    Shilo, B.-Z.5    Barkai, N.6
  • 38
    • 0033120081 scopus 로고    scopus 로고
    • Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: Evidence for TLR4 as the Lps gene product
    • Retrieved from
    • Hoshino K., Takeuchi O., Kawai T., Sanjo H., Ogawa T., Takeda Y., et al. Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: Evidence for TLR4 as the Lps gene product. Journal of Immunology (Baltimore, Md.: 1950) 1999, 162(7):3749-3752. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/10201887.
    • (1999) Journal of Immunology (Baltimore, Md.: 1950) , vol.162 , Issue.7 , pp. 3749-3752
    • Hoshino, K.1    Takeuchi, O.2    Kawai, T.3    Sanjo, H.4    Ogawa, T.5    Takeda, Y.6
  • 42
    • 14044272776 scopus 로고    scopus 로고
    • New insights into Drosophila larval haemocyte functions through genome-wide analysis
    • Irving P., Ubeda J.-M., Doucet D., Troxler L., Lagueux M., Zachary D., et al. New insights into Drosophila larval haemocyte functions through genome-wide analysis. Cellular Microbiology 2005, 7(3):335-350. 10.1111/j.1462-5822.2004.00462.x.
    • (2005) Cellular Microbiology , vol.7 , Issue.3 , pp. 335-350
    • Irving, P.1    Ubeda, J.-M.2    Doucet, D.3    Troxler, L.4    Lagueux, M.5    Zachary, D.6
  • 43
    • 0024955886 scopus 로고
    • Approaching the asymptote? Evolution and revolution in immunology
    • Retrieved from
    • Janeway C.A. Approaching the asymptote? Evolution and revolution in immunology. Cold Spring Harbor Symposia on Quantitative Biology 1989, 54(Pt 1):1-13. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/2700931.
    • (1989) Cold Spring Harbor Symposia on Quantitative Biology , vol.54 , Issue.PART 1 , pp. 1-13
    • Janeway, C.A.1
  • 44
    • 0036212849 scopus 로고    scopus 로고
    • Innate immune recognition
    • Janeway C.A., Medzhitov R. Innate immune recognition. Annual Review of Immunology 2002, 20(2):197-216. 10.1146/annurev.immunol.20.083001.084359.
    • (2002) Annual Review of Immunology , vol.20 , Issue.2 , pp. 197-216
    • Janeway, C.A.1    Medzhitov, R.2
  • 45
    • 29744438644 scopus 로고    scopus 로고
    • A Spätzle-processing enzyme required for toll signaling activation in Drosophila innate immunity
    • Jang I.-H., Chosa N., Kim S.-H., Nam H.-J., Lemaitre B., Ochiai M., et al. A Spätzle-processing enzyme required for toll signaling activation in Drosophila innate immunity. Developmental Cell 2006, 10(1):45-55. 10.1016/j.devcel.2005.11.013.
    • (2006) Developmental Cell , vol.10 , Issue.1 , pp. 45-55
    • Jang, I.-H.1    Chosa, N.2    Kim, S.-H.3    Nam, H.-J.4    Lemaitre, B.5    Ochiai, M.6
  • 46
    • 80455173895 scopus 로고    scopus 로고
    • Intestinal stem cells in the adult Drosophila midgut
    • Jiang H., Edgar B.A. Intestinal stem cells in the adult Drosophila midgut. Experimental Cell Research 2011, 317(19):2780-2788. 10.1016/j.yexcr.2011.07.020.
    • (2011) Experimental Cell Research , vol.317 , Issue.19 , pp. 2780-2788
    • Jiang, H.1    Edgar, B.A.2
  • 49
    • 33646037067 scopus 로고    scopus 로고
    • Drosophila immunity: A large-scale in vivo RNAi screen identifies five serine proteases required for Toll activation
    • Kambris Z., Brun S., Jang I.-H., Nam H.-J., Romeo Y., Takahashi K., et al. Drosophila immunity: A large-scale in vivo RNAi screen identifies five serine proteases required for Toll activation. Current Biology: CB 2006, 16(8):808-813. 10.1016/j.cub.2006.03.020.
    • (2006) Current Biology: CB , vol.16 , Issue.8 , pp. 808-813
    • Kambris, Z.1    Brun, S.2    Jang, I.-H.3    Nam, H.-J.4    Romeo, Y.5    Takahashi, K.6
  • 50
    • 2442456719 scopus 로고    scopus 로고
    • Monomeric and polymeric gram-negative peptidoglycan but not purified LPS stimulate the Drosophila IMD pathway
    • Retrieved from
    • Kaneko T., Goldman W.E., Mellroth P., Steiner H., Fukase K., Kusumoto S., et al. Monomeric and polymeric gram-negative peptidoglycan but not purified LPS stimulate the Drosophila IMD pathway. Immunity 2004, 20(5):637-649. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/15142531.
    • (2004) Immunity , vol.20 , Issue.5 , pp. 637-649
    • Kaneko, T.1    Goldman, W.E.2    Mellroth, P.3    Steiner, H.4    Fukase, K.5    Kusumoto, S.6
  • 51
    • 33745225236 scopus 로고    scopus 로고
    • PGRP-LC and PGRP-LE have essential yet distinct functions in the drosophila immune response to monomeric DAP-type peptidoglycan
    • Kaneko T., Yano T., Aggarwal K., Lim J.-H., Ueda K., Oshima Y., et al. PGRP-LC and PGRP-LE have essential yet distinct functions in the drosophila immune response to monomeric DAP-type peptidoglycan. Nature Immunology 2006, 7(7):715-723. 10.1038/ni1356.
    • (2006) Nature Immunology , vol.7 , Issue.7 , pp. 715-723
    • Kaneko, T.1    Yano, T.2    Aggarwal, K.3    Lim, J.-H.4    Ueda, K.5    Oshima, Y.6
  • 52
    • 79958181684 scopus 로고    scopus 로고
    • Dynamic coordination of innate immune signaling and insulin signaling regulates systemic responses to localized DNA damage
    • Karpac J., Younger A., Jasper H. Dynamic coordination of innate immune signaling and insulin signaling regulates systemic responses to localized DNA damage. Developmental Cell 2011, 20(6):841-854. 10.1016/j.devcel.2011.05.011.
    • (2011) Developmental Cell , vol.20 , Issue.6 , pp. 841-854
    • Karpac, J.1    Younger, A.2    Jasper, H.3
  • 53
    • 84876377610 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa disrupts Caenorhabditis elegans iron homeostasis, causing a hypoxic response and death
    • A 17
    • Kirienko N.V., Kirienko D.R., Larkins-Ford J., Wählby C., Ruvkun G., Ausubel F.M. Pseudomonas aeruginosa disrupts Caenorhabditis elegans iron homeostasis, causing a hypoxic response and death. Cell Host Microbe 2013 Apr 17, 13(4):406-416. 10.1016/j.chom.2013.03.003.
    • (2013) Cell Host Microbe , vol.13 , Issue.4 , pp. 406-416
    • Kirienko, N.V.1    Kirienko, D.R.2    Larkins-Ford, J.3    Wählby, C.4    Ruvkun, G.5    Ausubel, F.M.6
  • 55
    • 27144475536 scopus 로고    scopus 로고
    • Inhibitor of apoptosis 2 and TAK1-binding protein are components of the Drosophila Imd pathway
    • Kleino A., Valanne S., Ulvila J., Kallio J., Myllymäki H., Enwald H., et al. Inhibitor of apoptosis 2 and TAK1-binding protein are components of the Drosophila Imd pathway. The EMBO Journal 2005, 24(19):3423-3434. 10.1038/sj.emboj.7600807.
    • (2005) The EMBO Journal , vol.24 , Issue.19 , pp. 3423-3434
    • Kleino, A.1    Valanne, S.2    Ulvila, J.3    Kallio, J.4    Myllymäki, H.5    Enwald, H.6
  • 56
    • 84864204550 scopus 로고    scopus 로고
    • Drosophila as a model system to unravel the layers of innate immunity to infection
    • Kounatidis I., Ligoxygakis P. Drosophila as a model system to unravel the layers of innate immunity to infection. Open Biology 2012, 2(5):120075. 10.1098/rsob.120075.
    • (2012) Open Biology , vol.2 , Issue.5 , pp. 120075
    • Kounatidis, I.1    Ligoxygakis, P.2
  • 57
    • 34948904198 scopus 로고    scopus 로고
    • Selective predisposition to bacterial infections in IRAK-4-deficient children: IRAK-4-dependent TLRs are otherwise redundant in protective immunity
    • Ku C.-L., Von Bernuth H., Picard C., Zhang S.-Y., Chang H.-H., Yang K., et al. Selective predisposition to bacterial infections in IRAK-4-deficient children: IRAK-4-dependent TLRs are otherwise redundant in protective immunity. The Journal of Experimental Medicine 2007, 204(10):2407-2422. 10.1084/jem.20070628.
    • (2007) The Journal of Experimental Medicine , vol.204 , Issue.10 , pp. 2407-2422
    • Ku, C.-L.1    Von Bernuth, H.2    Picard, C.3    Zhang, S.-Y.4    Chang, H.-H.5    Yang, K.6
  • 58
    • 65649120359 scopus 로고    scopus 로고
    • Increased virulence of Zygomycetes organisms following exposure to voriconazole: A study involving fly and murine models of zygomycosis
    • Lamaris G.A., Ben-Ami R., Lewis R.E., Chamilos G., Samonis G., Kontoyiannis D.P. Increased virulence of Zygomycetes organisms following exposure to voriconazole: A study involving fly and murine models of zygomycosis. The Journal of Infectious Diseases 2009, 199(9):1399-1406. 10.1086/597615.
    • (2009) The Journal of Infectious Diseases , vol.199 , Issue.9 , pp. 1399-1406
    • Lamaris, G.A.1    Ben-Ami, R.2    Lewis, R.E.3    Chamilos, G.4    Samonis, G.5    Kontoyiannis, D.P.6
  • 59
    • 0030595339 scopus 로고    scopus 로고
    • The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults
    • Retrieved from
    • Lemaitre B., Nicolas E., Michaut L., Reichhart J.M., Hoffmann J.A. The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell 1996, 86(6):973-983. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/22611248.
    • (1996) Cell , vol.86 , Issue.6 , pp. 973-983
    • Lemaitre, B.1    Nicolas, E.2    Michaut, L.3    Reichhart, J.M.4    Hoffmann, J.A.5
  • 60
    • 0031446642 scopus 로고    scopus 로고
    • Drosophila host defense: Differential induction of antimicrobial peptide genes after infection by various classes of microorganisms
    • Retrieved from
    • Lemaitre B., Reichhart J.M., Hoffmann J.A. Drosophila host defense: Differential induction of antimicrobial peptide genes after infection by various classes of microorganisms. Proceedings of the National Academy of Sciences of the United States of America 1997, 94(26):14614-14619. Retrieved from. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=25070&tool=pmcentrez&rendertype=abstract.
    • (1997) Proceedings of the National Academy of Sciences of the United States of America , vol.94 , Issue.26 , pp. 14614-14619
    • Lemaitre, B.1    Reichhart, J.M.2    Hoffmann, J.A.3
  • 61
    • 0033106265 scopus 로고    scopus 로고
    • Signal transduction by a protease cascade
    • Retrieved from
    • LeMosy E.K., Hong C.C., Hashimoto C. Signal transduction by a protease cascade. Trends in Cell Biology 1999, 9(3):102-107. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/10201075.
    • (1999) Trends in Cell Biology , vol.9 , Issue.3 , pp. 102-107
    • LeMosy, E.K.1    Hong, C.C.2    Hashimoto, C.3
  • 62
    • 40849111159 scopus 로고    scopus 로고
    • Crystal structure of Drosophila PGRP-SD suggests binding to DAP-type but not lysine-type peptidoglycan
    • Leone P., Bischoff V., Kellenberger C., Hetru C., Royet J., Roussel A. Crystal structure of Drosophila PGRP-SD suggests binding to DAP-type but not lysine-type peptidoglycan. Molecular Immunology 2008, 45(9):2521-2530. 10.1016/j.molimm.2008.01.015.
    • (2008) Molecular Immunology , vol.45 , Issue.9 , pp. 2521-2530
    • Leone, P.1    Bischoff, V.2    Kellenberger, C.3    Hetru, C.4    Royet, J.5    Roussel, A.6
  • 63
    • 0038664357 scopus 로고    scopus 로고
    • The Drosophila immune system detects bacteria through specific peptidoglycan recognition
    • Leulier F., Parquet C., Pili-Floury S., Ryu J.-H., Caroff M., Lee W.-J., et al. The Drosophila immune system detects bacteria through specific peptidoglycan recognition. Nature Immunology 2003, 4(5):478-484. 10.1038/ni922.
    • (2003) Nature Immunology , vol.4 , Issue.5 , pp. 478-484
    • Leulier, F.1    Parquet, C.2    Pili-Floury, S.3    Ryu, J.-H.4    Caroff, M.5    Lee, W.-J.6
  • 64
    • 0034305744 scopus 로고    scopus 로고
    • The Drosophila caspase Dredd is required to resist gram-negative bacterial infection
    • Leulier F., Rodriguez A., Khush R.S., Abrams J.M., Lemaitre B. The Drosophila caspase Dredd is required to resist gram-negative bacterial infection. EMBO Reports 2000, 1(4):353-358. 10.1093/embo-reports/kvd073.
    • (2000) EMBO Reports , vol.1 , Issue.4 , pp. 353-358
    • Leulier, F.1    Rodriguez, A.2    Khush, R.S.3    Abrams, J.M.4    Lemaitre, B.5
  • 65
    • 0037172656 scopus 로고    scopus 로고
    • Inducible expression of double-stranded RNA reveals a role for dFADD in the regulation of the antibacterial response in Drosophila adults
    • Retrieved from
    • Leulier F., Vidal S., Saigo K., Ueda R., Lemaitre B. Inducible expression of double-stranded RNA reveals a role for dFADD in the regulation of the antibacterial response in Drosophila adults. Current Biology: CB 2002, 12(12):996-1000. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/12123572.
    • (2002) Current Biology: CB , vol.12 , Issue.12 , pp. 996-1000
    • Leulier, F.1    Vidal, S.2    Saigo, K.3    Ueda, R.4    Lemaitre, B.5
  • 66
    • 0033578917 scopus 로고    scopus 로고
    • Constitutive activation of toll-mediated antifungal defense in serpin-deficient Drosophila
    • Retrieved from
    • Levashina E.A., Langley E., Green C., Gubb D., Ashburner M., Hoffmann J.A., et al. Constitutive activation of toll-mediated antifungal defense in serpin-deficient Drosophila. Science (New York, N.Y.) 1999, 285(5435):1917-1919. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/104893720.
    • (1999) Science (New York, N.Y.) , vol.285 , Issue.5435 , pp. 1917-1919
    • Levashina, E.A.1    Langley, E.2    Green, C.3    Gubb, D.4    Ashburner, M.5    Hoffmann, J.A.6
  • 67
    • 48649085941 scopus 로고    scopus 로고
    • PIMS modulates immune tolerance by negatively regulating Drosophila innate immune signaling
    • Lhocine N., Ribeiro P.S., Buchon N., Wepf A., Wilson R., Tenev T., et al. PIMS modulates immune tolerance by negatively regulating Drosophila innate immune signaling. Cell Host & Microbe 2008, 4(2):147-158. 10.1016/j.chom.2008.07.004.
    • (2008) Cell Host & Microbe , vol.4 , Issue.2 , pp. 147-158
    • Lhocine, N.1    Ribeiro, P.S.2    Buchon, N.3    Wepf, A.4    Wilson, R.5    Tenev, T.6
  • 68
    • 33745712561 scopus 로고    scopus 로고
    • Prevalence of local immune response against oral infection in a Drosophila/Pseudomonas infection model
    • Liehl P., Blight M., Vodovar N., Boccard F., Lemaitre B. Prevalence of local immune response against oral infection in a Drosophila/Pseudomonas infection model. PLoS Pathogens 2006, 2(6):e56. 10.1371/journal.ppat.0020056.
    • (2006) PLoS Pathogens , vol.2 , Issue.6
    • Liehl, P.1    Blight, M.2    Vodovar, N.3    Boccard, F.4    Lemaitre, B.5
  • 69
    • 0037025213 scopus 로고    scopus 로고
    • Activation of Drosophila Toll during fungal infection by a blood serine protease
    • Ligoxygakis P., Pelte N., Hoffmann J.A., Reichhart J.-M. Activation of Drosophila Toll during fungal infection by a blood serine protease. Science (New York, N.Y.) 2002, 297(5578):114-116. 10.1126/science.1072391.
    • (2002) Science (New York, N.Y.) , vol.297 , Issue.5578 , pp. 114-116
    • Ligoxygakis, P.1    Pelte, N.2    Hoffmann, J.A.3    Reichhart, J.-M.4
  • 70
    • 0037011189 scopus 로고    scopus 로고
    • A serpin mutant links Toll activation to melanization in the host defence of Drosophila
    • Retrieved from
    • Ligoxygakis P., Pelte N., Ji C., Leclerc V., Duvic B., Belvin M., et al. A serpin mutant links Toll activation to melanization in the host defence of Drosophila. The EMBO Journal 2002, 21(23):6330-6337. Retrieved from. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=136964&tool=pmcentrez&rendertype=abstract.
    • (2002) The EMBO Journal , vol.21 , Issue.23 , pp. 6330-6337
    • Ligoxygakis, P.1    Pelte, N.2    Ji, C.3    Leclerc, V.4    Duvic, B.5    Belvin, M.6
  • 71
    • 0034677596 scopus 로고    scopus 로고
    • A beta 1,3-glucan recognition protein from an insect, Manduca sexta, agglutinates microorganisms and activates the phenoloxidase cascade
    • Ma C. A beta 1,3-glucan recognition protein from an insect, Manduca sexta, agglutinates microorganisms and activates the phenoloxidase cascade. Journal of Biological Chemistry 2000, 275(11):7505-7514. 10.1074/jbc.275.11.7505.
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.11 , pp. 7505-7514
    • Ma, C.1
  • 72
    • 0033564614 scopus 로고    scopus 로고
    • A mosaic analysis in Drosophila fat body cells of the control of antimicrobial peptide genes by the Rel proteins Dorsal and DIF
    • Manfruelli P., Reichhart J.M., Steward R., Hoffmann J.A., Lemaitre B. A mosaic analysis in Drosophila fat body cells of the control of antimicrobial peptide genes by the Rel proteins Dorsal and DIF. The EMBO Journal 1999, 18(12):3380-3391. 10.1093/emboj/18.12.3380.
    • (1999) The EMBO Journal , vol.18 , Issue.12 , pp. 3380-3391
    • Manfruelli, P.1    Reichhart, J.M.2    Steward, R.3    Hoffmann, J.A.4    Lemaitre, B.5
  • 73
    • 84859985764 scopus 로고    scopus 로고
    • Phosphoinositide binding by the Toll adaptor dMyD88 controls antibacterial responses in Drosophila
    • Marek L.R., Kagan J.C. Phosphoinositide binding by the Toll adaptor dMyD88 controls antibacterial responses in Drosophila. Immunity 2012, 36(4):612-622. 10.1016/j.immuni.2012.01.019.
    • (2012) Immunity , vol.36 , Issue.4 , pp. 612-622
    • Marek, L.R.1    Kagan, J.C.2
  • 74
    • 66949122854 scopus 로고    scopus 로고
    • Approaching the asymptote: 20 years later
    • Medzhitov R. Approaching the asymptote: 20 years later. Immunity 2009, 30(6):766-775. 10.1016/j.immuni.2009.06.004.
    • (2009) Immunity , vol.30 , Issue.6 , pp. 766-775
    • Medzhitov, R.1
  • 75
    • 0030831210 scopus 로고    scopus 로고
    • A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
    • Medzhitov R., Preston-Hurlburt P., Janeway C.A. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 1997, 388(6640):394-397. 10.1038/41131.
    • (1997) Nature , vol.388 , Issue.6640 , pp. 394-397
    • Medzhitov, R.1    Preston-Hurlburt, P.2    Janeway, C.A.3
  • 76
    • 84862189464 scopus 로고    scopus 로고
    • Ubiquitylation of the initiator caspase DREDD is required for innate immune signalling
    • Meinander A., Runchel C., Tenev T., Chen L., Kim C.-H., Ribeiro P.S., et al. Ubiquitylation of the initiator caspase DREDD is required for innate immune signalling. The EMBO Journal 2012, 31(12):2770-2783. 10.1038/emboj.2012.121.
    • (2012) The EMBO Journal , vol.31 , Issue.12 , pp. 2770-2783
    • Meinander, A.1    Runchel, C.2    Tenev, T.3    Chen, L.4    Kim, C.-H.5    Ribeiro, P.S.6
  • 77
    • 0035856990 scopus 로고    scopus 로고
    • Drosophila Toll is activated by Gram-positive bacteria through a circulating peptidoglycan recognition protein
    • Michel T., Reichhart J.M., Hoffmann J.A., Royet J. Drosophila Toll is activated by Gram-positive bacteria through a circulating peptidoglycan recognition protein. Nature 2001, 414(6865):756-759. 10.1038/414756a.
    • (2001) Nature , vol.414 , Issue.6865 , pp. 756-759
    • Michel, T.1    Reichhart, J.M.2    Hoffmann, J.A.3    Royet, J.4
  • 78
    • 70350417515 scopus 로고    scopus 로고
    • The N-terminal domain of Drosophila Gram-negative binding protein 3 (GNBP3) defines a novel family of fungal pattern recognition receptors
    • Mishima Y., Quintin J., Aimanianda V., Kellenberger C., Coste F., Clavaud C., et al. The N-terminal domain of Drosophila Gram-negative binding protein 3 (GNBP3) defines a novel family of fungal pattern recognition receptors. The Journal of Biological Chemistry 2009, 284(42):28687-28697. 10.1074/jbc.M109.034587.
    • (2009) The Journal of Biological Chemistry , vol.284 , Issue.42 , pp. 28687-28697
    • Mishima, Y.1    Quintin, J.2    Aimanianda, V.3    Kellenberger, C.4    Coste, F.5    Clavaud, C.6
  • 79
    • 0034936975 scopus 로고    scopus 로고
    • Spätzle regulates the shape of the Dorsal gradient in the Drosophila embryo
    • Retrieved from
    • Morisato D. Spätzle regulates the shape of the Dorsal gradient in the Drosophila embryo. Development (Cambridge, England) 2001, 128(12):2309-2319. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/11493550.
    • (2001) Development (Cambridge, England) , vol.128 , Issue.12 , pp. 2309-2319
    • Morisato, D.1
  • 80
    • 0036850985 scopus 로고    scopus 로고
    • The Drosophila immune defense against gram-negative infection requires the death protein dFADD
    • Retrieved from
    • Naitza S., Rossé C., Kappler C., Georgel P., Belvin M., Gubb D., et al. The Drosophila immune defense against gram-negative infection requires the death protein dFADD. Immunity 2002, 17(5):575-581. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/12433364.
    • (2002) Immunity , vol.17 , Issue.5 , pp. 575-581
    • Naitza, S.1    Rossé, C.2    Kappler, C.3    Georgel, P.4    Belvin, M.5    Gubb, D.6
  • 81
    • 70349167463 scopus 로고    scopus 로고
    • The role of melanization and cytotoxic by-products in the cellular immune responses of Drosophila against parasitic wasps
    • Nappi A., Poirié M., Carton Y. The role of melanization and cytotoxic by-products in the cellular immune responses of Drosophila against parasitic wasps. Advances in Parasitology 2009, 70:99-121. 10.1016/S0065-308X(09)70004-1.
    • (2009) Advances in Parasitology , vol.70 , pp. 99-121
    • Nappi, A.1    Poirié, M.2    Carton, Y.3
  • 82
    • 84864807751 scopus 로고    scopus 로고
    • Tissue- and ligand-specific sensing of gram-negative infection in Drosophila by PGRP-LC isoforms and PGRP-LE
    • Neyen C., Poidevin M., Roussel A., Lemaitre B. Tissue- and ligand-specific sensing of gram-negative infection in Drosophila by PGRP-LC isoforms and PGRP-LE. Journal of Immunology (Baltimore, Md.: 1950) 2012, 189(4):1886-1897. 10.4049/jimmunol.1201022.
    • (2012) Journal of Immunology (Baltimore, Md.: 1950) , vol.189 , Issue.4 , pp. 1886-1897
    • Neyen, C.1    Poidevin, M.2    Roussel, A.3    Lemaitre, B.4
  • 83
    • 0034681346 scopus 로고    scopus 로고
    • A pattern-recognition protein for beta -1,3-glucan. The binding domain and the cDNA cloning of beta -1,3-glucan recognition protein from the silkworm, Bombyx mori
    • Ochiai M. A pattern-recognition protein for beta -1,3-glucan. The binding domain and the cDNA cloning of beta -1,3-glucan recognition protein from the silkworm, Bombyx mori. Journal of Biological Chemistry 2000, 275(7):4995-5002. 10.1074/jbc.275.7.4995.
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.7 , pp. 4995-5002
    • Ochiai, M.1
  • 84
    • 74749093547 scopus 로고    scopus 로고
    • Caspase-mediated cleavage, IAP binding, and ubiquitination: Linking three mechanisms crucial for Drosophila NF-kappaB signaling
    • Paquette N., Broemer M., Aggarwal K., Chen L., Husson M., Ertürk-Hasdemir D., et al. Caspase-mediated cleavage, IAP binding, and ubiquitination: Linking three mechanisms crucial for Drosophila NF-kappaB signaling. Molecular Cell 2010, 37(2):172-182. 10.1016/j.molcel.2009.12.036.
    • (2010) Molecular Cell , vol.37 , Issue.2 , pp. 172-182
    • Paquette, N.1    Broemer, M.2    Aggarwal, K.3    Chen, L.4    Husson, M.5    Ertürk-Hasdemir, D.6
  • 85
    • 82055177179 scopus 로고    scopus 로고
    • Negative regulation by amidase PGRPs shapes the Drosophila antibacterial response and protects the fly from innocuous infection
    • Paredes J.C., Welchman D.P., Poidevin M., Lemaitre B. Negative regulation by amidase PGRPs shapes the Drosophila antibacterial response and protects the fly from innocuous infection. Immunity 2011, 35(5):770-779. 10.1016/j.immuni.2011.09.018.
    • (2011) Immunity , vol.35 , Issue.5 , pp. 770-779
    • Paredes, J.C.1    Welchman, D.P.2    Poidevin, M.3    Lemaitre, B.4
  • 86
    • 12144288602 scopus 로고    scopus 로고
    • Targeting of TAK1 by the NF-kappa B protein Relish regulates the JNK-mediated immune response in Drosophila
    • Park J.M., Brady H., Ruocco M.G., Sun H., Williams D., Lee S.J., et al. Targeting of TAK1 by the NF-kappa B protein Relish regulates the JNK-mediated immune response in Drosophila. Genes & Development 2004, 18(5):584-594. 10.1101/gad.1168104.
    • (2004) Genes & Development , vol.18 , Issue.5 , pp. 584-594
    • Park, J.M.1    Brady, H.2    Ruocco, M.G.3    Sun, H.4    Williams, D.5    Lee, S.J.6
  • 88
    • 84857993243 scopus 로고    scopus 로고
    • Drosophila Pez acts in Hippo signaling to restrict intestinal stem cell proliferation
    • Poernbacher I., Baumgartner R., Marada S.K., Edwards K., Stocker H. Drosophila Pez acts in Hippo signaling to restrict intestinal stem cell proliferation. Current Biology: CB 2012, 22(5):389-396. 10.1016/j.cub.2012.01.019.
    • (2012) Current Biology: CB , vol.22 , Issue.5 , pp. 389-396
    • Poernbacher, I.1    Baumgartner, R.2    Marada, S.K.3    Edwards, K.4    Stocker, H.5
  • 89
    • 0032509295 scopus 로고    scopus 로고
    • Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
    • Retrieved from
    • Poltorak A., He X., Smirnova I., Liu M.Y., Van Huffel C., Du X., et al. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene. Science (New York, N.Y.) 1998, 282(5396):2085-2088. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/9851930.
    • (1998) Science (New York, N.Y.) , vol.282 , Issue.5396 , pp. 2085-2088
    • Poltorak, A.1    He, X.2    Smirnova, I.3    Liu, M.Y.4    Van Huffel, C.5    Du, X.6
  • 90
    • 0000421694 scopus 로고
    • Fat body
    • Academic, New York, M. Ashburner, T. Wright (Eds.)
    • Rizki T. Fat body. The genetics and biology of Drosophila 1978, 561-599. Academic, New York. M. Ashburner, T. Wright (Eds.).
    • (1978) The genetics and biology of Drosophila , pp. 561-599
    • Rizki, T.1
  • 91
    • 0033711445 scopus 로고    scopus 로고
    • The Rel protein DIF mediates the antifungal but not the antibacterial host defense in Drosophila
    • Retrieved from
    • Rutschmann S., Jung A.C., Hetru C., Reichhart J.M., Hoffmann J.A., Ferrandon D. The Rel protein DIF mediates the antifungal but not the antibacterial host defense in Drosophila. Immunity 2000, 12(5):569-580. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/10843389.
    • (2000) Immunity , vol.12 , Issue.5 , pp. 569-580
    • Rutschmann, S.1    Jung, A.C.2    Hetru, C.3    Reichhart, J.M.4    Hoffmann, J.A.5    Ferrandon, D.6
  • 92
    • 38949153861 scopus 로고    scopus 로고
    • Innate immune homeostasis by the homeobox gene caudal and commensal-gut mutualism in Drosophila
    • Ryu J.-H., Kim S.-H., Lee H.-Y., Bai J.Y., Nam Y.-D., Bae J.-W., et al. Innate immune homeostasis by the homeobox gene caudal and commensal-gut mutualism in Drosophila. Science (New York, N.Y.) 2008, 319(5864):777-782. 10.1126/science.1149357.
    • (2008) Science (New York, N.Y.) , vol.319 , Issue.5864 , pp. 777-782
    • Ryu, J.-H.1    Kim, S.-H.2    Lee, H.-Y.3    Bai, J.Y.4    Nam, Y.-D.5    Bae, J.-W.6
  • 93
    • 71449095250 scopus 로고    scopus 로고
    • Toll-dependent antimicrobial responses in Drosophila larval fat body require Spätzle secreted by haemocytes
    • Shia A.K.H., Glittenberg M., Thompson G., Weber A.N., Reichhart J.-M., Ligoxygakis P. Toll-dependent antimicrobial responses in Drosophila larval fat body require Spätzle secreted by haemocytes. Journal of Cell Science 2009, 122(Pt 24):4505-4515. 10.1242/jcs.049155.
    • (2009) Journal of Cell Science , vol.122 , Issue.PART 24 , pp. 4505-4515
    • Shia, A.K.H.1    Glittenberg, M.2    Thompson, G.3    Weber, A.N.4    Reichhart, J.-M.5    Ligoxygakis, P.6
  • 95
    • 0023619362 scopus 로고
    • Dorsal, an embryonic polarity gene in Drosophila, is homologous to the vertebrate proto-oncogene, c-rel
    • Retrieved from
    • Steward R. Dorsal, an embryonic polarity gene in Drosophila, is homologous to the vertebrate proto-oncogene, c-rel. Science (New York, N.Y.) 1987, 238(4827):692-694. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/3118464.
    • (1987) Science (New York, N.Y.) , vol.238 , Issue.4827 , pp. 692-694
    • Steward, R.1
  • 97
    • 0036141954 scopus 로고    scopus 로고
    • Drosophila MyD88 is required for the response to fungal and Gram-positive bacterial infections
    • Tauszig-Delamasure S., Bilak H., Capovilla M., Hoffmann J.A., Imler J.-L. Drosophila MyD88 is required for the response to fungal and Gram-positive bacterial infections. Nature Immunology 2002, 3(1):91-97. 10.1038/ni747.
    • (2002) Nature Immunology , vol.3 , Issue.1 , pp. 91-97
    • Tauszig-Delamasure, S.1    Bilak, H.2    Capovilla, M.3    Hoffmann, J.A.4    Imler, J.-L.5
  • 98
    • 0028365963 scopus 로고
    • Embryonic origin of hemocytes and their relationship to cell death in Drosophila
    • Retrieved from
    • Tepass U., Fessler L.I., Aziz A., Hartenstein V. Embryonic origin of hemocytes and their relationship to cell death in Drosophila. Development (Cambridge, England) 1994, 120(7):1829-1837. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/7924990.
    • (1994) Development (Cambridge, England) , vol.120 , Issue.7 , pp. 1829-1837
    • Tepass, U.1    Fessler, L.I.2    Aziz, A.3    Hartenstein, V.4
  • 99
    • 72649083654 scopus 로고    scopus 로고
    • The Drosophila ubiquitin-specific protease dUSP36/Scny targets IMD to prevent constitutive immune signaling
    • Thevenon D., Engel E., Avet-Rochex A., Gottar M., Bergeret E., Tricoire H., et al. The Drosophila ubiquitin-specific protease dUSP36/Scny targets IMD to prevent constitutive immune signaling. Cell Host & Microbe 2009, 6(4):309-320. 10.1016/j.chom.2009.09.007.
    • (2009) Cell Host & Microbe , vol.6 , Issue.4 , pp. 309-320
    • Thevenon, D.1    Engel, E.2    Avet-Rochex, A.3    Gottar, M.4    Bergeret, E.5    Tricoire, H.6
  • 100
    • 84864248668 scopus 로고    scopus 로고
    • Gene regulatory networks controlling hematopoietic progenitor niche cell production and differentiation in the Drosophila lymph gland
    • Tokusumi Y., Tokusumi T., Shoue D.A., Schulz R.A. Gene regulatory networks controlling hematopoietic progenitor niche cell production and differentiation in the Drosophila lymph gland. PLoS One 2012, 7(7):e41604. 10.1371/journal.pone.0041604.
    • (2012) PLoS One , vol.7 , Issue.7
    • Tokusumi, Y.1    Tokusumi, T.2    Shoue, D.A.3    Schulz, R.A.4
  • 101
    • 0035208076 scopus 로고    scopus 로고
    • The protein kinase Pelle mediates feedback regulation in the Drosophila Toll signaling pathway
    • Retrieved from
    • Towb P., Bergmann A., Wasserman S.A. The protein kinase Pelle mediates feedback regulation in the Drosophila Toll signaling pathway. Development (Cambridge, England) 2001, 128(23):4729-4736. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/11731453.
    • (2001) Development (Cambridge, England) , vol.128 , Issue.23 , pp. 4729-4736
    • Towb, P.1    Bergmann, A.2    Wasserman, S.A.3
  • 102
    • 77952370155 scopus 로고    scopus 로고
    • Tube Is an IRAK-4 homolog in a Toll pathway adapted for development and immunity
    • Towb P., Sun H., Wasserman S.A. Tube Is an IRAK-4 homolog in a Toll pathway adapted for development and immunity. Journal of Innate Immunity 2009, 1(4):309-321. 10.1159/000200773.
    • (2009) Journal of Innate Immunity , vol.1 , Issue.4 , pp. 309-321
    • Towb, P.1    Sun, H.2    Wasserman, S.A.3
  • 103
    • 34547754626 scopus 로고    scopus 로고
    • A Drosophila ortholog of the human cylindromatosis tumor suppressor gene regulates triglyceride content and antibacterial defense
    • Tsichritzis T., Gaentzsch P.C., Kosmidis S., Brown A.E., Skoulakis E.M., Ligoxygakis P., et al. A Drosophila ortholog of the human cylindromatosis tumor suppressor gene regulates triglyceride content and antibacterial defense. Development (Cambridge, England) 2007, 134(14):2605-2614. 10.1242/dev.02859.
    • (2007) Development (Cambridge, England) , vol.134 , Issue.14 , pp. 2605-2614
    • Tsichritzis, T.1    Gaentzsch, P.C.2    Kosmidis, S.3    Brown, A.E.4    Skoulakis, E.M.5    Ligoxygakis, P.6
  • 104
    • 0035423794 scopus 로고    scopus 로고
    • Mutations in the Drosophila dTAK1 gene reveal a conserved function for MAPKKKs in the control of rel/NF-kappaB-dependent innate immune responses
    • Vidal S., Khush R.S., Leulier F., Tzou P., Nakamura M., Lemaitre B. Mutations in the Drosophila dTAK1 gene reveal a conserved function for MAPKKKs in the control of rel/NF-kappaB-dependent innate immune responses. Genes & Development 2001, 15(15):1900-1912. 10.1101/gad.203301.
    • (2001) Genes & Development , vol.15 , Issue.15 , pp. 1900-1912
    • Vidal, S.1    Khush, R.S.2    Leulier, F.3    Tzou, P.4    Nakamura, M.5    Lemaitre, B.6
  • 106
    • 48749109290 scopus 로고    scopus 로고
    • Pyogenic bacterial infections in humans with MyD88 deficiency
    • Von Bernuth H., Picard C., Jin Z., Pankla R., Xiao H., Ku C.-L., et al. Pyogenic bacterial infections in humans with MyD88 deficiency. Science (New York, N.Y.) 2008, 321(5889):691-696. 10.1126/science.1158298.
    • (2008) Science (New York, N.Y.) , vol.321 , Issue.5889 , pp. 691-696
    • Von Bernuth, H.1    Picard, C.2    Jin, Z.3    Pankla, R.4    Xiao, H.5    Ku, C.-L.6
  • 108
    • 33750218690 scopus 로고    scopus 로고
    • Sensing of Gram-positive bacteria in Drosophila: GNBP1 is needed to process and present peptidoglycan to PGRP-SA
    • Wang L., Weber A.N.R., Atilano M.L., Filipe S.R., Gay N.J., Ligoxygakis P. Sensing of Gram-positive bacteria in Drosophila: GNBP1 is needed to process and present peptidoglycan to PGRP-SA. The EMBO Journal 2006, 25(20):5005-5014. 10.1038/sj.emboj.7601363.
    • (2006) The EMBO Journal , vol.25 , Issue.20 , pp. 5005-5014
    • Wang, L.1    Weber, A.N.R.2    Atilano, M.L.3    Filipe, S.R.4    Gay, N.J.5    Ligoxygakis, P.6
  • 109
    • 77649265237 scopus 로고    scopus 로고
    • Pathogen entrapment by transglutaminase-A conserved early innate immune mechanism
    • Wang Z., Wilhelmsson C., Hyrsl P., Loof T.G., Dobes P., Klupp M., et al. Pathogen entrapment by transglutaminase-A conserved early innate immune mechanism. PLoS Pathogens 2010, 6(2):e1000763. 10.1371/journal.ppat.1000763.
    • (2010) PLoS Pathogens , vol.6 , Issue.2
    • Wang, Z.1    Wilhelmsson, C.2    Hyrsl, P.3    Loof, T.G.4    Dobes, P.5    Klupp, M.6
  • 111


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.