Input-output behavior of ErbB signaling pathways as revealed by a mass action model trained against dynamic data

Molecular Systems Biology

Volumn 5, Issue , 2009, Pages

  Chen, William W ^a   Schoeberl, Birgit ^b   Jasper, Paul J ^a   Niepel, Mario ^a   Nielsen, Ulrik B ^b   Lauffenburger, Douglas A ^c   Sorger, Peter K ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MERRIMACK PHARMACEUTICALS   (United States)

^c Massachusetts Institute of Technology Cambridge   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR 3; EPIDERMAL GROWTH FACTOR RECEPTOR 4; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN SH2; ONCOPROTEIN;

ARTICLE; ENZYME ACTIVITY; MATHEMATICAL MODEL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SENSITIVITY ANALYSIS; SIGNAL TRANSDUCTION; KINETICS; METABOLISM; SENSITIVITY AND SPECIFICITY;

KINETICS; MAP KINASE SIGNALING SYSTEM; ONCOGENE PROTEINS V-ERBB; SENSITIVITY AND SPECIFICITY; SIGNAL TRANSDUCTION;

EID: 58549083142     PISSN: 17444292     EISSN: 17444292     Source Type: Journal    
DOI: 10.1038/msb.2008.74     Document Type: Article

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