Interleukin-6/soluble interleukin-6 receptor complex reduces infarct size via inhibiting myocardial apoptosis

Laboratory Investigation

Volumn 85, Issue 10, 2005, Pages 1210-1223

  Matsushita, Kenichi ^a   Iwanaga, Shiro ^a   Oda, Takahiro ^a   Kimura, Kensuke ^a   Shimada, Megumi ^a   Sano, Makoto ^b   Umezawa, Akihiro ^b,c   Hata, Jun Ichi ^b,d   Ogawa, Satoshi ^a  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KEIO UNIVERSITY   (Japan)

^c NATIONAL RESEARCH INSTITUTE FOR CHILD HEALTH AND DEVELOPMENT   (Japan)

^d NATIONAL CENTER FOR CHILD HEALTH AND DEVELOPMENT   (Japan)

Author keywords

Apoptosis; gp130; Interleukin 6; Myocardial infarction; Reperfusion

Indexed keywords

GENOMIC DNA; GLYCOPROTEIN; GLYCOPROTEIN 130; INTERLEUKIN 6 RECEPTOR; RECOMBINANT INTERLEUKIN 6; SOLUBLE INTERLEUKIN 6 RECEPTOR; TETRAZOLIUM; UNCLASSIFIED DRUG;

ACUTE HEART INFARCTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; GEL ELECTROPHORESIS; HEART INFARCTION SIZE; HEART MUSCLE CELL; LEFT CORONARY ARTERY; MALE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; REACTION TIME; REPERFUSION INJURY; RISK ASSESSMENT; STATISTICAL SIGNIFICANCE; TISSUE SECTION;

ANIMALS; APOPTOSIS; ELECTROPHORESIS, AGAR GEL; HEART RATE; HUMANS; IN SITU NICK-END LABELING; INTERLEUKIN-6; MALE; MICROSCOPY, ELECTRON, TRANSMISSION; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION; MYOCARDIUM; MYOCYTES, CARDIAC; RATS; RATS, WISTAR; RECEPTORS, INTERLEUKIN-6; SOLUBILITY; VENTRICULAR FUNCTION, LEFT;

EID: 25144477563     PISSN: 00236837     EISSN: None     Source Type: Journal    
DOI: 10.1038/labinvest.3700322     Document Type: Article

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