Elimination of plasmatocytes by targeted apoptosis reveals their role in multiple aspects of the Drosophila immune response

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 24, 2009, Pages 9797-9802

  Charroux, Bernard ^a   Royet, Julien ^a  

^a AIX MARSEILLE UNIVERSITÉ   (France)

Author keywords

AMP; Blood cells; Innate immunity; Toll

Indexed keywords

POLYPEPTIDE ANTIBIOTIC AGENT;

APOPTOSIS; ARTICLE; BACTERIAL INFECTION; BODY FAT; CELL FUNCTION; CELL PROLIFERATION; DROSOPHILA; GENETIC SUSCEPTIBILITY; GENETIC TRANSCRIPTION; IMMUNE DEFICIENCY; IMMUNE RESPONSE; LARVAL STAGE; NONHUMAN; PHAGOCYTOSIS; PLASMA CELL; PRIORITY JOURNAL; PUPA (LIFE CYCLE STAGE); WILD TYPE;

ADENOSINE MONOPHOSPHATE; ANIMALS; APOPTOSIS; DROSOPHILA MELANOGASTER; HEMOCYTES; IMMUNITY, INNATE; IN SITU NICK-END LABELING;

ANIMALIA; BACTERIA (MICROORGANISMS);

EID: 67649878194     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0903971106     Document Type: Article

References (34)

1. Evans CJ, Banerjee U (2003) Transcriptional regulation of hematopoiesis in Drosophila. Blood Cells Mol Dis 30:223-228.
2. Evans CJ, Hartenstein V, Banerjee U (2003) Thicker than blood: Conserved mechanisms in Drosophila and vertebrate hematopoiesis. Dev Cell 5:673-690. (Pubitemid 37362212)
3. Crozatier M, Meister M (2007) Drosophila haematopoiesis. Cell Microbiol 9:1117-1126.
4. Tepass U, Fessler LI, Aziz A, Hartenstein V (1994) Embryonic origin of hemocytes and their relationship to cell death in Drosophila. Development 120:1829-1837. (Pubitemid 24209717)
5. Lebestky T, Chang T, Hartenstein V, Banerjee U (2000) Specification of Drosophila hematopoietic lineage by conserved transcription factors. Science 288:146-149. (Pubitemid 30203049)
6. Lanot R, Zachary D, Holder F, Meister M (2001) Postembryonic hematopoiesis in Drosophila. Dev Biol 230:243-257.
7. Franc NC, Dimarcq JL, Lagueux M, Hoffmann J, Ezekowitz RA (1996) Croquemort, a novel Drosophila hemocyte/macrophage receptor that recognizes apoptotic cells. Immunity 4:431-443. (Pubitemid 26354653)
8. Franc NC, Heitzler P, Ezekowitz RA, White K (1999) Requirement for croquemort in phagocytosis of apoptotic cells in Drosophila. Science 284:1991-1994. (Pubitemid 29309447)
9. Kocks C, et al. (2005) Eater, a transmembrane protein mediating phagocytosis of bacterial pathogens in Drosophila. Cell 123:335-346. (Pubitemid 41457221)
10. Ramet M, et al. (2001) Drosophila scavenger receptor CI is a pattern recognition receptor for bacteria. Immunity 15:1027-1038. (Pubitemid 34075381)
11. Dimarcq JL, et al. (1997) Treatment of l(2)mbn Drosophila tumorous blood cells with the steroid hormone ecdysone amplifies the inducibility of antimicrobial peptide gene expression. Insect Biochem Mol Biol 27:877-886. (Pubitemid 28076517)
12. Krzemien J, et al. (2007) Control of blood cell homeostasis in Drosophila larvae by the posterior signalling centre. Nature 446:325-328. (Pubitemid 46426162)
13. Crozatier M, Ubeda JM, Vincent A, Meister M (2004) Cellular immune response to parasitization in Drosophila requires the EBF orthologue collier. PLoS Biol 2:E196. (Pubitemid 39245266)
14. Mandal L, Martinez-Agosto JA, Evans CJ, Hartenstein V, Banerjee U (2007) A Hedgehog- and Antennapedia-dependent niche maintains Drosophila haematopoietic precursors. Nature 446:320-324. (Pubitemid 46426149)
15. Elrod-Erickson M, Mishra S, Schneider D (2000) Interactions between the cellular and humoral immune responses in Drosophila. Curr Biol 10:781-784. (Pubitemid 30466941)
16. Rizki TM, Rizki RM (1992) Lamellocyte differentiation in Drosophila larvae parasitized by Leptopilina. Dev Comp Immunol 16:103-110.
17. Basset A, et al. (2000) The phytopathogenic bacteria Erwinia carotovora infects Drosophila and activates an immune response. Proc Natl Acad Sci USA 97:3376-3381. (Pubitemid 30183310)
18. Ruhf ML, et al. (2001) The domino gene of Drosophila encodes novel members of the SWI2/SNF2 family of DNA-dependent ATPases, which contribute to the silencing of homeotic genes. Development 128:1429-1441. (Pubitemid 32409662)
19. Braun A, Hoffmann JA, Meister M (1998) Analysis of the Drosophila host defense in domino mutant larvae, which are devoid of hemocytes. Proc Natl Acad Sci USA 95:14337-14342. (Pubitemid 28549368)
20. Goto A, Kadowaki T, Kitagawa Y (2003) Drosophila hemolectin gene is expressed in embryonic and larval hemocytes and its knock down causes bleeding defects. Dev Biol 264:582-591. (Pubitemid 37490987)
21. Sinenko SA, Mathey-Prevot B (2004) Increased expression of Drosophila tetraspanin, Tsp68C, suppresses the abnormal proliferation of ytr-deficient and Ras/Raf-activated hemocytes. Oncogene 23:9120-9128. (Pubitemid 40013079)
22. Jung SH, Evans CJ, Uemura C, Banerjee U (2005) The Drosophila lymph gland as a developmental model of hematopoiesis. Development 132:2521-2533. (Pubitemid 40883253)
23. Braun A, Lemaitre B, Lanot R, Zachary D, MeisterM(1997) Drosophila immunity: Analysis of larval hemocytes by P-element-mediated enhancer trap. Genetics 147:623-634.
24. Foley E, O'Farrell PH (2003) Nitric oxide contributes to induction of innate immune responses to gram-negative bacteria in Drosophila. Genes Dev 17:115-125. (Pubitemid 36062513)
25. Brennan CA, Delaney JR, Schneider DS, Anderson KV (2007) Psidin is required in Drosophila blood cells for both phagocytic degradation and immune activation of the fat body. Curr Biol 17:67-72. (Pubitemid 46027571)
26. Ligoxygakis P, Bulet P, Reichhart JM (2002) Critical evaluation of the role of the Toll-like receptor 18-Wheeler in the host defense of Drosophila. EMBO Rep 3:666-673. (Pubitemid 34884992)
27. Kurucz E, et al. (2007) Nimrod, a putative phagocytosis receptor with EGF repeats in Drosophila plasmatocytes. Curr Biol 17:649-654. (Pubitemid 46509583)
28. Irving P, et al. (2005) New insights into Drosophila larval haemocyte functions through genome-wide analysis. Cell Microbiol 7:335-350. (Pubitemid 40277914)
29. Levashina EA, et al. (1999) Constitutive activation of toll-mediated antifungal defense in serpin-deficient Drosophila. Science 285:1917-1919. (Pubitemid 129515514)
30. Gottar M, et al. (2002) The Drosophila immune response against Gram-negative bacteria is mediated by a peptidoglycan recognition protein. Nature 416:640-644. (Pubitemid 34406765)
31. Ramet M, Manfruelli P, Pearson A, Mathey-Prevot B, Ezekowitz RA (2002) Functional genomic analysis of phagocytosis and identification of a Drosophila receptor for E. coli. Nature 416:644-648. (Pubitemid 34406766)
32. Choe KM, Lee H, Anderson KV (2005) Drosophila peptidoglycan recognition protein LC (PGRP-LC) acts as a signal-transducing innate immune receptor. Proc Natl Acad Sci USA 102:1122-1126. (Pubitemid 40170736)
33. Maillet F, Bischoff V, Vignal C, Hoffmann J, Royet J (2008) The Drosophila peptidoglycan recognition protein PGRP-LF blocks PGRP-LC and IMD/JNK pathway activation. Cell Host Microbe 3:293-303. (Pubitemid 351637430)
34. Reichhart JM, et al. (1992). Insect immunity: Developmental and inducible activity of the Drosophila diptericin promoter. EMBO J 11:1469-1477.