Early hepatocyte DNA synthetic response posthepatectomy is modulated by IL-6 trans-signaling and PI3K/AKT activation

Journal of Hepatology

Volumn 54, Issue 5, 2011, Pages 922-929

  Nechemia Arbely, Yael ^a   Shriki, Anat ^a   Denz, Ulrich ^a,c   Drucker, Claudia ^b   Scheller, Jürgen ^b   Raub, Jonathan ^a,d   Pappo, Orit ^a   Rose John, Stefan ^b   Galun, Eithan ^a   Axelrod, Jonathan H ^a  

^a HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^b UNIVERSITY OF KIEL   (Germany)

^c UNIVERSITY OF FREIBURG   (Germany)

^d NEW YORK PRESBYTERIAN HOSPITAL   (United States)

Author keywords

HIL 6; IL 6; IL 6 trans signaling; Liver regeneration; PI3K AKT; sgp130; sIL 6R

Indexed keywords

CELL DNA; CYTOKINE RECEPTOR AGONIST; CYTOKINE RECEPTOR ANTAGONIST; INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SCATTER FACTOR; STAT3 PROTEIN; TRANSFORMING GROWTH FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL CYCLE; CONTROLLED STUDY; DNA SYNTHESIS; ENZYME ACTIVATION; ENZYME INHIBITION; IN VIVO STUDY; KUPFFER CELL; LIVER CELL; LIVER REGENERATION; MALE; MITOGENESIS; MITOSIS; MOUSE; NEUTROPHIL; NONHUMAN; PARTIAL HEPATECTOMY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STELLATE CELL;

ANIMALS; GENE EXPRESSION; HEPATECTOMY; HEPATOCYTES; INTERLEUKIN-6; LIVER REGENERATION; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MITOGEN-ACTIVATED PROTEIN KINASES; MITOSIS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, INTERLEUKIN-6; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; TRANSFECTION;

EID: 79954895368     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2010.08.017     Document Type: Article

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