-
1
-
-
0022499547
-
Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin
-
Hirano T et al (1986) Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin. Nature 324: 73-76
-
(1986)
Nature
, vol.324
, pp. 73-76
-
-
Hirano, T.1
-
2
-
-
0025102756
-
Haemopoietic receptors and helical cytokines
-
Bazan JF (1990) Haemopoietic receptors and helical cytokines. Immunol Today 11: 350-354
-
(1990)
Immunol Today
, vol.11
, pp. 350-354
-
-
Bazan, J.F.1
-
3
-
-
0023685762
-
Cloning and expression of the human interleukin-6 (BSF-2/IFN beta 2) receptor
-
Yamasaki K et al (1988) Cloning and expression of the human interleukin-6 (BSF-2/IFN beta 2) receptor. Science 241: 825-828
-
(1988)
Science
, vol.241
, pp. 825-828
-
-
Yamasaki, K.1
-
4
-
-
0025630163
-
Molecular cloning and expression of an IL-6 signal transducer, gp130
-
Hibi M et al (1990) Molecular cloning and expression of an IL-6 signal transducer, gp130. Cell 63: 1149-1157
-
(1990)
Cell
, vol.63
, pp. 1149-1157
-
-
Hibi, M.1
-
5
-
-
0041677606
-
Principles of interleukin (IL)-6-type cytokine signalling and its regulation
-
Heinrich PC et al (2003) Principles of interleukin (IL)-6-type cytokine signalling and its regulation. Biochem J 374: 1-20
-
(2003)
Biochem J
, vol.374
, pp. 1-20
-
-
Heinrich, P.C.1
-
6
-
-
33747245173
-
Updating IL-6 classicand trans-signaling
-
Scheller J et al (2006) Updating IL-6 classicand trans-signaling. Signal Transduct 6: 240-259
-
(2006)
Signal Transduct
, vol.6
, pp. 240-259
-
-
Scheller, J.1
-
7
-
-
33748848714
-
Interleukin-6 biology is coordinated by membrane-bound and soluble receptors: Role in inflammation and cancer
-
Rose-John S et al (2006) Interleukin-6 biology is coordinated by membrane-bound and soluble receptors: role in inflammation and cancer. J Leukoc Biol 80: 227-236
-
(2006)
J Leukoc Biol
, vol.80
, pp. 227-236
-
-
Rose-John, S.1
-
8
-
-
80052358980
-
Therapeutic strategies for the clinical blockade of IL-6/gp130 signaling
-
Jones S et al (2011) Therapeutic strategies for the clinical blockade of IL-6/gp130 signaling. J Clin Invest 121: 3375-3383
-
(2011)
J Clin Invest
, vol.121
, pp. 3375-3383
-
-
Jones, S.1
-
9
-
-
33748979339
-
Multilevel regulation of IL-6R by IL-6-sIL-6R fusion protein according to the primitiveness of peripheral blood-derived CD133+ cells
-
Campard D et al (2006) Multilevel regulation of IL-6R by IL-6-sIL-6R fusion protein according to the primitiveness of peripheral blood-derived CD133+ cells. Stem Cells 24: 1302-1314
-
(2006)
Stem Cells
, vol.24
, pp. 1302-1314
-
-
Campard, D.1
-
10
-
-
0028226196
-
Soluble receptors for cytokines and growth factors: Generation and biological function
-
Rose-John S, Heinrich PC (1994) Soluble receptors for cytokines and growth factors: generation and biological function. Biochem J 300(Pt 2): 281-290
-
(1994)
Biochem J
, vol.300
, Issue.PART 2
, pp. 281-290
-
-
Rose-John, S.1
Heinrich, P.C.2
-
11
-
-
0030891228
-
Role of IL-6 and its soluble receptor in induction of chemokines and leukocyte recruitment
-
Romano M et al (1997) Role of IL-6 and its soluble receptor in induction of chemokines and leukocyte recruitment. Immunity 6: 315-325
-
(1997)
Immunity
, vol.6
, pp. 315-325
-
-
Romano, M.1
-
12
-
-
0027398766
-
The soluble interleukin- 6 receptor is generated by shedding
-
Müllberg J et al (1993) The soluble interleukin- 6 receptor is generated by shedding. Eur J Immunol 23: 473-480
-
(1993)
Eur J Immunol
, vol.23
, pp. 473-480
-
-
Müllberg, J.1
-
13
-
-
0027074343
-
Protein kinase C activity is rate limiting for shedding of the interleukin-6 receptor
-
Müllberg J et al (1992) Protein kinase C activity is rate limiting for shedding of the interleukin-6 receptor. Biochem Biophys Res Commun 189: 794-800
-
(1992)
Biochem Biophys Res Commun
, vol.189
, pp. 794-800
-
-
Müllberg, J.1
-
14
-
-
33845668702
-
Sleep enhances IL-6 trans-signaling in humans
-
Dimitrov S et al (2006) Sleep enhances IL-6 trans-signaling in humans. FASEB J 20(12): 2174-2176
-
(2006)
FASEB J
, vol.20
, Issue.12
, pp. 2174-2176
-
-
Dimitrov, S.1
-
15
-
-
79960923986
-
ADAM17: A molecular switch to control inflammation and tissue regeneration
-
Scheller J et al (2011) ADAM17: a molecular switch to control inflammation and tissue regeneration. Trends Immunol 32: 380-387
-
(2011)
Trends Immunol
, vol.32
, pp. 380-387
-
-
Scheller, J.1
-
16
-
-
0035253242
-
Recognition sequences and structural elements contribute to shedding susceptibility of membrane proteins
-
Althoff K et al (2001) Recognition sequences and structural elements contribute to shedding susceptibility of membrane proteins. Biochem J 353: 663-672
-
(2001)
Biochem J
, vol.353
, pp. 663-672
-
-
Althoff, K.1
-
17
-
-
0034026325
-
Shedding of interleukin- 6 receptor and tumor necrosis factor alpha. Contribution of the stalk sequence to the cleavage pattern of transmembrane proteins
-
Althoff K et al (2000) Shedding of interleukin- 6 receptor and tumor necrosis factor alpha. Contribution of the stalk sequence to the cleavage pattern of transmembrane proteins. Eur J Biochem 267: 2624-2631
-
(2000)
Eur J Biochem
, vol.267
, pp. 2624-2631
-
-
Althoff, K.1
-
18
-
-
0141866756
-
Cellular cholesterol depletion triggers shedding of the human interleukin-6 receptor by ADAM10 and ADAM17 (TACE)
-
Matthews V et al (2003) Cellular cholesterol depletion triggers shedding of the human interleukin-6 receptor by ADAM10 and ADAM17 (TACE). J Biol Chem 278: 38829-38839
-
(2003)
J Biol Chem
, vol.278
, pp. 38829-38839
-
-
Matthews, V.1
-
19
-
-
0028799113
-
A metalloprotease inhibitor blocks shedding of the IL-6 receptor and the p60 TNF receptor
-
Mullberg J et al (1995) A metalloprotease inhibitor blocks shedding of the IL-6 receptor and the p60 TNF receptor. J Immunol 155: 5198-5205
-
(1995)
J Immunol
, vol.155
, pp. 5198-5205
-
-
Mullberg, J.1
-
20
-
-
8044257704
-
A metalloproteinase disintegrin that releases tumour-necrosis factor- alpha from cells
-
Black RA et al (1997) A metalloproteinase disintegrin that releases tumour-necrosis factor- alpha from cells. Nature 385: 729-733
-
(1997)
Nature
, vol.385
, pp. 729-733
-
-
Black, R.A.1
-
21
-
-
8044250278
-
Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-alpha
-
Moss ML et al (1997) Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-alpha. Nature 385: 733-736
-
(1997)
Nature
, vol.385
, pp. 733-736
-
-
Moss, M.L.1
-
22
-
-
33947500486
-
Cytokines are a therapeutic target for the prevention of inflammation-induced cancers
-
Rose-John S, Schooltink H (2007) Cytokines are a therapeutic target for the prevention of inflammation-induced cancers. Recent Results Cancer Res 174: 57-66
-
(2007)
Recent Results Cancer Res
, vol.174
, pp. 57-66
-
-
Rose-John, S.1
Schooltink, H.2
-
23
-
-
0038642195
-
IL-6 type cytokine receptor complexes: Hexamer
-
Grotzinger J et al (1999) IL-6 type cytokine receptor complexes: hexamer, tetramer or both? Biol Chem 380: 803-813
-
(1999)
Tetramer or Both? Biol Chem
, vol.380
, pp. 803-813
-
-
Grotzinger, J.1
-
24
-
-
0037987019
-
The family of the IL-6-type cytokines: Specificity and promiscuity of the receptor complexes
-
Grotzinger J et al (1997) The family of the IL-6-type cytokines: specificity and promiscuity of the receptor complexes. Proteins 27: 96-109
-
(1997)
Proteins
, vol.27
, pp. 96-109
-
-
Grotzinger, J.1
-
25
-
-
0030614539
-
I. A bioactive designer cytokine for human hematopoietic progenitor cell expansion
-
Fischer M et al (1997) I. A bioactive designer cytokine for human hematopoietic progenitor cell expansion. Nat Biotechnol 15: 142-145
-
(1997)
Nat Biotechnol
, vol.15
, pp. 142-145
-
-
Fischer, M.1
-
26
-
-
0033810515
-
Liver regeneration induced by a designer human IL-6/sIL-6R fusion protein reverses severe hepatocellular injury
-
Galun E et al (2000) Liver regeneration induced by a designer human IL-6/sIL-6R fusion protein reverses severe hepatocellular injury. FASEB J 14: 1979-1987
-
(2000)
FASEB J
, vol.14
, pp. 1979-1987
-
-
Galun, E.1
-
27
-
-
0034464010
-
Combined interleukin 6 and soluble interleukin 6 receptor accelerates murine liver regeneration
-
Peters M et al (2000) Combined interleukin 6 and soluble interleukin 6 receptor accelerates murine liver regeneration. Gastroenterology 119: 1663-1671
-
(2000)
Gastroenterology
, vol.119
, pp. 1663-1671
-
-
Peters, M.1
-
28
-
-
0032539893
-
Sympathetic neurons can produce and respond to interleukin 6
-
Marz P et al (1998) Sympathetic neurons can produce and respond to interleukin 6. Proc Natl Acad Sci U S A 95: 3251-3256
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 3251-3256
-
-
Marz, P.1
-
29
-
-
0032826994
-
Neural activities of IL-6- type cytokines often depend on soluble cytokine receptors
-
Marz P et al (1999) Neural activities of IL-6- type cytokines often depend on soluble cytokine receptors. Eur J Neurosci 11: 2995-3004
-
(1999)
Eur J Neurosci
, vol.11
, pp. 2995-3004
-
-
Marz, P.1
-
30
-
-
61849112508
-
Interleukin-6 and neural stem cells: More than gliogenesis
-
Islam O et al (2009) Interleukin-6 and neural stem cells: more than gliogenesis. Mol Biol Cell 20: 188-199
-
(2009)
Mol Biol Cell
, vol.20
, pp. 188-199
-
-
Islam, O.1
-
31
-
-
0032846613
-
Novel path to activation of vascular smooth muscle cells: Up-regulation of gp130 creates an autocrine activation loop by IL-6 and its soluble receptor
-
Klouche M et al (1999) Novel path to activation of vascular smooth muscle cells: up-regulation of gp130 creates an autocrine activation loop by IL-6 and its soluble receptor. J Immunol 163: 4583-4589
-
(1999)
J Immunol
, vol.163
, pp. 4583-4589
-
-
Klouche, M.1
-
32
-
-
0035852678
-
Distinct role of gp130 activation in promoting self-renewal divisions by mitogenically stimulated murine hematopoietic stem cells
-
Audet J et al (2001) Distinct role of gp130 activation in promoting self-renewal divisions by mitogenically stimulated murine hematopoietic stem cells. Proc Natl Acad Sci U S A 98: 1757-1762
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 1757-1762
-
-
Audet, J.1
-
33
-
-
0033802580
-
An IL-6/IL-6 soluble receptor (IL-6R) hybrid protein (H-IL-6) induces EPO-independent erythroid differentiation in human CD34(+) cells
-
Baiocchi M et al (2000) An IL-6/IL-6 soluble receptor (IL-6R) hybrid protein (H-IL-6) induces EPO-independent erythroid differentiation in human CD34(+) cells. Cytokine 12: 1395-1399
-
(2000)
Cytokine
, vol.12
, pp. 1395-1399
-
-
Baiocchi, M.1
-
34
-
-
46949106013
-
The transcription factor repertoire of Flt3+ hematopoietic stem cells
-
Hieronymus T et al (2008) The transcription factor repertoire of Flt3+ hematopoietic stem cells. Cells Tissues Organs 188: 103-115
-
(2008)
Cells Tissues Organs
, vol.188
, pp. 103-115
-
-
Hieronymus, T.1
-
35
-
-
20044384182
-
Progressive and controlled development of mouse dendritic cells from Flt3+CD11b+ progenitors in vitro
-
Hieronymus T et al (2005) Progressive and controlled development of mouse dendritic cells from Flt3+CD11b+ progenitors in vitro. J Immunol 174: 2552-2562
-
(2005)
J Immunol
, vol.174
, pp. 2552-2562
-
-
Hieronymus, T.1
-
36
-
-
84855469209
-
Polycomb group protein bmi1 promotes hematopoietic cell development from embryonic stem cells
-
Ding X et al (2012) Polycomb group protein bmi1 promotes hematopoietic cell development from embryonic stem cells. Stem Cells Dev 21: 121-132
-
(2012)
Stem Cells Dev
, vol.21
, pp. 121-132
-
-
Ding, X.1
-
37
-
-
0037386339
-
Transcriptional profiling identifies Id2 function in dendritic cell development
-
Hacker C et al (2003) Transcriptional profiling identifies Id2 function in dendritic cell development. Nat Immunol 4: 380-386
-
(2003)
Nat Immunol
, vol.4
, pp. 380-386
-
-
Hacker, C.1
-
38
-
-
84860228654
-
Dendritic cell lineage commitment is instructed by distinct cytokine signals
-
Sere KM et al (2011) Dendritic cell lineage commitment is instructed by distinct cytokine signals. Eur J Cell Biol 91: 515-523
-
(2011)
Eur J Cell Biol
, vol.91
, pp. 515-523
-
-
Sere, K.M.1
-
39
-
-
3542996260
-
Maintenance of pluripotency in human embryonic stem cells is STAT3 independent
-
Humphrey RK et al (2004) Maintenance of pluripotency in human embryonic stem cells is STAT3 independent. Stem Cells 22: 522-530
-
(2004)
Stem Cells
, vol.22
, pp. 522-530
-
-
Humphrey, R.K.1
-
40
-
-
0036219910
-
Ligand/receptor signaling threshold (LIST) model accounts for gp130-mediated embryonic stem cell selfrenewal responses to LIF and HIL-6
-
Viswanathan S et al (2002) Ligand/receptor signaling threshold (LIST) model accounts for gp130-mediated embryonic stem cell selfrenewal responses to LIF and HIL-6. Stem Cells 20: 119-138
-
(2002)
Stem Cells
, vol.20
, pp. 119-138
-
-
Viswanathan, S.1
-
41
-
-
0035160256
-
Soluble gp130 is the natural inhibitor of soluble interleukin-6 receptor transsignaling responses
-
Jostock T et al (2001) Soluble gp130 is the natural inhibitor of soluble interleukin-6 receptor transsignaling responses. Eur J Biochem 268: 160-167
-
(2001)
Eur J Biochem
, vol.268
, pp. 160-167
-
-
Jostock, T.1
-
42
-
-
0042834261
-
Soluble IL-6 receptor governs IL-6 activity in experimental arthritis: Blockade of arthritis severity by soluble glycoprotein 130
-
Nowell MA et al (2003) Soluble IL-6 receptor governs IL-6 activity in experimental arthritis: blockade of arthritis severity by soluble glycoprotein 130. J Immunol 171: 3202-3209
-
(2003)
J Immunol
, vol.171
, pp. 3202-3209
-
-
Nowell, M.A.1
-
43
-
-
59849091830
-
Therapeutic targeting of IL-6 trans signaling counteracts STAT3 control of experimental inflammatory arthritis
-
Nowell MA et al (2009) Therapeutic targeting of IL-6 trans signaling counteracts STAT3 control of experimental inflammatory arthritis. J Immunol 182: 613-622
-
(2009)
J Immunol
, vol.182
, pp. 613-622
-
-
Nowell, M.A.1
-
44
-
-
33646469222
-
Functional characterization of a soluble gp130 isoform and its therapeutic capacity in an experimental model of inflammatory arthritis
-
Richards PJ et al (2006) Functional characterization of a soluble gp130 isoform and its therapeutic capacity in an experimental model of inflammatory arthritis. Arthritis Rheum 54: 1662-1672
-
(2006)
Arthritis Rheum
, vol.54
, pp. 1662-1672
-
-
Richards, P.J.1
-
45
-
-
0034960582
-
Il-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation
-
Hurst SM et al (2001) Il-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation. Immunity 14: 705-714
-
(2001)
Immunity
, vol.14
, pp. 705-714
-
-
Hurst, S.M.1
-
46
-
-
79957656408
-
Selective blockade of interleukin-6 trans-signaling improves survival in a murine polymicrobial sepsis model
-
Barkhausen T et al (2011) Selective blockade of interleukin-6 trans-signaling improves survival in a murine polymicrobial sepsis model. Crit Care Med 39: 1407-1413
-
(2011)
Crit Care Med
, vol.39
, pp. 1407-1413
-
-
Barkhausen, T.1
-
47
-
-
79251578016
-
IL-6 trans-signaling modulates TLR4-dependent inflammatory responses via STAT3
-
Greenhill CJ et al (2011) IL-6 trans-signaling modulates TLR4-dependent inflammatory responses via STAT3. J Immunol 186: 1199-1208
-
(2011)
J Immunol
, vol.186
, pp. 1199-1208
-
-
Greenhill, C.J.1
-
48
-
-
18344410191
-
Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: Evidence in crohn disease and experimental colitis in vivo
-
Atreya R et al (2000) Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: evidence in crohn disease and experimental colitis in vivo. Nat Med 6: 583-588
-
(2000)
Nat Med
, vol.6
, pp. 583-588
-
-
Atreya, R.1
-
49
-
-
33747774200
-
STAT3 activation via interleukin 6 trans-signalling contributes to ileitis in SAMP1/Yit mice
-
Mitsuyama K et al (2006) STAT3 activation via interleukin 6 trans-signalling contributes to ileitis in SAMP1/Yit mice. Gut 55: 1263-1269
-
(2006)
Gut
, vol.55
, pp. 1263-1269
-
-
Mitsuyama, K.1
-
50
-
-
5644252874
-
TGF-beta suppresses tumor progression in colon cancer by inhibition of IL-6 trans-signaling
-
Becker C et al (2004) TGF-beta suppresses tumor progression in colon cancer by inhibition of IL-6 trans-signaling. Immunity 21: 491-501
-
(2004)
Immunity
, vol.21
, pp. 491-501
-
-
Becker, C.1
-
51
-
-
23644436122
-
IL-6 signaling promotes tumor growth in colorectal cancer
-
Becker C et al (2005) IL-6 signaling promotes tumor growth in colorectal cancer. Cell Cycle 4: 217-220
-
(2005)
Cell Cycle
, vol.4
, pp. 217-220
-
-
Becker, C.1
-
52
-
-
77949326158
-
Essential roles of IL-6 trans-signaling in colonic epithelial cells, induced by the IL-6/soluble-IL-6 receptor derived from lamina propria macrophages, on the development of colitis-associated premalignant cancer in a murine model
-
Matsumoto S et al (2010) Essential roles of IL-6 trans-signaling in colonic epithelial cells, induced by the IL-6/soluble-IL-6 receptor derived from lamina propria macrophages, on the development of colitis-associated premalignant cancer in a murine model. J Immunol 184: 1543-1551
-
(2010)
J Immunol
, vol.184
, pp. 1543-1551
-
-
Matsumoto, S.1
-
53
-
-
78751549236
-
IL-6 trans-signaling in formation and progression of malignant ascites in ovarian cancer
-
Lo CW et al (2011) IL-6 trans-signaling in formation and progression of malignant ascites in ovarian cancer. Cancer Res 71: 424-434
-
(2011)
Cancer Res
, vol.71
, pp. 424-434
-
-
Lo, C.W.1
-
54
-
-
79953756112
-
Stat3/Socs3 activation by IL-6 transsignaling promotes progression of pancreatic intraepithelial neoplasia and development of pancreatic cancer
-
Lesina M et al (2011) Stat3/Socs3 activation by IL-6 transsignaling promotes progression of pancreatic intraepithelial neoplasia and development of pancreatic cancer. Cancer Cell 19: 456-469
-
(2011)
Cancer Cell
, vol.19
, pp. 456-469
-
-
Lesina, M.1
-
55
-
-
79955650634
-
The pro- and antiinflammatory properties of the cytokine interleukin-6
-
Scheller J et al (2011) The pro- and antiinflammatory properties of the cytokine interleukin-6. Biochim Biophys Acta 1813: 878-888
-
(2011)
Biochim Biophys Acta
, vol.1813
, pp. 878-888
-
-
Scheller, J.1
-
56
-
-
0025190892
-
Interleukin-6 and the acute phase response
-
Heinrich PC et al (1990) Interleukin-6 and the acute phase response. Biochem J 265: 621-636
-
(1990)
Biochem J
, vol.265
, pp. 621-636
-
-
Heinrich, P.C.1
-
57
-
-
58649101347
-
Gp130-mediated Stat3 activation in enterocytes regulates cell survival and cell-cycle progression during colitis-associated tumorigenesis
-
Bollrath J et al (2009) gp130-mediated Stat3 activation in enterocytes regulates cell survival and cell-cycle progression during colitis-associated tumorigenesis. Cancer Cell 15: 91-102
-
(2009)
Cancer Cell
, vol.15
, pp. 91-102
-
-
Bollrath, J.1
-
58
-
-
58649108302
-
IL-6 and STAT3 signaling is required for survival of intestinal epithelial cells and colitis associated cancer
-
Grivennikov S et al (2009) IL-6 and STAT3 signaling is required for survival of intestinal epithelial cells and colitis associated cancer. Cancer Cell 16: 103-113
-
(2009)
Cancer Cell
, vol.16
, pp. 103-113
-
-
Grivennikov, S.1
-
59
-
-
0346157324
-
Acquiring signalling specificity from the cytokine receptor gp130
-
Ernst M, Jenkins BJ (2004) Acquiring signalling specificity from the cytokine receptor gp130. Trends Genet 20: 23-32
-
(2004)
Trends Genet
, vol.20
, pp. 23-32
-
-
Ernst, M.1
Jenkins, B.J.2
-
60
-
-
0024245022
-
Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides
-
Smith AG et al (1988) Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides. Nature 336: 688-690
-
(1988)
Nature
, vol.336
, pp. 688-690
-
-
Smith, A.G.1
-
61
-
-
0033517123
-
STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells
-
Matsuda T et al (1999) STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells. EMBO J 18: 4261-4269
-
(1999)
EMBO J
, vol.18
, pp. 4261-4269
-
-
Matsuda, T.1
-
62
-
-
44349170450
-
The ground state of embryonic stem cell self-renewal
-
Ying QL et al (2008) The ground state of embryonic stem cell self-renewal. Nature 453: 519-523
-
(2008)
Nature
, vol.453
, pp. 519-523
-
-
Ying, Q.L.1
-
63
-
-
0029846756
-
Liver failure and defective hepatocyte regeneration in interleukin-6-deficient mice
-
Cressman DE et al (1996) Liver failure and defective hepatocyte regeneration in interleukin-6-deficient mice. Science 274: 1379-1383
-
(1996)
Science
, vol.274
, pp. 1379-1383
-
-
Cressman, D.E.1
-
64
-
-
0034985726
-
Hyper-IL-6 gene therapy reverses fulminant hepatic failure
-
Hecht N et al (2001) Hyper-IL-6 gene therapy reverses fulminant hepatic failure. Mol Ther 3: 683-687
-
(2001)
Mol Ther
, vol.3
, pp. 683-687
-
-
Hecht, N.1
-
65
-
-
79954895368
-
Early hepatocyte DNA synthetic response posthepatectomy is modulated by IL-6 trans-signaling and PI3K/AKT activation
-
Nechemia-Arbely Y et al (2011) Early hepatocyte DNA synthetic response posthepatectomy is modulated by IL-6 trans-signaling and PI3K/AKT activation. J Hepatol 54: 922-929
-
(2011)
J Hepatol
, vol.54
, pp. 922-929
-
-
Nechemia-Arbely, Y.1
-
66
-
-
48049096638
-
IL-6/IL-6R axis plays a critical role in acute kidney injury
-
Nechemia-Arbely Y et al (2008) IL-6/IL-6R axis plays a critical role in acute kidney injury. J Am Soc Nephrol 19: 1106-1115
-
(2008)
J Am Soc Nephrol
, vol.19
, pp. 1106-1115
-
-
Nechemia-Arbely, Y.1
-
67
-
-
77955348535
-
Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice
-
Chalaris A et al (2010) Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice. J Exp Med 207: 1617-1624
-
(2010)
J Exp Med
, vol.207
, pp. 1617-1624
-
-
Chalaris, A.1
-
68
-
-
79955456934
-
Species specificity of ADAM10 and ADAM17 proteins in interleukin- 6 (IL-6) trans-signaling and novel role of ADAM10 in inducible IL-6 receptor shedding
-
Garbers C et al (2011) Species specificity of ADAM10 and ADAM17 proteins in interleukin- 6 (IL-6) trans-signaling and novel role of ADAM10 in inducible IL-6 receptor shedding. J Biol Chem 286: 14804-14811
-
(2011)
J Biol Chem
, vol.286
, pp. 14804-14811
-
-
Garbers, C.1
-
69
-
-
34548856204
-
Apoptosis is a natural stimulus of IL6R shedding and contributes to the proinflammatory trans-signaling function of neutrophils
-
Chalaris A et al (2007) Apoptosis is a natural stimulus of IL6R shedding and contributes to the proinflammatory trans-signaling function of neutrophils. Blood 110: 1748-1755
-
(2007)
Blood
, vol.110
, pp. 1748-1755
-
-
Chalaris, A.1
-
70
-
-
25144477563
-
Interleukin-6/soluble interleukin-6 receptor complex reduces infarct size via inhibiting myocardial apoptosis
-
Matsushita K et al (2005) Interleukin-6/soluble interleukin-6 receptor complex reduces infarct size via inhibiting myocardial apoptosis. Lab Invest 85: 1210-1223
-
(2005)
Lab Invest
, vol.85
, pp. 1210-1223
-
-
Matsushita, K.1
-
71
-
-
84055199890
-
Fate tracing of mature hepatocytes in mouse liver homeostasis and regeneration
-
Malato Y et al (2011) Fate tracing of mature hepatocytes in mouse liver homeostasis and regeneration. J Clin Invest 121: 4850-4860
-
(2011)
J Clin Invest
, vol.121
, pp. 4850-4860
-
-
Malato, Y.1
-
72
-
-
50249150340
-
A reproducible and well-tolerated method for 2/3 partial hepatectomy in mice
-
Mitchell C, Willenbring H (2008) A reproducible and well-tolerated method for 2/3 partial hepatectomy in mice. Nat Protoc 3: 1167-1170
-
(2008)
Nat Protoc
, vol.3
, pp. 1167-1170
-
-
Mitchell, C.1
Willenbring, H.2
-
73
-
-
48249122445
-
PI3K/Akt activation is critical for early hepatic regeneration after partial hepatectomy
-
Jackson LN et al (2008) PI3K/Akt activation is critical for early hepatic regeneration after partial hepatectomy. Am J Physiol Gastrointest Liver Physiol 294:G1401-G1410
-
(2008)
Am J Physiol Gastrointest Liver Physiol
, vol.294
-
-
Jackson, L.N.1
-
74
-
-
0032190524
-
Coexpression of IL-6 and soluble IL-6R causes nodular regenerative hyperplasia and adenomas of the liver
-
Maione D et al (1998) Coexpression of IL-6 and soluble IL-6R causes nodular regenerative hyperplasia and adenomas of the liver. EMBO J 17: 5588-5597
-
(1998)
EMBO J
, vol.17
, pp. 5588-5597
-
-
Maione, D.1
-
75
-
-
0031858640
-
Hepatocellular hyperplasia, plasmacytoma formation, and extramedullary hematopoiesis in interleukin (IL)-6/soluble IL-6 receptor double-transgenic mice
-
Schirmacher P et al (1998) Hepatocellular hyperplasia, plasmacytoma formation, and extramedullary hematopoiesis in interleukin (IL)-6/soluble IL-6 receptor double-transgenic mice. Am J Pathol 153: 639-648
-
(1998)
Am J Pathol
, vol.153
, pp. 639-648
-
-
Schirmacher, P.1
-
76
-
-
0032194108
-
In vivo and in vitro activities of the gp130-stimulating designer cytokine Hyper-IL-6
-
Peters M et al (1998) In vivo and in vitro activities of the gp130-stimulating designer cytokine Hyper-IL-6. J Immunol 161: 3575-3581
-
(1998)
J Immunol
, vol.161
, pp. 3575-3581
-
-
Peters, M.1
-
77
-
-
73649128882
-
Interleukin-6 transsignaling regulates glycogen consumption after D -galactosamine-induced liver damage
-
Drucker C et al (2009) Interleukin-6 transsignaling regulates glycogen consumption after D -galactosamine-induced liver damage. J Interferon Cytokine Res 29: 711-718
-
(2009)
J Interferon Cytokine Res
, vol.29
, pp. 711-718
-
-
Drucker, C.1
-
78
-
-
38749084203
-
Regulation of liver regeneration and hepatocarcinogenesis by suppressor of cytokine signaling 3
-
Riehle KJ et al (2008) Regulation of liver regeneration and hepatocarcinogenesis by suppressor of cytokine signaling 3. J Exp Med 205: 91-103
-
(2008)
J Exp Med
, vol.205
, pp. 91-103
-
-
Riehle, K.J.1
-
79
-
-
66949144423
-
The regulation of liver cell survival by complement
-
Markiewski MM et al (2009) The regulation of liver cell survival by complement. J Immunol 182: 5412-5418
-
(2009)
J Immunol
, vol.182
, pp. 5412-5418
-
-
Markiewski, M.M.1
-
80
-
-
18244419398
-
Extramedullary expansion of hematopoietic progenitor cells in interleukin (IL)-6-sIL-6R double transgenic mice
-
Peters M et al (1997) Extramedullary expansion of hematopoietic progenitor cells in interleukin (IL)-6-sIL-6R double transgenic mice. J Exp Med 185: 755-766
-
(1997)
J Exp Med
, vol.185
, pp. 755-766
-
-
Peters, M.1
-
81
-
-
0029863504
-
The function of the soluble interleukin 6 (IL-6) receptor in vivo: Sensitization of human soluble IL-6 receptor transgenic mice towards IL-6 and prolongation of the plasma half-life of IL-6
-
Peters M et al (1996) The function of the soluble interleukin 6 (IL-6) receptor in vivo: sensitization of human soluble IL-6 receptor transgenic mice towards IL-6 and prolongation of the plasma half-life of IL-6. J Exp Med 183: 1399-1406
-
(1996)
J Exp Med
, vol.183
, pp. 1399-1406
-
-
Peters, M.1
-
82
-
-
0025881291
-
Structural and functional studies on the human hepatic interleukin- 6 receptor. Molecular cloning and overexpression in HepG2 cells
-
Schooltink H et al (1991) Structural and functional studies on the human hepatic interleukin- 6 receptor. Molecular cloning and overexpression in HepG2 cells. Biochem J 277(Pt 3): 659-664
-
(1991)
Biochem J
, vol.277
, Issue.PART 3
, pp. 659-664
-
-
Schooltink, H.1
-
83
-
-
77956194104
-
The STATs on naive iPSC reprogramming
-
Hanna JH (2010) The STATs on naive iPSC reprogramming. Cell Stem Cell 7: 274-276
-
(2010)
Cell Stem Cell
, vol.7
, pp. 274-276
-
-
Hanna, J.H.1
-
84
-
-
33745598848
-
Forced dimerization of gp130 leads to constitutive STAT3 activation, cytokine-independent growth, and blockade of differentiation of embryonic stem cells
-
Stuhlmann-Laeisz C et al (2006) Forced dimerization of gp130 leads to constitutive STAT3 activation, cytokine-independent growth, and blockade of differentiation of embryonic stem cells. Mol Biol Cell 17: 2986-2995
-
(2006)
Mol Biol Cell
, vol.17
, pp. 2986-2995
-
-
Stuhlmann-Laeisz, C.1
-
85
-
-
37449022587
-
Interleukin-6 is an essential regulator of satellite cell-mediated skeletal muscle hypertrophy
-
Serrano AL et al (2008) Interleukin-6 is an essential regulator of satellite cell-mediated skeletal muscle hypertrophy. Cell Metab 7: 33-44
-
(2008)
Cell Metab
, vol.7
, pp. 33-44
-
-
Serrano, A.L.1
-
86
-
-
80053552289
-
Mesenchymal stem cells: Biology, pathophysiology, translationalfindings, and therapeutic implications for cardiac disease
-
Williams AR, Hare JM (2011) Mesenchymal stem cells: biology, pathophysiology, translationalfindings, and therapeutic implications for cardiac disease. Circ Res 109: 923-940
-
(2011)
Circ Res
, vol.109
, pp. 923-940
-
-
Williams, A.R.1
Hare, J.M.2
-
87
-
-
79952118341
-
Activation of interleukin- 6-induced glycoprotein 130/signal transducer and activator of transcription 3 pathway in mesenchymal stem cells enhances hepatic differentiation, proliferation, and liver regeneration
-
Lam SP et al (2010) Activation of interleukin- 6-induced glycoprotein 130/signal transducer and activator of transcription 3 pathway in mesenchymal stem cells enhances hepatic differentiation, proliferation, and liver regeneration. Liver Transpl 16: 1195-1206
-
(2010)
Liver Transpl
, vol.16
, pp. 1195-1206
-
-
Lam, S.P.1
-
88
-
-
33847738629
-
Opposing roles of gp130-mediated STAT-3 and ERK-1/2 signaling in liver progenitor cell migration and proliferation
-
Yeoh GC et al (2007) Opposing roles of gp130-mediated STAT-3 and ERK-1/2 signaling in liver progenitor cell migration and proliferation. Hepatology 45: 486-494
-
(2007)
Hepatology
, vol.45
, pp. 486-494
-
-
Yeoh, G.C.1
-
89
-
-
0034956260
-
Gp130-stimulating designer cytokine Hyper-interleukin-6 synergizes with murine stroma for long-term survival of primitive human hematopoietic progenitor cells
-
Gotze KS et al (2001) gp130-stimulating designer cytokine Hyper-interleukin-6 synergizes with murine stroma for long-term survival of primitive human hematopoietic progenitor cells. Exp Hematol 29: 822-832
-
(2001)
Exp Hematol
, vol.29
, pp. 822-832
-
-
Gotze, K.S.1
-
90
-
-
0033762663
-
Signal through gp130 activated by soluble interleukin (IL)-6 receptor (R) and IL-6 or IL-6R/IL-6 fusion protein enhances ex vivo expansion of human peripheral blood-derived hematopoietic progenitors
-
Kimura T et al (2000) Signal through gp130 activated by soluble interleukin (IL)-6 receptor (R) and IL-6 or IL-6R/IL-6 fusion protein enhances ex vivo expansion of human peripheral blood-derived hematopoietic progenitors. Stem Cells 18: 444-452
-
(2000)
Stem Cells
, vol.18
, pp. 444-452
-
-
Kimura, T.1
-
91
-
-
51349133256
-
Interleukin-6 regulates pancreatic alpha-cell mass expansion
-
Ellingsgaard H et al (2008) Interleukin-6 regulates pancreatic alpha-cell mass expansion. Proc Natl Acad Sci U S A 105: 13163-13168
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 13163-13168
-
-
Ellingsgaard, H.1
-
92
-
-
44349149913
-
Molecular dissection of gp130-dependent pathways in hepatocytes during liver regeneration
-
Dierssen U et al (2008) Molecular dissection of gp130-dependent pathways in hepatocytes during liver regeneration. J Biol Chem 283: 9886-9895
-
(2008)
J Biol Chem
, vol.283
, pp. 9886-9895
-
-
Dierssen, U.1
-
93
-
-
0043167910
-
Lack of gp130 expression in hepatocytes promotes liver injury
-
Streetz KL et al (2003) Lack of gp130 expression in hepatocytes promotes liver injury. Gastroenterology 125: 532-543
-
(2003)
Gastroenterology
, vol.125
, pp. 532-543
-
-
Streetz, K.L.1
-
94
-
-
0037648511
-
Interleukin-6/glycoprotein 130-dependent pathways are protective during liver regeneration
-
Wuestefeld T et al (2003) Interleukin-6/glycoprotein 130-dependent pathways are protective during liver regeneration. J Biol Chem 278: 11281-11288
-
(2003)
J Biol Chem
, vol.278
, pp. 11281-11288
-
-
Wuestefeld, T.1
-
95
-
-
30944469496
-
Lack of gp130 expression results in more bacterial infection and higher mortality during chronic cholestasis in mice
-
Wuestefeld T et al (2005) Lack of gp130 expression results in more bacterial infection and higher mortality during chronic cholestasis in mice. Hepatology 42: 1082-1090
-
(2005)
Hepatology
, vol.42
, pp. 1082-1090
-
-
Wuestefeld, T.1
-
96
-
-
16844387413
-
The IL-6-gp130-STAT3 pathway in hepatocytes triggers liver protection in T cell-mediated liver injury
-
Klein C et al (2005) The IL-6-gp130-STAT3 pathway in hepatocytes triggers liver protection in T cell-mediated liver injury. J Clin Invest 115: 860-869
-
(2005)
J Clin Invest
, vol.115
, pp. 860-869
-
-
Klein, C.1
-
97
-
-
44549083391
-
IL-6 Promotes compensatory liver regeneration in cirrhotic rat after partial hepatectomy
-
Tiberio GA et al (2008) IL-6 Promotes compensatory liver regeneration in cirrhotic rat after partial hepatectomy. Cytokine 42: 372-378
-
(2008)
Cytokine
, vol.42
, pp. 372-378
-
-
Tiberio, G.A.1
-
98
-
-
34250183381
-
Interleukin-6 sustains hepatic regeneration in cirrhotic rat
-
Tiberio GA et al (2007) Interleukin-6 sustains hepatic regeneration in cirrhotic rat. Hepatogastroenterology 54: 878-883
-
(2007)
Hepatogastroenterology
, vol.54
, pp. 878-883
-
-
Tiberio, G.A.1
-
99
-
-
77956649996
-
Role of IL-6 trans-signaling in CCl induced liver damage
-
Gewiese-Rabsch J et al (2010) Role of IL-6 trans-signaling in CCl induced liver damage. Biochim Biophys Acta 1802: 1054-1061
-
(2010)
Biochim Biophys Acta
, vol.1802
, pp. 1054-1061
-
-
Gewiese-Rabsch, J.1
-
100
-
-
34548788461
-
Interleukin-6 inhibits oxidative injury and necrosis after extreme liver resection
-
Jin X et al (2007) Interleukin-6 inhibits oxidative injury and necrosis after extreme liver resection. Hepatology 46: 802-812
-
(2007)
Hepatology
, vol.46
, pp. 802-812
-
-
Jin, X.1
-
101
-
-
45349102930
-
SOCS3 negatively regulates the gp130-STAT3 pathway in mouse skin wound healing
-
Zhu BM et al (2008) SOCS3 negatively regulates the gp130-STAT3 pathway in mouse skin wound healing. J Invest Dermatol 128: 1821-1829
-
(2008)
J Invest Dermatol
, vol.128
, pp. 1821-1829
-
-
Zhu, B.M.1
-
102
-
-
20444430064
-
Many good reasons to have STAT3 in the heart
-
Hilfiker-Kleiner D et al (2005) Many good reasons to have STAT3 in the heart. Pharmacol Ther 107: 131-137
-
(2005)
Pharmacol Ther
, vol.107
, pp. 131-137
-
-
Hilfiker-Kleiner, D.1
-
103
-
-
79957497037
-
Intravenous gene therapy with PIM-1 via a cardiotropic viral vector halts the progression of diabetic cardiomyopathy through promotion of prosurvival signaling
-
Katare R et al (2011) Intravenous gene therapy with PIM-1 via a cardiotropic viral vector halts the progression of diabetic cardiomyopathy through promotion of prosurvival signaling. Circ Res 108: 1238-1251
-
(2011)
Circ Res
, vol.108
, pp. 1238-1251
-
-
Katare, R.1
-
104
-
-
79953678403
-
The zebrafish heart regenerates after cryoinjury-induced myocardial infarction
-
Chablais F et al (2011) The zebrafish heart regenerates after cryoinjury-induced myocardial infarction. BMC Dev Biol 11:21
-
(2011)
BMC Dev Biol
, vol.11
, pp. 21
-
-
Chablais, F.1
-
105
-
-
77950200829
-
Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation
-
Jopling C et al (2010) Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation. Nature 464: 606-609
-
(2010)
Nature
, vol.464
, pp. 606-609
-
-
Jopling, C.1
-
106
-
-
79954522898
-
Regeneration of cryoinjury induced necrotic heart lesions in zebrafish is associated with epicardial activation and cardiomyocyte proliferation
-
Schnabel K et al (2011) Regeneration of cryoinjury induced necrotic heart lesions in zebrafish is associated with epicardial activation and cardiomyocyte proliferation. PLoS One 6:e18503
-
(2011)
PLoS One
, vol.6
-
-
Schnabel, K.1
-
107
-
-
79952065525
-
Transient regenerative potential of the neonatal mouse heart
-
Porrello ER et al (2011) Transient regenerative potential of the neonatal mouse heart. Science 331: 1078-1080
-
(2011)
Science
, vol.331
, pp. 1078-1080
-
-
Porrello, E.R.1
-
108
-
-
46449089721
-
A myocardial lineage derives from Tbx18 epicardial cells
-
Cai CL et al (2008) A myocardial lineage derives from Tbx18 epicardial cells. Nature 454: 104-108
-
(2008)
Nature
, vol.454
, pp. 104-108
-
-
Cai, C.L.1
-
109
-
-
46449138664
-
Epicardial progenitors contribute to the cardiomyocyte lineage in the developing heart
-
Zhou B et al (2008) Epicardial progenitors contribute to the cardiomyocyte lineage in the developing heart. Nature 454: 109-113
-
(2008)
Nature
, vol.454
, pp. 109-113
-
-
Zhou, B.1
-
110
-
-
64249107059
-
Evidence for cardiomyocyte renewal in humans
-
Bergmann O et al (2009) Evidence for cardiomyocyte renewal in humans. Science 324: 98-102
-
(2009)
Science
, vol.324
, pp. 98-102
-
-
Bergmann, O.1
-
111
-
-
79952070542
-
A murine model of inducible, cardiac-specific deletion of STAT3: Its use to determine the role of STAT3 in the upregulation of cardioprotective proteins by ischemic preconditioning
-
Bolli R et al (2011) A murine model of inducible, cardiac-specific deletion of STAT3: its use to determine the role of STAT3 in the upregulation of cardioprotective proteins by ischemic preconditioning. J Mol Cell Cardiol 50: 589-597
-
(2011)
J Mol Cell Cardiol
, vol.50
, pp. 589-597
-
-
Bolli, R.1
-
112
-
-
80053261320
-
SDF-1/CXCR4 mediates acute protection of cardiac function through myocardial STAT3 signaling following global ischemia/reperfusion injury
-
Huang C et al (2011) SDF-1/CXCR4 mediates acute protection of cardiac function through myocardial STAT3 signaling following global ischemia/reperfusion injury. Am J Physiol Heart Circ Physiol 301:H1496-H1505
-
(2011)
Am J Physiol Heart Circ Physiol
, vol.301
-
-
Huang, C.1
-
113
-
-
0033574574
-
Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress
-
Hirota H et al (1999) Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress. Cell 97: 189-198
-
(1999)
Cell
, vol.97
, pp. 189-198
-
-
Hirota, H.1
-
114
-
-
3342889421
-
Signal transducer and activator of transcription 3 is required for myocardial capillary growth, control of interstitial matrix deposition, and heart protection from ischemic injury
-
Hilfiker-Kleiner D et al (2004) Signal transducer and activator of transcription 3 is required for myocardial capillary growth, control of interstitial matrix deposition, and heart protection from ischemic injury. Circ Res 95: 187-195
-
(2004)
Circ Res
, vol.95
, pp. 187-195
-
-
Hilfiker-Kleiner, D.1
-
115
-
-
79958108043
-
Diabetes blockade of sevoflurane postconditioning is not restored by insulin in the rat heart: Phosphorylated signal transducer and activator of transcription 3- and phosphatidylinositol 3-kinasemediated inhibition
-
Drenger B et al (2011) Diabetes blockade of sevoflurane postconditioning is not restored by insulin in the rat heart: phosphorylated signal transducer and activator of transcription 3- and phosphatidylinositol 3-kinasemediated inhibition. Anesthesiology 114: 1364-1372
-
(2011)
Anesthesiology
, vol.114
, pp. 1364-1372
-
-
Drenger, B.1
-
116
-
-
80355128968
-
MicroRNA-1 transfected embryonic stem cells enhance cardiac myocyte differentiation and inhibit apoptosis by modulating the PTEN/Akt pathway in the infarcted heart
-
Glass C, Singla DK (2011) MicroRNA-1 transfected embryonic stem cells enhance cardiac myocyte differentiation and inhibit apoptosis by modulating the PTEN/Akt pathway in the infarcted heart. Am J Physiol Heart Circ Physiol 301:H2038-H2049
-
(2011)
Am J Physiol Heart Circ Physiol
, vol.301
-
-
Glass, C.1
Singla, D.K.2
-
117
-
-
26844537040
-
Hydrophilic bile salt ursodeoxycholic acid protects myocardium against reperfusion injury in a PI3K/Akt dependent pathway
-
Rajesh KG et al (2005) Hydrophilic bile salt ursodeoxycholic acid protects myocardium against reperfusion injury in a PI3K/Akt dependent pathway. J Mol Cell Cardiol 39: 766-776
-
(2005)
J Mol Cell Cardiol
, vol.39
, pp. 766-776
-
-
Rajesh, K.G.1
-
118
-
-
33746257059
-
Granulocyte colony- stimulating factor mediates cardioprotection against ischemia/reperfusion injury via phosphatidylinositol-3-kinase/Akt pathway in canine hearts
-
Takahama H et al (2006) Granulocyte colony- stimulating factor mediates cardioprotection against ischemia/reperfusion injury via phosphatidylinositol-3- kinase/Akt pathway in canine hearts. Cardiovasc Drugs Ther 20: 159-165
-
(2006)
Cardiovasc Drugs Ther
, vol.20
, pp. 159-165
-
-
Takahama, H.1
-
119
-
-
71149106854
-
SOCS3 deletion promotes optic nerve regeneration in vivo
-
Smith PD et al (2009) SOCS3 deletion promotes optic nerve regeneration in vivo. Neuron 64: 617-623
-
(2009)
Neuron
, vol.64
, pp. 617-623
-
-
Smith, P.D.1
-
120
-
-
83555174832
-
Sustained axon regeneration induced by co-deletion of PTEN and SOCS3
-
Sun F et al (2011) Sustained axon regeneration induced by co-deletion of PTEN and SOCS3. Nature 480: 372-375
-
(2011)
Nature
, vol.480
, pp. 372-375
-
-
Sun, F.1
-
121
-
-
0035884814
-
Leukemia inhibitory factor determines the growth status of injured adult sensory neurons
-
Cafferty WB et al (2001) Leukemia inhibitory factor determines the growth status of injured adult sensory neurons. J Neurosci 21: 7161-7170
-
(2001)
J Neurosci
, vol.21
, pp. 7161-7170
-
-
Cafferty, W.B.1
-
122
-
-
33744997909
-
The cytokine interleukin-6 is sufficient but not necessary to mimic the peripheral conditioning lesion effect on axonal growth
-
Cao Z et al (2006) The cytokine interleukin-6 is sufficient but not necessary to mimic the peripheral conditioning lesion effect on axonal growth. J Neurosci 26: 5565-5573
-
(2006)
J Neurosci
, vol.26
, pp. 5565-5573
-
-
Cao, Z.1
-
123
-
-
33748681723
-
Suppressor of cytokine signaling- 3 suppresses the ability of activated signal transducer and activator of transcription-3 to stimulate neurite growth in rat primary sensory neurons
-
Miao T et al (2006) Suppressor of cytokine signaling- 3 suppresses the ability of activated signal transducer and activator of transcription-3 to stimulate neurite growth in rat primary sensory neurons. J Neurosci 26: 9512-9519
-
(2006)
J Neurosci
, vol.26
, pp. 9512-9519
-
-
Miao, T.1
-
124
-
-
77950467139
-
Kidney regeneration
-
Benigni A et al (2010) Kidney regeneration. Lancet 375: 1310-1317
-
(2010)
Lancet
, vol.375
, pp. 1310-1317
-
-
Benigni, A.1
-
125
-
-
0036376913
-
Interleukin-6 stimulates tubular regeneration in rats with glycerolinduced acute renal failure
-
Homsi E et al (2002) Interleukin-6 stimulates tubular regeneration in rats with glycerolinduced acute renal failure. Nephron 92: 192-199
-
(2002)
Nephron
, vol.92
, pp. 192-199
-
-
Homsi, E.1
-
126
-
-
85047695691
-
Interleukin 6 production by human proximal tubular epithelial cells in vitro: Analysis of the effects of interleukin-1 alpha (IL-1 alpha) and other cytokines
-
Boswell RN et al (1994) Interleukin 6 production by human proximal tubular epithelial cells in vitro: analysis of the effects of interleukin-1 alpha (IL-1 alpha) and other cytokines. Nephrol Dial Transplant 9: 599-606
-
(1994)
Nephrol Dial Transplant
, vol.9
, pp. 599-606
-
-
Boswell, R.N.1
-
128
-
-
50249158577
-
Structural organization of a full-length gp130/LIF-R cytokine receptor transmembrane complex
-
Skiniotis G et al (2008) Structural organization of a full-length gp130/LIF-R cytokine receptor transmembrane complex. Mol Cell 31: 737-748
-
(2008)
Mol Cell
, vol.31
, pp. 737-748
-
-
Skiniotis, G.1
-
129
-
-
52949087943
-
Identification of JAK/STAT pathway regulators-insights from RNAi screens
-
Müller P et al (2008) Identification of JAK/STAT pathway regulators-insights from RNAi screens. Semin Cell Dev Biol 19: 360-369
-
(2008)
Semin Cell Dev Biol
, vol.19
, pp. 360-369
-
-
Müller, P.1
|