-
1
-
-
80053087484
-
Inflammasome is a central player in the induction of obesity and insulin resistance
-
2-s2.0-80053087484 10.1073/pnas.1100255108
-
Stienstra R., van Diepen J. A., Tack C. J., Zaki M. H., Van De Veerdonk F. L., Perera D., Neale G. A., Hooiveld G. J., Hijmans A., Vroegrijk I., Van Den Berg S., Romijn J., Rensen P. C. N., Joosten L. A. B., Netea M. G., Kanneganti T.-D., Inflammasome is a central player in the induction of obesity and insulin resistance. Proceedings of the National Academy of Sciences of the United States of America 2011 108 37 15324 15329 2-s2.0-80053087484 10.1073/pnas.1100255108
-
(2011)
Proceedings of the National Academy of Sciences of the United States of America
, vol.108
, Issue.37
, pp. 15324-15329
-
-
Stienstra, R.1
Van Diepen, J.A.2
Tack, C.J.3
Zaki, M.H.4
Van De Veerdonk, F.L.5
Perera, D.6
Neale, G.A.7
Hooiveld, G.J.8
Hijmans, A.9
Vroegrijk, I.10
Van Den Berg, S.11
Romijn, J.12
Rensen, P.C.N.13
Joosten, L.A.B.14
Netea, M.G.15
Kanneganti, T.-D.16
-
2
-
-
42649101995
-
NLRs at the intersection of cell death and immunity
-
DOI 10.1038/nri2296, PII NRI2296
-
Ting J. P.-Y., Willingham S. B., Bergstralh D. T., NLRs at the intersection of cell death and immunity. Nature Reviews Immunology 2008 8 5 372 379 2-s2.0-42649101995 10.1038/nri2296 (Pubitemid 351596409)
-
(2008)
Nature Reviews Immunology
, vol.8
, Issue.5
, pp. 372-379
-
-
Ting, J.P.-Y.1
Willingham, S.B.2
Bergstralh, D.T.3
-
3
-
-
51349096358
-
Molecular regulation of inflammation and cell death
-
2-s2.0-51349096358 10.1016/j.cyto.2008.07.015
-
Yeretssian G., Labbé K., Saleh M., Molecular regulation of inflammation and cell death. Cytokine 2008 43 3 380 390 2-s2.0-51349096358 10.1016/j.cyto.2008.07.015
-
(2008)
Cytokine
, vol.43
, Issue.3
, pp. 380-390
-
-
Yeretssian, G.1
Labbé, K.2
Saleh, M.3
-
5
-
-
77749245836
-
Inflammasomes as microbial sensors
-
2-s2.0-77749245836 10.1002/eji.200940180
-
Franchi L., Muñoz-Planillo R., Reimer T., Eigenbrod T., Núñez G., Inflammasomes as microbial sensors. European Journal of Immunology 2010 40 3 611 615 2-s2.0-77749245836 10.1002/eji.200940180
-
(2010)
European Journal of Immunology
, vol.40
, Issue.3
, pp. 611-615
-
-
Franchi, L.1
Muñoz-Planillo, R.2
Reimer, T.3
Eigenbrod, T.4
Núñez, G.5
-
6
-
-
77957228318
-
Central roles of NLRs and inflammasomes in viral infection
-
2-s2.0-77957228318 10.1038/nri2851
-
Kanneganti T.-D., Central roles of NLRs and inflammasomes in viral infection. Nature Reviews Immunology 2010 10 10 688 698 2-s2.0-77957228318 10.1038/nri2851
-
(2010)
Nature Reviews Immunology
, vol.10
, Issue.10
, pp. 688-698
-
-
Kanneganti, T.-D.1
-
7
-
-
78649526394
-
Sterile inflammation: Sensing and reacting to damage
-
2-s2.0-78649526394 10.1038/nri2873
-
Chen G. Y., Nuñez G., Sterile inflammation: sensing and reacting to damage. Nature Reviews Immunology 2010 10 12 826 837 2-s2.0-78649526394 10.1038/nri2873
-
(2010)
Nature Reviews Immunology
, vol.10
, Issue.12
, pp. 826-837
-
-
Chen, G.Y.1
Nuñez, G.2
-
8
-
-
79951642032
-
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
-
2-s2.0-79951642032 10.1038/ni.1980
-
Nakahira K., Haspel J. A., Rathinam V. A. K., Lee S.-J., Dolinay T., Lam H. C., Englert J. A., Rabinovitch M., Cernadas M., Kim H. P., Fitzgerald K. A., Ryter S. W., Choi A. M. K., Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome. Nature Immunology 2011 12 3 222 230 2-s2.0-79951642032 10.1038/ni.1980
-
(2011)
Nature Immunology
, vol.12
, Issue.3
, pp. 222-230
-
-
Nakahira, K.1
Haspel, J.A.2
Rathinam, V.A.K.3
Lee, S.-J.4
Dolinay, T.5
Lam, H.C.6
Englert, J.A.7
Rabinovitch, M.8
Cernadas, M.9
Kim, H.P.10
Fitzgerald, K.A.11
Ryter, S.W.12
Choi, A.M.K.13
-
9
-
-
78651393239
-
A role for mitochondria in NLRP3 inflammasome activation
-
Zhou R., Yazdi A. S., Menu P., Tschopp J., A role for mitochondria in NLRP3 inflammasome activation. Nature 2011 469 221 225
-
(2011)
Nature
, vol.469
, pp. 221-225
-
-
Zhou, R.1
Yazdi, A.S.2
Menu, P.3
Tschopp, J.4
-
10
-
-
47849085872
-
The NALP3 inflammasome is involved in the innate immune response to amyloid- β
-
2-s2.0-47849085872 10.1038/ni.1636
-
Halle A., Hornung V., Petzold G. C., Stewart C. R., Monks B. G., Reinheckel T., Fitzgerald K. A., Latz E., Moore K. J., Golenbock D. T., The NALP3 inflammasome is involved in the innate immune response to amyloid- β Nature Immunology 2008 9 8 857 865 2-s2.0-47849085872 10.1038/ni.1636
-
(2008)
Nature Immunology
, vol.9
, Issue.8
, pp. 857-865
-
-
Halle, A.1
Hornung, V.2
Petzold, G.C.3
Stewart, C.R.4
Monks, B.G.5
Reinheckel, T.6
Fitzgerald, K.A.7
Latz, E.8
Moore, K.J.9
Golenbock, D.T.10
-
11
-
-
47849097202
-
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
-
2-s2.0-47849097202 10.1038/ni.1631
-
Hornung V., Bauernfeind F., Halle A., Samstad E. O., Kono H., Rock K. L., Fitzgerald K. A., Latz E., Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nature Immunology 2008 9 8 847 856 2-s2.0-47849097202 10.1038/ni.1631
-
(2008)
Nature Immunology
, vol.9
, Issue.8
, pp. 847-856
-
-
Hornung, V.1
Bauernfeind, F.2
Halle, A.3
Samstad, E.O.4
Kono, H.5
Rock, K.L.6
Fitzgerald, K.A.7
Latz, E.8
-
12
-
-
79751512463
-
The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance
-
2-s2.0-79751512463 10.1038/nm.2279
-
Vandanmagsar B., Youm Y.-H., Ravussin A., Galgani J. E., Stadler K., Mynatt R. L., Ravussin E., Stephens J. M., Dixit V. D., The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance. Nature Medicine 2011 17 2 179 188 2-s2.0-79751512463 10.1038/nm.2279
-
(2011)
Nature Medicine
, vol.17
, Issue.2
, pp. 179-188
-
-
Vandanmagsar, B.1
Youm, Y.-H.2
Ravussin, A.3
Galgani, J.E.4
Stadler, K.5
Mynatt, R.L.6
Ravussin, E.7
Stephens, J.M.8
Dixit, V.D.9
-
13
-
-
79955038882
-
Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling
-
2-s2.0-79955038882 10.1038/ni.2022
-
Wen H., Gris D., Lei Y., Jha S., Zhang L., Huang M. T.-H., Brickey W. J., Ting J. P.-Y., Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling. Nature Immunology 2011 12 5 408 415 2-s2.0-79955038882 10.1038/ni.2022
-
(2011)
Nature Immunology
, vol.12
, Issue.5
, pp. 408-415
-
-
Wen, H.1
Gris, D.2
Lei, Y.3
Jha, S.4
Zhang, L.5
Huang, M.T.-H.6
Brickey, W.J.7
Ting, J.P.-Y.8
-
14
-
-
84871314266
-
Multiple binding sites on the pyrin domain of ASC protein allow self-association and interaction with NLRP3 protein
-
Vajjhala P. R., Mirams R. E., Hill J. M., Multiple binding sites on the pyrin domain of ASC protein allow self-association and interaction with NLRP3 protein. The Journal of Biological Chemistry 2012 287 41732 41743
-
(2012)
The Journal of Biological Chemistry
, vol.287
, pp. 41732-41743
-
-
Vajjhala, P.R.1
Mirams, R.E.2
Hill, J.M.3
-
15
-
-
77955770771
-
Role of IL-1 β in type 2 diabetes
-
2-s2.0-77955770771 10.1097/MED.0b013e32833bf6dc
-
Dinarello C. A., Donath M. Y., Mandrup-Poulsen T., Role of IL-1 β in type 2 diabetes. Current Opinion in Endocrinology, Diabetes and Obesity 2010 17 4 314 321 2-s2.0-77955770771 10.1097/MED.0b013e32833bf6dc
-
(2010)
Current Opinion in Endocrinology, Diabetes and Obesity
, vol.17
, Issue.4
, pp. 314-321
-
-
Dinarello, C.A.1
Donath, M.Y.2
Mandrup-Poulsen, T.3
-
16
-
-
0345700727
-
Inflammatory cytokines and the risk to develop type 2 diabetes: Results of the prospective population-based European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam study
-
DOI 10.2337/diabetes.52.3.812
-
Spranger J., Kroke A., Möhlig M., Hoffmann K., Bergmann M. M., Ristow M., Boeing H., Pfeiffer A. F. H., Inflammatory cytokines and the risk to develop type 2 diabetes: results of the prospective population-based European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam study. Diabetes 2003 52 3 812 817 2-s2.0-0345700727 10.2337/diabetes.52.3.812 (Pubitemid 36323590)
-
(2003)
Diabetes
, vol.52
, Issue.3
, pp. 812-817
-
-
Spranger, J.1
Kroke, A.2
Mohlig, M.3
Hoffmann, K.4
Bergmann, M.M.5
Ristow, M.6
Boeing, H.7
Pfeiffer, A.F.H.8
-
17
-
-
33845873659
-
Interleukin-1β-induced insulin resistance in adipocytes through down-regulation of insulin receptor substrate-1 expression
-
DOI 10.1210/en.2006-0692
-
Jager J., Grémeaux T., Cormont M., Le Marchand-Brustel Y., Tanti J.-F., Interleukin-1 β -induced insulin resistance in adipocytes through down-regulation of insulin receptor substrate-1 expression. Endocrinology 2007 148 1 241 251 2-s2.0-33845873659 10.1210/en.2006-0692 (Pubitemid 46021456)
-
(2007)
Endocrinology
, vol.148
, Issue.1
, pp. 241-251
-
-
Jager, J.1
Gremeaux, T.2
Cormont, M.3
Le Marchand-Brustel, Y.4
Tanti, J.-F.5
-
18
-
-
0031596597
-
Interleukin 1β and interleukin 6, but not tumor necrosis factor α, inhibit insulin-stimulated glycogen synthesis in rat hepatocytes
-
DOI 10.1002/hep.510270515
-
Kanemaki T., Kitade H., Kaibori M., Sakitani K., Hiramatsu Y., Kamiyama Y., Ito S., Okumura T., Interleukin 1 β and interleukin 6, but not tumor necrosis factor α inhibit insulin-stimulated glycogen synthesis in rat hepatocytes. Hepatology 1998 27 5 1296 1303 2-s2.0-0031596597 10.1002/hep.510270515 (Pubitemid 28227856)
-
(1998)
Hepatology
, vol.27
, Issue.5
, pp. 1296-1303
-
-
Kanemaki, T.1
Kitade, H.2
Kaibori, M.3
Sakitani, K.4
Hiramatsu, Y.5
Kamiyama, Y.6
Ito, S.7
Okumura, T.8
-
19
-
-
33845534203
-
The effect of intensive glycemic treatment on coronary artery calcification in type 1 diabetic participants of the diabetes control and complications trial/epidemiology of diabetes interventions and complications (DCCT/EDIC) study
-
DOI 10.2337/db06-0653
-
Cleary P. A., Orchard T. J., Genuth S., Wong N. D., Detrano R., Backlund J.-Y. C., Zinman B., Jacobson A., Sun W., Lachin J. M., Nathan D. M., The effect of intensive glycemic treatment on coronary artery calcification in type 1 diabetic participants of the diabetes control and complications trial/epidemiology of diabetes interventions and complications (DCCT/EDIC) study. Diabetes 2006 55 12 3556 3565 2-s2.0-33845534203 10.2337/db06-0653 (Pubitemid 44923617)
-
(2006)
Diabetes
, vol.55
, Issue.12
, pp. 3556-3565
-
-
Cleary, P.A.1
Orchard, T.J.2
Genuth, S.3
Wong, N.D.4
Detrano, R.5
Backlund, J.-Y.C.6
Zinman, B.7
Jacobson, A.8
Sun, W.9
Lachin, J.M.10
Nathan, D.M.11
-
20
-
-
34247170807
-
Interleukin-1-receptor antagonist in type 2 diabetes mellitus
-
DOI 10.1056/NEJMoa065213
-
Larsen C. M., Faulenbach M., Vaag A., Vølund A., Ehses J. A., Seifert B., Mandrup-Poulsen T., Donath M. Y., Interleukin-1-receptor antagonist in type 2 diabetes mellitus. The New England Journal of Medicine 2007 356 15 1517 1526 2-s2.0-34247170807 10.1056/NEJMoa065213 (Pubitemid 46588416)
-
(2007)
New England Journal of Medicine
, vol.356
, Issue.15
, pp. 1517-1526
-
-
Larsen, C.M.1
Faulenbach, M.2
Vaag, A.3
Volund, A.4
Ehses, J.A.5
Seifert, B.6
Mandrup-Poulsen, T.7
Donath, M.Y.8
-
21
-
-
78649498271
-
The inflammasome-mediated caspase-1 activation controls adipocyte differentiation and insulin sensitivity
-
2-s2.0-78649498271 10.1016/j.cmet.2010.11.011
-
Stienstra R., Joosten L. A. B., Koenen T., Van Tits B., Van Diepen J. A., Van Den Berg S. A. A., Rensen P. C. N., Voshol P. J., Fantuzzi G., Hijmans A., Kersten S., Müller M., Van Den Berg W. B., Van Rooijen N., Wabitsch M., Kullberg B.-J., Van Der Meer J. W. M., Kanneganti T., Tack C. J., Netea M. G., The inflammasome-mediated caspase-1 activation controls adipocyte differentiation and insulin sensitivity. Cell Metabolism 2010 12 6 593 605 2-s2.0-78649498271 10.1016/j.cmet.2010.11.011
-
(2010)
Cell Metabolism
, vol.12
, Issue.6
, pp. 593-605
-
-
Stienstra, R.1
Joosten, L.A.B.2
Koenen, T.3
Van Tits, B.4
Van Diepen, J.A.5
Van Den Berg, S.A.A.6
Rensen, P.C.N.7
Voshol, P.J.8
Fantuzzi, G.9
Hijmans, A.10
Kersten, S.11
Müller, M.12
Van Den Berg, W.B.13
Van Rooijen, N.14
Wabitsch, M.15
Kullberg, B.-J.16
Van Der Meer, J.W.M.17
Kanneganti, T.18
Tack, C.J.19
Netea, M.G.20
more..
-
22
-
-
84857364150
-
Expression of NLRP3 inflammasome and T cell population markers in adipose tissue are associated with insulin resistance and impaired glucose metabolism in humans
-
2-s2.0-84857364150 10.1016/j.molimm.2012.01.005
-
Goossens G. H., Blaak E. E., Theunissen R., Duijvestijn A. M., Clément K., Tervaert J.-W. C., Thewissen M. M., Expression of NLRP3 inflammasome and T cell population markers in adipose tissue are associated with insulin resistance and impaired glucose metabolism in humans. Molecular Immunology 2012 50 3 142 149 2-s2.0-84857364150 10.1016/j.molimm.2012.01.005
-
(2012)
Molecular Immunology
, vol.50
, Issue.3
, pp. 142-149
-
-
Goossens, G.H.1
Blaak, E.E.2
Theunissen, R.3
Duijvestijn, A.M.4
Clément, K.5
Tervaert, J.-W.C.6
Thewissen, M.M.7
-
23
-
-
84872018875
-
Upregulated NLRP3 inflammasome activation in patients with type 2 diabetes
-
Lee H. M., Kim J. J., Kim H. J., Shong M., Ku B. J., Jo E. K., Upregulated NLRP3 inflammasome activation in patients with type 2 diabetes. Diabetes 2013 62 194 204
-
(2013)
Diabetes
, vol.62
, pp. 194-204
-
-
Lee, H.M.1
Kim, J.J.2
Kim, H.J.3
Shong, M.4
Ku, B.J.5
Jo, E.K.6
-
24
-
-
0036895383
-
Endoplasmic reticulum stress and the development of diabetes: A review
-
Harding H. P., Ron D., Endoplasmic reticulum stress and the development of diabetes: a review. Diabetes 2002 51 supplement 3 S455 S461 2-s2.0-0036895383 (Pubitemid 35403430)
-
(2002)
Diabetes
, vol.51
, Issue.SUPPL. 3
-
-
Harding, H.P.1
Ron, D.2
-
25
-
-
84855605795
-
Endoplasmic reticulum stress, obesity and diabetes
-
2-s2.0-84855605795 10.1016/j.molmed.2011.07.010
-
Cnop M., Foufelle F., Velloso L. A., Endoplasmic reticulum stress, obesity and diabetes. Trends in Molecular Medicine 2012 18 1 59 68 2-s2.0-84855605795 10.1016/j.molmed.2011.07.010
-
(2012)
Trends in Molecular Medicine
, vol.18
, Issue.1
, pp. 59-68
-
-
Cnop, M.1
Foufelle, F.2
Velloso, L.A.3
-
26
-
-
84864320585
-
New insights into ER stress-induced insulin resistance
-
Flamment M., Hajduch E., Ferre P., Foufelle F., New insights into ER stress-induced insulin resistance. Trends in Endocrinology & Metabolism 2012 23 381 390
-
(2012)
Trends in Endocrinology & Metabolism
, vol.23
, pp. 381-390
-
-
Flamment, M.1
Hajduch, E.2
Ferre, P.3
Foufelle, F.4
-
27
-
-
77955024822
-
ER stress in adipocytes inhibits insulin signaling, represses lipolysis, and alters the secretion of adipokines without inhibiting glucose transport
-
2-s2.0-77955024822 10.1055/s-0030-1255034
-
Xu L., Spinas G. A., Niessen M., ER stress in adipocytes inhibits insulin signaling, represses lipolysis, and alters the secretion of adipokines without inhibiting glucose transport. Hormone and Metabolic Research 2010 42 9 643 651 2-s2.0-77955024822 10.1055/s-0030-1255034
-
(2010)
Hormone and Metabolic Research
, vol.42
, Issue.9
, pp. 643-651
-
-
Xu, L.1
Spinas, G.A.2
Niessen, M.3
-
28
-
-
84863163071
-
Lipolysis response to endoplasmic reticulum stress in adipose cells
-
2-s2.0-84857466032 10.1074/jbc.M111.299115
-
Deng J., Liu S., Zou L., Xu C., Geng B., Xu G., Lipolysis response to endoplasmic reticulum stress in adipose cells. The Journal of Biological Chemistry 2012 287 9 6240 6249 2-s2.0-84857466032 10.1074/jbc.M111.299115
-
(2012)
The Journal of Biological Chemistry
, vol.287
, Issue.9
, pp. 6240-6249
-
-
Deng, J.1
Liu, S.2
Zou, L.3
Xu, C.4
Geng, B.5
Xu, G.6
-
29
-
-
77950345571
-
CD14+ monocytes are vulnerable and functionally impaired under endoplasmic reticulum stress in patients with type 2 diabetes
-
2-s2.0-77950345571 10.2337/db09-0659
-
Komura T., Sakai Y., Honda M., Takamura T., Matsushima K., Kaneko S., CD14+ monocytes are vulnerable and functionally impaired under endoplasmic reticulum stress in patients with type 2 diabetes. Diabetes 2010 59 3 634 643 2-s2.0-77950345571 10.2337/db09-0659
-
(2010)
Diabetes
, vol.59
, Issue.3
, pp. 634-643
-
-
Komura, T.1
Sakai, Y.2
Honda, M.3
Takamura, T.4
Matsushima, K.5
Kaneko, S.6
-
30
-
-
84856857478
-
ER stress activates the NLRP3 inflammasome via an UPR-independent pathway
-
2-s2.0-84856857478 10.1038/cddis.2011.132
-
Menu P., Mayor A., Zhou R., Tardivel A., Ichijo H., Mori K., Tschopp J., ER stress activates the NLRP3 inflammasome via an UPR-independent pathway. Cell Death and Disease 2012 3 1, article e261 2-s2.0-84856857478 10.1038/cddis.2011. 132
-
(2012)
Cell Death and Disease
, vol.3
, Issue.1
-
-
Menu, P.1
Mayor, A.2
Zhou, R.3
Tardivel, A.4
Ichijo, H.5
Mori, K.6
Tschopp, J.7
-
31
-
-
84864682160
-
IRE1alpha induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress
-
Lerner A. G., Upton J. P., Praveen P. V., IRE1alpha induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress. Cell Metabolism 2012 16 250 264
-
(2012)
Cell Metabolism
, vol.16
, pp. 250-264
-
-
Lerner, A.G.1
Upton, J.P.2
Praveen, P.V.3
-
32
-
-
34247574122
-
Inflammasome components NALP 1 and 3 show distinct but separate expression profiles in human tissues suggesting a site-specific role in the inflammatory response
-
DOI 10.1369/jhc.6A7101.2006
-
Kummer J. A., Broekhuizen R., Everett H., Agostini L., Kuijk L., Martinon F., Van Bruggen R., Tschopp J., Inflammasome components NALP 1 and 3 show distinct but separate expression profiles in human tissues suggesting a site-specific role in the inflammatory response. Journal of Histochemistry and Cytochemistry 2007 55 5 443 452 2-s2.0-34247574122 10.1369/jhc.6A7101.2006 (Pubitemid 46668626)
-
(2007)
Journal of Histochemistry and Cytochemistry
, vol.55
, Issue.5
, pp. 443-452
-
-
Kummer, J.A.1
Broekhuizen, R.2
Everett, H.3
Agostini, L.4
Kuijk, L.5
Martinon, F.6
Van Bruggen, R.7
Tschopp, J.8
-
33
-
-
84865108051
-
Dietary saturated fatty acids prime the NLRP3 inflammasome via TLR4 in dendritic cells-implications for diet-induced insulin resistance
-
Reynolds C. M., McGillicuddy F. C., Harford K. A., Finucane O. M., Mills K. H., Roche H. M., Dietary saturated fatty acids prime the NLRP3 inflammasome via TLR4 in dendritic cells-implications for diet-induced insulin resistance. Molecular Nutrition & Food Research 2012 56 1212 1222
-
(2012)
Molecular Nutrition & Food Research
, vol.56
, pp. 1212-1222
-
-
Reynolds, C.M.1
McGillicuddy, F.C.2
Harford, K.A.3
Finucane, O.M.4
Mills, K.H.5
Roche, H.M.6
-
34
-
-
0346220288
-
Standard Isolation of Primary Adipose Cells from Mouse Epididymal Fat Pads Induces Inflammatory Mediators and Down-regulates Adipocyte Genes
-
DOI 10.1074/jbc.M305257200
-
Ruan H., Zarnowski M. J., Cushman S. W., Lodish H. F., Standard isolation of primary adipose cells from mouse epididymal fat pads induces inflammatory mediators and down-regulates adipocyte genes. The Journal of Biological Chemistry 2003 278 48 47585 47593 2-s2.0-0346220288 10.1074/jbc.M305257200 (Pubitemid 37523202)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.48
, pp. 47585-47593
-
-
Ruan, H.1
Zarnowski, M.J.2
Cushman, S.W.3
Lodish, H.F.4
-
35
-
-
84872480987
-
Interleukin-1beta regulates fat-liver crosstalk in obesity by auto-paracrine modulation of adipose tissue inflammation and expandability
-
e53626
-
Nov O., Shapiro H., Ovadia H., Interleukin-1beta regulates fat-liver crosstalk in obesity by auto-paracrine modulation of adipose tissue inflammation and expandability. PLoS One 2013 8 e53626
-
(2013)
PLoS One
, vol.8
-
-
Nov, O.1
Shapiro, H.2
Ovadia, H.3
-
36
-
-
77956950157
-
IAPP boosts islet macrophage IL-1 in type 2 diabetes
-
2-s2.0-77956950157 10.1038/ni1010-881
-
Mandrup-Poulsen T., IAPP boosts islet macrophage IL-1 in type 2 diabetes. Nature Immunology 2010 11 10 881 883 2-s2.0-77956950157 10.1038/ni1010-881
-
(2010)
Nature Immunology
, vol.11
, Issue.10
, pp. 881-883
-
-
Mandrup-Poulsen, T.1
-
37
-
-
79960901784
-
Pancreatic β -cell death in response to pro-inflammatory cytokines is distinct from genuine apoptosis
-
2-s2.0-79960901784 10.1371/journal.pone.0022485 e22485
-
Collier J. J., Burke S. J., Eisenhauer M. E., Lu D., Sapp R. C., Frydman C. J., Campagna S. R., Pancreatic β -cell death in response to pro-inflammatory cytokines is distinct from genuine apoptosis. PLoS ONE 2011 6 7 2-s2.0-79960901784 10.1371/journal.pone.0022485 e22485
-
(2011)
PLoS ONE
, vol.6
, Issue.7
-
-
Collier, J.J.1
Burke, S.J.2
Eisenhauer, M.E.3
Lu, D.4
Sapp, R.C.5
Frydman, C.J.6
Campagna, S.R.7
-
38
-
-
79955763329
-
Neutralizing interleukin-1 β (IL-1 β) induces β -cell survival by maintaining PDX1 protein nuclear localization
-
2-s2.0-79955763329 10.1074/jbc.M110.210526
-
Ardestani A., Sauter N. S., Paroni F., Dharmadhikari G., Cho J.-H., Lupi R., Marchetti P., Oberholzer J., Conte J. K., Maedler K., Neutralizing interleukin-1 β (IL-1 β) induces β -cell survival by maintaining PDX1 protein nuclear localization. The Journal of Biological Chemistry 2011 286 19 17144 17155 2-s2.0-79955763329 10.1074/jbc.M110.210526
-
(2011)
The Journal of Biological Chemistry
, vol.286
, Issue.19
, pp. 17144-17155
-
-
Ardestani, A.1
Sauter, N.S.2
Paroni, F.3
Dharmadhikari, G.4
Cho, J.-H.5
Lupi, R.6
Marchetti, P.7
Oberholzer, J.8
Conte, J.K.9
Maedler, K.10
-
39
-
-
75649096002
-
Thioredoxin-interacting protein links oxidative stress to inflammasome activation
-
2-s2.0-75649096002 10.1038/ni.1831
-
Zhou R., Tardivel A., Thorens B., Choi I., Tschopp J., Thioredoxin-interacting protein links oxidative stress to inflammasome activation. Nature Immunology 2010 11 2 136 140 2-s2.0-75649096002 10.1038/ni.1831
-
(2010)
Nature Immunology
, vol.11
, Issue.2
, pp. 136-140
-
-
Zhou, R.1
Tardivel, A.2
Thorens, B.3
Choi, I.4
Tschopp, J.5
-
40
-
-
77956958947
-
Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1 β 2 in type 2 diabetes
-
2-s2.0-77956958947 10.1038/ni.1935
-
Masters S. L., Dunne A., Subramanian S. L., Hull R. L., Tannahill G. M., Sharp F. A., Becker C., Franchi L., Yoshihara E., Chen Z., Mullooly N., Mielke L. A., Harris J., Coll R. C., Mills K. H. G., Mok K. H., Newsholme P., Nuñez G., Yodoi J., Kahn S. E., Lavelle E. C., O'Neill L. A. J., Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1 β 2 in type 2 diabetes. Nature Immunology 2010 11 10 897 904 2-s2.0-77956958947 10.1038/ni.1935
-
(2010)
Nature Immunology
, vol.11
, Issue.10
, pp. 897-904
-
-
Masters, S.L.1
Dunne, A.2
Subramanian, S.L.3
Hull, R.L.4
Tannahill, G.M.5
Sharp, F.A.6
Becker, C.7
Franchi, L.8
Yoshihara, E.9
Chen, Z.10
Mullooly, N.11
Mielke, L.A.12
Harris, J.13
Coll, R.C.14
Mills, K.H.G.15
Mok, K.H.16
Newsholme, P.17
Nuñez, G.18
Yodoi, J.19
Kahn, S.E.20
Lavelle, E.C.21
O'Neill, L.A.J.22
more..
-
41
-
-
80054903245
-
Elimination of the NLRP3-ASC inflammasome protects against chronic obesity-induced pancreatic damage
-
2-s2.0-80054903245 10.1210/en.2011-1326
-
Youm Y.-H., Adijiang A., Vandanmagsar B., Burk D., Ravussin A., Dixit V. D., Elimination of the NLRP3-ASC inflammasome protects against chronic obesity-induced pancreatic damage. Endocrinology 2011 152 11 4039 4045 2-s2.0-80054903245 10.1210/en.2011-1326
-
(2011)
Endocrinology
, vol.152
, Issue.11
, pp. 4039-4045
-
-
Youm, Y.-H.1
Adijiang, A.2
Vandanmagsar, B.3
Burk, D.4
Ravussin, A.5
Dixit, V.D.6
-
42
-
-
82955233684
-
Adipocyte P2X7 receptors expression: A role in modulating inflammatory response in subjects with metabolic syndrome?
-
2-s2.0-82955233684 10.1016/j.atherosclerosis.2011.09.012
-
Madec S., Rossi C., Chiarugi M., Santini E., Salvati A., Ferrannini E., Solini A., Adipocyte P2X7 receptors expression: a role in modulating inflammatory response in subjects with metabolic syndrome? Atherosclerosis 2011 219 2 552 558 2-s2.0-82955233684 10.1016/j.atherosclerosis.2011.09.012
-
(2011)
Atherosclerosis
, vol.219
, Issue.2
, pp. 552-558
-
-
Madec, S.1
Rossi, C.2
Chiarugi, M.3
Santini, E.4
Salvati, A.5
Ferrannini, E.6
Solini, A.7
-
43
-
-
77956029926
-
Interleukin-1 β may mediate insulin resistance in liver-derived cells in response to adipocyte inflammation
-
2-s2.0-77956029926 10.1210/en.2010-0340
-
Nov O., Kohl A., Lewis E. C., Bashan N., Dvir I., Ben-Shlomo S., Fishman S., Wueest S., Konrad D., Rudich A., Interleukin-1 β may mediate insulin resistance in liver-derived cells in response to adipocyte inflammation. Endocrinology 2010 151 9 4247 4256 2-s2.0-77956029926 10.1210/en.2010-0340
-
(2010)
Endocrinology
, vol.151
, Issue.9
, pp. 4247-4256
-
-
Nov, O.1
Kohl, A.2
Lewis, E.C.3
Bashan, N.4
Dvir, I.5
Ben-Shlomo, S.6
Fishman, S.7
Wueest, S.8
Konrad, D.9
Rudich, A.10
-
44
-
-
61749099391
-
Acetaminophen-induced hepatotoxicity in mice is dependent on Tlr9 and the Nalp3 inflammasome
-
2-s2.0-61749099391 10.1172/JCI35958
-
Imaeda A. B., Watanabe A., Sohail M. A., Mahmood S., Mohamadnejad M., Sutterwala F. S., Flavell R. A., Mehal W. Z., Acetaminophen-induced hepatotoxicity in mice is dependent on Tlr9 and the Nalp3 inflammasome. The Journal of Clinical Investigation 2009 119 2 305 314 2-s2.0-61749099391 10.1172/JCI35958
-
(2009)
The Journal of Clinical Investigation
, vol.119
, Issue.2
, pp. 305-314
-
-
Imaeda, A.B.1
Watanabe, A.2
Sohail, M.A.3
Mahmood, S.4
Mohamadnejad, M.5
Sutterwala, F.S.6
Flavell, R.A.7
Mehal, W.Z.8
-
45
-
-
67049108920
-
Inflammasome-mediated regulation of hepatic stellate cells
-
2-s2.0-67049108920 10.1152/ajpgi.90223.2008
-
Watanabe A., Sohail M. A., Gomes D. A., Hashmi A., Nagata J., Sutterwala F. S., Mahmood S., Jhandier M. N., Shi Y., Flavell R. A., Mehal W. Z., Inflammasome-mediated regulation of hepatic stellate cells. American Journal of Physiology 2009 296 6 G1248 G1257 2-s2.0-67049108920 10.1152/ajpgi.90223.2008
-
(2009)
American Journal of Physiology
, vol.296
, Issue.6
-
-
Watanabe, A.1
Sohail, M.A.2
Gomes, D.A.3
Hashmi, A.4
Nagata, J.5
Sutterwala, F.S.6
Mahmood, S.7
Jhandier, M.N.8
Shi, Y.9
Flavell, R.A.10
Mehal, W.Z.11
-
46
-
-
79959573042
-
Fatty acid and endotoxin activate inflammasomes in mouse hepatocytes that release danger signals to stimulate immune cells
-
2-s2.0-79959573042 10.1002/hep.24341
-
Csak T., Ganz M., Pespisa J., Kodys K., Dolganiuc A., Szabo G., Fatty acid and endotoxin activate inflammasomes in mouse hepatocytes that release danger signals to stimulate immune cells. Hepatology 2011 54 1 133 144 2-s2.0-79959573042 10.1002/hep.24341
-
(2011)
Hepatology
, vol.54
, Issue.1
, pp. 133-144
-
-
Csak, T.1
Ganz, M.2
Pespisa, J.3
Kodys, K.4
Dolganiuc, A.5
Szabo, G.6
-
47
-
-
80054737370
-
Lack of interleukin-1 α or interleukin-1 β inhibits transformation of steatosis to steatohepatitis and liver fibrosis in hypercholesterolemic mice
-
2-s2.0-80054737370 10.1016/j.jhep.2011.01.048
-
Kamari Y., Shaish A., Vax E., Shemesh S., Kandel-Kfir M., Arbel Y., Olteanu S., Barshack I., Dotan S., Voronov E., Dinarello C. A., Apte R. N., Harats D., Lack of interleukin-1 α or interleukin-1 β inhibits transformation of steatosis to steatohepatitis and liver fibrosis in hypercholesterolemic mice. Journal of Hepatology 2011 55 5 1086 1094 2-s2.0-80054737370 10.1016/j.jhep.2011.01.048
-
(2011)
Journal of Hepatology
, vol.55
, Issue.5
, pp. 1086-1094
-
-
Kamari, Y.1
Shaish, A.2
Vax, E.3
Shemesh, S.4
Kandel-Kfir, M.5
Arbel, Y.6
Olteanu, S.7
Barshack, I.8
Dotan, S.9
Voronov, E.10
Dinarello, C.A.11
Apte, R.N.12
Harats, D.13
-
48
-
-
84860859210
-
Role of inflammasomes in host defense against Citrobacter rodentium infection
-
Liu Z., Zaki M. H., Vogel P., Gurung P., Finlay B. B., Deng W., Lamkanfi M., Kanneganti T. D., Role of inflammasomes in host defense against Citrobacter rodentium infection. The Journal of Biological Chemistry 2012 287 16955 16964
-
(2012)
The Journal of Biological Chemistry
, vol.287
, pp. 16955-16964
-
-
Liu, Z.1
Zaki, M.H.2
Vogel, P.3
Gurung, P.4
Finlay, B.B.5
Deng, W.6
Lamkanfi, M.7
Kanneganti, T.D.8
-
49
-
-
77952303410
-
The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer
-
2-s2.0-77952303410 10.1084/jem.20100050
-
Allen I. C., Tekippe E. M., Woodford R.-M. T., Uronis J. M., Holl E. K., Rogers A. B., Herfarth H. H., Jobin C., Ting J. P.-Y., The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer. Journal of Experimental Medicine 2010 207 5 1045 1056 2-s2.0-77952303410 10.1084/jem.20100050
-
(2010)
Journal of Experimental Medicine
, vol.207
, Issue.5
, pp. 1045-1056
-
-
Allen, I.C.1
Tekippe, E.M.2
Woodford, R.-M.T.3
Uronis, J.M.4
Holl, E.K.5
Rogers, A.B.6
Herfarth, H.H.7
Jobin, C.8
Ting, J.P.-Y.9
-
50
-
-
77950002937
-
The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis
-
2-s2.0-77950002937 10.1016/j.immuni.2010.03.003
-
Zaki M. H., Boyd K. L., Vogel P., Kastan M. B., Lamkanfi M., Kanneganti T.-D., The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis. Immunity 2010 32 3 379 391 2-s2.0-77950002937 10.1016/j.immuni.2010.03.003
-
(2010)
Immunity
, vol.32
, Issue.3
, pp. 379-391
-
-
Zaki, M.H.1
Boyd, K.L.2
Vogel, P.3
Kastan, M.B.4
Lamkanfi, M.5
Kanneganti, T.-D.6
-
51
-
-
79955846705
-
NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis
-
2-s2.0-79955846705 10.1002/ibd.21478
-
Hirota S. A., Ng J., Lueng A., Khajah M., Parhar K., Li Y., Lam V., Potentier M. S., Ng K., Bawa M., McCafferty D.-M., Rioux K. P., Ghosh S., Xavier R. J., Colgan S. P., Tschopp J., Muruve D., MacDonald J. A., Beck P. L., NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis. Inflammatory Bowel Diseases 2011 17 6 1359 1372 2-s2.0-79955846705 10.1002/ibd.21478
-
(2011)
Inflammatory Bowel Diseases
, vol.17
, Issue.6
, pp. 1359-1372
-
-
Hirota, S.A.1
Ng, J.2
Lueng, A.3
Khajah, M.4
Parhar, K.5
Li, Y.6
Lam, V.7
Potentier, M.S.8
Ng, K.9
Bawa, M.10
McCafferty, D.-M.11
Rioux, K.P.12
Ghosh, S.13
Xavier, R.J.14
Colgan, S.P.15
Tschopp, J.16
Muruve, D.17
Macdonald, J.A.18
Beck, P.L.19
-
52
-
-
34249913692
-
The ICE inhibitor pralnacasan prevents DSS-induced colitis in C57BL/6 mice and suppresses IP-10 mRNA but not TNF-α mRNA expression
-
DOI 10.1007/s10620-007-9802-8
-
Bauer C., Loher F., Dauer M., Mayer C., Lehr H. A., Schönharting M., Hallwachs R., Endres S., Eigler A., The ICE inhibitor pralnacasan prevents DSS-induced colitis in C57BL/6 mice and suppresses IP-10 mRNA but not TNF- α mRNA expression. Digestive Diseases and Sciences 2007 52 7 1642 1652 2-s2.0-34249913692 10.1007/s10620-007-9802-8 (Pubitemid 46870573)
-
(2007)
Digestive Diseases and Sciences
, vol.52
, Issue.7
, pp. 1642-1652
-
-
Bauer, C.1
Loher, F.2
Dauer, M.3
Mayer, C.4
Lehr, H.A.5
Schonharting, M.6
Hallwachs, R.7
Endres, S.8
Eigler, A.9
-
53
-
-
77956128040
-
Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome
-
2-s2.0-77956128040 10.1136/gut.2009.197822
-
Bauer C., Duewell P., Mayer C., Lehr H. A., Fitzgerald K. A., Dauer M., Tschopp J., Endres S., Latz E., Schnurr M., Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome. Gut 2010 59 9 1192 1199 2-s2.0-77956128040 10.1136/gut.2009.197822
-
(2010)
Gut
, vol.59
, Issue.9
, pp. 1192-1199
-
-
Bauer, C.1
Duewell, P.2
Mayer, C.3
Lehr, H.A.4
Fitzgerald, K.A.5
Dauer, M.6
Tschopp, J.7
Endres, S.8
Latz, E.9
Schnurr, M.10
-
54
-
-
84856957894
-
Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity
-
2-s2.0-84856957894 10.1038/nature10809
-
Henao-Mejia J., Elinav E., Jin C., Hao L., Mehal W. Z., Strowig T., Thaiss C. A., Kau A. L., Eisenbarth S. C., Jurczak M. J., Camporez J.-P., Shulman G. I., Gordon J. I., Hoffman H. M., Flavell R. A., Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity. Nature 2012 482 7384 179 185 2-s2.0-84856957894 10.1038/nature10809
-
(2012)
Nature
, vol.482
, Issue.7384
, pp. 179-185
-
-
Henao-Mejia, J.1
Elinav, E.2
Jin, C.3
Hao, L.4
Mehal, W.Z.5
Strowig, T.6
Thaiss, C.A.7
Kau, A.L.8
Eisenbarth, S.C.9
Jurczak, M.J.10
Camporez, J.-P.11
Shulman, G.I.12
Gordon, J.I.13
Hoffman, H.M.14
Flavell, R.A.15
-
55
-
-
0034939382
-
Elevated interleukin-18 levels in the urine of nephrotic patients
-
DOI 10.1159/000046017
-
Matsumoto K., Kanmatsuse K., Elevated interleukin-18 levels in the urine of nephrotic patients. Nephron 2001 88 4 334 339 2-s2.0-0034939382 10.1159/000046017 (Pubitemid 32695889)
-
(2001)
Nephron
, vol.88
, Issue.4
, pp. 334-339
-
-
Matsumoto, K.1
Kanmatsuse, K.2
-
56
-
-
0038826504
-
Interleukin-18, interleukin-18 binding protein and impaired production of interferon-γ in chronic renal failure
-
Lonnemann G., Novick D., Rubinstein M., Dinarello C. A., Interleukin-18, interleukin-18 binding protein and impaired production of interferon- γ in chronic renal failure. Clinical Nephrology 2003 60 5 327 334 2-s2.0-0038826504 (Pubitemid 37407690)
-
(2003)
Clinical Nephrology
, vol.60
, Issue.5
, pp. 327-334
-
-
Lonnemann, G.1
Novick, D.2
Rubinstein, M.3
Dinarello, C.A.4
-
57
-
-
35348940695
-
IL-18 is expressed in the intercalated cell of human kidney
-
DOI 10.1038/sj.ki.5002473, PII 5002473
-
Gauer S., Sichler O., Obermüller N., Holzmann Y., Kiss E., Sobkowiak E., Pfeilschifter J., Geiger H., Mühl H., Hauser I. A., IL-18 is expressed in the intercalated cell of human kidney. Kidney International 2007 72 9 1081 1087 2-s2.0-35348940695 10.1038/sj.ki.5002473 (Pubitemid 47609039)
-
(2007)
Kidney International
, vol.72
, Issue.9
, pp. 1081-1087
-
-
Gauer, S.1
Sichler, O.2
Obermuller, N.3
Holzmann, Y.4
Kiss, E.5
Sobkowiak, E.6
Pfeilschifter, J.7
Geiger, H.8
Muhl, H.9
Hauser, I.A.10
-
58
-
-
77957887259
-
The NLRP3 inflammasome promotes renal inflammation and contributes to CKD
-
2-s2.0-77957887259 10.1681/ASN.2010020143
-
Vilaysane A., Chun J., Seamone M. E., Wang W., Chin R., Hirota S., Li Y., Clark S. A., Tschopp J., Trpkov K., Hemmelgarn B. R., Beck P. L., Muruve D. A., The NLRP3 inflammasome promotes renal inflammation and contributes to CKD. Journal of the American Society of Nephrology 2010 21 10 1732 1744 2-s2.0-77957887259 10.1681/ASN.2010020143
-
(2010)
Journal of the American Society of Nephrology
, vol.21
, Issue.10
, pp. 1732-1744
-
-
Vilaysane, A.1
Chun, J.2
Seamone, M.E.3
Wang, W.4
Chin, R.5
Hirota, S.6
Li, Y.7
Clark, S.A.8
Tschopp, J.9
Trpkov, K.10
Hemmelgarn, B.R.11
Beck, P.L.12
Muruve, D.A.13
-
59
-
-
79957773993
-
The inflammasomes in kidney disease
-
2-s2.0-79957773993 10.1681/ASN.2010080798
-
Anders H.-J., Muruve D. A., The inflammasomes in kidney disease. Journal of the American Society of Nephrology 2011 22 6 1007 1018 2-s2.0-79957773993 10.1681/ASN.2010080798
-
(2011)
Journal of the American Society of Nephrology
, vol.22
, Issue.6
, pp. 1007-1018
-
-
Anders, H.-J.1
Muruve, D.A.2
-
60
-
-
84872027781
-
Reversal of the deleterious effects of chronic dietary HFCS-55 intake by PPAR-delta agonism correlates with impaired NLRP3 inflammasome activation
-
Collino M., Benetti E., Rogazzo M., Mastrocola R., Yaqoob M. M., Aragno M., Thiemermann C., Fantozzi R., Reversal of the deleterious effects of chronic dietary HFCS-55 intake by PPAR-delta agonism correlates with impaired NLRP3 inflammasome activation. Biochemical Pharmacology 2013 85 257 264
-
(2013)
Biochemical Pharmacology
, vol.85
, pp. 257-264
-
-
Collino, M.1
Benetti, E.2
Rogazzo, M.3
Mastrocola, R.4
Yaqoob, M.M.5
Aragno, M.6
Thiemermann, C.7
Fantozzi, R.8
-
61
-
-
77957554717
-
Molecular mechanism of NLRP3 inflammasome activation
-
2-s2.0-77957554717 10.1007/s10875-010-9440-3
-
Jin C., Flavell R. A., Molecular mechanism of NLRP3 inflammasome activation. Journal of Clinical Immunology 2010 30 5 628 631 2-s2.0-77957554717 10.1007/s10875-010-9440-3
-
(2010)
Journal of Clinical Immunology
, vol.30
, Issue.5
, pp. 628-631
-
-
Jin, C.1
Flavell, R.A.2
-
62
-
-
84860681550
-
Allopurinol, quercetin and rutin ameliorate renal NLRP3 inflammasome activation and lipid accumulation in fructose-fed rats
-
2-s2.0-84858964593 10.1016/j.bcp.2012.03.005
-
Hu Q.-H., Zhang X., Pan Y., Li Y.-C., Kong L.-D., Allopurinol, quercetin and rutin ameliorate renal NLRP3 inflammasome activation and lipid accumulation in fructose-fed rats. Biochemical Pharmacology 2012 84 113 125 2-s2.0-84858964593 10.1016/j.bcp.2012.03.005
-
(2012)
Biochemical Pharmacology
, vol.84
, pp. 113-125
-
-
Hu, Q.-H.1
Zhang, X.2
Pan, Y.3
Li, Y.-C.4
Kong, L.-D.5
-
63
-
-
77953207754
-
Inflammasome up-regulation and activation in dysferlin-deficient skeletal muscle
-
2-s2.0-77953207754 10.2353/ajpath.2010.090058
-
Rawat R., Cohen T. V., Ampong B., Francia D., Henriques-Pons A., Hoffman E. P., Nagaraju K., Inflammasome up-regulation and activation in dysferlin-deficient skeletal muscle. American Journal of Pathology 2010 176 6 2891 2900 2-s2.0-77953207754 10.2353/ajpath.2010.090058
-
(2010)
American Journal of Pathology
, vol.176
, Issue.6
, pp. 2891-2900
-
-
Rawat, R.1
Cohen, T.V.2
Ampong, B.3
Francia, D.4
Henriques-Pons, A.5
Hoffman, E.P.6
Nagaraju, K.7
-
64
-
-
84862776702
-
A PGC1- α -dependent myokine that drives brown-fat-like development of white fat and thermogenesis
-
2-s2.0-84856218208 10.1038/nature10777
-
Boström P., Wu J., Jedrychowski M. P., Korde A., Ye L., Lo J. C., Rasbach K. A., Boström E. A., Choi J. H., Long J. Z., Kajimura S., Zingaretti M. C., Vind B. F., Tu H., Cinti S., Højlund K., Gygi S. P., Spiegelman B. M., A PGC1- α -dependent myokine that drives brown-fat-like development of white fat and thermogenesis. Nature 2012 481 7382 463 468 2-s2.0-84856218208 10.1038/nature10777
-
(2012)
Nature
, vol.481
, Issue.7382
, pp. 463-468
-
-
Boström, P.1
Wu, J.2
Jedrychowski, M.P.3
Korde, A.4
Ye, L.5
Lo, J.C.6
Rasbach, K.A.7
Boström, E.A.8
Choi, J.H.9
Long, J.Z.10
Kajimura, S.11
Zingaretti, M.C.12
Vind, B.F.13
Tu, H.14
Cinti, S.15
Højlund, K.16
Gygi, S.P.17
Spiegelman, B.M.18
-
65
-
-
0034121666
-
Decreased expression of interleukin-1α, interleukin-1β, and cell adhesion molecules in muscle tissue following corticosteroid treatment in patients with polymyositis and dermatomyositis
-
DOI 10.1002/1529-0131(200002)43:2<336::AID-ANR13>3.0.CO;2-V
-
Lundberg I., Kratz A. K., Alexanderson H., Patarroyo M., Decreased expression of interleukin-1alpha, interleukin-1beta, and cell adhesion molecules in muscle tissue following corticosteroid treatment in patients with polymyositis and dermatomyositis. Arthritis & Rheumatism 2000 43 336 348 (Pubitemid 30395742)
-
(2000)
Arthritis and Rheumatism
, vol.43
, Issue.2
, pp. 336-348
-
-
Lundberg, I.1
Kratz, A.-K.2
Alexanderson, H.3
Patarroyo, M.4
-
66
-
-
33748678594
-
Interleukin-18 overexpression as a hallmark of the activity of autoimmune inflammatory myopathies
-
DOI 10.1111/j.1365-2249.2006.03180.x
-
Tucci M., Quatraro C., Dammacco F., Silvestris F., Interleukin-18 overexpression as a hallmark of the activity of autoimmune inflammatory myopathies. Clinical and Experimental Immunology 2006 146 1 21 31 2-s2.0-33748678594 10.1111/j.1365-2249.2006.03180.x (Pubitemid 44393834)
-
(2006)
Clinical and Experimental Immunology
, vol.146
, Issue.1
, pp. 21-31
-
-
Tucci, M.1
Quatraro, C.2
Dammacco, F.3
Silvestris, F.4
-
67
-
-
44949140698
-
Interrelation of inflammation and APP in sIBM: IL-1 β induces accumulation of β -amyloid in skeletal muscle
-
2-s2.0-44949140698 10.1093/brain/awn053
-
Schmidt J., Barthel K., Wrede A., Salajegheh M., Bähr M., Dalakas M. C., Interrelation of inflammation and APP in sIBM: IL-1 β induces accumulation of β -amyloid in skeletal muscle. Brain 2008 131 5 1228 1240 2-s2.0-44949140698 10.1093/brain/awn053
-
(2008)
Brain
, vol.131
, Issue.5
, pp. 1228-1240
-
-
Schmidt, J.1
Barthel, K.2
Wrede, A.3
Salajegheh, M.4
Bähr, M.5
Dalakas, M.C.6
-
68
-
-
0037021505
-
The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men
-
DOI 10.1001/jama.288.21.2709
-
Lakka H.-M., Laaksonen D. E., Lakka T. A., Niskanen L. K., Kumpusalo E., Tuomilehto J., Salonen J. T., The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men. The Journal of the American Medical Association 2002 288 21 2709 2716 2-s2.0-0037021505 10.1001/jama.288.21.2709 (Pubitemid 35403784)
-
(2002)
Journal of the American Medical Association
, vol.288
, Issue.21
, pp. 2709-2716
-
-
Lakka, H.-M.1
Laaksonen, D.E.2
Lakka, T.A.3
Niskanen, L.K.4
Kumpusalo, E.5
Tuomilehto, J.6
Salonen, J.T.7
-
69
-
-
0034837376
-
Cardiovascular morbidity and mortality associated with the metabolic syndrome
-
Isomaa B., Almgren P., Tuomi T., Forsén B., Lahti K., Nissén M., Taskinen M.-R., Groop L., Cardiovascular morbidity and mortality associated with the metabolic syndrome. Diabetes Care 2001 24 4 683 689 2-s2.0-0034837376 (Pubitemid 32893993)
-
(2001)
Diabetes Care
, vol.24
, Issue.4
, pp. 683-689
-
-
Isomaa, B.1
Almgren, P.2
Tuomi, T.3
Forsen, B.4
Lahti, K.5
Nissen, M.6
Taskinen, M.-R.7
Groop, L.8
-
70
-
-
70449364536
-
Prediction of coronary heart disease risk in a general, pre-diabetic, and diabetic population during 10 years of follow-up: Accuracy of the Framingham, SCORE, and UKPDS risk functions - The Hoorn Study
-
2-s2.0-70449364536 10.2337/dc09-0745
-
van der Heijden A. A. W. A., Ortegon M. M., Niessen L. W., Nijpels G., Dekker J. M., Prediction of coronary heart disease risk in a general, pre-diabetic, and diabetic population during 10 years of follow-up: accuracy of the Framingham, SCORE, and UKPDS risk functions-The Hoorn Study. Diabetes Care 2009 32 11 2094 2098 2-s2.0-70449364536 10.2337/dc09-0745
-
(2009)
Diabetes Care
, vol.32
, Issue.11
, pp. 2094-2098
-
-
Van Der Heijden, A.A.W.A.1
Ortegon, M.M.2
Niessen, L.W.3
Nijpels, G.4
Dekker, J.M.5
-
71
-
-
0035957009
-
Inhibition of caspase 1 reduces human myocardial ischemic dysfunction via inhibition of IL-18 and IL-1β
-
DOI 10.1073/pnas.041611398
-
Pomerantz B. J., Reznikov L. L., Harken A. H., Dinarello C. A., Inhibition of caspase 1 reduces human myocardial ischemic dysfunction via inhibition of IL-18 and IL-1 β Proceedings of the National Academy of Sciences of the United States of America 2001 98 5 2871 2876 2-s2.0-0035957009 10.1073/pnas.041611398 (Pubitemid 32209576)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.5
, pp. 2871-2876
-
-
Pomerantz, B.J.1
Reznikov, L.L.2
Harken, A.H.3
Dinarello, C.A.4
-
72
-
-
12444309815
-
Targeted deletion of caspase-1 reduces early mortality and left ventricular dilatation following myocardial infarction
-
DOI 10.1016/S0022-2828(03)00113-5
-
Frantz S., Ducharme A., Sawyer D., Rohde L. E., Kobzik L., Fukazawa R., Tracey D., Allen H., Lee R. T., Kelly R. A., Targeted deletion of caspase-1 reduces early mortality and left ventricular dilatation following myocardial infarction. Journal of Molecular and Cellular Cardiology 2003 35 6 685 694 2-s2.0-12444309815 10.1016/S0022-2828(03)00113-5 (Pubitemid 36677452)
-
(2003)
Journal of Molecular and Cellular Cardiology
, vol.35
, Issue.6
, pp. 685-694
-
-
Frantz, S.1
Ducharme, A.2
Sawyer, D.3
Rohde, L.E.4
Kobzik, L.5
Fukazawa, R.6
Tracey, D.7
Allen, H.8
Lee, R.T.9
Kelly, R.A.10
-
73
-
-
20344388514
-
Proapoptotic effects of caspase-1/interleukin-converting enzyme dominate in myocardial ischemia
-
DOI 10.1161/01.RES.0000166925.45995.ed
-
Syed F. M., Hahn H. S., Odley A., Guo Y., Vallejo J. G., Lynch R. A., Mann D. L., Bolli R., Dorn G. W. II, Proapoptotic effects of caspase-1/interleukin-converting enzyme dominate in myocardial ischemia. Circulation Research 2005 96 10 1103 1109 2-s2.0-20344388514 10.1161/01.RES.0000166925.45995.ed (Pubitemid 40791383)
-
(2005)
Circulation Research
, vol.96
, Issue.10
, pp. 1103-1109
-
-
Syed, F.M.1
Hahn, H.S.2
Odley, A.3
Guo, Y.4
Vallejo, J.G.5
Lynch, R.A.6
Mann, D.L.7
Bolli, R.8
Dorn II, G.W.9
-
74
-
-
33947714585
-
A role for caspase-1 in heart failure
-
DOI 10.1161/01.RES.0000260203.55077.61
-
Merkle S., Frantz S., Schön M. P., Bauersachs J., Buitrago M., Frost R. J. A., Schmitteckert E. M., Lohse M. J., Engelhardt S., A role for caspase-1 in heart failure. Circulation Research 2007 100 5 645 653 2-s2.0-33947714585 10.1161/01.RES.0000260203.55077.61 (Pubitemid 46594878)
-
(2007)
Circulation Research
, vol.100
, Issue.5
, pp. 645-653
-
-
Merkle, S.1
Frantz, S.2
Schon, M.P.3
Bauersachs, J.4
Buitrago, M.5
Frost, R.J.A.6
Schmitteckert, E.M.7
Lohse, M.J.8
Engelhardt, S.9
-
75
-
-
79951679204
-
Inflammasome activation of cardiac fibroblasts is essential for myocardial ischemia/reperfusion injury
-
2-s2.0-79951679204 10.1161/CIRCULATIONAHA.110.982777
-
Kawaguchi M., Takahashi M., Hata T., Kashima Y., Usui F., Morimoto H., Izawa A., Takahashi Y., Masumoto J., Koyama J., Hongo M., Noda T., Nakayama J., Sagara J., Taniguchi S., Ikeda U., Inflammasome activation of cardiac fibroblasts is essential for myocardial ischemia/reperfusion injury. Circulation 2011 123 6 594 604 2-s2.0-79951679204 10.1161/CIRCULATIONAHA.110.982777
-
(2011)
Circulation
, vol.123
, Issue.6
, pp. 594-604
-
-
Kawaguchi, M.1
Takahashi, M.2
Hata, T.3
Kashima, Y.4
Usui, F.5
Morimoto, H.6
Izawa, A.7
Takahashi, Y.8
Masumoto, J.9
Koyama, J.10
Hongo, M.11
Noda, T.12
Nakayama, J.13
Sagara, J.14
Taniguchi, S.15
Ikeda, U.16
-
76
-
-
83755195135
-
The inflammasome promotes adverse cardiac remodeling following acute myocardial infarction in the mouse
-
2-s2.0-83755195135 10.1073/pnas.1108586108
-
Mezzaroma E., Toldo S., Farkas D., Seropian I. M., Van Tassell B. W., Salloum F. N., Kannan H. R., Menna A. C., Voelkel N. F., Abbate A., The inflammasome promotes adverse cardiac remodeling following acute myocardial infarction in the mouse. Proceedings of the National Academy of Sciences of the United States of America 2011 108 49 19725 19730 2-s2.0-83755195135 10.1073/pnas.1108586108
-
(2011)
Proceedings of the National Academy of Sciences of the United States of America
, vol.108
, Issue.49
, pp. 19725-19730
-
-
Mezzaroma, E.1
Toldo, S.2
Farkas, D.3
Seropian, I.M.4
Van Tassell, B.W.5
Salloum, F.N.6
Kannan, H.R.7
Menna, A.C.8
Voelkel, N.F.9
Abbate, A.10
-
77
-
-
73949118676
-
Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome
-
2-s2.0-73949118676 10.1073/pnas.0908698106
-
Iyer S. S., Pulskens W. P., Sadler J. J., Butter L. M., Teske G. J., Ulland T. K., Eisenbarth S. C., Florquin S., Flavell R. A., Leemans J. C., Sutterwala F. S., Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome. Proceedings of the National Academy of Sciences of the United States of America 2009 106 48 20388 20393 2-s2.0-73949118676 10.1073/pnas.0908698106
-
(2009)
Proceedings of the National Academy of Sciences of the United States of America
, vol.106
, Issue.48
, pp. 20388-20393
-
-
Iyer, S.S.1
Pulskens, W.P.2
Sadler, J.J.3
Butter, L.M.4
Teske, G.J.5
Ulland, T.K.6
Eisenbarth, S.C.7
Florquin, S.8
Flavell, R.A.9
Leemans, J.C.10
Sutterwala, F.S.11
-
78
-
-
78650659200
-
An inflammasome-independent role for epithelial-expressed Nlrp3 in renal ischemia-reperfusion injury
-
Shigeoka A. A., Mueller J. L., Kambo A., An inflammasome-independent role for epithelial-expressed Nlrp3 in renal ischemia-reperfusion injury. The Journal of Immunology 2010 185 6277 6285
-
(2010)
The Journal of Immunology
, vol.185
, pp. 6277-6285
-
-
Shigeoka, A.A.1
Mueller, J.L.2
Kambo, A.3
|