Gene regulatory networks controlling hematopoietic progenitor niche cell production and differentiation in the Drosophila lymph gland

PLoS ONE

Volumn 7, Issue 7, 2012, Pages

  Tokusumi, Yumiko ^a   Tokusumi, Tsuyoshi ^a   Shoue, Douglas A ^a   Schulz, Robert A ^a  

^a UNIVERSITY OF NOTRE DAME   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SOMATOMEDIN; TARGET OF RAPAMYCIN KINASE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BLOOD CELL; CELL DIFFERENTIATION; CELL MATURATION; CHROMATIN ASSEMBLY AND DISASSEMBLY; CONTROLLED STUDY; GAIN OF FUNCTION MUTATION; GENE FUNCTION; GENE INTERACTION; GENE LOCUS; GENE REGULATORY NETWORK; HEDGEHOG GENE; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; HOMEOSTASIS; INNATE IMMUNITY; LAMELLOCYTE; LOSS OF FUNCTION MUTATION; LYMPH NODE; NONHUMAN; PHENOTYPE; POSTERIOR SIGNALING CENTER; PTEN GENE; REGULATORY MECHANISM; RNA INTERFERENCE; SIGNAL TRANSDUCTION; STEM CELL NICHE; TSC1 GENE; TSC2 GENE; TUMOR SUPPRESSOR GENE;

ANIMALS; BIOLOGICAL MARKERS; BLOOD CELLS; CELL COUNT; CELL DIFFERENTIATION; CHROMATIN ASSEMBLY AND DISASSEMBLY; DIET; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; FEEDING BEHAVIOR; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE KNOCKDOWN TECHNIQUES; GENE REGULATORY NETWORKS; GENES, INSECT; HEMATOPOIETIC STEM CELLS; HEMOLYMPH; HOMEOSTASIS; LARVA; LYMPH NODES; MUTATION; ORGAN SIZE; ORGAN SPECIFICITY; RNA INTERFERENCE; SIGNAL TRANSDUCTION; STEM CELL NICHE;

ERINACEIDAE;

EID: 84864248668     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0041604     Document Type: Article

References (42)

1. Lin H, (2002) The stem-cell niche theory: lessons from flies. Nat Rev 3: 931-940.
2. Martinez-Agosto JA, Mikkola HKA, Hartenstein V, Banerjee U, (2007) The hematopoietic stem cell and its niche: a comparative view. Genes Dev 21: 3044-3060.
3. Morrison SJ, Spradling AC, (2008) Stem cells and niches: mechanisms that promote stem cell maintenance throughout life. Cell 132: 598-611.
4. Kohlmaier A, Edgar BA, (2008) Proliferative control in Drosophila stem cells. Curr Opin Cell Bio 20: 699-706.
5. Orkin SH, Zon LI, (2008) Hematopoiesis: an evolving paradigm for stem cell biology. Cell 132: 631-644.
6. Krzemien J, Dubois L, Makki R, Meister M, Vincent A, et al. (2007) Control of blood cell homeostasis in Drosophila larvae by the posterior signaling centre. Nature 446: 325-328.
7. Mandal L, Martinez-Agosto JA, Evans CJ, Hartenstein V, Banerjee U, (2007) A Hedgehog- and Antennapedia-dependent niche maintains Drosophila haematopoietic precursors. Nature 446: 320-324.
8. Tokusumi Y, Tokusumi T, Stoller-Conrad J, Schulz RA, (2010) Serpent, Suppressor of Hairless and U-shaped are crucial regulators of hedgehog niche expression and prohemocyte maintenance during Drosophila larval hematopoiesis. Development 137: 3561-3568.
9. Gao H, Wu X, Fossett N, (2009) Up-regulation of the Drosophila Friend of GATA gene u-shaped by JAK/STAT signaling maintains lymph gland prohemocyte potency. Mol Cell Biol 29: 6086-6096.
10. Tokusumi T, Tokusumi Y, Hopkins DW, Shoue DA, Corona L, et al. (2011) Germ line differentiation factor Bag of Marbles is a regulator of hematopoietic progenitor maintenance during Drosophila hematopoiesis. Development 138: 3879-3884.
11. Minakhina S, Steward R, (2010) Hematopoietic stem cells in Drosophila. Development 137: 27-31.
12. Krzemien J, Oyallon J, Crozatier M, Vincent A, (2010) Hematopoietic progenitors and hemocyte lineages in the Drosophila lymph gland. Dev Biol 346: 310-319.
13. Zettervall CJ, Anderl I, Williams MJ, Palmer R, Kurucz E, et al. (2004) A directed screen for genes involved in Drosophila blood cell activation. Proc Natl Acad Sci USA 101: 14192-14197.
14. Lanot R, Zachary D, Holder F, Meister M, (2001) Postembryonic hematopoiesis in Drosophila. Dev Biol 230: 243-257.
15. Jung SH, Evans CJ, Uemura C, Banerjee U, (2005) The Drosophila lymph gland as a developmental model of hematopoiesis. Development 132: 2521-2533.
16. Crozatier M, Ubeda JM, Vincent A, Meister M, (2004) Cellular immune response to parasitization in Drosophila requires the EBF orthologue Collier. PLoS Biol 2: e196.
17. Sinenko SA, Mandal L, Martinez-Agostso JA, Banerjee U, (2009) Dual role of Wingless signaling in stem-like hematopoietic precursor maintenance in Drosophila. Dev Cell 16: 756-763.
18. Pennetier D, Oyallon J, Morin-Poulard I, Dejean S, Vincent A, et al. (2012) Size control of the Drosophila hematopoietic niche by bone morphogenetic protein signaling reveals parallels with mammals. Proc Natl Acad Sci USA 109: 3389-3394.
19. Benmimoun B, Polesello C, Waltzer L, Haenlin M, (2012) Dual role for Insulin/TOR signaling in the control of hematopoietic progenitor maintenance in Drosophila. Development 139: 1713-1717.
20. Lebestky T, Jung SH, Banerjee U, (2003) A Serrate-expressing signaling center controls Drosophila hematopoiesis. Genes Dev 17: 348-353.
21. Mondal BC, Mukherjee T, Mandal L, Evans CJ, Sinenko SA, et al. (2011) Interaction between differentiating cell- and niche-derived signals in hematopoietic progenitor maintenance. Cell 147: 1589-1600.
22. Sinenko SA, Shim J, Banerjee U, (2011) Oxidative stress in the haematopoietic niche regulates the cellular immune response in Drosophila. EMBO Rep 13: 83-89.
23. Crozatier M, Vincent A, (2011) Drosophila: a model for studying genetic and molecular aspects of haematopoiesis and associated leukaemias. DMM 4: 439-445.
24. Yoo AS, Crabtree GR, (2009) ATP-dependent chromatin remodeling in neural development. Curr Opin Neurobiol 19: 120-126.
25. Terriente-Felix A, de Celis JF, (2009) Osa, a subunit of the BAP chromatin-remodeling complex, participates in the regulation of gene expression in response to EGFR signaling in the Drosophila wing. Dev Biol 329: 350-361.
26. Edgar BA, (2006) How flies get their size: genetics meets physiology. Nature Rev Genet 7: 907-916.
27. Yilmaz OH, Valdez R, Theisen BK, Guo W, Ferguson DO, et al. (2006) Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells. Nature 441: 475-482.
28. Zhang J, Grindley JC, Yin T, Jayasinghe S, He XC, et al. (2006) PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia protection. Nature 441: 518-522.
29. Kim D-H, Sarbassov DD, Ali SM, King JE, Latek RR, et al. (2002) mTOR interacts with Raptor to form a nutrient-sensitive complex that signals to the cell growth machinery. Cell 110: 163-175.
30. Sarbassov DD, Ali SM, Kim D-H, Guertin DA, Latek RR, et al. (2004) Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton. Curr Biol 14: 1296-1302.
31. Chen C, Liu Y, Liu R, Ikenoue T, Guan K-L, et al. (2008) TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species. J Exp Med 205: 2397-2408.
32. Gan B, DePinho RA, (2009) mTORC1 signaling governs hematopoietic stem cell quiescence. Cell Cycle 8: 1003-1006.
33. Shim J, Mukherjee T, Banerjee U, (2012) Direct sensing of systemic and nutritional signals by haematopoietic progenitors in Drosophila. Nat Cell Biol 14: 394-400.
34. Napolioni V, Curatolo P, (2008) Genetics and molecular biology of Tuberous Sclerosis Complex. Curr Genom 9: 475-487.
35. Tokusumi T, Shoue DA, Tokusumi Y, Stoller JR, Schulz RA, (2009) New hemocyte-specific enhancer-reporter transgenes for the analysis of hematopoiesis in Drosophila. Genesis 47: 771-774.
36. Junger MA, Rintelen F, Stocker H, Wasserman JD, Vegh M, et al. (2003) The Drosophila forkhead transcription factor FOXO mediates the reduction in cell number associated with reduced insulin signaling. J Biol 2: 20.
37. Oldham S, Stocker H, Laffargue M, Wittwer F, Wymann M, et al. (2002) The Drosophila insulin/IGF receptor controls growth and size by modulating PtdInsP(3) levels. Development 129: 4103-4109.
38. Montagne J, Stewart MJ, Stocker H, Hafen E, Kozma SC, et al. (1999) Drosophila S6 kinase: a regulator of cell size. Science 285: 2126-2129.
39. Hombria JC, Brown S, Hader S, Zeidler MP, (2005) Characterisation of Upd2, a Drosophila JAK/STAT pathway ligand. Dev Biol 288: 420-433.
40. Vilmos P, Nagy I, Kurucz E, Hultmark D, Gateff E, et al. (2004) A rapid rosetting method for separation of hemocyte sub-populations of Drosophila melanogaster. Dev Comp Immunol 28: 555-563.
41. Sorrentino RP, Tokusumi T, Schulz RA, (2007) The Friend of GATA protein U-shaped functions as a hematopoietic tumor suppressor in Drosophila. Dev Biol 311: 311-323.
42. Tokusumi T, Sorrentino RP, Russell M, Ferrarese R, Govind S, et al. (2009) Characterization of a lamellocyte transcriptional enhancer located within the misshapen gene of Drosophila melanogaster. PloS One 4: e6429.