-
1
-
-
78649815100
-
The conundrum of inhibitory signaling by ITAM-containing immunoreceptors: potential molecular mechanisms
-
Waterman P.M., Cambier J.C. The conundrum of inhibitory signaling by ITAM-containing immunoreceptors: potential molecular mechanisms. FEBS Lett 2010, 584:4878-4882.
-
(2010)
FEBS Lett
, vol.584
, pp. 4878-4882
-
-
Waterman, P.M.1
Cambier, J.C.2
-
2
-
-
34247895443
-
Fc receptor-like molecules
-
Davis R.S. Fc receptor-like molecules. Annu Rev Immunol 2007, 25:525-560.
-
(2007)
Annu Rev Immunol
, vol.25
, pp. 525-560
-
-
Davis, R.S.1
-
3
-
-
49249103754
-
Immunoreceptor tyrosine-based inhibition motifs: a quest in the past and future
-
Daeron M., Jaeger S., Du Pasquier L., Vivier E. Immunoreceptor tyrosine-based inhibition motifs: a quest in the past and future. Immunol Rev 2008, 224:11-43.
-
(2008)
Immunol Rev
, vol.224
, pp. 11-43
-
-
Daeron, M.1
Jaeger, S.2
Du Pasquier, L.3
Vivier, E.4
-
4
-
-
61849153316
-
SHP-1 and SHP-2 in T cells: two phosphatases functioning at many levels
-
Lorenz U. SHP-1 and SHP-2 in T cells: two phosphatases functioning at many levels. Immunol Rev 2009, 228:342-359.
-
(2009)
Immunol Rev
, vol.228
, pp. 342-359
-
-
Lorenz, U.1
-
5
-
-
84861161715
-
Role of inhibitory BCR co-receptors in immunity
-
Tsubata T. Role of inhibitory BCR co-receptors in immunity. Infect Disord Drug Targets 2012, 12:181-190.
-
(2012)
Infect Disord Drug Targets
, vol.12
, pp. 181-190
-
-
Tsubata, T.1
-
6
-
-
0027769335
-
Inhibition of the activity of protein tyrosine phosphate 1C by its SH2 domains
-
Townley R., Shen S.H., Banville D., Ramachandran C. Inhibition of the activity of protein tyrosine phosphate 1C by its SH2 domains. Biochemistry 1993, 32:13414-13418.
-
(1993)
Biochemistry
, vol.32
, pp. 13414-13418
-
-
Townley, R.1
Shen, S.H.2
Banville, D.3
Ramachandran, C.4
-
7
-
-
0028989144
-
Identification of the tyrosine phosphatase PTP1C as a B cell antigen receptor-associated protein involved in the regulation of B cell signaling
-
Pani G., Kozlowski M., Cambier J.C., Mills G.B., Siminovitch K.A. Identification of the tyrosine phosphatase PTP1C as a B cell antigen receptor-associated protein involved in the regulation of B cell signaling. J Exp Med 1995, 181:2077-2084.
-
(1995)
J Exp Med
, vol.181
, pp. 2077-2084
-
-
Pani, G.1
Kozlowski, M.2
Cambier, J.C.3
Mills, G.B.4
Siminovitch, K.A.5
-
8
-
-
34447624878
-
B cell-specific deletion of protein-tyrosine phosphatase Shp1 promotes B-1a cell development and causes systemic autoimmunity
-
Pao L.I., Lam K.P., Henderson J.M., Kutok J.L., Alimzhanov M., Nitschke L., Thomas M.L., Neel B.G., Rajewsky K. B cell-specific deletion of protein-tyrosine phosphatase Shp1 promotes B-1a cell development and causes systemic autoimmunity. Immunity 2007, 27:35-48.
-
(2007)
Immunity
, vol.27
, pp. 35-48
-
-
Pao, L.I.1
Lam, K.P.2
Henderson, J.M.3
Kutok, J.L.4
Alimzhanov, M.5
Nitschke, L.6
Thomas, M.L.7
Neel, B.G.8
Rajewsky, K.9
-
9
-
-
78649869141
-
SHP-1 in T cells limits the production of CD8 effector cells without impacting the formation of long-lived central memory cells
-
Fowler C.C., Pao L.I., Blattman J.N., Greenberg P.D. SHP-1 in T cells limits the production of CD8 effector cells without impacting the formation of long-lived central memory cells. J Immunol 2010, 185:3256-3267.
-
(2010)
J Immunol
, vol.185
, pp. 3256-3267
-
-
Fowler, C.C.1
Pao, L.I.2
Blattman, J.N.3
Greenberg, P.D.4
-
10
-
-
54049146268
-
Positive and negative regulation of high affinity IgE receptor signaling by Src homology region 2 domain-containing phosphatase 1
-
Nakata K., Yoshimaru T., Suzuki Y., Inoue T., Ra C., Yakura H., Mizuno K. Positive and negative regulation of high affinity IgE receptor signaling by Src homology region 2 domain-containing phosphatase 1. J Immunol 2008, 181:5414-5424.
-
(2008)
J Immunol
, vol.181
, pp. 5414-5424
-
-
Nakata, K.1
Yoshimaru, T.2
Suzuki, Y.3
Inoue, T.4
Ra, C.5
Yakura, H.6
Mizuno, K.7
-
11
-
-
84864324543
-
Programmed cell death 1 forms negative costimulatory microclusters that directly inhibit T cell receptor signaling by recruiting phosphatase SHP2
-
Yokosuka T., Takamatsu M., Kobayashi-Imanishi W., Hashimoto-Tane A., Azuma M., Saito T. Programmed cell death 1 forms negative costimulatory microclusters that directly inhibit T cell receptor signaling by recruiting phosphatase SHP2. J Exp Med 2012, 209:1201-1217.
-
(2012)
J Exp Med
, vol.209
, pp. 1201-1217
-
-
Yokosuka, T.1
Takamatsu, M.2
Kobayashi-Imanishi, W.3
Hashimoto-Tane, A.4
Azuma, M.5
Saito, T.6
-
12
-
-
10744223870
-
Shp2 regulates SRC family kinase activity and Ras/Erk activation by controlling Csk recruitment
-
Zhang S.Q., Yang W., Kontaridis M.I., Bivona T.G., Wen G., Araki T., Luo J., Thompson J.A., Schraven B.L., Philips M.R., et al. Shp2 regulates SRC family kinase activity and Ras/Erk activation by controlling Csk recruitment. Mol Cell 2004, 13:341-355.
-
(2004)
Mol Cell
, vol.13
, pp. 341-355
-
-
Zhang, S.Q.1
Yang, W.2
Kontaridis, M.I.3
Bivona, T.G.4
Wen, G.5
Araki, T.6
Luo, J.7
Thompson, J.A.8
Schraven, B.L.9
Philips, M.R.10
-
13
-
-
84863681700
-
Shp2 activates Fyn and Ras to regulate RBL-2H3 mast cell activation following FcepsilonRI aggregation
-
Fang X., Lang Y., Wang Y., Mo W., Wei H., Xie J., Yu M. Shp2 activates Fyn and Ras to regulate RBL-2H3 mast cell activation following FcepsilonRI aggregation. PLoS ONE 2012, 7:e40566.
-
(2012)
PLoS ONE
, vol.7
-
-
Fang, X.1
Lang, Y.2
Wang, Y.3
Mo, W.4
Wei, H.5
Xie, J.6
Yu, M.7
-
14
-
-
76149129273
-
SH2 domain-containing phosphatase-2 protein-tyrosine phosphatase promotes Fc epsilon RI-induced activation of Fyn and Erk pathways leading to TNF alpha release from bone marrow-derived mast cells
-
McPherson V.A., Sharma N., Everingham S., Smith J., Zhu H.H., Feng G.S., Craig A.W. SH2 domain-containing phosphatase-2 protein-tyrosine phosphatase promotes Fc epsilon RI-induced activation of Fyn and Erk pathways leading to TNF alpha release from bone marrow-derived mast cells. J Immunol 2009, 183:4940-4947.
-
(2009)
J Immunol
, vol.183
, pp. 4940-4947
-
-
McPherson, V.A.1
Sharma, N.2
Everingham, S.3
Smith, J.4
Zhu, H.H.5
Feng, G.S.6
Craig, A.W.7
-
15
-
-
84864025903
-
SH2 domain-containing phosphatase 2 is a critical regulator of connective tissue mast cell survival and homeostasis in mice
-
Sharma N., Kumar V., Everingham S., Mali R.S., Kapur R., Zeng L.F., Zhang Z.Y., Feng G.S., Hartmann K., Roers A., et al. SH2 domain-containing phosphatase 2 is a critical regulator of connective tissue mast cell survival and homeostasis in mice. Mol Cell Biol 2012, 32:2653-2663.
-
(2012)
Mol Cell Biol
, vol.32
, pp. 2653-2663
-
-
Sharma, N.1
Kumar, V.2
Everingham, S.3
Mali, R.S.4
Kapur, R.5
Zeng, L.F.6
Zhang, Z.Y.7
Feng, G.S.8
Hartmann, K.9
Roers, A.10
-
16
-
-
0034610982
-
A dual role for Src homology 2 domain-containing inositol-5-phosphatase (SHIP) in immunity: aberrant development and enhanced function of b lymphocytes in ship-/- mice
-
Helgason C.D., Kalberer C.P., Damen J.E., Chappel S.M., Pineault N., Krystal G., Humphries R.K. A dual role for Src homology 2 domain-containing inositol-5-phosphatase (SHIP) in immunity: aberrant development and enhanced function of b lymphocytes in ship-/- mice. J Exp Med 2000, 191:781-794.
-
(2000)
J Exp Med
, vol.191
, pp. 781-794
-
-
Helgason, C.D.1
Kalberer, C.P.2
Damen, J.E.3
Chappel, S.M.4
Pineault, N.5
Krystal, G.6
Humphries, R.K.7
-
17
-
-
0032530195
-
The src homology 2-containing inositol phosphatase (SHIP) is the gatekeeper of mast cell degranulation
-
Huber M., Helgason C.D., Damen J.E., Liu L., Humphries R.K., Krystal G. The src homology 2-containing inositol phosphatase (SHIP) is the gatekeeper of mast cell degranulation. Proc Natl Acad Sci U S A 1998, 95:11330-11335.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 11330-11335
-
-
Huber, M.1
Helgason, C.D.2
Damen, J.E.3
Liu, L.4
Humphries, R.K.5
Krystal, G.6
-
18
-
-
33750530393
-
T cell receptor for antigen induces linker for activation of T cell-dependent activation of a negative signaling complex involving Dok-2, SHIP-1, and Grb-2
-
Dong S., Corre B., Foulon E., Dufour E., Veillette A., Acuto O., Michel F. T cell receptor for antigen induces linker for activation of T cell-dependent activation of a negative signaling complex involving Dok-2, SHIP-1, and Grb-2. J Exp Med 2006, 203:2509-2518.
-
(2006)
J Exp Med
, vol.203
, pp. 2509-2518
-
-
Dong, S.1
Corre, B.2
Foulon, E.3
Dufour, E.4
Veillette, A.5
Acuto, O.6
Michel, F.7
-
19
-
-
34547402441
-
T cell-specific deletion of the inositol phosphatase SHIP reveals its role in regulating Th1/Th2 and cytotoxic responses
-
Tarasenko T., Kole H.K., Chi A.W., Mentink-Kane M.M., Wynn T.A., Bolland S. T cell-specific deletion of the inositol phosphatase SHIP reveals its role in regulating Th1/Th2 and cytotoxic responses. Proc Natl Acad Sci U S A 2007, 104:11382-11387.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 11382-11387
-
-
Tarasenko, T.1
Kole, H.K.2
Chi, A.W.3
Mentink-Kane, M.M.4
Wynn, T.A.5
Bolland, S.6
-
20
-
-
0033710778
-
The RasGAP-binding protein p62dok is a mediator of inhibitory FcgammaRIIB signals in B cells
-
Tamir I., Stolpa J.C., Helgason C.D., Nakamura K., Bruhns P., Daeron M., Cambier J.C. The RasGAP-binding protein p62dok is a mediator of inhibitory FcgammaRIIB signals in B cells. Immunity 2000, 12:347-358.
-
(2000)
Immunity
, vol.12
, pp. 347-358
-
-
Tamir, I.1
Stolpa, J.C.2
Helgason, C.D.3
Nakamura, K.4
Bruhns, P.5
Daeron, M.6
Cambier, J.C.7
-
21
-
-
0034194516
-
Differential regulation of B cell development, activation, and death by the src homology 2 domain-containing 5' inositol phosphatase (SHIP)
-
Brauweiler A., Tamir I., Dal Porto J., Benschop R.J., Helgason C.D., Humphries R.K., Freed J.H., Cambier J.C. Differential regulation of B cell development, activation, and death by the src homology 2 domain-containing 5' inositol phosphatase (SHIP). J Exp Med 2000, 191:1545-1554.
-
(2000)
J Exp Med
, vol.191
, pp. 1545-1554
-
-
Brauweiler, A.1
Tamir, I.2
Dal Porto, J.3
Benschop, R.J.4
Helgason, C.D.5
Humphries, R.K.6
Freed, J.H.7
Cambier, J.C.8
-
22
-
-
84873749079
-
Aberrant antibody affinity selection in SHIP-deficient B cells
-
Leung W.H., Tarasenko T., Biesova Z., Kole H., Walsh E.R., Bolland S. Aberrant antibody affinity selection in SHIP-deficient B cells. Eur J Immunol 2013, 43:371-381.
-
(2013)
Eur J Immunol
, vol.43
, pp. 371-381
-
-
Leung, W.H.1
Tarasenko, T.2
Biesova, Z.3
Kole, H.4
Walsh, E.R.5
Bolland, S.6
-
23
-
-
79960406249
-
A balance of Bruton's tyrosine kinase and SHIP activation regulates B cell receptor cluster formation by controlling actin remodeling
-
Liu C., Miller H., Hui K.L., Grooman B., Bolland S., Upadhyaya A., Song W. A balance of Bruton's tyrosine kinase and SHIP activation regulates B cell receptor cluster formation by controlling actin remodeling. J Immunol 2011, 187:230-239.
-
(2011)
J Immunol
, vol.187
, pp. 230-239
-
-
Liu, C.1
Miller, H.2
Hui, K.L.3
Grooman, B.4
Bolland, S.5
Upadhyaya, A.6
Song, W.7
-
24
-
-
84871835887
-
Quorum sensing contributes to activated IgM-secreting B, cell homeostasis
-
Montaudouin C., Anson M., Hao Y., Duncker S.V., Fernandez T., Gaudin E., Ehrenstein M., Kerr W.G., Colle J.H., Bruhns P., et al. Quorum sensing contributes to activated IgM-secreting B, cell homeostasis. J Immunol 2013, 190:106-114.
-
(2013)
J Immunol
, vol.190
, pp. 106-114
-
-
Montaudouin, C.1
Anson, M.2
Hao, Y.3
Duncker, S.V.4
Fernandez, T.5
Gaudin, E.6
Ehrenstein, M.7
Kerr, W.G.8
Colle, J.H.9
Bruhns, P.10
-
25
-
-
81955161811
-
Monophosphorylation of CD79a and CD79b ITAM motifs initiates a SHIP-1 phosphatase-mediated inhibitory signaling cascade required for B cell anergy
-
O'Neill S.K., Getahun A., Gauld S.B., Merrell K.T., Tamir I., Smith M.J., Dal Porto J.M., Li Q.Z., Cambier J.C. Monophosphorylation of CD79a and CD79b ITAM motifs initiates a SHIP-1 phosphatase-mediated inhibitory signaling cascade required for B cell anergy. Immunity 2011, 35:746-756.
-
(2011)
Immunity
, vol.35
, pp. 746-756
-
-
O'Neill, S.K.1
Getahun, A.2
Gauld, S.B.3
Merrell, K.T.4
Tamir, I.5
Smith, M.J.6
Dal Porto, J.M.7
Li, Q.Z.8
Cambier, J.C.9
-
26
-
-
84861692916
-
B cell receptor signal transduction in the GC is short-circuited by high phosphatase activity
-
Khalil A.M., Cambier J.C., Shlomchik M.J. B cell receptor signal transduction in the GC is short-circuited by high phosphatase activity. Science 2012, 336:1178-1181.
-
(2012)
Science
, vol.336
, pp. 1178-1181
-
-
Khalil, A.M.1
Cambier, J.C.2
Shlomchik, M.J.3
-
27
-
-
0032478126
-
The paired Ig-like receptor PIR-B is an inhibitory receptor that recruits the protein-tyrosine phosphatase SHP-1
-
Blery M., Kubagawa H., Chen C.C., Vely F., Cooper M.D., Vivier E. The paired Ig-like receptor PIR-B is an inhibitory receptor that recruits the protein-tyrosine phosphatase SHP-1. Proc Natl Acad Sci U S A 1998, 95:2446-2451.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 2446-2451
-
-
Blery, M.1
Kubagawa, H.2
Chen, C.C.3
Vely, F.4
Cooper, M.D.5
Vivier, E.6
-
28
-
-
33947282140
-
Cutting edge: acute and chronic exposure of immature B cells to antigen leads to impaired homing and SHIP1-dependent reduction in stromal cell-derived factor-1 responsiveness
-
Brauweiler A., Merrell K., Gauld S.B., Cambier J.C. Cutting edge: acute and chronic exposure of immature B cells to antigen leads to impaired homing and SHIP1-dependent reduction in stromal cell-derived factor-1 responsiveness. J Immunol 2007, 178:3353-3357.
-
(2007)
J Immunol
, vol.178
, pp. 3353-3357
-
-
Brauweiler, A.1
Merrell, K.2
Gauld, S.B.3
Cambier, J.C.4
-
29
-
-
34547193611
-
B-cell anergy: from transgenic models to naturally occurring anergic B cells?
-
Cambier J.C., Gauld S.B., Merrell K.T., Vilen B.J. B-cell anergy: from transgenic models to naturally occurring anergic B cells?. Nat Rev Immunol 2007, 7:633-643.
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 633-643
-
-
Cambier, J.C.1
Gauld, S.B.2
Merrell, K.T.3
Vilen, B.J.4
-
30
-
-
27544458293
-
Maintenance of B cell anergy requires constant antigen receptor occupancy and signaling
-
Gauld S.B., Benschop R.J., Merrell K.T., Cambier J.C. Maintenance of B cell anergy requires constant antigen receptor occupancy and signaling. Nat Immunol 2005, 6:1160-1167.
-
(2005)
Nat Immunol
, vol.6
, pp. 1160-1167
-
-
Gauld, S.B.1
Benschop, R.J.2
Merrell, K.T.3
Cambier, J.C.4
-
31
-
-
0033404953
-
Partially phosphorylated T cell receptor zeta molecules can inhibit T cell activation
-
Kersh E.N., Kersh G.J., Allen P.M. Partially phosphorylated T cell receptor zeta molecules can inhibit T cell activation. J Exp Med 1999, 190:1627-1636.
-
(1999)
J Exp Med
, vol.190
, pp. 1627-1636
-
-
Kersh, E.N.1
Kersh, G.J.2
Allen, P.M.3
-
32
-
-
19944430878
-
Identification of FcalphaRI as an inhibitory receptor that controls inflammation: dual role of FcRgamma ITAM
-
Pasquier B., Launay P., Kanamaru Y., Moura I.C., Pfirsch S., Ruffie C., Henin D., Benhamou M., Pretolani M., Blank U., et al. Identification of FcalphaRI as an inhibitory receptor that controls inflammation: dual role of FcRgamma ITAM. Immunity 2005, 22:31-42.
-
(2005)
Immunity
, vol.22
, pp. 31-42
-
-
Pasquier, B.1
Launay, P.2
Kanamaru, Y.3
Moura, I.C.4
Pfirsch, S.5
Ruffie, C.6
Henin, D.7
Benhamou, M.8
Pretolani, M.9
Blank, U.10
-
33
-
-
57649126096
-
Differential dephosphorylation of the FcRgamma immunoreceptor tyrosine-based activation motif tyrosines with dissimilar potential for activating Syk
-
Yamashita T., Suzuki R., Backlund P.S., Yamashita Y., Yergey A.L., Rivera J. Differential dephosphorylation of the FcRgamma immunoreceptor tyrosine-based activation motif tyrosines with dissimilar potential for activating Syk. J Biol Chem 2008, 283:28584-28594.
-
(2008)
J Biol Chem
, vol.283
, pp. 28584-28594
-
-
Yamashita, T.1
Suzuki, R.2
Backlund, P.S.3
Yamashita, Y.4
Yergey, A.L.5
Rivera, J.6
-
34
-
-
70449701417
-
Suppression of phosphatidylinositol 3,4,5-trisphosphate production is a key determinant of B cell anergy
-
Browne C.D., Del Nagro C.J., Cato M.H., Dengler H.S., Rickert R.C. Suppression of phosphatidylinositol 3,4,5-trisphosphate production is a key determinant of B cell anergy. Immunity 2009, 31:749-760.
-
(2009)
Immunity
, vol.31
, pp. 749-760
-
-
Browne, C.D.1
Del Nagro, C.J.2
Cato, M.H.3
Dengler, H.S.4
Rickert, R.C.5
-
35
-
-
34548330713
-
Small-molecule agonists of SHIP1 inhibit the phosphoinositide 3-kinase pathway in hematopoietic cells
-
Ong C.J., Ming-Lum A., Nodwell M., Ghanipour A., Yang L., Williams D.E., Kim J., Demirjian L., Qasimi P., Ruschmann J., et al. Small-molecule agonists of SHIP1 inhibit the phosphoinositide 3-kinase pathway in hematopoietic cells. Blood 2007, 110:1942-1949.
-
(2007)
Blood
, vol.110
, pp. 1942-1949
-
-
Ong, C.J.1
Ming-Lum, A.2
Nodwell, M.3
Ghanipour, A.4
Yang, L.5
Williams, D.E.6
Kim, J.7
Demirjian, L.8
Qasimi, P.9
Ruschmann, J.10
-
36
-
-
84867214110
-
Interaction of TAPP adapter proteins with phosphatidylinositol (3,4)-bisphosphate regulates B-cell activation and autoantibody production
-
Landego I., Jayachandran N., Wullschleger S., Zhang T.T., Gibson I.W., Miller A., Alessi D.R., Marshall A.J. Interaction of TAPP adapter proteins with phosphatidylinositol (3,4)-bisphosphate regulates B-cell activation and autoantibody production. Eur J Immunol 2012, 42:2760-2770.
-
(2012)
Eur J Immunol
, vol.42
, pp. 2760-2770
-
-
Landego, I.1
Jayachandran, N.2
Wullschleger, S.3
Zhang, T.T.4
Gibson, I.W.5
Miller, A.6
Alessi, D.R.7
Marshall, A.J.8
-
37
-
-
84874622748
-
Activation/inhibition of mast cells by supra-optimal antigen concentrations
-
Huber M. Activation/inhibition of mast cells by supra-optimal antigen concentrations. Cell Commun Signal: CCS 2013, 11:7.
-
(2013)
Cell Commun Signal: CCS
, vol.11
, pp. 7
-
-
Huber, M.1
-
38
-
-
0030946792
-
The negative signaling molecule SH2 domain-containing inositol-polyphosphate 5-phosphatase (SHIP) binds to the tyrosine-phosphorylated beta subunit of the high affinity IgE receptor
-
Kimura T., Sakamoto H., Appella E., Siraganian R.P. The negative signaling molecule SH2 domain-containing inositol-polyphosphate 5-phosphatase (SHIP) binds to the tyrosine-phosphorylated beta subunit of the high affinity IgE receptor. J Biol Chem 1997, 272:13991-13996.
-
(1997)
J Biol Chem
, vol.272
, pp. 13991-13996
-
-
Kimura, T.1
Sakamoto, H.2
Appella, E.3
Siraganian, R.P.4
-
39
-
-
84860316777
-
The role of SHIP in the development and activation of mouse mucosal and connective tissue mast cells
-
Ruschmann J., Antignano F., Lam V., Snyder K., Kim C., Essak M., Zhang A., Lin A.H., Mali R.S., Kapur R., et al. The role of SHIP in the development and activation of mouse mucosal and connective tissue mast cells. J Immunol 2012, 188:3839-3850.
-
(2012)
J Immunol
, vol.188
, pp. 3839-3850
-
-
Ruschmann, J.1
Antignano, F.2
Lam, V.3
Snyder, K.4
Kim, C.5
Essak, M.6
Zhang, A.7
Lin, A.H.8
Mali, R.S.9
Kapur, R.10
-
40
-
-
68949112048
-
SHIP1 is a repressor of mast cell hyperplasia, cytokine production, and allergic inflammation in vivo
-
Haddon D.J., Antignano F., Hughes M.R., Blanchet M.R., Zbytnuik L., Krystal G., McNagny K.M. SHIP1 is a repressor of mast cell hyperplasia, cytokine production, and allergic inflammation in vivo. J Immunol 2009, 183:228-236.
-
(2009)
J Immunol
, vol.183
, pp. 228-236
-
-
Haddon, D.J.1
Antignano, F.2
Hughes, M.R.3
Blanchet, M.R.4
Zbytnuik, L.5
Krystal, G.6
McNagny, K.M.7
-
41
-
-
0035400142
-
Partially distinct molecular mechanisms mediate inhibitory FcgammaRIIB signaling in resting and activated B cells
-
Brauweiler A., Tamir I., Marschner S., Helgason C.D., Cambier J.C. Partially distinct molecular mechanisms mediate inhibitory FcgammaRIIB signaling in resting and activated B cells. J Immunol 2001, 167:204-211.
-
(2001)
J Immunol
, vol.167
, pp. 204-211
-
-
Brauweiler, A.1
Tamir, I.2
Marschner, S.3
Helgason, C.D.4
Cambier, J.C.5
-
42
-
-
34250874425
-
The inositol 5'-phosphatase SHIP-2 negatively regulates IgE-induced mast cell degranulation and cytokine production
-
Leung W.H., Bolland S. The inositol 5'-phosphatase SHIP-2 negatively regulates IgE-induced mast cell degranulation and cytokine production. J Immunol 2007, 179:95-102.
-
(2007)
J Immunol
, vol.179
, pp. 95-102
-
-
Leung, W.H.1
Bolland, S.2
-
43
-
-
67651163434
-
Cultured peripheral blood mast cells from chronic idiopathic urticaria patients spontaneously degranulate upon IgE sensitization: relationship to expression of Syk and SHIP-2
-
Saini S.S., Paterniti M., Vasagar K., Gibbons S.P., Sterba P.M., Vonakis B.M. Cultured peripheral blood mast cells from chronic idiopathic urticaria patients spontaneously degranulate upon IgE sensitization: relationship to expression of Syk and SHIP-2. Clin Immunol 2009, 132:342-348.
-
(2009)
Clin Immunol
, vol.132
, pp. 342-348
-
-
Saini, S.S.1
Paterniti, M.2
Vasagar, K.3
Gibbons, S.P.4
Sterba, P.M.5
Vonakis, B.M.6
-
44
-
-
77949962019
-
CD45-Csk phosphatase-kinase titration uncouples basal and inducible T cell receptor signaling during thymic development
-
Zikherman J., Jenne C., Watson S., Doan K., Raschke W., Goodnow C.C., Weiss A. CD45-Csk phosphatase-kinase titration uncouples basal and inducible T cell receptor signaling during thymic development. Immunity 2010, 32:342-354.
-
(2010)
Immunity
, vol.32
, pp. 342-354
-
-
Zikherman, J.1
Jenne, C.2
Watson, S.3
Doan, K.4
Raschke, W.5
Goodnow, C.C.6
Weiss, A.7
-
45
-
-
84856014500
-
Quantitative differences in CD45 expression unmask functions for CD45 in B-cell development, tolerance, and survival
-
Zikherman J., Doan K., Parameswaran R., Raschke W., Weiss A. Quantitative differences in CD45 expression unmask functions for CD45 in B-cell development, tolerance, and survival. Proc Natl Acad Sci U S A 2012, 109:E3-E12.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
-
-
Zikherman, J.1
Doan, K.2
Parameswaran, R.3
Raschke, W.4
Weiss, A.5
-
46
-
-
79959358205
-
Regulation of Src family kinases involved in T cell receptor signaling by protein-tyrosine phosphatase CD148
-
Stepanek O., Kalina T., Draber P., Skopcova T., Svojgr K., Angelisova P., Horejsi V., Weiss A., Brdicka T. Regulation of Src family kinases involved in T cell receptor signaling by protein-tyrosine phosphatase CD148. J Biol Chem 2011, 286:22101-22112.
-
(2011)
J Biol Chem
, vol.286
, pp. 22101-22112
-
-
Stepanek, O.1
Kalina, T.2
Draber, P.3
Skopcova, T.4
Svojgr, K.5
Angelisova, P.6
Horejsi, V.7
Weiss, A.8
Brdicka, T.9
-
47
-
-
0032531528
-
Negative regulation of human T cell activation by the receptor-type protein tyrosine phosphatase CD148
-
Tangye S.G., Wu J., Aversa G., de Vries J.E., Lanier L.L., Phillips J.H. Negative regulation of human T cell activation by the receptor-type protein tyrosine phosphatase CD148. J Immunol 1998, 161:3803-3807.
-
(1998)
J Immunol
, vol.161
, pp. 3803-3807
-
-
Tangye, S.G.1
Wu, J.2
Aversa, G.3
de Vries, J.E.4
Lanier, L.L.5
Phillips, J.H.6
-
48
-
-
39149139617
-
Structurally distinct phosphatases CD45 and CD148 both regulate B cell and macrophage immunoreceptor signaling
-
Zhu J.W., Brdicka T., Katsumoto T.R., Lin J., Weiss A. Structurally distinct phosphatases CD45 and CD148 both regulate B cell and macrophage immunoreceptor signaling. Immunity 2008, 28:183-196.
-
(2008)
Immunity
, vol.28
, pp. 183-196
-
-
Zhu, J.W.1
Brdicka, T.2
Katsumoto, T.R.3
Lin, J.4
Weiss, A.5
-
49
-
-
67349238172
-
Requirement for CD45 in fine-tuning mast cell responses mediated by different ligand-receptor systems
-
Grochowy G., Hermiston M.L., Kuhny M., Weiss A., Huber M. Requirement for CD45 in fine-tuning mast cell responses mediated by different ligand-receptor systems. Cell Signal 2009, 21:1277-1286.
-
(2009)
Cell Signal
, vol.21
, pp. 1277-1286
-
-
Grochowy, G.1
Hermiston, M.L.2
Kuhny, M.3
Weiss, A.4
Huber, M.5
-
50
-
-
78650672157
-
PTPalpha activates Lyn and Fyn and suppresses Hck to negatively regulate FcepsilonRI-dependent mast cell activation and allergic responses
-
Samayawardhena L.A., Pallen C.J. PTPalpha activates Lyn and Fyn and suppresses Hck to negatively regulate FcepsilonRI-dependent mast cell activation and allergic responses. J Immunol 2010, 185:5993-6002.
-
(2010)
J Immunol
, vol.185
, pp. 5993-6002
-
-
Samayawardhena, L.A.1
Pallen, C.J.2
-
51
-
-
0033521596
-
Cooperative inhibition of T-cell antigen receptor signaling by a complex between a kinase and a phosphatase
-
Cloutier J.F., Veillette A. Cooperative inhibition of T-cell antigen receptor signaling by a complex between a kinase and a phosphatase. J Exp Med 1999, 189:111-121.
-
(1999)
J Exp Med
, vol.189
, pp. 111-121
-
-
Cloutier, J.F.1
Veillette, A.2
-
52
-
-
33744949634
-
Identification of substrates of human protein-tyrosine phosphatase PTPN22
-
Wu J., Katrekar A., Honigberg L.A., Smith A.M., Conn M.T., Tang J., Jeffery D., Mortara K., Sampang J., Williams S.R., et al. Identification of substrates of human protein-tyrosine phosphatase PTPN22. J Biol Chem 2006, 281:11002-11010.
-
(2006)
J Biol Chem
, vol.281
, pp. 11002-11010
-
-
Wu, J.1
Katrekar, A.2
Honigberg, L.A.3
Smith, A.M.4
Conn, M.T.5
Tang, J.6
Jeffery, D.7
Mortara, K.8
Sampang, J.9
Williams, S.R.10
-
53
-
-
84855764414
-
PEST-domain-enriched tyrosine phosphatase and glucocorticoids as regulators of anaphylaxis in mice
-
Obiri D.D., Flink N., Maier J.V., Neeb A., Maddalo D., Thiele W., Menon A., Stassen M., Kulkarni R.A., Garabedian M.J., et al. PEST-domain-enriched tyrosine phosphatase and glucocorticoids as regulators of anaphylaxis in mice. Allergy 2012, 67:175-182.
-
(2012)
Allergy
, vol.67
, pp. 175-182
-
-
Obiri, D.D.1
Flink, N.2
Maier, J.V.3
Neeb, A.4
Maddalo, D.5
Thiele, W.6
Menon, A.7
Stassen, M.8
Kulkarni, R.A.9
Garabedian, M.J.10
-
54
-
-
65449176044
-
Cutting edge: the PTPN22 allelic variant associated with autoimmunity impairs B cell signaling
-
Arechiga A.F., Habib T., He Y., Zhang X., Zhang Z.Y., Funk A., Buckner J.H. Cutting edge: the PTPN22 allelic variant associated with autoimmunity impairs B cell signaling. J Immunol 2009, 182:3343-3347.
-
(2009)
J Immunol
, vol.182
, pp. 3343-3347
-
-
Arechiga, A.F.1
Habib, T.2
He, Y.3
Zhang, X.4
Zhang, Z.Y.5
Funk, A.6
Buckner, J.H.7
-
55
-
-
28444469783
-
Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant
-
Vang T., Congia M., Macis M.D., Musumeci L., Orru V., Zavattari P., Nika K., Tautz L., Tasken K., Cucca F., et al. Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant. Nat Genet 2005, 37:1317-1319.
-
(2005)
Nat Genet
, vol.37
, pp. 1317-1319
-
-
Vang, T.1
Congia, M.2
Macis, M.D.3
Musumeci, L.4
Orru, V.5
Zavattari, P.6
Nika, K.7
Tautz, L.8
Tasken, K.9
Cucca, F.10
-
56
-
-
84877115482
-
The PTPN22 risk variant promotes systemic autoimmunity in murine models
-
Dai X., James R.G., Habib T., Singh S., Jackson S., Khim S., Moon R.T., Liggitt D., Wolf-Yadlin A., Buckner J.H., et al. The PTPN22 risk variant promotes systemic autoimmunity in murine models. J Clin Invest 2013, 123:2024-2036.
-
(2013)
J Clin Invest
, vol.123
, pp. 2024-2036
-
-
Dai, X.1
James, R.G.2
Habib, T.3
Singh, S.4
Jackson, S.5
Khim, S.6
Moon, R.T.7
Liggitt, D.8
Wolf-Yadlin, A.9
Buckner, J.H.10
-
57
-
-
80052239824
-
The autoimmune disease-associated PTPN22 variant promotes calpain-mediated Lyp/Pep degradation associated with lymphocyte and dendritic cell hyperresponsiveness
-
Zhang J., Zahir N., Jiang Q., Miliotis H., Heyraud S., Meng X., Dong B., Xie G., Qiu F., Hao Z., et al. The autoimmune disease-associated PTPN22 variant promotes calpain-mediated Lyp/Pep degradation associated with lymphocyte and dendritic cell hyperresponsiveness. Nat Genet 2011, 43:902-907.
-
(2011)
Nat Genet
, vol.43
, pp. 902-907
-
-
Zhang, J.1
Zahir, N.2
Jiang, Q.3
Miliotis, H.4
Heyraud, S.5
Meng, X.6
Dong, B.7
Xie, G.8
Qiu, F.9
Hao, Z.10
-
58
-
-
29144480861
-
Protein tyrosine phosphatase alpha regulates Fyn activity and Cbp/PAG phosphorylation in thymocyte lipid rafts
-
Maksumova L., Le H.T., Muratkhodjaev F., Davidson D., Veillette A., Pallen C.J. Protein tyrosine phosphatase alpha regulates Fyn activity and Cbp/PAG phosphorylation in thymocyte lipid rafts. J Immunol 2005, 175:7947-7956.
-
(2005)
J Immunol
, vol.175
, pp. 7947-7956
-
-
Maksumova, L.1
Le, H.T.2
Muratkhodjaev, F.3
Davidson, D.4
Veillette, A.5
Pallen, C.J.6
-
59
-
-
84055191068
-
T cell protein tyrosine phosphatase attenuates T cell signaling to maintain tolerance in mice
-
Wiede F., Shields B.J., Chew S.H., Kyparissoudis K., van Vliet C., Galic S., Tremblay M.L., Russell S.M., Godfrey D.I., Tiganis T. T cell protein tyrosine phosphatase attenuates T cell signaling to maintain tolerance in mice. J Clin Invest 2011, 121:4758-4774.
-
(2011)
J Clin Invest
, vol.121
, pp. 4758-4774
-
-
Wiede, F.1
Shields, B.J.2
Chew, S.H.3
Kyparissoudis, K.4
van Vliet, C.5
Galic, S.6
Tremblay, M.L.7
Russell, S.M.8
Godfrey, D.I.9
Tiganis, T.10
-
60
-
-
70450224447
-
SHP-1 exhibits a pro-apoptotic function in antigen-stimulated mast cells: positive regulation of mitochondrial death pathways and negative regulation of survival signaling pathways
-
Inoue T., Suzuki Y., Mizuno K., Nakata K., Yoshimaru T., Ra C. SHP-1 exhibits a pro-apoptotic function in antigen-stimulated mast cells: positive regulation of mitochondrial death pathways and negative regulation of survival signaling pathways. Mol Immunol 2009, 47:222-232.
-
(2009)
Mol Immunol
, vol.47
, pp. 222-232
-
-
Inoue, T.1
Suzuki, Y.2
Mizuno, K.3
Nakata, K.4
Yoshimaru, T.5
Ra, C.6
-
61
-
-
0029904138
-
Direct regulation of ZAP-70 by SHP-1 in T cell antigen receptor signaling
-
Plas D.R., Johnson R., Pingel J.T., Matthews R.J., Dalton M., Roy G., Chan A.C., Thomas M.L. Direct regulation of ZAP-70 by SHP-1 in T cell antigen receptor signaling. Science 1996, 272:1173-1176.
-
(1996)
Science
, vol.272
, pp. 1173-1176
-
-
Plas, D.R.1
Johnson, R.2
Pingel, J.T.3
Matthews, R.J.4
Dalton, M.5
Roy, G.6
Chan, A.C.7
Thomas, M.L.8
-
62
-
-
84874585981
-
SHP-1 phosphatase activity counteracts increased T cell receptor affinity
-
Hebeisen M., Baitsch L., Presotto D., Baumgaertner P., Romero P., Michielin O., Speiser D.E., Rufer N. SHP-1 phosphatase activity counteracts increased T cell receptor affinity. J Clin Invest 2013, 123:1044-1056.
-
(2013)
J Clin Invest
, vol.123
, pp. 1044-1056
-
-
Hebeisen, M.1
Baitsch, L.2
Presotto, D.3
Baumgaertner, P.4
Romero, P.5
Michielin, O.6
Speiser, D.E.7
Rufer, N.8
-
63
-
-
0035923535
-
PD-1 immunoreceptor inhibits B cell receptor-mediated signaling by recruiting src homology 2-domain-containing tyrosine phosphatase 2 to phosphotyrosine
-
Okazaki T., Maede A., Nishimura H., Kurosaki T., Honjo T. PD-1 immunoreceptor inhibits B cell receptor-mediated signaling by recruiting src homology 2-domain-containing tyrosine phosphatase 2 to phosphotyrosine. Proc Natl Acad Sci U S A 2001, 98:13866-13871.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 13866-13871
-
-
Okazaki, T.1
Maede, A.2
Nishimura, H.3
Kurosaki, T.4
Honjo, T.5
-
64
-
-
77955868530
-
The phosphatase PTP-PEST promotes secondary T cell responses by dephosphorylating the protein tyrosine kinase Pyk2
-
Davidson D., Shi X., Zhong M.C., Rhee I., Veillette A. The phosphatase PTP-PEST promotes secondary T cell responses by dephosphorylating the protein tyrosine kinase Pyk2. Immunity 2010, 33:167-180.
-
(2010)
Immunity
, vol.33
, pp. 167-180
-
-
Davidson, D.1
Shi, X.2
Zhong, M.C.3
Rhee, I.4
Veillette, A.5
-
65
-
-
0035796465
-
PTP-PEST, a scaffold protein tyrosine phosphatase, negatively regulates lymphocyte activation by targeting a unique set of substrates
-
Davidson D., Veillette A. PTP-PEST, a scaffold protein tyrosine phosphatase, negatively regulates lymphocyte activation by targeting a unique set of substrates. EMBO 2001, 20:3414-3426.
-
(2001)
EMBO
, vol.20
, pp. 3414-3426
-
-
Davidson, D.1
Veillette, A.2
-
66
-
-
43449128867
-
TCR-induced downregulation of protein tyrosine phosphatase PEST augments secondary T cell responses
-
Arimura Y., Vang T., Tautz L., Williams S., Mustelin T. TCR-induced downregulation of protein tyrosine phosphatase PEST augments secondary T cell responses. Mol Immunol 2008, 45:3074-3084.
-
(2008)
Mol Immunol
, vol.45
, pp. 3074-3084
-
-
Arimura, Y.1
Vang, T.2
Tautz, L.3
Williams, S.4
Mustelin, T.5
-
67
-
-
64549090699
-
Protein tyrosine phosphatase epsilon is a negative regulator of FcepsilonRI-mediated mast cell responses
-
Akimoto M., Mishra K., Lim K.T., Tani N., Hisanaga S.I., Katagiri T., Elson A., Mizuno K., Yakura H. Protein tyrosine phosphatase epsilon is a negative regulator of FcepsilonRI-mediated mast cell responses. Scand J Immunol 2009, 69:401-411.
-
(2009)
Scand J Immunol
, vol.69
, pp. 401-411
-
-
Akimoto, M.1
Mishra, K.2
Lim, K.T.3
Tani, N.4
Hisanaga, S.I.5
Katagiri, T.6
Elson, A.7
Mizuno, K.8
Yakura, H.9
-
68
-
-
84863295500
-
Once phosphorylated, tyrosines in carboxyl terminus of protein-tyrosine kinase Syk interact with signaling proteins, including TULA-2, a negative regulator of mast cell degranulation
-
de Castro R.O., Zhang J., Groves J.R., Barbu E.A., Siraganian R.P. Once phosphorylated, tyrosines in carboxyl terminus of protein-tyrosine kinase Syk interact with signaling proteins, including TULA-2, a negative regulator of mast cell degranulation. J Biol Chem 2012, 287:8194-8204.
-
(2012)
J Biol Chem
, vol.287
, pp. 8194-8204
-
-
de Castro, R.O.1
Zhang, J.2
Groves, J.R.3
Barbu, E.A.4
Siraganian, R.P.5
-
69
-
-
84872485396
-
Negative control of mast cell degranulation and the anaphylactic response by the phosphatase lipin1
-
Shin J., Zhang P., Wang S., Wu J., Guan Z., Zhong X.P. Negative control of mast cell degranulation and the anaphylactic response by the phosphatase lipin1. Eur J Immunol 2013, 43:240-248.
-
(2013)
Eur J Immunol
, vol.43
, pp. 240-248
-
-
Shin, J.1
Zhang, P.2
Wang, S.3
Wu, J.4
Guan, Z.5
Zhong, X.P.6
-
70
-
-
33646007018
-
Cutting edge: lentiviral short hairpin RNA silencing of PTEN in human mast cells reveals constitutive signals that promote cytokine secretion and cell survival
-
Furumoto Y., Brooks S., Olivera A., Takagi Y., Miyagishi M., Taira K., Casellas R., Beaven M.A., Gilfillan A.M., Rivera J. Cutting edge: lentiviral short hairpin RNA silencing of PTEN in human mast cells reveals constitutive signals that promote cytokine secretion and cell survival. J Immunol 2006, 176:5167-5171.
-
(2006)
J Immunol
, vol.176
, pp. 5167-5171
-
-
Furumoto, Y.1
Brooks, S.2
Olivera, A.3
Takagi, Y.4
Miyagishi, M.5
Taira, K.6
Casellas, R.7
Beaven, M.A.8
Gilfillan, A.M.9
Rivera, J.10
-
71
-
-
81555208939
-
PTEN deficiency in mast cells causes a mastocytosis-like proliferative disease that heightens allergic responses and vascular permeability
-
Furumoto Y., Charles N., Olivera A., Leung W.H., Dillahunt S., Sargent J.L., Tinsley K., Odom S., Scott E., Wilson T.M., et al. PTEN deficiency in mast cells causes a mastocytosis-like proliferative disease that heightens allergic responses and vascular permeability. Blood 2011, 118:5466-5475.
-
(2011)
Blood
, vol.118
, pp. 5466-5475
-
-
Furumoto, Y.1
Charles, N.2
Olivera, A.3
Leung, W.H.4
Dillahunt, S.5
Sargent, J.L.6
Tinsley, K.7
Odom, S.8
Scott, E.9
Wilson, T.M.10
-
72
-
-
0037342166
-
Pten inactivation alters peripheral B lymphocyte fate and reconstitutes CD19 function
-
Anzelon A.N., Wu H., Rickert R.C. Pten inactivation alters peripheral B lymphocyte fate and reconstitutes CD19 function. Nat Immunol 2003, 4:287-294.
-
(2003)
Nat Immunol
, vol.4
, pp. 287-294
-
-
Anzelon, A.N.1
Wu, H.2
Rickert, R.C.3
-
73
-
-
0034995242
-
T cell-specific loss of Pten leads to defects in central and peripheral tolerance
-
Suzuki A., Yamaguchi M.T., Ohteki T., Sasaki T., Kaisho T., Kimura Y., Yoshida R., Wakeham A., Higuchi T., Fukumoto M., et al. T cell-specific loss of Pten leads to defects in central and peripheral tolerance. Immunity 2001, 14:523-534.
-
(2001)
Immunity
, vol.14
, pp. 523-534
-
-
Suzuki, A.1
Yamaguchi, M.T.2
Ohteki, T.3
Sasaki, T.4
Kaisho, T.5
Kimura, Y.6
Yoshida, R.7
Wakeham, A.8
Higuchi, T.9
Fukumoto, M.10
-
74
-
-
77954981351
-
Distinct roles for PTEN in prevention of T cell lymphoma and autoimmunity in mice
-
Liu X., Karnell J.L., Yin B., Zhang R., Zhang J., Li P., Choi Y., Maltzman J.S., Pear W.S., Bassing C.H., et al. Distinct roles for PTEN in prevention of T cell lymphoma and autoimmunity in mice. J Clin Invest 2010, 120:2497-2507.
-
(2010)
J Clin Invest
, vol.120
, pp. 2497-2507
-
-
Liu, X.1
Karnell, J.L.2
Yin, B.3
Zhang, R.4
Zhang, J.5
Li, P.6
Choi, Y.7
Maltzman, J.S.8
Pear, W.S.9
Bassing, C.H.10
-
75
-
-
78149294363
-
Coordinate suppression of B cell lymphoma by PTEN and SHIP phosphatases
-
Miletic A.V., Anzelon-Mills A.N., Mills D.M., Omori S.A., Pedersen I.M., Shin D.M., Ravetch J.V., Bolland S., Morse H.C., Rickert R.C. Coordinate suppression of B cell lymphoma by PTEN and SHIP phosphatases. J Exp Med 2010, 207:2407-2420.
-
(2010)
J Exp Med
, vol.207
, pp. 2407-2420
-
-
Miletic, A.V.1
Anzelon-Mills, A.N.2
Mills, D.M.3
Omori, S.A.4
Pedersen, I.M.5
Shin, D.M.6
Ravetch, J.V.7
Bolland, S.8
Morse, H.C.9
Rickert, R.C.10
-
76
-
-
44849107712
-
Non-T cell activation linker promotes mast cell survival by dampening the recruitment of SHIP1 by linker for activation of T cells
-
Roget K., Malissen M., Malbec O., Malissen B., Daeron M. Non-T cell activation linker promotes mast cell survival by dampening the recruitment of SHIP1 by linker for activation of T cells. J Immunol 2008, 180:3689-3698.
-
(2008)
J Immunol
, vol.180
, pp. 3689-3698
-
-
Roget, K.1
Malissen, M.2
Malbec, O.3
Malissen, B.4
Daeron, M.5
|