Programmed cell death 1 forms negative costimulatory microclusters that directly inhibit T cell receptor signaling by recruiting phosphatase SHP2

Journal of Experimental Medicine

Volumn 209, Issue 6, 2012, Pages 1201-1217

  Yokosuka, Tadashi ^a,b   Takamatsu, Masako ^a   Kobayashi Imanishi, Wakana ^a   Hashimoto Tane, Akiko ^a   Azuma, Miyuki ^c   Saito, Takashi ^a,d  

^a RIKEN Center for Integrative Medical Sciences   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^d OSAKA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

PROGRAMMED DEATH 1 RECEPTOR; PROTEIN TYROSINE PHOSPHATASE SHP 2; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEPHOSPHORYLATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; RECEPTOR INTRINSIC ACTIVITY; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, CD274; CD8-POSITIVE T-LYMPHOCYTES; LYMPHOCYTE ACTIVATION; MICE; MICE, MUTANT STRAINS; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; PROGRAMMED CELL DEATH 1 RECEPTOR; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 11; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TYROSINE;

EID: 84864324543     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20112741     Document Type: Article

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