The function of the soluble interleukin 6 (IL-6) receptor in vivo: Sensitization of human soluble IL-6 receptor transgenic mice towards IL-6 and prolongation of the plasma half-life of IL-6

Journal of Experimental Medicine

Volumn 183, Issue 4, 1996, Pages 1399-1406

  Peters, Malte ^a   Jacobs, Stephan ^a   Ehlers, Marc ^a   Vollmer, Petra ^a   Müllberg, Jürgen ^b   Wolf, Eckhard ^c   Brem, Gottfried ^d   Meyer Zum Büschenfelde, Karl Herman ^a   Rose John, Stefan ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b AMGEN INC   (United States)

^c UNIVERSITY OF MUNICH   (Germany)

^d UNIVERSITY OF VETERINARY MEDICINE   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR;

ACUTE PHASE RESPONSE; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; HUMAN; MOUSE; NONHUMAN; PLASMA HALF LIFE; PRIORITY JOURNAL; PROTEIN INDUCTION; RECEPTOR AFFINITY; RECEPTOR SOLUBILIZATION; TRANSGENIC MOUSE;

ACUTE-PHASE REACTION; ANIMALS; ANTIGENS, CD; CARRIER PROTEINS; HALF-LIFE; HAPTOGLOBINS; HUMANS; INTERLEUKIN-6; LIVER; MICE; MICE, TRANSGENIC; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); RECEPTORS, INTERLEUKIN; RECEPTORS, INTERLEUKIN-6; SOLUBILITY; SPECIES SPECIFICITY;

EID: 0029863504     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.183.4.1399     Document Type: Article

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