A disease-associated PTPN22 variant promotes systemic autoimmunity in murine models

Journal of Clinical Investigation

Volumn 123, Issue 5, 2013, Pages 2024-2036

  Dai, Xuezhi ^a,b   James, Richard G ^a   Habib, Tania ^c   Singh, Swati ^a,b   Jackson, Shaun ^a,b   Khim, Socheath ^a,b   Moon, Randall T ^a   Liggitt, Denny ^a   Wolf Yadlin, Alejandro ^a   Buckner, Jane H ^c   Rawlings, David J ^a,b  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b SEATTLE CHILDREN S RESEARCH INSTITUTE   (United States)

^c BENAROYA RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; NON RECEPTOR PROTEIN TYROSINE PHOSPHATASE 22;

AGE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOIMMUNE DISEASE; AUTOIMMUNITY; B LYMPHOCYTE; CELL EXPANSION; CELL LINEAGE; CELL SELECTION; CONTROLLED STUDY; DISEASE ASSOCIATION; GENE EXPRESSION; GENE MUTATION; GENE TARGETING; GENETIC VARIABILITY; LYMPHOCYTE FUNCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN STABILITY; T LYMPHOCYTE;

ANIMALS; AUTOIMMUNE DISEASES; AUTOIMMUNITY; B-LYMPHOCYTES; CALCIUM; CELL LINEAGE; CELL SURVIVAL; CROSSES, GENETIC; CYCLOHEXIMIDE; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENETIC VARIATION; HOMEOSTASIS; LYMPHOCYTES; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 12; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 22; T-LYMPHOCYTES;

EID: 84877115482     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI66963     Document Type: Article

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