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Volumn 15, Issue , 2013, Pages 1-28

Topology and dynamics of signaling networks: In search of transcriptional control of the inflammatory response

Author keywords

computational modeling; inflammation; phosphoproteins; proteomics; signal transduction

Indexed keywords

COMPUTATIONAL MODELING; COMPUTATIONAL TECHNIQUE; INFLAMMATION; INFLAMMATORY RESPONSE; PHOSPHOPROTEINS; PROTEOMICS; TRANSCRIPTIONAL ACTIVITY; TRANSCRIPTIONAL CONTROL;

EID: 84880550422     PISSN: 15239829     EISSN: 15454274     Source Type: Book Series    
DOI: 10.1146/annurev-bioeng-071812-152425     Document Type: Review
Times cited : (11)

References (107)
  • 1
    • 14044278401 scopus 로고    scopus 로고
    • Mechanisms of inflammation: The good, the bad and the ugly
    • Laroux FS. 2004. Mechanisms of inflammation: The good, the bad and the ugly. Front. Biosci. 9:3156-62
    • (2004) Front. Biosci , vol.9 , pp. 3156-3162
    • Laroux, F.S.1
  • 2
    • 0030587937 scopus 로고    scopus 로고
    • Immunologic dissonance: A continuing evolution in our understanding of the systemic inflammatory response syndrome (SIRS) and the multiple organ dysfunction syndrome (MODS)
    • Bone RC. 1996. Immunologic dissonance: A continuing evolution in our understanding of the systemic inflammatory response syndrome (SIRS) and the multiple organ dysfunction syndrome (MODS). Ann. Intern. Med. 125:680-87
    • (1996) Ann. Intern. Med , vol.125 , pp. 680-687
    • Bone, R.C.1
  • 3
    • 77957580213 scopus 로고    scopus 로고
    • Translational systems biology of inflammation: Potential applications to personalized medicine
    • Mi Q, Li N, ZiraldoC,Ghuma A, Mikheev M, et al. 2010. Translational systems biology of inflammation: Potential applications to personalized medicine. Personalized Med. 7:549-59
    • (2010) Personalized Med , vol.7 , pp. 549-559
    • Mi, Q.1    Li, N.2    Ziraldo, C.3    Ghuma, A.4    Mikheev, M.5
  • 4
    • 0037180812 scopus 로고    scopus 로고
    • Points of control in inflammation
    • Nathan C. 2002. Points of control in inflammation. Nature 420:846-52
    • (2002) Nature , vol.420 , pp. 846-852
    • Nathan, C.1
  • 5
    • 7644232415 scopus 로고    scopus 로고
    • Evolution of innate and adaptive immunity: Can we draw a line?
    • Flajnik MF, Du Pasquier L 2004. Evolution of innate and adaptive immunity: Can we draw a line? Trends Immunol. 25:640-44
    • (2004) Trends Immunol , vol.25 , pp. 640-644
    • Flajnik, M.F.1    Du Pasquier, L.2
  • 6
    • 21744440089 scopus 로고    scopus 로고
    • The acute inflammatory response in diverse shock states
    • Chow CC, Clermont G, Kumar R, Lagoa C, Tawadrous Z, et al. 2005. The acute inflammatory response in diverse shock states. Shock 24:74-84
    • (2005) Shock , vol.24 , pp. 74-84
    • Chow, C.C.1    Clermont, G.2    Kumar, R.3    Lagoa, C.4    Tawadrous, Z.5
  • 7
    • 67749139592 scopus 로고    scopus 로고
    • Mathematical modeling of posthemorrhage inflammation in mice: Studies using a novel, computer-controlled, closed-loop hemorrhage apparatus
    • TorresA,Bentley T, Bartels J, Sarkar J,Barclay D, et al. 2009. Mathematical modeling of posthemorrhage inflammation in mice: Studies using a novel, computer-controlled, closed-loop hemorrhage apparatus. Shock 32:172-78
    • (2009) Shock , vol.32 , pp. 172-178
    • Torres, A.1    Bentley, T.2    Bartels, J.3    Sarkar, J.4    Barclay, D.5
  • 8
    • 57849104348 scopus 로고    scopus 로고
    • Modeling endotoxin-induced systemic inflammation using an indirect response approach
    • Foteinou P, Calvano S, Lowry S, Androulakis I. 2009. Modeling endotoxin-induced systemic inflammation using an indirect response approach. Math. Biosci. 217:27-42
    • (2009) Math. Biosci , vol.217 , pp. 27-42
    • Foteinou, P.1    Calvano, S.2    Lowry, S.3    Androulakis, I.4
  • 9
    • 62849112761 scopus 로고    scopus 로고
    • In silico simulation of corticosteroids effect on an NFkB-Dependent physicochemical model of systemic inflammation
    • Foteinou PT, Calvano SE, Lowry SF, Androulakis IP. 2009. In silico simulation of corticosteroids effect on an NFkB-Dependent physicochemical model of systemic inflammation. PLoS ONE 4:e4706
    • (2009) PLoS ONE , vol.4
    • Foteinou, P.T.1    Calvano, S.E.2    Lowry, S.F.3    Androulakis, I.P.4
  • 10
    • 77953214777 scopus 로고    scopus 로고
    • Multiscale model for the assessment of autonomic dysfunction in human endotoxemia
    • Foteinou PT, Calvano SE, Lowry SF, Androulakis IP. 2010. Multiscale model for the assessment of autonomic dysfunction in human endotoxemia. Physiol. Genomics 42:5-19
    • (2010) Physiol. Genomics , vol.42 , pp. 5-19
    • Foteinou, P.T.1    Calvano, S.E.2    Lowry, S.F.3    Androulakis, I.P.4
  • 12
    • 79952163506 scopus 로고    scopus 로고
    • A physiological model for autonomic heart rate regulation in human endotoxemia
    • Foteinou PT, Calvano SE, Lowry SF, Androulakis IP. 2011. A physiological model for autonomic heart rate regulation in human endotoxemia. Shock 35:229-39
    • (2011) Shock , vol.35 , pp. 229-239
    • Foteinou, P.T.1    Calvano, S.E.2    Lowry, S.F.3    Androulakis, I.P.4
  • 13
    • 0037251105 scopus 로고    scopus 로고
    • Proteomics and systems biology approaches to signal transduction in sepsis
    • Nguyen A, YaffeMB. 2003. Proteomics and systems biology approaches to signal transduction in sepsis. Crit. Care Med. 31(Suppl. 1):S1-6
    • (2003) Crit. Care Med , vol.31 , Issue.SUPPL. 1
    • Nguyen, A.1    Yaffe, M.B.2
  • 14
    • 37249014081 scopus 로고    scopus 로고
    • The biological impact of mass-spectrometry-based proteomics
    • Cravatt BF, Simon GM, Yates JR III. 2007. The biological impact of mass-spectrometry-based proteomics. Nature 450:991-1000
    • (2007) Nature , vol.450 , pp. 991-1000
    • Cravatt, B.F.1    Simon, G.M.2    Yates Iii, J.R.3
  • 15
    • 0037435030 scopus 로고    scopus 로고
    • Mass spectrometry-based proteomics
    • Aebersold R, Mann M. 2003. Mass spectrometry-based proteomics. Nature 422:198-207
    • (2003) Nature , vol.422 , pp. 198-207
    • Aebersold, R.1    Mann, M.2
  • 16
    • 84855921201 scopus 로고    scopus 로고
    • Modeling signaling networks using high-Throughput phosphoproteomics
    • ed. II Goryanin, AB Goryachev, New York Springer
    • Terfve C, Saez-Rodriguez J. 2012. Modeling signaling networks using high-Throughput phosphoproteomics. In Advances in Systems Biology, ed. II Goryanin, AB Goryachev, pp. 19-57. New York: Springer
    • (2012) Advances in Systems Biology , pp. 19-57
    • Terfve, C.1    Saez-Rodriguez, J.2
  • 17
    • 80052364559 scopus 로고    scopus 로고
    • Analytical strategies in mass spectrometry-based phosphoproteomics
    • Rosenqvist H, Ye J, Jensen O. 2010. Analytical strategies in mass spectrometry-based phosphoproteomics. Methods Mol. Biol. 753:183-213
    • (2010) Methods Mol. Biol , vol.753 , pp. 183-213
    • Rosenqvist, H.1    Ye, J.2    Jensen, O.3
  • 18
    • 67651173106 scopus 로고    scopus 로고
    • Proteomics by mass spectrometry: Approaches, advances, and applications
    • Yates JR, Ruse CI, Nakorchevsky A. 2009. Proteomics by mass spectrometry: Approaches, advances, and applications. Annu. Rev. Biomed. Eng. 11:49-79
    • (2009) Annu. Rev. Biomed. Eng , vol.11 , pp. 49-79
    • Yates, J.R.1    Ruse, C.I.2    Nakorchevsky, A.3
  • 20
    • 84855572697 scopus 로고    scopus 로고
    • Mapping in vivo signal transduction defects by phosphoproteomics
    • Stasyk T, Huber LA. 2012. Mapping in vivo signal transduction defects by phosphoproteomics. Trends Mol. Med. 18:43-51
    • (2012) Trends Mol. Med , vol.18 , pp. 43-51
    • Stasyk, T.1    Huber, L.A.2
  • 21
    • 80755172538 scopus 로고    scopus 로고
    • Iterative in situ click chemistry assembles a branched capture agent and allosteric inhibitor for Akt1
    • Millward SW,Henning RK,Kwong GA, Pitram S, AgnewHD, et al. 2011. Iterative in situ click chemistry assembles a branched capture agent and allosteric inhibitor for Akt1. J. Am. Chem. Soc. 133:18280-88
    • (2011) J. Am. Chem. Soc , vol.133 , pp. 18280-18288
    • Millward, S.W.1    Henning, R.K.2    Kwong, G.A.3    Pitram Agnew, S.H.D.4
  • 22
    • 84855500163 scopus 로고    scopus 로고
    • An overview of Western blotting for determining antibody specificities for immunohistochemistry
    • Kurien BT, Dorri Y, Dillon S, Dsouza A, Scofield RH. 2011. An overview of Western blotting for determining antibody specificities for immunohistochemistry. Methods Mol. Biol. 717:55-67
    • (2011) Methods Mol. Biol , vol.717 , pp. 55-67
    • Kurien, B.T.1    Dorri, Y.2    Dillon, S.3    Dsouza, A.4    Scofield, R.H.5
  • 23
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli UK. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-85
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 24
    • 0030122080 scopus 로고    scopus 로고
    • Identification of glycoproteins on nitrocellulose membranes and gels
    • Thornton DJ, Carlstedt I, Sheehan JK. 1996. Identification of glycoproteins on nitrocellulose membranes and gels. Mol. Biotechnol. 5:171-76
    • (1996) Mol. Biotechnol , vol.5 , pp. 171-176
    • Thornton, D.J.1    Carlstedt, I.2    Sheehan, J.K.3
  • 27
    • 80054778378 scopus 로고    scopus 로고
    • Pi3k-dependent gsk3β(ser9)-phosphorylation is implicated in the intestinal epithelial cell wound-healing response
    • Karrasch T, Spaeth T, Allard B, Jobin C. 2011. PI3K-Dependent GSK3β(Ser9)-phosphorylation is implicated in the intestinal epithelial cell wound-healing response. PLoS One 6:e26340
    • (2011) PLoS One , vol.6
    • Karrasch, T.1    Spaeth, T.2    Allard, B.3    Jobin, C.4
  • 28
    • 80052761335 scopus 로고    scopus 로고
    • Type 2 diabetes is associated with altered nf-dna binding activity jnk phosphorylation and ampk phosphorylation in skeletal muscle after lps
    • Andreasen AS, Kelly M, Berg RM, Moller K, Pedersen BK. 2011. Type 2 diabetes is associated with altered NF-κB DNA binding activity, JNK phosphorylation, and AMPK phosphorylation in skeletal muscle after LPS. PLoS One 6:e23999
    • (2011) PLoS One , vol.6
    • Andreasen, A.S.1    Kelly, M.2    Berg, R.M.3    Moller, K.4    Pedersen, B.K.5
  • 29
    • 84862951708 scopus 로고    scopus 로고
    • In-Depth identification of pathways related to cisplatin-induced hepatotoxicity through an integrative method based on an informatics-Assisted labelfree protein quantitation and microarray gene expression approach
    • Cho YE, SinghTS, LeeHC, Moon PG, Lee JE, et al. 2012. In-Depth identification of pathways related to cisplatin-induced hepatotoxicity through an integrative method based on an informatics-Assisted labelfree protein quantitation and microarray gene expression approach. Mol. Cell. Proteomics 11:M111.010884
    • (2012) Mol. Cell. Proteomics , vol.11
    • Cho, Y.E.1    Singh, T.S.2    Lee, H.C.3    Moon, P.G.4    Lee, J.E.5
  • 30
    • 80055108726 scopus 로고    scopus 로고
    • Purification of specific cell population by fluorescence activated cell sorting (FACS)
    • Basu S, Campbell HM, Dittel BN, Ray A. 2010. Purification of specific cell population by fluorescence activated cell sorting (FACS). J. Vis. Exp. e1546
    • (2010) J. Vis. Exp
    • Basu, S.1    Campbell, H.M.2    Dittel, B.N.3    Ray, A.4
  • 32
    • 33645318725 scopus 로고    scopus 로고
    • Phospho-proteomic immune analysis by flow cytometry: From mechanism to translational medicine at the single-cell level
    • Perez OD, Nolan GP. 2006. Phospho-proteomic immune analysis by flow cytometry: From mechanism to translational medicine at the single-cell level. Immunol. Rev. 210:208-28
    • (2006) Immunol. Rev , vol.210 , pp. 208-228
    • Perez, O.D.1    Nolan, G.P.2
  • 33
    • 3242683662 scopus 로고    scopus 로고
    • Single cell profiling of potentiated phospho-protein networks in cancer cells
    • Irish JM, Hovland R, Krutzik PO, Perez OD, Bruserud Ø, et al. 2004. Single cell profiling of potentiated phospho-protein networks in cancer cells. Cell 118:217-28
    • (2004) Cell , vol.118 , pp. 217-228
    • Irish, J.M.1    Hovland, R.2    Krutzik, P.O.3    Perez, O.D.4    Bruserud Ø5
  • 34
    • 33644833555 scopus 로고    scopus 로고
    • Mapping normal and cancer cell signalling networks: Towards single-cell proteomics
    • Irish JM, Kotecha N, Nolan GP. 2006. Mapping normal and cancer cell signalling networks: Towards single-cell proteomics. Nat. Rev. Cancer 6:146-55
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 146-155
    • Irish, J.M.1    Kotecha, N.2    Nolan, G.P.3
  • 35
    • 17644427718 scopus 로고    scopus 로고
    • Causal protein-signaling networks derived from multiparameter single-cell data
    • Sachs K, Perez O, Pe'er D, Lauffenburger DA, Nolan GP. 2005. Causal protein-signaling networks derived from multiparameter single-cell data. Science 308:523-29
    • (2005) Science , vol.308 , pp. 523-529
    • Sachs, K.1    Perez, O.2    Pe'Er, D.3    Lauffenburger, D.A.4    Nolan, G.P.5
  • 37
    • 34547488563 scopus 로고    scopus 로고
    • A systems biology approach to the pathogenesis of obesity-related nonalcoholic fatty liver disease using reverse phase protein microarrays for multiplexed cell signaling analysis
    • Calvert VS, Collantes R, ElarinyH, Afendy A, Baranova A, et al. 2007. A systems biology approach to the pathogenesis of obesity-related nonalcoholic fatty liver disease using reverse phase protein microarrays for multiplexed cell signaling analysis. Hepatology 46:166-72
    • (2007) Hepatology , vol.46 , pp. 166-172
    • Calvert, V.S.1    Collantes, R.2    Elariny, H.3    Afendy, A.4    Baranova, A.5
  • 38
    • 84855643316 scopus 로고    scopus 로고
    • A dual array-based approach to assess the abundance and posttranslational modification state of signaling proteins
    • Erratum. 2012 Sci Signal 5:er5
    • Luckert K, Gujral TS, Chan M, Sevecka M, Joos TO, et al. 2012. A dual array-based approach to assess the abundance and posttranslational modification state of signaling proteins. Sci. Signal. 5:pl1; Erratum. 2012. Sci. Signal. 5:er5
    • (2012) Sci. Signal , vol.5
    • Luckert, K.1    Gujral, T.S.2    Chan, M.3    Sevecka, M.4    Joos, T.O.5
  • 39
    • 77956554551 scopus 로고    scopus 로고
    • Networks inferred from biochemical data reveal profound differences in TLR and inflammatory signaling between normal and transformed hepatocytes
    • Alexopoulos LG, Saez-Rodriguez J, Cosgrove BD, Lauffenburger DA, Sorger PK. 2010. Networks inferred from biochemical data reveal profound differences in TLR and inflammatory signaling between normal and transformed hepatocytes. Mol. Cell. Proteomics 9:1849-65
    • (2010) Mol. Cell. Proteomics , vol.9 , pp. 1849-1865
    • Alexopoulos, L.G.1    Saez-Rodriguez, J.2    Cosgrove, B.D.3    Lauffenburger, D.A.4    Sorger, P.K.5
  • 40
    • 79959816776 scopus 로고    scopus 로고
    • Combined logical and data-Driven models for linking signalling pathways to cellular response
    • Melas IN,Mitsos A,Messinis DE, Weiss TS, Alexopoulos LG. 2011. Combined logical and data-Driven models for linking signalling pathways to cellular response. BMC Syst. Biol. 5:107
    • (2011) BMC Syst. Biol , vol.5 , pp. 107
    • Melas, I.N.1    Mitsos, A.2    Messinis, D.E.3    Weiss, T.S.4    Alexopoulos, L.G.5
  • 41
    • 71449120701 scopus 로고    scopus 로고
    • Discrete logic modelling as a means to link protein signalling networks with functional analysis of mammalian signal transduction
    • Saez-Rodriguez J, Alexopoulos LG, Epperlein J, Samaga R, Lauffenburger DA, et al. 2009. Discrete logic modelling as a means to link protein signalling networks with functional analysis of mammalian signal transduction. Mol. Syst. Biol. 5:331
    • (2009) Mol. Syst. Biol , vol.5 , pp. 331
    • Saez-Rodriguez, J.1    Alexopoulos, L.G.2    Epperlein, J.3    Samaga, R.4    Lauffenburger, D.A.5
  • 42
    • 0842320458 scopus 로고    scopus 로고
    • A high-Throughput quantitative multiplex kinase assay for monitoring information flow in signaling networks: Application to sepsis-Apoptosis
    • Janes KA, Albeck JG, Peng LX, Sorger PK, Lauffenburger DA, Yaffe MB. 2003. A high-Throughput quantitative multiplex kinase assay for monitoring information flow in signaling networks: Application to sepsis-Apoptosis. Mol. Cell. Proteomics 2:463-73
    • (2003) Mol. Cell. Proteomics , vol.2 , pp. 463-473
    • Janes, K.A.1    Albeck, J.G.2    Peng, L.X.3    Sorger, P.K.4    Lauffenburger, D.A.5    Yaffe, M.B.6
  • 43
    • 34547623194 scopus 로고    scopus 로고
    • Common effector processing mediates cell-specific responses to stimuli
    • Miller-Jensen K, Janes KA, Brugge JS, Lauffenburger DA. 2007. Common effector processing mediates cell-specific responses to stimuli. Nature 448:604-8
    • (2007) Nature , vol.448 , pp. 604-608
    • Miller-Jensen, K.1    Janes, K.A.2    Brugge, J.S.3    Lauffenburger, D.A.4
  • 45
    • 62449088312 scopus 로고    scopus 로고
    • Differential expression of toll-like receptor genes: Sepsis compared with sterile inflammation 1 day before sepsis diagnosis
    • Lissauer ME, Johnson SB, Bochicchio GV, Feild CJ, Cross AS, et al. 2009. Differential expression of toll-like receptor genes: Sepsis compared with sterile inflammation 1 day before sepsis diagnosis. Shock 31:238-44
    • (2009) Shock , vol.31 , pp. 238-244
    • Lissauer, M.E.1    Johnson, S.B.2    Bochicchio, G.V.3    Feild, C.J.4    Cross, A.S.5
  • 46
    • 79961233440 scopus 로고    scopus 로고
    • A novel approach to exploring potential interactions among single-nucleotide polymorphisms of inflammation genes in gliomagenesis: An exploratory case-only study
    • Amirian ES, ScheurerME, Liu Y,D'Amelio AM,Houlston RS, et al. 2011. A novel approach to exploring potential interactions among single-nucleotide polymorphisms of inflammation genes in gliomagenesis: An exploratory case-only study. Cancer Epidemiol. Biomark. Prev. 20:1683-89
    • (2011) Cancer Epidemiol. Biomark. Prev , vol.20 , pp. 1683-1689
    • Amirian, E.S.1    Scheurer, M.E.2    Liu, Y.3    D'Amelio, A.M.4    Houlston, R.S.5
  • 47
    • 33644875750 scopus 로고    scopus 로고
    • Pstiing: A 'systems' approach towards integrating signalling pathways, interaction and transcriptional regulatory networks in inflammation and cancer
    • Ng A, Bursteinas B, Gao Q, Mollison E, Zvelebil M. 2006. pSTIING: A 'systems' approach towards integrating signalling pathways, interaction and transcriptional regulatory networks in inflammation and cancer. Nucleic Acids Res. 34:D527-34
    • (2006) Nucleic Acids Res , vol.34
    • Ng, A.1    Bursteinas, B.2    Gao, Q.3    Mollison, E.4    Zvelebil, M.5
  • 50
    • 58549083142 scopus 로고    scopus 로고
    • Input-output behavior of ErbB signaling pathways as revealed by a mass action model trained against dynamic data
    • Chen WW, Schoeberl B, Jasper PJ, Niepel M, Nielsen UB, et al. 2009. Input-output behavior of ErbB signaling pathways as revealed by a mass action model trained against dynamic data. Mol. Syst. Biol. 5:239
    • (2009) Mol. Syst. Biol , vol.5 , pp. 239
    • Chen, W.W.1    Schoeberl, B.2    Jasper, P.J.3    Niepel, M.4    Nielsen, U.B.5
  • 51
    • 84862617923 scopus 로고    scopus 로고
    • Assessment of linear regression techniques for modeling multisensor data for non-invasive continuous glucose monitoring
    • Zanon M, Riz M, Sparacino G, Facchinetti A, Suri RE, et al. 2011. Assessment of linear regression techniques for modeling multisensor data for non-invasive continuous glucose monitoring. Conf. Proc. IEEE Eng. Med. Biol. Soc. 2011:2538-41
    • (2011) Conf. Proc. IEEE Eng. Med. Biol. Soc , vol.2011 , pp. 2538-2541
    • Zanon, M.1    Riz, M.2    Sparacino, G.3    Facchinetti, A.4    Suri, R.E.5
  • 52
    • 79551503156 scopus 로고    scopus 로고
    • Linear regression analysis: Part 14 of a series on evaluation of scientific publications
    • Schneider A, Hommel G, Blettner M. 2010. Linear regression analysis: Part 14 of a series on evaluation of scientific publications. Dtsch. Arztebl. Int. 107:776-82
    • (2010) Dtsch. Arztebl. Int , vol.107 , pp. 776-782
    • Schneider, A.1    Hommel, G.2    Blettner, M.3
  • 53
    • 85027927447 scopus 로고    scopus 로고
    • A survey of current software for network analysis in molecular biology
    • Thomas S, Bonchev D. 2010. A survey of current software for network analysis in molecular biology. Hum. Genomics 4:353-60
    • (2010) Hum. Genomics , vol.4 , pp. 353-360
    • Thomas, S.1    Bonchev, D.2
  • 54
    • 51049117937 scopus 로고    scopus 로고
    • Models from experiments: Combinatorial drug perturbations of cancer cells
    • Nelander S,WangW, Nilsson B, She QB, Pratilas C, et al. 2008. Models from experiments: Combinatorial drug perturbations of cancer cells. Mol. Syst. Biol. 4:216
    • (2008) Mol. Syst. Biol , vol.4 , pp. 216
    • Nelander, S.1    Wang, W.2    Nilsson, B.3    She, Q.B.4    Pratilas, C.5
  • 55
  • 56
    • 33144460185 scopus 로고    scopus 로고
    • Dynamic regulation of pro-And antiinflammatory cytokines by MAPK phosphatase 1 (MKP-1) in innate immune responses
    • Chi H, Barry SP, Roth RJ, Wu JJ, Jones EA, et al. 2006. Dynamic regulation of pro-And antiinflammatory cytokines by MAPK phosphatase 1 (MKP-1) in innate immune responses. Proc. Natl. Acad. Sci. USA 103:2274-79
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 2274-2279
    • Chi, H.1    Barry, S.P.2    Roth, R.J.3    Wu, J.J.4    Jones, E.A.5
  • 57
    • 45349102367 scopus 로고    scopus 로고
    • Plasticity of the systemic inflammatory response to acute infection during critical illness: Development of the riboleukogram
    • McDunn JE, Husain KD, Polpitiya AD, Burykin A, Ruan J, et al. 2008. Plasticity of the systemic inflammatory response to acute infection during critical illness: Development of the riboleukogram. PLoS One 3:e1564
    • (2008) PLoS One , vol.3
    • McDunn, J.E.1    Husain, K.D.2    Polpitiya, A.D.3    Burykin, A.4    Ruan, J.5
  • 58
    • 34249660614 scopus 로고    scopus 로고
    • SOCS proteins, cytokine signalling and immune regulation
    • Yoshimura A, Naka T, Kubo M. 2007. SOCS proteins, cytokine signalling and immune regulation. Nat. Rev. Immunol. 7:454-65
    • (2007) Nat. Rev. Immunol , vol.7 , pp. 454-465
    • Yoshimura, A.1    Naka, T.2    Kubo, M.3
  • 60
    • 28844441230 scopus 로고    scopus 로고
    • A systems model of signaling identifies a molecular basis set for cytokine-induced apoptosis
    • Janes KA, Albeck JG, Gaudet S, Sorger PK, Lauffenburger DA, Yaffe MB. 2005. A systems model of signaling identifies a molecular basis set for cytokine-induced apoptosis. Science 310:1646-53
    • (2005) Science , vol.310 , pp. 1646-1653
    • Janes, K.A.1    Albeck, J.G.2    Gaudet, S.3    Sorger, P.K.4    Lauffenburger, D.A.5    Yaffe, M.B.6
  • 61
    • 0036256644 scopus 로고    scopus 로고
    • What does Stat3 do?
    • Levy DE, Lee CK. 2002. What does Stat3 do? J. Clin. Invest. 109:1143-48
    • (2002) J Clin. Invest , vol.109 , pp. 1143-1148
    • Levy, D.E.1    Lee, C.K.2
  • 62
    • 79960892156 scopus 로고    scopus 로고
    • Comparison of the cytokine and chemokine dynamics of the early inflammatory response in models of burn injury and infection
    • Orman MA, Nguyen TT, Ierapetritou MG, Berthiaume F, Androulakis IP. 2011. Comparison of the cytokine and chemokine dynamics of the early inflammatory response in models of burn injury and infection. Cytokine 55:362-71
    • (2011) Cytokine , vol.55 , pp. 362-371
    • Orman, M.A.1    Nguyen, T.T.2    Ierapetritou, M.G.3    Berthiaume, F.4    Androulakis, I.P.5
  • 63
    • 0029118395 scopus 로고
    • IL-10 induces the tyrosine phosphorylation of tyk2 and Jak1 and the differential assembly of STAT1 alpha and STAT3 complexes in human T cells and monocytes
    • Finbloom DS, Winestock KD. 1995. IL-10 induces the tyrosine phosphorylation of tyk2 and Jak1 and the differential assembly of STAT1 alpha and STAT3 complexes in human T cells and monocytes. J. Immunol. 155:1079-90
    • (1995) J. Immunol , vol.155 , pp. 1079-1090
    • Finbloom, D.S.1    Winestock, K.D.2
  • 66
    • 0025213189 scopus 로고
    • Effect of gramnegative endotoxin on levels of serum corticosterone, TNFalpha, circulating blood cells, and the survival of rats
    • Feuerstein G, Hallenbeck JM, Vanatta B, Rabinovici R, Perera PY, Vogel SN. 1990. Effect of gramnegative endotoxin on levels of serum corticosterone,TNFalpha, circulating blood cells, and the survival of rats. Circ. Shock 30:265-78
    • (1990) Circ. Shock , vol.30 , pp. 265-278
    • Feuerstein, G.1    Hallenbeck, J.M.2    Vanatta, B.3    Rabinovici, R.4    Perera, P.Y.5    Vogel, S.N.6
  • 68
    • 67949101916 scopus 로고    scopus 로고
    • Endocytosis and signalling: A meeting with mathematics
    • Birtwistle MR, Kholodenko BN. 2009. Endocytosis and signalling: A meeting with mathematics. Mol. Oncol. 3:308-20
    • (2009) Mol. Oncol , vol.3 , pp. 308-320
    • Birtwistle, M.R.1    Kholodenko, B.N.2
  • 69
    • 0029790351 scopus 로고    scopus 로고
    • Ultrasensitivity in the mitogen-Activated protein kinase cascade
    • Huang CY, Ferrell JE Jr. 1996. Ultrasensitivity in the mitogen-Activated protein kinase cascade. Proc. Natl. Acad. Sci. USA 93:10078-83
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 10078-10083
    • Huang, C.Y.1    Ferrell Jr., J.E.2
  • 71
    • 55749093996 scopus 로고    scopus 로고
    • Network inference using informative priors
    • Mukherjee S, Speed TP. 2008. Network inference using informative priors. Proc. Natl. Acad. Sci. 105:14313-18
    • (2008) Proc. Natl. Acad. Sci , vol.105 , pp. 14313-14318
    • Mukherjee, S.1    Speed, T.P.2
  • 72
    • 0036207347 scopus 로고    scopus 로고
    • Modeling and simulation of genetic regulatory systems: A literature review
    • de Jong H. 2002. Modeling and simulation of genetic regulatory systems: A literature review. J. Comput. Biol. 9:67-103
    • (2002) J. Comput. Biol , vol.9 , pp. 67-103
    • De Jong, H.1
  • 73
    • 33746190736 scopus 로고    scopus 로고
    • Circulating cytokine/inhibitor profiles reshape the understanding of the SIRS/CARS continuum in sepsis and predict mortality
    • OsuchowskiMF, Welch K, Siddiqui J, Remick DG. 2006. Circulating cytokine/inhibitor profiles reshape the understanding of the SIRS/CARS continuum in sepsis and predict mortality. J. Immunol. 177:1967-74
    • (2006) J. Immunol , vol.177 , pp. 1967-1974
    • Osuchowski, M.F.1    Welch, K.2    Siddiqui, J.3    Remick, D.G.4
  • 74
    • 0035066383 scopus 로고    scopus 로고
    • Mammalian mitogen-Activated protein kinase signal transduction pathways activated by stress and inflammation
    • Kyriakis JM, Avruch J. 2001. Mammalian mitogen-Activated protein kinase signal transduction pathways activated by stress and inflammation. Physiol. Rev. 81:807-69
    • (2001) Physiol. Rev , vol.81 , pp. 807-869
    • Kyriakis, J.M.1    Avruch, J.2
  • 75
    • 0014671878 scopus 로고
    • Homeostasis and differentiation in random genetic control networks
    • Kauffman S. 1969. Homeostasis and differentiation in random genetic control networks. Nature 224:177-78
    • (1969) Nature , vol.224 , pp. 177-178
    • Kauffman, S.1
  • 78
    • 0026366218 scopus 로고
    • Neural-network-based fuzzy logic control and decision system
    • Lin CT, Lee CSG. 1991. Neural-network-based fuzzy logic control and decision system. Comput. IEEE Trans. 40:1320-36
    • (1991) Comput. IEEE Trans , vol.40 , pp. 1320-1336
    • Lin, C.T.1    Lee, C.S.G.2
  • 79
    • 0033607313 scopus 로고    scopus 로고
    • TheNF-κB activation pathway: A paradigm in information transfer from membrane to nucleus
    • Rothwarf DM, Karin M. 1999. TheNF-κB activation pathway: A paradigm in information transfer from membrane to nucleus. Sci. STKE 1999:re1
    • (1999) Sci. STKE , vol.1999
    • Rothwarf, D.M.1    Karin, M.2
  • 80
    • 79953668247 scopus 로고    scopus 로고
    • Training signaling pathwaymaps to biochemical data with constrained fuzzy logic: Quantitative analysis of liver cell responses to inflammatory stimuli
    • Morris MK, Saez-Rodriguez J, Clarke DC, Sorger PK, Lauffenburger DA. 2011. Training signaling pathwaymaps to biochemical data with constrained fuzzy logic: Quantitative analysis of liver cell responses to inflammatory stimuli. PLoS Comput. Biol. 7:e1001099
    • (2011) PLoS Comput. Biol , vol.7
    • Morris, M.K.1    Saez-Rodriguez, J.2    Clarke, D.C.3    Sorger, P.K.4    Lauffenburger, D.A.5
  • 82
    • 79953102845 scopus 로고    scopus 로고
    • In vivo systems analysis identifies spatial and temporal aspects of the modulation of TNF-Alpha-induced apoptosis and proliferation by MAPKs
    • Lau KS, Juchheim AM, Cavaliere KR, Philips SR, Lauffenburger DA, Haigis KM. 2011. In vivo systems analysis identifies spatial and temporal aspects of the modulation of TNF-Alpha-induced apoptosis and proliferation by MAPKs. Sci. Signal. 4:ra16
    • (2011) Sci. Signal , vol.4
    • Lau, K.S.1    Juchheim, A.M.2    Cavaliere, K.R.3    Philips, S.R.4    Lauffenburger, D.A.5    Haigis, K.M.6
  • 84
    • 33845866857 scopus 로고    scopus 로고
    • Inflammation and metabolic disorders
    • Hotamisligil GS. 2006. Inflammation and metabolic disorders. Nature 444:860-67
    • (2006) Nature , vol.444 , pp. 860-867
    • Hotamisligil, G.S.1
  • 85
    • 0027272248 scopus 로고
    • Interleukin-1 receptor antagonist improves survival and preserves organ adenosine-5-Triphosphate after hemorrhagic shock
    • Pellicane JV, DeMaria EJ, Abd-Elfattah A, Reines HD, Vannice JL, Carson KW. 1993. Interleukin-1 receptor antagonist improves survival and preserves organ adenosine-5--Triphosphate after hemorrhagic shock. Surgery 114:278-84
    • (1993) Surgery , vol.114 , pp. 278-284
    • Pellicane, J.V.1    Demaria, E.J.2    Abd-Elfattah, A.3    Reines, H.D.4    Vannice, J.L.5    Carson, K.W.6
  • 88
    • 0031434418 scopus 로고    scopus 로고
    • Interleukin-10: Biology, role in inflammation and autoimmunity
    • Lalani I, Bhol K, Ahmed AR. 1997. Interleukin-10: Biology, role in inflammation and autoimmunity. Ann. Allergy Asthma Immunol. 79:469-84
    • (1997) Ann. Allergy Asthma Immunol , vol.79 , pp. 469-484
    • Lalani, I.1    Bhol, K.2    Ahmed, A.R.3
  • 90
    • 70350517075 scopus 로고    scopus 로고
    • Deciphering signaling outcomes from a system of complex networks
    • Hsueh RC, Natarajan M, Fraser I, Pond B, Liu J, et al. 2009. Deciphering signaling outcomes from a system of complex networks. Sci. Signal. 2:ra22
    • (2009) Sci. Signal , vol.2
    • Hsueh, R.C.1    Natarajan, M.2    Fraser, I.3    Pond, B.4    Liu, J.5
  • 91
    • 34249696885 scopus 로고    scopus 로고
    • The effect of iNOS deletion on hepatic gluconeogenesis in hyperdynamic murine septic shock
    • Albuszies G, Vogt J, Wachter U, Thiemermann C, Leverve X, et al. 2007. The effect of iNOS deletion on hepatic gluconeogenesis in hyperdynamic murine septic shock. Intensive Care Med. 33:1094-101
    • (2007) Intensive Care Med , vol.33 , pp. 1094-1101
    • Albuszies, G.1    Vogt, J.2    Wachter, U.3    Thiemermann, C.4    Leverve, X.5
  • 92
    • 79961061340 scopus 로고    scopus 로고
    • C1-inhibitor: More than a serine protease inhibitor
    • Zeerleder S. 2010. C1-inhibitor: More than a serine protease inhibitor. Semin. Thromb. Hemost. 37:362-74
    • (2010) Semin. Thromb. Hemost , vol.37 , pp. 362-374
    • Zeerleder, S.1
  • 94
    • 79955159111 scopus 로고    scopus 로고
    • Protective cross talk between activated protein C and TNF signaling in vascular endothelial cells: Implication of EPCR, noncanonical NF-κB, and ERK1/2 MAP kinases
    • Guitton C, Cottereau A, Ǵerard N, Quillard T, Chauveau A, et al. 2010. Protective cross talk between activated protein C and TNF signaling in vascular endothelial cells: Implication of EPCR, noncanonical NF-κB, and ERK1/2 MAP kinases. Am. J. Physiol.: Cell Physiol. 300:C833-42
    • (2010) Am. J. Physiol.: Cell Physiol , vol.300
    • Guitton, C.1    Cottereau, A.2    Ǵerard, N.3    Quillard, T.4    Chauveau, A.5
  • 95
    • 84861468039 scopus 로고    scopus 로고
    • Clinical proteomics and OMICS clues useful in translational medicine research
    • Lopez E, Madero L, Lopez-Pascual J, Latterich M. 2012. Clinical proteomics and OMICS clues useful in translational medicine research. Proteome Sci. 10:35
    • (2012) Proteome Sci , vol.10 , pp. 35
    • Lopez, E.1    Madero, L.2    Lopez-Pascual, J.3    Latterich, M.4
  • 96
    • 33645934802 scopus 로고    scopus 로고
    • Translational proteomics: Developing a predictive capacity -A review
    • Suppl
    • Rice GE, Georgiou HM, Ahmed N, Shi G, Kruppa G. 2006. Translational proteomics: Developing a predictive capacity -A review. Placenta 27(Suppl.):76-86
    • (2006) Placenta , vol.27 , pp. 76-86
    • Rice, G.E.1    Georgiou, H.M.2    Ahmed, N.3    Shi, G.4    Kruppa, G.5
  • 97
    • 33847651237 scopus 로고    scopus 로고
    • Proteomics in clinical interventions: Achievements and limitations in biomarker development
    • Sinha A, Singh C, Parmar D, Singh MP. 2007. Proteomics in clinical interventions: Achievements and limitations in biomarker development. Life Sci. 80:1345-54
    • (2007) Life Sci , vol.80 , pp. 1345-1354
    • Sinha, A.1    Singh, C.2    Parmar, D.3    Singh, M.P.4
  • 100
    • 84864247996 scopus 로고    scopus 로고
    • Computational and systems biology in trauma and sepsis: Current state and future perspectives
    • An G, Nieman G, Vodovotz Y. 2012. Computational and systems biology in trauma and sepsis: Current state and future perspectives. Int. J. Burns Trauma 2:1-10
    • (2012) Int. J. Burns Trauma , vol.2 , pp. 1-10
    • An, G.1    Nieman, G.2    Vodovotz, Y.3
  • 102
    • 84861199459 scopus 로고    scopus 로고
    • Sepsis: Something old, something new, and a systems view
    • Namas R, Zamora R, Namas R, An G, Doyle J, et al. 2012. Sepsis: Something old, something new, and a systems view. J. Crit. Care 27:314.e1-e11
    • (2012) J. Crit. Care , vol.27 , Issue.314
    • Namas, R.1    Zamora, R.2    Namas, R.3    An, G.4    Doyle, J.5
  • 103
    • 84863338100 scopus 로고    scopus 로고
    • A two-compartment mathematical model of endotoxin-induced inflammatory and physiologic alterations in swine
    • Nieman G, BrownD, Sarkar J,Kubiak B, ZiraldoC, et al. 2012. A two-compartment mathematical model of endotoxin-induced inflammatory and physiologic alterations in swine. Crit. Care Med. 40:1052-63
    • (2012) Crit. Care Med , vol.40 , pp. 1052-1063
    • Nieman, G.1    Brown, D.2    Sarkar, J.3    Kubiak, B.4    Ziraldo, C.5
  • 107
    • 77950667827 scopus 로고    scopus 로고
    • Subcellular quantitative proteomics reveals multiple pathway cross-Talk that coordinates specific signaling and transcriptional regulation for the early host response to LPS
    • Du R, Long J, Yao J, Dong Y, Yang X, et al. 2010. Subcellular quantitative proteomics reveals multiple pathway cross-Talk that coordinates specific signaling and transcriptional regulation for the early host response to LPS. J. Proteome Res. 9:1805-21
    • (2010) J. Proteome Res , vol.9 , pp. 1805-1821
    • Du, R.1    Long, J.2    Yao, J.3    Dong, Y.4    Yang, X.5


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