Causal protein-signaling networks derived from multiparameter single-cell data

Science

Volumn 308, Issue 5721, 2005, Pages 523-529

  Sachs, Karen ^a   Perez, Omar ^b   Pe'er, Dana ^c   Lauffenburger, Douglas A ^a   Nolan, Garry P ^b  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; COMPUTATIONAL METHODS; IMMUNOLOGY; LEARNING SYSTEMS; PHOSPHOLIPIDS; PHYSIOLOGICAL MODELS; SIGNALING; TISSUE;

CELLULAR SIGNALING NETWORKS; COMPLEX DRUG ACTIONS; HUMAN IMMUNE SYSTEM CELLS; NETWORK MODELS;

PROTEINS;

PHOSPHOLIPID; PROTEIN;

BIOCHEMISTRY; BIOLOGY;

ACCURACY; ARTICLE; AUTOMATION; BAYES THEOREM; DERIVATIZATION; IMMUNOCOMPETENT CELL; MATHEMATICAL COMPUTING; PREDICTION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

ALGORITHMS; ARTIFICIAL INTELLIGENCE; BAYES THEOREM; CD4-POSITIVE T-LYMPHOCYTES; CYCLIC AMP-DEPENDENT PROTEIN KINASES; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLOW CYTOMETRY; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MATHEMATICS; MODELS, BIOLOGICAL; PHOSPHOLIPIDS; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN KINASE C; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

EID: 17644427718     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1105809     Document Type: Article

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