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Volumn 16, Issue 10, 2010, Pages 1195-1206

Activation of interleukin-6-induced glycoprotein 130/signal transducer and activator of transcription 3 pathway in mesenchymal stem cells enhances hepatic differentiation, proliferation, and liver regeneration

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ALBUMIN; ALPHA 1 ANTITRYPSIN; ALPHA FETOPROTEIN; ASPARTATE AMINOTRANSFERASE; BETA CATENIN; BILIRUBIN; BIOLOGICAL MARKER; CCAAT ENHANCER BINDING PROTEIN ALPHA; CD34 ANTIGEN; CYTOKERATIN 18; CYTOKERATIN 19; GALACTOSAMINE; GLYCOPROTEIN GP 130; HEPATOCYTE NUCLEAR FACTOR 3BETA; HYBRID PROTEIN; INTERLEUKIN 6; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN OV6; STAT3 PROTEIN; UNCLASSIFIED DRUG; WNT5A PROTEIN; GREEN FLUORESCENT PROTEIN; IL6ST PROTEIN, RAT; MITOGEN ACTIVATED PROTEIN KINASE; STAT3 PROTEIN, RAT;

EID: 79952118341     PISSN: 15276465     EISSN: 15276473     Source Type: Journal    
DOI: 10.1002/lt.22136     Document Type: Article
Times cited : (49)

References (40)
  • 1
    • 22144491551 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem cells express a restricted set of functionally active chemokine receptors capable of promoting migration to pancreatic islets
    • Sordi V, Malosio ML, Marchesi F, Mercalli A, Melzi R, Giordano T, et al. Bone marrow mesenchymal stem cells express a restricted set of functionally active chemokine receptors capable of promoting migration to pancreatic islets. Blood 2005;106:419-427.
    • (2005) Blood , vol.106 , pp. 419-427
    • Sordi, V.1    Malosio, M.L.2    Marchesi, F.3    Mercalli, A.4    Melzi, R.5    Giordano, T.6
  • 3
    • 65249118823 scopus 로고    scopus 로고
    • In vitro differentiation of embryonic and adult stem cells into hepatocytes: State of the art
    • Snykers S, De Kock J, Rogiers V, Vanhaecke T. In vitro differentiation of embryonic and adult stem cells into hepatocytes: state of the art. Stem Cells 2009;27:577-605.
    • (2009) Stem Cells , vol.27 , pp. 577-605
    • Snykers, S.1    De Kock, J.2    Rogiers, V.3    Vanhaecke, T.4
  • 4
    • 0036106054 scopus 로고    scopus 로고
    • Multipotent adult progenitor cells from bone marrow differentiate into functional hepatocyte-like cells
    • Schwartz RE, Reyes M, Koodie L, Jiang Y, Blackstad M, Lund T, et al. Multipotent adult progenitor cells from bone marrow differentiate into functional hepatocyte-like cells. J Clin Invest 2002;109:1291-1302.
    • (2002) J Clin Invest , vol.109 , pp. 1291-1302
    • Schwartz, R.E.1    Reyes, M.2    Koodie, L.3    Jiang, Y.4    Blackstad, M.5    Lund, T.6
  • 7
    • 34047115205 scopus 로고    scopus 로고
    • Functional integration of hepatocytes derived from human mesenchymal stem cells into mouse livers
    • Aurich I, Mueller LP, Aurich H, Luetzkendorf J, Tisljar K, Dollinger MM, et al. Functional integration of hepatocytes derived from human mesenchymal stem cells into mouse livers. Gut 2007;56:405-415.
    • (2007) Gut , vol.56 , pp. 405-415
    • Aurich, I.1    Mueller, L.P.2    Aurich, H.3    Luetzkendorf, J.4    Tisljar, K.5    Dollinger, M.M.6
  • 8
    • 42549164807 scopus 로고    scopus 로고
    • Wnt signalling and its impact on development and cancer
    • Klaus A, Birchmeier W. Wnt signalling and its impact on development and cancer. Nat Rev Cancer 2008;8: 387-398.
    • (2008) Nat Rev Cancer , vol.8 , pp. 387-398
    • Klaus, A.1    Birchmeier, W.2
  • 9
    • 66149183002 scopus 로고    scopus 로고
    • Beta-Catenin expression in the bone marrow microenvironment is required for long-term maintenance of primitive hematopoietic cells
    • Nemeth MJ, Mak KK, Yang Y, Bodine DM. beta-Catenin expression in the bone marrow microenvironment is required for long-term maintenance of primitive hematopoietic cells. Stem Cells 2009;27:1109-1119.
    • (2009) Stem Cells , vol.27 , pp. 1109-1119
    • Nemeth, M.J.1    Mak, K.K.2    Yang, Y.3    Bodine, D.M.4
  • 10
    • 38349047718 scopus 로고    scopus 로고
    • Down-regulation of Wnt signaling could promote bone marrow-derived mesenchymal stem cells to differentiate into hepatocytes
    • Ke Z, Zhou F, Wang L, Chen S, Liu F, Fan X, et al. Down-regulation of Wnt signaling could promote bone marrow-derived mesenchymal stem cells to differentiate into hepatocytes. Biochem Biophys Res Commun 2008; 367:342-348.
    • (2008) Biochem Biophys Res Commun , vol.367 , pp. 342-348
    • Ke, Z.1    Zhou, F.2    Wang, L.3    Chen, S.4    Liu, F.5    Fan, X.6
  • 11
    • 36148972787 scopus 로고    scopus 로고
    • A role of Wnt/beta-catenin signals in hepatic fate specification of human umbilical cord bloodderived mesenchymal stem cells
    • Yoshida Y, Shimomura T, Sakabe T, Ishii K, Gonda K, Matsuoka S, et al. A role of Wnt/beta-catenin signals in hepatic fate specification of human umbilical cord bloodderived mesenchymal stem cells. Am J Physiol Gastrointest Liver Physiol 2007;293:G1089-G1098.
    • (2007) Am J Physiol Gastrointest Liver Physiol , vol.293
    • Yoshida, Y.1    Shimomura, T.2    Sakabe, T.3    Ishii, K.4    Gonda, K.5    Matsuoka, S.6
  • 12
    • 0043234811 scopus 로고    scopus 로고
    • Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3-independent beta-catenin degradation
    • Topol L, Jiang X, Choi H, Garrett-Beal L, Carolan PJ, Yang Y. Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3-independent beta-catenin degradation. J Cell Biol 2003;162:899-908.
    • (2003) J Cell Biol , vol.162 , pp. 899-908
    • Topol, L.1    Jiang, X.2    Choi, H.3    Garrett-Beal, L.4    Carolan, P.J.5    Yang, Y.6
  • 13
    • 4344708101 scopus 로고    scopus 로고
    • Signals through gp130 upregulate Wnt5a and contribute to cell adhesion in cardiac myocytes
    • Fujio Y, Matsuda T, Oshima Y, Maeda M, Mohri T, Ito T, et al. Signals through gp130 upregulate Wnt5a and contribute to cell adhesion in cardiac myocytes. FEBS Lett 2004;573:202-206.
    • (2004) FEBS Lett , vol.573 , pp. 202-206
    • Fujio, Y.1    Matsuda, T.2    Oshima, Y.3    Maeda, M.4    Mohri, T.5    Ito, T.6
  • 14
    • 0028226196 scopus 로고
    • Soluble receptors for cytokines and growth factors: Generation and biological function
    • Rose-John S, Heinrich PC. Soluble receptors for cytokines and growth factors: generation and biological function. Biochem J 1994;300:281-290.
    • (1994) Biochem J , vol.300 , pp. 281-290
    • Rose-John, S.1    Heinrich, P.C.2
  • 15
    • 33748848714 scopus 로고    scopus 로고
    • Interleukin-6 biology is coordinated by membrane-bound and soluble receptors: Role in inflammation and cancer
    • Rose-John S, Scheller J, Elson G, Jones SA. Interleukin-6 biology is coordinated by membrane-bound and soluble receptors: role in inflammation and cancer. J Leukoc Biol 2006;80:227-236.
    • (2006) J Leukoc Biol , vol.80 , pp. 227-236
    • Rose-John, S.1    Scheller, J.2    Elson, G.3    Jones, S.A.4
  • 16
    • 33646485510 scopus 로고    scopus 로고
    • Serum levels of interleukin-6 and its soluble receptors in patients with hepatitis C virus infection
    • Migita K, Abiru S, Maeda Y, Daikoku M, Ohata K, Nakamura M, et al. Serum levels of interleukin-6 and its soluble receptors in patients with hepatitis C virus infection. Hum Immunol 2006;67:27-32.
    • (2006) Hum Immunol , vol.67 , pp. 27-32
    • Migita, K.1    Abiru, S.2    Maeda, Y.3    Daikoku, M.4    Ohata, K.5    Nakamura, M.6
  • 20
    • 0036031676 scopus 로고    scopus 로고
    • Gp130 activation by soluble interleukin-6 receptor/interleukin-6 enhances osteoblastic differentiation of human bone marrow-derived mesenchymal stem cells
    • Erices A, Conget P, Rojas C, Minguell JJ. Gp130 activation by soluble interleukin-6 receptor/interleukin-6 enhances osteoblastic differentiation of human bone marrow-derived mesenchymal stem cells. Exp Cell Res 2002;280:24-32.
    • (2002) Exp Cell Res , vol.280 , pp. 24-32
    • Erices, A.1    Conget, P.2    Rojas, C.3    Minguell, J.J.4
  • 21
    • 4444336819 scopus 로고    scopus 로고
    • Inhibition of tumor necrosis factor-induced apoptosis in transgenic mouse liver expressing creatine kinase
    • Hatano E, Tanaka A, Kanazawa A, Tsuyuki S, Tsunekawa S, Iwata S, et al. Inhibition of tumor necrosis factor-induced apoptosis in transgenic mouse liver expressing creatine kinase. Liver Int 2004;24:384-393.
    • (2004) Liver Int , vol.24 , pp. 384-393
    • Hatano, E.1    Tanaka, A.2    Kanazawa, A.3    Tsuyuki, S.4    Tsunekawa, S.5    Iwata, S.6
  • 22
    • 3042841932 scopus 로고    scopus 로고
    • Expression of hepatocyte-like phenotypes in bone marrow stromal cells after HGF induction
    • Wang PP, Wang JH, Yan ZP, Hu MY, Lau GK, Fan ST, et al. Expression of hepatocyte-like phenotypes in bone marrow stromal cells after HGF induction. Biochem Biophys Res Commun 2004;320:712-716.
    • (2004) Biochem Biophys Res Commun , vol.320 , pp. 712-716
    • Wang, P.P.1    Wang, J.H.2    Yan, Z.P.3    Hu, M.Y.4    Lau, G.K.5    Fan, S.T.6
  • 23
    • 0017101039 scopus 로고
    • Preparation of isolated rat liver cells
    • Seglen PO. Preparation of isolated rat liver cells. Methods Cell Biol 1976;13:29-83.
    • (1976) Methods Cell Biol , vol.13 , pp. 29-83
    • Seglen, P.O.1
  • 26
    • 0038157321 scopus 로고    scopus 로고
    • Albumin-expressing hepatocyte-like cells develop in the livers of immune-deficient mice that received transplants of highly purified human hematopoietic stem cells
    • Wang X, Ge S, McNamara G, Hao QL, Crooks GM, Nolta JA. Albumin-expressing hepatocyte-like cells develop in the livers of immune-deficient mice that received transplants of highly purified human hematopoietic stem cells. Blood 2003;101:4201-4208.
    • (2003) Blood , vol.101 , pp. 4201-4208
    • Wang, X.1    Ge, S.2    McNamara, G.3    Hao, Q.L.4    Crooks, G.M.5    Nolta, J.A.6
  • 27
    • 26244435756 scopus 로고    scopus 로고
    • Hepatic potential of bone marrow stromal cells: Development of in vitro co-culture and intra-portal transplantation models
    • Luk JM, Wang PP, Lee CK, Wang JH, Fan ST. Hepatic potential of bone marrow stromal cells: development of in vitro co-culture and intra-portal transplantation models. J Immunol Methods 2005;305:39-47.
    • (2005) J Immunol Methods , vol.305 , pp. 39-47
    • Luk, J.M.1    Wang, P.P.2    Lee, C.K.3    Wang, J.H.4    Fan, S.T.5
  • 28
    • 33746571978 scopus 로고    scopus 로고
    • Differentiating characterization of human umbilical cord blood-derived mesenchymal stem cells in vitro
    • Kang XQ, Zang WJ, Bao LJ, Li DL, Xu XL, Yu XJ. Differentiating characterization of human umbilical cord blood-derived mesenchymal stem cells in vitro. Cell Biol Int 2006;30:569-575.
    • (2006) Cell Biol Int , vol.30 , pp. 569-575
    • Kang, X.Q.1    Zang, W.J.2    Bao, L.J.3    Li, D.L.4    Xu, X.L.5    Yu, X.J.6
  • 30
    • 48749130398 scopus 로고    scopus 로고
    • MAPK/ ERK signaling mediates VEGF-induced bone marrow stem cell differentiation into endothelial cell
    • Xu J, Liu X, Jiang Y, Chu L, Hao H, Liua Z, et al. MAPK/ ERK signaling mediates VEGF-induced bone marrow stem cell differentiation into endothelial cell. J Cell Mol Med 2008;12:2395-2406.
    • (2008) J Cell Mol Med , vol.12 , pp. 2395-2406
    • Xu, J.1    Liu, X.2    Jiang, Y.3    Chu, L.4    Hao, H.5    Liua, Z.6
  • 31
    • 33744977046 scopus 로고    scopus 로고
    • Epidermal growth factor is a neuronal differentiation factor for retinal stem cells in vitro
    • Angenieux B, Schorderet DF, Arsenijevic Y. Epidermal growth factor is a neuronal differentiation factor for retinal stem cells in vitro. Stem Cells 2006;24:696-706.
    • (2006) Stem Cells , vol.24 , pp. 696-706
    • Angenieux, B.1    Schorderet, D.F.2    Arsenijevic, Y.3
  • 32
    • 0037205315 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3beta: A novel regulator of cardiac hypertrophy and development
    • Hardt SE, Sadoshima J. Glycogen synthase kinase-3beta: a novel regulator of cardiac hypertrophy and development. Circ Res 2002;90:1055-1063.
    • (2002) Circ Res , vol.90 , pp. 1055-1063
    • Hardt, S.E.1    Sadoshima, J.2
  • 33
    • 47349090556 scopus 로고    scopus 로고
    • The role of glycogen synthase kinase-3beta in normal haematopoiesis angiogenesis and leukaemia
    • Holmes T, O'Brien TA, Knight R, Lindeman R, Symonds G, Dolnikov A. The role of glycogen synthase kinase-3beta in normal haematopoiesis, angiogenesis and leukaemia. Curr Med Chem 2008;15:1493-1499.
    • (2008) Curr Med Chem , vol.15 , pp. 1493-1499
    • Holmes, T.1    O'brien, T.A.2    Knight, R.3    Lindeman, R.4    Symonds, G.5    Dolnikov, A.6
  • 35
    • 77950865388 scopus 로고    scopus 로고
    • Wnt5a signaling is involved in the aggressiveness of prostate cancer and expression of metalloproteinase
    • Yamamoto H, Oue N, Sato A, Hasegawa Y, Yamamoto H, Matsubara A, et al. Wnt5a signaling is involved in the aggressiveness of prostate cancer and expression of metalloproteinase. Oncogene 2010;29:2036-2046.
    • (2010) Oncogene , vol.29 , pp. 2036-2046
    • Yamamoto, H.1    Oue, N.2    Sato, A.3    Hasegawa, Y.4    Yamamoto, H.5    Matsubara, A.6
  • 36
    • 0343238244 scopus 로고    scopus 로고
    • Interleukin 6 activates androgen receptor-mediated gene expression through a signal transducer and activator of transcription 3-dependent pathway in LNCaP prostate cancer cells
    • Chen T, Wang LH, Farrar WL. Interleukin 6 activates androgen receptor-mediated gene expression through a signal transducer and activator of transcription 3-dependent pathway in LNCaP prostate cancer cells. Cancer Res 2000;60:2132-2135.
    • (2000) Cancer Res , vol.60 , pp. 2132-2135
    • Chen, T.1    Wang, L.H.2    Farrar, W.L.3
  • 37
    • 0037564511 scopus 로고    scopus 로고
    • Interleukin-6 differentially regulates androgen receptor transactivation via PI3K-Akt STAT3 and MAPK three distinct signal pathways in prostate cancer cells
    • Yang L, Wang L, Lin HK, Kan PY, Xie S, Tsai MY, et al. Interleukin-6 differentially regulates androgen receptor transactivation via PI3K-Akt, STAT3, and MAPK, three distinct signal pathways in prostate cancer cells. Biochem Biophys Res Commun 2003;305:462-469.
    • (2003) Biochem Biophys Res Commun , vol.305 , pp. 462-469
    • Yang, L.1    Wang, L.2    Lin, H.K.3    Kan, P.Y.4    Xie, S.5    Tsai, M.Y.6
  • 38
    • 0036942881 scopus 로고    scopus 로고
    • Soluble interleukin-6 (IL-6) receptor/IL-6 fusion protein enhances in vitro differentiation of purified rat oligodendroglial lineage cells
    • Valerio A, Ferrario M, Dreano M, Garotta G, Spano P, Pizzi M. Soluble interleukin-6 (IL-6) receptor/IL-6 fusion protein enhances in vitro differentiation of purified rat oligodendroglial lineage cells. Mol Cell Neurosci 2002;21:602-615.
    • (2002) Mol Cell Neurosci , vol.21 , pp. 602-615
    • Valerio, A.1    Ferrario, M.2    Dreano, M.3    Garotta, G.4    Spano, P.5    Pizzi, M.6
  • 39
    • 77950628997 scopus 로고    scopus 로고
    • Mesenchymal stem cell-conditioned medium accelerates skin wound healing: An in vitro study of fibroblast and keratinocyte scratch assays
    • Walter MN, Wright KT, Fuller HR, MacNeil S, Johnson WE. Mesenchymal stem cell-conditioned medium accelerates skin wound healing: an in vitro study of fibroblast and keratinocyte scratch assays. Exp Cell Res 2010;316: 1271-1281.
    • (2010) Exp Cell Res , vol.316 , pp. 1271-1281
    • Walter, M.N.1    Wright, K.T.2    Fuller, H.R.3    MacNeil, S.4    Johnson, W.E.5
  • 40
    • 77954189278 scopus 로고    scopus 로고
    • Direct intrathecal implantation of mesenchymal stromal cells leads to enhanced neuroprotection via an NfkappaB mediated increase in interleukin-6 production
    • Walker PA, Harting MT, Jimenez F, Shah SK, Pati S, Dash PK, et al. Direct intrathecal implantation of mesenchymal stromal cells leads to enhanced neuroprotection via an NfkappaB mediated increase in interleukin-6 production. Stem Cells Dev 2010;19:867-876.
    • (2010) Stem Cells Dev , vol.19 , pp. 867-876
    • Walker, P.A.1    Harting, M.T.2    Jimenez, F.3    Shah, S.K.4    Pati, S.5    Dash, P.K.6


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