Fuzzy Logic Analysis of Kinase Pathway Crosstalk in TNF/EGF/Insulin-Induced Signaling

PLoS Computational Biology

Volumn 5, Issue 4, 2009, Pages

  Aldridge, Bree B ^a,b,c,d   Saez Rodriguez, Julio ^a,b,c   Muhlich, Jeremy L ^a,c   Sorger, Peter K ^a,b,c   Lauffenburger, Douglas A ^a,b,c  

^a Center for Cell Decision Processes   (United States)

^b Massachusetts Institute of Technology Cambridge   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SIGNALING; COMPUTER CIRCUITS; FUZZY LOGIC; SIGNALING;

CELLS SIGNALING; COLON CARCINOMA CELLS; DOWN-REGULATION; DOWN-STREAM; FUZZY LOGIC ANALYSIS; FUZZY-LOGIC; HUMAN COLON; INSULIN RECEPTORS; MECHANISTICS; SIGNALING NETWORKS;

CROSSTALK;

EPIDERMAL GROWTH FACTOR; I KAPPA B KINASE; INSULIN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; TUMOR NECROSIS FACTOR; PHOSPHOTRANSFERASE; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; AUTOCRINE EFFECT; CARCINOMA CELL; CELL COMMUNICATION; COLON CARCINOMA; CYTOLOGY; DOWN REGULATION; ENZYME INHIBITION; FUZZY LOGIC; HUMAN; HUMAN CELL; MOLECULAR MODEL; PREDICTION; QUANTITATIVE ANALYSIS; REGULATORY MECHANISM; SIMULATION; SURVIVAL; BIOLOGICAL MODEL; COLON TUMOR; COMPUTER SIMULATION; METABOLISM; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

CELL LINE, TUMOR; COLONIC NEOPLASMS; COMPUTER SIMULATION; EPIDERMAL GROWTH FACTOR; FUZZY LOGIC; HUMANS; MODELS, BIOLOGICAL; PHOSPHOTRANSFERASES; RECEPTOR, INSULIN; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 65349179556     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1000340     Document Type: Article

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