-
1
-
-
0034958947
-
Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care
-
Angus D.C., Linde-Zwirble W.T., Lidicker J., et al. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit Care Med 2001, 29:1303-1310.
-
(2001)
Crit Care Med
, vol.29
, pp. 1303-1310
-
-
Angus, D.C.1
Linde-Zwirble, W.T.2
Lidicker, J.3
-
2
-
-
0037451929
-
The epidemiology of sepsis in the United States from 1979 through 2000
-
Martin G.S., Mannino D.M., Eaton S., et al. The epidemiology of sepsis in the United States from 1979 through 2000. N Engl J Med 2003, 348:1546-1554.
-
(2003)
N Engl J Med
, vol.348
, pp. 1546-1554
-
-
Martin, G.S.1
Mannino, D.M.2
Eaton, S.3
-
3
-
-
31344461826
-
Sepsis in European intensive care units: results of the SOAP study
-
Vincent J.L., Sakr Y., Sprung C.L., et al. Sepsis in European intensive care units: results of the SOAP study. Crit Care Med 2006, 34:344-353.
-
(2006)
Crit Care Med
, vol.34
, pp. 344-353
-
-
Vincent, J.L.1
Sakr, Y.2
Sprung, C.L.3
-
5
-
-
0042832200
-
Long-term mortality and medical care charges in patients with severe sepsis
-
Weycker D., Akhras K.S., Edelsberg J., et al. Long-term mortality and medical care charges in patients with severe sepsis. Crit Care Med 2003, 31:2316-2323.
-
(2003)
Crit Care Med
, vol.31
, pp. 2316-2323
-
-
Weycker, D.1
Akhras, K.S.2
Edelsberg, J.3
-
6
-
-
0033590515
-
Treating patients with severe sepsis
-
Wheeler A.P., Bernard G.R. Treating patients with severe sepsis. N Engl J Med 1999, 340:207-214.
-
(1999)
N Engl J Med
, vol.340
, pp. 207-214
-
-
Wheeler, A.P.1
Bernard, G.R.2
-
7
-
-
0034924156
-
Epidemiology of sepsis: an update
-
Angus D.C., Wax R.S. Epidemiology of sepsis: an update. Crit Care Med 2001, 29:S109-S116.
-
(2001)
Crit Care Med
, vol.29
-
-
Angus, D.C.1
Wax, R.S.2
-
8
-
-
0030854780
-
Epidemiology of sepsis syndrome in 8 academic medical centers
-
Sands K.E., Bates D.W., Lanken P.N., et al. Epidemiology of sepsis syndrome in 8 academic medical centers. JAMA 1997, 278:234-240.
-
(1997)
JAMA
, vol.278
, pp. 234-240
-
-
Sands, K.E.1
Bates, D.W.2
Lanken, P.N.3
-
10
-
-
0025710312
-
Increase in National Hospital Discharge Survey rates for septicemia-United States, 1979-1987
-
Increase in National Hospital Discharge Survey rates for septicemia-United States, 1979-1987. MMWR Morb Mortal Wkly Rep 1990, 39:31-34.
-
(1990)
MMWR Morb Mortal Wkly Rep
, vol.39
, pp. 31-34
-
-
-
11
-
-
0033710233
-
Long-term health-related quality of life in survivors of sepsis. Short Form 36: a valid and reliable measure of health-related quality of life
-
Heyland D.K., Hopman W., Coo H., et al. Long-term health-related quality of life in survivors of sepsis. Short Form 36: a valid and reliable measure of health-related quality of life. Crit Care Med 2000, 28:3599-3605.
-
(2000)
Crit Care Med
, vol.28
, pp. 3599-3605
-
-
Heyland, D.K.1
Hopman, W.2
Coo, H.3
-
12
-
-
0029115513
-
Long-term survival and function after suspected gram-negative sepsis
-
Perl T.M., Dvorak L., Hwang T., et al. Long-term survival and function after suspected gram-negative sepsis. JAMA 1995, 274:338-345.
-
(1995)
JAMA
, vol.274
, pp. 338-345
-
-
Perl, T.M.1
Dvorak, L.2
Hwang, T.3
-
13
-
-
34447623219
-
Bench-to-bedside review: potential strategies to protect or reverse mitochondrial dysfunction in sepsis-induced organ failure
-
Protti A., Singer M. Bench-to-bedside review: potential strategies to protect or reverse mitochondrial dysfunction in sepsis-induced organ failure. Crit Care 2006, 10:228.
-
(2006)
Crit Care
, vol.10
, pp. 228
-
-
Protti, A.1
Singer, M.2
-
14
-
-
68049089963
-
Microcirculation and mitochondria in sepsis: getting out of breath
-
Balestra G.M., Legrand M., Ince C. Microcirculation and mitochondria in sepsis: getting out of breath. Curr Opin Anaesthesiol 2009, 22:184-190.
-
(2009)
Curr Opin Anaesthesiol
, vol.22
, pp. 184-190
-
-
Balestra, G.M.1
Legrand, M.2
Ince, C.3
-
15
-
-
0037588986
-
The role of the endothelium in severe sepsis and multiple organ dysfunction syndrome
-
Aird W.C. The role of the endothelium in severe sepsis and multiple organ dysfunction syndrome. Blood 2003, 101:3765-3777.
-
(2003)
Blood
, vol.101
, pp. 3765-3777
-
-
Aird, W.C.1
-
16
-
-
77956258291
-
The endothelium: physiological functions and role in microcirculatory failure during severe sepsis
-
Ait-Oufella H., Maury E., Lehoux S., et al. The endothelium: physiological functions and role in microcirculatory failure during severe sepsis. Intensive Care Med 2010, 36:1286-1298.
-
(2010)
Intensive Care Med
, vol.36
, pp. 1286-1298
-
-
Ait-Oufella, H.1
Maury, E.2
Lehoux, S.3
-
19
-
-
33751552449
-
Historical perspective of the word "sepsis"
-
Geroulanos S., Douka E.T. Historical perspective of the word "sepsis". Intensive Care Med 2006, 32:2077.
-
(2006)
Intensive Care Med
, vol.32
, pp. 2077
-
-
Geroulanos, S.1
Douka, E.T.2
-
21
-
-
53549101646
-
Clinical sepsis and septic shock-definition, diagnosis and management principles
-
Vincent J.L. Clinical sepsis and septic shock-definition, diagnosis and management principles. Langenbecks Arch Surg 2008, 393:817-824.
-
(2008)
Langenbecks Arch Surg
, vol.393
, pp. 817-824
-
-
Vincent, J.L.1
-
22
-
-
0000372097
-
Wesen und Behandlung der Sepsis
-
Schottmueller H. Wesen und Behandlung der Sepsis. Inn Med 2009, 31:257-280.
-
(2009)
Inn Med
, vol.31
, pp. 257-280
-
-
Schottmueller, H.1
-
23
-
-
0035491584
-
Agent-based computer simulation and sirs: building a bridge between basic science and clinical trials
-
An G. Agent-based computer simulation and sirs: building a bridge between basic science and clinical trials. Shock 2001, 16:266-273.
-
(2001)
Shock
, vol.16
, pp. 266-273
-
-
An, G.1
-
24
-
-
0035489972
-
Complex systems analysis: a tool for shock research
-
Buchman T.G., Cobb J.P., Lapedes A.S., et al. Complex systems analysis: a tool for shock research. Shock 2001, 16:248-251.
-
(2001)
Shock
, vol.16
, pp. 248-251
-
-
Buchman, T.G.1
Cobb, J.P.2
Lapedes, A.S.3
-
25
-
-
0036500993
-
Systems biology: a brief overview
-
Kitano H. Systems biology: a brief overview. Science 2002, 295:1662-1664.
-
(2002)
Science
, vol.295
, pp. 1662-1664
-
-
Kitano, H.1
-
26
-
-
0035486687
-
Complexity and non-linearity in shock research: reductionism or synthesis?
-
Neugebauer E.A., Willy C., Sauerland S. Complexity and non-linearity in shock research: reductionism or synthesis?. Shock 2001, 16:252-258.
-
(2001)
Shock
, vol.16
, pp. 252-258
-
-
Neugebauer, E.A.1
Willy, C.2
Sauerland, S.3
-
27
-
-
0036363170
-
Sepsis research in the next millennium: concentrate on the software rather than the hardware
-
Tjardes T., Neugebauer E. Sepsis research in the next millennium: concentrate on the software rather than the hardware. Shock 2002, 17:1-8.
-
(2002)
Shock
, vol.17
, pp. 1-8
-
-
Tjardes, T.1
Neugebauer, E.2
-
28
-
-
4744342992
-
Mathematical models of the acute inflammatory response
-
Vodovotz Y., Clermont G., Chow C., et al. Mathematical models of the acute inflammatory response. Curr Opin Crit Care 2004, 10:383-390.
-
(2004)
Curr Opin Crit Care
, vol.10
, pp. 383-390
-
-
Vodovotz, Y.1
Clermont, G.2
Chow, C.3
-
30
-
-
77956642489
-
Identification of complex metabolic states in critically injured patients using bioinformatic cluster analysis
-
Cohen M.J., Grossman A.D., Morabito D., et al. Identification of complex metabolic states in critically injured patients using bioinformatic cluster analysis. Crit Care 2010, 14:R10.
-
(2010)
Crit Care
, vol.14
-
-
Cohen, M.J.1
Grossman, A.D.2
Morabito, D.3
-
31
-
-
4744344132
-
In-silico experiments of existing and hypothetical cytokine-directed clinical trials using agent based modeling
-
An G. In-silico experiments of existing and hypothetical cytokine-directed clinical trials using agent based modeling. Crit Care Med 2004, 32:2050-2060.
-
(2004)
Crit Care Med
, vol.32
, pp. 2050-2060
-
-
An, G.1
-
32
-
-
0025081130
-
Host responses in mediating sepsis and adult respiratory distress syndrome
-
Strieter R.M., Lynch J.P., Basha M.A., et al. Host responses in mediating sepsis and adult respiratory distress syndrome. Semin Respir Infect 1990, 5:233-247.
-
(1990)
Semin Respir Infect
, vol.5
, pp. 233-247
-
-
Strieter, R.M.1
Lynch, J.P.2
Basha, M.A.3
-
33
-
-
0026874127
-
American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis
-
American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med 1992, 20:864-874.
-
(1992)
Crit Care Med
, vol.20
, pp. 864-874
-
-
-
34
-
-
0037389094
-
2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference
-
Levy M.M., Fink M.P., Marshall J.C., et al. 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference. Crit Care Med 2003, 31:1250-1256.
-
(2003)
Crit Care Med
, vol.31
, pp. 1250-1256
-
-
Levy, M.M.1
Fink, M.P.2
Marshall, J.C.3
-
35
-
-
0026710191
-
Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine
-
Bone R.C., Balk R.A., Cerra F.B., et al. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine. Chest 1992, 101:1644-1655.
-
(1992)
Chest
, vol.101
, pp. 1644-1655
-
-
Bone, R.C.1
Balk, R.A.2
Cerra, F.B.3
-
36
-
-
0036162008
-
Functional genomics of critical illness and injury
-
Chung T.P., Laramie J.M., Province M., et al. Functional genomics of critical illness and injury. Crit Care Med 2002, 30:S51-S57.
-
(2002)
Crit Care Med
, vol.30
-
-
Chung, T.P.1
Laramie, J.M.2
Province, M.3
-
37
-
-
2942678943
-
Injury research in the genomic era
-
Cobb J.P., O'Keefe G.E. Injury research in the genomic era. Lancet 2004, 363:2076-2083.
-
(2004)
Lancet
, vol.363
, pp. 2076-2083
-
-
Cobb, J.P.1
O'Keefe, G.E.2
-
38
-
-
0029893535
-
Uncoupling of biological oscillators: a complementary hypothesis concerning the pathogenesis of multiple organ dysfunction syndrome
-
Godin P.J., Buchman T.G. Uncoupling of biological oscillators: a complementary hypothesis concerning the pathogenesis of multiple organ dysfunction syndrome. Crit Care Med 1996, 24:1107-1116.
-
(1996)
Crit Care Med
, vol.24
, pp. 1107-1116
-
-
Godin, P.J.1
Buchman, T.G.2
-
39
-
-
4744375394
-
Nonlinear dynamics, complex systems, and the pathobiology of critical illness
-
Buchman T.G. Nonlinear dynamics, complex systems, and the pathobiology of critical illness. Curr Opin Crit Care 2004, 10:378-382.
-
(2004)
Curr Opin Crit Care
, vol.10
, pp. 378-382
-
-
Buchman, T.G.1
-
40
-
-
11344256331
-
Complex systems and the technology of variability analysis
-
Seely A.J., Macklem P.T. Complex systems and the technology of variability analysis. Crit Care 2004, 8:R367-R384.
-
(2004)
Crit Care
, vol.8
-
-
Seely, A.J.1
Macklem, P.T.2
-
41
-
-
43249089766
-
Translational systems biology of inflammation
-
Vodovotz Y., Csete M., Bartels J., et al. Translational systems biology of inflammation. PLoS Comput Biol 2008, 4:1-6.
-
(2008)
PLoS Comput Biol
, vol.4
, pp. 1-6
-
-
Vodovotz, Y.1
Csete, M.2
Bartels, J.3
-
42
-
-
57749172576
-
Mechanistic simulations of inflammation: current state and future prospects
-
Vodovotz Y., Constantine G., Rubin J., et al. Mechanistic simulations of inflammation: current state and future prospects. Math Biosci 2009, 217:1-10.
-
(2009)
Math Biosci
, vol.217
, pp. 1-10
-
-
Vodovotz, Y.1
Constantine, G.2
Rubin, J.3
-
43
-
-
54149112976
-
Biomarkers: diagnosis and risk assessment in sepsis
-
vii
-
Ventetuolo C.E., Levy M.M. Biomarkers: diagnosis and risk assessment in sepsis. Clin Chest Med 2008, 29:591-603. vii.
-
(2008)
Clin Chest Med
, vol.29
, pp. 591-603
-
-
Ventetuolo, C.E.1
Levy, M.M.2
-
44
-
-
77951056974
-
Approaching clinical reality: markers for monitoring systemic inflammation and sepsis
-
Claus R.A., Otto G.P., Deigner H.P., et al. Approaching clinical reality: markers for monitoring systemic inflammation and sepsis. Curr Mol Med 2010, 10:227-235.
-
(2010)
Curr Mol Med
, vol.10
, pp. 227-235
-
-
Claus, R.A.1
Otto, G.P.2
Deigner, H.P.3
-
45
-
-
0030843156
-
Sepsis: a new hypothesis for pathogenesis of the disease process
-
Bone R.C., Grodzin C.J., Balk R.A. Sepsis: a new hypothesis for pathogenesis of the disease process. Chest 1997, 112:235-243.
-
(1997)
Chest
, vol.112
, pp. 235-243
-
-
Bone, R.C.1
Grodzin, C.J.2
Balk, R.A.3
-
47
-
-
59649117667
-
Molecular biology of inflammation and sepsis: a primer
-
Cinel I., Opal S.M. Molecular biology of inflammation and sepsis: a primer. Crit Care Med 2009, 37:291-304.
-
(2009)
Crit Care Med
, vol.37
, pp. 291-304
-
-
Cinel, I.1
Opal, S.M.2
-
48
-
-
33747341838
-
In silico models of acute inflammation in animals
-
Vodovotz Y., Chow C.C., Bartels J., et al. In silico models of acute inflammation in animals. Shock 2006, 26:235-244.
-
(2006)
Shock
, vol.26
, pp. 235-244
-
-
Vodovotz, Y.1
Chow, C.C.2
Bartels, J.3
-
49
-
-
77957580213
-
Translational systems biology of inflammation: potential applications to personalized medicine
-
Mi Q., Li N.Y.K., Ziraldo C., et al. Translational systems biology of inflammation: potential applications to personalized medicine. Personalized Med 2010, 7:549-559.
-
(2010)
Personalized Med
, vol.7
, pp. 549-559
-
-
Mi, Q.1
Li, N.Y.K.2
Ziraldo, C.3
-
50
-
-
77949531330
-
An adequately robust early TNF-a response is a hallmark of survival following trauma/hemorrhage
-
Namas R., Ghuma A., Torres A., et al. An adequately robust early TNF-a response is a hallmark of survival following trauma/hemorrhage. PLoS ONE 2009, 4:e8406.
-
(2009)
PLoS ONE
, vol.4
-
-
Namas, R.1
Ghuma, A.2
Torres, A.3
-
51
-
-
0037426726
-
The pathophysiology and treatment of sepsis
-
Hotchkiss R.S., Karl I.E. The pathophysiology and treatment of sepsis. N Engl J Med 2003, 348:138-150.
-
(2003)
N Engl J Med
, vol.348
, pp. 138-150
-
-
Hotchkiss, R.S.1
Karl, I.E.2
-
52
-
-
15244341423
-
Epithelial barrier dysfunction: a unifying theme to explain the pathogenesis of multiple organ dysfunction at the cellular level
-
Fink M.P., Delude R.L. Epithelial barrier dysfunction: a unifying theme to explain the pathogenesis of multiple organ dysfunction at the cellular level. Crit Care Clin 2005, 21:177-196.
-
(2005)
Crit Care Clin
, vol.21
, pp. 177-196
-
-
Fink, M.P.1
Delude, R.L.2
-
53
-
-
0034919862
-
Inflammation, coagulopathy, and the pathogenesis of multiple organ dysfunction syndrome
-
Marshall J.C. Inflammation, coagulopathy, and the pathogenesis of multiple organ dysfunction syndrome. Crit Care Med 2001, 29:S99-106.
-
(2001)
Crit Care Med
, vol.29
-
-
Marshall, J.C.1
-
54
-
-
0033258418
-
Organ dysfunction following hemorrhage and sepsis: mechanisms and therapeutic approaches (review)
-
Jarrar D., Chaudry I.H., Wang P. Organ dysfunction following hemorrhage and sepsis: mechanisms and therapeutic approaches (review). Int J Mol Med 1999, 4:575-583.
-
(1999)
Int J Mol Med
, vol.4
, pp. 575-583
-
-
Jarrar, D.1
Chaudry, I.H.2
Wang, P.3
-
55
-
-
48249138990
-
Sepsis: links between pathogen sensing and organ damage
-
Crouser E., Exline M., Knoell D., et al. Sepsis: links between pathogen sensing and organ damage. Curr Pharm Des 2008, 14:1840-1852.
-
(2008)
Curr Pharm Des
, vol.14
, pp. 1840-1852
-
-
Crouser, E.1
Exline, M.2
Knoell, D.3
-
56
-
-
33745847180
-
TLRs, NLRs and RLRs: a trinity of pathogen sensors that co-operate in innate immunity
-
Creagh E.M., O'Neill L.A. TLRs, NLRs and RLRs: a trinity of pathogen sensors that co-operate in innate immunity. Trends Immunol 2006, 27:352-357.
-
(2006)
Trends Immunol
, vol.27
, pp. 352-357
-
-
Creagh, E.M.1
O'Neill, L.A.2
-
57
-
-
0037066427
-
The danger model: a renewed sense of self
-
Matzinger P. The danger model: a renewed sense of self. Science 2002, 296:301-305.
-
(2002)
Science
, vol.296
, pp. 301-305
-
-
Matzinger, P.1
-
59
-
-
70350475286
-
The pathophysiology of septic shock
-
vii
-
Nduka O.O., Parrillo J.E. The pathophysiology of septic shock. Crit Care Clin 2009, 25:677-702. vii.
-
(2009)
Crit Care Clin
, vol.25
, pp. 677-702
-
-
Nduka, O.O.1
Parrillo, J.E.2
-
60
-
-
34347397197
-
Advances in pathogenesis and management of sepsis
-
Cinel I., Dellinger R.P. Advances in pathogenesis and management of sepsis. Curr Opin Infect Dis 2007, 20:345-352.
-
(2007)
Curr Opin Infect Dis
, vol.20
, pp. 345-352
-
-
Cinel, I.1
Dellinger, R.P.2
-
61
-
-
72949115274
-
Role of Toll-like receptors, NOD-like receptors and RIG-I-like receptors in endothelial cells and systemic infections
-
Opitz B., Eitel J., Meixenberger K., et al. Role of Toll-like receptors, NOD-like receptors and RIG-I-like receptors in endothelial cells and systemic infections. Thromb Haemost 2009, 102:1103-1109.
-
(2009)
Thromb Haemost
, vol.102
, pp. 1103-1109
-
-
Opitz, B.1
Eitel, J.2
Meixenberger, K.3
-
63
-
-
0036255629
-
Association between a genomic polymorphism within the CD14 locus and septic shock susceptibility and mortality rate
-
Gibot S., Cariou A., Drouet L., et al. Association between a genomic polymorphism within the CD14 locus and septic shock susceptibility and mortality rate. Crit Care Med 2002, 30:969-973.
-
(2002)
Crit Care Med
, vol.30
, pp. 969-973
-
-
Gibot, S.1
Cariou, A.2
Drouet, L.3
-
64
-
-
0041344362
-
Injury primes the innate immune system for enhanced Toll-like receptor reactivity
-
Paterson H.M., Murphy T.J., Purcell E.J., et al. Injury primes the innate immune system for enhanced Toll-like receptor reactivity. J Immunol 2003, 171:1473-1483.
-
(2003)
J Immunol
, vol.171
, pp. 1473-1483
-
-
Paterson, H.M.1
Murphy, T.J.2
Purcell, E.J.3
-
65
-
-
28444464798
-
Mutations in TLR4 signaling that lead to increased susceptibility to infection in humans: an overview
-
Vogel S.N., Awomoyi A.A., Rallabhandi P., et al. Mutations in TLR4 signaling that lead to increased susceptibility to infection in humans: an overview. J Endotoxin Res 2005, 11:333-339.
-
(2005)
J Endotoxin Res
, vol.11
, pp. 333-339
-
-
Vogel, S.N.1
Awomoyi, A.A.2
Rallabhandi, P.3
-
66
-
-
0036227226
-
Mucosal and enterocyte IL-6 production during sepsis and endotoxemia-role of transcription factors and regulation by the stress response
-
Pritts T., Hungness E., Wang Q., et al. Mucosal and enterocyte IL-6 production during sepsis and endotoxemia-role of transcription factors and regulation by the stress response. Am J Surg 2002, 183:372-383.
-
(2002)
Am J Surg
, vol.183
, pp. 372-383
-
-
Pritts, T.1
Hungness, E.2
Wang, Q.3
-
67
-
-
0032997973
-
Cytokines and anticytokines in the pathogenesis of sepsis
-
ix
-
van der Poll T., van Deventer S.J. Cytokines and anticytokines in the pathogenesis of sepsis. Infect Dis Clin North Am 1999, 13:413-426. ix.
-
(1999)
Infect Dis Clin North Am
, vol.13
, pp. 413-426
-
-
van der Poll, T.1
van Deventer, S.J.2
-
68
-
-
0034064042
-
The inflammatory balance in human sepsis
-
Adrie C., Pinsky M.R. The inflammatory balance in human sepsis. Intensive Care Med 2000, 26:364-375.
-
(2000)
Intensive Care Med
, vol.26
, pp. 364-375
-
-
Adrie, C.1
Pinsky, M.R.2
-
69
-
-
1342270880
-
Pathogenesis of multiple organ dysfunction syndrome-endotoxin, inflammatory cells, and their mediators: cytokines and reactive oxygen species
-
Maier R.V. Pathogenesis of multiple organ dysfunction syndrome-endotoxin, inflammatory cells, and their mediators: cytokines and reactive oxygen species. Surg Infect(Larchmt) 2000, 1:197-205.
-
(2000)
Surg Infect(Larchmt)
, vol.1
, pp. 197-205
-
-
Maier, R.V.1
-
70
-
-
13244288781
-
The "cytokine profile": a code for sepsis
-
Ulloa L., Tracey K.J. The "cytokine profile": a code for sepsis. Trends Mol Med 2005, 11:56-63.
-
(2005)
Trends Mol Med
, vol.11
, pp. 56-63
-
-
Ulloa, L.1
Tracey, K.J.2
-
71
-
-
33746396118
-
What is new in cytokine research related to trauma/critical care
-
Jawa R.S., Kulaylat M.N., Baumann H., et al. What is new in cytokine research related to trauma/critical care. J Intensive Care Med 2006, 21:63-85.
-
(2006)
J Intensive Care Med
, vol.21
, pp. 63-85
-
-
Jawa, R.S.1
Kulaylat, M.N.2
Baumann, H.3
-
72
-
-
34247596961
-
Sepsis and multiple organ failure
-
Pinsky M.R. Sepsis and multiple organ failure. Contrib Nephrol 2007, 156:47-63.
-
(2007)
Contrib Nephrol
, vol.156
, pp. 47-63
-
-
Pinsky, M.R.1
-
73
-
-
77954558483
-
Novel insights for systemic inflammation in sepsis and hemorrhage
-
Cai B., Deitch E.A., Ulloa L. Novel insights for systemic inflammation in sepsis and hemorrhage. Mediators Inflamm 2010, 2010:642462.
-
(2010)
Mediators Inflamm
, vol.2010
, pp. 642462
-
-
Cai, B.1
Deitch, E.A.2
Ulloa, L.3
-
74
-
-
0037204948
-
TNF-R1 signaling: a beautiful pathway
-
Chen G., Goeddel D.V. TNF-R1 signaling: a beautiful pathway. Science 2002, 296:1634-1635.
-
(2002)
Science
, vol.296
, pp. 1634-1635
-
-
Chen, G.1
Goeddel, D.V.2
-
75
-
-
0037044575
-
The IkB-NFkB signaling module: temporal control and selective gene activation
-
Hoffmann A., Levchenko A., Scott M.L., et al. The IkB-NFkB signaling module: temporal control and selective gene activation. Science 2002, 298:1241-1245.
-
(2002)
Science
, vol.298
, pp. 1241-1245
-
-
Hoffmann, A.1
Levchenko, A.2
Scott, M.L.3
-
76
-
-
34548022149
-
Understanding the inflammatory cytokine response in pneumonia and sepsis: results of the Genetic and Inflammatory Markers of Sepsis (GenIMS) Study
-
Kellum J.A., Kong L., Fink M.P., et al. Understanding the inflammatory cytokine response in pneumonia and sepsis: results of the Genetic and Inflammatory Markers of Sepsis (GenIMS) Study. Arch Intern Med 2007, 167:1655-1663.
-
(2007)
Arch Intern Med
, vol.167
, pp. 1655-1663
-
-
Kellum, J.A.1
Kong, L.2
Fink, M.P.3
-
77
-
-
0028997703
-
Natural cytokine antagonists and endogenous antiendotoxin core antibodies in sepsis syndrome. The Sepsis Intervention Group
-
Goldie A.S., Fearon K.C., Ross J.A., et al. Natural cytokine antagonists and endogenous antiendotoxin core antibodies in sepsis syndrome. The Sepsis Intervention Group. JAMA 1995, 274:172-177.
-
(1995)
JAMA
, vol.274
, pp. 172-177
-
-
Goldie, A.S.1
Fearon, K.C.2
Ross, J.A.3
-
78
-
-
16944363557
-
Antiinflammatory cytokine responses during clinical sepsis and experimental endotoxemia: sequential measurements of plasma soluble interleukin (IL)-1 receptor type II, IL-10, and IL-13
-
van der Poll T., de Waal M.R., Coyle S.M., et al. Antiinflammatory cytokine responses during clinical sepsis and experimental endotoxemia: sequential measurements of plasma soluble interleukin (IL)-1 receptor type II, IL-10, and IL-13. J Infect Dis 1997, 175:118-122.
-
(1997)
J Infect Dis
, vol.175
, pp. 118-122
-
-
van der Poll, T.1
de Waal, M.R.2
Coyle, S.M.3
-
79
-
-
0032495658
-
Double-blind randomised controlled trial of monoclonal antibody to human tumour necrosis factor in treatment of septic shock. NORASEPT II Study Group
-
Abraham E., Anzueto A., Gutierrez G., et al. Double-blind randomised controlled trial of monoclonal antibody to human tumour necrosis factor in treatment of septic shock. NORASEPT II Study Group. Lancet 1998, 351:929-933.
-
(1998)
Lancet
, vol.351
, pp. 929-933
-
-
Abraham, E.1
Anzueto, A.2
Gutierrez, G.3
-
80
-
-
0035046049
-
Randomized, placebo-controlled trial of the anti-tumor necrosis factor antibody fragment afelimomab in hyperinflammatory response during severe sepsis: the RAMSES Study
-
Reinhart K., Menges T., Gardlund B., et al. Randomized, placebo-controlled trial of the anti-tumor necrosis factor antibody fragment afelimomab in hyperinflammatory response during severe sepsis: the RAMSES Study. Crit Care Med 2001, 29:765-769.
-
(2001)
Crit Care Med
, vol.29
, pp. 765-769
-
-
Reinhart, K.1
Menges, T.2
Gardlund, B.3
-
81
-
-
5644241698
-
Dysregulation of the immune response in severe sepsis
-
Pinsky M.R. Dysregulation of the immune response in severe sepsis. Am J Med Sci 2004, 328:220-229.
-
(2004)
Am J Med Sci
, vol.328
, pp. 220-229
-
-
Pinsky, M.R.1
-
83
-
-
34447530416
-
Stress molecules in sepsis and systemic inflammatory response syndrome
-
dib-Conquy M., Cavaillon J.M. Stress molecules in sepsis and systemic inflammatory response syndrome. FEBS Lett 2007, 581:3723-3733.
-
(2007)
FEBS Lett
, vol.581
, pp. 3723-3733
-
-
dib-Conquy, M.1
Cavaillon, J.M.2
-
84
-
-
0033538467
-
HMG-1 as a late mediator of endotoxin lethality in mice
-
Wang H., Bloom O., Zhang M., et al. HMG-1 as a late mediator of endotoxin lethality in mice. Science 1999, 285:248-251.
-
(1999)
Science
, vol.285
, pp. 248-251
-
-
Wang, H.1
Bloom, O.2
Zhang, M.3
-
85
-
-
20144380566
-
Persistent elevation of high mobility group box-1 protein (HMGB1) in patients with severe sepsis and septic shock
-
Sunden-Cullberg J., Norrby-Teglund A., Rouhiainen A., et al. Persistent elevation of high mobility group box-1 protein (HMGB1) in patients with severe sepsis and septic shock. Crit Care Med 2005, 33:564-573.
-
(2005)
Crit Care Med
, vol.33
, pp. 564-573
-
-
Sunden-Cullberg, J.1
Norrby-Teglund, A.2
Rouhiainen, A.3
-
86
-
-
34247128758
-
Circulating high-mobility group box 1 (HMGB1) concentrations are elevated in both uncomplicated pneumonia and pneumonia with severe sepsis
-
Angus D.C., Yang L., Kong L., et al. Circulating high-mobility group box 1 (HMGB1) concentrations are elevated in both uncomplicated pneumonia and pneumonia with severe sepsis. Crit Care Med 2007, 35:1061-1067.
-
(2007)
Crit Care Med
, vol.35
, pp. 1061-1067
-
-
Angus, D.C.1
Yang, L.2
Kong, L.3
-
87
-
-
9144241208
-
Reversing established sepsis with antagonists of endogenous high-mobility group box 1
-
Yang H., Ochani M., Li J., et al. Reversing established sepsis with antagonists of endogenous high-mobility group box 1. Proc Natl Acad Sci U S A 2004, 101:296-301.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 296-301
-
-
Yang, H.1
Ochani, M.2
Li, J.3
-
89
-
-
77950275298
-
Circulating mitochondrial DAMPs cause inflammatory responses to injury
-
Zhang Q., Raoof M., Chen Y., et al. Circulating mitochondrial DAMPs cause inflammatory responses to injury. Nature 2010, 464:104-107.
-
(2010)
Nature
, vol.464
, pp. 104-107
-
-
Zhang, Q.1
Raoof, M.2
Chen, Y.3
-
90
-
-
46749136744
-
Discovery and development of toll-like receptor 4 (TLR4) antagonists: a new paradigm for treating sepsis and other diseases
-
Leon C.G., Tory R., Jia J., et al. Discovery and development of toll-like receptor 4 (TLR4) antagonists: a new paradigm for treating sepsis and other diseases. PharmRes 2008, 25:1751-1761.
-
(2008)
PharmRes
, vol.25
, pp. 1751-1761
-
-
Leon, C.G.1
Tory, R.2
Jia, J.3
-
93
-
-
48149096398
-
HMGB1: endogenous danger signaling
-
Klune J.R., Dhupar R., Cardinal J., et al. HMGB1: endogenous danger signaling. Mol Med 2008, 14:476-484.
-
(2008)
Mol Med
, vol.14
, pp. 476-484
-
-
Klune, J.R.1
Dhupar, R.2
Cardinal, J.3
-
94
-
-
67650493786
-
Novel HMGB1-inhibiting therapeutic agents for experimental sepsis
-
Wang H., Ward M.F., Sama A.E. Novel HMGB1-inhibiting therapeutic agents for experimental sepsis. Shock 2009, 32:348-357.
-
(2009)
Shock
, vol.32
, pp. 348-357
-
-
Wang, H.1
Ward, M.F.2
Sama, A.E.3
-
95
-
-
74449089862
-
Targeting HMGB1 in inflammation
-
Yang H., Tracey K.J. Targeting HMGB1 in inflammation. Biochim Biophys Acta 2010, 1799:149-156.
-
(2010)
Biochim Biophys Acta
, vol.1799
, pp. 149-156
-
-
Yang, H.1
Tracey, K.J.2
-
96
-
-
0035226687
-
P38 MAP kinase: molecular target for the inhibition of pro-inflammatory cytokines
-
Adams J.L., Badger A.M., Kumar S., et al. p38 MAP kinase: molecular target for the inhibition of pro-inflammatory cytokines. Prog Med Chem 2001, 38:1-60.
-
(2001)
Prog Med Chem
, vol.38
, pp. 1-60
-
-
Adams, J.L.1
Badger, A.M.2
Kumar, S.3
-
97
-
-
33847188791
-
NF-kappaB inhibitors for the treatment of inflammatory diseases and cancer
-
Calzado M.A., Bacher S., Schmitz M.L. NF-kappaB inhibitors for the treatment of inflammatory diseases and cancer. Curr Med Chem 2007, 14:367-376.
-
(2007)
Curr Med Chem
, vol.14
, pp. 367-376
-
-
Calzado, M.A.1
Bacher, S.2
Schmitz, M.L.3
-
98
-
-
40949144895
-
Anti-inflammatory interventions of NF-kappaB signaling: potential applications and risks
-
Uwe S. Anti-inflammatory interventions of NF-kappaB signaling: potential applications and risks. Biochem Pharmacol 2008, 75:1567-1579.
-
(2008)
Biochem Pharmacol
, vol.75
, pp. 1567-1579
-
-
Uwe, S.1
-
99
-
-
75149172745
-
The acute inflammatory response in trauma/hemorrhage and traumatic brain injury: current state and emerging prospects
-
Namas R., Ghuma A., Hermus L., et al. The acute inflammatory response in trauma/hemorrhage and traumatic brain injury: current state and emerging prospects. Libyan J Med 2009, 4:136-148.
-
(2009)
Libyan J Med
, vol.4
, pp. 136-148
-
-
Namas, R.1
Ghuma, A.2
Hermus, L.3
-
101
-
-
77952163906
-
Translational systems approaches to the biology of inflammation and healing
-
Vodovotz Y., Constantine G., Faeder J., et al. Translational systems approaches to the biology of inflammation and healing. Immunopharmacol Immunotoxicol 2010, 32:181-195.
-
(2010)
Immunopharmacol Immunotoxicol
, vol.32
, pp. 181-195
-
-
Vodovotz, Y.1
Constantine, G.2
Faeder, J.3
-
102
-
-
0032778367
-
Inappropriate sympathetic activation at onset of septic shock: a spectral analysis approach
-
Annane D., Trabold F., Sharshar T., et al. Inappropriate sympathetic activation at onset of septic shock: a spectral analysis approach. Am J Respir Crit Care Med 1999, 160:458-465.
-
(1999)
Am J Respir Crit Care Med
, vol.160
, pp. 458-465
-
-
Annane, D.1
Trabold, F.2
Sharshar, T.3
-
103
-
-
0034948109
-
Cardiac variability in critically ill adults: influence of sepsis
-
Korach M., Sharshar T., Jarrin I., et al. Cardiac variability in critically ill adults: influence of sepsis. Crit Care Med 2001, 29:1380-1385.
-
(2001)
Crit Care Med
, vol.29
, pp. 1380-1385
-
-
Korach, M.1
Sharshar, T.2
Jarrin, I.3
-
104
-
-
0028943513
-
Autonomic control of the heart and peripheral vessels in human septic shock
-
Piepoli M., Garrard C.S., Kontoyannis D.A., et al. Autonomic control of the heart and peripheral vessels in human septic shock. Intensive Care Med 1995, 21:112-119.
-
(1995)
Intensive Care Med
, vol.21
, pp. 112-119
-
-
Piepoli, M.1
Garrard, C.S.2
Kontoyannis, D.A.3
-
106
-
-
0029988782
-
Heart rate variability. Standards of measurement, physiological interpretation, and clinical use. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology
-
Heart rate variability. Standards of measurement, physiological interpretation, and clinical use. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. Eur Heart J 1996, 17:354-381.
-
(1996)
Eur Heart J
, vol.17
, pp. 354-381
-
-
-
108
-
-
0021912061
-
Assessment of autonomic function in humans by heart rate spectral analysis
-
Pomeranz B., Macaulay R.J., Caudill M.A., et al. Assessment of autonomic function in humans by heart rate spectral analysis. Am J Physiol 1985, 248:H151-H153.
-
(1985)
Am J Physiol
, vol.248
-
-
Pomeranz, B.1
Macaulay, R.J.2
Caudill, M.A.3
-
109
-
-
0029979116
-
Experimental human endotoxemia increases cardiac regularity: results from a prospective, randomized, crossover trial
-
Godin P.J., Fleisher L.A., Eidsath A., et al. Experimental human endotoxemia increases cardiac regularity: results from a prospective, randomized, crossover trial. Crit Care Med 1996, 24:1117-1124.
-
(1996)
Crit Care Med
, vol.24
, pp. 1117-1124
-
-
Godin, P.J.1
Fleisher, L.A.2
Eidsath, A.3
-
110
-
-
0036301884
-
Heart rate variability in emergency department patients with sepsis
-
Barnaby D., Ferrick K., Kaplan D.T., et al. Heart rate variability in emergency department patients with sepsis. Acad Emerg Med 2002, 9:661-670.
-
(2002)
Acad Emerg Med
, vol.9
, pp. 661-670
-
-
Barnaby, D.1
Ferrick, K.2
Kaplan, D.T.3
-
111
-
-
34247145917
-
Characteristics of heart rate variability can predict impending septic shock in emergency department patients with sepsis
-
Chen W.L., Kuo C.D. Characteristics of heart rate variability can predict impending septic shock in emergency department patients with sepsis. Acad Emerg Med 2007, 14:392-397.
-
(2007)
Acad Emerg Med
, vol.14
, pp. 392-397
-
-
Chen, W.L.1
Kuo, C.D.2
-
112
-
-
0242609242
-
Heart rate variability as early marker of multiple organ dysfunction syndrome in septic patients
-
Pontet J., Contreras P., Curbelo A., et al. Heart rate variability as early marker of multiple organ dysfunction syndrome in septic patients. J Crit Care 2003, 18:156-163.
-
(2003)
J Crit Care
, vol.18
, pp. 156-163
-
-
Pontet, J.1
Contreras, P.2
Curbelo, A.3
-
113
-
-
69949162508
-
Continuous multi-parameter heart rate variability analysis heralds onset of sepsis in adults
-
Ahmad S., Ramsay T., Huebsch L., et al. Continuous multi-parameter heart rate variability analysis heralds onset of sepsis in adults. PLoS ONE 2009, 4:e6642.
-
(2009)
PLoS ONE
, vol.4
-
-
Ahmad, S.1
Ramsay, T.2
Huebsch, L.3
-
114
-
-
77449121950
-
Bench-to-bedside review: ventilatory abnormalities in sepsis
-
Magder S. Bench-to-bedside review: ventilatory abnormalities in sepsis. Crit Care 2009, 13:202.
-
(2009)
Crit Care
, vol.13
, pp. 202
-
-
Magder, S.1
-
115
-
-
0035880864
-
Effect of endotoxin on ventilation and breath variability: role of cyclooxygenase pathway
-
Preas H.L., Jubran A., Vandivier R.W., et al. Effect of endotoxin on ventilation and breath variability: role of cyclooxygenase pathway. Am J Respir Crit Care Med 2001, 164:620-626.
-
(2001)
Am J Respir Crit Care Med
, vol.164
, pp. 620-626
-
-
Preas, H.L.1
Jubran, A.2
Vandivier, R.W.3
-
116
-
-
67650609140
-
Heart-rate complexity for prediction of prehospital lifesaving interventions in trauma patients
-
Cancio L.C., Batchinsky A.I., Salinas J., et al. Heart-rate complexity for prediction of prehospital lifesaving interventions in trauma patients. J Trauma 2008, 65:813-819.
-
(2008)
J Trauma
, vol.65
, pp. 813-819
-
-
Cancio, L.C.1
Batchinsky, A.I.2
Salinas, J.3
-
117
-
-
0029784526
-
Why sepsis trials fail
-
Bone R.C. Why sepsis trials fail. JAMA 1996, 276:565-566.
-
(1996)
JAMA
, vol.276
, pp. 565-566
-
-
Bone, R.C.1
-
118
-
-
0033866133
-
Multiple organ dysfunction syndrome: exploring the paradigm of complex nonlinear systems
-
Seely A.J., Christou N.V. Multiple organ dysfunction syndrome: exploring the paradigm of complex nonlinear systems. Crit Care Med 2000, 28:2193-2200.
-
(2000)
Crit Care Med
, vol.28
, pp. 2193-2200
-
-
Seely, A.J.1
Christou, N.V.2
-
119
-
-
33947181077
-
Deciphering the complexity of acute inflammation using mathematical models
-
Vodovotz Y. Deciphering the complexity of acute inflammation using mathematical models. Immunol Res 2006, 36:237-245.
-
(2006)
Immunol Res
, vol.36
, pp. 237-245
-
-
Vodovotz, Y.1
-
120
-
-
5644230749
-
Through a glass darkly: the brave new world of in silico modeling
-
Marshall J.C. Through a glass darkly: the brave new world of in silico modeling. Crit Care Med 2004, 32:2157-2159.
-
(2004)
Crit Care Med
, vol.32
, pp. 2157-2159
-
-
Marshall, J.C.1
-
121
-
-
33947193958
-
Evidence-based modeling of critical illness: an initial consensus from the Society for Complexity in Acute Illness
-
Vodovotz Y., Clermont G., Hunt C.A., et al. Evidence-based modeling of critical illness: an initial consensus from the Society for Complexity in Acute Illness. J Crit Care 2007, 22:77-84.
-
(2007)
J Crit Care
, vol.22
, pp. 77-84
-
-
Vodovotz, Y.1
Clermont, G.2
Hunt, C.A.3
-
123
-
-
0034677755
-
Mechanism-based target identification and drug discovery in cancer research
-
Gibbs J.B. Mechanism-based target identification and drug discovery in cancer research. Science 2000, 287:1969-1973.
-
(2000)
Science
, vol.287
, pp. 1969-1973
-
-
Gibbs, J.B.1
-
124
-
-
0037378771
-
Investigation of early events in Fc epsilon RI-mediated signaling using a detailed mathematical model
-
Faeder J.R., Hlavacek W.S., Reischl I., et al. Investigation of early events in Fc epsilon RI-mediated signaling using a detailed mathematical model. J Immunol 2003, 170:3769-3781.
-
(2003)
J Immunol
, vol.170
, pp. 3769-3781
-
-
Faeder, J.R.1
Hlavacek, W.S.2
Reischl, I.3
-
125
-
-
57749186048
-
A simple mathematical model of signaling resulting from the binding of lipopolysaccharide with Toll-like receptor 4 demonstrates inherent preconditioning behavior
-
Rivišre B., Epshteyn Y., Swigon D., et al. A simple mathematical model of signaling resulting from the binding of lipopolysaccharide with Toll-like receptor 4 demonstrates inherent preconditioning behavior. Math Biosci 2009, 217:19-26.
-
(2009)
Math Biosci
, vol.217
, pp. 19-26
-
-
Rivišre, B.1
Epshteyn, Y.2
Swigon, D.3
-
126
-
-
21744440089
-
The acute inflammatory response in diverse shock states
-
Chow C.C., Clermont G., Kumar R., et al. The acute inflammatory response in diverse shock states. Shock 2005, 24:74-84.
-
(2005)
Shock
, vol.24
, pp. 74-84
-
-
Chow, C.C.1
Clermont, G.2
Kumar, R.3
-
127
-
-
33747106908
-
A reduced mathematical model of the acute inflammatory response: I. Derivation of model and analysis of anti-inflammation
-
Reynolds A., Rubin J., Clermont G., et al. A reduced mathematical model of the acute inflammatory response: I. Derivation of model and analysis of anti-inflammation. J Theor Biol 2006, 242:220-236.
-
(2006)
J Theor Biol
, vol.242
, pp. 220-236
-
-
Reynolds, A.1
Rubin, J.2
Clermont, G.3
-
128
-
-
33747094446
-
A reduced mathematical model of the acute inflammatory response: II. Capturing scenarios of repeated endotoxin administration
-
Day J., Rubin J., Vodovotz Y., et al. A reduced mathematical model of the acute inflammatory response: II. Capturing scenarios of repeated endotoxin administration. J Theor Biol 2006, 242:237-256.
-
(2006)
J Theor Biol
, vol.242
, pp. 237-256
-
-
Day, J.1
Rubin, J.2
Vodovotz, Y.3
-
129
-
-
67749139592
-
Mathematical modeling of post-hemorrhage inflammation in mice: studies using a novel, computer-controlled, closed-loop hemorrhage apparatus
-
Torres A., Bentley T., Bartels J., et al. Mathematical modeling of post-hemorrhage inflammation in mice: studies using a novel, computer-controlled, closed-loop hemorrhage apparatus. Shock 2009, 32:172-178.
-
(2009)
Shock
, vol.32
, pp. 172-178
-
-
Torres, A.1
Bentley, T.2
Bartels, J.3
-
130
-
-
57849104348
-
Modeling endotoxin-induced systemic inflammation using an indirect response approach
-
Foteinou P.T., Calvano S.E., Lowry S.F., et al. Modeling endotoxin-induced systemic inflammation using an indirect response approach. Math Biosci 2009, 217:27-42.
-
(2009)
Math Biosci
, vol.217
, pp. 27-42
-
-
Foteinou, P.T.1
Calvano, S.E.2
Lowry, S.F.3
-
131
-
-
62849112761
-
In silico simulation of corticosteroids effect on an NFkB- dependent physicochemical model of systemic inflammation
-
Foteinou P.T., Calvano S.E., Lowry S.F., et al. In silico simulation of corticosteroids effect on an NFkB- dependent physicochemical model of systemic inflammation. PLoS ONE 2009, 4:e4706.
-
(2009)
PLoS ONE
, vol.4
-
-
Foteinou, P.T.1
Calvano, S.E.2
Lowry, S.F.3
-
132
-
-
37549004342
-
A mathematical simulation of the inflammatory response to anthrax infection
-
Kumar R., Chow C.C., Bartels J., et al. A mathematical simulation of the inflammatory response to anthrax infection. Shock 2008, 29:104-111.
-
(2008)
Shock
, vol.29
, pp. 104-111
-
-
Kumar, R.1
Chow, C.C.2
Bartels, J.3
-
133
-
-
77956321525
-
Using a mathematical model to analyze the role of probiotics and inflammation in necrotizing enterocolitis
-
Arciero J., Rubin J., Upperman J., et al. Using a mathematical model to analyze the role of probiotics and inflammation in necrotizing enterocolitis. PLoS ONE 2010, 5:e10066.
-
(2010)
PLoS ONE
, vol.5
-
-
Arciero, J.1
Rubin, J.2
Upperman, J.3
-
134
-
-
33749022785
-
In silico and in vivo approach to elucidate the inflammatory complexity of CD14-deficient mice
-
Prince J.M., Levy R.M., Bartels J., et al. In silico and in vivo approach to elucidate the inflammatory complexity of CD14-deficient mice. Mol Med 2006, 12:88-96.
-
(2006)
Mol Med
, vol.12
, pp. 88-96
-
-
Prince, J.M.1
Levy, R.M.2
Bartels, J.3
-
135
-
-
33751222859
-
The role of initial trauma in the host's response to injury and hemorrhage: Insights from a comparison of mathematical simulations and hepatic transcriptomic analysis
-
Lagoa C.E., Bartels J., Baratt A., et al. The role of initial trauma in the host's response to injury and hemorrhage: Insights from a comparison of mathematical simulations and hepatic transcriptomic analysis. Shock 2006, 26:592-600.
-
(2006)
Shock
, vol.26
, pp. 592-600
-
-
Lagoa, C.E.1
Bartels, J.2
Baratt, A.3
-
136
-
-
47849114337
-
An ensemble of models of the acute inflammatory response to bacterial lipopolysaccharide in rats: results from parameter space reduction
-
Daun S., Rubin J., Vodovotz Y., et al. An ensemble of models of the acute inflammatory response to bacterial lipopolysaccharide in rats: results from parameter space reduction. J Theor Biol 2008, 253:843-853.
-
(2008)
J Theor Biol
, vol.253
, pp. 843-853
-
-
Daun, S.1
Rubin, J.2
Vodovotz, Y.3
-
137
-
-
77953214777
-
Multiscale model for the assessment of autonomic dysfunction in human endotoxemia
-
Foteinou P.T., Calvano S.E., Lowry S.F., et al. Multiscale model for the assessment of autonomic dysfunction in human endotoxemia. Physiol Genomics 2010, 42:5-19.
-
(2010)
Physiol Genomics
, vol.42
, pp. 5-19
-
-
Foteinou, P.T.1
Calvano, S.E.2
Lowry, S.F.3
-
138
-
-
4043056616
-
In silico design of clinical trials: a method coming of age
-
Clermont G., Bartels J., Kumar R., et al. In silico design of clinical trials: a method coming of age. Crit Care Med 2004, 32:2061-2070.
-
(2004)
Crit Care Med
, vol.32
, pp. 2061-2070
-
-
Clermont, G.1
Bartels, J.2
Kumar, R.3
-
139
-
-
79953894415
-
In silico augmentation of the drug development pipeline: examples from the study of acute inflammation
-
An G., Bartels J., Vodovotz Y. In silico augmentation of the drug development pipeline: examples from the study of acute inflammation. Drug Dev Res 2010, 72:1-14.
-
(2010)
Drug Dev Res
, vol.72
, pp. 1-14
-
-
An, G.1
Bartels, J.2
Vodovotz, Y.3
-
140
-
-
52449098209
-
Human endotoxemia as a model of systemic inflammation
-
Andreasen A.S., Krabbe K.S., Krogh-Madsen R., et al. Human endotoxemia as a model of systemic inflammation. Curr Med Chem 2008, 15:1697-1705.
-
(2008)
Curr Med Chem
, vol.15
, pp. 1697-1705
-
-
Andreasen, A.S.1
Krabbe, K.S.2
Krogh-Madsen, R.3
-
141
-
-
79952163506
-
A physiological model for autonomic heart rate regulation in human endotoxemia
-
(in press)
-
Foteinou P.T., Calvano S.E., Lowry S.F., et al. A physiological model for autonomic heart rate regulation in human endotoxemia. Shock 2011, (in press).
-
(2011)
Shock
-
-
Foteinou, P.T.1
Calvano, S.E.2
Lowry, S.F.3
-
142
-
-
74549170381
-
Translational systems biology of inflammation and healing
-
Vodovotz Y. Translational systems biology of inflammation and healing. Wound Repair Regen 2010, 18:3-7.
-
(2010)
Wound Repair Regen
, vol.18
, pp. 3-7
-
-
Vodovotz, Y.1
-
143
-
-
5644258227
-
In vivo, in vitro, in silico
-
Buchman T.G. In vivo, in vitro, in silico. Crit Care Med 2004, 32:2159-2160.
-
(2004)
Crit Care Med
, vol.32
, pp. 2159-2160
-
-
Buchman, T.G.1
-
144
-
-
33746713672
-
Management of severe sepsis and septic shock: challenges and recommendations
-
ix
-
Gullo A., Bianco N., Berlot G. Management of severe sepsis and septic shock: challenges and recommendations. Crit Care Clin 2006, 22:489-501. ix.
-
(2006)
Crit Care Clin
, vol.22
, pp. 489-501
-
-
Gullo, A.1
Bianco, N.2
Berlot, G.3
-
145
-
-
0037709770
-
C-reactive protein levels correlate with mortality and organ failure in critically ill patients
-
Lobo S.M., Lobo F.R., Bota D.P., et al. C-reactive protein levels correlate with mortality and organ failure in critically ill patients. Chest 2003, 123:2043-2049.
-
(2003)
Chest
, vol.123
, pp. 2043-2049
-
-
Lobo, S.M.1
Lobo, F.R.2
Bota, D.P.3
-
146
-
-
0000769626
-
Procalcitonin used as a marker of infection in the intensive care unit
-
Ugarte H., Silva E., Mercan D., et al. Procalcitonin used as a marker of infection in the intensive care unit. Crit Care Med 1999, 27:498-504.
-
(1999)
Crit Care Med
, vol.27
, pp. 498-504
-
-
Ugarte, H.1
Silva, E.2
Mercan, D.3
-
147
-
-
0027731546
-
Plasma cytokine and endotoxin levels correlate with survival in patients with the sepsis syndrome
-
Casey L.C., Balk R.A., Bone R.C. Plasma cytokine and endotoxin levels correlate with survival in patients with the sepsis syndrome. Ann Intern Med 1993, 119:771-778.
-
(1993)
Ann Intern Med
, vol.119
, pp. 771-778
-
-
Casey, L.C.1
Balk, R.A.2
Bone, R.C.3
-
148
-
-
0026575846
-
Cytokine serum level during severe sepsis in human IL-6 as a marker of severity
-
Damas P., Ledoux D., Nys M., et al. Cytokine serum level during severe sepsis in human IL-6 as a marker of severity. Ann Surg 1992, 215:356-362.
-
(1992)
Ann Surg
, vol.215
, pp. 356-362
-
-
Damas, P.1
Ledoux, D.2
Nys, M.3
-
149
-
-
0031445867
-
Blood interleukin 10 levels parallel the severity of septic shock
-
Friedman G., Jankowski S., Marchant A., et al. Blood interleukin 10 levels parallel the severity of septic shock. J Crit Care 1997, 12:183-187.
-
(1997)
J Crit Care
, vol.12
, pp. 183-187
-
-
Friedman, G.1
Jankowski, S.2
Marchant, A.3
-
150
-
-
0027457502
-
Serum cytokine levels in human septic shock. Relation to multiple-system organ failure and mortality
-
Pinsky M.R., Vincent J.L., Deviere J., et al. Serum cytokine levels in human septic shock. Relation to multiple-system organ failure and mortality. Chest 1993, 103:565-575.
-
(1993)
Chest
, vol.103
, pp. 565-575
-
-
Pinsky, M.R.1
Vincent, J.L.2
Deviere, J.3
-
151
-
-
3042785468
-
Diagnostic and prognostic implications of endotoxemia in critical illness: results of the MEDIC study
-
Marshall J.C., Foster D., Vincent J.L., et al. Diagnostic and prognostic implications of endotoxemia in critical illness: results of the MEDIC study. J Infect Dis 2004, 190:527-534.
-
(2004)
J Infect Dis
, vol.190
, pp. 527-534
-
-
Marshall, J.C.1
Foster, D.2
Vincent, J.L.3
-
152
-
-
3042818432
-
Plasma level of a triggering receptor expressed on myeloid cells-1: its diagnostic accuracy in patients with suspected sepsis
-
Gibot S., Kolopp-Sarda M.N., Bene M.C., et al. Plasma level of a triggering receptor expressed on myeloid cells-1: its diagnostic accuracy in patients with suspected sepsis. Ann Intern Med 2004, 141:9-15.
-
(2004)
Ann Intern Med
, vol.141
, pp. 9-15
-
-
Gibot, S.1
Kolopp-Sarda, M.N.2
Bene, M.C.3
-
153
-
-
1242342711
-
Utility of activated partial thromboplastin time waveform analysis for identification of sepsis and overt disseminated intravascular coagulation in patients admitted to a surgical intensive care unit
-
Dempfle C.E., Lorenz S., Smolinski M., et al. Utility of activated partial thromboplastin time waveform analysis for identification of sepsis and overt disseminated intravascular coagulation in patients admitted to a surgical intensive care unit. Crit Care Med 2004, 32:520-524.
-
(2004)
Crit Care Med
, vol.32
, pp. 520-524
-
-
Dempfle, C.E.1
Lorenz, S.2
Smolinski, M.3
-
154
-
-
12244255748
-
Early identification of sepsis and mortality risks through simple, rapid clot-waveform analysis. Implications of lipoprotein-complexed C reactive protein formation
-
Toh C.H., Ticknor L.O., Downey C., et al. Early identification of sepsis and mortality risks through simple, rapid clot-waveform analysis. Implications of lipoprotein-complexed C reactive protein formation. Intensive Care Med 2003, 29:55-61.
-
(2003)
Intensive Care Med
, vol.29
, pp. 55-61
-
-
Toh, C.H.1
Ticknor, L.O.2
Downey, C.3
-
155
-
-
0033866133
-
Multiple organ dysfunction syndrome: exploring the paradigm of complex nonlinear systems
-
[Review]
-
Seely A.J.E., Christou N.V. Multiple organ dysfunction syndrome: exploring the paradigm of complex nonlinear systems. Crit Care Med 2000, 28:2193-2200. [Review].
-
(2000)
Crit Care Med
, vol.28
, pp. 2193-2200
-
-
Seely, A.J.E.1
Christou, N.V.2
-
157
-
-
30444431610
-
Heart rate characteristics monitoring for neonatal sepsis
-
Moorman J.R., Lake D.E., Griffin M.P. Heart rate characteristics monitoring for neonatal sepsis. IEEE Trans Biomed Eng 2006, 53:126-132.
-
(2006)
IEEE Trans Biomed Eng
, vol.53
, pp. 126-132
-
-
Moorman, J.R.1
Lake, D.E.2
Griffin, M.P.3
-
158
-
-
65249101633
-
Impaired regulation of cardiac function in sepsis, SIRS, and MODS
-
Werdan K., Schmidt H., Ebelt H., et al. Impaired regulation of cardiac function in sepsis, SIRS, and MODS. Can J Physiol Pharmacol 2009, 87:266-274.
-
(2009)
Can J Physiol Pharmacol
, vol.87
, pp. 266-274
-
-
Werdan, K.1
Schmidt, H.2
Ebelt, H.3
|