A two-compartment mathematical model of endotoxin-induced inflammatory and physiologic alterations in swine

Critical Care Medicine

Volumn 40, Issue 4, 2012, Pages 1052-1063

  Nieman, Gary ^a   Brown, David ^a,b   Sarkar, Joydeep ^b   Kubiak, Brian ^a   Ziraldo, Cordelia ^c   Dutta Moscato, Joyeeta ^c   Vieau, Christopher ^a   Barclay, Derek ^c   Gatto, Louis ^d   Maier, Kristopher ^a   Constantine, Gregory ^c   Billiar, Timothy R ^c   Zamora, Ruben ^c   Mi, Qi ^c   Chang, Steve ^b   Vodovotz, Yoram ^c  

^a State University of New York Upstate Medical University: College of Medicine   (United States)

^b Department of Immunetrics ^*  (United States)

^c UNIVERSITY OF PITTSBURGH   (United States)

^d STATE UNIVERSITY OF NEW YORK   (United States)

Author keywords

endotoxemia; inflammation; models; sepsis; swine; systems biology; theoretical

Indexed keywords

ENDOTOXIN; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 4; INTERLEUKIN 6; INTERLEUKIN 8; OXYGEN; TUMOR NECROSIS FACTOR ALPHA;

ACUTE LUNG INJURY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ARTIFICIAL VENTILATION; AUTOPSY; BLOOD PRESSURE; BLOOD SAMPLING; CELL MIGRATION; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE SEVERITY; ENDOTOXEMIA; FEMALE; INFLAMMATION; MATHEMATICAL MODEL; NONHUMAN; OUTCOME ASSESSMENT; PHENOTYPE; PREDICTION; PRIORITY JOURNAL; SEPSIS; SWINE; TRACHEOSTOMY;

ACUTE LUNG INJURY; ANIMALS; ENDOTOXEMIA; ENDOTOXINS; FEMALE; HEMODYNAMICS; HMGB1 PROTEIN; INFLAMMATION; INTERLEUKIN-10; INTERLEUKIN-1BETA; INTERLEUKIN-4; INTERLEUKIN-6; INTERLEUKIN-8; MODELS, BIOLOGICAL; PRINCIPAL COMPONENT ANALYSIS; RESPIRATORY PHYSIOLOGICAL PHENOMENA; SWINE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84863338100     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e31823e986a     Document Type: Article

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