A domain-oriented approach to the reduction of combinatorial complexity in signal transduction networks

BMC Bioinformatics

Volumn 7, Issue , 2006, Pages

  Conzelmann, Holger ^a   Saez Rodriguez, Julio ^b   Sauter, Thomas ^a   Kholodenko, Boris N ^c   Gilles, Ernst D ^a,b  

^a UNIVERSITY OF STUTTGART   (Germany)

^b MAX PLANCK INSTITUTE FOR DYNAMICS OF COMPLEX TECHNICAL SYSTEMS   (Germany)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMBINATORIAL COMPLEXITY; COMBINATORIAL EXPLOSION; DOMAIN INTERACTIONS; MACROSCOPIC QUANTITIES; MULTI-PROTEIN COMPLEX; MULTIDOMAIN PROTEINS; SIGNAL TRANSDUCTION NETWORKS; SIGNALING NETWORKS;

MODEL STRUCTURES; PROTEINS; SIGNAL TRANSDUCTION; SIGNALING;

COMPLEX NETWORKS;

SCAFFOLD PROTEIN; CELL SURFACE RECEPTOR; PROTEIN BINDING;

ARTICLE; COMPLEX FORMATION; MATHEMATICAL MODEL; MOLECULAR DYNAMICS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN INTERACTION; SIGNAL TRANSDUCTION; SIMULATION; T LYMPHOCYTE ACTIVATION; BINDING SITE; BIOLOGICAL MODEL; CHEMICAL MODEL; CHEMISTRY; COMBINATORIAL CHEMISTRY; COMPUTER SIMULATION; EVALUATION STUDY; METABOLISM; PHYSIOLOGY; PROCEDURES; PROTEIN ANALYSIS; STRUCTURE ACTIVITY RELATION;

BINDING SITES; COMBINATORIAL CHEMISTRY TECHNIQUES; COMPUTER SIMULATION; MODELS, BIOLOGICAL; MODELS, CHEMICAL; PROTEIN BINDING; PROTEIN INTERACTION MAPPING; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33645238574     PISSN: 14712105     EISSN: 14712105     Source Type: Journal    
DOI: 10.1186/1471-2105-7-34     Document Type: Article

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