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Volumn 180, Issue 8, 2008, Pages 5413-5422

Pirk is a negative regulator of the Drosophila Imd pathway

Author keywords

[No Author keywords available]

Indexed keywords

CYTOPLASM PROTEIN; PEPTIDOGLYCAN RECOGNITION PROTEIN; CARRIER PROTEIN; DROSOPHILA PROTEIN; IMMUNE DEFICIENCY PROTEIN, DROSOPHILA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PIRK PROTEIN, DROSOPHILA;

EID: 43049171620     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.180.8.5413     Document Type: Article
Times cited : (175)

References (48)
  • 1
    • 33750435582 scopus 로고    scopus 로고
    • NF-κB and the immune response
    • Hayden, M. S., A. P. West, and S. Ghosh. 2006. NF-κB and the immune response. Oncogene 25: 6758-6780.
    • (2006) Oncogene , vol.25 , pp. 6758-6780
    • Hayden, M.S.1    West, A.P.2    Ghosh, S.3
  • 2
    • 33845768987 scopus 로고    scopus 로고
    • Integrating cell-signalling pathways with NF-κB and IKK function
    • Perkins, N. D. 2007. Integrating cell-signalling pathways with NF-κB and IKK function. Nat. Rev. Mol. Cell Biol. 8: 49-62.
    • (2007) Nat. Rev. Mol. Cell Biol , vol.8 , pp. 49-62
    • Perkins, N.D.1
  • 3
    • 0037290892 scopus 로고    scopus 로고
    • Drosophila immunity: Paths and patterns
    • Hultmark, D. 2003. Drosophila immunity: paths and patterns. Curr. Opin. Immunol. 15: 12-19.
    • (2003) Curr. Opin. Immunol , vol.15 , pp. 12-19
    • Hultmark, D.1
  • 4
    • 34047268684 scopus 로고    scopus 로고
    • The host defense of Drosophila melanogaster
    • Lemaitre, B., and J. Hoffmann. 2007. The host defense of Drosophila melanogaster. Annu. Rev. Immunol. 25: 697-743.
    • (2007) Annu. Rev. Immunol , vol.25 , pp. 697-743
    • Lemaitre, B.1    Hoffmann, J.2
  • 5
    • 35549006674 scopus 로고    scopus 로고
    • The Drosophila systemic immune response: Sensing and signalling during bacterial and fungal infections
    • Ferrandon, D., J.-L. Imler, C. Hetru, and J. A. Hoffmann. 2007. The Drosophila systemic immune response: sensing and signalling during bacterial and fungal infections. Nat. Rev. Immunol. 7: 862-874.
    • (2007) Nat. Rev. Immunol , vol.7 , pp. 862-874
    • Ferrandon, D.1    Imler, J.-L.2    Hetru, C.3    Hoffmann, J.A.4
  • 6
    • 0037061482 scopus 로고    scopus 로고
    • Functional genomic analysis of phagocytosis and identification of a Drosophila receptor for E. coli
    • Ramet, M., P. Manfruelli, A. Pearson, B. Mathey-Prevot, and R. A. Ezekowitz. 2002. Functional genomic analysis of phagocytosis and identification of a Drosophila receptor for E. coli. Nature 416: 644-648.
    • (2002) Nature , vol.416 , pp. 644-648
    • Ramet, M.1    Manfruelli, P.2    Pearson, A.3    Mathey-Prevot, B.4    Ezekowitz, R.A.5
  • 7
    • 0037066464 scopus 로고    scopus 로고
    • Requirement for a peptidoglycan recognition protein (PGRP) in Relish activation and antibacterial immune responses in Drosophila
    • Choe, K. M., T. Werner, S. Stöven, D. Hultmark, and K. V. Anderson. 2002. Requirement for a peptidoglycan recognition protein (PGRP) in Relish activation and antibacterial immune responses in Drosophila. Science 296: 359-362.
    • (2002) Science , vol.296 , pp. 359-362
    • Choe, K.M.1    Werner, T.2    Stöven, S.3    Hultmark, D.4    Anderson, K.V.5
  • 8
    • 0037061450 scopus 로고    scopus 로고
    • The Drosophila immune response against Gram-negative bacteria is mediated by peptidoglycan recognition protein
    • Gottar, M., V. Gobert, T. Michel, M. Belvin, G. Duyk, J. A. Hoffmann, D. Ferrandon, and J. Royet. 2002. The Drosophila immune response against Gram-negative bacteria is mediated by peptidoglycan recognition protein. Nature 416: 640-644.
    • (2002) Nature , vol.416 , pp. 640-644
    • Gottar, M.1    Gobert, V.2    Michel, T.3    Belvin, M.4    Duyk, G.5    Hoffmann, J.A.6    Ferrandon, D.7    Royet, J.8
  • 10
    • 12844279852 scopus 로고    scopus 로고
    • Drosophila peptidoglycan recognition protein LC (PGRP-LC) acts as a signal-transducing innate immune receptor
    • Choe, K. M., H. Lee, and K. V. Anderson. 2005. Drosophila peptidoglycan recognition protein LC (PGRP-LC) acts as a signal-transducing innate immune receptor. Proc. Natl. Acad. Sci. USA 102: 1122-1126.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 1122-1126
    • Choe, K.M.1    Lee, H.2    Anderson, K.V.3
  • 11
    • 0037172656 scopus 로고    scopus 로고
    • Inducible expression of double-stranded RNA reveals a role for dFADD in the regulation of the antibacterial response in Drosophila adults
    • Leulier, F., S. Vidal, K. Saigo, R. Ueda, and B. Lemaitre. 2002. Inducible expression of double-stranded RNA reveals a role for dFADD in the regulation of the antibacterial response in Drosophila adults. Curr. Biol. 12: 996-1000.
    • (2002) Curr. Biol , vol.12 , pp. 996-1000
    • Leulier, F.1    Vidal, S.2    Saigo, K.3    Ueda, R.4    Lemaitre, B.5
  • 12
    • 85036807126 scopus 로고    scopus 로고
    • Silverman, N, R. Zhou, S. Stöven, N. Pandey, D. Hultmark, and T Maniatis
    • Silverman, N., R. Zhou, S. Stöven, N. Pandey, D. Hultmark, and T Maniatis.
  • 13
    • 0034287444 scopus 로고    scopus 로고
    • A Drosophila IκB kinase complex required for Relish cleavage and antibacterial immunity. Genes Dev. 14: 2461-2471.
    • A Drosophila IκB kinase complex required for Relish cleavage and antibacterial immunity. Genes Dev. 14: 2461-2471.
  • 14
    • 0034305744 scopus 로고    scopus 로고
    • Leulier, F., A. Rodriguez, R. S. Khush, J. M. Abrams, and B. Lemaitre. 2000. The Drosophila caspase Dredd is required to resist Gram-negative bacterial infection. EMBO Rep. 1: 353-358.
    • Leulier, F., A. Rodriguez, R. S. Khush, J. M. Abrams, and B. Lemaitre. 2000. The Drosophila caspase Dredd is required to resist Gram-negative bacterial infection. EMBO Rep. 1: 353-358.
  • 15
    • 0034303480 scopus 로고    scopus 로고
    • Stöven, S., I. Ando, L. Kadalayil, Y. Engström, and D. Hultmark. 2000. Activation of the Drosophila NF-κB factor Relish by rapid endoproteolytic cleavage. EMBO Rep. 1: 347-352.
    • Stöven, S., I. Ando, L. Kadalayil, Y. Engström, and D. Hultmark. 2000. Activation of the Drosophila NF-κB factor Relish by rapid endoproteolytic cleavage. EMBO Rep. 1: 347-352.
  • 17
    • 85036818418 scopus 로고    scopus 로고
    • Vidal, S, R. S. Khush, F. Leulier, P. Tzou, M. Nakamura, and B. Lemaitre
    • Vidal, S., R. S. Khush, F. Leulier, P. Tzou, M. Nakamura, and B. Lemaitre.
  • 18
    • 0035423794 scopus 로고
    • Mutations in the Drosophila dTAK1 gene reveal a conserved function for MAPKKKs in the control of rel/NF-κB-dependent innate immune responses
    • Mutations in the Drosophila dTAK1 gene reveal a conserved function for MAPKKKs in the control of rel/NF-κB-dependent innate immune responses. Genes Dev. 15: 1900-1912.
    • (1900) Genes Dev , vol.15
  • 20
    • 27344453240 scopus 로고    scopus 로고
    • Gesellchen, V., D. Kuttenkeuler, M. Steckel, N. Pelte, and M. Boutros. 2005. An RNA interference screen identifies inhibitor of apoptosis protein 2 as a regulator of innate immune signaling in Drosophila. EMBO Rep. 6: 979-984.
    • Gesellchen, V., D. Kuttenkeuler, M. Steckel, N. Pelte, and M. Boutros. 2005. An RNA interference screen identifies inhibitor of apoptosis protein 2 as a regulator of innate immune signaling in Drosophila. EMBO Rep. 6: 979-984.
  • 21
    • 33750330952 scopus 로고    scopus 로고
    • The Drosophila inhibitor of apoptosis protein DIAP2 functions in innate immunity and is essential to resist Gram-negative bacterial infection
    • Leulier, F., N. Lhocine, B. Lemaitre, and P. Meier. 2006. The Drosophila inhibitor of apoptosis protein DIAP2 functions in innate immunity and is essential to resist Gram-negative bacterial infection. Mol. Cell. Biol. 26: 7821-7831.
    • (2006) Mol. Cell. Biol , vol.26 , pp. 7821-7831
    • Leulier, F.1    Lhocine, N.2    Lemaitre, B.3    Meier, P.4
  • 22
  • 23
    • 19344370696 scopus 로고    scopus 로고
    • Functional dissection of an innate immune response by a genome-wide RNAi screen
    • Foley, E., and P. H. O'Farrell. 2004. Functional dissection of an innate immune response by a genome-wide RNAi screen. PLoS Biol. 2: e203.
    • (2004) PLoS Biol , vol.2
    • Foley, E.1    O'Farrell, P.H.2
  • 24
    • 0036848010 scopus 로고    scopus 로고
    • Sequential activation of signaling pathways during innate immune responses in Drosophila
    • Boutros, M., H. Agaisse, and N. Perrimon. 2002. Sequential activation of signaling pathways during innate immune responses in Drosophila. Dev. Cell 3: 711-722.
    • (2002) Dev. Cell , vol.3 , pp. 711-722
    • Boutros, M.1    Agaisse, H.2    Perrimon, N.3
  • 26
    • 33645770760 scopus 로고    scopus 로고
    • Downregulation of the Drosophila immune response by peptidoglycanrecognition proteins SC1 and SC2
    • Bischoff, V., C. Vignal, B. Duvic, I. G. Boneca, J. A. Hoffmann, and J. Royet. 2006. Downregulation of the Drosophila immune response by peptidoglycanrecognition proteins SC1 and SC2. PLoS Pathog. 2: e14.
    • (2006) PLoS Pathog , vol.2
    • Bischoff, V.1    Vignal, C.2    Duvic, B.3    Boneca, I.G.4    Hoffmann, J.A.5    Royet, J.6
  • 27
    • 35449002517 scopus 로고    scopus 로고
    • Peptidoglycan recognition protein LF: A negative regulator of Drosophila immunity
    • Persson, C, S. Oldenvi, and H. Steiner. 2007. Peptidoglycan recognition protein LF: a negative regulator of Drosophila immunity. Insect Biochem. Mol. Biol. 37: 1309-1316.
    • (2007) Insect Biochem. Mol. Biol , vol.37 , pp. 1309-1316
    • Persson, C.1    Oldenvi, S.2    Steiner, H.3
  • 28
    • 0037108474 scopus 로고    scopus 로고
    • A ubiquitinproteasome pathway represses the Drosophila immune deficiency signalling cascade
    • Khush, R. S., W. D. Cornwell, J. N. Uram, and B. Lemaitre. 2002. A ubiquitinproteasome pathway represses the Drosophila immune deficiency signalling cascade. Curr. Biol. 12: 1728-1737.
    • (2002) Curr. Biol , vol.12 , pp. 1728-1737
    • Khush, R.S.1    Cornwell, W.D.2    Uram, J.N.3    Lemaitre, B.4
  • 29
    • 33750842525 scopus 로고    scopus 로고
    • Caspar, a suppressor of antibacterial immunity in Drosophila
    • Kim, M., J. H. Lee, S. Y. Lee, E. Kim, and J. Chung. 2006. Caspar, a suppressor of antibacterial immunity in Drosophila. Proc. Natl. Acad. Sci. USA 103: 16358-16363.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 16358-16363
    • Kim, M.1    Lee, J.H.2    Lee, S.Y.3    Kim, E.4    Chung, J.5
  • 30
    • 43049166899 scopus 로고    scopus 로고
    • Down-regulation of NF-κB target genes by the AP-1 and STAT complex during the innate immune response in Drosophila
    • Kim, L. K., U. Y. Choi, H. S. Cho, J. S. Lee, W. B. Lee, J. Kim, K. Jeong, J. Shim, J. Kim-Ha, and Y. J. Kim. 2007. Down-regulation of NF-κB target genes by the AP-1 and STAT complex during the innate immune response in Drosophila. PLoS Biol. 5: e238.
    • (2007) PLoS Biol , vol.5
    • Kim, L.K.1    Choi, U.Y.2    Cho, H.S.3    Lee, J.S.4    Lee, W.B.5    Kim, J.6    Jeong, K.7    Shim, J.8    Kim-Ha, J.9    Kim, Y.J.10
  • 31
    • 20444506693 scopus 로고    scopus 로고
    • Functional analysis of immune response genes in Drosophila identifies JNK pathway as a regulator of antimicrobial peptide gene expression in S2 cells
    • Kallio, J., A. Leinonen, J. Ulvila, S. Valanne, R. A. Ezekowitz, and M. Rämet. 2005. Functional analysis of immune response genes in Drosophila identifies JNK pathway as a regulator of antimicrobial peptide gene expression in S2 cells. Microbes Infect. 7: 811-819.
    • (2005) Microbes Infect , vol.7 , pp. 811-819
    • Kallio, J.1    Leinonen, A.2    Ulvila, J.3    Valanne, S.4    Ezekowitz, R.A.5    Rämet, M.6
  • 32
    • 0027160708 scopus 로고
    • Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
    • Brand, A. H., and N. Perrimon. 1993. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118: 401-415.
    • (1993) Development , vol.118 , pp. 401-415
    • Brand, A.H.1    Perrimon, N.2
  • 33
    • 0029031668 scopus 로고
    • Activation of a Drosophila Janus kinase (JAK) causes hematopoietic neoplasia and developmental defects
    • Harrison, D. A., R. Binari, T. S. Nahreini, M. Gilman, and N. Perrimon. 1995. Activation of a Drosophila Janus kinase (JAK) causes hematopoietic neoplasia and developmental defects. EMBO J. 14: 2857-2865.
    • (1995) EMBO J , vol.14 , pp. 2857-2865
    • Harrison, D.A.1    Binari, R.2    Nahreini, T.S.3    Gilman, M.4    Perrimon, N.5
  • 37
    • 47149117454 scopus 로고    scopus 로고
    • Evolution of genes and genomes on the Drosophila phylogeny
    • Drosophila 12 Genomes Consortium
    • Drosophila 12 Genomes Consortium. 2007. Evolution of genes and genomes on the Drosophila phylogeny. Nature 450: 203-218.
    • (2007) Nature , vol.450 , pp. 203-218
  • 41
    • 10344265019 scopus 로고    scopus 로고
    • A draft sequence for the genome of the domesticated silkworm (Bombyx mori)
    • Xia, Q., Z. Zhou, C. Lu, D. Cheng, F. Dai, B. Li, P. Zhao, X. Zha, T. Cheng, C. Chai, et al. 2004. A draft sequence for the genome of the domesticated silkworm (Bombyx mori). Science 306: 1937-1940.
    • (2004) Science , vol.306 , pp. 1937-1940
    • Xia, Q.1    Zhou, Z.2    Lu, C.3    Cheng, D.4    Dai, F.5    Li, B.6    Zhao, P.7    Zha, X.8    Cheng, T.9    Chai, C.10
  • 42
    • 33750460281 scopus 로고    scopus 로고
    • Insights into social insects from the genome of the honeybee Apis mellifera
    • The Honeybee Genome Sequencing Consortium
    • The Honeybee Genome Sequencing Consortium. 2006. Insights into social insects from the genome of the honeybee Apis mellifera. Nature 443: 931-949.
    • (2006) Nature , vol.443 , pp. 931-949
  • 44
    • 0026486817 scopus 로고
    • Cactus, a gene involved in dorsoventral pattern formation of Drosophila, is related to the IκB gene family of vertebrates
    • Geisler, R., A. Bergmann, Y. Hiromi, and C. Nüsslein-Volhard. 1992. Cactus, a gene involved in dorsoventral pattern formation of Drosophila, is related to the IκB gene family of vertebrates. Cell 71: 613-621.
    • (1992) Cell , vol.71 , pp. 613-621
    • Geisler, R.1    Bergmann, A.2    Hiromi, Y.3    Nüsslein-Volhard, C.4
  • 47
    • 0038036294 scopus 로고    scopus 로고
    • Functional diversity of the Drosophila PGRP-LC gene cluster in the response to lipopolysaccharide and peptidoglycan
    • Werner, T., K. Borge-Renberg, P. Mellroth, H. Steiner, and D. Hultmark. 2003. Functional diversity of the Drosophila PGRP-LC gene cluster in the response to lipopolysaccharide and peptidoglycan. J. Biol. Chem. 278: 26319-26322.
    • (2003) J. Biol. Chem , vol.278 , pp. 26319-26322
    • Werner, T.1    Borge-Renberg, K.2    Mellroth, P.3    Steiner, H.4    Hultmark, D.5


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