-
1
-
-
0028863291
-
The pharmacokinetics of subcutaneously administered recombinant human ciliary neurotrophic factor (rHCNTF) in patients with amyotrophic lateral sclerosis: Relation to parameters of the acute-phase response. The ALS CNTF Treatment Study (ACTS) Phase I-II Study Group
-
ACTS (1995). The pharmacokinetics of subcutaneously administered recombinant human ciliary neurotrophic factor (rHCNTF) in patients with amyotrophic lateral sclerosis: relation to parameters of the acute-phase response. The ALS CNTF Treatment Study (ACTS) Phase I-II Study Group. Clin. Neuropharmacol., 18, 500-514.
-
(1995)
Clin. Neuropharmacol.
, vol.18
, pp. 500-514
-
-
-
2
-
-
0027421831
-
Interleukin-6 in biology and medicine
-
Akira, S., Taga, T. & Kishimoto, T. (1993). Interleukin-6 in biology and medicine. Adv. Immunol., 54, 1-78.
-
(1993)
Adv. Immunol.
, vol.54
, pp. 1-78
-
-
Akira, S.1
Taga, T.2
Kishimoto, T.3
-
3
-
-
0025763298
-
Interleukin-6 and alpha-2-macroglobulin indicate an acute-phase state in Alzheimer's disease cortices
-
Bauer, J., Strauss, S., Schreiter Gasser, U., Ganter, U., Schlegel, P., Witt, I., Yolk, B. & Berger, M. (1991). Interleukin-6 and alpha-2-macroglobulin indicate an acute-phase state in Alzheimer's disease cortices. FEBS Lett., 285, 111-114.
-
(1991)
FEBS Lett.
, vol.285
, pp. 111-114
-
-
Bauer, J.1
Strauss, S.2
Schreiter Gasser, U.3
Ganter, U.4
Schlegel, P.5
Witt, I.6
Yolk, B.7
Berger, M.8
-
4
-
-
0029941260
-
Complex of the soluble IL-11 receptor and IL-11 acts as IL-6-type cytokine in hepatic and nonhepatic cells
-
Baumann, H., Wang, Y., Morella, K.K., Lai, C.F., Dams, H., Hilton, D.J., Hawley, R.G. & Mackiewicz, A. (1996). Complex of the soluble IL-11 receptor and IL-11 acts as IL-6-type cytokine in hepatic and nonhepatic cells. J. Immunol., 157, 284-290.
-
(1996)
J. Immunol.
, vol.157
, pp. 284-290
-
-
Baumann, H.1
Wang, Y.2
Morella, K.K.3
Lai, C.F.4
Dams, H.5
Hilton, D.J.6
Hawley, R.G.7
Mackiewicz, A.8
-
5
-
-
0025102756
-
Haemopoietic receptors and helical cytokines
-
Bazan, J.F. (1990a). Haemopoietic receptors and helical cytokines. Immunol. Today, 11, 350-354.
-
(1990)
Immunol. Today
, vol.11
, pp. 350-354
-
-
Bazan, J.F.1
-
6
-
-
0025162844
-
Structural design and molecular evolution of a cytokine receptor superfamily
-
Bazan, J.F. (1990b). Structural design and molecular evolution of a cytokine receptor superfamily. Proc. Natl Acad. Sci. USA, 87, 6934-6938.
-
(1990)
Proc. Natl Acad. Sci. USA
, vol.87
, pp. 6934-6938
-
-
Bazan, J.F.1
-
7
-
-
0025895320
-
Neuropoietic cytokines in the hematopoietic fold
-
Bazan, J.F. (1991). Neuropoietic cytokines in the hematopoietic fold. Neuron, 7, 197-208.
-
(1991)
Neuron
, vol.7
, pp. 197-208
-
-
Bazan, J.F.1
-
8
-
-
0032539008
-
Postnatally induced inactivation of gp130 in mice results in neurological, cardiac, hematopoietic, immunological, hepatic, and pulmonary defects
-
Betz, U.A.K., Bloch, W., van den Broek, M., Yoshida, K., Taga, T., Kishimoto, T., Addicks, K., Rajewsky, K. & Müller, W. (1998). Postnatally induced inactivation of gp130 in mice results in neurological, cardiac, hematopoietic, immunological, hepatic, and pulmonary defects. J. Exp. Med., 188, 1955-1965.
-
(1998)
J. Exp. Med.
, vol.188
, pp. 1955-1965
-
-
Betz, U.A.K.1
Bloch, W.2
Van Den Broek, M.3
Yoshida, K.4
Taga, T.5
Kishimoto, T.6
Addicks, K.7
Rajewsky, K.8
Müller, W.9
-
9
-
-
0029417080
-
Interleukin-1 beta and interleukin-6 are elevated in the cerebrospinal fluid of Alzheimer's and de novo Parkinson's disease patients
-
Blum-Degen, D., Muller, T., Kuhn, W., Gerlach, M., Przuntek, H. & Riederer, P. (1995). Interleukin-1 beta and interleukin-6 are elevated in the cerebrospinal fluid of Alzheimer's and de novo Parkinson's disease patients. Neurosci. Lett., 202, 17-20.
-
(1995)
Neurosci. Lett.
, vol.202
, pp. 17-20
-
-
Blum-Degen, D.1
Muller, T.2
Kuhn, W.3
Gerlach, M.4
Przuntek, H.5
Riederer, P.6
-
10
-
-
0028873068
-
Interleukin-6 production by Schwann cells and induction in sciatic nerve injury
-
Bolin, L.M., Verity, A.N., Silver, J.E., Shooter, E.M. & Abrams, J.S. (1995). Interleukin-6 production by Schwann cells and induction in sciatic nerve injury. J. Neurochem., 64, 850-858.
-
(1995)
J. Neurochem.
, vol.64
, pp. 850-858
-
-
Bolin, L.M.1
Verity, A.N.2
Silver, J.E.3
Shooter, E.M.4
Abrams, J.S.5
-
11
-
-
0028928520
-
Inflammatory processes induce beta-amyloid precursor protein changes in mouse brain
-
Brugg, B., Dubreuil, Y.L., Huber, G., Wollman, E.E., Delhaye Bouchaud, N. & Mariani, J. (1995). Inflammatory processes induce beta-amyloid precursor protein changes in mouse brain. Proc. Natl Acad. Sci. USA, 92, 3032-3035.
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 3032-3035
-
-
Brugg, B.1
Dubreuil, Y.L.2
Huber, G.3
Wollman, E.E.4
Delhaye Bouchaud, N.5
Mariani, J.6
-
12
-
-
0027433102
-
Neurologic disease induced in transgenic mice by cerebral overexpression of interleukin 6
-
Campbell, I.L., Abraham, C.R., Masliah, E., Kemper, P., Inglis, J.D., Oldstone, M.B. & Mucke, L. (1993). Neurologic disease induced in transgenic mice by cerebral overexpression of interleukin 6. Proc. Natl Acad. Sci. USA, 90, 10061-10065.
-
(1993)
Proc. Natl Acad. Sci. USA
, vol.90
, pp. 10061-10065
-
-
Campbell, I.L.1
Abraham, C.R.2
Masliah, E.3
Kemper, P.4
Inglis, J.D.5
Oldstone, M.B.6
Mucke, L.7
-
13
-
-
0027404834
-
Released form of CNTF receptor alpha component as a soluble mediator of CNTF responses
-
Davis, S., Aldrich, T.H., Ip, N.Y., Stahl, N., Scherer, S., Farruggella, T., DiStefano, P.S., Curtis, R., Panayotatos, N., Gascan, H., Chevalier, S. & Yancopulos, G.D. (1993). Released form of CNTF receptor alpha component as a soluble mediator of CNTF responses. Science, 259, 1736-1739.
-
(1993)
Science
, vol.259
, pp. 1736-1739
-
-
Davis, S.1
Aldrich, T.H.2
Ip, N.Y.3
Stahl, N.4
Scherer, S.5
Farruggella, T.6
DiStefano, P.S.7
Curtis, R.8
Panayotatos, N.9
Gascan, H.10
Chevalier, S.11
Yancopulos, G.D.12
-
14
-
-
0028788476
-
Mice lacking the CNTF receptor, unlike mice lacking CNTF, exhibit profound motor neuron deficits at birth
-
DeChiara, T.M., Vejsada, R., Poueymirou, W.T., Acheson, A., Suri, C., Conover, J.C., Friedman, B., McClain, J., Pan, L., Stahl, N. &. et al. (1995). Mice lacking the CNTF receptor, unlike mice lacking CNTF, exhibit profound motor neuron deficits at birth. Cell, 83, 313-322.
-
(1995)
Cell
, vol.83
, pp. 313-322
-
-
DeChiara, T.M.1
Vejsada, R.2
Poueymirou, W.T.3
Acheson, A.4
Suri, C.5
Conover, J.C.6
Friedman, B.7
McClain, J.8
Pan, L.9
Stahl, N.10
-
15
-
-
0027233526
-
Leukaemia inhibitory factor is necessary for maintenance of haematopoietic stem cells and thymocyte stimulation
-
Escary, J.L., Perreau, J., Dumenil, D., Ezine, S. & Brulet, P. (1993). Leukaemia inhibitory factor is necessary for maintenance of haematopoietic stem cells and thymocyte stimulation. Nature, 363, 361-364.
-
(1993)
Nature
, vol.363
, pp. 361-364
-
-
Escary, J.L.1
Perreau, J.2
Dumenil, D.3
Ezine, S.4
Brulet, P.5
-
16
-
-
0027982943
-
Neuropoietic cytokines and activin a differentially regulate the phenotype of cultured sympathetic neurons
-
Fann, M.J. & Patterson, P.H. (1994). Neuropoietic cytokines and activin A differentially regulate the phenotype of cultured sympathetic neurons. Proc. Natl Acad. Sci. USA, 91, 43-47.
-
(1994)
Proc. Natl Acad. Sci. USA
, vol.91
, pp. 43-47
-
-
Fann, M.J.1
Patterson, P.H.2
-
17
-
-
0030614539
-
A designer cytokine with high activity on human hematopoietic progenitor cells
-
Fischer, M., Goldschmitt, J., Peschel, C., Kallen, K.J., Brakenhoff, J.P.J., Wollmer, A., Grötzinger, J. & Rose-John, S. (1997). A designer cytokine with high activity on human hematopoietic progenitor cells. Nature Biotech., 15, 142-145.
-
(1997)
Nature Biotech.
, vol.15
, pp. 142-145
-
-
Fischer, M.1
Goldschmitt, J.2
Peschel, C.3
Kallen, K.J.4
Brakenhoff, J.P.J.5
Wollmer, A.6
Grötzinger, J.7
Rose-John, S.8
-
18
-
-
0031081117
-
CNTF and LIF are not required for the target-directed acquisition of cholinergic and peptidergic properties by sympathetic neurons in vivo
-
Francis, N.J., Asmus, S.E. & Landis, S.C. (1997). CNTF and LIF are not required for the target-directed acquisition of cholinergic and peptidergic properties by sympathetic neurons in vivo. Dev. Biol., 182, 76-87.
-
(1997)
Dev. Biol.
, vol.182
, pp. 76-87
-
-
Francis, N.J.1
Asmus, S.E.2
Landis, S.C.3
-
19
-
-
0028128936
-
Soluble interleukin 6 receptor in biological fluids from human origin
-
Frieling, J.T., Sauerwein, R.W., Wijdenes, J., Hendriks, T. & van der Linden, C.J. (1994). Soluble interleukin 6 receptor in biological fluids from human origin. Cytokine, 6, 376-381.
-
(1994)
Cytokine
, vol.6
, pp. 376-381
-
-
Frieling, J.T.1
Sauerwein, R.W.2
Wijdenes, J.3
Hendriks, T.4
Van Der Linden, C.J.5
-
20
-
-
0027309536
-
Differential expression of interleukin-6 (IL-6) and interleukin-6 receptor (IL-6R) mRNAs in rat hypothalamus
-
Gadient, R.A. & Otten, U. (1993). Differential expression of interleukin-6 (IL-6) and interleukin-6 receptor (IL-6R) mRNAs in rat hypothalamus. Neurosci. Lett., 153, 13-16.
-
(1993)
Neurosci. Lett.
, vol.153
, pp. 13-16
-
-
Gadient, R.A.1
Otten, U.2
-
21
-
-
0028069262
-
Expression of interleukin-6 (IL-6) and interleukin-6 receptor (IL-6R) mRNAs in rat brain during postnatal development
-
Gadient, R.A. & Otten, U. (1994). Expression of interleukin-6 (IL-6) and interleukin-6 receptor (IL-6R) mRNAs in rat brain during postnatal development. Brain Res., 637, 10-14.
-
(1994)
Brain Res.
, vol.637
, pp. 10-14
-
-
Gadient, R.A.1
Otten, U.2
-
22
-
-
0029895740
-
Postnatal expression of interleukin-6 (IL-6) and IL-6 receptor (IL-6R) mRNAs in rat sympathetic and sensory ganglia
-
Gadient, R.A. & Otten, U. (1996). Postnatal expression of interleukin-6 (IL-6) and IL-6 receptor (IL-6R) mRNAs in rat sympathetic and sensory ganglia. Brain Res., 724, 41-46.
-
(1996)
Brain Res.
, vol.724
, pp. 41-46
-
-
Gadient, R.A.1
Otten, U.2
-
23
-
-
2442690993
-
Molecular cloning and expression of cDNA encoding a murine myeloid leukaemia inhibitory factor (LIF)
-
Gearing, D.P., Gough, N.M., King, J.A., Hilton, D.J., Nicola, N.A., Simpson, R.J., Nice, E.C., Kelso, A. & Metcalf, D. (1987). Molecular cloning and expression of cDNA encoding a murine myeloid leukaemia inhibitory factor (LIF). EMBO J., 6, 3995-4002.
-
(1987)
EMBO J.
, vol.6
, pp. 3995-4002
-
-
Gearing, D.P.1
Gough, N.M.2
King, J.A.3
Hilton, D.J.4
Nicola, N.A.5
Simpson, R.J.6
Nice, E.C.7
Kelso, A.8
Metcalf, D.9
-
24
-
-
0032414393
-
The specification of sympathetic neurotransmitter phenotype depends on gp130 cytokine receptor signaling
-
Geissen, M., Heller, S., Pennica, D., Ernsberger, U. & Rohrer, H. (1998). The specification of sympathetic neurotransmitter phenotype depends on gp130 cytokine receptor signaling. Development, 125, 4791-4801.
-
(1998)
Development
, vol.125
, pp. 4791-4801
-
-
Geissen, M.1
Heller, S.2
Pennica, D.3
Ernsberger, U.4
Rohrer, H.5
-
25
-
-
0023545249
-
PC12 pheochromocytoma cells: Culture, nerve growth factor treatment, and experimental exploitation
-
Greene, L.A., Aletta, J.M., Rukenstein, A. & Green, S.H. (1987). PC12 pheochromocytoma cells: culture, nerve growth factor treatment, and experimental exploitation. Meth. Enzymol., 147, 207-216.
-
(1987)
Meth. Enzymol.
, vol.147
, pp. 207-216
-
-
Greene, L.A.1
Aletta, J.M.2
Rukenstein, A.3
Green, S.H.4
-
26
-
-
0345704610
-
Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor
-
Greene, L.A. & Tischler, A.S. (1976). Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc. Natl Acad. Sci. USA, 73, 2424-2428.
-
(1976)
Proc. Natl Acad. Sci. USA
, vol.73
, pp. 2424-2428
-
-
Greene, L.A.1
Tischler, A.S.2
-
27
-
-
0037987019
-
The family of the IL-6-type cytokines: Specificity and promiscuity of the receptor complexes
-
Grötzinger, J., Kurapkat, G., Wollmer, A., Kalai, M. & Rose-John, S. (1997). The family of the IL-6-type cytokines: specificity and promiscuity of the receptor complexes. Proteins Structure, Function Genet., 27, 96-109.
-
(1997)
Proteins Structure, Function Genet.
, vol.27
, pp. 96-109
-
-
Grötzinger, J.1
Kurapkat, G.2
Wollmer, A.3
Kalai, M.4
Rose-John, S.5
-
28
-
-
0031301027
-
Physiological and pathological roles of interleukin-6 in the central nervous system
-
Gruol, D.L. & Nelson, T.E. (1997). Physiological and pathological roles of interleukin-6 in the central nervous system. Mol. Neurobiol., 15, 307-339.
-
(1997)
Mol. Neurobiol.
, vol.15
, pp. 307-339
-
-
Gruol, D.L.1
Nelson, T.E.2
-
29
-
-
0030730936
-
A sweat gland-derived differentiation activity acts through known cytokine signaling pathways
-
Habecker, B.A., Symes, A.J., Stahl, N., Francis, N.J., Economides, A., Fink, J.S., Yancopoulos, G.D. & Landis, S.C. (1997). A sweat gland-derived differentiation activity acts through known cytokine signaling pathways. J. Biol. Chem., 272, 30421-30428.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 30421-30428
-
-
Habecker, B.A.1
Symes, A.J.2
Stahl, N.3
Francis, N.J.4
Economides, A.5
Fink, J.S.6
Yancopoulos, G.D.7
Landis, S.C.8
-
30
-
-
17644439518
-
Interleukin-6 is not altered in cerebrospinal fluid of first-degree relatives and patients with Alzheimer's disease
-
Hampel, H., Schoen, D., Schwarz, M.J., Kotter, H.U., Schneider, C., Sunderland, T., Dukoff, R., Levy, J., Padberg, F., Stubner, S., Buch, K., Muller, N. & Moller, H.J. (1998). Interleukin-6 is not altered in cerebrospinal fluid of first-degree relatives and patients with Alzheimer's disease. Neurosci. Lett., 228, 143-146.
-
(1998)
Neurosci. Lett.
, vol.228
, pp. 143-146
-
-
Hampel, H.1
Schoen, D.2
Schwarz, M.J.3
Kotter, H.U.4
Schneider, C.5
Sunderland, T.6
Dukoff, R.7
Levy, J.8
Padberg, F.9
Stubner, S.10
Buch, K.11
Muller, N.12
Moller, H.J.13
-
31
-
-
0025630163
-
Molecular cloning and expression of an IL-6 signal transducer, gp130
-
Hibi, M., Murakami, M., Saito, M., Hirano, T., Taga, T. & Kishimoto, T. (1990). Molecular cloning and expression of an IL-6 signal transducer, gp130. Cell, 63, 1149-1157.
-
(1990)
Cell
, vol.63
, pp. 1149-1157
-
-
Hibi, M.1
Murakami, M.2
Saito, M.3
Hirano, T.4
Taga, T.5
Kishimoto, T.6
-
32
-
-
0031429943
-
Signaling mechanisms through gp130: A model of the cytokine system
-
Hirano, T., Nakajima, K. & Hibi, M. (1997). Signaling mechanisms through gp130: a model of the cytokine system. Cytokine Growth Factor Rev., 4, 241-252.
-
(1997)
Cytokine Growth Factor Rev.
, vol.4
, pp. 241-252
-
-
Hirano, T.1
Nakajima, K.2
Hibi, M.3
-
33
-
-
0029894833
-
Accelerated Nerve Regeneration in Mice by upregulated expression of interleukin (IL) 6 and IL-6 receptor after trauma
-
Hirota, H., Kiyama, H., Kishimoto, T. & Taga, T. (1996). Accelerated Nerve Regeneration in Mice by upregulated expression of interleukin (IL) 6 and IL-6 receptor after trauma. J. Exp. Med., 183, 2627-2634.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 2627-2634
-
-
Hirota, H.1
Kiyama, H.2
Kishimoto, T.3
Taga, T.4
-
34
-
-
0028800715
-
Cytokines and the nervous system I: Expression and recognition
-
Hopkins, S.J. & Rothwell, N.J. (1995). Cytokines and the nervous system I: expression and recognition. Trends Neurosci., 18, 83-88.
-
(1995)
Trends Neurosci.
, vol.18
, pp. 83-88
-
-
Hopkins, S.J.1
Rothwell, N.J.2
-
35
-
-
0030014561
-
The participation of interleukin-6, a stress-inducible cytokine, in the pathogenesis of Alzheimer's diseas patients
-
Hüll, M., Strauss, S., Berger, M., Volk, B. & Bauer, J. (1996). The participation of interleukin-6, a stress-inducible cytokine, in the pathogenesis of Alzheimer's diseas patients. Behav. Brain Res., 78, 37-41.
-
(1996)
Behav. Brain Res.
, vol.78
, pp. 37-41
-
-
Hüll, M.1
Strauss, S.2
Berger, M.3
Volk, B.4
Bauer, J.5
-
36
-
-
0029051259
-
Interleukin-6 is present at early stages of plaques formation and is restricted to the brains of Alzheimer's disease patients
-
Hüll, M., Strauss, S., Volk, B., Berger, M. & Bauer, J. (1995). Interleukin-6 is present at early stages of plaques formation and is restricted to the brains of Alzheimer's disease patients. Acta Neuropathol., 89, 544-551.
-
(1995)
Acta Neuropathol.
, vol.89
, pp. 544-551
-
-
Hüll, M.1
Strauss, S.2
Volk, B.3
Berger, M.4
Bauer, J.5
-
37
-
-
0030030679
-
Neuroprotective effect of various cytokines on developing spinal motoneurons following axotomy
-
Ikeda, K., Iwasaki, Y., Shiojima, T. & Kinoshita, M. (1996a). Neuroprotective effect of various cytokines on developing spinal motoneurons following axotomy. J. Neurol. Sci., 135, 109-113.
-
(1996)
J. Neurol. Sci.
, vol.135
, pp. 109-113
-
-
Ikeda, K.1
Iwasaki, Y.2
Shiojima, T.3
Kinoshita, M.4
-
38
-
-
0030575293
-
Coadministration of interleukin-6 (IL-6) and soluble IL-6 receptor delays progression of wobbler mouse motor neuron disease
-
Ikeda, K., Kinoshita, M., Tagaya, N., Shiojima, T., Taga, T., Yasukawa, K., Suzuki, H. & Okano, A. (1996b). Coadministration of interleukin-6 (IL-6) and soluble IL-6 receptor delays progression of wobbler mouse motor neuron disease. Brain Res., 726, 91-97.
-
(1996)
Brain Res.
, vol.726
, pp. 91-97
-
-
Ikeda, K.1
Kinoshita, M.2
Tagaya, N.3
Shiojima, T.4
Taga, T.5
Yasukawa, K.6
Suzuki, H.7
Okano, A.8
-
39
-
-
0032543111
-
Differential temporal expression of mRNAs for ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), interleukin-6 (IL-6), and their receptors (CNTFR alpha, LIFR beta, IL-6R alpha and gp130) in injured peripheral nerves
-
Ito, Y., Yamamoto, M., Li, M., Doyu, M., Tanaka, F., Mutch, T., Mitsuma, T. & Sobue, G. (1998). Differential temporal expression of mRNAs for ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), interleukin-6 (IL-6), and their receptors (CNTFR alpha, LIFR beta, IL-6R alpha and gp130) in injured peripheral nerves. Brain Res., 793, 321-327.
-
(1998)
Brain Res.
, vol.793
, pp. 321-327
-
-
Ito, Y.1
Yamamoto, M.2
Li, M.3
Doyu, M.4
Tanaka, F.5
Mutch, T.6
Mitsuma, T.7
Sobue, G.8
-
40
-
-
0030941553
-
The therapeutic potential of interleukin-6 hyperagonists and antagonists
-
Kallen, K.-J., Meyer zum Büschenfelde, K.H. & Rose-John, S. (1997). The therapeutic potential of interleukin-6 hyperagonists and antagonists. Exp. Opin. Invest. Drugs, 6, 237-266.
-
(1997)
Exp. Opin. Invest. Drugs
, vol.6
, pp. 237-266
-
-
Kallen, K.-J.1
Meyer Zum Büschenfelde, K.H.2
Rose-John, S.3
-
41
-
-
0030855888
-
Serum interleukin-6 levels correlate with the severity of dementia in Down syndrome and in Alzheimer disease
-
Kalman, J., Juhasz, A., Laird, G., Dickens, P., Jardanhazy, T., Rimanoczy, A., Boncz, I., Parry-Jones, W.L.I. & Janka, Z. (1997). Serum interleukin-6 levels correlate with the severity of dementia in Down syndrome and in Alzheimer disease. Acta Neurol. Scand., 96, 236-240.
-
(1997)
Acta Neurol. Scand.
, vol.96
, pp. 236-240
-
-
Kalman, J.1
Juhasz, A.2
Laird, G.3
Dickens, P.4
Jardanhazy, T.5
Rimanoczy, A.6
Boncz, I.7
Parry-Jones, W.L.I.8
Janka, Z.9
-
42
-
-
0027236367
-
Interleukin-6 and transforming growth factor-beta 1 mRNAs are induced in rat facial nucleus following motoneuron axotomy
-
Kiefer, R., Lindholm, D. & Kreutzberg, G.W. (1993). Interleukin-6 and transforming growth factor-beta 1 mRNAs are induced in rat facial nucleus following motoneuron axotomy. Eur. J. Neurosci, 5, 775-781.
-
(1993)
Eur. J. Neurosci
, vol.5
, pp. 775-781
-
-
Kiefer, R.1
Lindholm, D.2
Kreutzberg, G.W.3
-
43
-
-
0031104861
-
Impaired neuroglial activation in interleukin-6 deficient mice
-
Klein, M.A., Moller, J.C., Jones, L.L., Bluethmann, H., Kreutzberg, G.W. & Raivich, G. (1997). Impaired neuroglial activation in interleukin-6 deficient mice. Glia, 19, 227-233.
-
(1997)
Glia
, vol.19
, pp. 227-233
-
-
Klein, M.A.1
Moller, J.C.2
Jones, L.L.3
Bluethmann, H.4
Kreutzberg, G.W.5
Raivich, G.6
-
44
-
-
0028328436
-
Impaired immune and acute-phase responses in interleukin-6-deficient mice
-
Kopf, M., Baumann, H., Freer, G., Freudenberg, M., Lamers, M., Kishimoto, T., Zinkernagel, R., Bluethmann, H. & Kohler, G. (1994). Impaired immune and acute-phase responses in interleukin-6-deficient mice. Nature, 368, 339-342.
-
(1994)
Nature
, vol.368
, pp. 339-342
-
-
Kopf, M.1
Baumann, H.2
Freer, G.3
Freudenberg, M.4
Lamers, M.5
Kishimoto, T.6
Zinkernagel, R.7
Bluethmann, H.8
Kohler, G.9
-
45
-
-
0028059070
-
Development of sympathetic neurons: Neurotransmitter plasticity and differentiation factors
-
Landis, S.C. (1994). Development of sympathetic neurons: neurotransmitter plasticity and differentiation factors. Prog. Brain Res., 100, 19-23.
-
(1994)
Prog. Brain Res.
, vol.100
, pp. 19-23
-
-
Landis, S.C.1
-
46
-
-
0026775147
-
A major binding protein for leukemia inhibitory factor in normal mouse serum: Identification as a soluble form of the cellular receptor
-
Layton, M.J., Cross, B.A., Metcalf, D., Ward, L.D., Simpson, R.J. & Nicola, N.A. (1992). A major binding protein for leukemia inhibitory factor in normal mouse serum: identification as a soluble form of the cellular receptor. Proc. Natl Acad. Sci. USA, 89, 8616-8620.
-
(1992)
Proc. Natl Acad. Sci. USA
, vol.89
, pp. 8616-8620
-
-
Layton, M.J.1
Cross, B.A.2
Metcalf, D.3
Ward, L.D.4
Simpson, R.J.5
Nicola, N.A.6
-
47
-
-
0029620955
-
Essential function of LIF receptor in motor neurons
-
Li, M., Sendtner, M. & Smith, A. (1995). Essential function of LIF receptor in motor neurons. Nature, 378, 724-727.
-
(1995)
Nature
, vol.378
, pp. 724-727
-
-
Li, M.1
Sendtner, M.2
Smith, A.3
-
48
-
-
0026828552
-
Isolation of an mRNA encoding a soluble form of the human interleukin-6 receptor
-
Lust, J.A., Donovan, K.A., Kline, M.P., Greipp, P.R., Kyle, R.A. & Maihle, N.J. (1992). Isolation of an mRNA encoding a soluble form of the human interleukin-6 receptor. Cytokine, 4, 96-100.
-
(1992)
Cytokine
, vol.4
, pp. 96-100
-
-
Lust, J.A.1
Donovan, K.A.2
Kline, M.P.3
Greipp, P.R.4
Kyle, R.A.5
Maihle, N.J.6
-
49
-
-
0028035051
-
Sequence, expression and function of an mRNA encoding a soluble form of the human interleukin-6 receptor (sIL-6R)
-
Lust, J.A., Jelinek, D.F., Donovan, K.A., Frederick, L.A., Huntley, B.K., Braaten, J.K. & Maihle, N.J. (1995). Sequence, expression and function of an mRNA encoding a soluble form of the human interleukin-6 receptor (sIL-6R). Curr. Top. Microbiol. Immunol., 194, 199-206.
-
(1995)
Curr. Top. Microbiol. Immunol.
, vol.194
, pp. 199-206
-
-
Lust, J.A.1
Jelinek, D.F.2
Donovan, K.A.3
Frederick, L.A.4
Huntley, B.K.5
Braaten, J.K.6
Maihle, N.J.7
-
50
-
-
0032539893
-
Sympathetic neurons can produce and respond to Interleukin-6
-
März, P., Cheng, J.-C., Gadient, R.A., Patterson, P., Stoyan, T., Otten, U. & Rose-John, S. (1998). Sympathetic neurons can produce and respond to Interleukin-6. Proc. Natl Acad. Sci. USA, 95, 3251-3256.
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 3251-3256
-
-
März, P.1
Cheng, J.-C.2
Gadient, R.A.3
Patterson, P.4
Stoyan, T.5
Otten, U.6
Rose-John, S.7
-
51
-
-
0343773463
-
Expression of interleukin-6 receptor (IL-6R) and gp130 mRNA in PC12 cells and sympathetic neurons: Modulation by tumor necrosis factor alpha (TNF-alpha)
-
März, P., Gadient, R.A. & Otten, U. (1996). Expression of interleukin-6 receptor (IL-6R) and gp130 mRNA in PC12 cells and sympathetic neurons: modulation by tumor necrosis factor alpha (TNF-alpha). Brain Res., 706, 71-79.
-
(1996)
Brain Res.
, vol.706
, pp. 71-79
-
-
März, P.1
Gadient, R.A.2
Otten, U.3
-
52
-
-
0345104338
-
Role of interleukin-6 and soluble IL-6 receptor in region specific induction of astrocytic differentiation and neurotrophin expression
-
März, P., Heese, K., Dimitriades-Schmutz, B., Rose-John, S. & Otten, U. (1999). Role of interleukin-6 and soluble IL-6 receptor in region specific induction of astrocytic differentiation and neurotrophin expression. Glia, 26, 191-200.
-
(1999)
Glia
, vol.26
, pp. 191-200
-
-
März, P.1
Heese, K.2
Dimitriades-Schmutz, B.3
Rose-John, S.4
Otten, U.5
-
53
-
-
0344333426
-
Interleukin-6 (IL-6) and soluble forms of IL-6 receptors are not altered in cerebrospinal fluid of Alzheimer's disease patients
-
März, P., Heese, K., Hock, C., Golombowski, S., Müller-Spahn, F., Rose-John, S. & Otten, U. (1997a). Interleukin-6 (IL-6) and soluble forms of IL-6 receptors are not altered in cerebrospinal fluid of Alzheimer's disease patients. Neurosci. Lett., 239, 29-32.
-
(1997)
Neurosci. Lett.
, vol.239
, pp. 29-32
-
-
März, P.1
Heese, K.2
Hock, C.3
Golombowski, S.4
Müller-Spahn, F.5
Rose-John, S.6
Otten, U.7
-
54
-
-
0031410622
-
Activation of gp130 by IL-6/soluble IL-6 Receptor Induces Neuronal Differentiation
-
März, P., Herget, T., Lang, E., Otten, U. & Rose-John, S. (1997b). Activation of gp130 by IL-6/soluble IL-6 Receptor Induces Neuronal Differentiation. Eur. J. Neurosci., 9, 2765-2773.
-
(1997)
Eur. J. Neurosci.
, vol.9
, pp. 2765-2773
-
-
März, P.1
Herget, T.2
Lang, E.3
Otten, U.4
Rose-John, S.5
-
55
-
-
0027484249
-
Disruption of the CNTF gene results in motor neuron degeneration
-
Masu, Y., Wolf, E., Holtmann, B., Sendtner, M., Brem, G. & Thoenen, H. (1993). Disruption of the CNTF gene results in motor neuron degeneration. Nature, 365, 27-32.
-
(1993)
Nature
, vol.365
, pp. 27-32
-
-
Masu, Y.1
Wolf, E.2
Holtmann, B.3
Sendtner, M.4
Brem, G.5
Thoenen, H.6
-
56
-
-
0029610011
-
The inflammatory response of the brain: Implications for therapy of Alzheimer and other neurodegenerative diseases
-
McGeer, P.L. & McGeer, E.G. (1995). The inflammatory response of the brain: implications for therapy of Alzheimer and other neurodegenerative diseases. Brain Res. Rev., 21, 195-218.
-
(1995)
Brain Res. Rev.
, vol.21
, pp. 195-218
-
-
McGeer, P.L.1
McGeer, E.G.2
-
57
-
-
0030859106
-
Hematolymphopoietic and inflammatory cytokines in neuronal development
-
Mehler, M.F. & Kessler, J.A. (1997). Hematolymphopoietic and inflammatory cytokines in neuronal development. Trends Neurosci., 20, 357-365.
-
(1997)
Trends Neurosci.
, vol.20
, pp. 357-365
-
-
Mehler, M.F.1
Kessler, J.A.2
-
58
-
-
0031471861
-
Retrograde inflammatory signaling from neutrophils to endothelial cells by soluble interleukin-6 receptor alpha
-
Modur, V., Li, Y., Zimmerman, G.A., Prescott, S.M. & McIntyre, T.M. (1997). Retrograde inflammatory signaling from neutrophils to endothelial cells by soluble interleukin-6 receptor alpha. J. Clin. Invest, 100, 2752-2756.
-
(1997)
J. Clin. Invest
, vol.100
, pp. 2752-2756
-
-
Modur, V.1
Li, Y.2
Zimmerman, G.A.3
Prescott, S.M.4
McIntyre, T.M.5
-
59
-
-
0024210526
-
Leukaemia inhibitory factor is identical to the myeloid growth factor human interleukin for DA cells
-
Moreau, J.F., Donaldson, D.D., Bennett, F., Witek Giannotti, J., Clark, S.C. & Wong, G.G. (1988). Leukaemia inhibitory factor is identical to the myeloid growth factor human interleukin for DA cells. Nature, 336, 690-692.
-
(1988)
Nature
, vol.336
, pp. 690-692
-
-
Moreau, J.F.1
Donaldson, D.D.2
Bennett, F.3
Witek Giannotti, J.4
Clark, S.C.5
Wong, G.G.6
-
60
-
-
12644294970
-
Dual oncostatin M (OSM) receptors. Cloning and characterization of an alternative signaling subunit conferring OSM-specific receptor activation
-
Mosley, B., De Imus, C., Friend, D., Boiani, N., Thoma, B., Park, L.S. & Cosman, D. (1996). Dual oncostatin M (OSM) receptors. Cloning and characterization of an alternative signaling subunit conferring OSM-specific receptor activation. J. Biol. Chem., 271, 32635-32643.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 32635-32643
-
-
Mosley, B.1
De Imus, C.2
Friend, D.3
Boiani, N.4
Thoma, B.5
Park, L.S.6
Cosman, D.7
-
61
-
-
0027398766
-
The soluble interleukin-6 receptor is generated by shedding
-
Müllberg, J., Schooltink, H., Stoyan, T., Gunther, M., Graeve, L., Buse, G., Mackiewicz, A., Heinrich, P.C. & Rose-John, S. (1993). The soluble interleukin-6 receptor is generated by shedding. Eur. J. Immunol., 23, 473-480.
-
(1993)
Eur. J. Immunol.
, vol.23
, pp. 473-480
-
-
Müllberg, J.1
Schooltink, H.2
Stoyan, T.3
Gunther, M.4
Graeve, L.5
Buse, G.6
Mackiewicz, A.7
Heinrich, P.C.8
Rose-John, S.9
-
62
-
-
0038739858
-
Soluble IL-6 receptor potentiates the antagonistic activity of soluble gp130 on IL-6 responses
-
Müller-Newen, G., Küster, A., Hemmann, U., Keul, R., Horsten, U., Martens, A., Graeve, L., Wijdenes, J. & Heinrich, P.C. (1998). Soluble IL-6 receptor potentiates the antagonistic activity of soluble gp130 on IL-6 responses. J. Immunol., 161, 6347-6355.
-
(1998)
J. Immunol.
, vol.161
, pp. 6347-6355
-
-
Müller-Newen, G.1
Küster, A.2
Hemmann, U.3
Keul, R.4
Horsten, U.5
Martens, A.6
Graeve, L.7
Wijdenes, J.8
Heinrich, P.C.9
-
63
-
-
0030847329
-
Adult mice with targeted mutation of the interleukin-11 receptor (IL11Ra) display normal hematopoiesis
-
Nandurkar, H.H., Robb, L., Tarlinton, D., Barnett, L., Kontgen, F. & Begley, C.G. (1997). Adult mice with targeted mutation of the interleukin-11 receptor (IL11Ra) display normal hematopoiesis. Blood, 90, 2148-2159.
-
(1997)
Blood
, vol.90
, pp. 2148-2159
-
-
Nandurkar, H.H.1
Robb, L.2
Tarlinton, D.3
Barnett, L.4
Kontgen, F.5
Begley, C.G.6
-
64
-
-
0027293104
-
Soluble forms of the interleukin-6 signal-transducing receptor component gp130 in human serum possessing a potential to inhibit signals through membrane-anchored gp130
-
Narazaki, M., Yasukawa, K., Saito, T., Ohsugi, Y., Fukui, H., Koishihara, Y., Yancopoulos, G.D., Taga, T. & Kishimoto, T. (1993). Soluble forms of the interleukin-6 signal-transducing receptor component gp130 in human serum possessing a potential to inhibit signals through membrane-anchored gp130. Blood, 82, 1120-1126.
-
(1993)
Blood
, vol.82
, pp. 1120-1126
-
-
Narazaki, M.1
Yasukawa, K.2
Saito, T.3
Ohsugi, Y.4
Fukui, H.5
Koishihara, Y.6
Yancopoulos, G.D.7
Taga, T.8
Kishimoto, T.9
-
65
-
-
0026618659
-
Soluble interferon-alpha receptor molecules are present in body fluids
-
Novick, D., Cohen, B. & Rubinstein, M. (1992). Soluble interferon-alpha receptor molecules are present in body fluids. FEBS Lett., 314, 445-448.
-
(1992)
FEBS Lett.
, vol.314
, pp. 445-448
-
-
Novick, D.1
Cohen, B.2
Rubinstein, M.3
-
66
-
-
0024458160
-
Soluble cytokine receptors are present in normal human urine
-
Novick, D., Engelmann, H., Wallach, D. & Rubinstein, M. (1989). Soluble cytokine receptors are present in normal human urine. J. Exp. Med., 170, 1409-1414.
-
(1989)
J. Exp. Med.
, vol.170
, pp. 1409-1414
-
-
Novick, D.1
Engelmann, H.2
Wallach, D.3
Rubinstein, M.4
-
67
-
-
0032212261
-
Role of IL-6 and the Soluble IL-6 Receptor in Inhibition of VCAM-1 Gene Expression
-
Oh, J.-W., van Wagoner, N., Rose-John, S. & Benveniste, E.N. (1998). Role of IL-6 and the Soluble IL-6 Receptor in Inhibition of VCAM-1 Gene Expression. J. Immunol., 161, 4992-4999.
-
(1998)
J. Immunol.
, vol.161
, pp. 4992-4999
-
-
Oh, J.-W.1
Van Wagoner, N.2
Rose-John, S.3
Benveniste, E.N.4
-
68
-
-
15844394982
-
Cardiotrophin-1, a cytokine present in embryonic muscle, supports long-term survival of spinal motoneurons
-
Pennica, D., Arce, V., Swanson, T.A., Vejsada, R., Pollock, R.A., Armanini, M., Dudley, K., Phillips, H.S., Rosenthal, A., Kato, A.C. & Henderson, C.E. (1996a). Cardiotrophin-1, a cytokine present in embryonic muscle, supports long-term survival of spinal motoneurons. Neuron, 17, 63-74.
-
(1996)
Neuron
, vol.17
, pp. 63-74
-
-
Pennica, D.1
Arce, V.2
Swanson, T.A.3
Vejsada, R.4
Pollock, R.A.5
Armanini, M.6
Dudley, K.7
Phillips, H.S.8
Rosenthal, A.9
Kato, A.C.10
Henderson, C.E.11
-
69
-
-
0030183049
-
Cardiotrophin-1: A multifunctional cytokine that signals via LIF receptor-gp 130 dependent pathways
-
Pennica, D., Wood, W.I. & Chien, K.R. (1996b). Cardiotrophin-1: a multifunctional cytokine that signals via LIF receptor-gp 130 dependent pathways. Cytokine Growth Factor Rev., 7, 81-91.
-
(1996)
Cytokine Growth Factor Rev.
, vol.7
, pp. 81-91
-
-
Pennica, D.1
Wood, W.I.2
Chien, K.R.3
-
70
-
-
0031201133
-
Soluble IL-6 Receptor leads to a paracrine modulation of the hepatic acute phase response in double transgenic mice
-
Peters, M., Odenthal, M., Schirmacher, P., Blessing, M., Ciliberto, G., Meyer zum Büschenfelde, K.H. & Rose-John, S. (1997a). Soluble IL-6 Receptor leads to a paracrine modulation of the hepatic acute phase response in double transgenic mice. J. Immunol., 159, 1474-1481.
-
(1997)
J. Immunol.
, vol.159
, pp. 1474-1481
-
-
Peters, M.1
Odenthal, M.2
Schirmacher, P.3
Blessing, M.4
Ciliberto, G.5
Meyer Zum Büschenfelde, K.H.6
Rose-John, S.7
-
71
-
-
18244419398
-
Extramedullary expansion of hematopoietic progenitor cells in IL-6/sIL-6R double transgenic mice
-
Peters, M., Schirmacher, P., Goldschmitt, J., Odenthal, M., Peschel, C., Dienes, H.P., Fattori, E., Ciliberto, G., Meyer zum Büschenfelde, K.H. & Rose-John, S. (1997b). Extramedullary expansion of hematopoietic progenitor cells in IL-6/sIL-6R double transgenic mice. J. Exp. Med., 185, 755-766.
-
(1997)
J. Exp. Med.
, vol.185
, pp. 755-766
-
-
Peters, M.1
Schirmacher, P.2
Goldschmitt, J.3
Odenthal, M.4
Peschel, C.5
Dienes, H.P.6
Fattori, E.7
Ciliberto, G.8
Meyer Zum Büschenfelde, K.H.9
Rose-John, S.10
-
72
-
-
0032579752
-
Enhancement of beta-amyloid precursor protein transcription and expression by the soluble interleukin-6 receptor/ interleukin-6 complex
-
Ringheim, G.E., Szczepanik, A.M., Petko, W., Burgher, K.L., Zhu, S.Z. & Chao, C.C. (1998). Enhancement of beta-amyloid precursor protein transcription and expression by the soluble interleukin-6 receptor/ interleukin-6 complex. Brain Res. Mol. Brain Res., 55, 35-44.
-
(1998)
Brain Res. Mol. Brain Res.
, vol.55
, pp. 35-44
-
-
Ringheim, G.E.1
Szczepanik, A.M.2
Petko, W.3
Burgher, K.L.4
Zhu, S.Z.5
Chao, C.C.6
-
73
-
-
0030891228
-
Role of IL-6 and its soluble receptor in induction of chemokines and leukocyte recruitment
-
Romano, M., Sironi, M., Toniatti, C., Polentarutti, N., Fruscella, P., Ghezzi, P., Faggioni, R., Luini, W., van Hinsbergh, V., Sozzani, S., Bussolino, F., Poli, V., Ciliberto, G. & Mantovani, A. (1997). Role of IL-6 and its soluble receptor in induction of chemokines and leukocyte recruitment. Immunity, 6, 315-325.
-
(1997)
Immunity
, vol.6
, pp. 315-325
-
-
Romano, M.1
Sironi, M.2
Toniatti, C.3
Polentarutti, N.4
Fruscella, P.5
Ghezzi, P.6
Faggioni, R.7
Luini, W.8
Van Hinsbergh, V.9
Sozzani, S.10
Bussolino, F.11
Poli, V.12
Ciliberto, G.13
Mantovani, A.14
-
74
-
-
0028226196
-
Soluble receptors for cytokines and growth factors: Generation and biological function
-
Rose-John, S. & Heinrich, P.C. (1994). Soluble receptors for cytokines and growth factors: generation and biological function. Biochem. J., 300, 281-290.
-
(1994)
Biochem. J.
, vol.300
, pp. 281-290
-
-
Rose-John, S.1
Heinrich, P.C.2
-
75
-
-
0025303609
-
Studies on the structure and regulation of the human hepatic interleukin-6 receptor
-
Rose-John, S., Schooltink, H., Lenz, D., Hipp, E., Dufhues, G., Schmitz, H., Schiel, X., Hirano, T., Kishimoto, T. & Heinrich, P.C. (1990). Studies on the structure and regulation of the human hepatic interleukin-6 receptor. Eur. J. Biochem., 190, 79-83.
-
(1990)
Eur. J. Biochem.
, vol.190
, pp. 79-83
-
-
Rose-John, S.1
Schooltink, H.2
Lenz, D.3
Hipp, E.4
Dufhues, G.5
Schmitz, H.6
Schiel, X.7
Hirano, T.8
Kishimoto, T.9
Heinrich, P.C.10
-
76
-
-
0028869476
-
Cytokines and the nervous system II: Actions and mechansims of action
-
Rothwell, N.J. & Hopkins, S.J. (1995). Cytokines and the nervous system II: actions and mechansims of action. Trends Neurosci., 18, 130-136.
-
(1995)
Trends Neurosci.
, vol.18
, pp. 130-136
-
-
Rothwell, N.J.1
Hopkins, S.J.2
-
77
-
-
0023691651
-
Induction of neuronal differentiation in PCo12: Cells by B-cell stimulatory factor 2/interleukin 6
-
Satoh, T., Nakamura, S., Taga, T., Matsuda, T., Hirano, T., Kishimoto, T. & Kaziro, Y. (1988). Induction of neuronal differentiation in PCo12: cells by B-cell stimulatory factor 2/interleukin 6. Mol. Cell Biol., 8, 3546-3549.
-
(1988)
Mol. Cell Biol.
, vol.8
, pp. 3546-3549
-
-
Satoh, T.1
Nakamura, S.2
Taga, T.3
Matsuda, T.4
Hirano, T.5
Kishimoto, T.6
Kaziro, Y.7
-
78
-
-
0027367308
-
Expression of cytokine receptors in cultured neuronal and glial cells
-
Sawada, M., Itoh, Y., Suzumura, A. & Marunouchi, T. (1993). Expression of cytokine receptors in cultured neuronal and glial cells. Neurosci. Lett., 160, 131-134.
-
(1993)
Neurosci. Lett.
, vol.160
, pp. 131-134
-
-
Sawada, M.1
Itoh, Y.2
Suzumura, A.3
Marunouchi, T.4
-
79
-
-
2442754920
-
The IL-6/sIL-6R fusion protein promotes neurite outgrowth and neuronal survival in cultured enteric neurons
-
Schäfer, K.H., Mestres, P., März, P. & Rose-John, S. (1999). The IL-6/sIL-6R fusion protein promotes neurite outgrowth and neuronal survival in cultured enteric neurons. J. Interferon Cytokine Res., 19, 527-532.
-
(1999)
J. Interferon Cytokine Res.
, vol.19
, pp. 527-532
-
-
Schäfer, K.H.1
Mestres, P.2
März, P.3
Rose-John, S.4
-
80
-
-
0026996678
-
Peripheral and central regulation of IL-6 gene expression in endotoxin-treated rats
-
Schobitz, B., Holsboer, F., Kikkert, R., Sutanto, W. & De Kloet, E.R. (1992). Peripheral and central regulation of IL-6 gene expression in endotoxin-treated rats. Endocr. Regul., 26, 103-109.
-
(1992)
Endocr. Regul.
, vol.26
, pp. 103-109
-
-
Schobitz, B.1
Holsboer, F.2
Kikkert, R.3
Sutanto, W.4
De Kloet, E.R.5
-
81
-
-
0028072563
-
Ciliary neurotrophic factor
-
Sendtner, M., Carroll, P., Holtmann, B., Hughes, R.A. & Thoenen, H. (1994a). Ciliary neurotrophic factor. J. Neurobiol., 25, 1436-1453.
-
(1994)
J. Neurobiol.
, vol.25
, pp. 1436-1453
-
-
Sendtner, M.1
Carroll, P.2
Holtmann, B.3
Hughes, R.A.4
Thoenen, H.5
-
82
-
-
0027989754
-
Actions of CNTF and neurotrophins on degenerating motoneurons: Preclinical studies and clinical implications
-
Sendtner, M., Dittrich, F., Hughes, R.A. & Thoenen, H. (1994b). Actions of CNTF and neurotrophins on degenerating motoneurons: preclinical studies and clinical implications. J. Neurol. Sci., 124 (Suppl.), 77-83.
-
(1994)
J. Neurol. Sci.
, vol.124
, Issue.SUPPL.
, pp. 77-83
-
-
Sendtner, M.1
Dittrich, F.2
Hughes, R.A.3
Thoenen, H.4
-
83
-
-
0030156037
-
Cryptic physiological trophic support of motoneurons by LIF revealed by double gene targeting of CNTF and LIF
-
Sendtner, M., Gotz, R., Holtmann, B., Escary, J.L., Masu, Y., Carroll, P., Wolf, E., Brem, G., Brulet, P. & Thoenen, H. (1996). Cryptic physiological trophic support of motoneurons by LIF revealed by double gene targeting of CNTF and LIF. Curr. Biol., 6, 686-694.
-
(1996)
Curr. Biol.
, vol.6
, pp. 686-694
-
-
Sendtner, M.1
Gotz, R.2
Holtmann, B.3
Escary, J.L.4
Masu, Y.5
Carroll, P.6
Wolf, E.7
Brem, G.8
Brulet, P.9
Thoenen, H.10
-
84
-
-
0030758501
-
Endogenous ciliary neurotrophic factor is a lesion factor for axotomized motoneurons in adult mice
-
Sendtner, M., Götz, R., Holtmann, B. & Thoenen, H. (1997). Endogenous ciliary neurotrophic factor is a lesion factor for axotomized motoneurons in adult mice. J. Neurosci., 17, 6999-7006.
-
(1997)
J. Neurosci.
, vol.17
, pp. 6999-7006
-
-
Sendtner, M.1
Götz, R.2
Holtmann, B.3
Thoenen, H.4
-
85
-
-
0026694239
-
Synthesis and localization of ciliary neurotrophic factor in the sciatic nerve of the adult rat after lesion and during regeneration
-
Sendtner, M., Stöckli, K.A. & Thoenen, H. (1992). Synthesis and localization of ciliary neurotrophic factor in the sciatic nerve of the adult rat after lesion and during regeneration. J. Cell Biol., 118, 139-148.
-
(1992)
J. Cell Biol.
, vol.118
, pp. 139-148
-
-
Sendtner, M.1
Stöckli, K.A.2
Thoenen, H.3
-
86
-
-
0027145507
-
Cytokine structural taxonomy and mechanism of receptor engagement
-
Sprang, S.R. & Bazan, J.F. (1993). Cytokine structural taxonomy and mechanism of receptor engagement. Curr. Opin. Struct. Biol., 3, 815-827.
-
(1993)
Curr. Opin. Struct. Biol.
, vol.3
, pp. 815-827
-
-
Sprang, S.R.1
Bazan, J.F.2
-
87
-
-
0027181529
-
Recombinant soluble human interleukin-6 receptor. Expression in Escherichia coli, renaturation and purification
-
Stoyan, T., Michaelis, U., Schooltink, H., Van Dam, M., Rudolph, R., Heinrich, P.C. & Rose-John, S. (1993). Recombinant soluble human interleukin-6 receptor. Expression in Escherichia coli, renaturation and purification. Eur. J. Biochem., 216, 239-245.
-
(1993)
Eur. J. Biochem.
, vol.216
, pp. 239-245
-
-
Stoyan, T.1
Michaelis, U.2
Schooltink, H.3
Van Dam, M.4
Rudolph, R.5
Heinrich, P.C.6
Rose-John, S.7
-
88
-
-
0028930202
-
gp130 and c-Kit signalings synergize for ex vivo expansion of human primitive hemopoietic progenitor cells
-
Sui, X., Tsuji, K., Tanaka, R., Tajima, S., Muraoka, K., Ebihara, Y., Ikebuchi, K., Yasukawa, K., Taga, T., Kishimoto, T. & Nakahata, T. (1995). gp130 and c-Kit signalings synergize for ex vivo expansion of human primitive hemopoietic progenitor cells. Proc. Natl Acad. Sci. USA, 92, 2859-2863.
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 2859-2863
-
-
Sui, X.1
Tsuji, K.2
Tanaka, R.3
Tajima, S.4
Muraoka, K.5
Ebihara, Y.6
Ikebuchi, K.7
Yasukawa, K.8
Taga, T.9
Kishimoto, T.10
Nakahata, T.11
-
89
-
-
0024393839
-
Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130
-
Taga, T., Hibi, M., Hirata, Y., Yamasaki, K., Yasukawa, K., Matsuda, T., Hirano, T. & Kishimoto, T. (1989). Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130. Cell, 58, 573-581.
-
(1989)
Cell
, vol.58
, pp. 573-581
-
-
Taga, T.1
Hibi, M.2
Hirata, Y.3
Yamasaki, K.4
Yasukawa, K.5
Matsuda, T.6
Hirano, T.7
Kishimoto, T.8
-
90
-
-
0030890718
-
gp130 and the interleukin-6 family of cytokines
-
Taga, T. & Kishimoto, T. (1997). gp130 and the interleukin-6 family of cytokines. Annu. Rev. Immunol., 15, 797-819.
-
(1997)
Annu. Rev. Immunol.
, vol.15
, pp. 797-819
-
-
Taga, T.1
Kishimoto, T.2
-
91
-
-
0033593617
-
Trophic effects of cardiotrophin-1 and interleukin-11 on rat dorsal root ganglion neurons in vitro
-
Thier, M., Hall, M., Heath, J.K., Pennica, D. & Weis, J. (1999a). Trophic effects of cardiotrophin-1 and interleukin-11 on rat dorsal root ganglion neurons in vitro. Brain Res. Mol Brain Res., 64, 80-84.
-
(1999)
Brain Res. Mol Brain Res.
, vol.64
, pp. 80-84
-
-
Thier, M.1
Hall, M.2
Heath, J.K.3
Pennica, D.4
Weis, J.5
-
92
-
-
0345004849
-
Interleukin-6 (IL-6) supports survival of sensory neurons: Autocrine trophic effects of IL-6 and soluble IL-6 receptor and enhanced activity of an IL-6 designer cytokine
-
Thier, M., März, P., Otten, U., Weis, J. & Rose-John, S. (1999b). Interleukin-6 (IL-6) supports survival of sensory neurons: autocrine trophic effects of IL-6 and soluble IL-6 receptor and enhanced activity of an IL-6 designer cytokine. J. Neurosci. Res., 55, 411-422.
-
(1999)
J. Neurosci. Res.
, vol.55
, pp. 411-422
-
-
Thier, M.1
März, P.2
Otten, U.3
Weis, J.4
Rose-John, S.5
-
93
-
-
0029931316
-
Engineering human interleukin-6 to obtain variants with strongly enhanced bioactivity
-
Toniatti, C., Cabibbo, A., Sporena, E., Salvati, A.L., Cerretani, M., Serafini, S., Lahm, A., Cortese, R. & Ciliberto, G. (1996). Engineering human interleukin-6 to obtain variants with strongly enhanced bioactivity. EMBO J., 15, 2726-2737.
-
(1996)
EMBO J.
, vol.15
, pp. 2726-2737
-
-
Toniatti, C.1
Cabibbo, A.2
Sporena, E.3
Salvati, A.L.4
Cerretani, M.5
Serafini, S.6
Lahm, A.7
Cortese, R.8
Ciliberto, G.9
-
94
-
-
1842290972
-
Regulation of the genes encoding Interleukin-6, its receptor, and gp130 in the rat brain in response to the immune activator lipopolysaccharide and the proinflammatory cytokine interleukin-1beta
-
Vallieres, L. & Rivest, S. (1997). Regulation of the genes encoding Interleukin-6, its receptor, and gp130 in the rat brain in response to the immune activator lipopolysaccharide and the proinflammatory cytokine interleukin-1beta. J. Neurochem., 69, 1668-1683.
-
(1997)
J. Neurochem.
, vol.69
, pp. 1668-1683
-
-
Vallieres, L.1
Rivest, S.2
-
95
-
-
0029061551
-
Targeted disruption of the low-affinity leukemia inhibitory factor receptor gene causes placental, skeletal, neural and metabolic defects and results in perinatal death
-
Ware, C.B., Horowitz, M.C., Renshaw, B.R., Hunt, J.S., Liggitt, D., Koblar, S.A., Gliniak, B.C., McKenna, H.J., Papayannopoulou, T., Thoma, B., Cheng, L., Donovan, P.J., Peschon, J.J., Bartlett, P.F., Willis, C.R., Wright, B.D., Carpenter, M.K., Davison, B.L. & Gearing, D.P. (1995). Targeted disruption of the low-affinity leukemia inhibitory factor receptor gene causes placental, skeletal, neural and metabolic defects and results in perinatal death. Development, 121, 1283-1299.
-
(1995)
Development
, vol.121
, pp. 1283-1299
-
-
Ware, C.B.1
Horowitz, M.C.2
Renshaw, B.R.3
Hunt, J.S.4
Liggitt, D.5
Koblar, S.A.6
Gliniak, B.C.7
McKenna, H.J.8
Papayannopoulou, T.9
Thoma, B.10
Cheng, L.11
Donovan, P.J.12
Peschon, J.J.13
Bartlett, P.F.14
Willis, C.R.15
Wright, B.D.16
Carpenter, M.K.17
Davison, B.L.18
Gearing, D.P.19
-
96
-
-
0031682226
-
Increased expression of CNTF receptor alpha in denervated human skeletal muscle
-
Weis, J., Lie, D.C., Ragoss, U., Zuchner, S.L., Schroder, J.M., Karpati, G., Farruggella, T., Stahl, N., Yancopoulos, G.D. & DiStefano, P.S. (1998). Increased expression of CNTF receptor alpha in denervated human skeletal muscle. J. Neuropathol. Exp. Neurol., 57, 850-857.
-
(1998)
J. Neuropathol. Exp. Neurol.
, vol.57
, pp. 850-857
-
-
Weis, J.1
Lie, D.C.2
Ragoss, U.3
Zuchner, S.L.4
Schroder, J.M.5
Karpati, G.6
Farruggella, T.7
Stahl, N.8
Yancopoulos, G.D.9
DiStefano, P.S.10
-
97
-
-
0030050701
-
Binding in the growth hormone receptor complex
-
Wells, J.A. (1996). Binding in the growth hormone receptor complex. Proc. Natl Acad. Sci. USA, 93, 1-6.
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 1-6
-
-
Wells, J.A.1
-
98
-
-
0027453380
-
Cytokine indices in Alzheimer's temporal cortex: No changes in mature IL-1 beta or IL-1RA but increases in the associated acute phase proteins IL-6, alpha 2-macroglobulin and C-reactive protein
-
Wood, J.A., Wood, P.L., Ryan, R., Graff Radford, N.R., Pilapil, C., Robitaille, Y. & Quirion, R. (1993). Cytokine indices in Alzheimer's temporal cortex: no changes in mature IL-1 beta or IL-1RA but increases in the associated acute phase proteins IL-6, alpha 2-macroglobulin and C-reactive protein. Brain Res., 629, 245-252.
-
(1993)
Brain Res.
, vol.629
, pp. 245-252
-
-
Wood, J.A.1
Wood, P.L.2
Ryan, R.3
Graff Radford, N.R.4
Pilapil, C.5
Robitaille, Y.6
Quirion, R.7
-
99
-
-
15844406056
-
Induction of neurite outgrowth by interleukin-6 is accompanied by activation of Stat3 signaling pathway in a variant PC12 cell (E2) line
-
Wu, Y.Y. & Bradshaw, R.A. (1996). Induction of neurite outgrowth by interleukin-6 is accompanied by activation of Stat3 signaling pathway in a variant PC12 cell (E2) line. J. Biol. Chem., 271, 13023-13032.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 13023-13032
-
-
Wu, Y.Y.1
Bradshaw, R.A.2
-
100
-
-
0024790913
-
The cholinergic neuronal differentiation factor from heart cells is identical to leukemia inhibitory factor [published erratum appears in Science 1990 Jan 19; 247 (4940), 271]
-
Yamamori, T., Fukada, K., Aebersold, R., Korsching, S., Fann, M.J. & Patterson, P.H. (1989). The cholinergic neuronal differentiation factor from heart cells is identical to leukemia inhibitory factor [published erratum appears in Science 1990 Jan 19; 247 (4940), 271]. Science, 246, 1412-1416.
-
(1989)
Science
, vol.246
, pp. 1412-1416
-
-
Yamamori, T.1
Fukada, K.2
Aebersold, R.3
Korsching, S.4
Fann, M.J.5
Patterson, P.H.6
-
101
-
-
0023685762
-
Cloning and expression of the human interleukin-6 (BSF-2/IFN beta 2) receptor
-
Yamasaki, K., Taga, T., Hirata, Y., Yawata, H., Kawanishi, Y., Seed, B., Taniguchi, T., Hirano, T. & Kishimoto, T. (1988). Cloning and expression of the human interleukin-6 (BSF-2/IFN beta 2) receptor. Science, 241, 825-828.
-
(1988)
Science
, vol.241
, pp. 825-828
-
-
Yamasaki, K.1
Taga, T.2
Hirata, Y.3
Yawata, H.4
Kawanishi, Y.5
Seed, B.6
Taniguchi, T.7
Hirano, T.8
Kishimoto, T.9
-
102
-
-
0026474397
-
Expression of interleukin (IL) -1 beta, IL-6 and their respective receptors in the normal rat brain and after injury
-
Yan, H.Q., Banos, M.A., Herregodts, P., Hooghe, R. & Hooghe Peters, E.L. (1992). Expression of interleukin (IL) -1 beta, IL-6 and their respective receptors in the normal rat brain and after injury. Eur J. Immunol., 22, 2963-2971.
-
(1992)
Eur J. Immunol.
, vol.22
, pp. 2963-2971
-
-
Yan, H.Q.1
Banos, M.A.2
Herregodts, P.3
Hooghe, R.4
Hooghe Peters, E.L.5
-
103
-
-
0030913044
-
Selective upregulation of cytokine receptor subchain and their intracellular signalling molecules after peripheral nerve injury
-
Yao, G.L., Kato, H., Khalil, M., Kiryu, S. & Kiyama, H. (1997). Selective upregulation of cytokine receptor subchain and their intracellular signalling molecules after peripheral nerve injury. Eur J. Neurosci, 9, 1047-1054.
-
(1997)
Eur J. Neurosci
, vol.9
, pp. 1047-1054
-
-
Yao, G.L.1
Kato, H.2
Khalil, M.3
Kiryu, S.4
Kiyama, H.5
-
104
-
-
9044222888
-
Targeted disruption of gp130, a common signal transducer for the interleukin 6 family of cytokines, leads to myocardial and hematological disorders
-
Yoshida, K., Taga, T., Saito, M., Suematsu, S., Kumanogoh, A., Tanaka, T., Fujiwara, H., Hirata, M., Yamagami, T., Nakahata, T., Hirabayashi, T., Yoneda, Y., Tanaka, K., Wang, W.Z., Mori, C., Shiota, K., Yoshida, N. & Kishimoto, T. (1996). Targeted disruption of gp130, a common signal transducer for the interleukin 6 family of cytokines, leads to myocardial and hematological disorders. Proc. Natl Acad. Sci. USA, 93, 407-411.
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 407-411
-
-
Yoshida, K.1
Taga, T.2
Saito, M.3
Suematsu, S.4
Kumanogoh, A.5
Tanaka, T.6
Fujiwara, H.7
Hirata, M.8
Yamagami, T.9
Nakahata, T.10
Hirabayashi, T.11
Yoneda, Y.12
Tanaka, K.13
Wang, W.Z.14
Mori, C.15
Shiota, K.16
Yoshida, N.17
Kishimoto, T.18
-
105
-
-
0032562601
-
Identification and characterization of two distinct truncated forms of gp130 and a soluble form of leukemia inhibitory factor receptor alpha-chain in normal human urine and plasma
-
Zhang, J.G., Zhang, Y., Owczarek, C.M., Ward, L.D., Moritz, R.L., Simpson, R.J., Yasukawa, K. & Nicola, N.A. (1998). Identification and characterization of two distinct truncated forms of gp130 and a soluble form of leukemia inhibitory factor receptor alpha-chain in normal human urine and plasma. J. Biol. Chem., 273, 10798-10805.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 10798-10805
-
-
Zhang, J.G.1
Zhang, Y.2
Owczarek, C.M.3
Ward, L.D.4
Moritz, R.L.5
Simpson, R.J.6
Yasukawa, K.7
Nicola, N.A.8
-
106
-
-
0026721190
-
The hepatic interleukin-6 receptor. Down-regulation of the interleukin-6 binding subunit (gp80) by its ligand
-
Zohlnhöfer, D., Graeve, L., Rose-John, S., Schooltink, H., Dittrich, E. & Heinrich, P.C. (1992). The hepatic interleukin-6 receptor. Down-regulation of the interleukin-6 binding subunit (gp80) by its ligand. FEBS Lett., 306, 219-222.
-
(1992)
FEBS Lett.
, vol.306
, pp. 219-222
-
-
Zohlnhöfer, D.1
Graeve, L.2
Rose-John, S.3
Schooltink, H.4
Dittrich, E.5
Heinrich, P.C.6
|