메뉴 건너뛰기




Volumn 171, Issue 6, 2003, Pages 3202-3209

Soluble IL-6 receptor governs IL-6 activity in experimental arthritis: Blockade of arthritis severity by soluble Glycoprotein 130

Author keywords

[No Author keywords available]

Indexed keywords

BETA CHEMOKINE; CORTICOSTEROID; GLYCOPROTEIN P; HYBRID PROTEIN; HYPERINTERLEUKIN 6; INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR; NONSTEROID ANTIINFLAMMATORY AGENT; SOLUBLE GLYCOPROTEIN GP 130; UNCLASSIFIED DRUG;

EID: 0042834261     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.171.6.3202     Document Type: Article
Times cited : (217)

References (52)
  • 1
    • 0023942493 scopus 로고
    • Interleukin-6 in synovial fluid and serum of patients with rheumatoid arthritis and other inflammatory arthritides
    • Houssiau, F. A., J. Devogelaer, J. Van Damme, C. Nagant de Deuxchaisnes, and J. Van Snick. 1988. Interleukin-6 in synovial fluid and serum of patients with rheumatoid arthritis and other inflammatory arthritides. Arthritis Rheum. 31:784.
    • (1988) Arthritis Rheum. , vol.31 , pp. 784
    • Houssiau, F.A.1    Devogelaer, J.2    Van Damme, J.3    Nagant de Deuxchaisnes, C.4    Van Snick, J.5
  • 6
    • 0030794222 scopus 로고    scopus 로고
    • Interleukin-6 reduces cartilage destruction during experimental arthritis: A study in interleukin-6-deficient mice
    • Van de Loo, F. A., S. Kuiper, F. H. van Enckevort, O. J. Antz, and W. B. van der Berg. 1997. Interleukin-6 reduces cartilage destruction during experimental arthritis: a study in interleukin-6-deficient mice. Am. J. Pathol. 151:177.
    • (1997) Am. J. Pathol. , vol.151 , pp. 177
    • Van de Loo, F.A.1    Kuiper, S.2    Van Enckevort, F.H.3    Antz, O.J.4    Van der Berg, W.B.5
  • 10
    • 0033393367 scopus 로고    scopus 로고
    • Interleukin 6 knock-out mice are resistant to antigen-induced experimental arthritis
    • Boe, A., M. Baiocchi, M. Carbonatto, R. Papoian, and O. Serlupi-Crescenzi. 1999. Interleukin 6 knock-out mice are resistant to antigen-induced experimental arthritis. Cytokine 11:1057.
    • (1999) Cytokine , vol.11 , pp. 1057
    • Boe, A.1    Baiocchi, M.2    Carbonatto, M.3    Papoian, R.4    Serlupi-Crescenzi, O.5
  • 12
    • 0033638233 scopus 로고    scopus 로고
    • Involvement of IL-6, apart from its role in immunity, in mediating a chronic response during experimental arthritis
    • De Hooge, A. S. K., F. A. J. van de Loo, O. J. Arntz, and W. B. van den Berg. 2000. Involvement of IL-6, apart from its role in immunity, in mediating a chronic response during experimental arthritis. Am. J. Pathol. 157:2081.
    • (2000) Am. J. Pathol. , vol.157 , pp. 2081
    • De Hooge, A.S.K.1    Van de Loo, F.A.J.2    Arntz, O.J.3    Van den Berg, W.B.4
  • 13
    • 0027518860 scopus 로고
    • Serum interleukin-6 levels in rheumatoid arthritis: Correlations with clinical and laboratory indexes of disease activity
    • Madhok, R., A. Crilly, J. Watson, and H. A. Capell. 1993. Serum interleukin-6 levels in rheumatoid arthritis: correlations with clinical and laboratory indexes of disease activity. Ann. Rheum. Dis. 52:232.
    • (1993) Ann. Rheum. Dis. , vol.52 , pp. 232
    • Madhok, R.1    Crilly, A.2    Watson, J.3    Capell, H.A.4
  • 14
    • 0032169769 scopus 로고    scopus 로고
    • A possible role for soluble IL-6 receptor in the pathogenesis of systemic onset juvenile chronic arthritis
    • Keul, R., P. C. Heinrich, G. Müller-Newen, K. Muller, and P. Woo. 1998. A possible role for soluble IL-6 receptor in the pathogenesis of systemic onset juvenile chronic arthritis. Cytokine 10:729.
    • (1998) Cytokine , vol.10 , pp. 729
    • Keul, R.1    Heinrich, P.C.2    Müller-Newen, G.3    Muller, K.4    Woo, P.5
  • 15
    • 0027402917 scopus 로고
    • Treatment of severe rheumatoid arthritis by an anti-interleukin 6 monoclonal antibody
    • Wendling, D., A. Racadote, and J. Wijdenes. 1993. Treatment of severe rheumatoid arthritis by an anti-interleukin 6 monoclonal antibody. J. Rheumatol. 20:259.
    • (1993) J. Rheumatol. , vol.20 , pp. 259
    • Wendling, D.1    Racadote, A.2    Wijdenes, J.3
  • 20
    • 0035164602 scopus 로고    scopus 로고
    • The soluble interleukin-6 receptor: Mechanisms of production and implications in disease
    • Jones, S. A., S. Horiuchi, N. Topley, N. Yamamoto, and G. M. Fuller. 2001. The soluble interleukin-6 receptor: mechanisms of production and implications in disease. FASEB J. 15:43.
    • (2001) FASEB J. , vol.15 , pp. 43
    • Jones, S.A.1    Horiuchi, S.2    Topley, N.3    Yamamoto, N.4    Fuller, G.M.5
  • 21
    • 0037064542 scopus 로고    scopus 로고
    • Soluble receptors in cytokine biology: The agonistic properties of the sIL-6R/IL-6 complex
    • Jones, S. A., and S. Rose-John. 2002. Soluble receptors in cytokine biology: the agonistic properties of the sIL-6R/IL-6 complex. Biochim. Biophys. Acta 1592:251.
    • (2002) Biochim. Biophys. Acta , vol.1592 , pp. 251
    • Jones, S.A.1    Rose-John, S.2
  • 23
    • 13344250490 scopus 로고    scopus 로고
    • Interleukin-6 and soluble interleukin-6 receptors in the synovial fluids from rheumatoid arthritis patients are responsible for osteoclast-like cell formation
    • Kotake, S., K. Sato, K. J. Kim, N. Takahashi, N. Udagawa, I. Nakamura, A. Yamaguchi, T. Kishimoto, T. Suda, and S. Kashiwazaki. 1996. Interleukin-6 and soluble interleukin-6 receptors in the synovial fluids from rheumatoid arthritis patients are responsible for osteoclast-like cell formation. J. Bone Miner. Res. 11:88.
    • (1996) J. Bone Miner. Res. , vol.11 , pp. 88
    • Kotake, S.1    Sato, K.2    Kim, K.J.3    Takahashi, N.4    Udagawa, N.5    Nakamura, I.6    Yamaguchi, A.7    Kishimoto, T.8    Suda, T.9    Kashiwazaki, S.10
  • 24
    • 0029060421 scopus 로고
    • Interleukin-6 (IL-6) induces the proliferation of synovial fibroblastic cells in the presence of soluble IL-6 receptor
    • Mihara, M., Y. Moriya, T. Kishimoto, and Y. Oshugi. 1995. Interleukin-6 (IL-6) induces the proliferation of synovial fibroblastic cells in the presence of soluble IL-6 receptor. Br. J. Rheumatol. 34:321.
    • (1995) Br. J. Rheumatol. , vol.34 , pp. 321
    • Mihara, M.1    Moriya, Y.2    Kishimoto, T.3    Oshugi, Y.4
  • 25
    • 0030911246 scopus 로고    scopus 로고
    • Interleukin-6 and its soluble receptor cause a marked induction of collagenase 3 expression in rat osteoblastic cultures
    • Franchimont, N., S. Rydziel, A. M. Delaney, and E. Canalis. 1997. Interleukin-6 and its soluble receptor cause a marked induction of collagenase 3 expression in rat osteoblastic cultures. J. Biol. Chem. 272:12144.
    • (1997) J. Biol. Chem. , vol.272 , pp. 12144
    • Franchimont, N.1    Rydziel, S.2    Delaney, A.M.3    Canalis, E.4
  • 26
    • 0033783333 scopus 로고    scopus 로고
    • IL-6 and its soluble receptor augment aggrecanase-mediated proteoglycan catabolism in articular cartilage
    • Flannery, C. R., C. B. Little, C. E. Hughes, C. L. Curtis, B. Caterson, and S. A. Jones. 2000. IL-6 and its soluble receptor augment aggrecanase-mediated proteoglycan catabolism in articular cartilage. Matrix Biol. 19:549.
    • (2000) Matrix Biol. , vol.19 , pp. 549
    • Flannery, C.R.1    Little, C.B.2    Hughes, C.E.3    Curtis, C.L.4    Caterson, B.5    Jones, S.A.6
  • 29
  • 30
    • 0028087834 scopus 로고
    • Soluble interleukin-6 receptors released from T cell or granulocyte/macrophage cell lines and human peripheral blood mononuclear cells are generated through an alternative splicing mechanism
    • Horiuchi, S., Y. Koyanagi, Y. Zhou, H. Miyamoto, Y. Tanak, M. Waki, A. Matsumoto, M. Yamamoto, and N. Yamamoto. 1994. Soluble interleukin-6 receptors released from T cell or granulocyte/macrophage cell lines and human peripheral blood mononuclear cells are generated through an alternative splicing mechanism. Eur. J. Immunol. 24:1945.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 1945
    • Horiuchi, S.1    Koyanagi, Y.2    Zhou, Y.3    Miyamoto, H.4    Tanak, Y.5    Waki, M.6    Matsumoto, A.7    Yamamoto, M.8    Yamamoto, N.9
  • 31
    • 0031764113 scopus 로고    scopus 로고
    • High-level production of alternatively spliced soluble interleukin-6 receptor in serum of patients with adult T-cell leukemia/HTLV-1-associated myelopathy
    • Horiuchi, S., W. Ampofo, Y. Koyanagi, A. Yamashita, M. Waki, A. Matsumoto, and M. Yamamoto. 1998. High-level production of alternatively spliced soluble interleukin-6 receptor in serum of patients with adult T-cell leukemia/HTLV-1-associated myelopathy. Immunology 95:360.
    • (1998) Immunology , vol.95 , pp. 360
    • Horiuchi, S.1    Ampofo, W.2    Koyanagi, Y.3    Yamashita, A.4    Waki, M.5    Matsumoto, A.6    Yamamoto, M.7
  • 32
    • 0038367278 scopus 로고    scopus 로고
    • Leukocyte migration across human peritoneal mesothelial cells is dependent on directed chemokine secretion and ICAM-1 expression
    • Li, F. K., A. Davenport, R. Robson, P. Loetscher, R. Rothlein, J. D. Williams, and N. Topley. 1998. Leukocyte migration across human peritoneal mesothelial cells is dependent on directed chemokine secretion and ICAM-1 expression. Kidney Int. 54:2170.
    • (1998) Kidney Int. , vol.54 , pp. 2170
    • Li, F.K.1    Davenport, A.2    Robson, R.3    Loetscher, P.4    Rothlein, R.5    Williams, J.D.6    Topley, N.7
  • 34
    • 0031744306 scopus 로고    scopus 로고
    • Serum levels of interleukin-6 type cytokines and soluble interleukin-6 receptor in patients with rheumatoid arthritis
    • Robak, T., A. Gladalska, H. Stepien, and E. Robak. 1998. Serum levels of interleukin-6 type cytokines and soluble interleukin-6 receptor in patients with rheumatoid arthritis. Med. Inflamm. 7:347.
    • (1998) Med. Inflamm. , vol.7 , pp. 347
    • Robak, T.1    Gladalska, A.2    Stepien, H.3    Robak, E.4
  • 36
    • 0035884847 scopus 로고    scopus 로고
    • The IL-6-soluble IL-6Rα autocrine loop of endothelial activation as an intermediate between acute and chronic inflammation: An experimental model involving thrombin
    • Marin, V., F. A. Montero-Julian, S. Gres, V. Boulay, P. Bongrand, C. Farnarier, and G. Kaplanski. 2001. The IL-6-soluble IL-6Rα autocrine loop of endothelial activation as an intermediate between acute and chronic inflammation: an experimental model involving thrombin. J. Immunol. 167:3445.
    • (2001) J. Immunol. , vol.167 , pp. 3445
    • Marin, V.1    Montero-Julian, F.A.2    Gres, S.3    Boulay, V.4    Bongrand, P.5    Farnarier, C.6    Kaplanski, G.7
  • 37
    • 0031471861 scopus 로고    scopus 로고
    • Retrograde inflammatory signaling from neutrophils to endothelial cells by soluble IL-6 receptor α
    • Modur, V., Y. Li, G. A. Zimmerman, S. M. Prescott, and T. M. McIntyre. 1997. Retrograde inflammatory signaling from neutrophils to endothelial cells by soluble IL-6 receptor α. J. Clin. Invest. 100:2752.
    • (1997) J. Clin. Invest. , vol.100 , pp. 2752
    • Modur, V.1    Li, Y.2    Zimmerman, G.A.3    Prescott, S.M.4    McIntyre, T.M.5
  • 39
    • 0034681941 scopus 로고    scopus 로고
    • Enzymatically degraded, nonoxidized LDL induces human vascular smooth muscle cell activation, foam cell transformation and proliferation
    • Klouche, M., S. Rose-John, W. Schmiedt, and S. Bhakdi. 2000. Enzymatically degraded, nonoxidized LDL induces human vascular smooth muscle cell activation, foam cell transformation and proliferation. Circulation 101:1799.
    • (2000) Circulation , vol.101 , pp. 1799
    • Klouche, M.1    Rose-John, S.2    Schmiedt, W.3    Bhakdi, S.4
  • 41
    • 0032212261 scopus 로고    scopus 로고
    • Role of IL-6 and the soluble receptor in inhibition of VCAM-1 gene expression
    • Oh, J. W., N. J. Van Wagoner, S. Rose-John, and E. N. Benveniste. 1998. Role of IL-6 and the soluble receptor in inhibition of VCAM-1 gene expression. J. Immunol. 161:4992.
    • (1998) J. Immunol. , vol.161 , pp. 4992
    • Oh, J.W.1    Van Wagoner, N.J.2    Rose-John, S.3    Benveniste, E.N.4
  • 42
    • 0035423403 scopus 로고    scopus 로고
    • Essential role for neutrophils in the initiation and progression of a murine model of rheumatoid arthritis
    • Wipke, B. T., and P. M. Allen. 1998. Essential role for neutrophils in the initiation and progression of a murine model of rheumatoid arthritis. J. Immunol. 167:1601.
    • (1998) J. Immunol. , vol.167 , pp. 1601
    • Wipke, B.T.1    Allen, P.M.2
  • 43
    • 0036636094 scopus 로고    scopus 로고
    • Apoptosis as a therapeutic tool in rheumatoid arthritis
    • Pope, R. M. 2002. Apoptosis as a therapeutic tool in rheumatoid arthritis. Nat. Rev. Immunol. 2:1.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 1
    • Pope, R.M.1
  • 44
    • 0032499260 scopus 로고    scopus 로고
    • Chemokines and leukocyte traffic
    • Baggiolini, M. 1998. Chemokines and leukocyte traffic. Nature 392:565.
    • (1998) Nature , vol.392 , pp. 565
    • Baggiolini, M.1
  • 45
    • 0030612473 scopus 로고    scopus 로고
    • An antagonist of monocyte chemoattractant protein-1 (MCP-1) inhibits arthritis in the MRL-lpr mouse model
    • Gong, J., L. G. Ratkay, J. D. Waterfield, and I. Clark-Lewis. 1997. An antagonist of monocyte chemoattractant protein-1 (MCP-1) inhibits arthritis in the MRL-lpr mouse model. J. Exp. Med. 186:131.
    • (1997) J. Exp. Med. , vol.186 , pp. 131
    • Gong, J.1    Ratkay, L.G.2    Waterfield, J.D.3    Clark-Lewis, I.4
  • 46
    • 0027480306 scopus 로고
    • Serum-soluble interleukin-6 receptor in MRL-lpr mice is elevated with age and mediates the interleukin-6 signal
    • Suzuki, H., K. Yasukawa, T. Saito, M. Narazaki, A. Hasegawa, T. Taga, and T. Kishimoto. 1993. Serum-soluble interleukin-6 receptor in MRL-lpr mice is elevated with age and mediates the interleukin-6 signal. Eur. J. Immunol. 23:1078.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 1078
    • Suzuki, H.1    Yasukawa, K.2    Saito, T.3    Narazaki, M.4    Hasegawa, A.5    Taga, T.6    Kishimoto, T.7
  • 48
    • 18344410191 scopus 로고    scopus 로고
    • Blockade of interleukin-6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: Evidence in Crohn disease and experimental colitis in vivo
    • Atreya, R., J. Mudter, S. Finotto, J. Müllberg, T. Jostock, S. Wirtz, M. Schütz, B. Bartsch, M. Holtmann, C. Becker, et al. 2000. Blockade of interleukin-6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: evidence in Crohn disease and experimental colitis in vivo. Nat. Med. 6:583.
    • (2000) Nat. Med. , vol.6 , pp. 583
    • Atreya, R.1    Mudter, J.2    Finotto, S.3    Müllberg, J.4    Jostock, T.5    Wirtz, S.6    Schütz, M.7    Bartsch, B.8    Holtmann, M.9    Becker, C.10
  • 51
    • 0029863504 scopus 로고    scopus 로고
    • The function of the soluble interleukin 6 (IL-6) receptor in vivo: Sensitization of human soluble IL-6 receptor transgenic mice towards IL-6 and prolongation of the plasma half-life of IL-6
    • Peters, M., S. Jacobs, M. Ehlers, P. Vollmer, J. Müllberg, E. Wolf, G. Brem, K.-H.M. zum Büschenfelde, and S. Rose-John. 1996. The function of the soluble interleukin 6 (IL-6) receptor in vivo: sensitization of human soluble IL-6 receptor transgenic mice towards IL-6 and prolongation of the plasma half-life of IL-6. J. Exp. Med. 183:1399.
    • (1996) J. Exp. Med. , vol.183 , pp. 1399
    • Peters, M.1    Jacobs, S.2    Ehlers, M.3    Vollmer, P.4    Müllberg, J.5    Wolf, E.6    Brem, G.7    Zum Büschenfelde, K.-H.M.8    Rose-John, S.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.